C. Hoppel

C. Hoppel, L. Spry, William J. Murphy, 2012, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Decreased cytochrome c mediates an age-related decline of oxidative phosphorylation in rat kidney mitochondria.

J. O'Toole, C. Hoppel, H. Fujioka, 2010, The Biochemical journal.

A phase I and pharmacodynamic study of sequential topotecan and etoposide in patients with relapsed or refractory acute myelogenous and lymphoblastic leukemia.

S. Green, C. Hoppel, S. Gerson, 2003, Leukemia research.

A phase II and pharmacokinetic study of weekly 72-h topotecan infusion in patients with platinum-resistant and paclitaxel-resistant ovarian carcinoma.

C. Hoppel, P. Rose, S. Ingalls, 2000, Gynecologic oncology.

Dynamic organization of mitochondria in human heart and in myocardial disease.

C. Hoppel, B. Tandler, H. Fujioka, 2009, The international journal of biochemistry & cell biology.

Bioenergetic functions in subpopulations of heart mitochondria are preserved in a non-obese type 2 diabetes rat model (Goto-Kakizaki)

C. Hoppel, F. Loy, R. Isola, 2020, Scientific Reports.

Cardiac mitochondria in heart failure: normal cardiolipin profile and increased threonine phosphorylation of complex IV.

C. Hoppel, Mariana G Rosca, P. Minkler, 2011, Biochimica et biophysica acta.

Isolation and identification of two isomeric forms of malonyl-coenzyme A in commercial malonyl-coenzyme A.

N. Maiti, C. Hoppel, V. Anderson, 2004, Analytical biochemistry.

A phase IB clinical and pharmacokinetic study of the angiogenesis inhibitor SU5416 and paclitaxel in recurrent or metastatic carcinoma of the head and neck

B. Overmoyer, C. Hoppel, M. Cooney, 2005, Cancer Chemotherapy and Pharmacology.

Integrated mitochondrial function and cancer-related fatigue in men with prostate cancer undergoing radiation therapy

C. Hoppel, B. Daly, C. Hsiao, 2018, Cancer management and research.

Phosphorylation of Rat Liver Mitochondrial Carnitine Palmitoyltransferase-I

C. Hoppel, S. Peterman, W. Parland, 2004, Journal of Biological Chemistry.

Mitochondria in Cardiovascular Physiology and Disease Enhanced resistance to permeability transition in interfibrillar cardiac mitochondria in dogs : effects of aging and long-term aldosterone infusion

C. Hoppel, H. Sabbah, P. Hecker, 2013 .

Effect of theophylline on urinary excretion of 3-methylhistidine in patients with lung disease.

E. R. Mcfadden, C. Hoppel, I. Wei, 1991, Metabolism: clinical and experimental.

Competition between acetate and oleate for the formation of malonyl-CoA and mitochondrial acetyl-CoA in the perfused rat heart.

C. Hoppel, H. Brunengraber, V. Anderson, 2006, Journal of molecular and cellular cardiology.

Mitochondrial dysfunction in heart failure

C. Hoppel, Mariana G Rosca, M. Rosca, 2013, Heart Failure Reviews.

New aspects of impaired mitochondrial function in heart failure

C. Hoppel, Mariana G Rosca, M. Rosca, 2009, Journal of bioenergetics and biomembranes.

Enhanced acyl-CoA dehydrogenase activity is associated with improved mitochondrial and contractile function in heart failure.

M. Chandler, B. Hoit, C. Hoppel, 2008, Cardiovascular research.

Diabetes or peroxisome proliferator-activated receptor alpha agonist increases mitochondrial thioesterase I activity in heart.

C. Hoppel, K. O’Shea, Hazel Huang, 2007, Journal of lipid research.

Diabetes or peroxisome proliferator-activated receptor α agonist increases mitochondrial thioesterase I activity in heart Published, JLR Papers in Press, April 16, 2007.

C. Hoppel, K. O’Shea, Hazel Huang, 2007, Journal of Lipid Research.

Peroxisomal Fatty Acid Oxidation Is a Substantial Source of the Acetyl Moiety of Malonyl-CoA in Rat Heart*

C. Hoppel, H. Brunengraber, C. Des Rosiers, 2004, Journal of Biological Chemistry.

Radiochemical malonyl-CoA decarboxylase assay: activity and subcellular distribution in heart and skeletal muscle.

C. Hoppel, J. Kerner, 2002, Analytical biochemistry.

Assessing the Reversibility of the Anaplerotic Reactions of the Propionyl-CoA Pathway in Heart and Liver*

C. Hoppel, H. Brunengraber, C. Des Rosiers, 2003, Journal of Biological Chemistry.

Mitochondrial Utilization of Competing Fuels Is Altered in Insulin Resistant Skeletal Muscle of Non-obese Rats (Goto-Kakizaki)

C. Hoppel, C. Fealy, J. Kirwan, 2020, Frontiers in Physiology.

Isolation of mitochondrial subpopulations from skeletal muscle: Optimizing recovery and preserving integrity

C. Hoppel, B. Tandler, H. Fujioka, 2018, Acta physiologica.

L-carnitine enhances excretion of propionyl coenzyme A as propionylcarnitine in propionic acidemia.

T. Bohan, C. Hoppel, D. Maltby, 1984, The Journal of clinical investigation.

Cardiolipin: characterization of distinct oxidized molecular species

C. Hoppel, V. Anderson, R. G. Salomon, 2011, Journal of Lipid Research.

Design and implementation of the first randomized controlled trial of coenzyme CoQ₁₀ in children with primary mitochondrial diseases.

D. Kerr, T. Degrauw, C. Hoppel, 2012, Mitochondrion.

Glutaredoxin regulates apoptosis in cardiomyocytes via NFkappaB targets Bcl-2 and Bcl-xL: implications for cardiac aging.

C. Hoppel, M. Gallogly, J. Mieyal, 2010, Antioxidants & redox signaling.

The Malonyl-CoA-sensitive Form of Carnitine Palmitoyltransferase Is Not Localized Exclusively in the Outer Membrane of Rat Liver Mitochondria*

C. Hoppel, B. Tandler, J. Kerner, 1998, The Journal of Biological Chemistry.

What is the functional significance of the unique location of glutaredoxin 1 (GRx1) in the intermembrane space of mitochondria?

C. Hoppel, J. Mieyal, E. Lesnefsky, 2007, Antioxidants & redox signaling.

Studies on Giant Mitochondria

C. Hoppel, B. Tandler, 1986, Annals of the New York Academy of Sciences.

Metabolic response to carnitine in methylmalonic aciduria. An effective strategy for elimination of propionyl groups.

C. Hoppel, D. Millington, C. Roe, 1983, Archives of disease in childhood.

Sterol Regulatory Element-binding Protein-1 (SREBP-1) Is Required to Regulate Glycogen Synthesis and Gluconeogenic Gene Expression in Mouse Liver*

A. Depaoli-Roach, P. Roach, C. Hoppel, 2014, The Journal of Biological Chemistry.

Plasma and Urine Carnitine in Diabetic Ketosis

S. Genuth, C. Hoppel, 1979, Diabetes.

Peroxisome Proliferator-activated Receptor γ (PPARγ) Mediates a Ski Oncogene-induced Shift from Glycolysis to Oxidative Energy Metabolism*♦

C. Hoppel, Fanghua Ye, M. Puchowicz, 2011, The Journal of Biological Chemistry.

Novel isolation procedure for short-, medium-, and long-chain acyl-coenzyme A esters from tissue.

C. Hoppel, S. Ingalls, J. Kerner, 2008, Analytical biochemistry.

Quantification of carnitine and acylcarnitines in biological matrices by HPLC electrospray ionization-mass spectrometry.

C. Hoppel, S. Ingalls, J. Kerner, 2008, Clinical chemistry.

Mitochondrial Division in Rat Cardiomyocytes: An Electron Microscope Study

C. Hoppel, B. Tandler, H. Fujioka, 2011, Anatomical record.

Quantification of malonyl-coenzyme A in tissue specimens by high-performance liquid chromatography/mass spectrometry.

C. Hoppel, T. Kasumov, W. Parland, 2006, Analytical biochemistry.

Elevated Plasma Carnitine in Hepatic Cirrhosis

C. Hoppel, R. Fuller, 2007, Hepatology.

A radiochemical pyruvate dehydrogenase assay: activity in heart.

C. Hoppel, W. Stanley, J. Kerner, 2003, Analytical biochemistry.

Kruppel-like Factor 15 Is a Critical Regulator of Cardiac Lipid Metabolism*

Saptarsi M. Haldar, T. Tuschl, C. Hoppel, 2014, The Journal of Biological Chemistry.

Mitochondrial uncoupling attenuates sarcopenic obesity by enhancing skeletal muscle mitophagy and quality control

C. Hoppel, J. Kirwan, Yongmei Yu, 2022, Journal of cachexia, sarcopenia and muscle.

Metabolic reprogramming during hyperammonemia targets mitochondrial function and postmitotic senescence

C. Hoppel, A. Kerr, S. Dasarathy, 2021, JCI insight.

Aging skeletal muscle mitochondria in the rat: decreased uncoupling protein-3 content.

C. Hoppel, J. Kerner, P. Minkler, 2001, American journal of physiology. Endocrinology and metabolism.

Acetyl-l-carnitine increases mitochondrial protein acetylation in the aged rat heart

M. Chance, C. Hoppel, Kwangwon Lee, 2015, Mechanisms of Ageing and Development.

Quantification of carnitine, acetylcarnitine, and total carnitine in tissues by high-performance liquid chromatography: the effect of exercise on carnitine homeostasis in man.

C. Hoppel, W. Hiatt, S. Ingalls, 1995, Analytical biochemistry.

Carnitine palmitoyltransferase in bovine fetal heart mitochondria.

C. Hoppel, R. Tomec, 1975, Archives of biochemistry and biophysics.

Fatty Acid Chain Elongation in Palmitate-perfused Working Rat Heart

C. Hoppel, E. Lesnefsky, J. Kerner, 2014, The Journal of Biological Chemistry.

Carnitine metabolism in the fasting rat.

C. Hoppel, E. Brass, 1978, The Journal of biological chemistry.

Mitochondrial Dysfunction in Cardiovascular Aging.

C. Hoppel, B. Tandler, Qun Chen, 2017, Advances in experimental medicine and biology.

Decreased Cytochrome c Oxidase Subunit VIIa in Aged Rat Heart Mitochondria: Immunocytochemistry

D. Murdock, C. Hoppel, B. Tandler, 2011, Anatomical record.

Structure of cristae in cardiac mitochondria of aged rat

C. Hoppel, B. Tandler, Edwin J. Vazquez, 2006, Mechanisms of Ageing and Development.

Blockade of Electron Transport before Cardiac Ischemia with the Reversible Inhibitor Amobarbital Protects Rat Heart Mitochondria

C. Hoppel, Qun Chen, E. Lesnefsky, 2006, Journal of Pharmacology and Experimental Therapeutics.

Interfibrillar cardiac mitochondrial comples III defects in the aging rat heart

C. Hoppel, S. Moghaddas, E. Lesnefsky, 2004, Biogerontology.

Ischemia-reperfusion injury in the aged heart: role of mitochondria.

C. Hoppel, E. Lesnefsky, 2003, Archives of biochemistry and biophysics.

Preservation of cardiolipin content during aging in rat heart interfibrillar mitochondria.

C. Hoppel, S. Moghaddas, E. Lesnefsky, 2002, The journals of gerontology. Series A, Biological sciences and medical sciences.

Giant Mitochondria in a Cardiomyopathic Heart

C. Hoppel, B. Tandler, M. Dunlap, 2002, Ultrastructural pathology.

Determination of free trimethyllysine in plasma and tissue specimens by high-performance liquid chromatography.

C. Hoppel, S. Ingalls, A. Davis, 1984, Journal of chromatography.

Hepatic mitochondrial function in ketogenic states. Diabetes, starvation, and after growth hormone administration.

C. Hoppel, J. DiMarco, 1975, The Journal of clinical investigation.

Liver Gluconeogenic Gene Expression in Mouse Regulate Glycogen Synthesis and Protein-1 ( SREBP-1 ) Is Required to Sterol Regulatory Element-binding Gene Regulation :

A. Depaoli-Roach, P. Roach, C. Hoppel, 2014 .

Hyperammonaemia‐induced skeletal muscle mitochondrial dysfunction results in cataplerosis and oxidative stress

D. V. Van Wagoner, C. Flask, C. Hoppel, 2016, The Journal of physiology.

Kruppel-like factor 15 regulates skeletal muscle lipid flux and exercise adaptation

Saptarsi M. Haldar, A. Russell, D. Jeyaraj, 2012, Proceedings of the National Academy of Sciences.

O6-benzylguanine: a clinical trial establishing the biochemical modulatory dose in tumor tissue for alkyltransferase-directed DNA repair.

J. Haaga, J. Willson, C. Hoppel, 1999, Cancer research.

Oxidation of Fatty Acids Is the Source of Increased Mitochondrial Reactive Oxygen Species Production in Kidney Cortical Tubules in Early Diabetes

C. Hoppel, T. Kern, Qun Chen, 2012, Diabetes.

Effect of intravenous L‐carnitine on carnitine homeostasis and fuel metabolism during exercise in humans

C. Hoppel, W. Hiatt, E. Brass, 1994, Clinical pharmacology and therapeutics.

Effect of starvation in the rat on trimethyllysine in peptide linkage.

C. Hoppel, A. Davis, 1983, The Journal of nutrition.

Rat liver mitochondrial carnitine palmitoyltransferase-I, hepatic carnitine, and malonyl-CoA: Effect of starvation

C. Hoppel, W. Parland, J. Kerner, 2008, Archives of physiology and biochemistry.

Systemic Deficiency of the First Component of the Pyruvate Dehydrogenase Complex

D. Kerr, C. Hoppel, J. Towfighi, 1987, Pediatric Research.

Decreased NADH dehydrogenase and ubiquinol-cytochrome c oxidoreductase in peripheral arterial disease.

C. Hoppel, A. Gardner, W. Hiatt, 2001, American journal of physiology. Heart and circulatory physiology.

Carnitine palmityltransferase. Location of two enzymatic activities in rat liver mitochondria.

C. Hoppel, R. Tomec, 1972, The Journal of biological chemistry.

Urinary excretion of acetylcarnitine during human diabetic and fasting ketosis.

S. Genuth, C. Hoppel, C L Hoppel, 1982, The American journal of physiology.

Carnitine metabolism in lean and obese Zucker rats during starvation.

C. Hoppel, L. Brady, A. Davis, 1986, The Journal of nutrition.

Relationship between acid-soluble carnitine and coenzyme A pools in vivo.

C. Hoppel, E. Brass, 1980, The Biochemical journal.

Effect of carnitine on mitochondrial oxidation of palmitoylearnitine.

C. Hoppel, E. Brass, 1980, The Biochemical journal.

Biosynthesis of carnitine and 4-N-trimethylaminobutyrate from lysine.

R. A. Cox, C. Hoppel, 1973, The Biochemical journal.

Comprehensive approach to the quantitative analysis of mitochondrial phospholipids by HPLC-MS.

C. Hoppel, Junhwan Kim, 2013, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Improved Mitochondrial Function with Diet-Induced Increase in Either Docosahexaenoic Acid or Arachidonic Acid in Membrane Phospholipids

C. Hoppel, K. O’Shea, C. Rosiers, 2012, PloS one.

Lethal neonatal deficiency of carnitine palmitoyltransferase II associated with dysgenesis of the brain and kidneys.

U. de Girolami, U. Girolami, K. North, 1995, The Journal of pediatrics.

Determination of 6-N-trimethyllysine in urine by high-performance liquid chromatography.

F. M. Brown, C. Hoppel, S. Ingalls, 1983, Journal of chromatography.

A Phase I and Pharmacodynamic Study of Fludarabine, Carboplatin, and Topotecan in Patients With Relapsed, Refractory, or High-Risk Acute Leukemia

M. Tilby, C. Hoppel, S. Gerson, 2004, Clinical Cancer Research.

Biochemical differences between subsarcolemmal and interfibrillar mitochondria from rat cardiac muscle: effects of procedural manipulations.

C. Hoppel, B. Tandler, J. Palmer, 1985, Archives of biochemistry and biophysics.

The M405V allele of the glutaryl-CoA dehydrogenase gene is an important marker for glutaric aciduria type I (GA-I) low excretors.

G. Enns, C. Hoppel, J. Bedoyan, 2016, Molecular genetics and metabolism.

Functional redundancy of mitochondrial enoyl‐CoA isomerases in the oxidation of unsaturated fatty acids

R. Wanders, C. Hoppel, J. Sass, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Carnitine and carnitine palmitoyltransferase in fatty acid oxidation and ketosis.

C. Hoppel, 1982, Federation proceedings.

Elevated hepatic mitochondrial and peroxisomal oxidative capacities in fed and starved adult obese (ob/ob) mice.

C. Hoppel, L. Brady, D. Romsos, 1985, The Biochemical journal.

cis-3,4-Methylene-heptanoylcarnitine: characterization and verification of the C8:1 acylcarnitine in human urine.

C. Hoppel, P. Minkler, Shuming Yang, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Strategy for the isolation, derivatization, chromatographic separation, and detection of carnitine and acylcarnitines.

C. Hoppel, S. Ingalls, P. Minkler, 2005, Analytical chemistry.

Measuring oxidative phosphorylation in human skin fibroblasts.

C. Hoppel, Fanghua Ye, 2013, Analytical biochemistry.

Development of B -Lapachone Prodrugs forTherapyAgainst Human Cancer Cells with Elevated NAD(P)H:Quinone Oxidoreductase 1Levels Cancer Therapy: Preclinical

Jinming Gao, D. Boothman, J. Pink, 2005 .

DIVISION OF GIANT MITOCHONDRIA DURING RECOVERY FROM CUPRIZONE INTOXICATION

C. Hoppel, B. Tandler, 1973, The Journal of cell biology.

Quantitation of long-chain acylcarnitines by HPLC/fluorescence detection: application to plasma and tissue specimens from patients with carnitine palmitoyltransferase-II deficiency.

K. North, C. Hoppel, J. Kerner, 2005, Clinica chimica acta; international journal of clinical chemistry.

Impact on carnitine homeostasis of short‐term treatment with the pivalate prodrug cefditoren pivoxil

C. Hoppel, E. Brass, D. Mulford, 2003, Clinical pharmacology and therapeutics.

Urinary 3-hydroxyadipic acid 3,6-lactone: structural identification and effect of fasting in adults and children.

D. Kerr, S. Genuth, C. Hoppel, 1989, Metabolism: clinical and experimental.

Metabolic Studies of Carnitine in a Child with Propionic Acidemia

C. Hoppel, P. Goldblatt, T. Kurczynski, 1989, Pediatric Research.

Plasma acylcarnitine profiles suggest incomplete long-chain fatty acid beta-oxidation and altered tricarboxylic acid cycle activity in type 2 diabetic African-American women.

C. Hoppel, J. Newman, W. Garvey, 2009, The Journal of nutrition.

Quantitative acylcarnitine determination by UHPLC-MS/MS--Going beyond tandem MS acylcarnitine "profiles".

C. Hoppel, S. Ingalls, J. Kerner, 2015, Molecular genetics and metabolism.

Mitochondrial Dysfunction in a Patient with Crohn Disease: Possible Role in Pathogenesis

C. Hoppel, I. Schafer, M. Srivastava, 2004, Journal of pediatric gastroenterology and nutrition.

Megamitochondria in Cardiomyocytes of a Knockout (Klf15−/−) Mouse

Saptarsi M. Haldar, C. Hoppel, B. Tandler, 2015, Ultrastructural pathology.

Blockade of Electron Transport during Ischemia Protects Cardiac Mitochondria*

C. Hoppel, B. Tandler, Qun Chen, 2004, Journal of Biological Chemistry.

In vivo studies of carnitine and fatty acid metabolism: problems with use of anesthetics.

C. Hoppel, E. Brass, 1981, Analytical biochemistry.

String mitochondria in mouse soleus muscle

Saptarsi M. Haldar, C. Hoppel, B. Tandler, 2013, Microscopy research and technique.

Rat liver mitochondrial contact sites and carnitine palmitoyltransferase-I.

C. Hoppel, B. Tandler, J. Kerner, 2001, Archives of biochemistry and biophysics.

Analyzing mitochondrial function in human peripheral blood mononuclear cells.

C. Hoppel, C. Hsiao, 2018, Analytical biochemistry.

Isolation of hepatic mitochondrial contact sites: previously unrecognized inner membrane components.

C. Hoppel, B. Tandler, J. Kerner, 2002, Analytical biochemistry.

Biochemical effects of cuprizone on mouse liver and heart mitochondria.

C. Hoppel, B. Tandler, 1973, Biochemical pharmacology.

Evidence for compartmentalization of mammalian carotenoid metabolism

C. Hoppel, J. Amengual, J. Lintig, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The failure of supplemental dietary copper to prevent cuprizone-induced alterations in mouse hepatocytes.

C. Hoppel, B. Tandler, 1975, Beitrage zur Pathologie.

71 Ischemic damage to the electron transport chain increases the production of reactive oxygen species from isolated rat heart mitochondria

C. Hoppel, Qun Chen, S. Moghaddas, 2007 .

Fatty acid oxidation in cardiac and skeletal muscle mitochondria is unaffected by deletion of CD36.

C. Hoppel, M. Febbraio, W. Stanley, 2007, Archives of biochemistry and biophysics.

DIABETES, STARVATION, AND AFTER GROWTH HORMONE ADMINISTRATION

C. Hoppel, J. DiMarco, 1975 .

Probing peroxisomal β-oxidation and the labelling of acetyl-CoA proxies with [1-13C]octanoate and [3-13C]octanoate in the perfused rat liver

C. Hoppel, H. Brunengraber, T. Kasumov, 2005 .

Probing peroxisomal beta-oxidation and the labelling of acetyl-CoA proxies with [1-(13C)]octanoate and [3-(13C)]octanoate in the perfused rat liver.

C. Hoppel, H. Brunengraber, F. David, 2005, The Biochemical journal.

Partial deficiency of muscle carnitine palmitoyltransferase with normal ketone production.

C. Hoppel, K. Hostetler, J. Romine, 1978, The New England journal of medicine.

Rapid and sensitive method for the determination of salicylic acid in serum by reversed-phase ion-pair high-performance liquid chromatography.

C. Hoppel, S. Ingalls, W. Forman, 1983, Journal of chromatography.

Selective, Accurate, and Precise Quantitation of Glutarylcarnitine in Human Urine from a Patient with Glutaric Acidemia Type I.

C. Hoppel, S. Ingalls, P. Minkler, 2017, The journal of applied laboratory medicine.

Selective and accurate C5 acylcarnitine quantitation by UHPLC-MS/MS: Distinguishing true isovaleric acidemia from pivalate derived interference.

C. Hoppel, S. Ingalls, P. Minkler, 2017, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Correcting false positive medium-chain acyl-CoA dehydrogenase deficiency results from newborn screening; synthesis, purification, and standardization of branched-chain C8 acylcarnitines for use in their selective and accurate absolute quantitation by UHPLC-MS/MS.

C. Hoppel, S. Ingalls, P. Minkler, 2017, Molecular genetics and metabolism.

Oxidative phosphorylation analysis: assessing the integrated functional activity of human skeletal muscle mitochondria--case studies.

D. Kerr, C. Hoppel, M. Puchowicz, 2004, Mitochondrion.

A 22 kDa polyanion inhibits carnitine‐dependent fatty acid oxidation in rat liver mitochondria

C. Hoppel, J. Kerner, P. Turkaly, 1999, FEBS letters.

Development and evaluation of a spectrophotometric assay for complex III in isolated mitochondria, tissues and fibroblasts from rats and humans.

S. Krähenbühl, C. Hoppel, U. Wiesmann, 1994, Clinica chimica acta; international journal of clinical chemistry.

Pharmacologic action of L-carnitine on hypertriglyceridemia in obese Zucker rats.

C. Hoppel, L. Brady, C. Leathers, 1986, Metabolism: clinical and experimental.

Multiple Muscle Cell Alterations in a Case of Encephalomyopathy

Mark L. Cohen, C. Hoppel, B. Tandler, 2014, Ultrastructural pathology.

Phase II and pharmacokinetic/pharmacodynamic trial of sequential topoisomerase I and II inhibition with topotecan and etoposide in advanced non-small-cell lung cancer

N. Berger, C. Hoppel, A. Dowlati, 2000, Cancer Chemotherapy and Pharmacology.

Carnitine palmitoyltransferase activity in the rabbit choroid plexus: Its possible function in fatty acid metabolism and transport

C. Hoppel, Chung-Sei Kim, 1992, Neuroscience Letters.

Separation of acylcarnitines from biological samples using high-performance liquid chromatography.

C. Hoppel, E. Brass, A. Gibbons, 1986, Analytical biochemistry.

Management of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone-induced methemoglobinemia.

C. Hoppel, S. Ingalls, T. Radivoyevitch, 2012, Future oncology.

The role of carnitine in normal and altered fatty acid metabolism.

C. Hoppel, 2003, American journal of kidney diseases : the official journal of the National Kidney Foundation.

Furosemide kinetics in patients with hepatic cirrhosis with ascites

C. Hoppel, R. Fuller, S. Ingalls, 1981, Clinical pharmacology and therapeutics.

Cardiac mitochondria in heart failure: decrease in respirasomes and oxidative phosphorylation

William Stanley, Hani N. Sabbah, Charles L. Hoppel, 2008, Cardiovascular research.

Monolysocardiolipin: improved preparation with high yield

C. Hoppel, Junhwan Kim, 2011, Journal of Lipid Research.

Improvements in lipoatrophy, mitochondrial DNA levels and fat apoptosis after replacing stavudine with abacavir or zidovudine

C. Hoppel, G. McComsey, C. Cherry, 2005, AIDS.

Hepatic mitochondrial inner membrane properties and carnitine palmitoyltransferase A and B. Effect of diabetes and starvation.

C. Hoppel, L. Brady, P. Brady, 1985, The Biochemical journal.

Hepatic peroxisomal and mitochondrial fatty acid oxidation in the riboflavin-deficient rat.

C. Hoppel, P. Brady, 1985, The Biochemical journal.

Peroxisomal palmitoyl-CoA oxidation in the Zucker rat.

C. Hoppel, P. Brady, 1983, The Biochemical journal.

Carnitine Palmitoyltransferase and Transport of Fatty Acids

C. Hoppel, 1976 .

CARNITINE AND CARNITINE PALMITOYLTRANSFERASE IN METABOLIC STUDIES1

S. Genuth, C. Hoppel, R. Fuller, 1980 .

Acyl-CoA dehydrogenase activity in the riboflavin-deficient rat. Effects of starvation.

C. Hoppel, N. S. Ross, 1987, The Biochemical journal.

Effect of diet and starvation on hepatic mitochondrial function in the rat.

C. Hoppel, L. Brady, 1983, The Journal of nutrition.

Hepatic mitochondrial function in lean and obese Zucker rats.

C. Hoppel, L. Brady, 1983, The American journal of physiology.

Trimethyllysine metabolism in lean and obese zucker rats during fasting

C. Hoppel, L. Brady, A. Davis, 1987 .

Parkinson’s disease-associated mutant VPS35 causes mitochondrial dysfunction by recycling DLP1 complexes

Wenzhang Wang, Xiongwei Zhu, C. Hoppel, 2015, Nature Medicine.

Plasma Citrate and Succinate Are Associated with Neurocognitive Impairment in Older People with HIV.

R. Ellis, F. Palella, C. Hoppel, 2021, Clinical Infectious Diseases.

Mitochondria in cardiac hypertrophy and heart failure.

C. Hoppel, B. Tandler, M. Rosca, 2013, Journal of molecular and cellular cardiology.

Quantification of carnitine and specific acylcarnitines by high-performance liquid chromatography: application to normal human urine and urine from patients with methylmalonic aciduria, isovaleric acidemia or medium-chain acyl-CoA dehydrogenase deficiency.

C. Hoppel, P. Minkler, 1993, Journal of chromatography.

Mitochondrial Metabolism in Aging Heart.

C. Hoppel, Qun Chen, E. Lesnefsky, 2016, Circulation research.

Fatty acid chain‐elongation in perfused rat heart: Synthesis of stearoylcarnitine from perfused palmitate

C. Hoppel, E. Lesnefsky, J. Kerner, 2007, FEBS letters.

Derivatization of carboxylic acids by reaction with 4'-bromophenacyl trifluoromethanesulfonate prior to determination by high-performance liquid chromatography.

C. Hoppel, S. Ingalls, J. Nordlander, 1984, Journal of chromatography.

Synthesis and characterization of cis-4-decenoyl-CoA, 3-phenylpropionyl-CoA, and 2,6-dimethylheptanoyl-CoA.

C. Hoppel, H. Sobhi, P. Minkler, 2010, Analytical biochemistry.

Abnormal urinary excretion of unsaturated dicarboxylic acids in patients with medium-chain acyl-CoA dehydrogenase deficiency.

D. Kerr, C. Hoppel, K. Tserng, 1990, Journal of lipid research.

Validated method for the quantification of free and total carnitine, butyrobetaine, and acylcarnitines in biological samples.

C. Hoppel, S. Ingalls, J. Kerner, 2015, Analytical chemistry.

High-performance liquid chromatographic separation of acylcarnitines following derivatization with 4′-bromophenacyl trifluromethanesulfonate

C. Hoppel, S. Ingalls, P. Minkler, 1990 .

L-Carnitine insufficiency in disorders of organic acid metabolism: response to L-carnitine by patients with methylmalonic aciduria and 3-hydroxy-3-methylglutaric aciduria.

C. Hoppel, D. Millington, C. Roe, 1984, Journal of inherited metabolic disease.

Incomplete fatty acid oxidation. The production and epimerization of 3-hydroxy fatty acids.

C. Hoppel, K. Tserng, S. Jin, 1992, The Journal of biological chemistry.

Successful long-term treatment of hepatic carnitine palmitoyltransferase I deficiency and a novel mutation

J. Stoler, C. Hoppel, V. Shih, 2004, Journal of Inherited Metabolic Disease.

Secondary carnitine insufficiency in disorders of organic acid metabolism: modulation of acyl-CoA/CoA ratios by l-carnitine in vivo

C. Hoppel, D. Millington, C. Roe, 1983 .

Modulation of electron transport protects cardiac mitochondria and decreases myocardial injury during ischemia and reperfusion.

C. Hoppel, A. Camara, D. Stowe, 2007, American journal of physiology. Cell physiology.

Determination of carnitine, butyrobetaine, and betaine as 4'-bromophenacyl ester derivatives by high-performance liquid chromatography.

C. Hoppel, S. Ingalls, L. Kormoš, 1984, Journal of chromatography.

Mitochondrial defects and anesthetic sensitivity.

C. Hoppel, P. Morgan, M. Sedensky, 2002, Anesthesiology.

Effect of Ibuprofen on Neutrophil Migration in Vivo in Cystic Fibrosis and Healthy Subjects

C. Hoppel, M. Konstan, P. Davis, 2003, Journal of Pharmacology and Experimental Therapeutics.

Mutations in the mitochondrial ribosomal protein MRPS22 lead to primary ovarian insufficiency

J. Lupski, S. Jhangiani, C. Hodges, 2018, Human molecular genetics.

Bupivacaine Inhibits Acylcarnitine Exchange in Cardiac Mitochondria

G. Edelman, C. Hoppel, G. Weinberg, 2000, Anesthesiology.

Synthesis of radioactively methyl-labelled (l)-carnitine

C. Hoppel, S. Ingalls, J. Turkaly, 1982 .

Synthesis of carboxy-labelled l-carnitine

C. Hoppel, D. Goodfellow, J. Turkaly, 1982 .

Pharmacokinetics of O6‐Benzylguanine (NSC637037) and Its Metabolite, 8‐Oxo‐O6‐Benzylguanine

J. Willson, C. Hoppel, S. Gerson, 2003, Journal of clinical pharmacology.

Mitochondrial Oxidative Phosphorylation Is Defective in the Long-lived Mutant clk-1*

C. Hoppel, E. Kayser, P. Morgan, 2004, Journal of Biological Chemistry.

Simultaneous determination of O6-benzylguanine and 8-oxo-O6-benzylguanine in human plasma by reversed-phase high-performance liquid chromatography.

J. Willson, C. Hoppel, S. Gerson, 1997, Journal of chromatography. B, Biomedical sciences and applications.

Determination of O6-benzylguanine in human plasma by reversed-phase high-performance liquid chromatography.

J. Willson, C. Hoppel, S. Gerson, 1996, Journal of chromatography. B, Biomedical applications.

A Clinical Trial Establishing the Biochemical Modulatory Dose in Tumor Tissue for Alkyltransferase-directed DNA Repair 1

J. Haaga, J. Willson, Lili Liu, 1999 .

Biochemical properties of subsarcolemmal and interfibrillar mitochondria isolated from rat cardiac muscle.

C. Hoppel, B. Tandler, J W Palmer, 1977, The Journal of biological chemistry.

Fatty acid import into mitochondria.

C. Hoppel, J Kerner, C Hoppel, 2000, Biochimica et biophysica acta.

Structural differences in two biochemically defined populations of cardiac mitochondria.

C. Hoppel, B. Tandler, Edwin J. Vazquez, 2005, American journal of physiology. Heart and circulatory physiology.

Determination of free carnitine and 'total' carnitine in human urine: derivatization with 4'-bromophenacyl trifluoromethanesulfonate and high performance liquid chromatography.

C. Hoppel, P. Minkler, 1992, Clinica chimica acta; international journal of clinical chemistry.

Biosynthesis of carnitine and 4-N-trimethylaminobutyrate from 6-N-trimethyl-lysine.

R. A. Cox, C. Hoppel, 1973, The Biochemical journal.

The Failing Heart Relies on Ketone Bodies as a Fuel

Rick B. Vega, E. Lewandowski, C. Hoppel, 2016, Circulation.

Mitochondrial Dysfunction and Myocardial Ischemia-Reperfusion: Implications for Novel Therapies.

C. Hoppel, B. Tandler, Qun Chen, 2017, Annual review of pharmacology and toxicology.

VDAC proteomics: post-translation modifications.

C. Hoppel, B. Tandler, Kwangwon Lee, 2012, Biochimica et biophysica acta.

A mitochondrial enzyme degrades carotenoids and protects against oxidative stress

K. Palczewski, C. Hoppel, M. Golczak, 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Determination of ibuprofen in human plasma by high-performance liquid chromatography.

C. Hoppel, P. Minkler, 1988, Journal of chromatography.

Breast cancer growth and proliferation is suppressed by the mitochondrial targeted furazano[3,4-b]pyrazine BAM15

Shengping Yang, C. Hoppel, K. Hoehn, 2021, Cancer & metabolism.

Proteomics of mitochondrial inner and outer membranes

C. Hoppel, A. Distler, J. Kerner, 2008, Proteomics.

A targeted proteomic approach for the analysis of rat liver mitochondrial outer membrane proteins with extensive sequence coverage.

C. Hoppel, S. Peterman, A. Distler, 2006, Analytical biochemistry.

Post-translational modifications of mitochondrial outer membrane proteins.

C. Hoppel, Kwangwon Lee, A. Distler, 2009, Methods in enzymology.

Post-translational modifications of rat liver mitochondrial outer membrane proteins identified by mass spectrometry.

C. Hoppel, A. Distler, J. Kerner, 2007, Biochimica et biophysica acta.

Alterations of skeletal muscle bioenergetics in a mouse with F508del mutation leading to a cystic fibrosis-like condition.

M. Drumm, C. Hoppel, N. Lai, 2019, American journal of physiology. Endocrinology and metabolism.

HIF drives lipid deposition and cancer in ccRCC via repression of fatty acid metabolism

S. Welford, B. Rini, S. Campbell, 2017, Nature Communications.

Cited2, a Transcriptional Modulator Protein, Regulates Metabolism in Murine Embryonic Stem Cells*

S. Dunwoodie, C. Hoppel, Fanghua Ye, 2013, The Journal of Biological Chemistry.

Oxidative phosphorylation and aging

C. Hoppel, E. Lesnefsky, 2006, Ageing Research Reviews.

HIF drives lipid deposition and cancer in ccRCC via repression of fatty acid metabolism

S. Welford, B. Rini, S. Campbell, 2017, Nature Communications.

Homozygous carnitine palmitoyltransferase 1b (muscle isoform) deficiency is lethal in the mouse.

P. A. Wood, T. Schoeb, C. Hoppel, 2005, Molecular genetics and metabolism.

Improved Metabolic Health Alters Host Metabolism in Parallel with Changes in Systemic Xeno-Metabolites of Gut Origin

Gretchen A. Casazza, Oliver Fiehn, Caitlin Campbell, 2014, PloS one.

Blocked O-GlcNAc cycling alters mitochondrial morphology, function, and mass

C. Hoppel, J. Hanover, J. Mears, 2021, Scientific Reports.

Characterization of D-3-hydroxybutyrylcarnitine (ketocarnitine): an identified ketosis-induced metabolite.

R. Wanders, M. Durán, C. Hoppel, 2012, Metabolism: clinical and experimental.

Ultrastructural effects of dietary galactoflavin on mouse hepatocytes.

C. Hoppel, B. Tandler, 1974, Experimental and molecular pathology.

Carnitine and trimethylaminobutyrate synthesis in rat tissues.

R. A. Cox, C. Hoppel, 1974, The Biochemical journal.

Mitochondria in the elderly: Is acetylcarnitine a rejuvenator?

C. Hoppel, H. Lemieux, M. Rosca, 2009, Advanced drug delivery reviews.

Carnitine biosynthesis in rat liver slices.

R. A. Cox, C. Hoppel, 1974, Biochimica et biophysica acta.

Effect of starvation on the disposition of free and peptide-linked trimethyllysine in the rat.

C. Hoppel, A. Davis, 1986, The Journal of nutrition.

Carnitine biosynthesis. Hydroxylation of N6-trimethyl-lysine to 3-hydroxy-N6-trimethyl-lysine.

C. Hoppel, D. S. Sachan, 1980, The Biochemical journal.

Butyrobetaine availability in liver is a regulatory factor for carnitine biosynthesis in rat. Flux through butyrobetaine hydroxylase in fasting state.

C. Hoppel, A. Sandor, 1989, European journal of biochemistry.

N6-Trimethyl-lysine metabolism. 3-Hydroxy-N6-trimethyl-lysine and carnitine biosynthesis.

R. A. Cox, C. Hoppel, R. Novak, 1980, The Biochemical journal.

Spiropentaneacetic acid as a specific inhibitor of medium-chain acyl-CoA dehydrogenase.

C. Hoppel, C L Hoppel, K. Tserng, 1991, Biochemistry.

Decreased carnitine biosynthesis in rats with secondary biliary cirrhosis

S. Krähenbühl, C. Hoppel, E. Brass, 2000, Hepatology.

Hypercarnitinemia in cirrhosis

L. Duranti, C. Hoppel, R. Fuller, 1985, Hepatology.

Quantification of acylcarnitines.

C. Hoppel, E. Brass, 1985, Clinical chemistry.

ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects

C. Hoppel, Xiaoyan Sun, X. Qi, 2019, Nature Communications.

Multiple Mitochondrial Alterations in a Case of Myopathy

C. Hoppel, B. Tandler, D. Koontz, 2014, Ultrastructural pathology.

C. Hoppel, J. Kirwan, B. Tandler, 2021, The Journal of biological chemistry.

BAM15‐mediated mitochondrial uncoupling protects against obesity and improves glycemic control

C. Hoppel, K. Hoehn, C. Fealy, 2020, EMBO molecular medicine.

Giant Mitochondria (Megamitochondria)

C. Hoppel, B. Tandler, 2013 .

Deficiency of the reduced nicotinamide adenine dinucleotide dehydrogenase component of complex I of mitochondrial electron transport. Fatal infantile lactic acidosis and hypermetabolism with skeletal-cardiac myopathy and encephalopathy.

D. Kerr, C. Hoppel, U. Roessmann, 1987, The Journal of clinical investigation.

Anesthetic Hypersensitivity in a Case-Controlled Series of Patients With Mitochondrial Disease

C. Hoppel, P. Morgan, M. Sedensky, 2021, Anesthesia and analgesia.

A mutation in mitochondrial complex I increases ethanol sensitivity in Caenorhabditis elegans.

C. Hoppel, E. Kayser, P. Morgan, 2003, Alcoholism, clinical and experimental research.

Relationship between serum carnitine, acylcarnitines, and renal function in patients with chronic renal disease.

C. Hoppel, D. Fouque, J. Kopple, 2006, Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation.

Effect of Maternal Obesity on Placental Lipid Metabolism

P. Glazebrook, C. Hoppel, P. Catalano, 2017, Endocrinology.

Aging decreases electron transport complex III activity in heart interfibrillar mitochondria by alteration of the cytochrome c binding site.

M. Ikeda-Saito, C. Hoppel, C. T. Migita, 2001, Journal of molecular and cellular cardiology.

Mitochondrial dysfunction in cardiac disease: ischemia--reperfusion, aging, and heart failure.

C. Hoppel, B. Tandler, S. Moghaddas, 2001, Journal of molecular and cellular cardiology.

Rapid high-performance liquid chromatography of 3-methylhistidine in human urine.

C. Hoppel, S. Ingalls, P. Minkler, 1987, Journal of chromatography.

Ischemic injury to mitochondrial electron transport in the aging heart: damage to the iron-sulfur protein subunit of electron transport complex III.

M. Ikeda-Saito, C. Hoppel, C. T. Migita, 2001, Archives of biochemistry and biophysics.

Inflammatory Breast Cancer as a Model Disease to Study Tumor Angiogenesis: Results of a Phase IB Trial of Combination SU5416 and Doxorubicin

J. Lewin, J. Duerk, J. Jesberger, 2007, Clinical Cancer Research.

Exercise plasma metabolomics and xenometabolomics in obese, sedentary, insulin-resistant women: impact of a fitness and weight loss intervention.

O. Fiehn, G. Hunter, C. Hoppel, 2019, American journal of physiology. Endocrinology and metabolism.

Anesthesia and bariatric surgery gut preparation alter plasma acylcarnitines reflective of mitochondrial fat and branched-chain amino acid oxidation.

S. Bhattacharyya, C. Hoppel, S. Adams, 2017, American journal of physiology. Endocrinology and metabolism.

Acylcarnitines as markers of exercise‐associated fuel partitioning, xenometabolism, and potential signals to muscle afferent neurons

O. Fiehn, G. Hunter, C. Hoppel, 2017, Experimental physiology.

A phase I trial of radiotherapy and simultaneous 24-hour paclitaxel in patients with locally advanced head and neck squamous cell carcinoma.

C. Hoppel, W. Mackay, A. Mugharbil, 1997, Seminars in oncology.

Plasma concentrations of 5‐(4‐hydroxyphenyl)‐5‐phenylhydantoin in phenytoin‐treated patients

C. Hoppel, A. Rane, F. Sjöqvist, 1977, Clinical pharmacology and therapeutics.

Mass fragmentographic determination of diphenylhydantoin and its main metabolite, 5-(4-hydroxyphenyl)-5-phenylhydantoin, in human plasma.

C. Hoppel, M. Garle, M. Elander, 1976, Journal of chromatography.

Kinetics of placentally transferred phenytoin and its p-hydroxylated metabolites in newborn infants.

C. Hoppel, B. Höjer, A. Rane, 1979, British Journal of Clinical Pharmacology.

Missense mutations in the BCS1L gene as a cause of the Björnstad syndrome.

J. Seidman, R. Eavey, C. Seidman, 2007, The New England journal of medicine.

Subsurface cisterns in mouse hepatocytes

C. Hoppel, B. Tandler, 1974, The Anatomical record.

KINETICS OFPLACENTALLY TRANSFERREDPHENYTOINAND ITS P-HYDROXYLATEDMETABOLITESINNEWBORN INFANTS

C. Hoppel, A. Rane, B. Hojer, 1979 .

Comparison of L-carnitine pharmacokinetics with and without baseline correction following administration of single 20-mg/kg intravenous dose.

C. Hoppel, B. Cabana, C. Sahajwalla, 1995, Journal of pharmaceutical sciences.

Multiple-dose pharmacokinetics and bioequivalence of L-carnitine 330-mg tablet versus 1-g chewable tablet versus enteral solution in healthy adult male volunteers.

C. Hoppel, B. Cabana, C. Sahajwalla, 1995, Journal of pharmaceutical sciences.

Riboflavin and mouse hepatic cell structure and function. Mitochondrial oxidative metabolism in severe deficiency states.

C. Hoppel, B. Tandler, 1975, The Journal of nutrition.

A novel null mutation in the pyruvate dehydrogenase phosphatase catalytic subunit gene (PDP1) causing pyruvate dehydrogenase complex deficiency

D. Kerr, A. Bergin, C. Hoppel, 2019, JIMD reports.

The FASEB Journal • FJ Express Full-Length Article Reversal of mitochondrial defects before ischemia protects the aged heart

C. Hoppel, S. Moghaddas, E. Lesnefsky, 2022 .

Carnitine deficiency associated with ornithine transcarbamylase deficiency.

C. Hoppel, E. Mayatepek, T. Kurczynski, 1991, Pediatric neurology.

Improved high-performance liquid chromatographic method for the determination of 6-N,N,N-trimethyllysine in plasma and urine: biomedical application of chromatographic figures of merit and amine mobile phase modifiers.

C. Hoppel, S. Ingalls, E. Erdos, 1986, Journal of chromatography.

Lipids activate skeletal muscle mitochondrial fission and quality control networks to induce insulin resistance in humans.

B. Burguera, C. Hoppel, D. Hsia, 2021, Metabolism: clinical and experimental.

Impact of a weight loss and fitness intervention on exercise‐associated plasma oxylipin patterns in obese, insulin‐resistant, sedentary women

O. Fiehn, G. Hunter, C. Hoppel, 2020, Physiological reports.

Novel ETF dehydrogenase mutations in a patient with mild glutaric aciduria type II and complex II-III deficiency in liver and muscle

K. Gernert, L. Wolfe, J. Vockley, 2010, Journal of Inherited Metabolic Disease.

Quantitative H2S-mediated protein sulfhydration reveals metabolic reprogramming during the integrated stress response

Charles R. Evans, P. Arvan, M. Parisien, 2015, eLife.

Quantitative assessment of anaplerosis from propionate in pig heart in vivo.

Henri Brunengraber, William C Stanley, C. Hoppel, 2003, American journal of physiology. Endocrinology and metabolism.

Mitochondria in the human heart

C. Hoppel, H. Lemieux, C. L. Hoppel, 2009, Journal of bioenergetics and biomembranes.

Ischemia, rather than reperfusion, inhibits respiration through cytochrome oxidase in the isolated, perfused rabbit heart: role of cardiolipin.

T. Slabe, C. Hoppel, B. Tandler, 2004, American journal of physiology. Heart and circulatory physiology.

Determination of ibuprofen in human plasma by high-performance liquid chromatography.

H. Litowitz, C. Hoppel, L. Olanoff, 1984, Journal of chromatography.

Prolonged exposure to high dietary lipids is not associated with lipotoxicity in heart failure.

M. Chandler, B. Hoit, C. Hoppel, 2009, Journal of molecular and cellular cardiology.

Mitochondrial respiratory chain complex I deficiency with clinical and biochemical features of long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency.

S. Packman, G. Enns, M. Golabi, 2000, The Journal of pediatrics.

Time to harmonize mitochondrial syndrome nomenclature and classification: A consensus from the North American Mitochondrial Disease Consortium (NAMDC).

J. Ganesh, S. Dimauro, F. Scaglia, 2022, Molecular genetics and metabolism.

Dysregulated cellular redox status during hyperammonemia causes mitochondrial dysfunction and senescence by inhibiting sirtuin‐mediated deacetylation

C. Hoppel, S. Dasarathy, B. Willard, 2023, Aging cell.

Peroxisomal and Mitochondrial Oxidation of Fatty Acids in the Heart, Assessed from the 13C Labeling of Malonyl-CoA and the Acetyl Moiety of Citrate*

C. Hoppel, H. Brunengraber, F. David, 2005, Journal of Biological Chemistry.

Lethal neonatal case and review of primary short-chain enoyl-CoA hydratase (SCEH) deficiency associated with secondary lymphocyte pyruvate dehydrogenase complex (PDC) deficiency.

S. Ferdinandusse, R. Wanders, D. Kerr, 2017, Molecular genetics and metabolism.

Parkinson's disease-associated pathogenic VPS35 mutation causes complex I deficits.

Wenzhang Wang, Xiongwei Zhu, C. Hoppel, 2017, Biochimica et biophysica acta. Molecular basis of disease.

Understanding physiologic phospholipid maintenance in the context of brain mitochondrial phospholipid alterations after cardiac arrest.

L. Becker, C. Hoppel, M. Nishikimi, 2021, Mitochondrion.

Quality improvement of mitochondrial respiratory chain complex enzyme assays using Caenorhabditis elegans

C. Hoppel, P. Morgan, M. Sedensky, 2011, Genetics in Medicine.

Enhanced modification of cardiolipin during ischemia in the aged heart.

C. Hoppel, E. Lesnefsky, P. Minkler, 2009, Journal of molecular and cellular cardiology.

Plasma carnitine in alcoholism.

C. Hoppel, R. Fuller, 1988, Alcoholism, clinical and experimental research.

Bioenergetic functions in subpopulations of heart mitochondria are preserved in a non-obese type 2 diabetes rat model (Goto-Kakizaki)

C. Hoppel, F. Loy, R. Isola, 2020, Scientific Reports.

Mitochondrial electron transport and aging in the heart

C. Hoppel, B. Tandler, S. Moghaddas, 2002 .

Mitochondrial Bioenergetics in the Heart

C. Hoppel, B. Tandler, Qun Chen, 2014 .

Defects in skeletal muscle subsarcolemmal mitochondria in a non-obese model of type 2 diabetes mellitus

C. Hoppel, N. Lai, C. Kummitha, 2017, PloS one.

Increased Mitochondrial Oxidative Phosphorylation in the Liver Is Associated With Obesity and Insulin Resistance

Joseph H Nadeau, Paola Solinas, L. Burrage, 2011, Obesity.

Decrease in mitochondrial function in rat cardiac permeabilized fibers correlates with the aging phenotype.

C. Hoppel, Edwin J. Vazquez, H. Fujioka, 2010, The journals of gerontology. Series A, Biological sciences and medical sciences.

Skeletal muscle mitochondrial DNA injury in patients with unilateral peripheral arterial disease.

C. Hoppel, W. Hiatt, H. Bhat, 1999, Circulation.

1143 METABOLIC EFFECTS OF TREATMENT OF SYSTEMIC CARNITINE DEFICIENCY

D. Kerr, S. Shurin, C. Hoppel, 1981, Pediatric Research.

An enzymatic method for the determination of butyrobetaine via conversion to carnitine after isolation by high performance liquid chromatography.

C. Hoppel, S. Ingalls, P. Minkler, 1988, Clinica chimica acta; international journal of clinical chemistry.

Abnormal fatty acid utilization during prolonged fasting in chronic uremia.

C. Hoppel, E. Ricanati, K. Tserng, 1987, Kidney international. Supplement.

Autosomal dominant acute necrotizing encephalopathy

M. Wiznitzer, D. Kerr, M. Warman, 2003, Neurology.

Relationships between expression of BCS1L, mitochondrial bioenergetics, and fatigue among patients with prostate cancer

C. Hoppel, M. Cooney, B. Daly, 2019, Cancer management and research.

Aging defect at the QO site of complex III augments oxyradical production in rat heart interfibrillar mitochondria.

C. Hoppel, Edward J Lesnefsky, S. Moghaddas, 2003, Archives of biochemistry and biophysics.

Hepatic mitochondrial inner-membrane properties, beta-oxidation and carnitine palmitoyltransferases A and B. Effects of genetic obesity and starvation.

C. Hoppel, L. Brady, P. Brady, 1986, Biochemical Journal.

Identification of unusual phospholipids from bovine heart mitochondria by HPLC-MS/MS

C. Hoppel, Junhwan Kim, 2020, Journal of Lipid Research.

Quantification of free carnitine, individual short- and medium-chain acylcarnitines, and total carnitine in plasma by high-performance liquid chromatography.

C. Hoppel, P. Minkler, 1993, Analytical biochemistry.

Combined partial deficiency of muscle carnitine palmitoyltransferase and carnitine with autosomal dominant inheritance.

C. Hoppel, V. Ionasescu, G. Hug, 1980, Journal of neurology, neurosurgery, and psychiatry.

Partial muscle carnitine palmitoyltransferase-A deficiency. Rhabdomyolysis associated with transiently decreased muscle carnitine content after ibuprofen therapy.

C. Hoppel, N. S. Ross, 1987, JAMA.

Quinol type compound in cytochrome c preparations leads to non-enzymatic reduction of cytochrome c during the measurement of complex III activity.

C. Hoppel, S. Moghaddas, E. Lesnefsky, 2007, Mitochondrion.

Comments on quantitation of carnitine esters by high performance liquid chromatography: Reply to E. Schmidt-Sommerfeld and D. Penn

C. Hoppel, S. Ingalls, P. Minkler, 1994 .

Phase II and pharmacokinetic trial of rebeccamycin analog in advanced biliary cancers

A. Chak, C. Hoppel, P. Fu, 2009, Cancer Chemotherapy and Pharmacology.

Is carnitine palmitoyltransferase I (CPT-I) exclusively in the mitochondrial outer membrane?

C. Hoppel, B. Tandler, J. Kerner, 1997 .

Preliminary Clinical and Pharmacologic Investigation of Photodynamic Therapy with the Silicon Phthalocyanine Photosensitizer Pc 4 for Primary or Metastatic Cutaneous Cancers

M. E. Kenney, N. Oleinick, M. Kenney, 2011, Frontiers in Oncology.

A phase I pharmacokinetic and pharmacodynamic study of SU5416 and Adriamycin in inflammatory breast cancer

J. Lewin, C. Connell, J. Jesberger, 2001 .

Urinary acylcarnitines are altered in human kidney cancer

R. Weiss, C. Hoppel, Lining Guo, 2012, International Journal of Cancer.

Long-term L-carnitine treatment in isovaleric acidemia.

C. Hoppel, E. Mayatepek, T. Kurczynski, 1991, Pediatric neurology.

Identification of unusual phospholipids from bovine heart mitochondria by HPLC-MS/MS.

C. Hoppel, Junhwan Kim, 2020, Journal of Lipid Research.

Pc 4 photodynamic therapy of U87 (human glioma) orthotopic tumor in nude rat brain

David Dean, Jiayang Sun, Nancy L. Oleinick, 2005, SPIE BiOS.

Possible Bioenergetic Biomarker for Chronic Cancer-Related Fatigue

C. Hoppel, B. Daly, J. Dorth, 2021, Nursing research.

Association between Mitochondrial Bioenergetics and Radiation- Related Fatigue: A Possible Mechanism and Novel Target

C. Hoppel, B. Daly, C. Hsiao, 2015 .

Aging-dependent changes in rat heart mitochondrial glutaredoxins—Implications for redox regulation☆

C. Hoppel, J. Mieyal, E. Lesnefsky, 2013, Redox biology.

Ultrastructural effects of riboflavin deficiency on rat hepatic mitochondria

C. Hoppel, B. Tandler, 1980, The Anatomical record.

Relationship between hepatic mitochondrial oxidative metabolism and morphology during riboflavin deficiency and recovery in mice.

C. Hoppel, B. Tandler, 1976, Journal of NutriLife.

Atypical urinary opiate excretion pattern.

C. Hoppel, S. Ingalls, C. L. Schilling, 1997, Journal of Analytical Toxicology.

Exercise training and diet-induced weight loss increase markers of hepatic bile acid (BA) synthesis and reduce serum total BA concentrations in obese women.

G. Hunter, C. Hoppel, J. Newman, 2021, American journal of physiology. Endocrinology and metabolism.

N6-Trimethyl-lysine metabolism. Structural identification of the metabolite 3-hydroxy-N6-trimethyl-lysine.

T. J. Swift, C. Hoppel, R. Novak, 1980, Biochemical Journal.

Discovery of a redox-thiol switch regulating cellular energy metabolism

P. Arvan, M. Parisien, R. Kibbey, 2019, bioRxiv.

Functional redundancy of mitochondrial enoyl‐CoA isomerases in the oxidation of unsaturated fatty acids

R. Wanders, C. Hoppel, J. Sass, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Involvement of All-trans-retinal in Acute Light-induced Retinopathy of Mice*

K. Palczewski, C. Hoppel, M. Golczak, 2009, Journal of Biological Chemistry.

Comprehensive approach to the quantitative analysis of mitochondrial phospholipids by HPLC-MS.

C. Hoppel, Junhwan Kim, 2013, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Relationship of primary mitochondrial respiratory chain dysfunction to fiber type abnormalities in skeletal muscle

S. Packman, S. DeArmond, G. Enns, 2005, Clinical genetics.

Kruppel-like factor 4 is critical for transcriptional control of cardiac mitochondrial homeostasis.

J. Stamler, C. Hoppel, Fanghua Ye, 2015, The Journal of clinical investigation.

Reversible Blockade of Electron Transport during Ischemia Protects Mitochondria and Decreases Myocardial Injury following Reperfusion

C. Hoppel, Qun Chen, S. Moghaddas, 2006, Journal of Pharmacology and Experimental Therapeutics.

Pc 4 photodynamic therapy of U87‐derived human glioma in the nude rat

M. E. Kenney, L. Lilge, D. Dean, 2005, Lasers in surgery and medicine.

Altered carnitine metabolism in dialysis patients with reduced physical function may be due to dysfunctional fatty acid oxidation.

C. Hoppel, L. Spry, William J. Murphy, 2012, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Time to harmonize mitochondrial syndrome nomenclature and classification: A consensus from the North American Mitochondrial Disease Consortium (NAMDC).

J. Ganesh, S. Dimauro, John L.P. Thompson, 2022, Molecular genetics and metabolism.

Metabolic response to carnitine in methylmalonic aciduria. An effective strategy for elimination of propionyl groups.

C. Hoppel, D. Millington, C. Roe, 1983, Archives of disease in childhood.

New aspects of impaired mitochondrial function in heart failure

C. Hoppel, M. Rosca, 2009, Journal of bioenergetics and biomembranes.

Investigating the link of ACAD10 deficiency to type 2 diabetes mellitus

Yudong Wang, J. Vockley, C. Hoppel, 2018, Journal of Inherited Metabolic Disease.

The action of digitonin on rat liver mitochondria. The effects on enzyme content.

C. Hoppel, C. Cooper, C. Hoppel, 1968, The Biochemical journal.

Analyzing mitochondrial function in human peripheral blood mononuclear cells.

C. Hoppel, Chao-Pin Hsiao, 2018, Analytical biochemistry.

Mitochondrial Disorders: Metabolic and Genetic Basis

D. Kerr, C. Hoppel, S. Debrosse, 2014 .

Determination of total carnitine in human urine by high-performance liquid chromatography.

C. Hoppel, S. Ingalls, P. Minkler, 1987, Journal of chromatography.

Deficiency oftheReducedNicotinamide AdenineDinucleotide Dehydrogenase ComponentofComplexIofMitochondrial Electron Transport

C. Hoppel, 1987 .

Phase I study of the EGFR tyrosine kinase inhibitor erlotinib in combination with docetaxel and radiation in locally advanced squamous cell cancer of the head and neck (SCCHN).

A. Argiris, C. Hoppel, M. Cooney, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Selective and accurate C5 acylcarnitine quantitation by UHPLC-MS/MS: Distinguishing true isovaleric acidemia from pivalate derived interference.

C. Hoppel, S. Ingalls, P. Minkler, 2017, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

A mutation in mitochondrial complex I increases ethanol sensitivity in Caenorhabditis elegans.

C. Hoppel, P. Morgan, M. Sedensky, 2003, Alcoholism, clinical and experimental research.

Decreased cytochrome c mediates an age-related decline of oxidative phosphorylation in rat kidney mitochondria.

C. Hoppel, H. Fujioka, John F. O'Toole, 2010, The Biochemical journal.

Evidence for compartmentalization of mammalian carotenoid metabolism

C. Hoppel, J. Lintig, Grzegorz Palczewski, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.