J. Peltonen

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Congenital pseudarthrosis of neurofibromatosis type 1: impaired osteoblast differentiation and function and altered NF1 gene expression.

J. Koivunen, L. Messiaen, Hannu-Ville Leskelä, 2009, Bone.

Composition of Neurofibromas, NF1 Expression, and Comparison of Normal and NF1 Haploinsufficient Cells

S. Peltonen, J. Peltonen, 2008 .

New function for NF1 tumor suppressor.

J. Koivunen, J. Karvonen, S. Peltonen, 2000, The Journal of investigative dermatology.

In vivo single-molecule kinetics of activation and subsequent activity of the arabinose promoter

Olli Yli-Harja, Meenakshisundaram Kandhavelu, Andre S. Ribeiro, 2013, Nucleic acids research.

NF1 tumor suppressor in epidermal wound healing with special focus on wound healing in patients with type 1 neurofibromatosis

J. Koivunen, J. Peltonen, H. Ylä-Outinen, 2005, Archives of Dermatological Research.

Breast cancer in neurofibromatosis type 1: overrepresentation of unfavourable prognostic factors

P. Kronqvist, S. Peltonen, J. Peltonen, 2016, British Journal of Cancer.

Collagen Synthesis and Types I, III, IV, and VI Collagens in an Animal Model of Disc Degeneration

T. Takala, H. Vanharanta, J. Peltonen, 1995, Spine.

p38alpha and p38delta mitogen-activated protein kinase isoforms regulate invasion and growth of head and neck squamous carcinoma cells.

J. Westermarck, P. Jaakkola, R. Grenman, 2007, Oncogene.

p38α and p38δ mitogen-activated protein kinase isoforms regulate invasion and growth of head and neck squamous carcinoma cells

J. Westermarck, P. Jaakkola, R. Grenman, 2007, Oncogene.

Cytoskeletal structure in cells harboring two mutations: R133C in NOTCH3 and 5650G>A in mitochondrial DNA.

S. Finnilä, K. Majamaa, J. Peltonen, 2007, Mitochondrion.

Keratinocytes cultured from patients with Hailey–Hailey disease and Darier disease display distinct patterns of calcium regulation

J. Koivunen, S. Peltonen, J. Peltonen, 2005, The British journal of dermatology.

NF1 Tumor Suppressor mRNA Is Targeted to the Cell-Cell Contact Zone in Ca2+-Induced Keratinocyte Differentiation

J. Koivunen, M. Nissinen, S. Peltonen, 2002, Laboratory Investigation.

Psoriasis and altered calcium metabolism: downregulated capacitative calcium influx and defective calcium-mediated cell signaling in cultured psoriatic keratinocytes.

J. Karvonen, M. Nissinen, J. Peltonen, 2000, The Journal of investigative dermatology.

The effects of nerve transection on the endoneurial collagen fibril sheaths

J. Peltonen, M. Röyttä, V. Salonen, 2004, Acta Neuropathologica.

Neurofibromatosis type 1 is not associated with subarachnoid haemorrhage

J. Huttunen, M. von Und Zu Fraunberg, J. Jääskeläinen, 2017, PloS one.

Differential expression of laminin isoforms and beta 4 integrin epitopes in the basement membrane zone of normal human skin and basal cell carcinomas.

J. Uitto, J. Peltonen, S. Sollberg, 1992, The Journal of investigative dermatology.

Follow-Up of Six Patients with Neurofibromatosis 1-Related Osteoporosis Treated with Alendronate for 23 Months

S. Peltonen, J. Peltonen, P. Leinonen, 2014, Calcified Tissue International.

Neurofibromatosis 1-Related Osteopenia Often Progresses to Osteoporosis in 12 Years

T. Kuorilehto, S. Peltonen, J. Peltonen, 2012, Calcified Tissue International.

Differential modulation of basement membrane gene expression in human fibrosarcoma HT-1080 cells by transforming growth factor-beta 1. Enhanced type IV collagen and fibronectin gene expression correlates with altered culture phenotype of the cells.

J. Uitto, V. Kähäri, J. Peltonen, 1991, Laboratory investigation; a journal of technical methods and pathology.

Extracellular matrix of peripheral nerves in diabetes.

J. Peltonen, M. Kalliomäki, P. Muona, 1997, Journal of the peripheral nervous system : JPNS.

Increase of collagen synthesis and deposition in the arachnoid and the dura following subarachnoid hemorrhage in the rat.

S. Finnilä, K. Majamaa, J. Peltonen, 1999, Biochimica et biophysica acta.

Type VI collagen. In situ hybridizations and immunohistochemistry reveal abundant mRNA and protein levels in human neurofibroma, schwannoma and normal peripheral nerve tissues.

R. Timpl, J. Uitto, J. Peltonen, 1990, Laboratory investigation; a journal of technical methods and pathology.

Increased expression of type VI collagen genes in systemic sclerosis.

S. Jimenez, J. Peltonen, L. Kähäri, 1990, Arthritis and rheumatism.

Activation of collagen gene expression in keloids: co-localization of type I and VI collagen and transforming growth factor-beta 1 mRNA.

R. Timpl, J. Uitto, J. Peltonen, 1991, The Journal of investigative dermatology.

Localization of integrin receptors for fibronectin, collagen, and laminin in human skin. Variable expression in basal and squamous cell carcinomas.

H. Gralnick, H. Larjava, J. Uitto, 1989, The Journal of clinical investigation.

Expression of beta 4 integrins in human skin: comparison of epidermal distribution with beta 1-integrin epitopes, and modulation by calcium and vitamin D3 in cultured keratinocytes.

J. Uitto, E. Engvall, J. Peltonen, 1991, The Journal of investigative dermatology.

Upregulation of tumor suppressor protein neurofibromin in normal human wound healing and in vitro evidence for platelet derived growth factor (PDGF) and transforming growth factor-beta1 (TGF-beta1) elicited increase in neurofibromin mRNA steady-state levels in dermal fibroblasts.

J. Peltonen, H. Ylä-Outinen, M. Laato, 1998, The Journal of investigative dermatology.

Activation of Smad signaling enhances collagenase-3 (MMP-13) expression and invasion of head and neck squamous carcinoma cells

S. Leivonen, R. Grenman, R. Ala-aho, 2006, Oncogene.

Keratinocyte Growth Factor Induces Gene Expression Signature Associated with Suppression of Malignant Phenotype of Cutaneous Squamous Carcinoma Cells

R. Grenman, R. Ala-aho, V. Kähäri, 2012, PloS one.

Osteoclasts in neurofibromatosis type 1 display enhanced resorption capacity, aberrant morphology, and resistance to serum deprivation.

T. Kuorilehto, S. Peltonen, J. Peltonen, 2010, Bone.

Hypoxic conditions stimulate the release of B‐type natriuretic peptide from human retinal pigment epithelium cell culture

J. Peltonen, V. Aaltonen, K. Kaarniranta, 2014, Acta ophthalmologica.

Urinary bladder transitional cell carcinogenesis is associated with down-regulation of NF1 tumor suppressor gene in vivo and in vitro.

P. Boström, J. Peltonen, M. Laato, 1999, The American journal of pathology.

Skeletal abnormalities in neurofibromatosis type 1: Approaches to therapeutic options

S. Mundlos, A. Crawford, J. Carey, 2009, American journal of medical genetics. Part A.

Developmental regulation of NF1 tumor suppressor gene in human peripheral nerve

J. Peltonen, H. Ylä-Outinen, S. Karvonen, 1998, Journal of neurocytology.

The development of cutaneous neurofibromas.

E. Jokinen, T. Callens, L. Messiaen, 2011, The American journal of pathology.

Phenotypic characterization of transgenic mice harboring Nf1+/− or Nf1−/− osteoclasts in otherwise Nf1+/+ background

S. Peltonen, J. Peltonen, K. Väänänen, 2012, Journal of cellular biochemistry.

Quantitation of Schwann cells and endoneurial fibroblast-like cells after experimental nerve trauma

J. Peltonen, M. Röyttä, H. Aho, 2004, Acta Neuropathologica.

Tight junction components occludin, ZO‐1, and claudin‐1, ‐4 and ‐5 in active and healing psoriasis

J. Peltonen, K. Pummi, S. Peltonen, 2007, The British journal of dermatology.

Extracellular matrix gene expression by human endothelial and smooth muscle cells.

J. Peltonen, E. Levine, M. Chu, 1991, Matrix.

Hexose sugars differentially alter collagen gene expression and synthesis in fibroblasts derived from granulation tissue, hypertrophic scar and keloid

J. Risteli, J. Peltonen, M. Laato, 2004, Archives of Dermatological Research.

Effect of Sucrose on Collagen Metabolism in Keloid, Hypertrophic Scar, and Granulation Tissue Fibroblast Cultures

J. Risteli, J. Peltonen, M. Laato, 2001, World Journal of Surgery.

Matrix metalloproteinase-19 is expressed by keratinocytes in psoriasis.

J. Peltonen, S. Karvonen, E. Snellman, 2003, Acta dermato-venereologica.

Expression of Fibronectin and Integrins in Cultured Periodontal Ligament Epithelial Cells

H. Larjava, J. Peltonen, D. Brunette, 1992, Journal of dental research.

Increased Matrix Gene Expression by Glucose in Rat Neural Connective Tissue Cells in Culture

J. Uitto, J. Peltonen, S. Jaakkola, 1991, Diabetes.

Perineurial cells coexpress genes encoding interstitial collagens and basement membrane zone components

J. Uitto, J. Peltonen, S. Jaakkola, 1989, The Journal of cell biology.

Collagen gene expression by cultured human skin fibroblasts. Abundant steady-state levels of type VI procollagen messenger RNAs.

J. Uitto, J. Peltonen, S. Jaakkola, 1989, The Journal of clinical investigation.

Arginine depletion in macrophage medium inhibits collagen synthesis by fibroblasts.

H. Larjava, J. Heino, J. Peltonen, 1982, Immunology letters.

Expression of glucose transporter 1 in adult and developing human peripheral nerve

J. Peltonen, S. Jaakkola, V. Salonen, 1993, Diabetologia.

Modulation of Tight Junctions and the Permeability Barrier in Betaine-Treated Keratinocyte Cultures

J. Hakkarainen, V. Kähäri, S. Peltonen, 2021 .

Hailey–Hailey disease and tight junctions: Claudins 1 and 4 are regulated by ATP2C1 gene encoding Ca2+/Mn2+ ATPase SPCA1 in cultured keratinocytes

S. Peltonen, J. Peltonen, M. Mahoney, 2012, Experimental dermatology.

Tight junctions in Hailey-Hailey and Darier's diseases

S. Peltonen, J. Peltonen, P. Hägg, 2009, Dermatology reports.

Immunohistological distribution of the tight junction components ZO‐1 and occludin in regenerating human epidermis

S. Peltonen, J. Peltonen, S. Karvonen, 2003, The British journal of dermatology.

Development of diffuse fasciitis with eosinophilia during L-tryptophan treatment: demonstration of elevated type I collagen gene expression in affected tissues. A clinicopathologic study of four patients.

S. Jimenez, J. Varga, J. Peltonen, 1990, Annals of internal medicine.

Plasticity of integrin expression by nerve-derived connective tissue cells. Human Schwann cells, perineurial cells, and fibroblasts express markedly different patterns of beta 1 integrins during nerve development, neoplasia, and in vitro.

H. Gralnick, J. Uitto, J. Peltonen, 1991, The Journal of clinical investigation.

Collagen, and Laminin in Human Skin Variable Expression in Basal and Squamous Cell Carcinomas

Kenneth M. Yamada, H. Gralnick, H. Larjava, 1989 .

Craniofacial and oral alterations in patients with Neurofibromatosis 1

S. Peltonen, J. Peltonen, V. Visnapuu, 2018, Orphanet Journal of Rare Diseases.

Short mandible, maxilla and cranial base are common in patients with neurofibromatosis 1.

S. Peltonen, J. Peltonen, P. Pirttiniemi, 2011, European journal of oral sciences.

Collagen in human aorta. Changes in the type III/I ratio and concentration of the reducible crosslink, dehydrohydroxylysinonorleucine in ascending aorta from healthy subjects of different age and patients with annulo-aortic ectasia.

J. Peltonen, T. Halme, T. Sims, 1986, Biochimica et biophysica acta.

Isolation, purification and expansion of myelination‐competent, neonatal mouse Schwann cells

M. Nissinen, S. Peltonen, J. Peltonen, 2007, The European journal of neuroscience.

Platelet-derived growth factor isoforms PDGF-AA, -AB and -BB exert specific effects on collagen gene expression and mitotic activity of cultured human wound fibroblasts.

J. Peltonen, M. Laato, J. Niinikoski, 1995, Biochemical and biophysical research communications.

Tight Junction Proteins in Human Schwann Cell Autotypic Junctions

R. Grenman, S. Peltonen, J. Peltonen, 2009, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Protein kinase C alpha/beta inhibitor Go6976 promotes formation of cell junctions and inhibits invasion of urinary bladder carcinoma cells.

J. Koivunen, P. Lehenkari, J. Peltonen, 2004, Cancer research.

Circulating free DNA in the plasma of individuals with neurofibromatosis type 1

S. Peltonen, J. Peltonen, R. Kallionpää, 2021, American journal of medical genetics. Part A.

Expression of claudin‐11 by tumor cells in cutaneous squamous cell carcinoma is dependent on the activity of p38δ

V. Kähäri, S. Peltonen, J. Peltonen, 2017, Experimental dermatology.

A novel component of epidermal cell-matrix and cell-cell contacts: transmembrane protein type XIII collagen.

S. Peltonen, J. Peltonen, H. Ylä-Outinen, 1999, The Journal of investigative dermatology.

In vitro model of bone to facilitate measurement of adhesion forces and super-resolution imaging of osteoclasts

P. Lehenkari, J. Peltonen, Tuomas Näreoja, 2016, Scientific Reports.

The effect of estradiol, testosterone, and human chorionic gonadotropin on the proliferation of Schwann cells with NF1+/− or NF1−/− genotype derived from human cutaneous neurofibromas

S. Peltonen, J. Peltonen, R. Kallionpää, 2017, Molecular and Cellular Biochemistry.

Hyperglycemic glucose concentrations up-regulate the expression of type VI collagen in vitro. Relevance to alterations of peripheral nerves in diabetes mellitus.

J. Uitto, J. Peltonen, L. Pelliniemi, 1993, The American journal of pathology.

Glucose Transporters of Rat Peripheral Nerve: Differential Expression of GLUT1 Gene by Schwann Cells and Perineurial Cells In Vivo and In Vitro

J. Uitto, J. Peltonen, S. Sollberg, 1992, Diabetes.

Molecular and Cellular Basis of Human Cutaneous Neurofibromas and Their Development

S. Peltonen, J. Peltonen, Eeva-Mari Jouhilahti, 2012 .

Tight Junction Proteins and Perineurial Cells in Neurofibromas

S. Peltonen, J. Peltonen, M. Laato, 2006, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Class III β-Tubulin Is a Component of the Mitotic Spindle in Multiple Cell Types

S. Peltonen, J. Peltonen, Eeva-Mari Jouhilahti, 2008, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

HCR, a candidate gene for psoriasis, is expressed differently in psoriasis and other hyperproliferative skin disorders and is downregulated by interferon-gamma in keratinocytes.

J. Kere, J. Peltonen, S. Karvonen, 2003, The Journal of investigative dermatology.

Neurofibromatosis type 1 tumour suppressor gene expression is deficient in psoriatic skin in vivo and in vitro: a potential link to increased Ras activity

J. Koivunen, M. Nissinen, J. Peltonen, 2004, The British journal of dermatology.

Cellular differentiation and expression of matrix genes in type 1 neurofibromatosis.

M. Lebwohl, J. Uitto, J. Peltonen, 1988, Laboratory investigation; a journal of technical methods and pathology.

Association Between Invasive Lobular Breast Cancer and Mutations in the Mismatch Repair Gene MSH6.

D. Evans, J. Peltonen, S. Howell, 2019, JAMA oncology.

Gene panel testing for breast cancer should not be used to confirm syndromic gene associations

D. Evans, J. Peltonen, I. Frayling, 2018, npj Genomic Medicine.

Gene panel testing for breast cancer should not be used to confirm associations with syndromic genes in particular for NF1 pathogenic variants Running Head: Panel testing for syndromic gene cancer associations

D. Evans, J. Peltonen, I. Frayling, 2019 .

Panel testing for syndromic gene cancer associations

D. Evans, J. Peltonen, I. Frayling, 2018 .

Incidence and mortality of neurofibromatosis: a total population study in Finland.

T. Vahlberg, J. Vahtera, S. Peltonen, 2015, The Journal of investigative dermatology.

Elevated expression of beta 1 and beta 2 integrins, intercellular adhesion molecule 1, and endothelial leukocyte adhesion molecule 1 in the skin of patients with systemic sclerosis of recent onset.

S. Jimenez, J. Uitto, J. Peltonen, 1992, Arthritis and rheumatism.

Distribution of different collagen types and fibronectin in neurofibromatosis tumours.

J. Foidart, J. Peltonen, A. Vaheri, 2009, Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology.

Laminin in traumatized peripheral nerve: Basement membrane changes during degeneration and regeneration

J. Peltonen, M. Röyttä, I. Virtanen, 1987, Journal of neurocytology.

Cytoskeletal structure of myoblasts with the mitochondrial DNA 3243A-->G mutation and of osteosarcoma cells with respiratory chain deficiency.

K. Majamaa, I. Hassinen, J. Peltonen, 2002, Cell motility and the cytoskeleton.

Mast Cells in Human Cutaneous Neurofibromas: Density, Subtypes, and Association with Clinical Features in Neurofibromatosis 1

S. Peltonen, J. Peltonen, E. Fazeli, 2021, Dermatology.

The expression of α6 and β4 integrin genes are differentially regulated byall-trans-retinoic acid (RA) in cultured human keratinocytes

J. Peltonen, L. Laurikainen, T. Carey, 1996, Archives of Dermatological Research.

Neurofibromatosis type 1 of the child increases birth weight

T. Vahlberg, S. Peltonen, J. Peltonen, 2019, American journal of medical genetics. Part A.

Protein Kinase C Family

J. Peltonen, V. Aaltonen, 2014 .

Recent developments in neurofibromatoses and RASopathies: Management, diagnosis and current and future therapeutic avenues

M. Patton, S. Huson, M. Vikkula, 2015, American journal of medical genetics. Part A.

Reevaluation of the normal epidermal calcium gradient, and analysis of calcium levels and ATP receptors in Hailey-Hailey and Darier epidermis.

S. Peltonen, J. Peltonen, T. Korkiamäki, 2009, The Journal of investigative dermatology.

Reversible endoneurial changes after nerve injury

J. Peltonen, M. Röyttä, V. Salonen, 2004, Acta Neuropathologica.

Perineurial cells in culture. An immunocytochemical and electron microscopic study.

J. Peltonen, L. Pelliniemi, I. Virtanen, 1987, Laboratory investigation; a journal of technical methods and pathology.

Basement membranes during development of human nerve: Schwann cells and perineurial cells display marked changes in their expression profiles for laminin subunits and β1 and β4 integrins

J. Uitto, J. Peltonen, S. Jaakkola, 1993, Journal of neurocytology.

Evaluation of transforming growth factor beta and type I procollagen gene expression in fibrotic skin diseases by in situ hybridization.

S. Jimenez, J. Uitto, V. Kähäri, 1990, The Journal of investigative dermatology.

Tight Junction Proteins ZO-1, Occludin, and Claudins in Developing and Adult Human Perineurium

R. Grenman, S. Peltonen, J. Peltonen, 2004, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Elevated expression of the genes for transforming growth factor-beta 1 and type VI collagen in diffuse fasciitis associated with the eosinophilia-myalgia syndrome.

S. Jimenez, J. Varga, J. Peltonen, 1991, The Journal of investigative dermatology.

Analysis of structural cell proteins by isoelectric focusing in zwitterionic agarose gel thin layers

J. Peltonen, A. Salmi, T. Kouri, 1983 .

Isoelectric focusing of macrophage culture media and the effect of the fractions on the synthesis of DNA and collagen by fibroblasts.

J. Peltonen, E. Kulonen, M. Jalkanen, 1979, Acta pathologica et microbiologica Scandinavica. Section C, Immunology.

Congenital anomalies in neurofibromatosis 1: a retrospective register-based total population study

T. Vahlberg, S. Peltonen, J. Peltonen, 2018, Orphanet Journal of Rare Diseases.

Occult neurofibroma and increased S100 protein in the skin of patients with neurofibromatosis type 1: new insight to the etiopathomechanism of neurofibromas.

J. Peltonen, H. Ylä-Outinen, S. Karvonen, 2000, Archives of dermatology.

The rare disease neurofibromatosis 1 as a source of hereditary economic inequality: Evidence from Finland.

S. Peltonen, J. Peltonen, E. Johansson, 2021, Genetics in medicine : official journal of the American College of Medical Genetics.

Osteoclasts derived from patients with neurofibromatosis 1 (NF1) display insensitivity to bisphosphonates in vitro.

S. Peltonen, J. Peltonen, K. Väänänen, 2012, Bone.

Neurofibromatosis 1-Related Osteopenia Often Progresses to Osteoporosis in 12 Years

T. Kuorilehto, S. Peltonen, J. Peltonen, 2012, Calcified Tissue International.

Independent NF1 mutations in two large families with spinal neurofibromatosis

J. Koivunen, I. Vandenbroucke, T. Callens, 2003, Journal of medical genetics.

Expression of laminin and collagen genes by cells cultured from developing human sciatic nerves.

S. Peltonen, J. Peltonen, A. Björkstrand, 1996, Journal of the peripheral nervous system : JPNS.

Expression of laminin isoforms by peripheral nerve-derived connective tissue cells in culture. Comparison with epitope distribution in normal human nerve and neural tumors in vivo.

J. Uitto, E. Engvall, J. Peltonen, 1993, Laboratory investigation; a journal of technical methods and pathology.

Fibronectin gene expression by epithelial tumor cells in basal cell carcinoma: an immunocytochemical and in situ hybridization study.

J. Uitto, J. Peltonen, I. Virtanen, 1988, The Journal of investigative dermatology.

Human laminin: cloning and sequence analysis of cDNAs encoding A, B1 and B2 chains, and expression of the corresponding genes in human skin and cultured cells.

T. Sasaki, H. Kuivaniemi, J. Peltonen, 1989, Laboratory investigation; a journal of technical methods and pathology.

Decreased bone mineral density and content in neurofibromatosis type 1: Lowest local values are located in the load-carrying parts of the body

R. Bloigu, T. Kuorilehto, J. Peltonen, 2005, Osteoporosis International.

NF1 Tumor Suppressor Protein and mRNA in Skeletal Tissues of Developing and Adult Normal Mouse and NF1‐Deficient Embryos

J. Koivunen, T. Kuorilehto, M. Nissinen, 2004, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Vasculopathy in two cases of NF1-related congenital pseudarthrosis.

Hannu-Ville Leskelä, T. Kuorilehto, M. Nissinen, 2006, Pathology, research and practice.

NF1 Gene Expression in Mouse Fracture Healing and in Experimental Rat Pseudarthrosis

T. Kuorilehto, M. Nissinen, J. Peltonen, 2006, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

The effect of extracellular calcium concentration on calcium-mediated cell signaling in NF1 tumor suppressor-deficient keratinocytes

J. Koivunen, J. Peltonen, H. Ylä-Outinen, 2005, Archives of Dermatological Research.

Epidermal tight junctions: ZO-1 and occludin are expressed in mature, developing, and affected skin and in vitro differentiating keratinocytes.

S. Peltonen, J. Peltonen, S. Karvonen, 2001, The Journal of investigative dermatology.

Cultured neurofibromatosis tumor fibroblasts lack beta-adrenergic receptors.

T. Kaila, J. Peltonen, R. Penttinen, 1988, Neurofibromatosis.

Endoneurial fibrosis following nerve transection

J. Peltonen, M. Lehto, A. Vaheri, 1985, Acta Neuropathologica.

Collagen synthesis in cells cultured from v. Recklinghausen's neurofibromatosis

J. Peltonen, R. Penttinen, T. Vihersaari, 2004, Acta Neuropathologica.

Schwann cells and collagen synthesis in taxol-treated nerve crush. An electron microscopic study.

V. Vuorinen, J. Peltonen, M. Röyttä, 1988, Collagen and related research.

Collagens in Neurofibromas and Neurofibroma Cell Cultures

H. Larjava, J. Peltonen, R. Penttinen, 1986, Annals of the New York Academy of Sciences.

Novel function for beta 1 integrins in keratinocyte cell-cell interactions

H. Gralnick, H. Larjava, J. Uitto, 1990, The Journal of cell biology.

Type IV and V collagens in von Recklinghausen’s neurofibromas

J. Foidart, J. Peltonen, H. Aho, 1984, Virchows Archiv. B, Cell pathology including molecular pathology.

Protein kinase C (PKC) family in cancer progression.

J. Koivunen, J. Peltonen, V. Aaltonen, 2006, Cancer letters.

Intestinal tumors in neurofibromatosis 1 with special reference to fatal gastrointestinal stromal tumors (GIST)

S. Peltonen, J. Peltonen, H. Ylä-Outinen, 2019, Molecular genetics & genomic medicine.

Distinctive Cancer Associations in Patients With Neurofibromatosis Type 1.

S. Peltonen, J. Peltonen, V. Riccardi, 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

THE ROOTS OF NEUROFIBROMAS IN NEUROFIBROMATOSIS 1

J. Peltonen, 2012 .

The pathoetiology of neurofibromatosis 1.

S. Peltonen, J. Peltonen, A. Heape, 2011, The American journal of pathology.

p53-regulated long non-coding RNA PRECSIT promotes progression of cutaneous squamous cell carcinoma via STAT3 signaling.

V. Kähäri, S. Peltonen, J. Peltonen, 2019, The American journal of pathology.

Expression Profiles and Clinical Correlations of Degradome Components in the Tumor Microenvironment of Head and Neck Squamous Cell Carcinoma

Y. Okada, R. Ala-aho, V. Kähäri, 2010, Clinical Cancer Research.

Neurofibromatosis type 1 gene mutation analysis using sequence capture and high-throughput sequencing.

J. Soini, S. Peltonen, J. Peltonen, 2014, Acta dermato-venereologica.

Cutaneous neuro ﬁ bromas Current clinical and pathologic issues

Douglas C. Miller, A. Stemmer-Rachamimov, B. Korf, 2022 .

Cutaneous neurofibromas

Douglas C. Miller, A. Stemmer-Rachamimov, B. Korf, 2018, Neurology.

Prevalence of neurofibromatosis type 1 in the Finnish population

S. Peltonen, J. Peltonen, M. Pöyhönen, 2017, Genetics in Medicine.

The pregnancy in neurofibromatosis 1: A retrospective register‐based total population study

T. Vahlberg, S. Peltonen, J. Peltonen, 2017, American journal of medical genetics. Part A.

Haploinsufficiency of the NF1 gene is associated with protection against diabetes

K. Auranen, S. Peltonen, J. Peltonen, 2020, Journal of Medical Genetics.

Compound heterozygous desmoplakin mutations result in a phenotype with a combination of myocardial, skin, hair, and enamel abnormalities.

J. Uitto, S. Peltonen, J. Peltonen, 2010, The Journal of investigative dermatology.

Pediatric malignancies in neurofibromatosis type 1: A population‐based cohort study

S. Peltonen, J. Peltonen, M. Pöyhönen, 2019, International journal of cancer.

Breast cancer risk in neurofibromatosis type 1 is a function of the type of NF1 gene mutation: a new genotype-phenotype correlation

D. Baralle, P. Summerour, D. Eccles, 2018, Journal of Medical Genetics.

Altered calcium-mediated cell signaling in keratinocytes cultured from patients with neurofibromatosis type 1.

J. Koivunen, J. Peltonen, H. Ylä-Outinen, 2002, The American journal of pathology.

Ultrastructural localization of NF1 tumor suppressor protein in human skin

J. Koivunen, T. Kuorilehto, S. Peltonen, 2002, Archives of Dermatological Research.

Oscillation and rapid changes of NF1 mRNA steady-state levels in cultured human keratinocytes

J. Peltonen, H. Ylä-Outinen, K. Pummi, 2000, Archives of Dermatological Research.

A controlled register‐based study of 460 neurofibromatosis 1 patients: Increased fracture risk in children and adults over 41 years of age

E. Jokinen, T. Kuorilehto, S. Peltonen, 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Lesional psoriatic epidermis displays reduced neurofibromin immunoreactivity.

J. Karvonen, J. Peltonen, H. Ylä-Outinen, 1995, The Journal of investigative dermatology.

Neurofibromin: expression by normal human keratinocytes in vivo and in vitro and in epidermal malignancies.

S. Peltonen, J. Peltonen, H. Ylä-Outinen, 1995, Laboratory investigation; a journal of technical methods and pathology.

Functional expression of NF1 tumor suppressor protein: association with keratin intermediate filaments during the early development of human epidermis

J. Koivunen, S. Peltonen, J. Peltonen, 2002, BMC dermatology.

Protein Kinase C α/β Inhibitor Go6976 Promotes Formation of Cell Junctions and Inhibits Invasion of Urinary Bladder Carcinoma Cells

J. Koivunen, P. Lehenkari, J. Peltonen, 2004, Cancer Research.

Protein Kinase C / Inhibitor Go 6976 Promotes Formation of Cell Junctions and Inhibits Invasion of Urinary Bladder Carcinoma Cells

J. Koivunen, P. Lehenkari, J. Peltonen, 2004 .

Differential effects of hexoses and sucrose, and platelet-derived growth factor isoforms on cyclooxygenase-1 and -2 mRNA expression in keloid, hypertrophic scar and granulation tissue fibroblasts

J. Peltonen, M. Laato, J. Kössi, 2001, Archives of Dermatological Research.

Effects of Hexose Sugars: Glucose, Fructose, Galactose and Mannose on Wound Healing in the Rat

T. Ekfors, J. Peltonen, M. Laato, 1999, European Surgical Research.

Density and function of actin-microdomains in healthy and NF1 deficient osteoclasts revealed by the combined use of atomic force and stimulated emission depletion microscopy

J. Eriksson, J. Peltonen, K. Vienola, 2019, Journal of Physics D: Applied Physics.

Neurofibromatosis tumor and skin cells in culture

J. Peltonen, U. Rinne, R. Penttinen, 2004, Acta Neuropathologica.

Periapical cemental dysplasia is common in women with NF1.

S. Peltonen, J. Peltonen, K. Väänänen, 2007, European journal of medical genetics.

Radiographic findings in the jaws of patients with neurofibromatosis 1.

S. Peltonen, J. Peltonen, V. Visnapuu, 2012, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

Speech characteristics in neurofibromatosis type 1

O. Aaltonen, S. Peltonen, J. Peltonen, 2010, American journal of medical genetics. Part A.

Serpin peptidase inhibitor clade A member 1 (SerpinA1) is a novel biomarker for progression of cutaneous squamous cell carcinoma.

R. Ala-aho, V. Kähäri, J. Peltonen, 2011, The American journal of pathology.

Normal and hypertrophic scars: quantification and localization of messenger RNAs for type I, III and VI collagens

J. Peltonen, M. Laato, H. Kalimo, 1994, The British journal of dermatology.

Long Noncoding RNA PICSAR Promotes Growth of Cutaneous Squamous Cell Carcinoma by Regulating ERK1/2 Activity.

V. Kähäri, S. Peltonen, J. Peltonen, 2016, The Journal of investigative dermatology.

Breast cancer in neurofibromatosis 1: survival and risk of contralateral breast cancer in a five country cohort study

D. Evans, S. Peltonen, J. Peltonen, 2019, Genetics in Medicine.

NEUROFIBROMATOSIS 1 (NF1)

J. Peltonen, E. Heervä, Eetu Heervä, 2013 .

Signaling pathways in human osteoclasts differentiation: ERK1/2 as a key player

V. Kähäri, S. Peltonen, J. Peltonen, 2021, Molecular Biology Reports.

Neurofibromatosis type 1 (NF1) gene: Beyond café au lait spots and dermal neurofibromas

S. Peltonen, J. Peltonen, R. Kallionpää, 2017, Experimental dermatology.

Dental age in patients with neurofibromatosis 1.

S. Peltonen, J. Peltonen, V. Visnapuu, 2012, European journal of oral sciences.

Oral soft tissue alterations in patients with neurofibromatosis

S. Peltonen, J. Peltonen, T. Soukka, 2011, Clinical Oral Investigations.

Oral soft tissue alterations in patients with neurofibromatosis

S. Peltonen, J. Peltonen, T. Soukka, 2012, Clinical Oral Investigations.

Neurofibromatosis 1 and dental caries

S. Peltonen, J. Peltonen, V. Visnapuu, 2011, Clinical Oral Investigations.

A fibroblast cell line cultured from a hypertrophic scar displays selective downregulation of collagen gene expression: barely detectable messenger RNA levels of the proα1(III) chain of type III collagen

J. Peltonen, M. Laato, A. Oikarinen, 2004, Archives of Dermatological Research.

Expression profiles of cell-cell and cell-matrix junction proteins in developing human epidermis

S. Peltonen, J. Peltonen, M. Hentula, 2001, Archives of Dermatological Research.

Barriers of the peripheral nerve

S. Peltonen, J. Peltonen, Juha Peltonen, 2013, Tissue barriers.

Restricted Distribution of mRNAs Encoding a Sarcoplasmic Reticulum or Transverse Tubule Protein in Skeletal Myofibers

M. Nissinen, J. Peltonen, K. Metsikkö, 2005, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Complement factor H: a biomarker for progression of cutaneous squamous cell carcinoma.

S. Meri, R. Ala-aho, V. Kähäri, 2014, The Journal of investigative dermatology.

A rapid assay to measure collagen synthesis in cell cultures.

M. Tammi, J. Peltonen, R. Penttinen, 1980, Journal of biochemical and biophysical methods.

Association of Catechol-O-methyltransferase polymorphism Val158Met and mammographic density: A meta-analysis.

J. Peltonen, R. Kallionpää, E. Uusitalo, 2017, Gene.

PKCα/β I Inhibitor Go6976 Induces Dephosphorylation of Constitutively Hyperphosphorylated Rb and G1 Arrest in T24 Cells

J. Peltonen, V. Aaltonen, 2010 .

Expression of type I, III, and VI collagen mRNAs in experimentally injured porcine intervertebral disc.

H. Vanharanta, J. Peltonen, S. Holm, 1994, Connective tissue research.

PKC inhibitor Go6976 induces mitosis and enhances doxorubicin-paclitaxel cytotoxicity in urinary bladder carcinoma cells.

J. Koivunen, J. Peltonen, M. Laato, 2007, Cancer letters.

Complement factor I promotes progression of cutaneous squamous cell carcinoma.

S. Meri, R. Ala-aho, V. Kähäri, 2015, The Journal of investigative dermatology.

Tumor cell-specific AIM2 regulates growth and invasion of cutaneous squamous cell carcinoma

V. Kähäri, S. Peltonen, J. Peltonen, 2017, Oncotarget.

Collagenase 3 (matrix metalloproteinase 13) gene expression by HaCaT keratinocytes is enhanced by tumor necrosis factor alpha and transforming growth factor beta.

C. López-Otín, J. Heino, J. Westermarck, 1997, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

Novel Function for Integrins in Keratinocyte Cell-Cell Interactions

Kenneth M. Yamada, H. Gralnick, H. Larjava, 2002 .

Neurofibromatosis Type 1 Gene Mutation Analysis Using Sequence Capture and High-throughput Sequencing Uusitalo

J. Soini, S. Peltonen, J. Peltonen, 2022 .

Selective modulation of collagen gene expression by different isoforms of platelet-derived growth factor in experimental wound healing

J. Peltonen, M. Laato, J. Niinikoski, 1996, Cell and Tissue Research.

Diversity of actin architecture in human osteoclasts: network of curved and branched actin supporting cell shape and intercellular micrometer-level tubes

S. Peltonen, J. Peltonen, Tuomas Näreoja, 2017, Molecular and Cellular Biochemistry.

EphB2 Promotes Progression of Cutaneous Squamous Cell Carcinoma.

R. Ala-aho, V. Kähäri, S. Peltonen, 2015, Journal of Investigative Dermatology.

Plasminogen activators and their inhibitor gene expression in cutaneous NF1-related neurofibromas

J. Peltonen, A. Vaheri, V. Sirén, 2006, Archives of Dermatological Research.

Increased risk for dementia in neurofibromatosis type 1

K. Auranen, J. Rinne, S. Peltonen, 2021, Genetics in Medicine.

Endothelial cell growth factor and heparin regulate collagen gene expression in keloid fibroblasts.

J. Peltonen, E. Tan, 1991, The Biochemical journal.

Combined use of in situ hybridization and unlabeled antibody peroxidase anti-peroxidase methods: simultaneous detection of type I procollagen mRNAs and factor VIII-related antigen epitopes in keloid tissue.

J. Uitto, J. Peltonen, S. Sollberg, 1991, Laboratory investigation; a journal of technical methods and pathology.

Segmental neurofibromatosis: immunocytochemical analysis of cutaneous lesions.

J. Uitto, J. Karvonen, J. Peltonen, 1990, Journal of the American Academy of Dermatology.

Complement Component C3 and Complement Factor B Promote Growth of Cutaneous Squamous Cell Carcinoma.

S. Meri, V. Kähäri, S. Peltonen, 2017, The American journal of pathology.

TUMORIGENESIS AND NEOPLASTIC PROGRESSION Complement Component C 3 and Complement Factor B Promote Growth of Cutaneous Squamous Cell Carcinoma

S. Meri, V. Kähäri, S. Peltonen, 2022 .

Tumour‐cell‐derived complement components C1r and C1s promote growth of cutaneous squamous cell carcinoma†

S. Meri, V. Kähäri, S. Peltonen, 2019, The British journal of dermatology.

p38δ mitogen-activated protein kinase regulates the expression of tight junction protein ZO-1 in differentiating human epidermal keratinocytes

V. Kähäri, S. Peltonen, J. Peltonen, 2014, Archives of Dermatological Research.

Myelination in mouse dorsal root ganglion/Schwann cell cocultures

Marja Nissinen, M. Nissinen, S. Peltonen, 2008, Molecular and Cellular Neuroscience.

Tumour necrosis factor-alpha selectivity modulates expression of collagen genes in rat granulation tissue.

J. Heino, J. Peltonen, M. Laato, 1997, The European journal of surgery = Acta chirurgica.

Expression and distribution of two alternatively spliced transcripts from the chicken α2(VI) collagen gene

E. Vuorio, J. Peltonen, B. Odermatt, 1996, Journal of cellular biochemistry.

Prevalence of neurofibromatosis type 1 in the Finnish population

S. Peltonen, J. Peltonen, M. Pöyhönen, 2018, Genetics in Medicine.

Desmosomes in Developing Human Epidermis

S. Peltonen, J. Peltonen, L. Raiko, 2010, Dermatology research and practice.

Follow-Up of Six Patients with Neurofibromatosis 1-Related Osteoporosis Treated with Alendronate for 23 Months

S. Peltonen, J. Peltonen, P. Leinonen, 2014, Calcified Tissue International.

Connective tissue metabolism in diabetic peripheral nerves.

J. Peltonen, P. Muona, 1994, Annals of medicine.

The distribution of collagen types I, III, and IV in normal and malignant colorectal mucosa.

Y. Collan, J. Peltonen, M. Laato, 2003, The European journal of surgery = Acta chirurgica.

Effects of glucose on collagen mRNA levels and collagen secretion in EAhy 926 endothelial cell line.

J. Risteli, J. Peltonen, H. Ylä-Outinen, 2001, Annales chirurgiae et gynaecologiae. Supplementum.

Type 1 neurofibromatosis: selective expression of extracellular matrix genes by Schwann cells, perineurial cells, and fibroblasts in mixed cultures.

J. Uitto, J. Peltonen, S. Jaakkola, 1989, The Journal of clinical investigation.

Diabetes induces the formation of large diameter collagen fibrils in the sciatic nerves of BB rats.

J. Peltonen, S. Jaakkola, V. Salonen, 1989, Matrix.

[24] In Situ hybridization and immunodetection techniques for simultaneous localization of messenger RNAs and protein epitopes in tissue sections and cultured cells

J. Uitto, J. Peltonen, S. Jaakkola, 1991 .

Laminin-5 Expression Is Independent of the Injury and the Microenvironment During Reepithelialization of Wounds

H. Larjava, T. Salo, J. Peltonen, 1998, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Expression of extracellular matrix genes by cultured human cells: localization of messenger RNAs and antigenic epitopes.

J. Uitto, J. Peltonen, S. Jaakkola, 1989, Analytical biochemistry.

Gene panel testing for breast cancer should not be used to confirm syndromic gene associations

D. Evans, J. Peltonen, I. Frayling, 2018, npj Genomic Medicine.

Heterogeneity of Cellular Proliferation within Transitional Cell Carcinoma: Correlation of Protein Kinase C Alpha/betal Expression and Activity

J. Koivunen, J. Peltonen, M. Laato, 2006, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

An approach to comprehensive genome and proteome expression analyses in Schwann cells and neurons during peripheral nerve myelin formation

S. Ohlmeier, S. Peltonen, J. Peltonen, 2016, Journal of neurochemistry.

A method for bleaching pulp with ozone

J. Peltonen, H.‐O. Henricson, T. Laxen, 1990 .

Suprabasal expression of epidermal alpha 2 beta 1 and alpha 3 beta 1 integrins in skin treated with topical retinoic acid.

J. Heino, J. Westermarck, V. Kähäri, 1998, The British journal of dermatology.

The effect of estradiol, testosterone, and human chorionic gonadotropin on the proliferation of Schwann cells with NF1+/− or NF1−/− genotype derived from human cutaneous neurofibromas

S. Peltonen, J. Peltonen, R. Kallionpää, 2018, Molecular and Cellular Biochemistry.

Neurofibromatosis tumor and skin cells in culture

J. Peltonen, K. Näntö-Salonen, I. Virtanen, 2004, Acta Neuropathologica.

An intact actin-containing cytoskeleton is required for capacitative calcium entry, but not for ATP-induced calcium-mediated cell signaling in cultured human keratinocytes.

J. Koivunen, J. Peltonen, H. Ylä-Outinen, 2003, Medical science monitor : international medical journal of experimental and clinical research.

Adherent cells from rheumatoid synovia: identity of HLA-DR positive stellate cells.

J. Peltonen, T. Kouri, M. Viander, 1987, Annals of the rheumatic diseases.

The effects of interleukin-1 and prostaglandin E2 on accumulation of collagen and steady-state levels of proα1(I) collagen messenger RNA in experimental granulation tissue in rats

J. Heino, J. Peltonen, K. Rapala, 1997, Archives of Dermatological Research.

EphB2 Promotes Progression of Cutaneous Squamous Cell Carcinoma.

V. Kähäri, S. Peltonen, J. Peltonen, 2015, The Journal of investigative dermatology.

Distinctive Cancer Associations in Patients With Neurofibromatosis Type 1.

S. Peltonen, J. Peltonen, V. Riccardi, 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.