C. Rudolph

发表

Transcription-dependent spatial arrangements of CFTR and adjacent genes in human cell nuclei

Joseph Rosenecker, Luka A. Clarke, Margarida D. Amaral, 2004, The Journal of cell biology.

Dynamic mRNA polyplexes benefit from bioreducible cleavage sites for in vitro and in vivo transfer.

C. Rudolph, E. Wagner, A. Levačić, 2021, Journal of controlled release : official journal of the Controlled Release Society.

Targeting of the prostacyclin specific IP1 receptor in lungs with molecular conjugates comprising prostaglandin I2 analogues.

C. Rudolph, U. Rothbauer, J. Geiger, 2010, Biomaterials.

Efficient, specific and targeted delivery of genes to the lung.

C. Rudolph, J. Geiger, M. Aneja, 2010, Therapeutic delivery.

Characterization of tailor-made copolymers of oligo(ethylene glycol) methyl ether methacrylate and N,N-dimethylaminoethyl methacrylate as nonviral gene transfer agents: influence of macromolecular structure on gene vector particle properties and transfection efficiency.

H. Stark, M. Golas, B. Sander, 2010, Biomacromolecules.

Self-assembly of ternary insulin-polyethylenimine (PEI)-DNA nanoparticles for enhanced gene delivery and expression in alveolar epithelial cells.

H. Stark, M. Golas, B. Sander, 2009, Biomacromolecules.

Targeting of the beta(2)-adrenoceptor increases nonviral gene delivery to pulmonary epithelial cells in vitro and lungs in vivo.

C. Rudolph, J. Geiger, M. Aneja, 2009, Journal of controlled release : official journal of the Controlled Release Society.

Characterization of lactoferrin as a targeting ligand for nonviral gene delivery to airway epithelial cells.

C. Rudolph, C. Maucksch, Markus Elfinger, 2007, Biomaterials.

Interaction of polyamine gene vectors with RNA leads to the dissociation of plasmid DNA‐carrier complexes

J. Rosenecker, C. Rudolph, Katharina von Gersdorff, 2006, The journal of gene medicine.

Uronic acids functionalized polyethyleneimine (PEI)-polyethyleneglycol (PEG)-graft-copolymers as novel synthetic gene carriers.

J. Rosenecker, C. Rudolph, H. Möhwald, 2006, Biomaterials.

Advances in magnetofection—magnetically guided nucleic acid delivery

T. Brill, C. Rudolph, C. Plank, 2005 .

Gene delivery to respiratory epithelial cells by magnetofection

J. Rosenecker, C. Rudolph, C. Plank, 2004, The journal of gene medicine.

Insights into the mechanism of magnetofection using PEI‐based magnetofectins for gene transfer

J. Rosenecker, C. Rudolph, C. Plank, 2004, The journal of gene medicine.

Enhancing and targeting nucleic acid delivery by magnetic force

Joseph Rosenecker, Carsten Rudolph, Christian Plank, 2003, Expert opinion on biological therapy.

In vivo gene delivery to the lung using polyethylenimine and fractured polyamidoamine dendrimers

R. Müller, J. Rosenecker, C. Rudolph, 2000, The journal of gene medicine.

A novel transfecting peptide comprising a tetrameric nuclear localization sequence

J. Rosenecker, C. Rudolph, C. Plank, 2003, Journal of Molecular Medicine.

PEGylation Improves Nanoparticle Formation and Transfection Efficiency of Messenger RNA

J. Rosenecker, C. Rudolph, J. Lutz, 2011, Pharmaceutical Research.

Quantification of magnetic nanoparticle concentration in pig lung tissue after magnetic aerosol drug targeting by magnetorelaxometry

Frank Wiekhorst, Uwe Steinhoff, Dietmar Eberbeck, 2009 .

Human cellular CYBA UTR sequences increase mRNA translation without affecting the half-life of recombinant RNA transcripts

C. Rudolph, E. Balmayor, O. Mykhaylyk, 2016, Scientific Reports.

Stability analysis of chemically modified mRNA using micropattern-based single-cell arrays.

C. Rudolph, C. Leonhardt, J. Rädler, 2015, Lab on a chip.

Maximizing the Translational Yield of mRNA Therapeutics by Minimizing 5'-UTRs.

C. Rudolph, C. Plank, J. Geiger, 2019, Tissue engineering. Part A.

Segmented poly(A) tails significantly reduce recombination of plasmid DNA without affecting mRNA translation efficiency or half-life

C. Rudolph, C. Plank, J. Geiger, 2019, RNA.

Conversion of adult human fibroblasts into neural precursor cells using chemically modified mRNA

C. Rudolph, J. Geiger, Kevin Lee, 2018, Heliyon.

Efficient ex vivo delivery of chemically modified messenger RNA using lipofection and magnetofection.

C. Rudolph, O. Mykhaylyk, C. Plank, 2017, Biochemical and biophysical research communications.

Transcript-activated collagen matrix as sustained mRNA delivery system for bone regeneration.

C. Rudolph, M. Utzinger, C. Plank, 2016, Journal of controlled release : official journal of the Controlled Release Society.

Aerosolized nanogram quantities of plasmid DNA mediate highly efficient gene delivery to mouse airway epithelium.

H. Stark, M. Golas, B. Sander, 2005, Molecular therapy : the journal of the American Society of Gene Therapy.

Targeted delivery of magnetic aerosol droplets to the lung

Bernhard Gleich, Thomas Weyh, Lutz Trahms, 2007, Nature Nanotechnology.

Localized nucleic acid delivery to living cells using nanobiotechnology approaches

C. Rudolph, B. Gansbacher, C. Plank, 2004, 4th IEEE Conference on Nanotechnology, 2004..

Preclinical Evaluation of a Novel TALEN Targeting CCR5 Confirms Efficacy and Safety in Conferring Resistance to HIV‐1 Infection

A. Juillerat, P. Duchateau, K. Metzner, 2020, Biotechnology journal.

Jet nebulization of PEI/DNA polyplexes: physical stability and in vitro gene delivery efficiency

R. Müller, J. Rosenecker, C. Rudolph, 2002, The journal of gene medicine.

Efficient Non-viral Gene Delivery into Human Hematopoietic Stem Cells by Minicircle Sleeping Beauty Transposon Vectors

Z. Izsvák, C. Rudolph, J. Bueren, 2018, Molecular therapy : the journal of the American Society of Gene Therapy.

Phage phiC31 integrase‐mediated genomic integration and long‐term gene expression in the lung after nonviral gene delivery

C. Rudolph, M. Aneja, Rabea Imker, 2007, The journal of gene medicine.

Gene therapy for cystic fibrosis lung disease: current status and future perspectives.

J. Rosenecker, C. Rudolph, S. Huth, 2006, Current opinion in molecular therapeutics.

Exploring Cytotoxic mRNAs as a Novel Class of Anti-cancer Biotherapeutics

C. Rudolph, E. Wagner, Anita Jarzębińska, 2017, Molecular therapy. Methods & clinical development.

Repeated siRNA application is a precondition for successful mRNA gammaENaC knockdown in the murine airways.

J. Rosenecker, C. Rudolph, M. Kormann, 2010, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Adeno-associated virus serotype 9-mediated pulmonary transgene expression: effect of mouse strain, animal gender and lung inflammation

C. Rudolph, M. Aneja, C. Pfeifer, 2011, Gene Therapy.

Cell type differences in activity of the Streptomyces bacteriophage ϕC31 integrase

J. Rosenecker, C. Rudolph, M. Aneja, 2008, Nucleic acids research.

Optimization of Streptomyces bacteriophage ϕC31 integrase system to prevent post integrative gene silencing in pulmonary type II cells

C. Rudolph, M. Kormann, J. Geiger, 2009, Experimental & Molecular Medicine.

cmRNA/lipoplex encapsulation in PLGA microspheres enables transfection via calcium phosphate cement (CPC)/PLGA composites

G. Winter, C. Rudolph, Anita Jarzębińska, 2017, Journal of controlled release : official journal of the Controlled Release Society.

Respiration triggered magnetic drug targeting in the lungs

C. Rudolph, C. Dahmani, T. Weyh, 2009, 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

Breath Synchronous Magnetic Drug Targeting in the Lungs

Stefan Götz, C. Rudolph, C. Dahmani, 2009 .

Vectors for pulmonary gene therapy.

C. Rudolph, J. Geiger, M. Aneja, 2010, International journal of pharmaceutics.

Methodological optimization of polyethylenimine (PEI)‐based gene delivery to the lungs of mice via aerosol application

J. Rosenecker, C. Rudolph, C. Plank, 2005, The journal of gene medicine.

Airway surface liquid contains endogenous DNase activity which can be activated by exogenous magnesium

J. Rosenecker, C. Rudolph, S. Naundorf, 2009, European journal of medical research.

Modified mRNA for BMP-2 in Combination with Biomaterials Serves as a Transcript-Activated Matrix for Effectively Inducing Osteogenic Pathways in Stem Cells.

C. Rudolph, E. Balmayor, M. van Griensven, 2017, Stem cells and development.

A Single Methylene Group in Oligoalkylamine-Based Cationic Polymers and Lipids Promotes Enhanced mRNA Delivery.

C. Rudolph, O. Mykhaylyk, Anita Jarzębińska, 2016, Angewandte Chemie.

Chemically modified RNA induces osteogenesis of stem cells and human tissue explants as well as accelerates bone healing in rats.

C. Rudolph, E. Balmayor, O. Mykhaylyk, 2016, Biomaterials.

First Theoretic Analysis of Magnetic Drug Targeting in the Lung

Carsten Rudolph, Thomas Weyh, Stefan M. Goetz, 2010, IEEE Transactions on Biomedical Engineering.

Magnetized Aerosols Comprising Superparamagnetic Iron Oxide Nanoparticles Improve Targeted Drug and Gene Delivery to the Lung

Bernhard Gleich, Lutz Trahms, Johannes Geiger, 2012, Pharmaceutical Research.

Expression of therapeutic proteins after delivery of chemically modified mRNA in mice

J. Rosenecker, C. Rudolph, M. Griese, 2011, Nature Biotechnology.

Magnetic aerosol targeting of nanoparticles to cancer: nanomagnetosols.

C. Rudolph, B. Gleich, A. Flemmer, 2010, Methods in molecular biology.

Targeted gene delivery to the lung

C. Rudolph, J. Geiger, M. Aneja, 2009, Expert opinion on drug delivery.

Extracellular barriers in respiratory gene therapy☆

Kevin Braeckmans, Carsten Rudolph, Stefaan C De Smedt, 2008, Advanced Drug Delivery Reviews.

Aerosol gene delivery to the murine lung is mouse strain dependent

Joseph Rosenecker, Carsten Rudolph, Christian Plank, 2007, Journal of Molecular Medicine.

Biocompatible, Thermoresponsive, and Biodegradable: Simple Preparation of “All-in-One” Biorelevant Polymers

S. Agarwal, J. Andrieu, C. Rudolph, 2007 .

Delivery of mRNA Therapeutics for the Treatment of Hepatic Diseases.

C. Rudolph, C. Plank, M. Aneja, 2019, Molecular therapy : the journal of the American Society of Gene Therapy.

Aerosolized BC-819 Inhibits Primary but Not Secondary Lung Cancer Growth

A. Hochberg, C. Rudolph, M. Aneja, 2011, PloS one.

Interaction of bronchoalveolar lavage fluid with polyplexes and lipoplexes: analysing the role of proteins and glycoproteins

R. Müller, J. Rosenecker, C. Rudolph, 2003, The journal of gene medicine.

Current prospects for mRNA gene delivery.

Joseph Rosenecker, Carsten Rudolph, Michael Kormann, 2009, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Cleavage of CXCR1 on neutrophils disables bacterial killing in cystic fibrosis lung disease

C. Rudolph, P. Hordijk, D. Reinhardt, 2007, Nature Medicine.

Recent developments in example-based texture synthesis for graphics rendering

Carsten Rudolph, C. Rudolph, 2016, GI-Jahrestagung.

Cystic fibrosis transmembrane conductance regulator‐mRNA delivery: a novel alternative for cystic fibrosis gene therapy

J. Rosenecker, C. Rudolph, G. Leier, 2013, The journal of gene medicine.

Tendon healing induced by chemically modified mRNAs.

E. Weber, C. Rudolph, J. Geiger, 2017, European cells & materials.

Dry powder aerosols of polyethylenimine (PEI)-based gene vectors mediate efficient gene delivery to the lung.

C. Rudolph, W. Friess, Marc Schneider, 2011, Journal of controlled release : official journal of the Controlled Release Society.

The effect of CpG motifs on gene expression and clearance kinetics of aerosol administered polyethylenimine (PEI)-plasmid DNA complexes in the lung.

C. Rudolph, E. Lesina, P. Dames, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Application of Novel Solid Lipid Nanoparticle (SLN)-Gene Vector Formulations Based on a Dimeric HIV-1 TAT-Peptide in Vitro and in Vivo

Joseph Rosenecker, Carsten Rudolph, Christian Plank, 2004, Pharmaceutical Research.

Nonviral gene delivery to the lung with copolymer-protected and transferrin-modified polyethylenimine.

R. Müller, J. Rosenecker, C. Rudolph, 2002, Biochimica et biophysica acta.

Targeting of the glucocorticoid hormone receptor with plasmid DNA comprising glucocorticoid response elements improves nonviral gene transfer efficiency in the lungs of mice

C. Rudolph, M. Aneja, C. Maucksch, 2007, The journal of gene medicine.

Self-assembled peptide–poloxamine nanoparticles enable in vitro and in vivo genome restoration for cystic fibrosis

Joseph Rosenecker, Peter Braubach, Carsten Rudolph, 2019, Nature Nanotechnology.

Oligomers of the Arginine-rich Motif of the HIV-1 TAT Protein Are Capable of Transferring Plasmid DNA into Cells* 210

R. Müller, J. Rosenecker, C. Rudolph, 2003, The Journal of Biological Chemistry.

Magnetized Aerosols Comprising Superparamagnetic Iron Oxide Nanoparticles Improve Targeted Drug and Gene Delivery to the Lung

L. Trahms, C. Rudolph, F. Wiekhorst, 2012, Pharmaceutical Research.

CpG-free plasmid DNA prevents deterioration of pulmonary function in mice.

T. Kirchner, C. Rudolph, E. Lesina, 2010, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Translation of Angiotensin-Converting Enzyme 2 upon Liver- and Lung-Targeted Delivery of Optimized Chemically Modified mRNA

C. Rudolph, Christian Dohmen, C. Plank, 2017, Molecular therapy. Nucleic acids.

Role of biophysical parameters on ex vivo and in vivo gene transfer to the airway epithelium by polyethylenimine/albumin complexes.

C. Rudolph, A. Doherty, M. Conese, 2008, Biomacromolecules.

Thyroid hormone (T3)-modification of polyethyleneglycol (PEG)-polyethyleneimine (PEI) graft copolymers for improved gene delivery to hepatocytes.

J. Rosenecker, C. Rudolph, A. Thünemann, 2007, Biomaterials.

Alternative oxidase encoded by sequence-optimized and chemically-modified RNA transfected into mammalian cells is catalytically active

H. Jacobs, N. Weissmann, C. Rudolph, 2021, Gene therapy.

Chemically Modified Messenger RNA: Modified RNA Application for Treatment of Achilles Tendon Defects.

S. Milz, P. Foehr, A. Imhoff, 2019, Tissue engineering. Part A.

Transgene expression of transfected supercoiled plasmid DNA concatemers in mammalian cells

Alexander Bohla, Carsten Rudolph, C. Rudolph, 2009, The journal of gene medicine.