C. Brancolini

发表

Apoptotic phenotype induced by overexpression of wild-type gas3/PMP22: its relation to the demyelinating peripheral neuropathy CMT1A.

C. Schneider, E. Fabbretti, P. Edomi, 1995, Genes & development.

Impairment of PMP22 transgenic Schwann cells differentiation in culture: implications for Charcot-Marie-Tooth type 1A disease

G. Mancardi, A. Schenone, L. Nobbio, 2004, Neurobiology of Disease.

Guidelines for the use and interpretation of assays for monitoring autophagy

Robert Clarke, Hong Jiang, Hiroyuki Ishida, 2012 .

Guidelines for the use and interpretation of assays formonitoring autophagy (3rd edition)

Sangeeta Khare, Xin Qi, Ying Wang, 2016 .

PP2A regulates HDAC4 nuclear import.

C. Brancolini, Laura Orsatti, P. Gallinari, 2007, Molecular biology of the cell.

Caspase-dependent regulation of histone deacetylase 4 nuclear-cytoplasmic shuttling promotes apoptosis.

G. Del Sal, C. Schneider, C. Brancolini, 2004, Molecular biology of the cell.

Inhibitors of the Ubiquitin-Proteasome System and the cell death machinery: How many pathways are activated?

C. Brancolini, 2008, Current molecular pharmacology.

Different class IIa HDACs repressive complexes regulate specific epigenetic responses related to cell survival in leiomyosarcoma cells

E. Dalla, C. Brancolini, Eros Di Giorgio, 2019, Nucleic acids research.

Sensitivity of human multiple myelomas and myeloid leukemias to the proteasome inhibitor I

D. Delia, C. Brancolini, D. Soligo, 2005, Leukemia.

Quis Custodiet Ipsos Custodes (Who Controls the Controllers)? Two Decades of Studies on HDAC9

C. Brancolini, L. Formisano, T. Gagliano, 2021, Life.

Functions of the growth arrest specific 1 gene in the development of the mouse embryo.

C. Schneider, C. Brancolini, M. Tang, 2001, Developmental biology.

Gas6 anti-apoptotic signaling requires NF-kappa B activation.

R. Verardo, C. Schneider, C. Brancolini, 2001, The Journal of biological chemistry.

Caspase activation and apoptosis in response to proteasome inhibitors

R. Maestro, C. Brancolini, G. Paroni, 2005, Cell Death and Differentiation.

Beside the MEF2 axis: unconventional functions of HDAC4.

C. Brancolini, F. Demarchi, A. Clocchiatti, 2013, Cellular signalling.

Caspase-2-induced Apoptosis Is Dependent on Caspase-9, but Its Processing during UV- or Tumor Necrosis Factor-dependent Cell Death Requires Caspase-3*

C. Schneider, C. Brancolini, G. Paroni, 2001, The Journal of Biological Chemistry.

Isopeptidases in anticancer therapy: looking for inhibitors.

C. Brancolini, A. Sgorbissa, Harish Potu, 2010, American journal of translational research.

Targeting histone deacetylases for combination therapies in neuroendocrine tumors

C. Brancolini, T. Gagliano, 2020, Cancer Gene Therapy.

The Growing Biological Scenario of Growth Arrest

M. E. Ruaro, S. Gustincich, C. Schneider, 1993 .

The death substrate Gas2 binds m‐calpain and increases susceptibility to p53‐dependent apoptosis

C. Schneider, G. Sal, C. Brancolini, 2001, The EMBO journal.

Microfilament reorganization during apoptosis: the role of Gas2, a possible substrate for ICE‐like proteases.

C. Schneider, C. Brancolini, M. Benedetti, 1995, The EMBO journal.

Proteotoxic Stress and Cell Death in Cancer Cells

L. Iuliano, C. Brancolini, 2020, Cancers.

The DeISGylase USP18 limits TRAIL-induced apoptosis through the regulation of TRAIL levels

C. Brancolini, Ivana Manini, A. Sgorbissa, 2013, Cancer biology & therapy.

Proteolytic processing of the adherens junctions components β-catenin and γ-catenin/plakoglobin during apoptosis

C. Schneider, C. Brancolini, A. Sgorbissa, 1998, Cell Death and Differentiation.

The isopeptidase inhibitor 2cPE triggers proteotoxic stress and ATM activation in chronic lymphocytic leukemia cells

D. Delia, C. Brancolini, E. Bianchi, 2016, Oncotarget.

The isopeptidase inhibitor 2 cPE triggers proteotoxic stress and ATM activation in chronic lymphocytic leukemia cells

D. Delia, C. Brancolini, E. Bianchi, 2022 .

Identification of new compounds that trigger apoptosome-independent caspase activation and apoptosis.

C. Brancolini, C. Henderson, E. Aleo, 2006, Cancer research.

Proteolytic processing of the adherens junctions components beta-catenin and gamma-catenin/plakoglobin during apoptosis.

C. Schneider, C. Brancolini, A. Sgorbissa, 1998, Cell death and differentiation.

Gas2, a growth arrest-specific protein, is a component of the microfilament network system

C. Schneider, C. Brancolini, S. Bottega, 1992, The Journal of cell biology.

p optotic phenotype induced y overexpressmn of wdd-type gas 3 / PMP 22 : its relation to the demyelinating peripheral neuropatliy CMT 1 A

E. Fabbretti, P. Edomi, C. Brancolini, 2007 .

Susceptibility to p53 dependent apoptosis correlates with increased levels of Gas2 and Gas3 proteins

C. Schneider, C. Brancolini, S. Marzinotto, 1997, Cell Death and Differentiation.

Homeostatic Mechanisms Governing the Go Phase as Defined by the gas Genes

E. Ruaro, C. Schneider, S. Goruppi, 1996 .

Tissue transglutaminase is a caspase substrate during apoptosis. Cleavage causes loss of transamidating function and is a biochemical marker of caspase 3 activation

A. Scaloni, C. Brancolini, A. Amoresano, 1999, Cell Death and Differentiation.

Caspase-3 and caspase-7 but not caspase-6 cleave Gas2 in vitro: implications for microfilament reorganization during apoptosis.

C. Schneider, C. Brancolini, R. Benetti, 1999, Journal of cell science.

Identification of a gene signature for the prediction of recurrence and progression in non-muscle-invasive bladder cancer

E. Dalla, C. Brancolini, G. Novara, 2022, Molecular Biomedicine.

Caspase-2 Can Trigger Cytochrome c Release and Apoptosis from the Nucleus*

C. Schneider, C. Brancolini, G. Paroni, 2002, The Journal of Biological Chemistry.

Inhibitors of the ubiquitin-proteasome system are not all alike: Identification of a new necrotic pathway

C. Brancolini, F. Demarchi, Carmela Foti, 2009, Autophagy.

Dissection of c-myc domains involved in S phase induction of NIH3T3 fibroblasts.

S. Gustincich, C. Schneider, S. Goruppi, 1994, Oncogene.

Expression of growth arrest-specific (Gas) genes in murine keratinocytes: Gas2 is specifically regulated.

K. H. Richter, F. Marks, C. Brancolini, 1996, Experimental cell research.

GSK3β is a key regulator of the ROS-dependent necrotic death induced by the quinone DMNQ

I. Mavelli, L. Iuliano, C. Brancolini, 2020, Cell Death & Disease.

Change in the expression of a nuclear matrix-associated protein is correlated with cellular transformation.

C. Schneider, C. Brancolini, 1991, Proceedings of the National Academy of Sciences of the United States of America.

The Neuronal Microtubule‐Associated Protein Tau Is a Substrate for Caspase‐3 and an Effector of Apoptosis

G. Ugolini, A. Cattaneo, V. Verzillo, 2000 .

Enhancing Proteotoxic Stress in Leiomyosarcoma Cells Triggers Mitochondrial Dysfunctions, Cell Death, and Antitumor Activity in vivo

E. Dalla, L. Iuliano, C. Brancolini, 2021, Molecular Cancer Therapeutics.

Novel synthesis of 1,2-diaza-1,3-dienes with potential biological activity from cinnamic acids and diazonium salts of anilines

C. Brancolini, M. Scocchi, F. Berti, 2022, RSC advances.

The Isopeptidase Inhibitor G5 Triggers a Caspase-independent Necrotic Death in Cells Resistant to Apoptosis

E. Crivellato, R. Maestro, C. Brancolini, 2009, Journal of Biological Chemistry.

HDACs and the epigenetic plasticity of cancer cells: Target the complexity.

C. Brancolini, T. Gagliano, Martina Minisini, 2022, Pharmacology & therapeutics.

Unscheduled HDAC4 repressive activity in human fibroblasts triggers TP53‐dependent senescence and favors cell transformation

C. Brancolini, Harikrishnareddy Paluvai, Eros Di Giorgio, 2018, Molecular oncology.

Characterization of caspase-dependent and caspase-independent deaths in glioblastoma cells treated with inhibitors of the ubiquitin-proteasome system

S. Gustincich, P. Roncaglia, C. Brancolini, 2009, Molecular Cancer Therapeutics.

MEF2 Is a Converging Hub for Histone Deacetylase 4 and Phosphatidylinositol 3-Kinase/Akt-Induced Transformation

A. D. Dei Tos, R. Maestro, S. Piccinin, 2013, Molecular and Cellular Biology.

HDAC4 in cancer: A multitasking platform to drive not only epigenetic modifications

C. Brancolini, Emma Cuttini, Camilla Goi, 2023, Frontiers in Molecular Biosciences.

HDAC4 degradation during senescence unleashes an epigenetic program driven by AP-1/p300 at selected enhancers and super-enhancers

E. Dalla, C. Brancolini, V. Moresi, 2021, Genome Biology.

The Histone Code of Senescence

C. Brancolini, Harikrishnareddy Paluvai, Eros Di Giorgio, 2020, Cells.

Proteotoxic stress-induced apoptosis in cancer cells: understanding the susceptibility and enhancing the potency

E. Dalla, L. Iuliano, C. Brancolini, 2022, Cell Death Discovery.

HDACs and the epigenetic plasticity of cancer cells: Target the complexity.

C. Brancolini, T. Gagliano, Martina Minisini, 2022, Pharmacology & therapeutics.

gas2 is a multifunctional gene involved in the regulation of apoptosis and chondrogenesis in the developing mouse limb.

C. Schneider, C. Brancolini, D. Yew, 1999, Developmental biology.

Transcriptomic Analysis Unveils Correlations between Regulative Apoptotic Caspases and Genes of Cholesterol Homeostasis in Human Brain

F. Fogolari, C. Brancolini, Raffaella Picco, 2014, PloS one.

Transcriptomic and genomic studies classify NKL54 as a histone deacetylase inhibitor with indirect influence on MEF2-dependent transcription

E. Dalla, A. Mai, C. Weichenberger, 2022, Nucleic acids research.

Dismantling Cell–Cell Contacts during Apoptosis Is Coupled to a Caspase-dependent Proteolytic Cleavage of β-Catenin

Joe Rodriguez, C. Schneider, C. Brancolini, 1997, The Journal of cell biology.

Role of Caspases, Bid, and p53 in the Apoptotic Response Triggered by Histone Deacetylase Inhibitors Trichostatin-A (TSA) and Suberoylanilide Hydroxamic Acid (SAHA)*

R. Maestro, C. Schneider, C. Brancolini, 2003, The Journal of Biological Chemistry.

Twist is substrate for caspase cleavage and proteasome-mediated degradation

R. Maestro, S. Piccinin, S. Demontis, 2006, Cell Death and Differentiation.

Genetic Programs Driving Oncogenic Transformation: Lessons from In Vitro Models

C. Brancolini, Claudio Brancolini, Eros Di Giorgio, 2019, International journal of molecular sciences.

The Calpain System Is Involved in the Constitutive Regulation of β-Catenin Signaling Functions*

S. Dell’Orso, C. Schneider, C. Brancolini, 2005, Journal of Biological Chemistry.

Gas6 Anti-apoptotic Signaling Requires NF-κB Activation*

R. Verardo, C. Schneider, C. Brancolini, 2001, The Journal of Biological Chemistry.

HDAC4 controls senescence and aging by safeguarding the epigenetic identity and ensuring the genomic integrity

E. Dalla, C. Brancolini, V. Moresi, 2020, bioRxiv.

Epigenetic Mechanisms beyond Tumour–Stroma Crosstalk

C. Brancolini, T. Gagliano, 2021, Cancers.

Altering protein turnover in tumor cells: new opportunities for anti-cancer therapies.

C. Brancolini, F. Demarchi, 2005, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

Dephosphorylation and Caspase Processing Generate Distinct Nuclear Pools of Histone Deacetylase 4

D. Fasino, Xiang-Jiao Yang, C. Brancolini, 2007, Molecular and Cellular Biology.

Review Article Isopeptidases in anticancer therapy: looking for inhibitors

C. Brancolini, A. Sgorbissa, H. Potu, 2010 .

The protein encoded by a growth arrest-specific gene (gas6) is a new member of the vitamin K-dependent proteins related to protein S, a negative coregulator in the blood coagulation cascade

C. Schneider, C. Brancolini, G. Manfioletti, 1993, Molecular and cellular biology.

The MEF2–HDAC axis controls proliferation of mammary epithelial cells and acini formation in vitro

C. Brancolini, C. Streuli, A. Clocchiatti, 2015, Journal of Cell Science.

Selective class IIa HDAC inhibitors: myth or reality

C. Brancolini, Eros Di Giorgio, Enrico Gagliostro, 2014, Cellular and Molecular Life Sciences.

Regulation of class IIa HDAC activities: it is not only matter of subcellular localization.

C. Brancolini, Eros Di Giorgio, 2016, Epigenomics.

Apoptotic pathways activated by histone deacetylase inhibitors: implications for the drug-resistant phenotype.

C. Brancolini, C. Henderson, Clare J Henderson, 2003, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

The Transcriptional Repressor hDaxx Potentiates p53-dependent Apoptosis*

G. Del Sal, C. Schneider, M. Gostissa, 2004, Journal of Biological Chemistry.

Class IIa HDACs: from important roles in differentiation to possible implications in tumourigenesis

C. Brancolini, A. Clocchiatti, Cristina Florean, 2011, Journal of cellular and molecular medicine.

CAPNS1 Regulates USP1 Stability and Maintenance of Genome Integrity

C. Schneider, M. Myers, C. Brancolini, 2013, Molecular and Cellular Biology.

Selective class IIa HDAC inhibitors: myth or reality

C. Brancolini, Eros Di Giorgio, Eros Di Giorgio, 2014, Cellular and Molecular Life Sciences.

The co-existence of transcriptional activator and transcriptional repressor MEF2 complexes influences tumor aggressiveness

A. D. Dei Tos, R. Maestro, S. Rossi, 2017, PLoS genetics.

cDNA characterization and chromosome mapping of the human GAS2 gene.

M. Buzzai, C. Schneider, C. Brancolini, 1998, Genomics.

Type I IFNs signaling and apoptosis resistance in glioblastoma cells

C. Brancolini, Ivana Manini, A. Sgorbissa, 2011, Apoptosis.

IFNs, ISGylation and cancer: Cui prodest?

C. Brancolini, A. Sgorbissa, 2012, Cytokine & growth factor reviews.

Cytoplasmic HDAC4 regulates the membrane repair mechanism in Duchenne muscular dystrophy

A. Mai, C. Brancolini, C. Giampietri, 2022, Journal of cachexia, sarcopenia and muscle.

USP18 is a key regulator of the interferon-driven gene network modulating pancreatic beta cell inflammation and apoptosis

P. Marchetti, I. Santin, C. Brancolini, 2012, Cell Death and Disease.

Identification of USP18 as an important regulator of the susceptibility to IFN-alpha and drug-induced apoptosis.

C. Brancolini, A. Sgorbissa, H. Potu, 2010, Cancer research.

Glycan-independent Role of Calnexin in the Intracellular Retention of Charcot-Marie-Tooth 1A Gas3/PMP22 Mutants*

E. Snapp, C. Brancolini, M. Ferrarini, 2005, Journal of Biological Chemistry.

Potent and Selective Non‐hydroxamate Histone Deacetylase 8 Inhibitors

C. Brancolini, F. Meyer‐Almes, C. Meyners, 2016, ChemMedChem.

Phosphorylation of the growth arrest-specific protein Gas2 is coupled to actin rearrangements during Go-->G1 transition in NIH 3T3 cells

C. Schneider, C. Brancolini, Claudio Brancolini, 1994, The Journal of cell biology.

Exposure at the cell surface is required for gas3/PMP22 To regulate both cell death and cell spreading: implication for the Charcot-Marie-Tooth type 1A and Dejerine-Sottas diseases.

C. Schneider, P. Edomi, C. Brancolini, 2000, Molecular biology of the cell.

Rho-dependent regulation of cell spreading by the tetraspan membrane protein Gas3/PMP22.

C. Fiorentini, C. Schneider, E. Agostoni, 1999, Molecular biology of the cell.

Calpain is required for macroautophagy in mammalian cells

C. Schneider, C. Brancolini, C. Bertoli, 2006, The Journal of cell biology.

MEF2 and the tumorigenic process, hic sunt leones.

C. Brancolini, W. Hancock, Eros Di Giorgio, 2018, Biochimica et biophysica acta. Reviews on cancer.

Class IIa HDACs repressive activities on MEF2‐depedent transcription are associated with poor prognosis of ER+ breast tumors

C. Tripodo, C. Brancolini, F. Meyer‐Almes, 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The Control Operated by the Cell Cycle Machinery on MEF2 Stability Contributes to the Downregulation of CDKN1A and Entry into S Phase

C. Brancolini, A. Clocchiatti, Eros Di Giorgio, 2015, Molecular and Cellular Biology.

Tau Cleavage and Dephosphorylation in Cerebellar Granule Neurons Undergoing Apoptosis

C. Barbato, M. Ciotti, A. Cattaneo, 1998, The Journal of Neuroscience.

A regulative epigenetic circuit supervised by HDAC7 represses IGFBP6 and IGFBP7 expression to sustain mammary stemness.

E. Dalla, C. Brancolini, Martina Minisini, 2021, Epigenomics.

Transformation by different oncogenes relies on specific metabolic adaptations

I. Mavelli, C. Brancolini, P. Peruzzo, 2016, Cell cycle.

A Receptor-interacting Protein 1 (RIP1)-independent Necrotic Death under the Control of Protein Phosphatase PP2A That Involves the Reorganization of Actin Cytoskeleton and the Action of Cofilin-1*

C. Brancolini, A. Blangy, Andrea Tomasella, 2014, The Journal of Biological Chemistry.

A Biological Circuit Involving Mef2c, Mef2d, and Hdac9 Controls the Immunosuppressive Functions of CD4+Foxp3+ T-Regulatory Cells

C. Brancolini, U. Beier, Y. Xiong, 2021, Frontiers in Immunology.