A. Greenleaf

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Phosphorylation and functions of the RNA polymerase II CTD.

H. Phatnani, A. Greenleaf, Hemali P Phatnani, 2006, Genes & development.

Drosophila RNA Polymerase II Mutants That Affect Transcription Elongation (*)

A. Greenleaf, D. Price, Y. Chen, 1996, The Journal of Biological Chemistry.

The Splicing Factor, Prp40, Binds the Phosphorylated Carboxyl-terminal Domain of RNA Polymerase II*

A. Greenleaf, A L Greenleaf, D. P. Morris, 2000, The Journal of Biological Chemistry.

Protein-interaction modules that organize nuclear function: FF domains of CA150 bind the phosphoCTD of RNA polymerase II.

M. Garcia-Blanco, A. Greenleaf, A C Goldstrohm, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Phosphorylation of RNA polymerase II CTD fragments results in tight binding to the WW domain from the yeast prolyl isomerase Ess1.

T. Oas, A. Greenleaf, J. Myers, 2001, Biochemistry.

Locus-specific variation in phosphorylation state of RNA polymerase II in vivo: correlations with gene activity and transcript processing.

J. M. Lee, A. Greenleaf, J. Weeks, 1993, Genes & development.

α-amanitin-resistant D. melanogaster with an altered RNA polymerase II

A. Greenleaf, L. M. Borsett, P. F. Jiamachello, 1979, Cell.

Modulation of RNA Polymerase II Elongation Efficiency by C-terminal Heptapeptide Repeat Domain Kinase I*

A. Greenleaf, J. Lee, 1997, The Journal of Biological Chemistry.

Solution structure of the Set2-Rpb1 interacting domain of human Set2 and its interaction with the hyperphosphorylated C-terminal domain of Rpb1.

H. Phatnani, A. Greenleaf, Z. Guan, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Expanding the functional repertoire of CTD kinase I and RNA polymerase II: novel phosphoCTD-associating proteins in the yeast proteome.

H. Phatnani, A. Greenleaf, Janice C. Jones, 2004, Biochemistry.

Dynamic interaction between a Drosophila transcription factor and RNA polymerase II

A. Sluder, A. Greenleaf, D. Price, 1989, Molecular and cellular biology.

RNA Polymerase B from Drosophila melanogaster Larvae

A. Greenleaf, E. Bautz, 1975 .

Covalent targeting of remote cysteine residues to develop CDK12 and CDK13 inhibitors.

N. Hannett, R. Young, N. Gray, 2016, Nature chemical biology.

Localization of RNA polymerase in polytene chromosomes of Drosophila melanogaster.

A. Greenleaf, M. Jamrich, E. Bautz, 1977, Proceedings of the National Academy of Sciences of the United States of America.

Isolation of a new RNA polymerase-binding protein from sporulating Bacillus subtilis.

R. Losick, A. Greenleaf, T. Linn, 1973, Proceedings of the National Academy of Sciences of the United States of America.

Functional studies of the carboxy-terminal repeat domain of Drosophila RNA polymerase II in vivo.

A. Greenleaf, W. J. Brickey, W. Brickey, 1995, Genetics.

Immunological studies of RNA polymerase II using antibodies to subunits of Drosophila and wheat germ enzyme.

A. Greenleaf, J. Weeks, D. E. Coulter, 1982, The Journal of biological chemistry.

Heat-shock-specific phosphorylation and transcriptional activity of RNA polymerase II.

E. Egyházi, J. M. Lee, T. Mäkelä, 1998, Experimental cell research.

Elongation by Drosophila RNA polymerase II. Transcription of 3'-extended DNA templates.

A. Sluder, A. Greenleaf, D. Price, 1988, The Journal of biological chemistry.

Phosphorylation of RNA polymerase II C-terminal domain and transcriptional elongation

J. Lis, T. O'Brien, A. Greenleaf, 1994, Nature.

Phosphorylation dependence of the initiation of productive transcription of balbiani ring 2 genes in living cells

E. Egyházi, A. Greenleaf, A. Ossoinak, 1996, Chromosoma.

A mutation in the largest subunit of RNA polymerase II alters RNA chain elongation in vitro.

A. Greenleaf, D. E. Coulter, 1985, The Journal of biological chemistry.

Fractionation of transcription factors for RNA polymerase II from Drosophila Kc cell nuclear extracts.

A. Sluder, A. Greenleaf, D. Price, 1987, The Journal of biological chemistry.

Properties of a Drosophila RNA polymerase II elongation factor.

A. Sluder, A. Greenleaf, D. Price, 1989, The Journal of biological chemistry.

Mapping mutations in genes encoding the two large subunits of Drosophila RNA polymerase II defines domains essential for basic transcription functions and for proper expression of developmental genes

A. Greenleaf, Y. Chen, M. Mortin, 1993, Molecular and cellular biology.

Identification, molecular cloning, and mutagenesis of Saccharomyces cerevisiae RNA polymerase genes.

M. Shales, C. Ingles, A. Greenleaf, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Properties of mutationally altered RNA polymerases II of Drosophila.

A. Greenleaf, D. E. Coulter, 1982, The Journal of biological chemistry.

Reverse genetics of Drosophila RNA polymerase II: identification and characterization of RpII140, the genomic locus for the second-largest subunit.

A. Greenleaf, M. Mortin, B. Hamilton, 1993, Genetics.

CDK12 regulates co-transcriptional splicing and RNA turnover in human cells

M. Ljungman, A. Greenleaf, M. Paulsen, 2022, iScience.

melanogaster RpII215. Drosophila element deletions in the 5' region of Sites of P element insertion and structures of P

A. Greenleaf, L. L. Searles, W. E. Kemp, 2013 .

Isolation of the nuclear gene encoding a subunit of the yeast mitochondrial RNA polymerase.

I. Lehman, A. Greenleaf, J. Kelly, 1986, The Journal of biological chemistry.

Frequent Imprecise Excision among Reversions of a P Element-Caused Lethal Mutation in Drosophila.

G. B. Wisely, A. Greenleaf, H. Gyurkovics, 1984, Genetics.

The essential sequence elements required for RNAP II carboxyl-terminal domain function in yeast and their evolutionary conservation.

A. Greenleaf, Pengda Liu, Pengda Liu, 2008, Molecular biology and evolution.

Phosphorylation of RNAPII

A. Greenleaf, Bartlomiej Bartkowiak, 2011, Transcription.

The Splicing Factor , Prp 40 , Binds the Phosphorylated Carboxyl-terminal Domain of RNA Polymerase II *

A. Greenleaf, D. P. Morris, 2000 .

On the specificity of creatine kinase. New glycocyamines and glycocyamine analogs related to creatine.

G. L. Kenyon, A. Greenleaf, Gerald L. Rowley, 1971, Journal of the American Chemical Society.

Juglone, an inhibitor of the peptidyl-prolyl isomerase Pin1, also directly blocks transcription.

A. Greenleaf, D. Price, S. Chao, 2001, Nucleic acids research.

Analysis of the gene encoding the largest subunit of RNA polymerase II in Drosophila

A. Greenleaf, J. Weeks, R. Jokerst, 2004, Molecular and General Genetics MGG.

Specific Interaction of the Transcription Elongation Regulator TCERG1 with RNA Polymerase II Requires Simultaneous Phosphorylation at Ser2, Ser5, and Ser7 within the Carboxyl-terminal Domain Repeat*

A. Greenleaf, S. Fan, Chul-Jin Lee, 2013, The Journal of Biological Chemistry.

Ser 2 Phosphorylation at Ser Polymerase II Requires Simultaneous Elongation Regulator TCERG 1 with RNA Specific Interaction of the Transcription Gene Regulation :

A. Greenleaf, S. Fan, Chul-Jin Lee, 2013 .

Proteomic Analysis of Mitotic RNA Polymerase II Reveals Novel Interactors and Association With Proteins Dysfunctional in Disease*

S. Q. Xie, Ana Pombo, M Madan Babu, 2011, Molecular & Cellular Proteomics.

Functional organization of polytene chromosomes.

A. Greenleaf, M. Jamrich, E. Bautz, 1978, Cold Spring Harbor symposia on quantitative biology.

α-Amanitin Tolerance in Mycophagous Drosophila

D. Grimaldi, A. Sluder, A. Greenleaf, 1983, Science.

agr-Amanitin Tolerance in Mycophagous Drosophila.

D. Grimaldi, A. Sluder, A. Greenleaf, 1983, Science.

C-terminal Repeat Domain Kinase I Phosphorylates Ser2 and Ser5 of RNA Polymerase II C-terminal Domain Repeats*

S. Munir Alam, Hemali P. Phatnani, T. Haystead, 2004, Journal of Biological Chemistry.

Genetic and biochemical characterization of mutants at an RNA polymerase II locus in D. melanogaster

A. Greenleaf, J. Weeks, R. A. Voelker, 1980, Cell.

In vitro proteolysis of a large subunit of Drosophila melanogaster RNA polymerase B

A. Greenleaf, R. Haars, E. Bautz, 1976, FEBS letters.

CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylation

Daniel S. Day, R. Young, Guocheng Yuan, 2018, Nature Communications.

A Novel Domain in Set2 Mediates RNA Polymerase II Interaction and Couples Histone H3 K36 Methylation with Transcript Elongation

Brian D. Strahl, Hana Hall, Hemali P. Phatnani, 2005, Molecular and Cellular Biology.

CDK12 Activity-Dependent Phosphorylation Events in Human Cells

A. Greenleaf, E. Soderblom, Chris Yan, 2019, Biomolecules.

CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1.

J. Lis, K. Adelman, H. Phatnani, 2010, Genes & development.

Human CDK12 and CDK13, multi-tasking CTD kinases for the new millenium

A. Greenleaf, 2018, Transcription.

Yeast RPO41 gene product is required for transcription and maintenance of the mitochondrial genome.

I. Lehman, A. Greenleaf, J. Kelly, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Positive patches and negative noodles: linking RNA processing to transcription?

A. Greenleaf, Arno L. Greenleaf, 1993, Trends in biochemical sciences.

RNA polymerase from sporulating Bacillus subtilis. Purification and properties of a modified form of the enzyme containing two sporulation polypeptides.

R. Losick, A. Greenleaf, T. Linn, 1975, The Journal of biological chemistry.

Co-transcriptional splicing of pre-messenger RNAs: considerations for the mechanism of alternative splicing.

M. Garcia-Blanco, A. Greenleaf, A C Goldstrohm, 2001, Gene.

Loss of the sigma activity of RNA polymerase of Bacillus subtilis during sporulation.

R. Losick, A. Greenleaf, T. Linn, 1973, Proceedings of the National Academy of Sciences of the United States of America.

The yeast carboxyl-terminal repeat domain kinase CTDK-I is a divergent cyclin-cyclin-dependent kinase complex

D. Sterner, J. M. Lee, A. Greenleaf, 1995, Molecular and cellular biology.

Analyses of promoter-proximal pausing by RNA polymerase II on the hsp70 heat shock gene promoter in a Drosophila nuclear extract

D. Gilmour, A. Greenleaf, Y. Chen, 1996, Molecular and cellular biology.

RNA Polymerase B (or II) in heat induced puffs of Drosophila polytene chromosomes

A. Greenleaf, M. Jamrich, E. Bautz, 1978, Chromosoma.

The RNA polymerase II CTD kinase CTDK-I affects pre-mRNA 3' cleavage/polyadenylation through the processing component Pti1p.

A. Greenleaf, D. Skaar, David A Skaar, 2002, Molecular cell.

Comparative Genome-Wide Screening Identifies a Conserved Doxorubicin Repair Network That Is Diploid Specific in Saccharomyces cerevisiae

J. Olson, K. Blackwell, A. Greenleaf, 2009, PloS one.

Kin28, the TFIIH-Associated Carboxy-Terminal Domain Kinase, Facilitates the Recruitment of mRNA Processing Machinery to RNA Polymerase II

C. Moore, M. Keogh, E. Cho, 2000, Molecular and Cellular Biology.

Updating the CTD Story: From Tail to Epic

A. Greenleaf, April L MacKellar, Bartlomiej Bartkowiak, 2011, Genetics research international.

Engineering an analog-sensitive CDK12 cell line using CRISPR/Cas.

A. Greenleaf, Bartlomiej Bartkowiak, Christopher M Yan, 2015, Biochimica et biophysica acta.

Cotranscriptional Association of mRNA Export Factor Yra1 with C-terminal Domain of RNA Polymerase II*

A. Greenleaf, Arno L Greenleaf, April L MacKellar, 2011, The Journal of Biological Chemistry.

cis-Proline-mediated Ser(P)5 Dephosphorylation by the RNA Polymerase II C-terminal Domain Phosphatase Ssu72*

N. Nicely, A. Greenleaf, Pengda Liu, 2010, The Journal of Biological Chemistry.

Genetic organization, length conservation, and evolution of RNA polymerase II carboxyl-terminal domain.

A. Greenleaf, Pengda Liu, J. Kenney, 2010, Molecular biology and evolution.

Yeast Screens Identify the RNA Polymerase II CTD and SPT5 as Relevant Targets of BRCA1 Interaction

D. D. Bailey, C. Blanchette, J. Olson, 2008, PloS one.

Detecting PCAPs by Far Western Blotting

H. Phatnani, A. Greenleaf, 2018 .

Identifying phosphoCTD-associating proteins.

H. Phatnani, A. Greenleaf, 2004, Methods in molecular biology.

Hyperphosphorylated C-terminal Repeat Domain-associating Proteins in the Nuclear Proteome Link Transcription to DNA/Chromatin Modification and RNA Processing*

A. Greenleaf, S. M. Carty, 2002, Molecular & Cellular Proteomics.

Appearance of a Ribonucleic Acid Polymerase-Binding Protein in Asporogenous Mutants of Bacillus subtilis

R. Losick, A. Greenleaf, 1973, Journal of bacteriology.

Heat shock-induced appearance of RNA polymerase II in karyoskeletal protein-enriched (nuclear "matrix") fractions correlates with transcriptional shutdown in Drosophila melanogaster.

J. M. Lee, A. Greenleaf, L. Lin, 1989, The Journal of biological chemistry.

Protonation of the neutral repeats of the RNA polymerase II CTD.

A. Greenleaf, D. P. Morris, R. Stevens, 1998, Biochemical and biophysical research communications.

Assaying CTD kinases in vitro and phosphorylation-modulated properties of RNA polymerase II in vivo.

D. Sterner, J. M. Lee, A. Greenleaf, 1997, Methods.

The C-terminal repeat domain of RNA polymerase II largest subunit is essential in vivo but is not required for accurate transcription initiation in vitro.

J. M. Lee, A. Greenleaf, J. Weeks, 1988, Proceedings of the National Academy of Sciences of the United States of America.

A DNA Damage Response System Associated with the phosphoCTD of Elongating RNA Polymerase II

A. Greenleaf, C. Bennett, Bartlomiej Bartkowiak, 2013, PloS one.

RECQ5 helicase associates with the C-terminal repeat domain of RNA polymerase II during productive elongation phase of transcription

A. Greenleaf, M. Menigatti, I. Shevelev, 2010, Nucleic acids research.

The phosphoCTD-interacting domain of Topoisomerase I.

H. Phatnani, A. Greenleaf, Jianhong Wu, 2010, Biochemical and biophysical research communications.

Getting a grip on the CTD of Pol II.

A. Greenleaf, 2003, Structure.

CTD kinase large subunit is encoded by CTK1, a gene required for normal growth of Saccharomyces cerevisiae.

J. M. Lee, A. Greenleaf, 1991, Gene expression.

A protein kinase that phosphorylates the C-terminal repeat domain of the largest subunit of RNA polymerase II.

J. M. Lee, A. Greenleaf, J. Lee, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Amanitin-resistant RNA polymerase II mutations are in the enzyme's largest subunit.

A. Greenleaf, 1983, The Journal of biological chemistry.

Expression, Purification, and Identification of Associated Proteins of the Full-length hCDK12/CyclinK Complex

A. Greenleaf, Bartlomiej Bartkowiak, 2014, The Journal of Biological Chemistry.

Expression, Purification, and Identification of Associated Proteins of the Full-length hCDK12/CyclinK Complex*

A. Greenleaf, Bartlomiej Bartkowiak, 2014, The Journal of Biological Chemistry.

An activity necessary for in vitro transcription is a DNase inhibitor.

A. Sluder, A. Greenleaf, D. Price, 1987, Biochimie.

Sites of P element insertion and structures of P element deletions in the 5' region of Drosophila melanogaster RpII215

A. Greenleaf, L. L. Searles, W. E. Kemp, 1986, Molecular and cellular biology.

Affinity-purified antibody as a probe of RNA polymerase II subunit structure.

R. Tjian, A. Greenleaf, W. Dynan, 1984, Journal of molecular and applied genetics.

Molecular cloning of sequences from a drosophila RNA polymerase II locus by P element transposon tagging

P. Bingham, A. Greenleaf, L. L. Searles, 1982, Cell.

RNA polymerase B from Drosophila melanogaster larvae. Purification and partial characterization.

A. Greenleaf, E. Bautz, 1975, European journal of biochemistry.

Distribution of RNA polymerase on Drosophila polytene chromosomes as studied by indirect immunofluorescence

A. Greenleaf, E. Bautz, U. Plagens, 1976, Chromosoma.

DNA-dependent RNA Polymerases from Drosophila melanogaster Larvae

A. Krämer, A. Greenleaf, E. Bautz, 1976 .

Pro - and Eukaryotic RNA Polymerases

A. Greenleaf, R. Haars, G. Gross, 1977 .

LOCALIZATION OF RNA POLYMERASE ON DROSOPHILA POLYTENE CHROMOSOMES BY INDIRECT IMMUNOFLUORESCENCE

A. Greenleaf, E. Bautz, U. Plagens, 1976 .

Identification of a structural gene for a RNA polymerase II polypeptide in Drosophila melanogaster and mammalian species.

C. Ingles, J. Biggs, A. Greenleaf, 1983, Proceedings of the National Academy of Sciences of the United States of America.

The carboxyl-terminal repeat domain of RNA polymerase II is not required for transcription factor Sp1 to function in vitro.

A. Greenleaf, W. Zehring, 1990, The Journal of biological chemistry.

CDK12 loss in cancer cells affects DNA damage response genes through premature cleavage and polyadenylation

Daniel S. Day, R. Young, N. Gray, 2018, bioRxiv.

Identifying a transcription factor interaction site on RNA polymerase II.

A. Greenleaf, A. Skantar, 1995, Gene Expression.

Phospho-Carboxyl-Terminal Domain Binding and the Role of a Prolyl Isomerase in Pre-mRNA 3′-End Formation*

H. Phatnani, A. Greenleaf, A L Greenleaf, 1999, The Journal of Biological Chemistry.

3 RNA Polymerase II Subunits, Transcription Factors, and Kinases: Investigations in Drosophila melanogaster and Saccharomyces cerevisiae

A. Greenleaf, 1992 .

Structure of the eukaryotic transcription apparatus: Features of the gene for the largest subunit of Drosophila RNA polymerase II

J. Biggs, A. Greenleaf, L. L. Searles, 1985, Cell.

A positive addition to a negative tail's tale.

A. Greenleaf, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Alpha-amanitin-resistant D. melanogaster with an altered RNA polymerase II.

A. Greenleaf, L. M. Borsett, P. F. Jiamachello, 1979, Cell.

Covalent targeting of remote cysteine residues to develop CDK12 and 13 inhibitors

Richard A. Young, N. Hannett, N. Gray, 2016 .

FREQUENT IMPRECISE EXCISION AMONG REVERSIONS DROSOPHILA OF A P ELEMENT-CAUSED LETHAL MUTATION IN

A. Greenleaf, H. Gyurkovics, L. L. Searles, 2003 .

Proteomic Analysis of Mitotic RNA Polymerase II Reveals Novel Interactors and Association With Proteins Dysfunctional in Disease*

S. Q. Xie, M. Babu, M. Selbach, 2011, Molecular & Cellular Proteomics.