D. Schümperli

发表

Nuclear antisense effects in cyclophilin A pre-mRNA splicing by oligonucleotides: a comparison of tricyclo-DNA with LNA.

D. Ittig, Songkai Liu, D. Renneberg, 2004, Nucleic acids research.

Double-target antisense U7 snRNAs promote efficient skipping of an aberrant exon in three human beta-thalassemic mutations.

R. Tomasini, R. Kole, D. Schümperli, 1999, Human molecular genetics.

Rescue of a severe mouse model for spinal muscular atrophy by U7 snRNA-mediated splicing modulation.

D. Trono, M. Ruepp, D. Schümperli, 2009, Human molecular genetics.

Affecting gene expression by altering the length and sequence of the 5' leader.

D. Schümperli, M. Rosenberg, H. Johansen, 1984, Proceedings of the National Academy of Sciences of the United States of America.

The stem-loop binding protein stimulates histone translation at an early step in the initiation pathway.

N. Gray, D. Schümperli, A. Schaller, 2005, RNA.

The expression in yeast of the Escherichia coli galK gene on CYC1::galK fusion plasmids.

D. Schümperli, M. Rosenberg, R. Zitomer, 1983, Gene.

The craniosacral progression of muscle development influences the emergence of neuromuscular junction alterations in a severe murine model for spinal muscular atrophy

D. Schümperli, A. Neve, Tilman Voigt, 2014, Neuropathology and applied neurobiology.

Toward an Assembly Line for U7 snRNPs INTERACTIONS OF U7-SPECIFIC Lsm PROTEINS WITH PRMT5 AND SMN COMPLEXES *

G. Meister, D. Schümperli, C. Däpp, 2005 .

Cycling in the nucleus: regulation of RNA 3' processing and nuclear organization of replication-dependent histone genes.

D. Schümperli, Valentina Romeo, 2016, Current opinion in cell biology.

Mammalian pre-mRNA 3' end processing factor CF I m 68 functions in mRNA export.

S. Cardinale, M. Ruepp, D. Schümperli, 2009, Molecular biology of the cell.

A large animal model of spinal muscular atrophy and correction of phenotype

W. Arnold, D. Schümperli, B. Kaspar, 2015, Annals of neurology.

Central and peripheral defects in motor units of the diaphragm of spinal muscular atrophy mice

S. Saxena, D. Schümperli, J. Trüb, 2016, Molecular and Cellular Neuroscience.

Delta-aminolevulinic acid synthase 2 expression in combination with iron as modifiers of disease severity in erythropoietic protoporphyria.

Jonathan Hall, D. Schümperli, X. Schneider-Yin, 2019, Molecular genetics and metabolism.

Efficient expression of Escherichia coli galactokinase gene in mammalian cells.

B. Howard, D. Schümperli, M. Rosenberg, 1982, Proceedings of the National Academy of Sciences of the United States of America.

HindIII and Sst I restriction sites mapped on rabbit poxvirus and vaccinia virus DNA

D. Schümperli, S. Stoffel, R. Wittek, 1977, Journal of virology.

Innate-Like Control of Human iNKT Cell Autoreactivity via the Hypervariable CDR3β Loop

B. Jakobsen, D. Schümperli, P. Villiger, 2010, PLoS biology.

Isolation of neuronal nuclei from rat brain cortex, rat cerebellum, and pigeon forebrain.

D. Schümperli, C. Kuenzle, A. Knüsel, 1977, Methods in cell biology.

Cell-cycle regulation of histone gene expression

D. Schümperli, 1986, Cell.

Antisense genes to induce exon inclusion.

D. Schümperli, R. Nlend, 2012, Methods in molecular biology.

Toward an Assembly Line for U7 snRNPs

G. Meister, D. Schümperli, C. Däpp, 2005, Journal of Biological Chemistry.

U7 snRNP-specific Lsm11 protein: dual binding contacts with the 100 kDa zinc finger processing factor (ZFP100) and a ZFP100-independent function in histone RNA 3′ end processing

D. Schümperli, A. Gruber, Teldja N. Azzouz, 2005, Nucleic acids research.

U 7 snRNP-specific Lsm 11 protein : dual binding contacts with the 100 kDa zinc finger processing factor ( ZFP 100 ) and a ZFP 100-independent function in histone RNA 3 0 end processing

D. Schümperli, A. Gruber, Teldja N. Azzouz, 2005 .

proteins for the first nucleotide in the histone mRNA hairpin loop Specificities of Caenorhabditis elegans and human hairpin binding

D. Schümperli, B. Müller, F. Michel, 2000 .

A 5'-3' exonuclease activity involved in forming the 3' products of histone pre-mRNA processing in vitro.

D. Schümperli, B. Müller, T. Walther, 1998, RNA.

Variable effects of the conserved RNA hairpin element upon 3' end processing of histone pre-mRNA in vitro.

D. Soldati, D. Schümperli, A. Streit, 1993, Nucleic acids research.

Biochemical demonstration of complex formation of histone pre‐mRNA with U7 small nuclear ribonucleoprotein and hairpin binding factors.

D. Soldati, D. Schümperli, A. Streit, 1992, The EMBO journal.

3' processing of pre-mRNA plays a major role in proliferation-dependent regulation of histone gene expression.

D. Schümperli, C. Stauber, Daniel Schümperli, 1988, Nucleic acids research.

A signal regulating mouse histone H4 mRNA levels in a mammalian cell cycle mutant and sequences controlling RNA 3′ processing are both contained within the same 80‐bp fragment.

D. Schümperli, R. Eckner, B. Lüscher, 1986, The EMBO journal.

Development and characterization of a triple combination gene therapy vector inhibiting HIV‐1 multiplication

D. Trono, D. Schümperli, I. Barde, 2008, The journal of gene medicine.

Somatic Therapy of a Mouse SMA Model with a U7 snRNA Gene Correcting SMN2 Splicing

D. Schümperli, R. Fricker, J. Trüb, 2016, Molecular therapy : the journal of the American Society of Gene Therapy.

CstF64: Cell Cycle Regulation and Functional Role in 3′ End Processing of Replication-Dependent Histone mRNAs

D. Schümperli, Valentina Romeo, Esther Griesbach, 2014, Molecular and Cellular Biology.

Interactions of CstF-64, CstF-77, and symplekin: Implications on localisation and function

M. Ruepp, D. Schümperli, C. Schweingruber, 2011, Molecular biology of the cell.

Ultrastructural changes in diaphragm neuromuscular junctions in a severe mouse model for Spinal Muscular Atrophy and their prevention by bifunctional U7 snRNA correcting SMN2 splicing

D. Schümperli, K. Meyer, O. Baum, 2010, Neuromuscular Disorders.

3' editing of mRNAs: sequence requirements and involvement of a 60-nucleotide RNA in maturation of histone mRNA precursors.

C. Birchmeier, D. Schümperli, M. Birnstiel, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1‐like protein

C. Will, R. Lührmann, D. Schümperli, 2001, The EMBO journal.

Histone-specific RNA 3' processing in nuclear extracts from mammalian cells.

D. Soldati, D. Schümperli, B. Lüscher, 1990, Methods in enzymology.

Genetic and antigenic heterogeneity of different parapoxvirus strains.

M. Herlyn, D. Schümperli, P. Bachmann, 1980, Intervirology.

Modeling the ferrochelatase c.315-48C modifier mutation for erythropoietic protoporphyria (EPP) in mice

Vijay B. Bansode, D. Schümperli, X. Schneider-Yin, 2017, Disease Models & Mechanisms.

Antisense Derivatives of U7 Small Nuclear RNA as Modulators of Pre‐mRNA Splicing

D. Schümperli, K. Meyer, 2012 .

Polydnavirus DNA of the braconid wasp Chelonus inanitus is integrated in the wasp's genome and excised only in later pupal and adult stages of the female.

D. Schümperli, A. Gruber, B. Lanzrein, 1996, The Journal of general virology.

Stable alteration of pre-mRNA splicing patterns by modified U7 small nuclear RNAs.

R. Kole, D. Schümperli, D. Suter, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Detection of UV-induced RNA:protein crosslinks in snRNPs by oligonucleotides complementary to the snRNA.

D. Schümperli, R. Mital, U. Albrecht, 1993, Nucleic acids research.

The C-terminal domain of coilin interacts with Sm proteins and U snRNPs

D. Schümperli, R. Pillai, C. Kambach, 2005, Chromosoma.

Structural and functional organization of the gpt gene region of Escherichia coli.

D. Schümperli, J. Nüesch, 1984, Gene.

Functional importance of conserved nucleotides at the histone RNA 3' processing site.

A. Furger, D. Schümperli, A. Schaller, 1998, RNA.

Structural and functional characterization of mouse U7 small nuclear RNA active in 3' processing of histone pre-mRNA

D. Soldati, D. Schümperli, 1988 .

Transcriptional and Post-Transcriptional Control of Histone Gene Expression

D. Schümperli, 1985 .

Synthesis and cellular activity of stereochemically-pure 2'-O-(2-methoxyethyl)-phosphorothioate oligonucleotides.

D. Schümperli, H. Lightfoot, M. Li, 2017, Chemical communications.

Comparison of five poxvirus genomes by analysis with restriction endonucleases HindIII, BamI and EcoRI.

W. Schaffner, D. Schümperli, R. Wittek, 1978, The Journal of general virology.

Antisense properties of tricyclo-DNA

Christian J. Leumann, Dorte Renneberg, Emilie Bouliong, 2002, Nucleic Acids Res..

Biochemical studies of U7 snRNPs and of histone RNA 3′ processing

D. Soldati, R. Lührmann, D. Schümperli, 2004, Molecular Biology Reports.

The structure of tandem regulatory regions in the deo operon of Escherichia coli K12

H. Aiba, P. Valentin‐Hansen, D. Schümperli, 1982, The EMBO journal.

The special Sm core structure of the U7 snRNP: far-reaching significance of a small nuclear ribonucleoprotein

D. Schümperli, R. Pillai, D. Schümperli, 2004, Cellular and Molecular Life Sciences CMLS.

Structural and functional characterization of mouse U7 small nuclear RNA active in 3' processing of histone pre-mRNA.

D. Soldati, D. Schümperli, D Soldati, 1988, Molecular and cellular biology.

Structure of a mouse histone-encoding gene cluster.

D. Schümperli, A. Streit, A. Gruber, 1990, Gene.

Spinal muscular atrophy: SMN2 pre-mRNA splicing corrected by a U7 snRNA derivative carrying a splicing enhancer sequence.

B. Rothen‐Rutishauser, D. Schümperli, K. Meyer, 2007, Molecular therapy : the journal of the American Society of Gene Therapy.

Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing.

Utz Fischer, Daniel Schümperli, Gunter Meister, 2003, Genes & development.

The Caenorhabditis elegans histone hairpin-binding protein is required for core histone gene expression and is essential for embryonic and postembryonic cell division.

Catriona Crombie, D. Schümperli, J. Pettitt, 2002, Journal of cell science.

Histone H4 mRNA from the nematode Ascaris lumbricoides is cis-spliced and polyadenylated.

D. Schümperli, D. Suter, V. Bernard, 1997, Biochimica et biophysica acta.

The gene for histone RNA hairpin binding protein is located on human chromosome 4 and encodes a novel type of RNA binding protein

A. Schaller, D. Schümperli, B. Müller, 1997, The EMBO journal.

FUS/TLS contributes to replication-dependent histone gene expression by interaction with U7 snRNPs and histone-specific transcription factors

M. Heller, M. Ruepp, D. Schümperli, 2015, Nucleic acids research.

Regulation of histone mRNA in the unperturbed cell cycle: evidence suggesting control at two posttranscriptional steps

D. Schümperli, W. Marzluff, M. Harris, 1991, Molecular and cellular biology.

RNAs and ribonucleoproteins in recognition and catalysis.

D. Schümperli, T. H. Wittop Koning, Tom H. Wittop Koning, 1994, European journal of biochemistry.

Assembly, nuclear import and function of U7 snRNPs studied by microinjection of synthetic U7 RNA into Xenopus oocytes.

B. Stefanovic, R. Lührmann, D. Schümperli, 1995, Nucleic acids research.

Multilevel regulation of replication-dependent histone genes.

D. Schümperli, 1988, Trends in genetics : TIG.

Inhibition of HIV‐1 multiplication by a modified U7 snRNA inducing Tat and Rev exon skipping

D. Trono, Songkai Liu, D. Schümperli, 2007, The journal of gene medicine.

Antisense derivatives of U7 and other small nuclear RNAs as tools to modify pre-mRNA splicing patterns

R. Kole, D. Schümperli, M. Asparuhova, 2004 .

Inhibition of HIV-1 multiplication by antisense U7 snRNAs and siRNAs targeting cyclophilin A.

T. Klimkait, Songkai Liu, D. Schümperli, 2004, Nucleic acids research.

The low abundance of U7 snRNA is partly determined by its Sm binding site.

B. Stefanovic, D. Schümperli, C. Grimm, 1993, The EMBO journal.

Splicing changes in SMA mouse motoneurons and SMN-depleted neuroblastoma cells: Evidence for involvement of splicing regulatory proteins

J. Ule, M. Kayikci, S. Saxena, 2014, RNA biology.

Inverted terminal repeats in rabbit poxvirus and vaccinia virus DNA

D. Schümperli, R. Wittek, P. Boseley, 1978, Journal of virology.

RNA 3′ processing regulates histone mRNA levels in a mammalian cell cycle mutant. A processing factor becomes limiting in G1‐arrested cells.

D. Schümperli, B. Lüscher, 1987, The EMBO journal.

U7 snRNAs induce correction of mutated dystrophin pre-mRNA by exon skipping

H. Lochmüller, J. Burgunder, Hanns Lochmüller, 2003, Cellular and Molecular Life Sciences CMLS.

Polydnavirus of the parasitic wasp Chelonus inanitus (Braconidae): characterization, genome organization and time point of replication.

D. Schümperli, A. Gruber, B. Lanzrein, 1994, The Journal of general virology.

Repurposing of glycine transport inhibitors for the treatment of erythropoietic protoporphyria.

Jonathan Hall, M. Ruepp, D. Schümperli, 2021, Cell chemical biology.

Delivery of oligonucleotides to bone marrow to modulate ferrochelatase splicing in a mouse model of erythropoietic protoporphyria

Jonathan Hall, D. Schümperli, X. Schneider-Yin, 2020, bioRxiv.

3' end processing of mouse histone pre-mRNA: evidence for additional base-pairing between U7 snRNA and pre-mRNA.

B. Stefanovic, D. Schümperli, A. Streit, 1994, Nucleic acids research.

mRNA 3′ end processing and more—multiple functions of mammalian cleavage factor I‐68

M. Ruepp, D. Schümperli, S. Barabino, 2011, Wiley interdisciplinary reviews. RNA.

Faithful cell-cycle regulation of a recombinant mouse histone H4 gene is controlled by sequences in the 3'-terminal part of the gene.

D. Schümperli, B. Lüscher, R. Schindler, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Specificities of Caenorhabditis elegans and human hairpin binding proteins for the first nucleotide in the histone mRNA hairpin loop.

D. Schümperli, B. Müller, F. Michel, 2000, RNA.

Positive and negative mutant selection in the human histone hairpin-binding protein using the yeast three-hybrid system.

Daniel Zenklusen, D. Schümperli, B. Müller, 2000, Nucleic acids research.

Translational coupling at an intercistronic boundary of the Escherichia coli galactose operon

D. Schümperli, K. Mckenney, M. Rosenberg, 1982, Cell.

DNA sequence homology estimation by combinatorial analysis of endonuclease restriction data.

D. Schümperli, R. Lagadec, H. K. Müller, 1978, The Journal of general virology.

Positive cofactor 4 (PC4) contributes to the regulation of replication-dependent canonical histone gene expression

J. Dolata, D. Schümperli, W. Juzwa, 2018, BMC Molecular Biology.

Sensitivity of splice sites to antisense oligonucleotides in vivo.

R. Kole, D. Schümperli, H. Sierakowska, 1999, RNA.

The 68 kDa subunit of mammalian cleavage factor I interacts with the U7 small nuclear ribonucleoprotein and participates in 3′-end processing of animal histone mRNAs

M. Ruepp, D. Schümperli, R. Pillai, 2010, Nucleic acids research.

Nucleotide sequence of two mouse histone H4 genes.

D. Schümperli, R. Böhni, V. Meier, 1989, Nucleic acids research.

Structures of four human pseudogenes for U7 small nuclear RNA.

D. Soldati, D. Schümperli, D Soldati, 1990, Gene.

The bona fide mouse U7 snRNA gene maps to a different chromosome than two U7 pseudogenes.

D. Schümperli, A. Matera, A. Whalen, 1996, Genomics.

A synthetic histone pre-mRNA-U7 small nuclear RNA chimera undergoing cis cleavage in the cytoplasm of Xenopus oocytes.

B. Stefanovic, D. Schümperli, T. H. Wittop Koning, 1995, Nucleic acids research.

Isolation of an active gene and of two pseudogenes for mouse U7 small nuclear RNA.

D. Soldati, D. Schümperli, A. Gruber, 1991, Biochimica et biophysica acta.

Regulation of histone gene expression.

M. Busslinger, D. Schümperli, M. Birnstiel, 1985, Cold Spring Harbor symposia on quantitative biology.

Location of a new endonuclease restriction site associated with a temperature-sensitive mutation of vaccinia virus.

G. McFadden, D. Schümperli, S. Dales, 1980, Virology.

Symmetrical arrangement of the heterologous regions of rabbit poxvirus and vaccinia virus DNA.

D. Schümperli, R. Wittek, R. Wyler, 1980, The Journal of general virology.

Doxycycline-controlled splicing modulation by regulated antisense U7 snRNA expression cassettes

D. Schümperli, J. Marquis, L. Angehrn, 2009, Gene Therapy.

Structure of the histone mRNA hairpin required for cell cycle regulation of histone gene expression.

M. Nilges, Catriona Crombie, J. Linge, 2002, RNA.

The primary structure of the precursor of chicken mitochondrial aspartate aminotransferase. Cloning and sequence analysis of cDNA.

P. Christen, R. Jaussi, D. Schümperli, 1985, Journal of Biological Chemistry.

Rescue of a severe mouse model for spinal muscular atrophy by U7 snRNA-mediated splicing modulation.

D. Trono, M. Ruepp, D. Schümperli, 2009, Human molecular genetics.

Regulation of histone mRNA in the unperturbed cell cycle: evidence suggesting control at two posttranscriptional steps

D. Schümperli, W. Marzluff, M. Harris, 1991, Molecular and cellular biology.

The stem-loop binding protein stimulates histone translation at an early step in the initiation pathway.

N. Gray, D. Schümperli, A. Schaller, 2005, RNA.

Synthesis and cellular activity of stereochemically-pure 2'-O-(2-methoxyethyl)-phosphorothioate oligonucleotides.

D. Schümperli, H. Lightfoot, A. Behera, 2017, Chemical communications.

Rudolf Weber (1922–2015): a driving force in the transition of developmental biology into a molecular and cellular science

D. Schümperli, 2016, Development Genes and Evolution.

Permeability changes of plasma and lysosomal membranes in HeLa cells infected with rabbit poxvirus

D. Schümperli, E. Peterhans, R. Wyler, 2005, Archives of Virology.