Daniel Lai

发表

The clonal and mutational evolution spectrum of primary triple-negative breast cancers

Irmtraud M. Meyer, A. Bashashati, I. Birol, 2012, Nature.

Integrative analysis of genome-wide loss of heterozygosity and monoallelic expression at nucleotide resolution reveals disrupted pathways in triple-negative breast cancer

A. Bashashati, M. Marra, M. Hirst, 2012, Genome research.

Resource: Scalable whole genome sequencing of 40,000 single cells identifies stochastic aneuploidies, genome replication states and clonal repertoires

Richard A. Moore, C. Steidl, M. Marra, 2018, bioRxiv.

Dissociation of solid tumor tissues with cold active protease for single-cell RNA-seq minimizes conserved collagenase-associated stress responses

Kieran R. Campbell, Richard A. Moore, Allen W. Zhang, 2019, Genome Biology.

Dissociation of solid tumour tissues with cold active protease for single-cell RNA-seq minimizes conserved collagenase-associated stress responses

Kieran R. Campbell, Richard A. Moore, Allen W. Zhang, 2019, bioRxiv.

Clonal Decomposition and DNA Replication States Defined by Scaled Single-Cell Genome Sequencing

Richard A. Moore, Khanh N. Dinh, S. Tavaré, 2019, Cell.

On the importance of cotranscriptional RNA structure formation

Irmtraud M. Meyer, I. Meyer, Daniel Lai, 2013, RNA.

R-chie: a web server and R package for visualizing RNA secondary structures

Daniel Lai, Irmtraud M. Meyer, I. Meyer, 2012, Nucleic acids research.

Single cell transcriptomes of normal endometrial derived organoids uncover novel cell type markers and cryptic differentiation of primary tumours

Kieran R. Campbell, S. Leung, S. Shah, 2020, The Journal of pathology.

A comprehensive comparison of general RNA–RNA interaction prediction methods

Daniel Lai, Irmtraud M. Meyer, Irmtraud M Meyer, 2015, Nucleic acids research.

clonealign: statistical integration of independent single-cell RNA & DNA-seq from human cancers

Kieran R. Campbell, A. Bouchard-Côté, S. Shah, 2018, bioRxiv.

Interfaces of Malignant and Immunologic Clonal Dynamics in Ovarian Cancer

Wyeth W. Wasserman, Sohrab P. Shah, Ali Bashashati, 2018, Cell.

clonealign: statistical integration of independent single-cell RNA and DNA sequencing data from human cancers

Kieran R. Campbell, A. Bouchard-Côté, S. Shah, 2019, Genome Biology.

Epiclomal: Probabilistic clustering of sparse single-cell DNA methylation data

Richard A. Moore, Mirela Andronescu, M. Hirst, 2018, bioRxiv.

Chemogenomic profiling of breast cancer patient-derived xenografts reveals targetable vulnerabilities for difficult-to-treat tumors

S. Shah, S. Aparicio, A. Wan, 2020, Communications Biology.

Genomic consequences of aberrant DNA repair mechanisms stratify ovarian cancer histotypes

Ali Bashashati, Richard A. Moore, Gavin Ha, 2017, Nature Genetics.

Accurate determination of CRISPR-mediated gene fitness in transplantable tumours

Mirela Andronescu, A. Bouchard-Côté, S. McKinney, 2022, Nature Communications.

Genome-wide discovery of somatic regulatory variants in diffuse large B-cell lymphoma

Steven J. M. Jones, Christian Steidl, Dipankar Sen, 2018, Nature Communications.

Single-cell genomic variation induced by mutational processes in cancer

Allen W. Zhang, Nicole Rusk, A. McPherson, 2022, Nature.

Cancer phylogenetic tree inference at scale from 1000s of single cell genomes

Kieran R. Campbell, Marc J. Williams, Mirela Andronescu, 2020, bioRxiv.

Robust high-performance nanoliter-volume single-cell multiple displacement amplification on planar substrates

Ali Bashashati, Martin Hirst, Kaston Leung, 2016, Proceedings of the National Academy of Sciences.

Results of the phase I CCTG IND.231 trial of CX-5461 in patients with advanced solid tumors enriched for DNA-repair deficiencies

Bingshu E. Chen, A. Tinker, H. Feilotter, 2022, Nature Communications.

CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours

Jian Xian, Anni Zhang, Carlos Caldas, 2017, Nature Communications.

Dissociation of solid tumor tissues with cold active protease for single-cell RNA-seq minimizes conserved collagenase-associated stress responses

Kieran R. Campbell, Allen W. Zhang, S. Shah, 2019, Genome Biology.

Probabilistic cell-type assignment of single-cell RNA-seq for tumor microenvironment profiling

Kieran R. Campbell, Christian Steidl, Daniel Lai, 2019, Nature Methods.

Probabilistic cell type assignment of single-cell transcriptomic data reveals spatiotemporal microenvironment dynamics in human cancers

Kieran R. Campbell, Andrew P. Weng, Timothy A. Chan, 2019, bioRxiv.

Clonal fitness inferred from time-series modelling of single-cell cancer genomes

Kieran R. Campbell, Marc J. Williams, Richard A. Moore, 2021, Nature.

clonealign: statistical integration of independent single-cell RNA and DNA sequencing data from human cancers

Kieran R. Campbell, A. Bouchard-Côté, S. Shah, 2019, Genome Biology.

Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 as Therapeutic Target for Enhancing Immune Recognition.

Ryan D. Morin, R. Gascoyne, D. Scott, 2019, Cancer discovery.