D. Kumaran

发表

A HEX-1 crystal lattice required for Woronin body function in Neurospora crassa

S. Swaminathan, N. Chua, K. Swaminathan, 2003, Nature Structural Biology.

Structural analysis of botulinum neurotoxin type E catalytic domain and its mutant Glu212-->Gln reveals the pivotal role of the Glu212 carboxylate in the catalytic pathway.

S. Swaminathan, D. Kumaran, R. Agarwal, 2004, Biochemistry.

Structure and mechanism of ADP‐ribose‐1″‐monophosphatase (Appr‐1″‐pase), a ubiquitous cellular processing enzyme

F. Studier, S. Swaminathan, D. Kumaran, 2005, Protein science : a publication of the Protein Society.

Structural genomics of protein phosphatases

A. Sali, J. M. Sauder, A. Fiser, 2007, Journal of Structural and Functional Genomics.

Structural characterization and reversal of the natural organophosphate resistance of a D-type esterase, Saccharomyces cerevisiae S-formylglutathione hydrolase.

F. Studier, S. Swaminathan, D. Kumaran, 2008, Biochemistry.

Hepatitis C virus NS3/4A inhibitors and other drug-like compounds as covalent binders of SARS-CoV-2 main protease

M. Head, P. Adams, R. Sweet, 2022, Scientific Reports.

Potent and Selective Covalent Inhibition of the Papain-like Protease from SARS-CoV-2

Russell B. Davidson, D. Sterner, S. Pokhrel, 2022, Nature Communications.

Letter to the Editor

F. Studier, S. Swaminathan, D. Kumaran, 2005 .

Structure and enzymatic activity of botulinum neurotoxins

S. Swaminathan, D. Kumaran, S. Eswaramoorthy, 2004, Movement disorders : official journal of the Movement Disorder Society.

Role of metals in the biological activity of Clostridium botulinum neurotoxins.

S. Swaminathan, D. Kumaran, J. Keller, 2004, Biochemistry.

A novel mechanism for Clostridium botulinum neurotoxin inhibition.

S. Swaminathan, D. Kumaran, S. Eswaramoorthy, 2002, Biochemistry.

Crystal structure of a putative glycosyltransferase from Bacteroides fragilis

S. Burley, S. Swaminathan, D. Kumaran, 2007 .

1,4‐Bis(2‐hydroxy‐5‐methylbenzyl)piperazine

M. N. Ponnuswamy, D. Kumaran, H. Fun, 1999 .

Crystal structure and conformational analysis of N-formyl and N-nitroso derivatives of piperidinone

M. N. Ponnuswamy, D. Kumaran, M. Soriano-garcia, 1999 .

The Crystal Structure of the Ivy Δ4-16:0-ACP Desaturase Reveals Structural Details of the Oxidized Active Site and Potential Determinants of Regioselectivity*

Y. Lindqvist, J. Shanklin, D. Kumaran, 2007, Journal of Biological Chemistry.

Crystal structure of trehalose‐6‐phosphate phosphatase–related protein: Biochemical and biological implications

S. Burley, J. Bonanno, S. Swaminathan, 2006, Protein Science.

Crystal structure of phosphatidylglycerophosphatase (PGPase), a putative membrane‐bound lipid phosphatase, reveals a novel binuclear metal binding site and two “proton wires”

S. Burley, J. Bonanno, S. Swaminathan, 2006, Proteins.

Catalytic mechanism and three-dimensional structure of adenine deaminase.

Andrej Sali, Ashima Bagaria, Stephen K Burley, 2011, Biochemistry.

Domain organization in Clostridium botulinum neurotoxin type E is unique: its implication in faster translocation.

J. Navaza, S. Swaminathan, D. Kumaran, 2008, Journal of molecular biology.

Cloning, expression and purification of botulinum neurotoxin type A heavy chain – crystallographic evidence for a putative tetrameric pore

S. Swaminathan, D. Kumaran, D. Lakshminarasimhan, 2012 .

Structure- and Substrate-based Inhibitor Design for Clostridium botulinum Neurotoxin Serotype A*

S. Swaminathan, D. Kumaran, M. L. Ludivico, 2008, Journal of Biological Chemistry.

Structural analysis of the catalytic domain of tetanus neurotoxin.

S. Swaminathan, D. Kumaran, Krishnamurthy N. Rao, 2005, Toxicon : official journal of the International Society on Toxinology.

The temperature-dependent conformational ensemble of SARS-CoV-2 main protease (Mpro)

D. Keedy, A. Ebrahim, D. Kumaran, 2022, IUCrJ.

The temperature-dependent conformational ensemble of SARS-CoV-2 main protease (Mpro)

D. Keedy, A. Ebrahim, S. McSweeney, 2021, bioRxiv.

Cloning, high level expression, purification, and crystallization of the full length Clostridium botulinum neurotoxin type E light chain.

John J Dunn, S. Swaminathan, J. Dunn, 2004, Protein expression and purification.

Heterologous expression and purification of Arabidopsis thaliana VIM1 protein: in vitro evidence for its inability to recognize hydroxymethylcytosine, a rare base in Arabidopsis DNA.

J. Dunn, Chun-Xiao Song, D. Kumaran, 2012, Protein expression and purification.

Crystal structure of outer surface protein C (OspC) from the Lyme disease spirochete, Borrelia burgdorferi

S. Swaminathan, S. Koide, C. Lawson, 2001, The EMBO journal.

Crystallization and preliminary X-ray analysis of Borrelia burgdorferi outer surface protein C (OspC).

S. Swaminathan, J. Dunn, D. Kumaran, 2001, Acta crystallographica. Section D, Biological crystallography.

Functional annotation and three-dimensional structure of an incorrectly annotated dihydroorotase from cog3964 in the amidohydrolase superfamily.

Sugadev Ragumani, Magdalena Korczynska, Brian K Shoichet, 2013, Biochemistry.

Functional Annotation and Three-Dimensional Structure of an Incorrectly Annotated Dihydroorotase from cog 3964 in the Amidohydrolase Superfamily Argentina

B. Shoichet, F. Raushel, S. Swaminathan, 2012 .

A novel acetate-bound complex of human carbonic anhydrase II.

S. Swaminathan, D. Kumaran, P. Mazumdar, 2008, Acta crystallographica. Section F, Structural biology and crystallization communications.

The catalase activity of diiron adenine deaminase

J. M. Sauder, F. Raushel, S. Burley, 2011, Protein science : a publication of the Protein Society.

β-Hydroxyacyl-acyl Carrier Protein Dehydratase (FabZ) from Francisella tularensis and Yersinia pestis: Structure Determination, Enzymatic Characterization, and Cross-Inhibition Studies.

S. Swaminathan, D. Kumaran, Brian E. McGillick, 2016, Biochemistry.

Structure of staphylococcal enterotoxin C2 at various pH levels.

W Furey, S. Swaminathan, D. Kumaran, 2001, Acta crystallographica. Section D, Biological crystallography.

Potent and Selective Covalent Inhibition of the Papain-like Protease from SARS-CoV-2

Jerry M. Parks, Russell B. Davidson, M. Head, 2021, Research square.

Crystal structure of a putative CN hydrolase from yeast

F. Studier, S. Swaminathan, D. Kumaran, 2003, Proteins.

Crystallographic evidence for doxorubicin binding to the receptor-binding site in Clostridium botulinum neurotoxin B.

S. Swaminathan, D. Kumaran, S. Eswaramoorthy, 2001, Acta crystallographica. Section D, Biological crystallography.

Fast N-CO rotational equilibria in twist-boat conformations of N -ethoxycarbonyl- r- 2 , c -6-diphenylpiperidin-4-ones and N -ethoxycarbonyl- r -2, c -6-diphenylpiperidines

M. N. Ponnuswamy, D. Kumaran, M. Venkatraj, 2002 .

Crystal Structure of SARS-CoV-2 Main Protease (3CLpro/Mpro) in Complex with Covalent Inhibitor Narlaprevir

S. McSweeney, D. Kumaran, J. Jakoncic, 2020 .

Interactions of a potent cyclic peptide inhibitor with the light chain of botulinum neurotoxin A: Insights from X-ray crystallography.

S. Swaminathan, D. Kumaran, M. Krebs, 2015, Bioorganic & medicinal chemistry.

Peptide inhibitors of botulinum neurotoxin serotype A: design, inhibition, cocrystal structures, structure-activity relationship and pharmacophore modeling.

S. Swaminathan, D. Kumaran, G. Kumar, 2012, Acta crystallographica. Section D, Biological crystallography.

Substrate Binding Mode and Its Implication on Drug Design for Botulinum Neurotoxin A

Richa Rawat, S. Swaminathan, D. Kumaran, 2008, PLoS pathogens.

Structural basis for a ribofuranosyl binding protein: Insights into the furanose specific transport

S. Burley, S. Swaminathan, D. Kumaran, 2011, Proteins.

Functional annotation of two new carboxypeptidases from the amidohydrolase superfamily of enzymes.

J. M. Sauder, F. Raushel, S. Burley, 2009, Biochemistry.

The crystal structure of bovine liver catalase without NADPH

S. Swaminathan, K. Sekar, D. Kumaran, 2005 .

Crystal structure of a putative lysostaphin peptidase from Vibrio cholerae

S. Burley, S. Swaminathan, D. Kumaran, 2008, Proteins.

Potent and selective covalent inhibition of the papain-like protease from SARS-CoV-2

Jerry M. Parks, Russell B. Davidson, D. Sterner, 2023, Nature Communications.