Chawnshang Chang

Chawnshang Chang, Hui-Kuan Lin, C. Cho, 2004, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Androgen Receptor in Prostate Cancer Progression

Chawnshang Chang, S. Altuwaijri, H. Miyamoto, 2008 .

Mutations in the Helix 3 Region of the Androgen Receptor Abrogate ARA70 Promotion of 17β-Estradiol-induced Androgen Receptor Transactivation*

S. Yeh, T. Thin, Chawnshang Chang, 2002, The Journal of Biological Chemistry.

Inhibition of NFκB Activity through Maintenance of IκBα Levels Contributes to Dihydrotestosterone-mediated Repression of the Interleukin-6 Promoter*

Chawnshang Chang, E. Keller, W. Ershler, 1996, The Journal of Biological Chemistry.

Identification of testosterone-/androgen receptor-regulated genes in mouse Sertoli cells.

Z. Cai, Chawnshang Chang, Wei Lu, 2012, Asian journal of andrology.

Localization and regulation of estrogen, progestin and androgen receptors in the seminal vesicle of the rhesus monkey

Chawnshang Chang, R. Brenner, S. Liao, 1990, The Journal of Steroid Biochemistry and Molecular Biology.

Differential regulation of testosterone vs. 5α-dihydrotestosterone by selective androgen response elements

T. Thin, Chawnshang Chang, P. Hsiao, 2000, Molecular and Cellular Biochemistry.

Δ5-Androstenediol is a natural hormone with androgenic activity in human prostate cancer cells

E. Messing, S. Yeh, Chawnshang Chang, 1998 .

Androgens and the Androgen Receptor in Male Sex Development and Fertility

Chawnshang Chang, L. Collins, 2002 .

The diverse and contrasting effects of using human prostate cancer cell lines to study androgen receptor roles in prostate cancer.

Hong-Chiang Chang, S. Yeh, Chawnshang Chang, 2009, Asian journal of andrology.

C19-steroids as androgen receptor modulators: design, discovery, and structure-activity relationship of new steroidal androgen receptor antagonists.

Chawnshang Chang, H. Miyamoto, H. Lardy, 2006, Bioorganic & medicinal chemistry.

Cloning and nucleotide sequence of a full-length cDNA for human liver γ-glutamylcysteine synthetase

Chawnshang Chang, R. Mulcahy, J. Gipp, 1992 .

Androgen receptor decreases the renal cell carcinoma bone metastases via suppressing the osteolytic formation through altering a novel circEXOC7 regulatory axis

Chawnshang Chang, W. Zhai, T. Sheu, 2021, Clinical and translational medicine.

Reduced osteoblast activity in the mice lacking TR4 nuclear receptor leads to osteoporosis

Chawnshang Chang, Gonghui Li, Yi-Fen Lee, 2012, Reproductive Biology and Endocrinology.

High-dose-androgen-induced autophagic cell death to suppress the Enzalutamide-resistant prostate cancer growth via altering the circRNA-BCL2/miRNA-198/AMBRA1 signaling

Chawnshang Chang, Dexin Yu, Yin Sun, 2021, Cell death discovery.

Cancer Metastasis Promotion versus Suppression of Prostate Anti-androgen Receptor ASC-J9® Lead to MDV3100/Enzalutamide versus Casodex/Bicalutamide or Therapies with Anti-androgens Differential Androgen Deprivation Molecular Bases of Disease:

S. Yeh, Chawnshang Chang, Lei Li, 2013 .

Targeting thymic epithelia AR enhances T-cell reconstitution and bone marrow transplant grafting efficacy.

S. Yeh, Chawnshang Chang, S. Altuwaijri, 2013, Molecular endocrinology.

Interruption of nuclear factor kappaB signaling by the androgen receptor facilitates 12-O-tetradecanoylphorbolacetate-induced apoptosis in androgen-sensitive prostate cancer LNCaP cells.

S. Yeh, Chawnshang Chang, Lin Yang, 2003, Cancer research.

Targeting the Lnc-OPHN1-5/androgen receptor/hnRNPA1 complex increases Enzalutamide sensitivity to better suppress prostate cancer progression

C. Liang, Jialin Meng, Chawnshang Chang, 2021, Cell Death & Disease.

Preclinical studies using cisplatin/carboplatin to restore the Enzalutamide sensitivity via degrading the androgen receptor splicing variant 7 (ARv7) to further suppress Enzalutamide resistant prostate cancer

S. Yeh, Chawnshang Chang, Y. Niu, 2020, Cell Death & Disease.

Important for the Regulation of Th 2 Immune Transcriptional Coregulator Pias 1 Is Interaction between GATA-3 and

Chawnshang Chang, D. Fowell, Yanfang Huang, 2007 .

Suppression Versus Induction of Androgen Receptor Functions by the Phosphatidylinositol 3-Kinase/Akt Pathway in Prostate Cancer LNCaP Cells with Different Passage Numbers*

Chawnshang Chang, Lin Yang, Hui-Kuan Lin, 2003, Journal of Biological Chemistry.

Silences Transcription in Human Prostate Cancer Methylation of the Androgen Receptor Minimal Promoter Updated

Yan Shi, A. Friedl, G. Bova, 2000 .

Proteomic analysis of urethral protein expression in an estrogen receptor α-deficient murine model of stress urinary incontinence

S. Yeh, Chawnshang Chang, W. Hsieh, 2015, World Journal of Urology.

Suppression of Androgen Receptor Transactivation by Pyk2 via Interaction and Phosphorylation of the ARA55 Coregulator*

S. Yeh, Chawnshang Chang, Yinglu Guo, 2002, The Journal of Biological Chemistry.

Altered prostate epithelial development and IGF‐1 signal in mice lacking the androgen receptor in stromal smooth muscle cells

Hong-Chiang Chang, S. Yeh, Chawnshang Chang, 2011, The Prostate.

Oligozoospermia with normal fertility in male mice lacking the androgen receptor in testis peritubular myoid cells

S. Yeh, Chawnshang Chang, Hung-Yun Lin, 2006, Proceedings of the National Academy of Sciences.

Increased CK5/CK8-Positive Intermediate Cells with Stromal Smooth Muscle Cell Atrophy in the Mice Lacking Prostate Epithelial Androgen Receptor

S. Yeh, Chawnshang Chang, Juan Wang, 2011, PloS one.

Abnormal Mitochondrial Function and Impaired Granulosa Cell Differentiation in Androgen Receptor Knockout Mice

S. Yeh, Chawnshang Chang, Yi-Chen Wu, 2015, International journal of molecular sciences.

Conditional knockout of the androgen receptor in gonadotropes reveals crucial roles for androgen in gonadotropin synthesis and surge in female mice.

S. Yeh, Chawnshang Chang, Sheng Wu, 2014, Molecular endocrinology.

Interaction of Cell Cycle Regulatory Proteins with the Androgen Receptor

S. Yeh, Chawnshang Chang, H. Miyamoto, 2002 .

Androgen Receptor Enhances Kidney Stone-CaOx Crystal Formation via Modulation of Oxalate Biosynthesis & Oxidative Stress

S. Yeh, D. He, Chawnshang Chang, 2014, Molecular endocrinology.

New Therapy via Targeting Androgen Receptor in Monocytes/Macrophages to Battle Atherosclerosis

Chawnshang Chang, Chiung-Kuei Huang, J. Sparks, 2014, Hypertension.

Androgen Receptor Promotes Abdominal Aortic Aneurysm Development via Modulating Inflammatory Interleukin-1&agr; and Transforming Growth Factor-&bgr;1 Expression

Chawnshang Chang, Chiung-Kuei Huang, J. Sparks, 2015, Hypertension.

Preclinical Study using Malat1 Small Interfering RNA or Androgen Receptor Splicing Variant 7 Degradation Enhancer ASC-J9® to Suppress Enzalutamide-resistant Prostate Cancer Progression.

Jun Luo, E. Antonarakis, S. Yeh, 2017, European urology.

Hypoxia increases RCC stem cell phenotype via altering the androgen receptor (AR)-lncTCFL5-2-YBX1-SOX2 signaling axis

Chawnshang Chang, W. Zhai, Junhua Zheng, 2022, Cell & Bioscience.

TR4 orphan nuclear receptor functions as an apoptosis modulator via regulation of Bcl-2 gene expression.

S. Inui, Chawnshang Chang, Wen-Lung Ma, 2007, Biochemical and biophysical research communications.

9-cis-retinoic acid inhibits androgen receptor activity through activation of retinoid X receptor.

Chawnshang Chang, S. Altuwaijri, Chinyi Chu, 2005, Molecular endocrinology.

TR2 orphan receptor functions as negative modulator for androgen receptor in prostate cancer cells PC‐3

Chawnshang Chang, X. Mu, 2003, The Prostate.

Tissue-specific knockout of androgen receptor in mice.

S. Yeh, Chawnshang Chang, Tzu-hua Lin, 2011, Methods in molecular biology.

Androgen suppresses PML protein expression in prostate cancer CWR22R cells.

J. Ni, Chawnshang Chang, Lin Yang, 2004, Biochemical and biophysical research communications.

Actin monomer enhances supervillin-modulated androgen receptor transactivation.

Chawnshang Chang, Yueh-Chiang Hu, H. Ting, 2004, Biochemical and biophysical research communications.

3β-Acetoxyandrost-1,5-diene-17-ethylene ketal functions as a potent antiandrogen with marginal agonist activity

Chawnshang Chang, H. Miyamoto, H. Lardy, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Deficits in Motor Coordination with Aberrant Cerebellar Development in Mice Lacking Testicular Orphan Nuclear Receptor 4

H. Uno, Chawnshang Chang, Yei-Tsung Chen, 2005, Molecular and Cellular Biology.

Loss of androgen receptor promotes adipogenesis but suppresses osteogenesis in bone marrow stromal cells.

Yuhchyau Chen, Chawnshang Chang, Chiung-Kuei Huang, 2013, Stem cell research.

Stromal resistance to castration-induced prostate regression in a mouse model of benign prostatic hyperplasia

S. Yeh, K. Eng, Chawnshang Chang, 2022, bioRxiv.

Targeting the TR4 nuclear receptor-mediated lncTASR/AXL signaling with tretinoin increases the sunitinib sensitivity to better suppress the RCC progression

Michiaki Hamada, Chawnshang Chang, T. Fukunaga, 2019, Oncogene.

Androgen receptor decreases the cytotoxic effects of chemotherapeutic drugs in upper urinary tract urothelial carcinoma cells

Chawnshang Chang, Wen-Lung Ma, Caixia Zhang, 2013, Oncology letters.

Differential Expression of Nur77 Family Members in Human T-Lymphotropic Virus Type 1-Infected Cells: Transactivation of theTR3/nur77 Gene by Tax Protein

Chawnshang Chang, V. Zachar, Xiangdong Liu, 1998, Journal of Virology.

mouse sera and organs with liquid chromatography tandem mass spectrometry

S. Yeh, Chawnshang Chang, Chiung-Kuei Huang, 2014 .

Deficiency in TR4 nuclear receptor abrogates Gadd45a expression and increases cytotoxicity induced by ionizing radiation

Chawnshang Chang, S. Yeh, Gonghui Li, 2012, Cellular & Molecular Biology Letters.

Human kallikrein 2 (KLK2) promotes prostate cancer cell growth via function as a modulator to promote the ARA70-enhanced androgen receptor transactivation

Jing Chen, S. Yeh, Chawnshang Chang, 2014, Tumor Biology.

Increased PrLZ-mediated androgen receptor transactivation promotes prostate cancer growth at castration-resistant stage.

Yuzhuo Wang, S. Yeh, Xin-yang Wang, 2013, Carcinogenesis.

Monocyte/macrophage androgen receptor suppresses cutaneous wound healing in mice by enhancing local TNF-alpha expression.

Chawnshang Chang, Kuang-Hsiang Chuang, Wen-Jye Lin, 2009, The Journal of clinical investigation.

Isolation and characterization of the androgen receptor mutants with divergent transcriptional activity in response to hydroxyflutamide

Chawnshang Chang, W. Young, Chihuei Wang, 2000, Endocrine.

Differential induction of androgen receptor transactivation by different androgen receptor coativators in human prostate cancer DU 145 cells

Hong-Chiang Chang, S. Yeh, Chawnshang Chang, 1999, Endocrine.

Androgen deprivation therapy for prostate cancer: Current status and future prospects

E. Messing, Chawnshang Chang, H. Miyamoto, 2004, The Prostate.

Functional Domain and Motif Analyses of Androgen Receptor Coregulator ARA70 and Its Differential Expression in Prostate Cancer*

J. Ni, S. Yeh, Jiaoti Huang, 2004, Journal of Biological Chemistry.

Androgen Receptor Coregulators in Prostate Cancer

Chawnshang Chang, H. Miyamoto, Mujib M. Rahman, 2004, Clinical Cancer Research.

Molecular basis for the antiandrogen withdrawal syndrome

Chawnshang Chang, H. Miyamoto, Mujib M. Rahman, 2004, Journal of cellular biochemistry.

Antitumor agents 222. Synthesis and anti-androgen activity of new diarylheptanoids.

Chawnshang Chang, K. Lee, Zhiyan Xiao, 2003, Bioorganic & medicinal chemistry.

Expression and Degradation of Androgen Receptor: Mechanism and Clinical Implication

Chawnshang Chang, Dong Kun Lee, 2003 .

Inactivation of androgen receptor coregulator ARA55 inhibits androgen receptor activity and agonist effect of antiandrogens in prostate cancer cells

Chawnshang Chang, H. Miyamoto, H. Lardy, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Isolation and Characterization of Androgen Receptor Mutant, AR(M749L), with Hypersensitivity to 17-β Estradiol Treatment*

T. Thin, Chawnshang Chang, Liang Wang, 2003, The Journal of Biological Chemistry.

The second largest subunit of RNA polymerase II interacts with and enhances transactivation of androgen receptor.

Chawnshang Chang, Dong Kun Lee, Mei Li, 2003, Biochemical and biophysical research communications.

Differential Modulation of Androgen Receptor-mediated Transactivation by Smad3 and Tumor Suppressor Smad4*

Chawnshang Chang, Wen-Lung Ma, Wen-Jye Lin, 2002, The Journal of Biological Chemistry.

Antitumor agents. 217. Curcumin analogues as novel androgen receptor antagonists with potential as anti-prostate cancer agents.

Chawnshang Chang, K. Lee, J. Ishida, 2002, Journal of medicinal chemistry.

Androgen receptor (AR) coregulators: an overview.

C. Heinlein, Chawnshang Chang, Chawnshang Chang, 2002, Endocrine reviews.

A Dominant-negative Mutant of Androgen Receptor Coregulator ARA54 Inhibits Androgen Receptor-mediated Prostate Cancer Growth*

Hong-Chiang Chang, S. Yeh, Chawnshang Chang, 2002, The Journal of Biological Chemistry.

Androgen Receptor Interacting Proteins: Co-Activators And Co-Repressors

C. Heinlein, Chawnshang Chang, E. Sampson, 2002 .

Androgens and Androgen Receptor

Chawnshang Chang, 2002, Springer US.

From Androgen Receptor to the General Transcription Factor TFIIH

Chawnshang Chang, Dong Kun Lee, H. Duan, 2000, The Journal of Biological Chemistry.

Cloning and Characterization of Human Prostate Coactivator ARA54, a Novel Protein That Associates with the Androgen Receptor*

S. Yeh, Chawnshang Chang, Hong-Yo Kang, 1999, The Journal of Biological Chemistry.

Suppression of androgen receptor transactivation and prostate cancer cell growth by heterogeneous nuclear ribonucleoprotein A1 via interaction with androgen receptor coregulator ARA54.

P. di Sant'Agnese, S. Yeh, Chawnshang Chang, 2007, Endocrinology.

Transgelin functions as a suppressor via inhibition of ARA54-enhanced androgen receptor transactivation and prostate cancer cell growth.

Jorge L Yao, Yu-Jia Chang, P. di Sant'Agnese, 2007, Molecular endocrinology.

Acetylation of Androgen Receptor Enhances Coactivator Binding and Promotes Prostate Cancer Cell Growth

E. Rosen, O. Jänne, D. Di Vizio, 2003, Molecular and Cellular Biology.

Promotes Prostate Cancer Cell Growth Enhances Coactivator Binding and Acetylation of Androgen Receptor

E. Rosen, O. Jänne, D. Di Vizio, 2003 .

Receptor-negative Prostate Cancer Cells Antiandrogen Hydroxyflutamide in Androgen Activation of Mitogen-activated Protein Kinase Pathway by the Updated

E. Messing, G. Wilding, Jiaoti Huang, 2002 .

Activation of Mitogen-activated Protein Kinase Pathway by the Antiandrogen Hydroxyflutamide in Androgen Receptor-negative Prostate Cancer Cells 1

E. Messing, G. Wilding, Jiaoti Huang, 2002 .

Cryptotanshinone down‐regulates androgen receptor signaling by modulating lysine‐specific demethylase 1 function

Chawnshang Chang, Ching-Yuan Wu, Ko-en Huang, 2012, International journal of cancer.

The roles of androgen receptors and androgen-binding proteins in nongenomic androgen actions.

C. Heinlein, Chawnshang Chang, Chawnshang Chang, 2002, Molecular endocrinology.

An estrogen receptor positive MCF-7 clone that is resistant to antiestrogens and estradiol

Chawnshang Chang, D. Wolf, J. Yingling, 1992, Molecular and Cellular Endocrinology.

Mice lacking TR4 nuclear receptor develop mitochondrial myopathy with deficiency in complex I.

M. Massett, H. Uno, Chawnshang Chang, 2011, Molecular endocrinology.

Infertility with defective spermatogenesis and steroidogenesis in male mice lacking androgen receptor in Leydig cells

S. Yeh, Chawnshang Chang, S. Altuwaijri, 2007, Endocrine.

Androgen receptor corepressors: An overview

Chawnshang Chang, Liang Wang, Cheng‐Lung Hsu, 2005, The Prostate.

AndrogenReceptorCorepressors : AnOverview

Chawnshang Chang, Liang Wang, Cheng‐Lung Hsu, 2004 .

Androgen receptor roles in the development of benign prostate hyperplasia.

Chawnshang Chang, Wen-Jye Lin, K. Izumi, 2013, The American journal of pathology.

Isolation and Characterization of ARA160 as the First Androgen Receptor N-terminal-associated Coactivator in Human Prostate Cells*

Chawnshang Chang, P. Hsiao, 1999, The Journal of Biological Chemistry.

Androgen receptor roles in spermatogenesis and fertility: lessons from testicular cell-specific androgen receptor knockout mice.

S. Yeh, Chawnshang Chang, C. Tzeng, 2009, Endocrine reviews.

TR4 nuclear receptor promotes clear cell renal cell carcinoma (ccRCC) vasculogenic mimicry (VM) formation and metastasis via altering the miR490-3p/vimentin signals

S. Yeh, Chawnshang Chang, Gonghui Li, 2018, Oncogene.

Androgen receptor promotes renal cell carcinoma (RCC) vasculogenic mimicry (VM) via altering TWIST1 nonsense-mediated decay through lncRNA-TANAR

S. Yeh, Jialin Meng, Chawnshang Chang, 2020, bioRxiv.

Infertility with defective spermatogenesis and hypotestosteronemia in male mice lacking the androgen receptor in Sertoli cells.

S. Yeh, Chawnshang Chang, S. Yeh, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Modulation of the retinoic acid-induced cell apoptosis and differentiation by the human TR4 orphan nuclear receptor.

Chawnshang Chang, B. Bao, Yi-Fen Lee, 2004, Biochemical and biophysical research communications.

Negative Feedback Control of the Retinoid-Retinoic Acid/Retinoid X Receptor Pathway by the Human TR4 Orphan Receptor, a Member of the Steroid Receptor Superfamily*

Chawnshang Chang, J. Burbach, Yi-Fen Lee, 1998, The Journal of Biological Chemistry.

Androgen receptor (AR) pathophysiological roles in androgen-related diseases in skin, bone/muscle, metabolic syndrome and neuron/immune systems: lessons learned from mice lacking AR in specific cells

S. Yeh, Chawnshang Chang, Soo Ok Lee, 2013, Nuclear receptor signaling.

Androgen Receptor Roles in Insulin Resistance and Obesity in Males: The Linkage of Androgen-Deprivation Therapy to Metabolic Syndrome

Hung-Yun Lin, S. Yeh, Chawnshang Chang, 2014, Diabetes.

Androgen receptor in sertoli cell is essential for germ cell nursery and junctional complex formation in mouse testes.

P. di Sant'Agnese, J. Ni, S. Yeh, 2006, Endocrinology.

Androgen Receptor Promotes Hepatitis B Virus–Induced Hepatocarcinogenesis Through Modulation of Hepatitis B Virus RNA Transcription

Y. Hung, S. Yeh, Chawnshang Chang, 2010, Science Translational Medicine.

Androgen receptor in human prostate cancer-associated fibroblasts promotes prostate cancer epithelial cell growth and invasion

S. Yeh, Chawnshang Chang, Dian-dong Yang, 2013, Medical Oncology.

Expression of androgen and oestrogen receptors and its prognostic significance in urothelial neoplasm of the urinary bladder

E. Messing, G. Netto, S. Yeh, 2012, BJU international.

Recruited mast cells in the tumor microenvironment enhance bladder cancer metastasis via modulation of ERβ/CCL2/CCR2 EMT/MMP9 signals

S. Yeh, Chawnshang Chang, Lei Li, 2015, Oncotarget.

Promotion of bladder cancer development and progression by androgen receptor signals.

E. Messing, S. Yeh, Chawnshang Chang, 2007, Journal of the National Cancer Institute.

Infiltrating macrophages promote prostate tumorigenesis via modulating androgen receptor-mediated CCL4-STAT3 signaling.

Chawnshang Chang, H. Miyamoto, Lei Li, 2013, Cancer research.

Expression of Human Prostatic Acid Phosphatase Correlates with Androgen-stimulated Cell Proliferation in Prostate Cancer Cell Lines*

A. Schönthal, Chawnshang Chang, Ming-Fong Lin, 1998, The Journal of Biological Chemistry.

Mechanisms and clinical relevance of androgens and androgen receptor actions.

Chawnshang Chang, Ko-en Huang, Hong-Yo Kang, 2003, Chang Gung medical journal.

Human Checkpoint Protein hRad9 Functions as a Negative Coregulator To Repress Androgen Receptor Transactivation in Prostate Cancer Cells

J. Ni, S. Yeh, P. Keng, 2004, Molecular and Cellular Biology.

Defects of prostate development and reproductive system in the estrogen receptor-alpha null male mice.

E. Messing, S. Radovick, Ming Chen, 2009, Endocrinology.

A mouse model of liver injury to evaluate paracrine and endocrine effects of bone marrow mesenchymal stem cells.

Chawnshang Chang, Chiung-Kuei Huang, Soo Ok Lee, 2014, Methods in molecular biology.

Enhancement of gene transactivation activity of androgen receptor by hepatitis B virus X protein.

Chawnshang Chang, J. Ou, Yanyan Zheng, 2007, Virology.

Suppression of Hepatitis B Virus Core Promoter by the Nuclear Orphan Receptor TR4*

Chawnshang Chang, S. Altuwaijri, S. Yeh, 2003, The Journal of Biological Chemistry.

Androgen and androgen receptor signals jamming monocyte/macrophage functions in premalignant phase of livers

L. Jeng, Chawnshang Chang, Wen-Lung Ma, 2012 .

Susceptibility to autoimmunity and B cell resistance to apoptosis in mice lacking androgen receptor in B cells.

A. Bottaro, Hong-Chiang Chang, S. Yeh, 2009, Molecular endocrinology.

Structure and Intranuclear Dynamics of Androgen Receptors

Chawnshang Chang, R. Hiipakka, S. Liao, 1989 .

ASC-J9® increases the bladder cancer chemotherapy efficacy via altering the androgen receptor (AR) and NF-κB survival signals

E. Messing, S. Yeh, Chawnshang Chang, 2019, Journal of experimental & clinical cancer research : CR.

LncRNA-SARCC suppresses renal cell carcinoma (RCC) progression via altering the androgen receptor(AR)/miRNA-143-3p signals

Chawnshang Chang, W. Zhai, Mingchao Wang, 2017, Cell Death and Differentiation.

Androgen receptor (AR)/miR-520f-3p/SOX9 signaling is involved in altering hepatocellular carcinoma (HCC) cell sensitivity to the Sorafenib therapy under hypoxia via increasing cancer stem cells phenotype.

S. Yeh, Chawnshang Chang, Yin Sun, 2019, Cancer letters.

TR4 nuclear receptor functions as a tumor suppressor for prostate tumorigenesis via modulation of DNA damage/repair system.

Chawnshang Chang, H. Miyamoto, Dong-Rong Yang, 2014, Carcinogenesis.

The expression and actions of androgen receptor in upper urinary tract urothelial carcinoma (UUTUC) tissues and the primary cultured cells

E. Messing, S. Yeh, Chawnshang Chang, 2013, Endocrine.

Androgen receptor‐regulated circFNTA activates KRAS signaling to promote bladder cancer invasion

S. Yeh, Y. Tsai, Chawnshang Chang, 2020, EMBO reports.

Infiltrating T cells promote prostate cancer metastasis via modulation of FGF11→miRNA‐541→androgen receptor (AR)→MMP9 signaling

Hong-Chiang Chang, S. Yeh, Chawnshang Chang, 2015, Molecular oncology.

Decreased tumorigenesis and mortality from bladder cancer in mice lacking urothelial androgen receptor.

Xue-Ru Wu, Chawnshang Chang, H. Miyamoto, 2013, The American journal of pathology.

Androgen receptor is a new potential therapeutic target for the treatment of hepatocellular carcinoma.

S. Yeh, Chawnshang Chang, Y. Jou, 2008, Gastroenterology.

ASC-J9 ameliorates spinal and bulbar muscular atrophy phenotype via degradation of androgen receptor

G. Sobue, S. Yeh, Chawnshang Chang, 2007, Nature Medicine.

Repression of Glucagon Gene Transcription by Peroxisome Proliferator-activated Receptor γ through Inhibition of Pax6 Transcriptional Activity*

C. Heinlein, Chawnshang Chang, C. Dellas, 2002, The Journal of Biological Chemistry.

LncRNA PCAT1 activates AKT and NF-κB signaling in castration-resistant prostate cancer by regulating the PHLPP/FKBP51/IKKα complex

Chawnshang Chang, N. Jiang, Y. Niu, 2019, Nucleic acids research.

Tumor suppressor PAX6 functions as androgen receptor Co‐repressor to inhibit prostate cancer growth

S. Yeh, Chawnshang Chang, Chao-Cheng Huang, 2010, The Prostate.

The miR-367-3p Increases Sorafenib Chemotherapy Efficacy to Suppress Hepatocellular Carcinoma Metastasis through Altering the Androgen Receptor Signals

Chawnshang Chang, Gonghui Li, Xiujun Cai, 2016, EBioMedicine.

Phosphorylation‐dependent ubiquitylation and degradation of androgen receptor by Akt require Mdm2 E3 ligase

Chawnshang Chang, Hui-Kuan Lin, S. Altuwaijri, 2002, The EMBO journal.

NF-kappaB regulates androgen receptor expression and prostate cancer growth.

W. Gerald, H. Scher, H. Lilja, 2009, The American journal of pathology.

Targeting the stromal androgen receptor in primary prostate tumors at earlier stages

S. Yeh, Chawnshang Chang, S. Altuwaijri, 2008, Proceedings of the National Academy of Sciences.

Androgen receptor is a tumor suppressor and proliferator in prostate cancer

Jorge Yao, Edward M Messing, William A Ricke, 2008, Proceedings of the National Academy of Sciences.

TR4 nuclear receptor enhances prostate cancer initiation via altering the stem cell population and EMT signals in the PPARG-deleted prostate cells

Chawnshang Chang, H. Miyamoto, Dong-Rong Yang, 2015, Oncoscience.

Differential roles of PPARγ vs TR4 in prostate cancer and metabolic diseases.

Chawnshang Chang, Dong-Rong Yang, Gonghui Li, 2014, Endocrine-related cancer.

Identification of ARA70 as a Ligand-enhanced Coactivator for the Peroxisome Proliferator-activated Receptor γ*

S. Yeh, C. Heinlein, Chawnshang Chang, 1999, The Journal of Biological Chemistry.

Proteasome Activity Is Required for Androgen Receptor Transcriptional Activity via Regulation of Androgen Receptor Nuclear Translocation and Interaction with Coregulators in Prostate Cancer Cells*

Chawnshang Chang, Hui-Kuan Lin, S. Altuwaijri, 2002, The Journal of Biological Chemistry.

The miR-361-3p increases enzalutamide (Enz) sensitivity via targeting the ARv7 and MKNK2 to better suppress the Enz-resistant prostate cancer

Chawnshang Chang, Y. Niu, Min Tang, 2020, Cell Death & Disease.

Identification of a new androgen receptor (AR) co‐regulator BUD31 and related peptides to suppress wild‐type and mutated AR‐mediated prostate cancer growth via peptide screening and X‐ray structure analysis

Jai-Shin Liu, Chawnshang Chang, S. Yeh, 2014, Molecular oncology.

The selective inhibitory effect of a synthetic tanshinone derivative on prostate cancer cells

S. Yeh, Y. Tsai, Chawnshang Chang, 2012, The Prostate.

Cryptotanshinone suppresses androgen receptor-mediated growth in androgen dependent and castration resistant prostate cancer cells.

S. Yeh, Chawnshang Chang, Defeng Xu, 2012, Cancer letters.

ASC-J9 suppresses castration-resistant prostate cancer growth through degradation of full-length and splice variant androgen receptors.

H. Kung, S. Yeh, Chawnshang Chang, 2012, Neoplasia.

Roles of testicular orphan nuclear receptors 2 and 4 in early embryonic development and embryonic stem cells.

Chawnshang Chang, C. Shyr, Ko-en Huang, 2009, Endocrinology.

Targeting androgen receptor (AR) with antiandrogen Enzalutamide increases prostate cancer cell invasion yet decreases bladder cancer cell invasion via differentially altering the AR/circRNA-ARC1/miR-125b-2-3p or miR-4736/PPARγ/MMP-9 signals

S. Yeh, Chawnshang Chang, C. Feng, 2021, Cell Death & Differentiation.

Differential Roles of Androgen Receptor in Prostate Development and Cancer Progression

S. Yeh, Chawnshang Chang, H. Miyamoto, 2009 .

Suppression of Androgen Receptor-mediated Transactivation and Cell Growth by the Glycogen Synthase Kinase 3β in Prostate Cells*

Chawnshang Chang, Lin Yang, Hui-Kuan Lin, 2004, Journal of Biological Chemistry.

ARA67/PAT1 Functions as a Repressor To Suppress Androgen Receptor Transactivation

S. Yeh, Chawnshang Chang, Yanqing Zhang, 2004, Molecular and Cellular Biology.

Modulation of androgen receptor transactivation by gelsolin: a newly identified androgen receptor coregulator.

Hong-Chiang Chang, S. Yeh, K. Aozasa, 2003, Cancer research.

Molecular communication between androgen receptor and general transcription machinery

Chawnshang Chang, Dong Kun Lee, 2003, The Journal of Steroid Biochemistry and Molecular Biology.

Supervillin associates with androgen receptor and modulates its transcriptional activity

S. Yeh, Chawnshang Chang, H. Ting, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Identification and Characterization of a Novel Androgen Receptor Coregulator ARA267-α in Prostate Cancer Cells*

S. Yeh, Chawnshang Chang, Liang Wang, 2001, The Journal of Biological Chemistry.

Androgen Receptor Interacts with the Positive Elongation Factor P-TEFb and Enhances the Efficiency of Transcriptional Elongation*

Chawnshang Chang, Dong Kun Lee, H. Duan, 2001, The Journal of Biological Chemistry.

The Linkage of Kennedy’s Neuron Disease to ARA24, the First Identified Androgen Receptor Polyglutamine Region-associated Coactivator*

Chawnshang Chang, P. Hsiao, D. Lin, 1999, The Journal of Biological Chemistry.

Cloning and Characterization of Androgen Receptor Coactivator, ARA55, in Human Prostate*

S. Inui, Hong-Chiang Chang, S. Yeh, 1999, The Journal of Biological Chemistry.

ASC-J9(®), and not Casodex or Enzalutamide, suppresses prostate cancer stem/progenitor cell invasion via altering the EZH2-STAT3 signals.

S. Yeh, Chawnshang Chang, Lei Li, 2016, Cancer letters.

R-2HG downregulates ERα to inhibit cholangiocarcinoma via the FTO/m6A-methylated ERα/miR16-5p/YAP1 signal pathway

S. Yeh, Chawnshang Chang, Yuan Gao, 2021, Molecular therapy oncolytics.

Evidence of TGF-β1 mediated epithelial-mesenchymal transition in immortalized benign prostatic hyperplasia cells

Chawnshang Chang, Jie Jin, Shuai Hu, 2014, Molecular membrane biology.

The Differential Effects of Anti-Diabetic Thiazolidinedione on Prostate Cancer Progression Are Linked to the TR4 Nuclear Receptor Expression Status12

Hong-Chiang Chang, Chawnshang Chang, H. Miyamoto, 2015, Neoplasia.

Androgen Receptor Acetylation Governs trans Activation and MEKK1-Induced Apoptosis without Affecting In Vitro Sumoylation and trans-Repression Function

S. Fuqua, O. Jänne, R. Hay, 2002, Molecular and Cellular Biology.

Androgen receptor and immune inflammation in benign prostatic hyperplasia and prostate cancer.

Chawnshang Chang, Lei Li, K. Izumi, 2014, Clinical investigation.

Stage dependent and androgen inductive expression of orphan receptor TR4 in rat testis.

Chawnshang Chang, Lin Yang, X. Mu, 2006, Biochemical and biophysical research communications.

TR4 nuclear receptor functions as a fatty acid sensor to modulate CD36 expression and foam cell formation

J. Ni, Chawnshang Chang, Shaozhen Xie, 2009, Proceedings of the National Academy of Sciences.

Recent advances in the TR2 and TR4 orphan receptors of the nuclear receptor superfamily

Chawnshang Chang, Han-Jung Lee, Yi-Fen Lee, 2002, The Journal of Steroid Biochemistry and Molecular Biology.

Endothelial Cells Enhance Prostate Cancer Metastasis via IL-6→Androgen Receptor→TGF-β→MMP-9 Signals

Xiaohai Wang, S. Yeh, Chawnshang Chang, 2013, Molecular Cancer Therapeutics.

Activin A Enhances Prostate Cancer Cell Migration Through Activation of Androgen Receptor and Is Overexpressed in Metastatic Prostate Cancer

Chang-Yi Hsieh, Hsuan-Ying Huang, Chawnshang Chang, 2009, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Loss of stromal androgen receptor leads to suppressed prostate tumourigenesis via modulation of pro-inflammatory cytokines/chemokines

S. Yeh, Chawnshang Chang, Chiung-Kuei Huang, 2012, EMBO molecular medicine.

Concise Review: Androgen Receptor Differential Roles in Stem/Progenitor Cells Including Prostate, Embryonic, Stromal, and Hematopoietic Lineages

Chawnshang Chang, Chiung-Kuei Huang, Soo Ok Lee, 2014, Stem cells.

Urethral Dysfunction in Female Mice with Estrogen Receptor β Deficiency

Yung-Hsiang Chen, Wen-Tsong Hsieh, Yu-Ning Lin, 2014, PloS one.

Regulation of interleukin‐6‐mediated PI3K activation and neuroendocrine differentiation by androgen signaling in prostate cancer LNCaP cells

P. di Sant'Agnese, J. Ni, Chawnshang Chang, 2004, The Prostate.

Androgen-deprivation therapy with enzalutamide enhances prostate cancer metastasis via decreasing the EPHB6 suppressor expression.

S. Yeh, Chawnshang Chang, Jiaqi Chen, 2017, Cancer letters.

C1QBP Regulates YBX1 to Suppress the Androgen Receptor (AR)-Enhanced RCC Cell Invasion

Chawnshang Chang, Y. Niu, Dan Yue, 2017, Neoplasia.

Suppressing BCL-XL increased the high dose androgens therapeutic effect to better induce the Enzalutamide-resistant prostate cancer autophagic cell death

Chawnshang Chang, Yin Sun, Bosen You, 2021, Cell death & disease.

Targeting fatty acid synthase with ASC‐J9 suppresses proliferation and invasion of prostate cancer cells

S. Yeh, Chawnshang Chang, Y. Niu, 2016, Molecular carcinogenesis.

Testicular orphan nuclear receptor 4-associated protein 16 promotes non-small cell lung carcinoma by activating estrogen receptor β and blocking testicular orphan nuclear receptor 2

Chawnshang Chang, Shaolei Li, Yue Yang, 2012, Oncology reports.

Hormonal Therapy for Prostate Cancer: Clinical and Experimental Evidence

Chawnshang Chang, H. Miyamoto, 2022 .

Recruited T cells promote the bladder cancer metastasis via up-regulation of the estrogen receptor β/IL-1/c-MET signals.

E. Messing, S. Yeh, Chawnshang Chang, 2018, Cancer letters.

Targeting the androgen receptor with siRNA promotes prostate cancer metastasis through enhanced macrophage recruitment via CCL2/CCR2-induced STAT3 activation

Chawnshang Chang, Lei Li, Wen-Jye Lin, 2013, EMBO molecular medicine.

Tumor microenvironment B cells increase bladder cancer metastasis via modulation of the IL-8/androgen receptor (AR)/MMPs signals

S. Yeh, Chawnshang Chang, L. Qi, 2015, Oncotarget.

Regulation of Gene Expression in the Prostate

R. Matusik, J. Davie, Chawnshang Chang, 1991 .

Anti‐androgen enzalutamide enhances prostate cancer neuroendocrine (NE) differentiation via altering the infiltrated mast cells → androgen receptor (AR) → miRNA32 signals

Hong-Chiang Chang, S. Yeh, D. He, 2015, Molecular oncology.

The Expanded Poly-Q Length Within AR and AR Coregulator AIB1 and Their Clinical Implications

Chawnshang Chang, A. Hsing, Z. Culig, 2002 .

LncRNA-p21 alters the antiandrogen enzalutamide-induced prostate cancer neuroendocrine differentiation via modulating the EZH2/STAT3 signaling

Liang Cheng, S. Yeh, Chawnshang Chang, 2019, Nature Communications.

ADT with antiandrogens in prostate cancer induces adverse effect of increasing resistance, neuroendocrine differentiation and tumor metastasis.

S. Yeh, Chawnshang Chang, Y. Niu, 2018, Cancer letters.

AUTHOR COPY ONLY Suppressor role of androgen receptor in proliferation of prostate basal epithelial and progenitor cells

S. Yeh, Chawnshang Chang, Chiung-Kuei Huang, 2012 .

of prostate basal epithelial and progenitor cells

S. Yeh, Chawnshang Chang, Chiung-Kuei Huang, 2012 .

Androgen receptor modulates metastatic routes of VHL wild-type clear cell renal cell carcinoma in an oxygen-dependent manner

Xin Ma, Donglai Shen, Xu Zhang, 2020, Oncogene.

Immune Suppressive Activity and Lack of T Helper Differentiation Are Differentially Regulated in Natural Regulatory T Cells1

Chawnshang Chang, Wei-ping Zeng, Jiann-jyh Lai, 2009, The Journal of Immunology.

Anabolic androgens affect the competitive interactions in cell migration and adhesion between normal mouse urothelial cells and urothelial carcinoma cells.

Chawnshang Chang, C. Shyr, Chi-Cheng Chen, 2014, Biochemical and biophysical research communications.

Infiltrating neutrophils promote renal cell carcinoma (RCC) proliferation via modulating androgen receptor (AR) → c-Myc signals.

S. Yeh, D. He, Chawnshang Chang, 2015, Cancer letters.

Feedback Regulation between Orphan Nuclear Receptor TR2 and Human Papilloma Virus Type 16

Chawnshang Chang, X. Mu, D. Lin, 2001, The Journal of Biological Chemistry.

Induction of Androgen Receptor Expression by Phosphatidylinositol 3-Kinase/Akt Downstream Substrate, FOXO3a, and Their Roles in Apoptosis of LNCaP Prostate Cancer Cells*

J. Ni, Chawnshang Chang, Lin Yang, 2005, Journal of Biological Chemistry.

Neurotensin and its receptors mediate neuroendocrine transdifferentiation in prostate cancer

Chawnshang Chang, Yinghao Sun, N. Jiang, 2019, Oncogene.

Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptor

S. Yeh, Chawnshang Chang, Hui-Kuan Lin, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Stromal androgen receptor roles in the development of normal prostate, benign prostate hyperplasia, and prostate cancer.

Hong-Chiang Chang, Chawnshang Chang, Y. Niu, 2015, The American journal of pathology.

TR4 Nuclear Receptor Alters the Prostate Cancer CD133+ Stem/Progenitor Cell Invasion via Modulating the EZH2-Related Metastasis Gene Expression

Hong-Chiang Chang, Chawnshang Chang, Dong-rong Yang, 2015, Molecular Cancer Therapeutics.

Infiltrating mast cells enhance prostate cancer invasion via altering LncRNA-HOTAIR/PRC2-androgen receptor (AR)-MMP9 signals and increased stem/progenitor cell population

S. Yeh, D. He, Chawnshang Chang, 2015, Oncotarget.

Nongenomic Androgen Action

C. Heinlein, Chawnshang Chang, 2002 .

Androgen receptor (AR) suppresses miRNA-145 to promote renal cell carcinoma (RCC) progression independent of VHL status

Chawnshang Chang, Lei Li, Yuan-Hua Chen, 2015, Oncotarget.

Natural killer cells suppress enzalutamide resistance and cell invasion in the castration resistant prostate cancer via targeting the androgen receptor splicing variant 7 (ARv7).

S. Yeh, Chawnshang Chang, Lei Li, 2017, Cancer letters.

Targeting AR-Beclin 1 complex-modulated growth factor signaling increases the antiandrogen Enzalutamide sensitivity to better suppress the castration-resistant prostate cancer growth.

C. Liang, Jialin Meng, Meng Zhang, 2019, Cancer letters.

ASC-J9(®) suppresses castration resistant prostate cancer progression via degrading the enzalutamide-induced androgen receptor mutant AR-F876L.

Chawnshang Chang, Lei Li, Rong-hao Wang, 2016, Cancer letters.

Inhibition of the Akt, cyclooxygenase‐2, and matrix metalloproteinase‐9 pathways in combination with androgen deprivation therapy: Potential therapeutic approaches for prostate cancer

E. Messing, Chawnshang Chang, S. Altuwaijri, 2005, Molecular carcinogenesis.

Does androgen deprivation improve treatment outcomes in patients with low-risk and intermediate-risk prostate cancer?

E. Messing, Chawnshang Chang, H. Miyamoto, 2005, Nature Clinical Practice Oncology.

Androgen receptor (AR) positive vs negative roles in prostate cancer cell deaths including apoptosis, anoikis, entosis, necrosis and autophagic cell death.

Chawnshang Chang, Y. Niu, Soo Ok Lee, 2014, Cancer treatment reviews.

Targeting the radiation-induced TR4 nuclear receptor-mediated QKI/circZEB1/miR-141-3p/ZEB1 signaling increases prostate cancer radiosensitivity.

S. Yeh, Yuhchyau Chen, Chawnshang Chang, 2020, Cancer letters.

Androgen receptor (AR) NH2- and COOH-terminal interactions result in the differential influences on the AR-mediated transactivation and cell growth.

Hong-Chiang Chang, S. Yeh, Chawnshang Chang, 2005, Molecular endocrinology.

Targeting estrogen/estrogen receptor alpha enhances Bacillus Calmette-Guérin efficacy in bladder cancer

E. Messing, S. Yeh, Chawnshang Chang, 2016, Oncotarget.

Antiandrogen Therapy with Hydroxyflutamide or Androgen Receptor Degradation Enhancer ASC-J9 Enhances BCG Efficacy to Better Suppress Bladder Cancer Progression

E. Messing, S. Yeh, Chawnshang Chang, 2015, Molecular Cancer Therapeutics.

A Festschrift in Honor of Edward M. Messing, MD, FACS

P. Okunieff, D. Rubens, R. Brasacchio, 2018, Bladder cancer.

Oxidative stress stimulates testicular orphan receptor 4 through forkhead transcription factor forkhead box O3a.

Chawnshang Chang, Zhao-dian Chen, Shaozhen Xie, 2008, Endocrinology.

Targeting circDGKD Intercepts TKI’s Effects on Up-Regulation of Estrogen Receptor β and Vasculogenic Mimicry in Renal Cell Carcinoma

J. Qi, Xiaohui Cui, S. Yeh, 2022, Cancers.

New therapy with ASC-J9® to suppress the prostatitis via altering the cytokine CCL2 signals

Hong-Chiang Chang, S. Yeh, Chawnshang Chang, 2016, Oncotarget.

Androgen receptor increases hematogenous metastasis yet decreases lymphatic metastasis of renal cell carcinoma

Xin Ma, Xintao Li, Yu Gao, 2017, Nature Communications.

Estrogen receptor β promotes renal cell carcinoma progression via regulating LncRNA HOTAIR-miR-138/200c/204/217 associated CeRNA network

S. Yeh, Chawnshang Chang, Chiuan-Ren Yeh, 2018, Oncogene.

Targeted Inactivation of Testicular Nuclear Orphan Receptor 4 Delays and Disrupts Late Meiotic Prophase and Subsequent Meiotic Divisions of Spermatogenesis

Chawnshang Chang, Yi-Fen Lee, C. Shyr, 2004, Molecular and Cellular Biology.

Activation of TR4 orphan nuclear receptor gene promoter by cAMP/PKA and C/EBP signaling

Hung-Yun Lin, Chawnshang Chang, Hung-Yun Lin, 2009, Endocrine.

Loss of TR4 Orphan Nuclear Receptor Reduces Phosphoenolpyruvate Carboxykinase–Mediated Gluconeogenesis

Chawnshang Chang, Hung-Yun Lin, J. Sparks, 2007, Diabetes.

Stearoyl CoA desaturase (SCD) facilitates proliferation of prostate cancer cells through enhancement of androgen receptor transactivation

Chawnshang Chang, Sung-Soo Park, Seung‐Jin Kim, 2011, Molecules and cells.

The p53/Retinoblastoma-mediated Repression of Testicular Orphan Receptor-2 in the Rhesus Monkey with Cryptorchidism*

Chawnshang Chang, X. Mu, Eungseok Kim, 2000, The Journal of Biological Chemistry.

Involvement of interleukin-6 and androgen receptor signaling in pancreatic cancer.

Tatsuo Kanda, Fumio Imazeki, Osamu Yokosuka, 2010, Genes & cancer.

Temporal and Spatial Changes of Histone 3 K4 Dimethylation at the IFN-γ Gene during Th1 and Th2 Cell Differentiation1

Chawnshang Chang, J. Kobie, Wei-ping Zeng, 2007, The Journal of Immunology.

p53 Is a Mediator for Radiation-repressed Human TR2 Orphan Receptor Expression in MCF-7 Cells, a New Pathway from Tumor Suppressor to Member of the Steroid Receptor Superfamily*

Chawnshang Chang, D. Lin, 1996, The Journal of Biological Chemistry.

Increased Chemosensitivity via Targeting Testicular Nuclear Receptor 4 (TR4)-Oct4-Interleukin 1 Receptor Antagonist (IL1Ra) Axis in Prostate Cancer CD133+ Stem/Progenitor Cells to Battle Prostate Cancer*

Yuhchyau Chen, Chawnshang Chang, Chiung-Kuei Huang, 2013, The Journal of Biological Chemistry.

The genomic structure and chromosomal location of the human TR2 orphan receptor, a member of the steroid receptor superfamily

Chawnshang Chang, D. Lin, Shi-qi Wu, 1998, Endocrine.

Thyroid hormone direct repeat 4 response element is a positive regulatory element for the human TR2 orphan receptor, a member of steroid receptor superfamily

Chawnshang Chang, H. Pan, 1998, Molecular and Cellular Biochemistry.

Targeting the estrogen receptor alpha (ERα)-mediated circ-SMG1.72/miR-141-3p/Gelsolin signaling to better suppress the HCC cell invasion

S. Yeh, Chawnshang Chang, Yin Sun, 2020, Oncogene.

The expression and evaluation of androgen receptor in human renal cell carcinoma.

S. Yeh, D. He, Chawnshang Chang, 2014, Urology.

Androgens and androgen receptor : mechanisms, functions, and clinical applications

Chawnshang Chang, 2002 .

Epidermal growth factor enhances androgen receptor‑mediated bladder cancer progression and invasion via potentiation of AR transactivation.

Chawnshang Chang, Wei-Min Chuang, Wen-Lung Ma, 2013, Oncology reports.

Identification of a Novel Testicular Orphan Receptor-4 (TR4)-associated Protein as Repressor for the Selective Suppression of TR4-mediated Transactivation*

Chawnshang Chang, Wen-Jye Lin, Yue Yang, 2003, The Journal of Biological Chemistry.

Targeting androgen receptor in bone marrow mesenchymal stem cells leads to better transplantation therapy efficacy in liver cirrhosis

Chawnshang Chang, Chiung-Kuei Huang, Wen-Lung Ma, 2013, Hepatology.

Androgen receptor roles in hepatocellular carcinoma, fatty liver, cirrhosis and hepatitis.

S. Yeh, Chawnshang Chang, Wen-Lung Ma, 2014, Endocrine-related cancer.

Polymorphic CAG/CAA repeat length in the AIB1/SRC-3 gene and prostate cancer risk: a population-based case-control study.

F. Mostofi, A. Chokkalingam, I. Sesterhenn, 2002, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

Growth retardation and abnormal maternal behavior in mice lacking testicular orphan nuclear receptor 4.

H. Uno, C. Heinlein, Chawnshang Chang, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Embryonic and fetal β‐globin gene repression by the orphan nuclear receptors, TR2 and TR4

J. D. Engel, Xia Jiang, K. Tanimoto, 2007, The EMBO journal.

Disruption of TR4 Orphan Nuclear Receptor Reduces the Expression of Liver Apolipoprotein E/C-I/C-II Gene Cluster*

Chawnshang Chang, Shaozhen Xie, S. Yeh, 2003, Journal of Biological Chemistry.

Disruption of TR 4 Orphan Nuclear Receptor Reduces the Expression of Liver Apolipoprotein E / CI / CII Gene Cluster *

Chawnshang Chang, Shaozhen Xie, S. Yeh, 2003 .

Spermatogenesis and Testis Development Are Normal in Mice Lacking Testicular Orphan Nuclear Receptor 2

Chawnshang Chang, C. Shyr, K. Platt, 2002, Molecular and Cellular Biology.

A Bidirectional Regulation between the TR2/TR4 Orphan Receptors (TR2/TR4) and the Ciliary Neurotrophic Factor (CNTF) Signaling Pathway*

Chawnshang Chang, Yi-Fen Lee, Susan M. Smith, 1998, The Journal of Biological Chemistry.

Induction of an intronic enhancer of the human ciliary neurotrophic factor receptor (CNTFRα) gene by the TR3 orphan receptor

Chawnshang Chang, Yi-Xun Liu, H. Uemura, 1998, Endocrine.

Identification of Direct Repeat 4 as a Positive Regulatory Element for the Human TR4 Orphan Receptor

Chawnshang Chang, J. Burbach, H. Pan, 1997, The Journal of Biological Chemistry.

Induction of the Intronic Enhancer of the Human Ciliary Neurotrophic Factor Receptor (CNTFRα) Gene by the TR4 Orphan Receptor

Chawnshang Chang, Susan M. Smith, W. Young, 1997, The Journal of Biological Chemistry.

Suppression of the Human Erythropoietin Gene Expression by the TR2 Orphan Receptor, a Member of the Steroid Receptor Superfamily (*)

Chawnshang Chang, W. Young, C. Shih, 1996, The Journal of Biological Chemistry.

Physiological Functions of TR2 and TR4 Orphan Nuclear Receptor

Chawnshang Chang, Shaozhen Xie, Yi-Fen Lee, 2010 .

Basic fibroblast growth factor in human prostate cancer cells.

Chawnshang Chang, G. Chodak, A. Li, 1992, Cancer research.

Generation and characterization of a complete null estrogen receptor α mouse using Cre/LoxP technology

S. Radovick, Ming Chen, S. Yeh, 2008, Molecular and Cellular Biochemistry.

Suppression of Gene Expression on the Simian Virus 40 Major Late Promoter by Human TR4 Orphan Receptor

Chawnshang Chang, J. Burbach, Han-Jung Lee, 1995, The Journal of Biological Chemistry.

Multiple Functions of the TR2-11 Orphan Receptor in Modulating Activation of Two Key Cis-acting Elements Involved in the Retinoic Acid Signal Transduction System (*)

Chawnshang Chang, W. Young, Tien-Min Lin, 1995, The Journal of Biological Chemistry.

Identification of Human TR2 Orphan Receptor Response Element in the Transcriptional Initiation Site of the Simian Virus 40 Major Late Promoter (*)

Chawnshang Chang, Han-Jung Lee, 1995, The Journal of Biological Chemistry.

Tissue prostate-specific antigen facilitates refractory prostate tumor progression via enhancing ARA70-regulated androgen receptor transactivation.

S. Yeh, Chawnshang Chang, S. Altuwaijri, 2008, Cancer research.

D5-Androstenediol is a natural hormone with androgenic activity in human prostate cancer cells

S. Yeh, Chawnshang Chang, H. Miyamoto, 1998 .

Preclinical study using circular RNA 17 and micro RNA 181c-5p to suppress the enzalutamide-resistant prostate cancer progression

Chawnshang Chang, Y. Niu, Yin Sun, 2019, Cell Death & Disease.

Increased hepatic steatosis and insulin resistance in mice lacking hepatic androgen receptor

S. Yeh, Chawnshang Chang, S. Altuwaijri, 2008, Hepatology.

Actin associated proteins function as androgen receptor coregulators: An implication of androgen receptor's roles in skeletal muscle

Chawnshang Chang, H. Ting, 2008, The Journal of Steroid Biochemistry and Molecular Biology.

Sorafenib with ASC‐J9® synergistically suppresses the HCC progression via altering the pSTAT3‐CCL2/Bcl2 signals

Chawnshang Chang, Wen-Lung Ma, Gonghui Li, 2016, International journal of cancer.

TR3 Orphan Nuclear Receptor Mediates Apoptosis through Up-regulating E2F1 in Human Prostate Cancer LNCaP Cells*

Chawnshang Chang, X. Mu, 2003, Journal of Biological Chemistry.

Neuronal Androgen Receptor Regulates Insulin Sensitivity via Suppression of Hypothalamic NF-κB–Mediated PTP1B Expression

S. Yeh, Chawnshang Chang, Hung-Yun Lin, 2013, Diabetes.

Evidence on the presence of secretin cells in the gastric antral and oxyntic mucosa

Chawnshang Chang, H. Pan, W. Chey, 2003, Regulatory Peptides.

The orphan nuclear receptor Nur77 regulates LKB1 localization and activates AMPK.

Qiao Wu, Tianwei Lin, Yuan Wang, 2012, Nature chemical biology.

Infiltrating bone marrow mesenchymal stem cells (BM-MSCs) increase prostate cancer cell invasion via altering the CCL5/HIF2α/androgen receptor signals

Chawnshang Chang, Lei Li, Soo Ok Lee, 2015, Oncotarget.

Increased Acetylation in the DNA-binding Domain of TR4 Nuclear Receptor by the Coregulator ARA55 Leads to Suppression of TR4 Transactivation*

J. Ni, Chawnshang Chang, Shaozhen Xie, 2011, The Journal of Biological Chemistry.

ASC-J9® suppresses prostate cancer cell invasion via altering the sumoylation-phosphorylation of STAT3.

Chawnshang Chang, Y. Niu, Gonghui Li, 2018, Cancer letters.

Metformin Inhibits Nuclear Receptor TR4–Mediated Hepatic Stearoyl-CoA Desaturase 1 Gene Expression With Altered Insulin Sensitivity

Chawnshang Chang, Hung-Yun Lin, J. Sparks, 2011, Diabetes.

TR4 orphan receptor crosstalks to chicken ovalbumin upstream protein-transcription factor and thyroid hormone receptor to induce the transcriptional activity of the human immunodeficiency virus type 1 long-terminal repeat

Chawnshang Chang, J. Burbach, San-bao Hwang, 1998, Endocrine.

Differential Regulation of Direct Repeat 3 Vitamin D3and Direct Repeat 4 Thyroid Hormone Signaling Pathways by the Human TR4 Orphan Receptor*

Chawnshang Chang, Wen-Jye Lin, Yi-Fen Lee, 1999, The Journal of Biological Chemistry.

Androgen receptor influences on body defense system via modulation of innate and adaptive immune systems: lessons from conditional AR knockout mice.

Chawnshang Chang, S. Altuwaijri, Kuang-Hsiang Chuang, 2012, The American journal of pathology.

The roles of testicular nuclear receptor 4 (TR4) in male fertility-priapism and sexual behavior defects in TR4 knockout mice

H. Uno, Chawnshang Chang, C. Meshul, 2011, Reproductive biology and endocrinology : RB&E.

The MAO inhibitors phenelzine and clorgyline revert enzalutamide resistance in castration resistant prostate cancer

Jun Luo, E. Antonarakis, S. Yeh, 2020, Nature Communications.

Androgen receptor signals regulate UDP‐glucuronosyltransferases in the urinary bladder: A potential mechanism of androgen‐induced bladder carcinogenesis

Chawnshang Chang, H. Miyamoto, K. Izumi, 2013, Molecular carcinogenesis.

The Wedelolactone Derivative Inhibits Estrogen Receptor-Mediated Breast, Endometrial, and Ovarian Cancer Cells Growth

S. Yeh, Chawnshang Chang, Chiuan-Ren Yeh, 2014, BioMed research international.

CREB/GSK-3β signaling pathway regulates the expression of TR4 orphan nuclear receptor gene

Chawnshang Chang, Sung-Soo Park, Seung‐Jin Kim, 2016, Molecular and Cellular Endocrinology.

Infiltrated pre-adipocytes increase prostate cancer metastasis via modulation of the miR-301a/androgen receptor (AR)/TGF-β1/Smad/MMP9 signals

Hong-Chiang Chang, S. Yeh, D. He, 2015, Oncotarget.

Title Targeting inflammatory cytokines-androgen receptor ( AR ) signaling withASC-J 9 ® to better battle prostate cancer progression

Chawnshang Chang, K. Izumi, 2017 .

Targeting inflammatory cytokines-androgen receptor (AR) signaling with ASC-J9® to better battle prostate cancer progression

Chawnshang Chang, K. Izumi, 2013, Oncoimmunology.

Abnormal cerebellar cytoarchitecture and impaired inhibitory signaling in adult mice lacking TR4 orphan nuclear receptor

H. Uno, Chawnshang Chang, C. Meshul, 2007, Brain Research.

Identification of the histamine H1 receptor gene as a differentially repressed target of the human TR2 orphan receptor

Chawnshang Chang, Yi-Fen Lee, H. Lee, 1999, Molecular and Cellular Biochemistry.

Expression of human AR cDNA driven by its own promoter results in mild promotion, but not suppression, of growth in human prostate cancer PC-3 cells.

Hong-Chiang Chang, Chawnshang Chang, S. Altuwaijri, 2007, Asian journal of andrology.

Targeting the TR4-induced RCC cells-derived exosomally initiated signaling increases Sunitinib efficacy

Chawnshang Chang, Yin Sun, Bosen You, 2022, bioRxiv.

Melatonin promotes sheep Leydig cell testosterone secretion in a co-culture with Sertoli cells.

Chawnshang Chang, Yi-Xun Liu, C. Cheng, 2018, Theriogenology.

Targeting androgen receptor as a new potential therapeutic approach to battle tobacco carcinogens-induced non-small cell lung cancer

Pan‐Chyr Yang, Cheng-Wen Wu, Chawnshang Chang, 2012, Journal of Translational Medicine.

Androgen receptor (AR) degradation enhancer ASC-J9® in an FDA-approved formulated solution suppresses castration resistant prostate cancer cell growth.

S. Yeh, Chawnshang Chang, Gonghui Li, 2018, Cancer letters.

Testicular orphan nuclear receptor 4 is associated with the radio‐sensitivity of prostate cancer

Chawnshang Chang, Bi-de Chen, Shicheng Yu, 2015, The Prostate.

BM-MSCs promote prostate cancer progression via the conversion of normal fibroblasts to cancer-associated fibroblasts

S. Yeh, Chawnshang Chang, Y. Niu, 2015, International journal of oncology.

TR2 and TR4 Orphan Nuclear Receptors: An Overview.

Hong-Chiang Chang, Chawnshang Chang, Dong-Rong Yang, 2017, Current topics in developmental biology.

Targeting newly identified ERβ/TGF‐β1/SMAD3 signals with the FDA‐approved anti‐estrogen Faslodex or an ERβ selective antagonist in renal cell carcinoma

Xu Zhang, S. Yeh, D. He, 2018, Molecular oncology.

Modulation of Estrogen Receptor-mediated Transactivation by Orphan Receptor TR4 in MCF-7 Cells*

Yueh-Chiang Hu, Chawnshang Chang, Yueh-Chiang Hu, 2002, The Journal of Biological Chemistry.

Androgen receptor mitigates postoperative disease progression of hepatocellular carcinoma by suppressing CD90+ populations and cell migration and by promoting anoikis in circulating tumor cells

L. Jeng, Chawnshang Chang, Wen-Lung Ma, 2016, Oncotarget.

Androgen receptor promotes the migration and invasion of upper urinary tract urothelial carcinoma cells through the upregulation of MMP-9 and COX-2.

Chawnshang Chang, Wen-Lung Ma, Caixia Zhang, 2013, Oncology reports.

Androgen effects on the solubility and conformational change of the androgen receptor in baculovirus expression system

Chawnshang Chang, Chihuei Wang, 1999, Molecular and Cellular Biochemistry.

Androgen and retinoic acid interaction in LNCaP cells, effects on cell proliferation and expression of retinoic acid receptors and epidermal growth factor receptor

Chawnshang Chang, R. Irwin, Hosea F. S. Huang, 2002, BMC Cancer.

The Androgen Receptor Co-regulator, ARA70

S. Inui, S. Yeh, Chawnshang Chang, 1998 .

cDNA Cloning, Antibody Production and Immunohistochemical Localization of the Androgen Receptor

Chawnshang Chang, H. Takeda, J. Kokontis, 1991 .

Characterization of New Members of the Steroid Receptor Super-Family

Chawnshang Chang, S. Liao, J. Kokontis, 1989 .

Structural Analysis and Gene Expression of TR2 Receptor and TR3 Receptor

Chawnshang Chang, J. Kokontis, T. Nakamoto, 1991 .

Cytochrome P450 genes are differentially expressed in female and male hepatocyte retinoid X receptor alpha-deficient mice.

Y. Ao, Chawnshang Chang, Yan Cai, 2003, Endocrinology.

TNF signaling mediates an enzalutamide-induced metastatic phenotype of prostate cancer and microenvironment cell co-cultures

S. Yeh, Chawnshang Chang, K. Nastiuk, 2015, Oncotarget.

Gender differences in liver diseases and their linkage to androgen / androgen receptor There are four major liver diseases associated with gender

S. Yeh, Chawnshang Chang, Wen-Lung Ma, 2014 .

Androgen receptor regulates ASS1P3/miR-34a-5p/ASS1 signaling to promote renal cell carcinoma cell growth

Chawnshang Chang, Yin Sun, Kefeng Wang, 2019, Cell Death & Disease.

The androgen receptor in bladder cancer

S. Yeh, Y. Tsai, Chawnshang Chang, 2023, Nature Reviews Urology.

Preclinical study using circular RNA 17 and micro RNA 181c-5p to suppress the enzalutamide-resistant prostate cancer progression

Chawnshang Chang, Y. Niu, Yin Sun, 2019, Cell Death & Disease.

The reduced trabecular bone mass of adult ARKO male mice results from the decreased osteogenic differentiation of bone marrow stroma cells.

Chawnshang Chang, C. Shyr, Ko-en Huang, 2011, Biochemical and biophysical research communications.

The miR-92a-2-5p in exosomes from macrophages increases liver cancer cells invasion via altering the AR/PHLPP/p-AKT/β-catenin signaling

S. Yeh, Chawnshang Chang, Yin Sun, 2020, Cell Death & Differentiation.

The miR-92a-2-5p in exosomes from macrophages increases liver cancer cells invasion via altering the AR/PHLPP/p-AKT/β-catenin signaling

S. Yeh, Chawnshang Chang, Yin Sun, 2020, Cell Death & Differentiation.

Targeting TR4 nuclear receptor suppresses prostate cancer invasion via reduction of infiltrating macrophages with alteration of the TIMP-1/MMP2/MMP9 signals

Chawnshang Chang, Dong-Rong Yang, Bi-de Chen, 2015, Molecular Cancer.

Induction oftheTRPM-2GeneinCells Undergoing Programmed Death

Chawnshang Chang, R. Buttyan, M. Bandyk, 1989 .

Correction to: Targeting TR4 nuclear receptor suppresses prostate cancer invasion via reduction of infiltrating acrophages with alteration of the TIMP-1/MMP2/MMP9 signals

Chawnshang Chang, Dong-Rong Yang, Bi-de Chen, 2020, Molecular Cancer.

Targeting TR4 nuclear receptor with antagonist bexarotene increases docetaxel sensitivity to better suppress the metastatic castration-resistant prostate cancer progression

Chawnshang Chang, Gonghui Li, Jie Luo, 2019, Oncogene.

TR4 nuclear receptor suppresses HCC cell invasion via downregulating the EphA2 expression

Chawnshang Chang, Gonghui Li, Xiujun Cai, 2018, Cell Death & Disease.

Recent advances in the study of testicular nuclear receptor 4

Chawnshang Chang, Bi-de Chen, Gong-hui Li, 2013, Journal of Zhejiang University SCIENCE B.

Induction of apolipoprotein E expression by TR4 orphan nuclear receptor via 5' proximal promoter region.

Chawnshang Chang, Eungseok Kim, Zhiming Yang, 2005, Biochemical and biophysical research communications.

Abstract 2126: Androgen receptor regulates lung cancer progress through modulation of OCT-4 expression

Cheng-Wen Wu, Chawnshang Chang, S. Yeh, 2011 .

The 56/58 kDa androgen-binding protein in male genital skin fibroblasts with a deleted androgen receptor gene

Carolyn J. Brown, H. Willard, D. Belsham, 1991, Molecular and Cellular Endocrinology.

Higher expression of peroxisome proliferator-activated receptor γ or its activation by agonist thiazolidinedione-rosiglitazone promotes bladder cancer cell migration and invasion.

E. Messing, Chawnshang Chang, H. Miyamoto, 2013, Urology.

Androgen dihydrotestosterone (DHT) promotes the bladder cancer nuclear AR-negative cell invasion via a newly identified membrane androgen receptor (mAR-SLC39A9)-mediated Gαi protein/MAPK/MMP9 intracellular signaling

E. Messing, S. Yeh, Chawnshang Chang, 2019, Oncogene.

ERβ-Mediated Alteration of circATP2B1 and miR-204-3p Signaling Promotes Invasion of Clear Cell Renal Cell Carcinoma.

S. Yeh, Chawnshang Chang, Jiaqi Chen, 2018, Cancer research.

TR4 Nuclear Receptor Different Roles in Prostate Cancer Progression

Chawnshang Chang, Dong-Rong Yang, Gonghui Li, 2015, Front. Endocrinol..

Preclinical studies using miR‐32‐5p to suppress clear cell renal cell carcinoma metastasis via altering the miR‐32‐5p/TR4/HGF/Met signaling

Chawnshang Chang, Dong-Rong Yang, Mingchao Wang, 2018, International journal of cancer.

Identification of a New Enhancer in the Promoter Region of Human TR3 Orphan Receptor Gene

Chawnshang Chang, A. Mizokami, Hiroji Uemura, 1995, The Journal of Biological Chemistry.

Transactivation of the proximal promoter of human oxytocin gene by TR4 orphan receptor.

Chawnshang Chang, Han-Jung Lee, Yi-Fen Lee, 2006, Biochemical and biophysical research communications.

Minireview: Pathophysiological roles of the TR4 nuclear receptor: lessons learned from mice lacking TR4.

Chawnshang Chang, Yanqing Zhang, Dong-Rong Yang, 2014, Molecular endocrinology.

Loss of testicular orphan receptor 4 impairs normal myelination in mouse forebrain.

Chawnshang Chang, Shaozhen Xie, Liang Wang, 2007, Molecular endocrinology.

Deficiency in Androgen Receptor Aggravates the Depressive-Like Behaviors in Chronic Mild Stress Model of Depression

Chawnshang Chang, Ya-Ling Huang, Hong-Yo Kang, 2019, Cells.

Premature aging with impaired oxidative stress defense in mice lacking TR4.

Chawnshang Chang, Gonghui Li, Wen-Jye Lin, 2011, American journal of physiology. Endocrinology and metabolism.

defense in mice lacking TR4 Premature aging with impaired oxidative stress

Chawnshang Chang, Qiao Wu, Gonghui Li, 2011 .

From HER 2 y Neu signal cascade to androgen receptor and its coactivators : A novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells

S. Yeh, Chawnshang Chang, Hui-Kuan Lin, 1999 .

Determination of androgen receptor degradation enhancer ASC-J9(®) in mouse sera and organs with liquid chromatography tandem mass spectrometry.

S. Yeh, Chawnshang Chang, Chiung-Kuei Huang, 2014, Journal of pharmaceutical and biomedical analysis.

Ontogeny and autoregulation of androgen receptor mRNA expression in the nervous system

Chawnshang Chang, W. Young, Win-Jing Young, 1998, Endocrine.

Androgen receptor increases hematogenous metastasis yet decreases lymphatic metastasis of renal cell carcinoma

Xin Ma, Xintao Li, Yu Gao, 2017, Nature Communications.

TR4 nuclear receptor increases prostate cancer invasion via decreasing the miR-373-3p expression to alter TGFβR2/p-Smad3 signals

Chawnshang Chang, Kun Fan, Dong-Rong Yang, 2015, Oncotarget.

Androgen receptor regulates expression of skeletal muscle-specific proteins and muscle cell types

Hong-Chiang Chang, S. Yeh, Chawnshang Chang, 2004, Endocrine.

The roles of testicular orphan nuclear receptor 4 (TR4) in cerebellar development

Chawnshang Chang, Yei-Tsung Chen, L. Collins, 2008, The Cerebellum.

Targeted activation of androgen receptor signaling in the periosteum improves bone fracture repair

Tien-Min G. Chu, Yun-Ju Chen, Chawnshang Chang, 2022, Cell Death & Disease.

Infiltrating T Cells Promote Bladder Cancer Progression via Increasing IL1→Androgen Receptor→HIF1α→VEGFa Signals

S. Yeh, Chawnshang Chang, Hong-gang Yu, 2016, Molecular Cancer Therapeutics.

An in Vitro Model for the Effects of Androgen on Neurons Employing Androgen Receptor-Transfected PC12 Cells

Robert H. Lustig, Chawnshang Chang, R. Lustig, 1994, Molecular and Cellular Neuroscience.

ARA67/PAT1 Functions as a Repressor To Suppress Androgen Receptor Transactivation

S. Yeh, Chawnshang Chang, Yanqing Zhang, 2004, Molecular and Cellular Biology.

Distribution of androgen and estrogen receptor mRNA‐containing cells in the rat brain: An in situ hybridization study

L. Swanson, Chawnshang Chang, M. Muramatsu, 1990, The Journal of comparative neurology.

Olaparib and enzalutamide synergistically suppress HCC progression via the AR‐mediated miR‐146a‐5p/BRCA1 signaling

Chawnshang Chang, Xiujun Cai, Hui Lin, 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Olaparib and Enzalutamide synergistically suppress HCC progression via the AR-mediated miR-146a-5p/BRCA1 signaling

Chawnshang Chang, Xiujun Cai, Hui Lin, 2019, bioRxiv.

The androgen receptor: a mediator of diverse responses.

Chawnshang Chang, E. Keller, C. Chang, 1996, Frontiers in bioscience : a journal and virtual library.

Isolation of Ku70-binding proteins (KUBs).

S. Yeh, D. Boothman, D. J. Chen, 1999, Nucleic acids research.

Differential androgen receptor signals in different cells explain why androgen-deprivation therapy of prostate cancer fails

Yuzhuo Wang, S. Yeh, Chawnshang Chang, 2010, Oncogene.

From HER2/Neu signal cascade to androgen receptor and its coactivators: a novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells.

S. Yeh, T. Thin, Chawnshang Chang, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Early Stage Biomarkers Screening of Prostate Cancer Based on Weighted Gene Coexpression Network Analysis.

Chawnshang Chang, Tao Shi, Lingyin Meng, 2019, DNA and cell biology.

Androgen receptor (AR) differential roles in hormone-related tumors including prostate, bladder, kidney, lung, breast and liver

S. Yeh, Chawnshang Chang, Soo Ok Lee, 2014, Oncogene.

Identification of 3',5'-cyclic adenosine monophosphate response element and other cis-acting elements in the human androgen receptor gene promoter.

S. Yeh, Chawnshang Chang, C. Chang, 1994, Molecular endocrinology.

Infiltrating bone marrow mesenchymal stem cells increase prostate cancer stem cell population and metastatic ability via secreting cytokines to suppress androgen receptor signaling

Chawnshang Chang, Jie Luo, L. Li, 2014, Oncogene.

Induction of the TRPM-2 gene in cells undergoing programmed death

C. Olsson, Chawnshang Chang, J. Pintar, 1989, Molecular and cellular biology.

Methylation of the androgen receptor promoter CpG island is associated with loss of androgen receptor expression in prostate cancer cells.

J. Herman, W. Isaacs, Y. Shi, 1998, Cancer research.

ASC-J9® increases the bladder cancer chemotherapy efficacy via altering the androgen receptor (AR) and NF-κB survival signals

E. Messing, S. Yeh, Chawnshang Chang, 2019, Journal of Experimental & Clinical Cancer Research.

An exonic point mutation of the androgen receptor gene in a family with complete androgen insensitivity.

S. Seino, Chawnshang Chang, J. Trapman, 1990, American journal of human genetics.

Molecular cloning of human and rat complementary DNA encoding androgen receptors.

Chawnshang Chang, S. Liao, J. Kokontis, 1988, Science.

Estrogen and G protein-coupled estrogen receptor accelerate the progression of benign prostatic hyperplasia by inducing prostatic fibrosis

S. Yeh, Chawnshang Chang, Ye Tian, 2022, Cell Death & Disease.

Polymorphic CAG and GGN repeat lengths in the androgen receptor gene and prostate cancer risk: a population-based case-control study in China.

J. Benichou, F. Mostofi, I. Sesterhenn, 2000, Cancer research.

Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells.

S. Yeh, Chawnshang Chang, C. Chang, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Identification of an essential cis-acting element (TR2-PACE) in the 5′ promoter of human TR2 orphan receptor gene

Chawnshang Chang, D. Lin, 2000, Endocrine.

Inhibition of NF (cid:107) B Activity through Maintenance of I (cid:107) B (cid:97) Levels Contributes to Dihydrotestosterone-mediated Repression of the Interleukin-6 Promoter*

Chawnshang Chang, E. Keller, W. Ershler, 1996 .

Increase of androgen-induced cell death and androgen receptor transactivation by BRCA1 in prostate cancer cells.

S. Yeh, Chawnshang Chang, Yueh-Chiang Hu, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of two cis-acting DNA elements involved in the androgen regulation of the probasin gene.

R. Matusik, N. Bruchovsky, P. Rennie, 1993, Molecular endocrinology.

389 EXPRESSION OF ANDROGEN AND ESTROGEN RECEPTORS AND ITS PROGNOSTIC SIGNIFICANCE IN UROTHELIAL NEOPLASM OF THE URINARY BLADDER

E. Messing, G. Netto, S. Yeh, 2012 .

Immunohistochemical localization of androgen receptors with mono- and polyclonal antibodies to androgen receptor.

Chawnshang Chang, C. Chang, G. Chodak, 1990, The Journal of endocrinology.

Retinoblastoma, a tumor suppressor, is a coactivator for the androgen receptor in human prostate cancer DU145 cells.

S. Yeh, Chawnshang Chang, J. Ludlow, 1998, Biochemical and biophysical research communications.

Early clinical characteristics and pregnancy outcomes of patients with influenza A (H1N1) infection requiring mechanical ventilation during pregnancy

Chawnshang Chang, W. Yao, Y. Cui, 2013, Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology.

Heterogeneity of androgen receptor content in advanced prostate cancer.

M. Loda, I. Kaplan, P. Hahnfeldt, 1997, Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc.

Stromal androgen receptor roles in the development of normal prostate, benign prostate hyperplasia, and prostate cancer.

Hong-Chiang Chang, Chawnshang Chang, Y. Niu, 2015, The American journal of pathology.

Promotion of bladder cancer development and progression by androgen receptor signals.

E. Messing, S. Yeh, Chawnshang Chang, 2007, Journal of the National Cancer Institute.

Decreased tumorigenesis and mortality from bladder cancer in mice lacking urothelial androgen receptor.

Xue-Ru Wu, Chawnshang Chang, H. Miyamoto, 2013, The American journal of pathology.

Defects of prostate development and reproductive system in the estrogen receptor-alpha null male mice.

E. Messing, S. Radovick, Ming Chen, 2009, Endocrinology.

Altered prostate epithelial development in mice lacking the androgen receptor in stromal fibroblasts

Hong-Chiang Chang, S. Yeh, H. Moses, 2012, The Prostate.

Preclinical Study Using ABT263 to Increase Enzalutamide Sensitivity to Suppress Prostate Cancer Progression Via Targeting BCL2/ROS/USP26 Axis Through Altering ARv7 Protein Degradation

Chawnshang Chang, D. Ye, Hua-Xiang Xu, 2020, Cancers.

Androgen receptor (AR) in cardiovascular diseases.

Chawnshang Chang, Chiung-Kuei Huang, Soo Ok Lee, 2016, The Journal of endocrinology.

Increased hepatic steatosis and insulin resistance in mice lacking hepatic androgen receptor

S. Yeh, Chawnshang Chang, S. Altuwaijri, 2008, Hepatology.

Infiltrating bone marrow mesenchymal stem cells increase prostate cancer stem cell population and metastatic ability via secreting cytokines to suppress androgen receptor signaling

Chawnshang Chang, Jie Luo, L. Li, 2014, Oncogene.

Epidermal growth factor enhances androgen receptor‑mediated bladder cancer progression and invasion via potentiation of AR transactivation.

Chawnshang Chang, Wei-Min Chuang, Wen-Lung Ma, 2013, Oncology reports.

The androgen receptor: a mediator of diverse responses.

Chawnshang Chang, W. Ershler, Evan Keller, 1996, Frontiers in bioscience : a journal and virtual library.

New Therapy via Targeting Androgen Receptor in Monocytes/Macrophages to Battle Atherosclerosis

Chawnshang Chang, Chiung-Kuei Huang, J. Sparks, 2014, Hypertension.

Differential Androgen Deprivation Therapies with AntiAndrogens of Casodex or MDV 3100 vs . AntiAndrogen Receptor of ASC-J 9 ® Lead to Promote vs . Suppress Prostate Cancer Metastasis

S. Yeh, Chawnshang Chang, S. Yeh, 2013 .

Androgen receptor is a new potential therapeutic target for the treatment of hepatocellular carcinoma.

S. Yeh, Chawnshang Chang, Y. Jou, 2008, Gastroenterology.

Androgen receptor influences on body defense system via modulation of innate and adaptive immune systems: lessons from conditional AR knockout mice.

Chawnshang Chang, S. Altuwaijri, Kuang-Hsiang Chuang, 2012, The American journal of pathology.

Androgen receptor promotes melanoma metastasis via altering the miRNA-539-3p/USP13/MITF/AXL signals

S. Yeh, Y. Wang, Chawnshang Chang, 2017, Oncogene.

Androgen receptor roles in hepatocellular carcinoma, fatty liver, cirrhosis and hepatitis.

S. Yeh, Chawnshang Chang, Wen-Lung Ma, 2014, Endocrine-related cancer.

9-cis-retinoic acid inhibits androgen receptor activity through activation of retinoid X receptor.

Chawnshang Chang, S. Altuwaijri, Chinyi Chu, 2005, Molecular endocrinology.

Gender difference in cytoprotection induced by estrogen on female and male bovine aortic endothelial cells

Chawnshang Chang, R. Khardori, C. Su, 2001, Endocrine.

Modulation of androgen receptor transactivation by gelsolin: a newly identified androgen receptor coregulator.

Hong-Chiang Chang, S. Yeh, K. Aozasa, 2003, Cancer research.

YAP1 regulates prostate cancer stem cell-like characteristics to promote castration resistant growth

Chawnshang Chang, Qiang Wang, Tao Wu, 2017, Oncotarget.

Androgen receptor (AR) promotes clear cell renal cell carcinoma (ccRCC) migration and invasion via altering the circHIAT1/miR-195-5p/29a-3p/29c-3p/CDC42 signals.

Chawnshang Chang, W. Tao, Yin Sun, 2017, Cancer letters.

Correction to: Androgen receptor regulates expression of skeletal muscle–specific proteins and muscle cell types

Hong-Chiang Chang, S. Yeh, Chawnshang Chang, 2020, Endocrine.

Topographic recognition of cyclic hydrocarbons and related compounds by receptors for androgens, estrogens, and glucocorticoids.

Chawnshang Chang, C. Chang, S. Liao, 1987, Journal of steroid biochemistry.

Replacement of arginine 773 by cysteine or histidine in the human androgen receptor causes complete androgen insensitivity with different receptor phenotypes.

D. Belsham, Chawnshang Chang, J. Trapman, 1992, American journal of human genetics.