C. Simon

发表

Dysregulation of Mdm2 and Mdm4 alternative splicing underlies motor neuron death in spinal muscular atrophy

G. Mentis, Meaghan Van Alstyne, C. Simon, 2018, Genes & development.

P90 Ribosomal s6 kinase 2 negatively regulates axon growth in motoneurons

M. Heisenberg, C. Simon, B. Holtmann, 2009, Molecular and Cellular Neuroscience.

Central synaptopathy is the most conserved feature of motor circuit pathology across spinal muscular atrophy mouse models

T. Langenhan, C. Simon, Beatriz Blanco-Redondo, 2021, iScience.

A Stem Cell Model of the Motor Circuit Uncouples Motor Neuron Death from Hyperexcitability Induced by SMN Deficiency.

J. Tapia, G. Mentis, C. Simon, 2016, Cell reports.

Reduced sensory synaptic excitation impairs motor neuron function via Kv2.1 in spinal muscular atrophy

G. Mentis, C. Simon, Emily V. Fletcher, 2017, Nature Neuroscience.

Dysregulated IGFBP5 expression causes axon degeneration and motoneuron loss in diabetic neuropathy

A. Hoeflich, E. Wolf, C. Sommer, 2015, Acta Neuropathologica.

Presynaptic Localization of Smn and hnRNP R in Axon Terminals of Embryonic and Postnatal Mouse Motoneurons

C. Simon, S. Jablonka, M. Sendtner, 2014, PloS one.

Impaired prenatal motor axon development necessitates early therapeutic intervention in severe SMA

T. Crawford, G. Mentis, C. Lutz, 2021, Science Translational Medicine.

Stasimon Contributes to the Loss of Sensory Synapses and Motor Neuron Death in a Mouse Model of Spinal Muscular Atrophy

G. Mentis, Meaghan Van Alstyne, C. Simon, 2019, bioRxiv.

Converging Mechanisms of p53 Activation Drive Motor Neuron Degeneration in Spinal Muscular Atrophy.

G. Mentis, C. Henderson, Meaghan Van Alstyne, 2017, Cell reports.

Converging Mechanisms o f p 53 Activation Drive Motor Neuron Degeneration in Spinal Muscular Atrophy Graphical

G. Mentis, C. Henderson, C. Simon, 2022 .

Activity Regulates the Incidence of Heteronymous Sensory-Motor Connections

L. Abbott, T. Jessell, G. Mentis, 2015, Neuron.

The PDZ-Domain Protein Whirlin Facilitates Mechanosensory Signaling in Mammalian Proprioceptors

R. W. Banks, K. Steel, T. Jessell, 2015, The Journal of Neuroscience.

Chronic Pharmacological Increase of Neuronal Activity Improves Sensory-Motor Dysfunction in Spinal Muscular Atrophy Mice

G. Mentis, C. Simon, Emily V. Fletcher, 2020, The Journal of Neuroscience.

ALS‐Associated Endoplasmic Reticulum Proteins in Denervated Skeletal Muscle: Implications for Motor Neuron Disease Pathology

I. Katona, D. Troost, C. Simon, 2017, Brain pathology.

Ciliary neurotrophic factor-induced sprouting preserves motor function in a mouse model of mild spinal muscular atrophy.

C. Simon, S. Jablonka, M. Sendtner, 2010, Human molecular genetics.

Laser microscopy acquisition and analysis of premotor synapses in the murine spinal cord

G. Mentis, S. Hallermann, C. Simon, 2022, STAR protocols.

p53-dependent c-Fos expression is a marker but not executor for motor neuron death in spinal muscular atrophy mouse models

S. Hallermann, C. Simon, Beatriz Blanco-Redondo, 2022, Frontiers in Cellular Neuroscience.

SMN controls neuromuscular junction integrity through U7 snRNP

G. Mentis, C. Simon, L. Pellizzoni, 2021, bioRxiv.

Plastin 3 rescues cell surface translocation and activation of TrkB in spinal muscular atrophy

Teresa Klein, C. Simon, S. Jablonka, 2023, The Journal of cell biology.

Boosting neuregulin 1 type-III expression hastens SMA motor axon maturation

C. Simon, M. Denton, C. Sumner, 2023, Acta Neuropathologica Communications.