V. Imbert

发表

Hepatitis C virus NS5A and subgenomic replicon activate NF-kappaB via tyrosine phosphorylation of IkappaBalpha and its degradation by calpain protease.

A. Siddiqui, G. Waris, A. Livolsi, 2003, The Journal of biological chemistry.

Saccharomyces boulardii Interferes with Enterohemorrhagic Escherichia coli-Induced Signaling Pathways in T84 Cells

V. Imbert, J. Peyron, S. Dahan, 2003, Infection and Immunity.

, B and AP-1 in T 84 Cells κ Kinases and the Transcription Factors NF-via Activation of Mitogen-Activated Protein Infection Induces Interleukin-8 Production Escherichia coli Enterohemorrhagic

V. Imbert, J. Peyron, S. Dahan, 2001 .

GAPDH enhances the aggressiveness and the vascularization of non-Hodgkin’s B lymphomas via NF-κB-dependent induction of HIF-1α

G. Pagès, N. Mounier, V. Imbert, 2014, Leukemia.

NF‐κB/Egr‐1/Gadd45 are sequentially activated upon UVB irradiation to mediate epidermal cell death

T. Virolle, V. Imbert, J. Peyron, 2005, The EMBO journal.

Increased CD271 expression by the NF-kB pathway promotes melanoma cell survival and drives acquired resistance to BRAF inhibitor vemurafenib

P. Abbe, C. Bertolotto, R. Ballotti, 2015, Cell Discovery.

The Carcinogen Cadmium Activates Lysine 63 (K63)-Linked Ubiquitin-Dependent Signaling and Inhibits Selective Autophagy

V. Imbert, J. Peyron, Amine Belaid, 2021, Cancers.

Tyrosine phosphorylation of I kappa B-alpha activates NF-kappa B without proteolytic degradation of I kappa B-alpha.

C. Mueller-Dieckmann, P. Auberger, A. Livolsi, 1996, Cell.

Engagement of CD11b and CD11c beta2 integrin by antibodies or soluble CD23 induces IL-1beta production on primary human monocytes through mitogen-activated protein kinase-dependent pathways.

V. Imbert, R. Rezzonico, J. Dayer, 2000, Blood.

Engagement of CD 11 b and CD 11 c b 2 integrin by antibodies or soluble CD 23 induces IL-1 b production on primary human monocytes through mitogen-activated protein kinase – dependent pathways

V. Imbert, R. Rezzonico, J. Dayer, 2022 .

Induction of tyrosine phosphorylation and T-cell activation by vanadate peroxide, an inhibitor of protein tyrosine phosphatases.

P. Auberger, V. Imbert, J. Peyron, 1994, The Biochemical journal.

NF‐κB inhibition triggers death of imatinib‐sensitive and imatinib‐resistant chronic myeloid leukemia cells including T315I Bcr‐Abl mutants

V. Imbert, J. Peyron, J. Cassuto, 2009, International journal of cancer.

Monitoring NF-κB Transactivation Potential Via Real-Time PCR Quantification of IκB-α Gene Expression

V. Imbert, J. Peyron, V. Bottero, 2012, Molecular Diagnosis.

Duration of STAT5 activation influences the response of interleukin-2 receptor alpha gene to different cytokines.

V. Imbert, P. R. Renauld, 1999, European cytokine network.

Tyrosine phosphorylation-dependent activation of NF-kappa B. Requirement for p56 LCK and ZAP-70 protein tyrosine kinases.

R. Abraham, A. Livolsi, V. Imbert, 2001, European journal of biochemistry.

Constitutive activation of STAT proteins in the HDLM-2 and L540 Hodgkin lymphoma-derived cell lines supports cell survival.

V. Imbert, J. Peyron, O. Cochet, 2006, Cellular signalling.

Pharmacological inhibition of carbonic anhydrase XII interferes with cell proliferation and induces cell apoptosis in T-cell lymphomas.

Thijs J. Hagenbeek, C. Supuran, V. Imbert, 2013, Cancer letters.

Saccharomyces boulardii Modifies Salmonella Typhimurium Traffic and Host Immune Responses along the Intestinal Tract

V. Imbert, J. Peyron, P. Rampal, 2014, PloS one.

Ligation of CD11b and CD11c beta(2) integrins by antibodies or soluble CD23 induces macrophage inflammatory protein 1alpha (MIP-1alpha) and MIP-1beta production in primary human monocytes through a pathway dependent on nuclear factor-kappaB.

V. Imbert, R. Rezzonico, J. Dayer, 2001, Blood.

Hepatitis C Virus NS5A and Subgenomic Replicon Activate NF-κB via Tyrosine Phosphorylation of IκBα and Its Degradation by Calpain Protease*

A. Siddiqui, G. Waris, A. Livolsi, 2003, Journal of Biological Chemistry.

Ligation of CD11b and CD11c b 2 integrins by antibodies or soluble CD23 induces macrophage inﬂammatory protein 1 a (MIP-1 a ) and MIP-1 b production in primary human monocytes through a pathway dependent on nuclear factor– k B

V. Imbert, R. Rezzonico, R. Chicheportiche, 2001 .

Pharmacological targeting of NF-κB potentiates the effect of the topoisomerase inhibitor CPT-11 on colon cancer cells

D. Rousseau, P. Lagadec, V. Imbert, 2008, British Journal of Cancer.

Endopeptidase 24.11 (CD10/NEP) is required for phorbol ester‐induced growth arrest in Jurkat T cells

P. Auberger, V. Imbert, J. Peyron, 1997, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Thrombin and thrombin receptor agonist peptide induce early events of T cell activation and synergize with TCR cross-linking for CD69 expression and interleukin 2 production.

J. Pouysségur, P. Auberger, V. Imbert, 1994, The Journal of biological chemistry.

Targeting NF-kappaB activation via pharmacologic inhibition of IKK2-induced apoptosis of human acute myeloid leukemia cells.

V. Imbert, J. Peyron, M. Dréano, 2005, Blood.

Saccharomyces boulardii inhibits inflammatory bowel disease by trapping T cells in mesenteric lymph nodes.

A. Foussat, P. Lagadec, V. Imbert, 2006, Gastroenterology.

induced apoptosis of human acute myeloid leukemia cells B activation via pharmacological inhibition of IKK2 κ Targeting NF

V. Imbert, J. Peyron, N. Sirvent, 2013 .

Structure–function insights reveal the human ribosome as a cancer target for antibiotics

V. Imbert, J. Peyron, B. Klaholz, 2016, Nature Communications.

Senescent cells develop a PARP-1 and nuclear factor-{kappa}B-associated secretome (PNAS).

K. Bille, C. Bertolotto, R. Ballotti, 2011, Genes & Development.

Protective mitochondrial transfer from bone marrow stromal cells to acute myeloid leukemic cells during chemotherapy.

V. Imbert, J. Peyron, C. Récher, 2016, Blood.

The BMI1 polycomb protein represses cyclin G2-induced autophagy to support proliferation in chronic myeloid leukemia cells

P. Lagadec, C. Peng, V. Imbert, 2015, Leukemia.

AS602868, a dual inhibitor of IKK2 and FLT3 to target AML cells

P. Lagadec, V. Imbert, J. Peyron, 2007, Leukemia.

GAPDH Overexpression in the T Cell Lineage Promotes Angioimmunoblastic T Cell Lymphoma through an NF-κB-Dependent Mechanism.

P. Gaulard, F. Lemonnier, V. Imbert, 2019, Cancer cell.

Tyrosine Phosphorylation of IκB-α Activates NF-κB without Proteolytic Degradation of IκB-α

C. Mueller-Dieckmann, P. Auberger, A. Livolsi, 1996, Cell.

Blocking NF-κB activation in Jurkat leukemic T cells converts the survival agent and tumor promoter PMA into an apoptotic effector

P. Auberger, V. Imbert, J. Peyron, 2002, Oncogene.

Tyrosine phosphorylation‐dependent activation of NF‐κB

R. Abraham, A. Livolsi, V. Imbert, 2001 .

Inhibition of the NF-κB survival pathway via caspase-dependent cleavage of the IKK complex scaffold protein and NF-κB essential modulator NEMO

G. Courtois, K. Schulze-Osthoff, P. Auberger, 2008, Cell Death and Differentiation.

Targeting NF-κB activation via pharmacologic inhibition of IKK2-induced apoptosis of human acute myeloid leukemia cells

V. Imbert, J. Peyron, M. Dréano, 2005 .

Targeting NF-κB activation via pharmacological inhibition of IKK2 induced apoptosis of human Acute Myeloid Leukemia cells. Running title : Targeting NF-κB in Acute Myeloid Leukemias

V. Imbert, J. Peyron, M. Dréano, 2004 .

L-type amino-acid transporter 1 (LAT1): a therapeutic target supporting growth and survival of T-cell lymphoblastic lymphoma/T-cell acute lymphoblastic leukemia

Thijs J. Hagenbeek, V. Imbert, J. Peyron, 2014, Leukemia.

The metabolic perturbators metformin, phenformin and AICAR interfere with the growth and survival of murine PTEN-deficient T cell lymphomas and human T-ALL/T-LL cancer cells.

Thijs J. Hagenbeek, I. Ben-Sahra, F. Bost, 2013, Cancer letters.

miR‐483‐3p controls proliferation in wounded epithelial cells

R. Buscà, P. Barbry, V. Imbert, 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Iron chelation: an adjuvant therapy to target metabolism, growth and survival of murine PTEN-deficient T lymphoma and human T lymphoblastic leukemia/lymphoma

V. Imbert, J. Peyron, A. Popa, 2017, Leukemia & lymphoma.

Preclinical targeting of NF-κB and FLT3 pathways in AML cells

V. Imbert, J. Peyron, M. Dréano, 2008, Leukemia.

NF-κB in Hematological Malignancies

V. Imbert, J. Peyron, 2017, Biomedicines.

Induction of interleukin-2 receptor alpha (IL-2Ralpha) expression by interleukin-2: important role of the interleukin-2 receptor beta chain region between the two Stat5 docking sites.

V. Imbert, R. Rezzonico, P. Reichenbach, 2002, European cytokine network.

AS602868, a pharmacological inhibitor of IKK2, reveals the apoptotic potential of TNF-α in Jurkat leukemic cells

V. Imbert, J. Peyron, A. Loubat, 2003, Oncogene.

Frequency and Dynamics of Leukemia-Initiating Cells during Short-term Ex Vivo Culture Informs Outcomes in Acute Myeloid Leukemia Patients.

J. Gribben, A. Filby, V. Imbert, 2016, Cancer research.

Priority Frequency and dynamics of ex-vivo AML-culture initiating cells reflect patients’ outcome.

J. Gribben, A. Filby, V. Imbert, 2015 .

Calpain 2‐dependent IκBα degradation mediates CPT‐11 secondary resistance in colorectal cancer xenografts

P. Lagadec, S. Grosso, V. Imbert, 2012, The Journal of pathology.

Monitoring NF-kappa B transactivation potential via real-time PCR quantification of I kappa B-alpha gene expression.

V. Imbert, J. Peyron, V. Bottero, 2003, Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology.

Immunofluorescent quantification of tyrosine phosphorylation of cellular proteins in whole cells by flow cytometry.

V. Imbert, J. Peyron, D. F. Far, 1994, Cytometry.

Interaction of Saccharomyces boulardii with Salmonella enterica Serovar Typhimurium Protects Mice and Modifies T84 Cell Response to the Infection

P. Lagadec, V. Imbert, J. Peyron, 2010, PloS one.

accharomyces boulardii Inhibits Inflammatory Bowel Disease by rapping T Cells in Mesenteric Lymph Nodes

P. Lagadec, V. Imbert, P. Rampal, 2006 .

New Drug Repositioning Candidates for T-ALL Identified Via Human/Murine Gene Signature Comparison

P. Rohrlich, F. Reinier, V. Imbert, 2020, Frontiers in Oncology.

Stimulation of the T-cell antigen receptor-CD3 complex signaling pathway by the tyrosine phosphatase inhibitor pervanadate is mediated by inhibition of CD45: evidence for two interconnected Lck/Fyn- or zap-70-dependent signaling pathways.

P. Auberger, V. Imbert, J. Peyron, 1996, Journal of inflammation.

Inhibition of the NF-kappaB survival pathway via caspase-dependent cleavage of the IKK complex scaffold protein and NF-kappaB essential modulator NEMO.

G. Courtois, K. Schulze-Osthoff, P. Auberger, 2008, Cell death and differentiation.

Correction: Interaction of Saccharomyces boulardii with Salmonella enterica Serovar Typhimurium Protects Mice and Modifies T84 Cell Response to the Infection

V. Imbert, J. Peyron, G. Dalmasso, 2022, PloS one.

Resistance to lysosomotropic drugs used to treat kidney and breast cancers involves autophagy and inflammation and converges in inducing CXCL5

N. Rioux-Leclercq, G. Pagès, V. Imbert, 2019, Theranostics.

Human monocytes express amphiregulin and heregulin growth factors upon activation.

V. Imbert, R. Bocciardi, B. Mograbi, 1997, European cytokine network.

Co-targeting intracellular pH and essential amino acid uptake cooperates to induce cell death of T-ALL/LL cells

C. Supuran, J. Winum, V. Imbert, 2018, Leukemia & lymphoma.

Comitogenic effects of very late activation antigens on CD3-stimulated human thymocytes. Involvement of various tyrosine kinase pathways.

V. Imbert, J. Peyron, M. Deckert, 1995, Journal of Immunology.

Enterohemorrhagic Escherichia coli Infection Induces Interleukin-8 Production via Activation of Mitogen-Activated Protein Kinases and the Transcription Factors NF-κB and AP-1 in T84 Cells

V. Imbert, J. Peyron, S. Dahan, 2002, Infection and Immunity.

The metabolic perturbators metformin, phenformin and AICAR interfere with the growth and survival of murine PTEN-deficient T cell lymphomas and human T-ALL/T-LL cancer cells.

Thijs J. Hagenbeek, I. Ben-Sahra, F. Bost, 2013, Cancer letters.