Chyi-Ying A. Chen

发表

RNA stabilization by the AU‐rich element binding protein, HuR, an ELAV protein

A. Shyu, S. Peng, Chyi-Ying A. Chen, 1998, The EMBO journal.

The p38 MAP kinase pathway signals for cytokine‐induced mRNA stabilization via MAP kinase‐activated protein kinase 2 and an AU‐rich region‐targeted mechanism

Klaus Resch, Michael Kracht, M. Gaestel, 1999, The EMBO journal.

An intercistronic stem-loop structure functions as an mRNA decay terminator necessary but insufficient for puf mRNA stability

Stanley N Cohen, J. Belasco, Chyi-Ying A. Chen, 1988, Cell.

Human TOB, an Antiproliferative Transcription Factor, Is a Poly(A)-Binding Protein-Dependent Positive Regulator of Cytoplasmic mRNA Deadenylation

Tsung-Cheng Chang, A. Shyu, Chyi-Ying A. Chen, 2007, Molecular and Cellular Biology.

Antagonistic actions of two human Pan3 isoforms on global mRNA turnover

Jeffrey T. Chang, A. Shyu, Chyi-Ying A. Chen, 2017, RNA.

Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells

A. Shyu, Chyi-Ying A. Chen, Xiangwei He, 2008, The Journal of cell biology.

Functional dissection of hnRNP D suggests that nuclear import is required before hnRNP D can modulate mRNA turnover in the cytoplasm.

A. Shyu, Chyi-Ying A. Chen, N. Xu, 2004, RNA.

UNR, a new partner of poly(A)-binding protein, plays a key role in translationally coupled mRNA turnover mediated by the c-fos major coding-region determinant.

Tsung-Cheng Chang, N. Sonenberg, A. Shyu, 2004, Genes & development.

Rapid Deadenylation Triggered by a Nonsense Codon Precedes Decay of the RNA Body in a Mammalian Cytoplasmic Nonsense-Mediated Decay Pathway

A. Shyu, Chyi-Ying A. Chen, 2003, Molecular and Cellular Biology.

Nonsense-Mediated Decay Pathway RNA Body in a Mammalian Cytoplasmic Nonsense Codon Precedes Decay of the Rapid Deadenylation Triggered by a

A. Shyu, Chyi-Ying A. Chen, 2003 .

Versatile Role for hnRNP D Isoforms in the Differential Regulation of Cytoplasmic mRNA Turnover

A. Shyu, Chyi-Ying A. Chen, N. Xu, 2001, Molecular and Cellular Biology.

A Mechanism for Translationally Coupled mRNA Turnover Interaction between the Poly(A) Tail and a c-fos RNA Coding Determinant via a Protein Complex

N. Sonenberg, A. Shyu, Chyi-Ying A. Chen, 2000, Cell.

BTG/TOB factors impact deadenylases.

B. Séraphin, A. Shyu, Chyi-Ying A. Chen, 2009, Trends in biochemical sciences.

Evidence Providing New Insights into TOB-Promoted Deadenylation and Supporting a Link between TOB's Deadenylation-Enhancing and Antiproliferative Activities

A. Shyu, Chyi-Ying A. Chen, Nader Ezzeddine, 2012, Molecular and Cellular Biology.

Protein segregase meddles in remodeling of mRNA-protein complexes.

A. Shyu, Chyi-Ying A. Chen, 2013, Genes & development.

Regulation of mRNA Turnover

A. Shyu, Chyi-Ying A. Chen, 2010 .

HuD stimulates translation via eIF4A.

A. Shyu, Chyi-Ying A. Chen, 2009, Molecular cell.

Highly Selective Actions of HuR in Antagonizing AU-Rich Element-Mediated mRNA Destabilization

A. Shyu, Chyi-Ying A. Chen, N. Xu, 2002, Molecular and Cellular Biology.

Transcription termination at λ tR1 is mediated by interaction of rho with specific single-stranded domains near the 3′ end of cro mRNA

Chyi-Ying A. Chen, J. Richardson, G. Galluppi, 1986, Cell.

Ago-TNRC6 complex triggers microRNA-mediated mRNA decay by promoting biphasic deadenylation followed by decapping

A. Shyu, Chyi-Ying A. Chen, Dinghai Zheng, 2009, Nature Structural &Molecular Biology.

Ago-TNRC6 complex triggers microRNA-mediated mRNA decay by promoting biphasic deadenylation followed by decapping

A. Shyu, Chyi-Ying A. Chen, Dinghai Zheng, 2009, Nature Structural &Molecular Biology.

Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation.

J. Yates, J. Doudna, G. Hannon, 2009, Molecular cell.

Mechanisms of deadenylation‐dependent decay

A. Shyu, Chyi-Ying A. Chen, Ann-Bin Shyu, 2011, Wiley interdisciplinary reviews. RNA.

Messenger RNA half-life measurements in mammalian cells.

A. Shyu, Chyi-Ying A. Chen, Ann-Bin Shyu, 2008, Methods in enzymology.

Phosphorylation at intrinsically disordered regions of PAM2 motif-containing proteins modulates their interactions with PABPC1 and influences mRNA fate.

A. Shyu, Chyi-Ying A. Chen, Kai-Lieh Huang, 2013, RNA.

Concerted action of poly(A) nucleases and decapping enzyme in mammalian mRNA turnover

Tsung-Cheng Chang, A. Shyu, Chyi-Ying A. Chen, 2005, Nature Structural &Molecular Biology.

ROCK inhibition enhances microRNA function by promoting deadenylation of targeted mRNAs via increasing PAIP2 expression

Jiahuai Han, A. Shyu, Chyi-Ying A. Chen, 2015, Nucleic acids research.

MiR-26 down-regulates TNF-α/NF-κB signalling and IL-6 expression by silencing HMGA1 and MALT1

Jeffrey T. Chang, A. Shyu, Chyi-Ying A. Chen, 2016, Nucleic acids research.

Versatile applications of transcriptional pulsing to study mRNA turnover in mammalian cells.

Tsung-Cheng Chang, A. Shyu, Chyi-Ying A. Chen, 2007, RNA.

Unraveling regulation and new components of human P-bodies through a protein interaction framework and experimental validation.

A. Shyu, Chyi-Ying A. Chen, Dinghai Zheng, 2011, RNA.

Emerging Themes in Regulation of Global mRNA Turnover in cis.

A. Shyu, Chyi-Ying A. Chen, 2017, Trends in biochemical sciences.

Emerging mechanisms of mRNP remodeling regulation

A. Shyu, Chyi-Ying A. Chen, 2014, Wiley interdisciplinary reviews. RNA.

Deadenylation and P-bodies.

A. Shyu, Chyi-Ying A. Chen, 2013, Advances in experimental medicine and biology.

Coordinated Changes in mRNA Turnover, Translation, and RNA Processing Bodies in Bronchial Epithelial Cells following Inflammatory Stimulation

A. Shyu, Chyi-Ying A. Chen, Y. Zhai, 2008, Molecular and Cellular Biology.

Tob2 phosphorylation regulates global mRNA turnover to reshape transcriptome and impact cell proliferation

A. Shyu, Chyi-Ying A. Chen, Kai-Lieh Huang, 2020, RNA.

AU-rich elements: characterization and importance in mRNA degradation.

C. Y. Chen, A. Shyu, Chyi-Ying A. Chen, 1995, Trends in biochemical sciences.

Selective degradation of early-response-gene mRNAs: functional analyses of sequence features of the AU-rich elements

C. Y. Chen, A. Shyu, Chyi-Ying A. Chen, 1994, Molecular and cellular biology.

Unraveling a cytoplasmic role for hnRNP D in the in vivo mRNA destabilization directed by the AU-rich element.

C. Y. Chen, A. Shyu, Chyi-Ying A. Chen, 1999, Genes & development.

Interplay of two functionally and structurally distinct domains of the c-fos AU-rich element specifies its mRNA-destabilizing function

Tsuey-Ming Chen, C. Y. Chen, A. Shyu, 1994, Molecular and cellular biology.

Functional characterization of a non-AUUUA AU-rich element from the c-jun proto-oncogene mRNA: evidence for a novel class of AU-rich elements

A. Shyu, S. Peng, Chyi-Ying A. Chen, 1996, Molecular and cellular biology.

Two cellular proteins bind specifically to a purine-rich sequence necessary for the destabilization function of a c-fos protein-coding region determinant of mRNA instability

A. Shyu, Chyi-Ying A. Chen, Y. You, 1992, Molecular and cellular biology.

A broader role for AU-rich element-mediated mRNA turnover revealed by a new transcriptional pulse strategy.

A. Shyu, Chyi-Ying A. Chen, N. Xu, 1998, Nucleic acids research.

Multiple elements in the c-fos protein-coding region facilitate mRNA deadenylation and decay by a mechanism coupled to translation.

M. Greenberg, J. Belasco, A. Shyu, 1994, The Journal of biological chemistry.

Modulation of the fate of cytoplasmic mRNA by AU-rich elements: key sequence features controlling mRNA deadenylation and decay

C. Y. Chen, A. Shyu, Chyi-Ying A. Chen, 1997, Molecular and cellular biology.

mRNA decay mediated by two distinct AU-rich elements from c-fos and granulocyte-macrophage colony-stimulating factor transcripts: different deadenylation kinetics and uncoupling from translation

C. Y. Chen, A. Shyu, Chyi-Ying A. Chen, 1995, Molecular and cellular biology.

Ago-TNRC6 complex triggers microRNA-mediated mRNA decay by promoting biphasic deadenylation followed by decapping

A. Shyu, Chyi-Ying A. Chen, Dinghai Zheng, 2016 .

HuD stimulates translation via eIF4A.

A. Shyu, Chyi-Ying A. Chen, 2009, Molecular cell.