J. Behr

发表

Cleavage of tRNA with imidazole and spermine imidazole constructs: a new approach for probing RNA structure.

B. Felden, V. Vlassov, R. Giegé, 1995, Nucleic acids research.

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine.

D. Scherman, J. Behr, F. Lezoualc’h, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Polyethylenimine but Not Cationic Lipids Promotes Transgene Delivery to the Nucleus in Mammalian Cells*

D. Escande, S. Demolombe, J. Behr, 1998, The Journal of Biological Chemistry.

Towards synthetic viruses.

G. Zuber, J. Behr, E. Dauty, 2001, Advanced drug delivery reviews.

An amphiphilic dendrimer for effective delivery of small interfering RNA and gene silencing in vitro and in vivo.

C. Liu, J. Behr, A. Bolcato-Bellemin, 2012, Angewandte Chemie.

Synthetic gene transfer vectors II: back to the future.

Jean-Paul Behr, J. Behr, 2012, Accounts of chemical research.

Conjugating phosphospermines to siRNAs for improved stability in serum, intracellular delivery and RNAi-mediated gene silencing.

J. Behr, A. Bolcato-Bellemin, P. Erbacher, 2012, Molecular pharmaceutics.

Structurally flexible triethanolamine core PAMAM dendrimers are effective nanovectors for DNA transfection in vitro and in vivo to the mouse thymus.

Maurizio Fermeglia, Sabrina Pricl, Paola Posocco, 2011, Bioconjugate chemistry.

Cationic siRNAs provide carrier-free gene silencing in animal cells.

J. Behr, J. Rémy, M. Nothisen, 2009, Journal of the American Chemical Society.

Sticky overhangs enhance siRNA-mediated gene silencing

Jean-Paul Behr, Patrick Erbacher, J. Behr, 2007, Proceedings of the National Academy of Sciences.

Eradication of p53-mutated head and neck squamous cell carcinoma xenografts using nonviral p53 gene therapy and photochemical internalization.

Kristian Berg, François Guillemin, Jean-Paul Behr, 2006, Molecular therapy : the journal of the American Society of Gene Therapy.

PAMAM dendrimers for efficient siRNA delivery and potent gene silencing.

Ling Peng, Jean-Paul Behr, Patrick Erbacher, 2006, Chemical communications.

Nonviral gene delivery: Towards artificial viruses

J. Behr, P. Belguise-Valladier, 2001, Cytotechnology.

Molecular Vectors for Gene Delivery to Cancer Cells

G. Zuber, J. Behr, J. Rémy, 2004 .

Genuine DNA/polyethylenimine (PEI) Complexes Improve Transfection Properties and Cell Survival

J. Behr, T. Bettinger, J. Rémy, 2004, Journal of drug targeting.

Intracytoplasmic delivery of anionic proteins.

D. Dalkara, G. Zuber, J. Behr, 2004, Molecular therapy : the journal of the American Society of Gene Therapy.

Effective polyethylenimine‐mediated gene transfer into human endothelial cells

J. Behr, J. Rémy, P. Erbacher, 2004, The journal of gene medicine.

The cyclin-dependent kinase inhibitor p21cip1/waf1 enhances the cytotoxicity of ganciclovir in HSV-tk transfected ovarian carcinoma cells

J. Behr, C. Muller, C. Ziller, 2004 .

the cytotoxicity of ganciclovir in HSV-tk transfected ovarian carcinoma cells

J. Behr, C. Muller, C. Ziller, 2004 .

Polyfunctional Vectors for Gene Delivery

J. Behr, B. Demeneix, 2003 .

In vivo growth inhibitory effect of iterative wild-type p53 gene transfer in human head and neck carcinoma xenografts using glucosylated polyethylenimine nonviral vector

F. Guillemin, M. Barberi-Heyob, J. Merlin, 2002, Cancer Gene Therapy.

DNA condensation by an oxidizable cationic detergent. Interactions with lipid vesicles.

Y. Mély, J. Behr, D. Llères, 2001, Chemistry and physics of lipids.

Inhibition of hepadnaviral replication by polyethylenimine-based intravenous delivery of antisense phosphodiester oligodeoxynucleotides to the liver

M. Chevallier, J. Behr, H. Blum, 2001, Gene Therapy.

Polyethylenimine-mediated gene transfer into pancreatic tumor dissemination in the murine peritoneal cavity

Teruhiko Yoshida, J. Behr, J. Rémy, 2001, Gene Therapy.

Systemic linear polyethylenimine (L‐PEI)‐mediated gene delivery in the mouse

J. Behr, J. Rémy, P. Erbacher, 2000, The journal of gene medicine.

Ovarian carcinoma cells are effectively transfected by polyethylenimine (PEI) derivatives

J. Behr, T. Bettinger, P. Erbacher, 2000, Cancer Gene Therapy.

Gene transfer with synthetic virus-like particles via the integrin-mediated endocytosis pathway

J. Behr, J. Rémy, P. Erbacher, 1999, Gene Therapy.

Polyethylenimines: A Family of Potent Polymers for Nucleic Acid Delivery

J. Behr, A. Kichler, P. Erbacher, 1999 .

In vivo delivery to tumors of DNA complexed with linear polyethylenimine.

E. Brambilla, J. Behr, J. Coll, 1999, Human gene therapy.

Gene delivery: a single nuclear localization signal peptide is sufficient to carry DNA to the cell nucleus.

J. Behr, M. Zanta, P. Belguise-Valladier, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Transfection and physical properties of various saccharide, poly(ethylene glycol), and antibody‐derivatized polyethylenimines (PEI)

J. Behr, T. Bettinger, J. Rémy, 1999, The journal of gene medicine.

Theory and Practice of Using Polycationic Amphiphiles and polymers for In Vitro and In Vivo Gene Transfer

C. Benoist, J. Behr, B. Demeneix, 1998 .

Liver‐directed gene transfer: a linear polyethylenimine derivative mediates highly efficient DNA delivery to primary hepatocytes in vitro and in vivo

J. Behr, H. Blum, D. Moradpour, 1998, Journal of viral hepatitis.

Delivery of Polynucleotides with Polyamine Lipids and Polymers

J. Behr, B. Demeneix, O. Boussif, 1997 .

Gene Transfer with Multivalent Synthetic Vectors

J. Behr, J. Rémy, J. Remy, 1996 .

Lipospermine-based gene transfer into the newborn mouse brain is optimized by a low lipospermine/DNA charge ratio.

D. Scherman, C. Benoist, J. Behr, 1995, Human gene therapy.

[34] – Gene Transfer into Primary and Established Mammalian Cell Lines with Lipopolyamine-Coated DNA

J. Behr, J. Loeffler, 1995 .

Gene transfer with synthetic cationic amphiphiles: prospects for gene therapy.

J. Behr, Jean-Paul Behr, 1994, Bioconjugate chemistry.

Gene transfer with a series of lipophilic DNA-binding molecules.

C. Sirlin, J. Behr, J. Rémy, 1994, Bioconjugate chemistry.

Gene transfer into primary and established mammalian cell lines with lipopolyamine-coated DNA.

J. Behr, J. Loeffler, 1993, Methods in enzymology.

Gene transfer optimization with lipospermine-coated DNA.

J. Behr, J. Rémy, J. Loeffler, 1993, DNA and cell biology.

SYNTHETIC GENE-TRANSFER VECTORS

J. Behr, 1993 .

ω‐Hydrazino Linear Polyethylenimine: A Monoconjugation Building Block for Nucleic Acid Delivery

G. Zuber, J. Behr, B. Pons, 2006 .

Targeted Gene Delivery to Cancer Cells with Nanometric DNA Particles Enveloped with Folic Acid Using a Polymerisable Anchor

G. Zuber, J. Behr, C. Muller, 2005, Technology in cancer research & treatment.

Intracellular delivery of nanometric DNA particles via the folate receptor.

Jean-Paul Behr, G. Zuber, J. Behr, 2002, Bioconjugate chemistry.

Template Oligomerization of DNA-Bound Cations Produces Calibrated Nanometric Particles

J. Behr, T. Blessing, A. Remy, 1998 .

Dimerizable cationic detergents with a low cmc condense plasmid DNA into nanometric particles and transfect cells in culture.

J. Behr, J. Rémy, E. Dauty, 2001, Journal of the American Chemical Society.

Influence of membrane-active peptides on lipospermine/DNA complex mediated gene transfer.

K. Mechtler, J. Behr, E. Wagner, 1997, Bioconjugate chemistry.

The Lock-and-key principle : the state of the art -- 100 years on

J. Behr, 1994 .

Molecular Receptors. Structural Effects and Substrate Recognition in Binding of Organic and Biogenic Ammonium Ions by Chiral Polyfunctional Macrocyclic Polyethers Bearing Amino‐Acid and Other Side‐Chains

J. Behr, J. Lehn, P. Vierling, 1982 .

Molecular Structure of the Ethylenediammonium Complex of a Tetracarboxy‐macrocyclic Receptor Molecule

J. Behr, J. Lehn, J. Daly, 1981 .

Molecular Receptors. Functionalized and chiral macrocyclic polyethers derived from tartaric acid

R. Hayward, J. Behr, J. Lehn, 1980 .

Stable ammonium cryptates of chiral macrocyclic receptor molecules bearing amino-acid side-chains

J. Behr, J. Lehn, P. Vierling, 1976 .

A model for non‐viral gene delivery: through syndecan adhesion molecules and powered by actin

J. Behr, J. Rémy, I. Kopatz, 2004, The journal of gene medicine.

Enhanced gene transfer and cell death following p53 gene transfer using photochemical internalisation of glucosylated PEI‐DNA complexes

K. Berg, F. Guillemin, A. Leroux, 2004, The journal of gene medicine.

DNA strongly binds to micelles and vesicles containing lipopolyamines or lipointercalants.

J. Behr, 1986 .

Methods for probing lateral diffusion of membrane components: triplet—triplet annihilation and triplet—triplet energy transfer

J. Behr, K. Naqvi, D. Chapman, 1974 .

Conjugation of Folate via Gelonin Carbohydrate Residues Retains Ribosomal-inactivating Properties of the Toxin and Permits Targeting to Folate Receptor Positive Cells*

J. Behr, T. Bettinger, L. Seymour, 2001, The Journal of Biological Chemistry.

Synthetic Gene‐Transfer Vectors

J. Behr, 1993 .

Synthetic viruslike particles for targeted gene delivery to alphavbeta3 integrin-presenting endothelial cells.

G. Zuber, J. Behr, M. Dontenwill, 2009, Molecular Pharmaceutics.

Artificial self-assembling systems for gene delivery

M. Heller, F. Szoka, J. Behr, 1996 .

Clinical adenoviral gene therapy for prostate cancer.

Lindsay J. Georgopoulos, K. Ulbrich, A. Danielsson, 2010, Human gene therapy.

Polyethylenimine (PEI).

J. Behr, B. Demeneix, 2005, Advances in genetics.

Direct Identification of a Polyamine Binding Domain on the Regulatory Subunit of the Protein Kinase Casein Kinase 2 by Photoaffinity Labeling (*)

E. Chambaz, J. Behr, O. Filhol, 1995, The Journal of Biological Chemistry.

Targeted gene delivery to cancer cells: directed assembly of nanometric DNA particles coated with folic acid.

G. Zuber, J. Behr, E. Dauty, 2003, Angewandte Chemie.

Synthesis and hybridization properties of oligonucleotides containing polyamines at the C-2 position of purines: a pre-synthetic approach for the incorporation of spermine into oligodeoxynucleotides containing 2-(4,9,13-triazatridecyl)-2'-deoxyguanosine.

J. Behr, P. Potier, A. Abdennaji, 2000, Chemistry.

Cationic Oligospermine-Oligonucleotide Conjugates Provide Carrier-free Splice Switching in Monolayer Cells and Spheroids

J. Behr, M. Nothisen, M. Kotera, 2018, Molecular therapy. Nucleic acids.

Oligonucleotide-oligospermine conjugates (zip nucleic acids): a convenient means of finely tuning hybridization temperatures.

J. Behr, B. Pons, M. Kotera, 2008, Journal of the American Chemical Society.

Online Synthesis of Diblock Cationic Oligonucleotides for Enhanced Hybridization to their Complementary Sequence

G. Zuber, J. Behr, B. Pons, 2006, Chembiochem : a European journal of chemical biology.

Adenovirus-derived vectors for prostate cancer gene therapy.

Lindsay J. Georgopoulos, K. Ulbrich, S. Kochanek, 2010, Human gene therapy.

Nonenzymatic plasmid ligation mediated by minor groove-binding molecules.

G. Zuber, J. Behr, 1994, Biochemistry.

Deoxyribosylurea and deoxyribosylformamide oligonucleotides

J. Behr, S. Baillet, 1995 .

Location of spermine and other polyamines on DNA as revealed by photoaffinity cleavage with polyaminobenzenediazonium salts.

J. Behr, N. Schmid, 1991, Biochemistry.

Recognition of DNA sequences by strand replacement with polyamino-oligonucleotides

J. Behr, N. Schmid, 1995 .

Monomolecular DNA nanoparticles for intravenous delivery of genes.

G. Zuber, J. Behr, Liliane Zammut-Italiano, 2005, Journal of the American Chemical Society.

Dimerizable Detergents as Gene Transfer Vectors

J. Behr, E. Dauty, T. Blessing, 2000 .

The binding of divalent cations by purified gangliosides

J. Behr, J. Lehn, 1973, FEBS letters.

Carrier-mediated transport through bulk liquid membranes: dependence of transport rates and selectivity on carrier properties in a diffusion-limited process

J. Behr, J. Lehn, M. Kirch, 1985 .

The oxonium (H3O+) cation: molecular structure of an oxonium-macrocyclic polyether complex

D. Moras, P. Dumas, J. Behr, 1982 .

Intraperitoneal linear polyethylenimine (L-PEI)-mediated gene delivery to ovarian carcinoma nodes in mice

J. Behr, Y. Denoux, P. Erbacher, 2006, Cancer Gene Therapy.

omega-Hydrazino linear polyethylenimine: a monoconjugation building block for nucleic acid delivery.

G. Zuber, J. Behr, B. Pons, 2006, Chembiochem : a European journal of chemical biology.

Molecular dynamics of .alpha.-cyclodextrin inclusion complexes

J. Behr, J. Lehn, 1976 .

Towards multifunctional synthetic vectors.

J. Behr, B. Demeneix, Z. Hassani, 2004, Current gene therapy.

Macrotricyclic and macropentacyclic ditopic receptor molecules: synthesis, crystal structure and substrate binding

D. Moras, P. Dumas, M. Bergdoll, 1987 .

Crystal structure of a polyfunctional macrocyclic K+ complex provides a solid-state model of a K+ channel

D. Moras, J. Behr, J. Lehn, 1982, Nature.

Transport of amino acids through organic liquid membranes.

J. Behr, J. Lehn, 1973 .

Molecular Receptors. Functionalized and chiral macrocyclic polyethers derived from tartaric acid

R. Hayward, J. Behr, J. Lehn, 1980 .

CHIRAL AND FUNCTIONALIZED FACE-DISCRIMINATED AND SIDE-DISCRIMINATED MACROCYCLIC POLYETHERS. SYNTHESES AND CRYSTAL STRUCTURES

D. Moras, J. Behr, J. Lehn, 1981 .

Synthesis of novel macrobicyclic polyfunctional cryptands

J. Behr, J. Lehn, C. Burrows, 1985 .

Stability constants for the complexation of alkali and alkaline‐earth cations byN‐acetyl‐neuraminic acid

J. Behr, J. Lehn, 1972, FEBS letters.

Nuclear relaxation and molecular properties. Part VIII. Molecular dynamics of glycine and glycylglycine

J. Behr, J. Lehn, 1972 .

Molecular dynamics of acetylcholine and of choline.

J. Behr, J. Lehn, 1972, Biochemical and biophysical research communications.

Efficient gene delivery with neutral complexes of lipospermine and thiol-reactive phospholipids.

J. Behr, O. Boussif, B. Frisch, 1995, Biochemical and biophysical research communications.

Synthesis of 4-guanidinopyrimidine nucleosides for triple helix-mediated guanine and cytosine recognition

J. Behr, S. Doronina, 1998 .

Efficient gene transfer into mammalian primary endocrine cells with lipopolyamine-coated DNA.

J. Behr, B. Demeneix, J. Loeffler, 1989, Proceedings of the National Academy of Sciences of the United States of America.

New photoactivatable structural and affinity probes of RNAs: specific features and applications for mapping of spermine binding sites in yeast tRNA(Asp) and interaction of this tRNA with yeast aspartyl-tRNA synthetase

Richard Giegé, Angela Garcia, Jean-Paul Behr, 1990, Nucleic Acids Res..

Towards a general triple helix mediated DNA recognition scheme

J. Behr, S. Doronina, 1997 .

DNA Recognition by Non-Natural Oligonucleotides

J. Behr, S. Doronina, Stéphanie Blanalt-Feidt, 1999 .

Structure Tuning of Cationic Oligospermine-siRNA Conjugates for Carrier-Free Gene Silencing.

J. Behr, M. Nothisen, M. Kotera, 2016, Molecular pharmaceutics.

Synthesis of 4-Guanidinopyrimidine Nucleosides for Triple Helix-Mediated Guanine and Cytosine Recognition.

J. Behr, S. Doronina, 1998 .

Targeted gene transfer into hepatoma cells with lipopolyamine-condensed DNA particles presenting galactose ligands: a stage toward artificial viruses.

J. Behr, A. Kichler, F. Schuber, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Zip Nucleic Acids: new high affinity oligonucleotides as potent primers for PCR and reverse transcription

J. Behr, M. Nothisen, P. Erbacher, 2009, Nucleic acids research.

Versatile synthesis of oligodeoxyribonucleotide–oligospermine conjugates

J. Behr, M. Kotera, E. Voirin, 2007, Nature Protocols.

RECOGNITION OF DNA BY STRAND INVASION WITH OLIGONUCLEOTIDE-SPERMINE CONJUGATES

J. Behr, P. Potier, 2001, Nucleosides, nucleotides & nucleic acids.

Lipid‐mediated siRNA delivery down‐regulates exogenous gene expression in the mouse brain at picomolar levels

J. Behr, B. Demeneix, C. Giovannangeli, 2005, The journal of gene medicine.

Systemic delivery of sticky siRNAs targeting the cell cycle for lung tumor metastasis inhibition.

J. Behr, A. Bolcato-Bellemin, P. Erbacher, 2013, Journal of controlled release : official journal of the Controlled Release Society.

Lipopolyamine‐Mediated Transfection Allows Gene Expression Studies in Primary Neuronal Cells

P. Sassone-Corsi, J. Loeffler, J. Behr, 1990, Journal of neurochemistry.

Delivery systems for enhanced siRNA delivery

J. Behr, P. Erbacher, P. Neuberg, 2008 .

A powerful nonviral vector for in vivo gene transfer into the adult mammalian brain: polyethylenimine.

C. Benoist, J. Behr, B. Demeneix, 1996, Human gene therapy.

High-efficiency transfection of primary human keratinocytes with positively charged lipopolyamine:DNA complexes.

J. Behr, L. Chow, C. Staedel, 1994, The Journal of investigative dermatology.

Inhibition of Neurogenic Precursor Proliferation by Antisense Thyroid Hormone Receptor Oligonucleotides (*)

J. Behr, F. Lezoualc’h, B. Demeneix, 1995, The Journal of Biological Chemistry.

Sticky siRNAs targeting survivin and cyclin B1 exert an antitumoral effect on melanoma subcutaneous xenografts and lung metastases

J. Behr, P. Shankaranarayanan, A. Bolcato-Bellemin, 2013, BMC Cancer.

In vitro gene delivery to hepatocytes with galactosylated polyethylenimine.

J. Behr, O. Boussif, M. Zanta, 1997, Bioconjugate chemistry.

DermaVir: a novel topical vaccine for HIV/AIDS.

J. Lisziewicz, F. Lori, J. Behr, 2005, The Journal of investigative dermatology.

Nomenclature for synthetic gene delivery systems.

P. Cullis, F. Szoka, J. Behr, 1997, Human gene therapy.

Development of plasmid and oligonucleotide nanometric particles

J. Behr, E. Dauty, J. Remy, 2002, Gene Therapy.

Ca2+‐sensitive cytosolic nucleases prevent efficient delivery to the nucleus of injected plasmids

D. Escande, J. Behr, H. Pollard, 2001, The journal of gene medicine.

Induction of Potent Human Immunodeficiency Virus Type 1-Specific T-Cell-Restricted Immunity by Genetically Modified Dendritic Cells

J. Lisziewicz, F. Lori, P. Greenberg, 2001, Journal of Virology.

Monomolecular collapse of plasmid DNA into stable virus-like particles.

J. Behr, T. Blessing, J. Remy, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Photohydrolysis of DNA by polyaminobenzenediazonium salts

J. Behr, 1989 .

A photoaffinity probe for the polyamine site regulating the NMDA receptor.

S. Gambs, J. Behr, M. Goeldner, 1995, European journal of pharmacology.

Optimized galenics improve in vitro gene transfer with cationic molecules up to 1000-fold.

J. Behr, O. Boussif, M. Zanta, 1996, Gene therapy.

Polyethylenimine (PEI).

J. Behr, B. Demeneix, 2005, Advances in genetics.

SYNTHESIS OF C-4 SUBSTITUTED PYRIMIDINES EXHIBITING VARIOUS H-BONDING PATTERNS

J. Behr, S. Doronina, Stéphanie Blanalt-Feidt, 1999 .

An electron microscopy study into the mechanism of gene transfer with lipopolyamines.

E. Brambilla, J. Behr, A. Steffan, 1996, Gene therapy.

Convenient polymer-supported synthetic route to heterobifunctional polyethylene glycols.

J. Behr, T. Bettinger, P. Erbacher, 1998, Bioconjugate chemistry.

Cell-penetrating cationic siRNA and lipophilic derivatives efficient at nanomolar concentrations in the presence of serum and albumin.

J. Behr, Phanélie Perche, M. Nothisen, 2013, Journal of Controlled Release.

Enhanced rates of dihydropyridine to pyridinium hydrogen transfer in complexes of an active macrocyclic receptor molecule

J. Behr, J. Lehn, 1978 .

Selective Complexation of Ammonium and Guanidinium Salts by Synthetic Receptor Molecules

J. Behr, 1980 .

Synthetic gene transfer vectors

J. Behr, 1994 .

Improvement of nonviral p53 gene transfer in human carcinoma cells using glucosylated polyethylenimine derivatives

F. Guillemin, J. Merlin, J. Behr, 2001, Cancer Gene Therapy.

Structure of the hydrazinium complex of a tetracarboxy-18-crown-6 receptor molecule

D. Moras, J. Behr, J. Lehn, 1987 .

A Model for Nicotinamide-Trytophane Charge-Transfer Interactions: The complexation of nicotinamide-ammonium salts by a macrocyclic receptor molecule bearing tryptophane side chains

J. Behr, J. Lehn, 1980 .

Design of Synthetic Molecular Receptors and Catalysts

J. Behr, J. Lehn, 1981 .

DESIGN OF RIBONUCLEASE MIMICS FOR SEQUENCE SPECIFIC CLEAVAGE OF RNA

V. Vlassov, R. Giegé, G. Zuber, 1996 .

Lipospermine-mediated gene transfer technique into murine cultured cortical cells

J. Behr, B. Sola, C. Staedel, 1997, Journal of Neuroscience Methods.

Gene transfer into intact vertebrate embryos.

J. Behr, B. Demeneix, J. Loeffler, 1991, The International journal of developmental biology.

Gene Regulation Analysis by Lipopolyamine-Mediated DNA Transfer in Primary Neurons

J. Behr, B. Demeneix, J. Loeffler, 1992 .

Eradication of p53-mutated head and neck squamous cell carcinoma (HNSCC) xenografts using nonviral p53 gene therapy and photochemical internalisation (PCI)

F. Guillemin, A. Leroux, J. Merlin, 2005 .

An amphiphilic dendrimer for effective delivery of small interfering RNA and gene silencing in vitro and in vivo.

J. Behr, A. Bolcato-Bellemin, P. Erbacher, 2012, Angewandte Chemie.

Temporal and spatial expression of lipospermine-compacted genes transferred into chick embryos in vivo.

C. Benoist, J. Behr, B. Demeneix, 1994, BioTechniques.

Targeted transfection of human hepatoma cells with a combination of lipospermine and neo-galactolipids

J. Behr, A. Kichler, F. Schuber, 1995 .