D. Penque

发表

Five percent of normal cystic fibrosis transmembrane conductance regulator mRNA ameliorates the severity of pulmonary disease in cystic fibrosis.

M. Amaral, A. Ramalho, S. Beck, 2002, American journal of respiratory cell and molecular biology.

Proteomics in the Assessment of the Therapeutic Response of Antineoplastic Drugs: Strategies and Practical Applications.

D. Penque, Lazar Popovic, Vukosava M Torres, 2016, Methods in molecular biology.

Proteomic analysis of nasal cells from cystic fibrosis patients and non‐cystic fibrosis control individuals: Search for novel biomarkers of cystic fibrosis lung disease

T. Luider, M. Amaral, D. Penque, 2006, Proteomics.

Profiling the erythrocyte membrane proteome isolated from patients diagnosed with chronic obstructive pulmonary disease.

T. Veenstra, H. Issaq, D. Penque, 2012, Journal of proteomics.

Analytical techniques for multiplex analysis of protein biomarkers

K. Kyriacou, J. Vacek, T. Luider, 2020, Expert review of proteomics.

Two‐dimensional gel electrophoresis and mass spectrometry for biomarker discovery

Deborah Penque, D. Penque, 2009, Proteomics. Clinical applications.

Molecular profiling of the human nasal epithelium: A proteomics approach

Francisco M. Couto, T. Veenstra, Daniel Faria, 2011, Journal of Proteomics.

Supramolecular organizations in the aerobic respiratory chain of Escherichia coli.

T. Conrads, D. Penque, B. Hood, 2011, Biochimie.

Title Overview of proteomics studies in obstructive sleep apnea

A. Malhotra, D. Penque, R. Matthiesen, 2015 .

Overview of proteomics studies in obstructive sleep apnea.

A. Malhotra, D. Penque, R. Matthiesen, 2015, Sleep medicine.

Chronic Obstructive Pulmonary Disease and Proteomics: A Match for

D. Penque, R. Jorge, 2012 .

Bottom up proteomics data analysis strategies to explore protein modifications and genomic variants

D. Penque, R. Matthiesen, A. S. Carvalho, 2015, Proteomics.

Low temperature restoring effect on F508del-CFTR misprocessing: A proteomic approach.

D. Penque, A. Coelho, P. Gomes-Alves, 2009, Journal of proteomics.

Proteomic biomarker discovery for the monogenic disease cystic fibrosis

D. Penque, 2007, Expert review of proteomics.

Proteome analysis of a human liver carcinoma cell line stably expressing hepatitis delta virus ribonucleoproteins.

D. Penque, N. Freitas, C. Cunha, 2009, Journal of proteomics.

Clinical proteomics stretch goals: EuPA 2012 roundtable report.

M. Baker, D. Penque, S. Surinova, 2013, Journal of proteomics.

Rescue of F508del-CFTR by RXR motif inactivation triggers proteome modulation associated with the unfolded protein response.

Francisco M. Couto, Catia Pesquita, F. Couto, 2010, Biochimica et biophysica acta.

Proteomic analysis of naphthalene-induced airway epithelial injury and repair in a cystic fibrosis mouse model.

T. Luider, M. Wilke, D. Penque, 2009, Journal of proteome research.

Human-specific cystic fibrosis transmembrane conductance regulator antibodies detect in vivo gene transfer to ovine airways.

D. Porteous, M. Amaral, D. Penque, 2006, American journal of respiratory cell and molecular biology.

Evaluation of the clinical significance of homB, a novel candidate marker of Helicobacter pylori strains associated with peptic ulcer disease.

F. Mégraud, D. Penque, B. Nunes, 2008, The Journal of infectious diseases.

Ceruloplasmin expression by human peripheral blood lymphocytes: a new link between immunity and iron metabolism.

D. Penque, R. Malhó, E. Paixão, 2008, Free radical biology & medicine.

Sequence of one α- and two β-tubulin genes of Tetrahymena pyriformis: Structural and functional relationships with other eukaryotic tubulin genes

C. Rodrigues-Pousada, P. Denoulet, L. Cyrne, 1988 .

A comparison of 14 antibodies for the biochemical detection of the cystic fibrosis transmembrane conductance regulator protein.

M. Amaral, C. Farinha, D. Penque, 2004, Molecular and cellular probes.

Antibodies for CFTR studies.

G. Lukács, M. Amaral, C. Farinha, 2004, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

A Tetrahymena orthologue of the mouse chaperonin subunit CCT gamma and its coexpression with tubulin during cilia recovery.

C. Rodrigues-Pousada, H. Soares, D. Penque, 1994, The Journal of biological chemistry.

EuPA News from the EuPA Conference and Communication Committee (CCC)

Paola Roncada, Fernando J. Corrales, Concha Gil, 2016 .

The plasma membrane-enriched fraction proteome response during adaptation to hydrogen peroxide in Saccharomyces cerevisiae

E. Herrero, H. S. Marinho, L. Cyrne, 2012, Free radical research.

Redox–Oligomeric State of Peroxiredoxin-2 and Glyceraldehyde-3-Phosphate Dehydrogenase in Obstructive Sleep Apnea Red Blood Cells under Positive Airway Pressure Therapy

D. Penque, Fátima Vaz, I. L. Martins, 2020, Antioxidants.

Transcript analysis of the cystic fibrosis splicing mutation 1525-1G>A shows use of multiple alternative splicing sites and suggests a putative role of exonic splicing enhancers

M. Amaral, A. Ramalho, S. Beck, 2003, Journal of medical genetics.

Glycation potentiates &agr;-synuclein-associated neurodegeneration in synucleinopathies

H. Lashuel, I. Martins, O. Riess, 2017, Brain : a journal of neurology.

Heat‐mediated enrichment of α‐synuclein from cells and tissue for assessing post‐translational modifications

D. Penque, J. Pimentel, J. Klucken, 2013, Journal of neurochemistry.

Serum proteomics signature of cystic fibrosis patients: a complementary 2-DE and LC-MS/MS approach.

Daniel Faria, Francisco M. Couto, Deborah Penque, 2011, Journal of proteomics.

Effects of positive airway pressure therapy on cardiovascular and metabolic markers in males with obstructive sleep apnea.

D. Penque, A. Feliciano, P. Pinto, 2017, Revista portuguesa de pneumologia.

Assessment of CFTR localisation in native airway epithelial cells obtained by nasal brushing.

J. Clancy, Z. Bebők, M. Amaral, 2004, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Cystic Fibrosis F508del Patients Have Apically Localized CFTR in a Reduced Number of Airway Cells

M. Amaral, S. Beck, C. Farinha, 2000, Laboratory Investigation.

Applicability of Different Antibodies for the Immunohistochemical Localization of CFTR In Respiratory and Intestinal Tissues of Human and Murine Origin

C. Férec, M. Amaral, D. Penque, 2003, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Establishment and Characterization of a Novel Polarized MDCK Epithelial Cellular Model for CFTR Studies

J. Wakefield, Z. Bebők, M. Amaral, 2005, Cellular Physiology and Biochemistry.

Changes in the proteome of Huh7 cells induced by transient expression of hepatitis D virus RNA and antigens.

D. Penque, C. Cunha, A. Coelho, 2008, Journal of proteomics.

Environmental Tobacco Smoke in Occupational Settings: Effect and Susceptibility Biomarkers in Workers From Lisbon Restaurants and Bars

M. J. Silva, D. Penque, Fátima Vaz, 2021, Frontiers in Public Health.

Occupational Exposure to Environmental Tobacco Smoke: A Study in Lisbon Restaurants

D. Penque, F. Aguiar, Tânia Simões, 2012, Journal of Toxicology and Environmental Health, Part A.

Diagnostic and prognostic biomarker discovery strategies for autoimmune disorders.

D. Cahill, T. Conrads, D. Penque, 2010, Journal of proteomics.

Hematological evaluation in males with obstructive sleep apnea before and after positive airway pressure.

D. Penque, R. Marçôa, R. Linhas, 2017, Revista portuguesa de pneumologia.

What have we learned from mouse models for cystic fibrosis?

D. Penque, B. Scholte, I. Carvalho-Oliveira, 2007, Expert review of molecular diagnostics.

Unusually common cystic fibrosis mutation in Portugal encodes a misprocessed protein.

M. Amaral, C. Farinha, D. Penque, 2003, Biochemical and biophysical research communications.

Biochemical methods to assess CFTR expression and membrane localization.

G. Lukács, M. Amaral, C. Farinha, 2004, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

The mechanism of sirtuin 2–mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease

Deborah Penque, Stefan Becker, Laetitia Francelle, 2017, PLoS biology.

Signaling pathways of proteostasis network unraveled by proteomic approaches on the understanding of misfolded protein rescue.

D. Penque, P. Gomes-Alves, Sofia Neves, 2011, Methods in enzymology.

A possible approach for gel-based proteomic studies in recalcitrant woody plants

D. Penque, M. S. Pais, Fátima Vaz, 2013, SpringerPlus.

Chronic Obstructive Pulmonary Disease and Proteomics: A Match for Success?

D. Penque, Bruno M. Alex, 2012 .

Systematic review on recent potential biomarkers of chronic obstructive pulmonary disease

D. Penque, J. Zoidakis, E. Aydindogan, 2018, Expert review of molecular diagnostics.

Global Mass Spectrometry and Transcriptomics Array Based Drug Profiling Provides Novel Insight into Glucosamine Induced Endoplasmic Reticulum Stress*

Rune Matthiesen, Deborah Penque, Ana Sofia Carvalho, 2014, Molecular & Cellular Proteomics.

Effects of Occupational Exposure to Tobacco Smoke: Is There a Link Between Environmental Exposure and Disease?

D. Penque, F. Gomes, Vukosava M Torres, 2013, Journal of toxicology and environmental health. Part A.

Cystic fibrosis patients with the 3272-26A>G splicing mutation have milder disease than F508del homozygotes: a large European study

X. Estivill, T. Dörk, C. Clavel, 2001, Journal of medical genetics.

Evening and morning peroxiredoxin-2 redox/oligomeric state changes in obstructive sleep apnea red blood cells: Correlation with polysomnographic and metabolic parameters.

A. Malhotra, D. Penque, Vesna Prosinecki, 2017, Biochimica et biophysica acta. Molecular basis of disease.

The human DnaJ homologue (Hdj)-1/heat-shock protein (Hsp) 40 co-chaperone is required for the in vivo stabilization of the cystic fibrosis transmembrane conductance regulator by Hsp70.

M. Amaral, C. Farinha, D. Penque, 2002, The Biochemical journal.

Facing challenges in Proteomics today and in the coming decade: Report of Roundtable Discussions at the 4th EuPA Scientific Meeting, Portugal, Estoril 2010.

Fredrik Levander, Jürgen Cox, Eugene Kolker, 2011, Journal of proteomics.

Multiple alpha-tubulin isoforms in cilia and cytoskeleton of Tetrahymena pyriformis generated by post-translational modifications. Studies during reciliation.

C. Rodrigues-Pousada, D. Penque, L. Galego, 1991, European journal of biochemistry.

SELDI-TOF biomarker signatures for cystic fibrosis, asthma and chronic obstructive pulmonary disease.

D. Porteous, R. Gray, D. Penque, 2010, Clinical biochemistry.

Ionic transport in tall columnar epithelial (TCE) cells obtained by nasal brushing from non-cystic fibrosis (CF) individuals.

M. Amaral, D. Penque, A. Maurício, 2004, Acta medica portuguesa.

Correction: The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease

S. Kügler, H. Lashuel, S. Becker, 2017, PLoS biology.

For Peer Review Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies

Hilal, Jochen, Quintas, 2017 .

Proteomics uncovering possible key players in F508del-CFTR processing and trafficking

D. Penque, P. Gomes-Alves, 2010, Expert review of proteomics.

Proteomics techniques for cystic fibrosis research.

G. Lukács, M. Amaral, G. Heda, 2004, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

CFTR Localization in Native Airway Cells and Cell Lines Expressing Wild-type or F508del-CFTR by a Panel of Different Antibodies

M. Amaral, M. Tzetis, D. Penque, 2004, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Immunohistochemistry of CFTR in native tissues and primary epithelial cell cultures.

C. Férec, M. Amaral, D. Penque, 2004, Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society.

Evening and morning alterations in Obstructive Sleep Apnea red blood cell proteome

A. Malhotra, D. Penque, Vesna Prosinecki, 2017, Data in brief.

Cystic fibrosis patients with the 3272‐26A→G mutation have mild disease, leaky alternative mRNA splicing, and CFTR protein at the cell membrane

M. Amaral, S. Beck, C. Farinha, 1999, Human mutation.

Proteomics in Detection and Monitoring Chronic Lung Diseases: The Human Nasal Epithelium as a Molecular Model

D. Penque, B. Alexandre, N. Charro, 2012 .