S. Anant

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C-->U editing of neurofibromatosis 1 mRNA occurs in tumors that express both the type II transcript and apobec-1, the catalytic subunit of the apolipoprotein B mRNA-editing enzyme.

D. Viskochil, D. Mukhopadhyay, S. Anant, 2002, American journal of human genetics.

Gastrin-mediated interleukin-8 and cyclooxygenase-2 gene expression: differential transcriptional and posttranscriptional mechanisms.

Timothy C Wang, C. Pothoulakis, T. Wang, 2008, Gastroenterology.

Diphenyl difluoroketone: a curcumin derivative with potent in vivo anticancer activity.

K. Hideg, P. Kuppusamy, S. Anant, 2008, Cancer research.

A Bimodal Nanosensor for Probing Influenza Fusion Protein Activity Using Magnetic Relaxation.

J. Zimmerberg, S. Anant, S. Santra, 2021, ACS sensors.

14-3-3σ-Dependent Resistance to Cisplatin

P. Pantazis, S. Anant, C. Houchen, 2009 .

Stromal contributions to the carcinogenic process

S. Anant, Mark C Spaw, S. Thomas, 2017, Molecular carcinogenesis.

Preparation of siRNA-encapsulated PLGA nanoparticles for sustained release of siRNA and evaluation of encapsulation efficiency.

P. Pantazis, S. Anant, C. Houchen, 2012, Methods in molecular biology.

Preclinical Development 3 , 5-Bis ( 2 , 4-Difluorobenzylidene )-4-piperidone , a Novel Compound That Affects Pancreatic Cancer Growth and Angiogenesis

R. Jensen, N. Nicholes, S. Anant, 2011 .

3,5-Bis(2,4-Difluorobenzylidene)-4-piperidone, a Novel Compound That Affects Pancreatic Cancer Growth and Angiogenesis

R. Jensen, N. Nicholes, S. Anant, 2011, Molecular Cancer Therapeutics.

Wnt inhibitory factor 1 induces apoptosis and inhibits cervical cancer growth, invasion and angiogenesis in vivo

A. Reis, S. Lightfoot, S. Anant, 2012, Oncogene.

Nanoparticles in radiation therapy: a summary of various approaches to enhance radiosensitization in cancer

S. Anant, Deep Kwatra, Shrikant Anant, 2013 .

PEGylated murine Granulocyte-macrophage colony-stimulating factor: production, purification, and characterization.

Mei Han, S. Anant, B. Dieckgraefe, 2005, Protein expression and purification.

DNA Methyltransferases: A Novel Target for Prevention and Therapy

S. Anant, D. Subramaniam, R. Thombre, 2013, Front. Oncol..

Crocetinic acid inhibits hedgehog signaling to inhibit pancreatic cancer stem cells

S. Islam, P. Rangarajan, S. Anant, 2015, Oncotarget.

Apobec-1 protects intestine from radiation injury through posttranscriptional regulation of cyclooxygenase-2 expression.

S. Young, D. Mukhopadhyay, S. Anant, 2004, Gastroenterology.

Abstract 3901: RBM3 drives tumor angiogenesis by modulating miR-210.

S. Anant, D. Subramaniam, S. Ramalingam, 2013 .

mRNA Stability Increases myc Untranslated Region of c-′ Apobec-1 to This Motif in the 3 Binding Site for Apobec-1 : Binding of in Apolipoprotein B mRNA Is a High-Affinity ( UUUN [ A / U ] U ) Downstream

S. Anant, N. Davidson, 1999 .

p53 Inactivation Upregulates p73 Expression through E2F-1 Mediated Transcription

T. Sakai, A. Thor, S. Anant, 2012, PloS one.

Open Access Research

P. Pantazis, S. Anant, C. Houchen, 2022 .

Dietary fiber decreases colonic epithelial cell proliferation and protein synthetic rates in human subjects.

S. Anant, M. Rennie, B. Patterson, 2006, American journal of physiology. Endocrinology and metabolism.

A Review of Promising Natural Chemopreventive Agents for Head and Neck Cancer

S. Anant, S. Thomas, R. Aliani, 2018, Cancer Prevention Research.

Honokiol induces cytotoxic and cytostatic effects in malignant melanoma cancer cells.

G. Kaushik, S. Anant, D. Subramaniam, 2012, American journal of surgery.

Activation of apoptosis by 1-hydroxy-5,7-dimethoxy-2-naphthalene-carboxaldehyde, a novel compound from Aegle marmelos.

S. Anant, D. Subramaniam, R. May, 2008, Cancer research.

Aegle marmelos Novel Compound from 1-Hydroxy-5 , 7-Dimethoxy-2-Naphthalene-Carboxaldehyde , a Activation of Apoptosis by Updated

S. Anant, D. Subramaniam, R. May, 2008 .

Cancer Stem Cell Metabolism and Potential Therapeutic Targets

S. Anant, S. Thomas, Levi Arnold, 2018, Front. Oncol..

Dynamic antagonism between RNA-binding protein CUGBP2 and cyclooxygenase-2-mediated prostaglandin E2 in radiation damage.

D. Mukhopadhyay, S. Anant, B. Dieckgraefe, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Integrative Oncology

G. Dobos, S. Anant, C. Witt, 2013, Evidence-based complementary and alternative medicine : eCAM.

Doublecortin-like kinase 1 is a therapeutic target in squamous cell carcinoma

O. Tawfik, S. Anant, J. Ashcraft, 2022, bioRxiv.

Role of Oral Microbiome in Disease Predictions - Current Advances

S. Anant, S. Umar, S. Padhye, 2020, Biomedical Journal of Scientific & Technical Research.

Super-enhancers: novel target for pancreatic ductal adenocarcinoma

S. Anant, D. Subramaniam, P. Dandawate, 2019, Oncotarget.

EF24 suppresses maturation and inflammatory response in dendritic cells.

S. Anant, V. Awasthi, S. Awasthi, 2012, International immunology.

Urine and serum analysis of consumed curcuminoids using an IkappaB-luciferase surrogate marker assay.

P. Pantazis, S. Anant, D. Subramaniam, 2010, In vivo.

EP4 mediates PGE2 dependent cell survival through the PI3 kinase/AKT pathway.

S. Anant, C. Houchen, R. George, 2007, Prostaglandins & other lipid mediators.

Prosurvival and antiapoptotic effects of PGE2 in radiation injury are mediated by EP2 receptor in intestine.

S. Anant, R. Breyer, C. Houchen, 2003, American journal of physiology. Gastrointestinal and liver physiology.

Recent Progress in the Study of Intestinal Apolipoprotein B Gene Expression

S. Anant, N. Davidson, 2001 .

Yin-Yang of Oxidative Stress in Pancreatic Cancers

S. Anant, P. Dandawate, Sonali Choudhury, 2021, Handbook of Oxidative Stress in Cancer: Mechanistic Aspects.

Reg IV regulates normal intestinal and colorectal cancer cell susceptibility to radiation-induced apoptosis.

S. Anant, R. May, B. Dieckgraefe, 2010, Gastroenterology.

Crocetin: an agent derived from saffron for prevention and therapy for cancer.

S. Anant, G. Reed, A. Ray, 2012, Current pharmaceutical biotechnology.

Effect of Black Raspberry Extract in Inhibiting NFκ B Dependent Radioprotection in Human Breast Cancer Cells

S. Anant, V. Awasthi, T. Herman, 2009, Nutrition and cancer.

Suppressing STAT5 signaling affects osteosarcoma growth and stemness

T. Iwakuma, S. Anant, D. Subramaniam, 2020, Cell Death & Disease.

HuR and TTP: two RNA binding proteins that deliver message from the 3' end.

S. Anant, C. Houchen, 2009, Gastroenterology.

Prevention of colitis-associated cancer: natural compounds that target the IL-6 soluble receptor.

S. Anant, Cate M Moriasi, D. Subramaniam, 2012, Anti-cancer agents in medicinal chemistry.

Evidence of functional cross talk between the Notch and NF-κB pathways in nonneoplastic hyperproliferating colonic epithelium.

R. Jensen, S. Anant, S. Umar, 2013, American journal of physiology. Gastrointestinal and liver physiology.

Evidence of functional cross-talk between the Notch and NF-κ B pathways in non-neoplastic 1 hyperproliferating colonic epithelium 2 3 4

R. Jensen, S. Anant, Lijun, 2012 .

Identification and regulation of protein components of the apolipoprotein B mRNA editing enzyme. A complex event.

S. Anant, N. Davidson, 2002, Trends in cardiovascular medicine.

Expression and Polymorphism of Toll-Like Receptor 4 and Effect on NF-κB Mediated Inflammation in Colon Cancer Patients

S. Anant, M. Rouabhia, A. Semlali, 2016, PloS one.

American Journal of Physiology: Gastrointestinal and Liver Physiology American Journal of Physiology: Heart and Circulatory Physi- QlQgY American Journal of Physiology: Regulatory, Integrative and Comparative Physiology American Journal of Physiology: Renal, Fluid and Electrolyte

David M. Pritchard, Michael Camilleri, Gianrico Farrugia, 2003 .

Preclinical Development CDK-4 Inhibitor P 276 Sensitizes Pancreatic Cancer Cells to Gemcitabine-Induced Apoptosis

S. Anant, Somesh D. Sharma, D. Subramaniam, 2012 .

RNA binding protein CUGBP 2 / CELF 2 mediates curcumin-induced mitotic catastrophe of pancreatic cancer cells

R. Postier, R. Jensen, S. Anant, 2015 .

RNA Binding Protein CUGBP2/CELF2 Mediates Curcumin-Induced Mitotic Catastrophe of Pancreatic Cancer Cells

R. Postier, R. Jensen, S. Anant, 2011, PloS one.

Curcumin induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by modulating akt and p38 mAPK

Murugesan V. S. Rajaram, P. Kuppusamy, S. Anant, 2007, Cancer biology & therapy.

Honokiol radiosensitizes colorectal cancer cells: enhanced activity in cells with mismatch repair defects.

R. Postier, S. Anant, D. Subramaniam, 2011, American journal of physiology. Gastrointestinal and liver physiology.

Growth Factors as Treatment Options for Intestinal Inflammation

J. Korzenik, S. Anant, B. Dieckgraefe, 2006, Annals of the New York Academy of Sciences.

Translational Inhibition of Colonic Epithelial Heat Shock Proteins by IFN-γ and TNF-α in Intestinal Inflammation

S. Anant, E. Chang, M. Ciancio, 2007 .

Translational inhibition of colonic epithelial heat shock proteins by IFN-gamma and TNF-alpha in intestinal inflammation.

S. Anant, E. Chang, M. Ciancio, 2007, Gastroenterology.

Tumorigenesis and Neoplastic Progression The RNA-Binding Protein Musashi 1 Affects Medulloblastoma Growth via a Network of Cancer-Related Genes and Is an Indicator of Poor Prognosis

P. Northcott, S. Pfister, C. Vogel, 2012 .

3-Aminobenzamide delays rejoining of DNA strand breaks in gamma-irradiated lymphocytes from patients with breast cancer and not cervical cancer.

S. Mukherji, D. Mukhopadhyay, S. Anant, 1994, Neoplasma.

Thyroid hormone regulates hepatic triglyceride mobilization and apolipoprotein B messenger ribonucleic Acid editing in a murine model of congenital hypothyroidism.

D. Mukhopadhyay, S. Anant, N. Davidson, 2003, Endocrinology.

Biochemical and molecular characterization of two cytidine deaminases in the nematode Caenorhabditis elegans.

S. Anant, N. Davidson, G. Walker, 2002, The Biochemical journal.

Apobec-1 transcription in rat colon cancer: decreased apobec-1 protein production through alterations in polysome distribution and mRNA translation associated with upstream AUGs.

D. Mukhopadhyay, S. Anant, N. Davidson, 2002, Biochimica et biophysica acta.

ARCD-1, an apobec-1-related cytidine deaminase, exerts a dominant negative effect on C to U RNA editing.

D. Mukhopadhyay, S. Anant, S. Kennedy, 2001, American journal of physiology. Cell physiology.

Ô‖Identification of GRY-RBP as an Apolipoprotein B RNA-binding Protein That Interacts with Both Apobec-1 and Apobec-1 Complementation Factor to Modulate C to U Editing*

N. Navaratnam, S. Anant, S. Kennedy, 2001, The Journal of Biological Chemistry.

Reduced Expression of RNA Binding Protein CELF2, a Putative Tumor Suppressor Gene in Colon Cancer.

S. Anant, D. Subramaniam, S. Ramalingam, 2012, Immuno-gastroenterology.

CUGBP2 downregulation by prostaglandin E2 protects colon cancer cells from radiation-induced mitotic catastrophe.

S. Anant, S. Ramalingam, R. May, 2008, American journal of physiology. Gastrointestinal and liver physiology.

Functional antagonism between RNA binding proteins HuR and CUGBP2 determines the fate of COX-2 mRNA translation.

S. Anant, R. May, B. Dieckgraefe, 2007, Gastroenterology.

Role of bacterial infection in the epigenetic regulation of Wnt antagonist WIF1 by PRC2 protein EZH2

S. Anant, V. Jala, B. Haribabu, 2014, Oncogene.

Bitter melon: a panacea for inflammation and cancer.

S. Anant, D. Subramaniam, P. Dandawate, 2016, Chinese journal of natural medicines.

Bitter Melon as a Therapy for Diabetes, Inflammation, and Cancer: a Panacea?

S. Anant, P. Dandawate, S. Padhye, 2016, Current Pharmacology Reports.

Preclinical Pharmacokinetics of Fosciclopirox, a Novel Treatment of Urothelial Cancers, in Rats and Dogs

M. McKenna, R. Jensen, S. Anant, 2019, The Journal of Pharmacology and Experimental Therapeutics.

Identification of GRY-RBP as an apolipoprotein B RNA-binding protein that interacts with both apobec-1 and apobec-1 complementation factor to modulate C to U editing.

N. Navaratnam, J. Scott, S. Anant, 2001, Journal of Biological Chemistry.

Mutant p53 Depletion by Novel Inhibitors for HSP40/J-Domain Proteins Derived from the Natural Compound Plumbagin

T. Iwakuma, A. Parrales, S. Anant, 2022, Cancers.

Synthesis and bioevaluation of new vascular-targeting and anti-angiogenic thieno[2,3-d]pyrimidin-4(3H)-ones.

S. Anant, P. Dandawate, Ion Andronache, 2020, European journal of medicinal chemistry.

Honokiol as a Radiosensitizing Agent for Colorectal Cancers

S. Anant, D. Subramaniam, Zhongtao Zhang, 2013, Current Colorectal Cancer Reports.

Targeting transcription factor TCF4 by γ-Mangostin, a natural xanthone

B. Krishnamachary, S. Anant, D. Subramaniam, 2019, Oncotarget.

CLEFMA-an anti-proliferative curcuminoid from structure-activity relationship studies on 3,5-bis(benzylidene)-4-piperidones.

S. Anant, V. Awasthi, Kaustuv Sahoo, 2010, Bioorganic & medicinal chemistry.

Current Approaches to Diagnosis and Treatment of Ductal Carcinoma In Situ and Future Directions.

O. Tawfik, R. Jensen, S. Anant, 2017, Progress in molecular biology and translational science.

Anticancer and antimetastatic potential of enterolactone: Clinical, preclinical and mechanistic perspectives

S. Anant, S. Kadam, S. Padhye, 2019, European journal of pharmacology.

Therapeutic Effects of Phyllanthus Species: Induction of TNF-α-mediated Apoptosis in HepG2 Hepatocellular Carcinoma Cells

S. Anant, D. Subramaniam, B. Dieckgraefe, 2006 .

Ethnopharmacological Approaches to Wound Repair

S. Anant, F. Afifi, A. Taranalli, 2013, Evidence-based complementary and alternative medicine : eCAM.

Methanolic Extracts of Bitter Melon Inhibit Colon Cancer Stem Cells by Affecting Energy Homeostasis and Autophagy

E. Moran, S. Anant, D. Subramaniam, 2013, Evidence-based complementary and alternative medicine : eCAM.

Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas.

S. Anant, B. Dieckgraefe, C. Houchen, 2006, Gastroenterology.

Expression of the Regenerating Gene Family in Inflammatory Bowel Disease Mucosa: Reg Iα Upregulation, Processing, and Antiapoptotic Activity

S. Anant, B. Dieckgraefe, C. Houchen, 2002, Journal of Investigative Medicine.

Cyclooxygenase-2 Gene Expression

S. Anant, S. Sureban, 2006 .

Targeting cancer stem cells and signaling pathways by phytochemicals: Novel approach for breast cancer therapy.

Roy A Jensen, R. Jensen, S. Anant, 2016, Seminars in cancer biology.

Fosciclopirox suppresses growth of high-grade urothelial cancer by targeting the γ-secretase complex

P. Rangarajan, R. Jensen, S. Anant, 2021, Cell Death & Disease.

Prostaglandin E2 reduces radiation-induced epithelial apoptosis through a mechanism involving AKT activation and bax translocation.

S. Anant, F. Muhale, W. Stenson, 2004, The Journal of clinical investigation.

Doublecortin and CaM Kinase‐like‐1 and Leucine‐Rich‐Repeat‐Containing G‐Protein‐Coupled Receptor Mark Quiescent and Cycling Intestinal Stem Cells, Respectively

S. Lightfoot, S. Anant, R. May, 2009, Stem cells.

Identification of a Novel Putative Gastrointestinal Stem Cell and Adenoma Stem Cell Marker, Doublecortin and CaM Kinase‐Like‐1, Following Radiation Injury and in Adenomatous Polyposis Coli/Multiple Intestinal Neoplasia Mice

Clayton Hunt, C. Hunt, S. Anant, 2008, Stem cells.

Psoriasis upregulated phorbolin-1 shares structural but not functional similarity to the mRNA-editing protein apobec-1.

I. Dunham, N. Tommerup, J. Dumanski, 1999, The Journal of investigative dermatology.

Regulatory Role of Quiescence in the Biological Function of Cancer Stem Cells

S. Anant, T. S. Ramasamy, S. Lee, 2020, Stem Cell Reviews and Reports.

Molecular biology of the small intestine

S. Anant, B. Dieckgraefe, V. Ahuja, 2006, Current opinion in gastroenterology.

Granulocyte macrophage colony‐stimulating factor ameliorates DSS‐induced experimental colitis

M. Colonna, S. Anant, B. Dieckgraefe, 2008, Inflammatory bowel diseases.

Prolactin signaling enhances colon cancer stemness by modulating Notch signaling in a Jak2-STAT3/ERK manner.

O. Tawfik, R. Jensen, S. Anant, 2014, Carcinogenesis.

For Peer Review Prolactin induces Notch signaling in a Jak2-STAT and Jak2- ERK pathways in colon cancer stem and progenitor cells

S. Anant, T. Rajendra, I. Physiology, 2013 .

Role of Prolactin and Its Receptor in Colorectal Cancer

S. Anant, D. Subramaniam, J. Baranda, 2014, Current Colorectal Cancer Reports.

Diphenylbutylpiperidine Antipsychotic Drugs Inhibit Prolactin Receptor Signaling to Reduce Growth of Pancreatic Ductal Adenocarcinoma in Mice.

D. Coppola, O. Tawfik, G. Kaushik, 2019, Gastroenterology.

Specific Expression of Activation-induced Cytidine Deaminase (AID), a Novel Member of the RNA-editing Deaminase Family in Germinal Center B Cells*

T. Honjo, M. Muramatsu, K. Kinoshita, 1999, The Journal of Biological Chemistry.

Molecular regulation, evolutionary, and functional adaptations associated with C to U editing of mammalian apolipoproteinB mRNA.

S. Anant, N. Davidson, V. Blanc, 2003, Progress in nucleic acid research and molecular biology.

Histone Demethylases in Colon Cancer

S. Anant, D. Subramaniam, S. Ramalingam, 2014, Current Colorectal Cancer Reports.

Secretory Autophagy in Cancer-Associated Fibroblasts Promotes Head and Neck Cancer Progression and Offers a Novel Therapeutic Target.

O. Tawfik, S. Anant, W. Ding, 2017, Cancer research.

RNA binding protein RBM3 augments kissing loop formation with lncRNAs to enhance translational control

Linheng Li, T. Iwakuma, O. Tawfik, 2021, bioRxiv.

Manipulating MiRNA Expression: a Novel Approach for Colon Cancer Prevention and Chemotherapy

S. Anant, D. Subramaniam, S. Ramalingam, 2015, Current Pharmacology Reports.

Cancer stem cells: a novel paradigm for cancer prevention and treatment.

S. Anant, D. Subramaniam, S. Ramalingam, 2010, Mini reviews in medicinal chemistry.

Tumor-initiating stem cell shapes its microenvironment into an immunosuppressive barrier and pro-tumorigenic niche

Lucinda E. Maddera, Xi C. He, J. Haug, 2021, Cell reports.

Quinomycin A targets Notch signaling pathway in pancreatic cancer stem cells

Rajashri R. Parab, O. Tawfik, R. Jensen, 2015, Oncotarget.

The Histone Demethylase KDM3A, Increased in Human Pancreatic Tumors, Regulates Expression of DCLK1 in and Promotes Tumorigenesis in Mice.

T. Iwakuma, O. Tawfik, R. Jensen, 2019, Gastroenterology.

RNA binding protein RBM3 increases β‐catenin signaling to increase stem cell characteristics in colorectal cancer cells

D. Dixon, S. Anant, D. Subramaniam, 2016, Molecular carcinogenesis.

Impact of HuR inhibition by the small molecule MS-444 on colorectal cancer cell tumorigenesis

D. Dixon, S. Anant, Ranjan Preet, 2016, Oncotarget.

An ornamental plant targets epigenetic signaling to block cancer stem cell-driven colon carcinogenesis.

D. Dixon, S. Anant, D. Subramaniam, 2016, Carcinogenesis.

Dysregulation of reg gene expression occurs early in gastrointestinal tumorigenesis and regulates anti-apoptotic genes

J. Korzenik, S. Anant, B. Dieckgraefe, 2006, Cancer biology & therapy.

RNA editing: cytidine to uridine conversion in apolipoprotein B mRNA.

N. Navaratnam, J. Scott, S. Anant, 2000, Biochimica et biophysica acta.

Cyclooxygenase-2 and Colon Cancer

D. Mukhopadhyay, S. Anant, J. Jung, 2003 .

Molecular mechanisms of apolipoprotein B mRNA editing

S. Anant, N. Davidson, 2001, Current opinion in lipidology.

apobec-1, the Catalytic Subunit of the Mammalian Apolipoprotein B mRNA Editing Enzyme, Is a Novel RNA-binding Protein (*)

S. Anant, N. Davidson, A. MacGinnitie, 1995, The Journal of Biological Chemistry.

Mutagenesis of apobec-1, the Catalytic Subunit of the Mammalian Apolipoprotein B mRNA Editing Enzyme, Reveals Distinct Domains That Mediate Cytosine Nucleoside Deaminase, RNA Binding, and RNA Editing Activity (*)

S. Anant, N. Davidson, A. MacGinnitie, 1995, The Journal of Biological Chemistry.

Bitter Melon as a Therapy for Diabetes, Inflammation, and Cancer: a Panacea?

S. Anant, P. Dandawate, S. Padhye, 2016, Current Pharmacology Reports.

Helicobacter Pylori's Plasticity Zones Are Novel Transposable Elements

S. Anant, D. Berg, D. Subramaniam, 2009, PloS one.

Natural compounds targeting major cell signaling pathways: a novel paradigm for osteosarcoma therapy

K. Neville, G. Kaushik, S. Anant, 2017, Journal of Hematology & Oncology.

Cucurbitacin B and I inhibits colon cancer growth by targeting the Notch signaling pathway

B. Krishnamachary, G. Kaushik, R. Jensen, 2020, Scientific Reports.

Functional cooperativity of p97 and histone deacetylase 6 in mediating DNA repair in mantle cell lymphoma cells

R. Jensen, S. Anant, D. Subramaniam, 2019, Leukemia.

Curcumin and turmeric attenuate arsenic-induced angiogenesis in ovo.

A. Varman, P. Pantazis, S. Anant, 2010, Alternative therapies in health and medicine.

Curcumin Induces Cell Death in Esophageal Cancer Cells through Modulating Notch Signaling

Prateek Sharma, S. Anant, D. Subramaniam, 2012, PloS one.

Targeting Cancer Stem Cells for Chemoprevention of Pancreatic Cancer.

G. Kaushik, S. Anant, D. Subramaniam, 2017, Current medicinal chemistry.

Differential Effects of β-catenin and NF-κB Interplay in the Regulation of Cell Proliferation, Inflammation and Tumorigenesis in Response to Bacterial Infection

S. Anant, S. Umar, I. Ahmed, 2013, PloS one.

Dietary Interventions Ameliorate Infectious Colitis by Restoring the Microbiome and Promoting Stem Cell Proliferation in Mice

S. Anant, Jason R. Stubbs, T. Attard, 2021, International journal of molecular sciences.

The RNA-binding protein Musashi1 affects medulloblastoma growth via a network of cancer-related genes and is an indicator of poor prognosis.

P. Northcott, S. Pfister, C. Vogel, 2012, The American journal of pathology.

Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism

P. Pantazis, S. Anant, R. May, 2011, Journal of nanobiotechnology.

Characterization of Enantiomeric Bile Acid-induced Apoptosis in Colon Cancer Cell Lines*

S. Anant, D. Covey, Douglas F Covey, 2009, Journal of Biological Chemistry.

Targeting Major Signaling Pathways of Bladder Cancer with Phytochemicals: A Review

S. Anant, D. Subramaniam, John A. Taylor, 2020, Nutrition and cancer.

Loss of p21Waf1/Cip1/Sdi1 enhances intestinal stem cell survival following radiation injury.

S. Anant, R. May, B. Dieckgraefe, 2009, American journal of physiology. Gastrointestinal and liver physiology.

CDK-4 Inhibitor P276 Sensitizes Pancreatic Cancer Cells to Gemcitabine-Induced Apoptosis

S. Anant, Somesh D. Sharma, D. Subramaniam, 2012, Molecular Cancer Therapeutics.

Azoxymethane protects intestinal stem cells and reduces crypt epithelial mitosis through a COX-1-dependent mechanism.

S. Anant, R. May, B. Dieckgraefe, 2006, American journal of physiology. Gastrointestinal and liver physiology.

Translation inhibition during cell cycle arrest and apoptosis: Mcl-1 is a novel target for RNA binding protein CUGBP2.

S. Anant, D. Subramaniam, S. Ramalingam, 2008, American journal of physiology. Gastrointestinal and liver physiology.

Novel intestinal splice variants of RNA-binding protein CUGBP2: isoform-specific effects on mitotic catastrophe.

S. Anant, D. Subramaniam, S. Ramalingam, 2008, American journal of physiology. Gastrointestinal and liver physiology.

Cancer Stem Cells: Novel Target Using Dietary Components for Prevention and Treatment

S. Anant, D. Subramaniam, A. Dhar, 2012 .

Suppressing STAT5 signaling affects osteosarcoma growth and stemness

T. Iwakuma, S. Anant, D. Subramaniam, 2020, Cell Death & Disease.

Translation regulatory factor RBM3 is a proto-oncogene that prevents mitotic catastrophe

R. Postier, D. Brackett, S. Anant, 2008, Oncogene.

Gene Expression Profiling of NF-1-Associated and Sporadic Pilocytic Astrocytoma Identifies Aldehyde Dehydrogenase 1 Family Member L1 (ALDH1L1) as an Underexpressed Candidate Biomarker in Aggressive Subtypes

Y. Asmann, J. Sarkaria, B. Scheithauer, 2008, Journal of neuropathology and experimental neurology.

Honokiol in Combination with Radiation Targets Notch Signaling to Inhibit Colon Cancer Stem Cells

S. Anant, D. Subramaniam, S. Ramalingam, 2012, Molecular Cancer Therapeutics.

Celastrol and Triptolide Suppress Stemness in Triple Negative Breast Cancer: Notch as a Therapeutic Target for Stem Cells

R. Jensen, S. Anant, P. Dandawate, 2021, Biomedicines.

DCAMKL-1 regulates epithelial-mesenchymal transition in human pancreatic cells through a miR-200a-dependent mechanism.

M. Lerner, R. Postier, D. Brackett, 2011, Cancer research.

Bitter melon extracts enhance the activity of chemotherapeutic agents through the modulation of multiple drug resistance.

S. Anant, A. Mitra, A. Dhar, 2013, Journal of pharmaceutical sciences.

Knockdown of musashi-1 results in tumor growth arrest through inhibition of c-myc, notch-1 and emt by let-7a, mir-144 and mir-200a micrornas dependent mechanisms respectively

S. Anant, R. May, C. Houchen, 2011 .

Identification of a novel putative pancreatic stem/progenitor cell marker DCAMKL-1 in normal mouse pancreas.

R. Postier, D. Brackett, C. Rao, 2010, American journal of physiology. Gastrointestinal and liver physiology.

Selective blockade of DCAMKL-1 results in tumor growth arrest by a Let-7a MicroRNA-dependent mechanism.

S. Anant, D. Subramaniam, S. Ramalingam, 2009, Gastroenterology.

Epigenetic Signatures of Breast Cancer Genes

S. Anant, S. Ramalingam, A. Dhar, 2013 .

Histone Demethylases in Cancer

S. Anant, S. Ramalingam, J. Baranda, 2015, Current Pharmacology Reports.

Coupled mRNA stabilization and translational silencing of cyclooxygenase-2 by a novel RNA binding protein, CUGBP2.

D. Mukhopadhyay, S. Anant, S. Kennedy, 2003, Molecular cell.

Prolactin receptor signaling: A novel target for cancer treatment - Exploring anti-PRLR signaling strategies

S. Anant, P. Dandawate, D. Standing, 2023, Frontiers in Endocrinology.

An AU-Rich Sequence Element (UUUN[A/U]U) Downstream of the Edited C in Apolipoprotein B mRNA Is a High-Affinity Binding Site for Apobec-1: Binding of Apobec-1 to This Motif in the 3′ Untranslated Region of c-myc Increases mRNA Stability

Nicholas O. Davidson, S. Anant, N. Davidson, 2000, Molecular and Cellular Biology.

Role of RNA-Binding Proteins in Colorectal Carcinogenesis

S. Anant, S. Ramalingam, C. Houchen, 2010, Current colorectal cancer reports.

Enteric infection coupled with chronic Notch pathway inhibition alters colonic mucus composition leading to dysbiosis, barrier disruption and colitis

S. Owens, S. Anant, S. Umar, 2018, PloS one.

A New Pentafluorothio-Substituted Curcuminoid with Superior Antitumor Activity

D. Kögel, S. Anant, D. Subramaniam, 2021, Biomolecules.

The curcuminoid CLEFMA selectively induces cell death in H441 lung adenocarcinoma cells via oxidative stress

S. Anant, V. Awasthi, M. Dozmorov, 2012, Investigational New Drugs.

Honokiol inhibits melanoma stem cells by targeting notch signaling

G. Kaushik, S. Anant, D. Subramaniam, 2015, Molecular carcinogenesis.

Infection-induced signals generated at the plasma membrane epigenetically regulate Wnt signaling in vitro and in vivo

S. Anant, D. Subramaniam, P. Dandawate, 2019, The Journal of Biological Chemistry.

A cytidine deaminase expressed in the post-infective L3 stage of the filarial nematode, Brugia pahangi, has a novel RNA-binding activity.

S. Anant, N. Davidson, E. Devaney, 1997, Molecular and biochemical parasitology.

Hydrolytic nucleoside and nucleotide deamination, and genetic instability: a possible link between RNA-editing enzymes and cancer?

S. Anant, N. Davidson, 2003, Trends in molecular medicine.

Distinct Compartmentalization of NF-κB Activity in Crypt and Crypt-Denuded Lamina Propria Precedes and Accompanies Hyperplasia and/or Colitis following Bacterial Infection

S. Anant, S. Umar, I. Ahmed, 2011, Infection and Immunity.

Co-localization of autophagy-related protein p62 with cancer stem cell marker dclk1 may hamper dclk1's elimination during colon cancer development and progression

S. Anant, J. Ashcraft, V. Jala, 2019, Oncotarget.

Synthetic adiponectin-receptor agonist, AdipoRon, induces glycolytic dependence in pancreatic cancer cells

S. Anant, R. M. Walsh, M. VanSaun, 2022, Cell Death & Disease.

Knockdown of RNA binding protein musashi-1 leads to tumor regression in vivo.

H. McLeod, S. Anant, S. Ramalingam, 2008, Gastroenterology.

Metastatic Tumor-in-a-Dish, a Novel Multicellular Organoid to Study Lung Colonization and Predict Therapeutic Response.

Scott Weir, G. Sitta Sittampalam, Ossama Tawfik, 2019, Cancer research.

Honokiol affects melanoma cell growth by targeting the AMP-activated protein kinase signaling pathway.

G. Kaushik, R. Jensen, S. Anant, 2014, American journal of surgery.

Abstract 2419: Understanding the role of DCLK1 mediated invadopodia regulation in HNSCC

S. Anant, S. Thomas, Thuc Ly, 2022, Cancer Research.

Development and Characterization of an In Vitro Model for Radiation-Induced Fibrosis

O. Tawfik, B. Kimler, S. Anant, 2018, Radiation Research.

Identification of the putative intestinal stem cell marker doublecortin and CaM kinase‐like‐1 in Barrett's esophagus and esophageal adenocarcinoma

S. Meltzer, S. Lightfoot, S. Anant, 2012, Journal of gastroenterology and hepatology.

Glycemic impact of a diet and lifestyle intervention on diabetics and prediabetics during treatment for non-muscle invasive bladder cancer

S. Anant, J. Holzbeierlein, David C Robbins, 2020, Nutrition and cancer.

Proceedings of the Indo-U.S. bilateral workshop on accelerating botanicals/biologics agent development research for cancer chemoprevention, treatment, and survival

F. Sarkar, E. Hawk, B. Aggarwal, 2013, Cancer medicine.

Halogenated Bis(methoxybenzylidene)‐4‐piperidone Curcuminoids with Improved Anticancer Activity

Florian Schmitt, S. Anant, D. Subramaniam, 2018, ChemMedChem.

Enhanced IFNα Signaling Promotes Ligand-Independent Activation of ERα to Promote Aromatase Inhibitor Resistance in Breast Cancer

S. Anant, J. Lewis-Wambi, P. Dandawate, 2021, Cancers.

Cancer-Associated Fibroblasts Drive Glycolysis in a Targetable Signaling Loop Implicated in Head and Neck Squamous Cell Carcinoma Progression.

B. Van Houten, O. Tawfik, S. Anant, 2018, Cancer research.

Novel Role for RNA-binding Protein CUGBP2 in Mammalian RNA Editing

N. Navaratnam, D. Mukhopadhyay, S. Anant, 2001, The Journal of Biological Chemistry.

Cabozantinib (cabo) combined with durvalumab (durva) in gastroesophageal (GE) cancer and other gastrointestinal (GI) malignancies: Preliminary phase Ib CAMILLA study results.

S. Anant, D. Subramaniam, J. Baranda, 2020 .

The Role of STATs in Ovarian Cancer: Exploring Their Potential for Therapy

S. Anant, S. M. Thomas, D. Standing, 2023, Cancers.

Tumor M2-PK: A novel urine marker of bladder cancer

G. Kaushik, S. Anant, John A. Taylor, 2019, PloS one.

Honokiol Affects Stem Cell Viability by Suppressing Oncogenic YAP1 Function to Inhibit Colon Tumorigenesis

R. Jensen, S. Anant, D. Subramaniam, 2021, Cells.

Reg4‐induced mitogenesis involves Akt‐GSK3β‐β‐Catenin‐TCF‐4 signaling in human colorectal cancer

S. Anant, B. Dieckgraefe, C. Houchen, 2014, Molecular carcinogenesis.

Expression of a novel regenerating gene product, Reg IV, by high density fermentation in Pichia pastoris: production, purification, and characterization.

S. Anant, B. Dieckgraefe, J. Ladenson, 2003, Protein expression and purification.

Toll‐like receptor‐7 ligand imiquimod induces type I interferon and antimicrobial peptides to ameliorate dextran sodium sulfate‐induced acute colitis

S. Anant, B. Dieckgraefe, C. Houchen, 2012, Inflammatory bowel diseases.

Molecular Carcinogenesis

D. Dixon, R. Jensen, S. Anant, 2019 .

Abstract PR05: Effects of Hsp90 inhibitors on triple-negative breast cancer: Notch as a therapeutic target for stem cells

P. Rangarajan, R. Jensen, S. Anant, 2013 .

Histone Demethylases in Cancer

S. Anant, S. Ramalingam, J. Baranda, 2015, Current Pharmacology Reports.

Association of losartan with outcomes in metastatic pancreatic cancer patients treated with chemotherapy

S. Anant, P. Dandawate, A. Kasi, 2021, Journal of clinical and translational research.

Manipulating MiRNA Expression: a Novel Approach for Colon Cancer Prevention and Chemotherapy

S. Anant, D. Subramaniam, S. Ramalingam, 2015, Current Pharmacology Reports.

Utility of a bacterial infection model to study epithelial–mesenchymal transition, mesenchymal–epithelial transition or tumorigenesis

O. Tawfik, S. Anant, C. Houchen, 2014, Oncogene.

CUGBP2 Plays a Critical Role in Apoptosis of Breast Cancer Cells in Response to Genotoxic Injury

D. Mukhopadhyay, S. Anant, B. Dieckgraefe, 2003, Annals of the New York Academy of Sciences.

An alternatively spliced form of apobec-1 messenger RNA is overexpressed in human colon cancer.

S. Anant, N. Davidson, D. Baunoch, 1998, Gastroenterology.

Evolutionary Origins of the Mammalian ApolipoproteinB RNA Editing Enzyme, Apobec-1: Structural Homology Inferred from Analysis of a Cloned Chicken Small Intestinal Cytidine Deaminase

S. Anant, N. Davidson, Hongri Yu, 1998, Biological chemistry.

Immunoglobin A Deficiency and Squamous Cell Carcinoma With a Rare Presentation as Anal Cancer

R. Madan, S. Anant, N. Gupta, 2022, Journal of Medical Cases.

Apolipoprotein B messenger RNA editing: insights into the molecular regulation of post-transcriptional cytidine deamination

S. Anant, N. Davidson, A. MacGinnitie, 1995, Current opinion in lipidology.

Familial adenomatous polyposis in pediatrics: natural history, emerging surveillance and management protocols, chemopreventive strategies, and areas of ongoing debate

S. Anant, T. Attard, S. Septer, 2016, Familial Cancer.

Pharmacokinetics of ciclopirox prodrug, a novel agent for the treatment of bladder cancer, in animals and humans.

H. Burris, R. Jensen, S. Anant, 2019, Journal of Clinical Oncology.

Preclinical development of ciclopirox prodrug for the treatment of non-muscle invasive and muscle invasive bladder cancer.

M. McKenna, R. Jensen, S. Anant, 2018 .

Safety, dose tolerance, pharmacokinetics and pharmacodynamics study of CPX-POM in patients with advanced solid tumors.

M. McKenna, H. Burris, R. Jensen, 2018 .

Preclinical Development Honokiol in Combination with Radiation Targets Notch Signaling to Inhibit Colon Cancer Stem Cells

S. Anant, D. Subramaniam, S. Ramalingam, 2012 .

Anticancer Activity of Novel Difluorinated Curcumin Analog and Its Inclusion Complex with 2-Hydroxypropyl-β-Cyclodextrin against Pancreatic Cancer

S. Anant, P. Dandawate, S. Padhye, 2023, International journal of molecular sciences.

DCLK1 isoforms and aberrant Notch signaling in the regulation of human and murine colitis

S. Anant, Jason R. Stubbs, D. Welch, 2021, Cell death discovery.

Cucurbitacin B and I inhibits colon cancer growth by targeting the Notch signaling pathway

B. Krishnamachary, G. Kaushik, R. Jensen, 2020, Scientific Reports.

DCAMKL-1 regulates epithelial-mesenchymal transition in human pancreatic cells through a miR-200a-dependent mechanism.

M. Lerner, R. Postier, D. Brackett, 2011, Cancer research.

Loss of p21Waf1/Cip1/Sdi1 enhances intestinal stem cell survival following radiation injury.

S. Anant, R. May, B. Dieckgraefe, 2009, American journal of physiology. Gastrointestinal and liver physiology.

Evidence of functional cross talk between the Notch and NF-κB pathways in nonneoplastic hyperproliferating colonic epithelium.

R. Jensen, S. Anant, S. Umar, 2013, American journal of physiology. Gastrointestinal and liver physiology.

Helicobacter Pylori' S Plasticity Zones Are Novel Transposable Elements Recommended Citation Helicobacter Pylori's Plasticity Zones Are Novel Transposable Elements

S. Anant, D. Subramaniam, O. Barabas, 2022 .

IRAK1 is a critical mediator of low molecular weight hyaluronic acid-induced stemness in high-grade serous ovarian cancer

S. Anant, K. Roby, P. Dandawate, 2023, bioRxiv.

ACTIVATION OF APOPTOSIS BY 1-HYDROXY-5, 7-DIMETHOXY-2-NAPHTHALENE-CARBOXALDEHYDE (HDNC), A NOVEL COMPOUND FROM AEGLE MARMELOS

S. Anant, D. Subramaniam, R. May, 2009 .

Critical Roles of Notch and Wnt/β-Catenin Pathways in the Regulation of Hyperplasia and/or Colitis in Response to Bacterial Infection

O. Tawfik, S. Anant, S. Umar, 2012, Infection and Immunity.

Expression of the Regenerating Gene Family in Inflammatory Bowel Disease Mucosa: Reg Iα Upregulation, Processing, and Antiapoptotic Activity

S. Anant, B. Dieckgraefe, C. Houchen, 2002, Journal of Investigative Medicine.

CUGBP2 downregulation by prostaglandin E2 protects colon cancer cells from radiation-induced mitotic catastrophe.

S. Anant, S. Ramalingam, R. May, 2008, American journal of physiology. Gastrointestinal and liver physiology.

The binding of apobec-1 to mammalian apo B RNA is stabilized by the presence of complementation factors which are required for post-transcriptional editing.

S. Anant, N. Davidson, A. MacGinnitie, 1995, Nucleic acids symposium series.