M. Blough

发表

Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers

Wei Wu, Steven J. M. Jones, Shaun D. Jackman, 2012, The Journal of pathology.

Lactate dehydrogenase A silencing in IDH mutant gliomas.

S. Weiss, J. Cairncross, M. Blough, 2014, Neuro-oncology.

Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression

Steven J. M. Jones, Karlyne M. Reilly, M. Marra, 2020, Nature Communications.

O 6-Methylguanine-DNA Methyltransferase Regulation by p 53 in Astrocytic Cells

J. Cairncross, M. Blough, M. Zlatescu, 2007 .

O6-methylguanine-DNA methyltransferase regulation by p53 in astrocytic cells.

J. Cairncross, M. Blough, M. Zlatescu, 2007, Cancer research.

In the beginning: PDGFA and the genesis of GBM.

J. Cairncross, M. Blough, P. Bose, 2021, Neuro-oncology.

On-target JAK 2 / STAT 3 inhibition slows disease progression in orthotopic xenografts of human glioblastoma brain tumor stem cells

S. Weiss, J. Cairncross, M. Blough, 2013 .

Effect of aberrant p53 function on temozolomide sensitivity of glioma cell lines and brain tumor initiating cells from glioblastoma

J. Cairncross, M. Blough, J. Kelly, 2011, Journal of Neuro-Oncology.

Mutations in CIC and IDH1 cooperatively regulate 2-hydroxyglutarate levels and cell clonogenicity

M. Marra, J. Cairncross, G. Morin, 2014, Oncotarget.

Single-cell landscapes of primary glioblastomas and matched explants and cell lines show variable retention of inter- and intratumor heterogeneity.

M. Marra, J. Cairncross, D. Trinh, 2022, Cancer cell.

Comparative genomic and genetic analysis of glioblastoma-derived brain tumor-initiating cells and their parent tumors.

M. Blough, B. Davis, H. A. Luchman, 2016, Neuro-oncology.

Sensitivity to temozolomide in brain tumor initiating cells.

S. Weiss, J. Cairncross, M. Blough, 2010, Neuro-oncology.

Small molecule epigenetic screen identifies novel EZH2 and HDAC inhibitors that target glioblastoma brain tumor-initiating cells

Steven J. M. Jones, M. Marra, Jake Lever, 2016, Oncotarget.

On-target JAK2/STAT3 inhibition slows disease progression in orthotopic xenografts of human glioblastoma brain tumor stem cells.

S. Weiss, J. Cairncross, M. Blough, 2013, Neuro-oncology.

Oligodendroglioma cell lines containing t(1;19)(q10;p10).

S. Weiss, J. Cairncross, D. Demetrick, 2010, Neuro-oncology.

Single-cell landscapes of primary glioblastomas and matched organoids and cell lines reveal variable retention of inter- and intra-tumor heterogeneity

M. Marra, J. Cairncross, M. Blough, 2021, bioRxiv.

Hyperpolarized 13C MR imaging detects no lactate production in mutant IDH1 gliomas: Implications for diagnosis and response monitoring

J. Cairncross, C. Najac, M. Blough, 2016, NeuroImage: Clinical.

An in vivo patient-derived model of endogenous IDH1-mutant glioma.

S. Weiss, J. Cairncross, A. Weljie, 2012, Neuro-oncology.

Comprehensive genomic profiling of glioblastoma tumors, BTICs, and xenografts reveals stability and adaptation to growth environments

Steven J. M. Jones, Richard A. Moore, S. Weiss, 2019, Proceedings of the National Academy of Sciences.

ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenografts

M. Marra, W. Mason, J. Cairncross, 2018, PloS one.

Capicua regulates neural stem cell proliferation and lineage specification through control of Ets factors

R. Dixit, C. Schuurmans, M. Marra, 2019, Nature Communications.

PARP inhibition suppresses the emergence of temozolomide resistance in a model system

J. Cairncross, M. Blough, L. Maxwell, 2020, Journal of Neuro-Oncology.

A novel C19MC amplified cell line links Lin28/let-7 to mTOR signaling in embryonal tumor with multilayered rosettes.

J. Cairncross, C. Hawkins, M. Blough, 2014, Neuro-oncology.

PDGF gene expression and p53 alterations contribute to the biology of diffuse astrocytic gliomas

M. Blough, P. Bose, G. Cairncross, 2023, npj Genomic Medicine.

Molecular Determinants of Prognosis and Evolution in Diffuse-Lower Grade Astrocytomas

J. Cairncross, M. Blough, P. Bose, 2020, bioRxiv.

In Vitro Modeling of GBM Initiation using PDGF-AA and P53-Null Neural Progenitors.

S. Weiss, J. Cairncross, E. Holland, 2020, Neuro-oncology.

Beyond Conventional Models: Recreating the Initiation, Evolution, and Genome of GBM

S. Weiss, J. Cairncross, E. Holland, 2019, bioRxiv.

Regulation of cell fate in neurodevelopment and oligodendroglioma by the transcriptional repressor Capicua

R. Dixit, C. Schuurmans, M. Blough, 2018 .

Capicua regulates neural stem cell proliferation and lineage specification through control of Ets factors

R. Dixit, C. Schuurmans, M. Marra, 2018, bioRxiv.

Capicua regulates neural stem cell proliferation and lineage specification through control of Ets factors

R. Dixit, C. Schuurmans, J. Cairncross, 2018, bioRxiv.

IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism.

S. Weiss, J. Cairncross, J. L. Izquierdo-García, 2015, Cancer research.

DNA hypermethylation and 1p Loss silence NHE‐1 in oligodendroglioma

S. Weiss, M. Marra, J. Cairncross, 2012, Annals of neurology.

p53 binding to the p21 promoter is dependent on the nature of DNA damage

R. Hill, M. Blough, Patrick Lee, 2008, Cell cycle.

A Phase I trial to inform clinical protocols for the safe administration of psilocybin-assisted psychotherapy

M. Blough, Lyle Galloway, J. Bennett, 2023, medRxiv.

2011 Jeremy Jass Prize for Research Excellence in Pathology

Jenny Q. Qian, I. Birol, S. Weiss, 2012 .

On-target JAK2/STAT3 inhibition slows disease progression in orthotopic xenografts of human glioblastoma brain tumor stem cells.

S. Weiss, J. Cairncross, M. Blough, 2013, Neuro-oncology.