X. Roca

发表

Extensive in silico analysis of NF1 splicing defects uncovers determinants for splicing outcome upon 5′ splice‐site disruption

A. Krainer, T. Callens, L. Messiaen, 2007, Human mutation.

Comprehensive splice-site analysis using comparative genomics

R. Sachidanandam, A. Krainer, M. L. Hastings, 2006, Nucleic acids research.

Pick one, but be quick: 5' splice sites and the problems of too many choices.

A. Krainer, I. Eperon, X. Roca, 2013, Genes & development.

Features of 5'-splice-site efficiency derived from disease-causing mutations and comparative genomics.

Vessela N Kristensen, Andrew J. Olson, Ravi Sachidanandam, 2007, Genome research.

Intrinsic differences between authentic and cryptic 5' splice sites.

Ravi Sachidanandam, Adrian R Krainer, R. Sachidanandam, 2003, Nucleic acids research.

Characterization of the Regulation of CD46 RNA Alternative Splicing*

X. Roca, Eling Goh, Sze Jing Tang, 2016, The Journal of Biological Chemistry.

Alternative splicing analysis in human monocytes and macrophages reveals MBNL1 as major regulator

X. Roca, Jie Zheng, Fan Zhang, 2018, Nucleic acids research.

Identification of cis-Acting Elements and Splicing Factors Involved in the Regulation of BIM Pre-mRNA Splicing

X. Roca, W. Juan, S. Ong, 2014, PloS one.

Alternative polyadenylation expands the mRNA isoform repertoire of human CD46.

X. Roca, Sze Jing Tang, P. T. Ly, 2017, Gene.

Pan-cancer pervasive upregulation of 3′ UTR splicing drives tumourigenesis

Yvonne Tay, M. Fullwood, Yufen Goh, 2022, Nature Cell Biology.

Widespread recognition of 5' splice sites by noncanonical base-pairing to U1 snRNA involving bulged nucleotides.

A. Krainer, X. Roca, C. Bennett, 2012, Genes & development.

KRAINER splice sites ′ Determinants of the inherent strength of human 5

R. Sachidanandam, A. Krainer, X. Roca, 2005 .

Human PRPF40B regulates hundreds of alternative splicing targets and represses a hypoxia expression signature

X. Roca, Jie Zheng, Fan Zhang, 2019, RNA.

The lupus autoantigen La/Ssb is an Xist-binding protein involved in Xist folding and cloud formation

Lingyi Chen, X. Roca, Li-Feng Zhang, 2020, Nucleic acids research.

ZAP isoforms regulate unfolded protein response and epithelial- mesenchymal transition

X. Roca, D. Luo, P. T. Ly, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Noncanonical registers and base pairs in human 5′ splice-site selection

X. Roca, Shufang Luo, Jia Xin Jessie Ho, 2016, Nucleic acids research.

Informational Suppression to Probe RNA:RNA Interactions in the Context of Ribonucleoproteins: U1 and 5' Splice-Site Base-Pairing.

X. Roca, Jiazi Tan, Xavier Roca, 2016, Methods in molecular biology.

A novel 3' splice-site mutation and a novel gross deletion in leukocyte adhesion deficiency (LAD)-1.

X. Roca, O. Zach, S. K. Law, 2011, Biochemical and biophysical research communications.

SRRM2 organizes splicing condensates to regulate alternative splicing

X. Roca, Shaohai Xu, Hoi-Yeung Li, 2022, bioRxiv.

A splicing component adapted to gene silencing

A. Krainer, X. Roca, 2009, Nature Biotechnology.

The lupus autoantigen La is an Xist-binding protein involved in Xist folding and cloud formation

Lingyi Chen, X. Roca, Li-Feng Zhang, 2020, bioRxiv.

RNA biology in a test tube—an overview of in vitro systems/assays

Fedor V. Karginov, X. Roca, Xavier Roca, 2012, Wiley interdisciplinary reviews. RNA.

Short/branched-chain acyl-CoA dehydrogenase deficiency due to an IVS3+3A>G mutation that causes exon skipping

R. Sachidanandam, A. Krainer, R. Wanders, 2006, Human Genetics.

METTL4 catalyzes m6Am methylation in U2 snRNA to regulate pre-mRNA splicing

X. Roca, W. S. Goh, Casslynn W. Q. Koh, 2020, bioRxiv.

Viable Mice with Extensive Gene Humanization (25-kbp) Created Using Embryonic Stem Cell/Blastocyst and CRISPR/Zygote Injection Approaches

X. Roca, D. Bergstrom, W. Juan, 2018, Scientific Reports.

Knock-In of a 25-Kilobase Pair BAC-Derived Donor Molecule by Traditional and CRISPR/Cas9-Stimulated Homologous Recombination

X. Roca, D. Bergstrom, W. Juan, 2016, bioRxiv.

Multisite and bidirectional exonic splicing enhancer in CD44 alternative exon v3.

A. Ariza, M. Isamat, X. Roca, 2007, RNA.

Title Antisense oligonucleotide-induced alternative splicing ofthe APOB mRNA generates a novel isoform of APOB

A. Krainer, S. Chew, B. Khoo, 2017 .

BMC Molecular Biology BioMed Central Research article Serum repressing efflux pump CDR1 in Candida albicans

A. Krainer, S. Chew, B. Khoo, 2006 .

A mutation in a rare type of intron in a sodium‐channel gene results in aberrant splicing and causes myotonia

A. Krainer, S. Sakoda, I. Nishino, 2011, Human mutation.

Recognition of atypical 5' splice sites by shifted base-pairing to U1 snRNA

Adrian R Krainer, A. Krainer, X. Roca, 2008, Nature Structural &Molecular Biology.

Determinants of the inherent strength of human 5' splice sites.

Ravi Sachidanandam, Adrian R Krainer, R. Sachidanandam, 2005, RNA.

Overcoming imatinib resistance conferred by the BIM deletion polymorphism in chronic myeloid leukemia with splice-switching antisense oligonucleotides

Jun Liu, F. Rigo, X. Roca, 2017, Oncotarget.

Chromatin loop anchors predict transcript and exon usage

M. Fullwood, C. Kwoh, X. Roca, 2021, Briefings Bioinform..

Histone Deacetylase 3 Inhibition Overcomes BIM Deletion Polymorphism–Mediated Osimertinib Resistance in EGFR-Mutant Lung Cancer

X. Roca, S. Yano, K. Fukuda, 2016, Clinical Cancer Research.

SRSF1 mediates cytokine-induced impaired imatinib sensitivity in chronic myeloid leukemia

A. Krainer, C. Chuah, S. Rozen, 2020, Leukemia.

RNA Secondary Structure-Based Design of Antisense Peptide Nucleic Acids for Modulating Disease-Associated Aberrant Tau Pre-mRNA Alternative Splicing

R. Kierzek, X. Roca, J. Décout, 2019, Molecules.

A Disease-Causing Intronic Point Mutation C19G Alters Tau Exon 10 Splicing via RNA Secondary Structure Rearrangement.

R. Kierzek, X. Roca, Lixia Yang, 2019, Biochemistry.

BCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells

Hyungwon Choi, V. G. Krishnan, X. Roca, 2020, Cell Death & Disease.

Vitamin D modulates human macrophage response to Mycobacterium tuberculosis DNA.

X. Roca, J. Cervantes, A. Chhabra, 2019, Tuberculosis.

Identification of novel splice variants of the human CD44 gene.

M. Isamat, X. Roca, E. Vela, 2006, Biochemical and biophysical research communications.