A. De Flora

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P2X7-mediated Increased Intracellular Calcium Causes Functional Derangement in Schwann Cells from Rats with CMT1A Neuropathy*

A. Schenone, L. Nobbio, L. Sturla, 2009, The Journal of Biological Chemistry.

Glucose 6-phosphate dehydrogenase activity in membranes of erythrocytes from normal individuals and subjects with Mediterranean G6PD deficiency.

A. De Flora, A. Morelli, M. Frascio, 1978, Biochemical and biophysical research communications.

Mechanisms of perturbation of erythrocyte calcium homeostasis in favism.

G. Damonte, A. De Flora, E. Carafoli, 1992, Cell calcium.

Self‐aggregation of purified and membrane‐bound erythrocyte CD38 induces extensive decrease of its ADP‐ribosyl cyclase activity

E. Zocchi, A. De Flora, L. Calder, 1995, FEBS letters.

Structural role of disulfide bridges in the cyclic ADP‐ribose related bifunctional ectoenzyme CD38

E. Zocchi, A. De Flora, L. Guida, 1995, FEBS letters.

Identification of a high affinity binding site for abscisic acid on human lanthionine synthetase component C-like protein 2.

P. Fossa, E. Cichero, L. Sturla, 2018, The international journal of biochemistry & cell biology.

Heterodimer-loaded erythrocytes as bioreactors for slow delivery of the antiviral drug azidothymidine and the antimycobacterial drug ethambutol.

A. De Flora, M. Magnani, E. Millo, 1999, AIDS research and human retroviruses.

Paracrine Roles of NAD+ and Cyclic ADP-ribose in Increasing Intracellular Calcium and Enhancing Cell Proliferation of 3T3 Fibroblasts*

C. Usai, E. Zocchi, A. De Flora, 2001, The Journal of Biological Chemistry.

In vitro effects of N-acetylcysteine on the mutagenicity of direct-acting compounds and procarcinogens.

S. De Flora, A. De Flora, A. Morelli, 1984, Carcinogenesis.

In vivo effects of N-acetylcysteine on glutathione metabolism and on the biotransformation of carcinogenic and/or mutagenic compounds.

S. De Flora, A. De Flora, A. Morelli, 1985, Carcinogenesis.

A Self-restricted CD38-connexin 43 Cross-talk Affects NAD+ and Cyclic ADP-ribose Metabolism and Regulates Intracellular Calcium in 3T3 Fibroblasts*

C. Usai, E. Zocchi, A. De Flora, 2001, The Journal of Biological Chemistry.

Structural and enzymatic characterization of human recombinant GDP‐D‐mannose‐4,6‐dehydratase

L. Sturla, A. De Flora, M. Tonetti, 1999, FEBS letters.

The metabolism of 6-deoxyhexoses in bacterial and animal cells.

L. Sturla, A. De Flora, M. Tonetti, 1998, Biochimie.

Expression, purification and characterization of GDP‐d‐mannose 4,6‐dehydratase from Escherichia coli

L. Sturla, A. De Flora, M. Tonetti, 1997, FEBS letters.

Binding of abscisic acid to human LANCL2.

L. Sturla, E. Zocchi, A. De Flora, 2011, Biochemical and biophysical research communications.

A single protein immunologically identified as CD38 displays NAD+ glycohydrolase, ADP-ribosyl cyclase and cyclic ADP-ribose hydrolase activities at the outer surface of human erythrocytes.

F. Malavasi, E. Zocchi, A. De Flora, 1993, Biochemical and biophysical research communications.

Role of CD38 in Adipose Tissue: Tuning Coenzyme Availability?

L. Sturla, E. Zocchi, A. De Flora, 2021, Nutrients.

CD38 downregulation modulates NAD+ and NADP(H) levels in thermogenic adipose tissues.

H. Mittrücker, L. Sturla, E. Zocchi, 2020, Biochimica et biophysica acta. Molecular and cell biology of lipids.

Abscisic acid enhances glucose disposal and induces brown fat activity in adipocytes in vitro and in vivo.

L. Sturla, E. Zocchi, A. De Flora, 2017, Biochimica et biophysica acta. Molecular and cell biology of lipids.

NAD+ Levels Control Ca2+ Store Replenishment and Mitogen-induced Increase of Cytosolic Ca2+ by Cyclic ADP-ribose-dependent TRPM2 Channel Gating in Human T Lymphocytes*

L. Sturla, E. Zocchi, A. De Flora, 2012, The Journal of Biological Chemistry.

Mitochondrial Dysfunction Induced by a Cytotoxic Adenine Dinucleotide Produced by ADP-ribosyl Cyclases from cADPR*

Giovanna Basile, E. Zocchi, A. De Flora, 2007, Journal of Biological Chemistry.

Differential Role of NADP+ and NADPH in the Activity and Structure of GDP-D-mannose 4,6-Dehydratase from Two Chlorella Viruses*

J. V. Van Etten, L. Sturla, A. De Flora, 2008, Journal of Biological Chemistry.

Human erythrocyte glucose 6-phosphate dehydrogenase. Content of bound coenzyme.

A. De Flora, A. Morelli, F. Giuliano, 1974, Biochemical and biophysical research communications.

Concentrative Influx of Functionally Active Cyclic ADP-ribose in Dimethyl Sulfoxide-differentiated HL-60 Cells*

L. Sturla, C. Usai, Giovanna Basile, 2004, Journal of Biological Chemistry.

Microgram amounts of abscisic acid in fruit extracts improve glucose tolerance and reduce insulinemia in rats and in humans

E. Zocchi, A. De Flora, P. Ameri, 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The production of activated oxygen species by an interaction of methemoglobin with ascorbate.

A. De Flora, A. Morelli, U. Benatti, 1983, Biochemical and biophysical research communications.

Abscisic Acid Is an Endogenous Stimulator of Insulin Release from Human Pancreatic Islets with Cyclic ADP Ribose as Second Messenger*

C. Usai, I. Moreschi, E. Zocchi, 2008, Journal of Biological Chemistry.

The Plant Hormone Abscisic Acid Stimulates the Proliferation of Human Hemopoietic Progenitors through the Second Messenger Cyclic ADP‐Ribose

G. Damonte, L. Sturla, C. Usai, 2009, Stem cells.

Paramecium bursaria Chlorella Virus 1 Encodes Two Enzymes Involved in the Biosynthesis of GDP-L-fucose and GDP-D-rhamnose*

J. V. Van Etten, G. Damonte, A. Armirotti, 2003, Journal of Biological Chemistry.

Free ADP-ribose in human erythrocytes: pathways of intra-erythrocytic conversion and non-enzymic binding to membrane proteins.

E. Zocchi, A. De Flora, U. Benatti, 1993, The Biochemical journal.

Regulation of human mesenchymal stem cell functions by an autocrine loop involving NAD+ release and P2Y11-mediated signaling.

S. Scaglione, R. Quarto, E. Jacchetti, 2011, Stem cells and development.

Cyclic ADP‐Ribose‐Mediated Expansion and Stimulation of Human Mesenchymal Stem Cells by the Plant Hormone Abscisic Acid

C. Usai, E. Zocchi, A. De Flora, 2008, Stem cells.

Identification of proteolytic activities in the cytosolic compartment of mature human erythrocytes.

A. De Flora, A. Morelli, E. Melloni, 1980, European journal of biochemistry.

Favism: a hemolytic disease associated with increased superoxide dismutase and decreased glutathione peroxidase activities in red blood cells.

I. Mavelli, G. Rotilio, M. Ciriolo, 1984, European journal of biochemistry.

NAADP+ is an agonist of the human P2Y11 purinergic receptor.

C. Usai, I. Moreschi, E. Zocchi, 2008, Cell calcium.

Extracellular NAD+ Is an Agonist of the Human P2Y11 Purinergic Receptor in Human Granulocytes*

L. Sturla, C. Usai, I. Moreschi, 2006, Journal of Biological Chemistry.

Subunit structure and physical properties of an NADP (H) ‐binding protein from human erythrocytes

A. De Flora, A. Morelli, N. G. Wrigley, 1977, FEBS letters.

Emerging Functions of Extracellular Pyridine Nucleotides

E. Zocchi, A. De Flora, S. Bruzzone, 2006, Molecular medicine.

Multiple small molecular weight guanine nucleotide-binding proteins in human erythrocyte membranes.

G. Damonte, E. Zocchi, A. De Flora, 1990, Biochemical and biophysical research communications.

Synthesis and targeted delivery of an azidothymidine homodinucleotide conferring protection to macrophages against retroviral infection.

G. Damonte, A. De Flora, M. Magnani, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Heterogeneity of guanine nucleotide binding proteins in human red blood cell membranes.

G. Damonte, A. De Flora, U. Benatti, 1991, Advances in experimental medicine and biology.

"In situ" characterization of guanine nucleotide-binding properties of erythrocyte membranes.

G. Damonte, A. De Flora, A. Morelli, 1989, Biochemical and biophysical research communications.

Modulation of erythrocyte Ca2+-ATPase by selective calpain cleavage of the calmodulin-binding domain.

T. Vorherr, P. James, J. T. Penniston, 1989, The Journal of biological chemistry.

Extracellular cyclic ADP-ribose potentiates ACh-induced contraction in bovine tracheal smooth muscle.

V. Brusasco, C. Usai, E. Zocchi, 2001, American journal of physiology. Lung cellular and molecular physiology.

Extracellular NAD+ regulates intracellular calcium levels and induces activation of human granulocytes.

C. Usai, I. Moreschi, E. Zocchi, 2006, The Biochemical journal.

Human erythrocyte glucose 6-phosphate dehydrogenase. Physical properties.

R. Cancedda, A. De Flora, A. Bonsignore, 1971, Biochemical and biophysical research communications.

The transmembrane glycoprotein CD38 is a catalytically active transporter responsible for generation and influx of the second messenger cyclic ADP‐ribose across membranes

C. Usai, E. Zocchi, A. De Flora, 1998, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Extracellular cyclic ADP‐ribose increases intracellular free calcium concentration and stimulates proliferation of human hemopoietic progenitors

D. Scadden, C. Usai, E. Zocchi, 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

A methemoglobin-dependent and plasma-stimulated experimental model of oxidative hemolysis.

A. De Flora, A. Morelli, U. Benatti, 1982, Biochemical and biophysical research communications.

Comparative patterns of ‘in vitro’ oxidative hemolysis of normal and glucose 6‐phosphate dehydrogenase (G6PD)‐deficient erythrocytes

A. De Flora, A. Morelli, E. Melloni, 1981, FEBS letters.

Cyclic ADP‐ribose is a second messenger in the lipopolysaccharide‐stimulated activation of murine N9 microglial cell line

C. Usai, I. Moreschi, E. Zocchi, 2006, Journal of neurochemistry.

Interactions of carboplatin with human erythrocytes and murine erythroleukemic cells.

A. De Flora, M. Tonetti, U. Benatti, 1992, Advances in experimental medicine and biology.

Abscisic Acid Stimulates Glucagon-Like Peptide-1 Secretion from L-Cells and Its Oral Administration Increases Plasma Glucagon-Like Peptide-1 Levels in Rats

L. Sturla, E. Zocchi, A. De Flora, 2015, PloS one.

Adenosine diphosphate ribulose in human erythrocytes: a new metabolite with membrane binding properties.

E. Zocchi, A. De Flora, U. Benatti, 1993, Biochemical and biophysical research communications.

Expression of CD38 Increases Intracellular Calcium Concentration and Reduces Doubling Time in HeLa and 3T3 Cells*

C. Usai, E. Zocchi, A. De Flora, 1998, The Journal of Biological Chemistry.

Molecular mechanism and functional role of brefeldin A-mediated ADP-ribosylation of CtBP1/BARS

M. Nardini, C. Cericola, A. Luini, 2013, Proceedings of the National Academy of Sciences.

CD73 Protein as a Source of Extracellular Precursors for Sustained NAD+ Biosynthesis in FK866-treated Tumor Cells*

L. Sturla, A. De Flora, S. Bruzzone, 2013, The Journal of Biological Chemistry.

Effects of the murine L929 and L1210 cell lines on nitric oxide and TNF-alpha production by RAW 264.7 murine macrophages.

L. Sturla, A. De Flora, M. Tonetti, 1997, Biochemical and biophysical research communications.

T-cell suppression mediated by mesenchymal stem cells is deficient in patients with severe aplastic anemia.

E. Zocchi, A. De Flora, F. Frassoni, 2005, Experimental hematology.

Effect of divalent cations on the structure of human erythrocyte glucose 6-P dehydrogenase.

R. Cancedda, A. De Flora, A. Bonsignore, 1971, Biochemical and biophysical research communications.

Distinctive patterns of NADP binding to dimeric and tetrameric glucose 6-phosphate dehydrogenase from human red cells.

R. Cancedda, A. De Flora, A. Bonsignore, 1970, Biochemical and biophysical research communications.

Topology of CD38.

C. Usai, E. Zocchi, A. De Flora, 2000, Chemical immunology.

Identification and characterization of an active soluble form of human CD38 in normal and pathological fluids.

F. Malavasi, A. De Flora, A. Horenstein, 1996, International immunology.

Hormonal effects on structure and catalytic properties of fructose 1,6-bisphosphatase.

A. De Flora, B. Horecker, E. Melloni, 1975, Proceedings of the National Academy of Sciences of the United States of America.

A novel dimeric fluoropyrimidine molecule behaves as a remote precursor of 5-fluoro-2'-deoxyuridine in human erythrocytes.

G. Damonte, A. De Flora, M. Tonetti, 1994, Biochemical pharmacology.

Copper(II) complexes encapsulated in human red blood cells.

E. Rizzarelli, A. De Flora, M. Tonetti, 1995, Journal of inorganic biochemistry.

Enhanced formation of reactive species from cis-diammine-(1,1-cyclobutanedicarboxylato)-platinum(II) (carboplatin) in the presence of oxygen free radicals.

A. De Flora, M. Tonetti, U. Benatti, 1993, Biochemical pharmacology.

In vitro correction of erythrocyte glucose 6-phosphate dehydrogenase (G6PD) deficiency.

A. De Flora, A. Morelli, E. Melloni, 1979, Archives of biochemistry and biophysics.

Rapid purification of glucose 6-phosphate dehydrogenase from human erythrocytes by means of affinity chromatography.

A. De Flora, A. Morelli, F. Giuliano, 1973, The Italian journal of biochemistry.

Enhanced antitumor activity of adriamycin by encapsulation in mouse erythrocytes targeted to liver and lungs.

E. Zocchi, A. De Flora, M. Tonetti, 1989, Pharmacological research.

Conversion of encapsulated 5-fluoro-2'-deoxyuridine 5'-monophosphate to the antineoplastic drug 5-fluoro-2'-deoxyuridine in human erythrocytes.

E. Zocchi, A. De Flora, U. Benatti, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Monoclonal antibodies to human erythrocyte glucose 6‐phosphate dehydrogenase

E. Zocchi, A. De Flora, A. Morelli, 1980, FEBS letters.

Presence and turnover of adenosine diphosphate ribose in human erythrocytes.

E. Zocchi, A. De Flora, U. Benatti, 1992, Biochemical and biophysical research communications.

Role of Liver CD38 in the Regulation of Metabolic Pathways during Cold-Induced Thermogenesis in Mice

H. Mittrücker, L. Sturla, A. De Flora, 2022, Cells.

Autocrine abscisic acid plays a key role in quartz‐induced macrophage activation

G. Damonte, E. Jacchetti, L. Sturla, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Production and hydrolysis of cyclic ADP-ribose at the outer surface of human erythrocytes.

E. Zocchi, A. De Flora, Hon Cheung Lee, 1993, Biochemical and biophysical research communications.

Differences and similarities among three acidic endopeptidases associated with human erythrocyte membranes. Molecular and functional studies.

A. De Flora, A. Morelli, E. Melloni, 1980, Biochimica et biophysica acta.

Favism: impairment of proteolytic systems in red blood cells.

E. Zocchi, A. De Flora, A. Morelli, 1988, Blood.

Prominent role of DT-diaphorase as a cellular mechanism reducing chromium(VI) and reverting its mutagenicity.

S. De Flora, A. De Flora, A. Morelli, 1985, Cancer research.

Impairment of the calcium pump of human erythrocytes by divicine.

A. De Flora, U. Benatti, L. Guida, 1985, Archives of biochemistry and biophysics.

The role of plasma in oxidative haemolysis.

A. De Flora, U. Benatti, L. Guida, 1986, Free radical research communications.

Favism: disordered erythrocyte calcium homeostasis.

A. De Flora, U. Benatti, L. Guida, 1985, Blood.

Insulin-independent stimulation of skeletal muscle glucose uptake by low-dose abscisic acid via AMPK activation

L. Sturla, E. Zocchi, A. De Flora, 2020, Scientific Reports.

G-protein coupling and nuclear translocation of the human abscisic acid receptor LANCL2

L. Sturla, C. Usai, E. Zocchi, 2016, Scientific Reports.

Abscisic Acid Transport in Human Erythrocytes*

E. Zocchi, A. De Flora, E. Turco, 2015, The Journal of Biological Chemistry.

LANCL2 Is Necessary for Abscisic Acid Binding and Signaling in Human Granulocytes and in Rat Insulinoma Cells*

Emanuela Jacchetti, Enrico Millo, Cesare Usai, 2009, The Journal of Biological Chemistry.

Abscisic Acid Released by Human Monocytes Activates Monocytes and Vascular Smooth Muscle Cell Responses Involved in Atherogenesis*

G. Damonte, L. Sturla, C. Usai, 2009, The Journal of Biological Chemistry.

Abscisic acid is an endogenous cytokine in human granulocytes with cyclic ADP-ribose as second messenger

Annalisa Salis, Gianluca Damonte, Enrico Millo, 2007, Proceedings of the National Academy of Sciences.

Metabolism of human erythrocyte glucose-6-phosphate dehydrogenase. VI. Interconversion of multiple molecular forms.

R. Cancedda, A. De Flora, A. Bonsignore, 1971, Archives of biochemistry and biophysics.

Crystalline D-gluconate 6-phosphate dehydrogenase.

A. De Flora, A. Bonsignore, B. Horecker, 1961, The Journal of biological chemistry.

Evidence for the selective release of lysosomal proteinases in fasted rabbits.

A. De Flora, B. Horecker, O. Tsolas, 1976, Biochimie.

Transformation of neutral to alkaline fructose 1,6-bisphosphatase. Converting enzyme activity in the large-particle fraction from rabbit liver.

A. De Flora, B. Horecker, E. Melloni, 1974, Archives of biochemistry and biophysics.

Conversion of neutral to alkaline liver fructose 1,6-bisphosphatase: changes in molecular properties of the enzyme.

A. De Flora, B. Horecker, E. Melloni, 1973, Proceedings of the National Academy of Sciences of the United States of America.

Pharmacokinetic properties of doxorubicin encapsulated in glutaraldehyde-treated canine erythrocytes.

A. De Flora, M. Tonetti, U. Benatti, 1991, American journal of veterinary research.

Encapsulation of doxorubicin in liver-targeted erythrocytes increases the therapeutic index of the drug in a murine metastatic model.

E. Zocchi, A. De Flora, M. Tonetti, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Macrophage protection against human immunodeficiency virus or herpes simplex virus by red blood cell-mediated delivery of a heterodinucleotide of azidothymidine and acyclovir.

G. Damonte, A. De Flora, M. Magnani, 1998, AIDS research and human retroviruses.

Fluridone as a new anti-inflammatory drug.

S. Cuzzocrea, L. Sturla, E. Zocchi, 2013, European Journal of Pharmacology.

Decay of a specific NADP(H)‐binding protein during aging of normal and glucose 6‐phosphate dehydrogenase‐deficient erythrocytes

A. De Flora, A. Morelli, M. Frascio, 1977, FEBS letters.

Pathophysiology of hemolysis in glucose-6-phosphate dehydrogenase deficiency.

P. Arese, A. De Flora, 1990, Seminars in hematology.

Contributions of superoxide, hydrogen peroxide, and transition metal ions to auto-oxidation of the favism-inducing pyrimidine aglycone, divicine, and its reactions with haemoglobin.

A. De Flora, C. Winterbourn, U. Benatti, 1986, Biochemical pharmacology.

ADP-ribosyl cyclases generate two unusual adenine homodinucleotides with cytotoxic activity on mammalian cells.

G. Damonte, A. Armirotti, C. Usai, 2005, Proceedings of the National Academy of Sciences of the United States of America.

CD38 and ADP-ribosyl Cyclase Catalyze the Synthesis of a Dimeric ADP-ribose That Potentiates the Calcium-mobilizing Activity of Cyclic ADP-ribose*

G. Damonte, E. Zocchi, A. De Flora, 1997, The Journal of Biological Chemistry.

Role of macrophage protection in the development of murine AIDS.

A. De Flora, M. Magnani, G. Schiavano, 1999, Journal of acquired immune deficiency syndromes.

Inhibition of murine AIDS by a new azidothymidine homodinucleotide.

A. De Flora, M. Magnani, E. Millo, 1998, Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association.

Isolation and partial characterization of three acidic proteinases in erythrocyte membranes.

A. De Flora, A. Morelli, E. Melloni, 1979, The Biochemical journal.

The interaction of divicine with glutathione and pyridine nucleotides.

A. De Flora, U. Benatti, L. Guida, 1984, Biochemical and biophysical research communications.

Dimeric and tetrameric forms of catalytically active transmembrane CD38 in transfected HeLa cells

E. Zocchi, A. De Flora, S. Bruzzone, 1998, FEBS letters.

NAD+‐dependent internalization of the transmembrane glycoprotein CD38 in human Namalwa B cells

C. Tacchetti, E. Zocchi, A. De Flora, 1996, FEBS letters.

Biochemical mechanisms of glucose-6-phosphate dehydrogenase deficiency.

A. De Flora, A. Morelli, G. Gaetani, 1978, Proceedings of the National Academy of Sciences of the United States of America.

Concentrative Uptake of Cyclic ADP-ribose Generated by BST-1+ Stroma Stimulates Proliferation of Human Hematopoietic Progenitors*

C. Usai, F. Benvenuto, E. Zocchi, 2005, Journal of Biological Chemistry.

The CD38/cyclic ADP-ribose system: a topological paradox.

E. Zocchi, A. De Flora, L. Guida, 1997, The international journal of biochemistry & cell biology.

Paracrine ADP Ribosyl Cyclase-Mediated Regulation of Biological Processes

L. Sturla, A. De Flora, S. Bruzzone, 2022, Cells.

Ligand‐induced internalization of CD38 results in intracellular Ca2+ mobilization: role of NAD+ transport across cell membranes

C. Usai, E. Zocchi, A. De Flora, 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Self-aggregation of the transmembrane glycoprotein CD38 purified from human erythrocytes.

E. Zocchi, A. De Flora, L. Calder, 1994, Biochemical and biophysical research communications.

Abscisic Acid Activates the Murine Microglial Cell Line N9 through the Second Messenger Cyclic ADP-ribose*

Annalisa Salis, Chiara Ferraris, Luisa Franco, 2009, Journal of Biological Chemistry.

Ectocellular in vitro and in vivo metabolism of cADP-ribose in cerebellum.

E. Fedele, G. Fontana, M. Raiteri, 1996, The Biochemical journal.

Evidence of a role for cyclic ADP‐ribose in calcium signalling and neurotransmitter release in cultured astrocytes

E. Fedele, E. Zocchi, A. De Flora, 2001, Journal of neurochemistry.

A new hepatic protein inactivating glucose 6-phosphate dehydrogenase.

A. De Flora, A. Bonsignore, S. Alemà, 1968, The Biochemical journal.

Decay of proteinase and peptidase activities of human and rabbit erythrocytes during cellular aging.

A. De Flora, A. Morelli, E. Melloni, 1981, Biochimica et biophysica acta.

Membrane lipid components of normal and glucose-6-phosphate dehydrogenase-deficient erythrocytes of asymptomatic and favic subjects.

A. De Flora, A. Morelli, E. Melloni, 1981, Acta biologica et medica Germanica.

Radioimmunoassay and chemical properties of glucose 6-phosphate dehydrogenase and of a specific NADP(H)-binding protein (FX) from human erythrocytes.

M. Galliano, A. De Flora, A. Morelli, 1977, Biochimica et biophysica acta.

Encapsulation of adriamycin in human erythrocytes.

E. Zocchi, A. De Flora, U. Benatti, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Stroma‐generated cyclic ADP‐ribose stimulates the expansion of early human hemopoietic progenitors by a paracrine interaction

C. Usai, E. Zocchi, A. De Flora, 2001 .

Paracrinally stimulated expansion of early human hemopoietic progenitors by stroma-generated cyclic ADP-ribose.

C. Usai, E. Zocchi, A. De Flora, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Cyclic ADP‐ribose generation by CD38 improves human hemopoietic stem cell engraftment into NOD/SCID mice

E. Zocchi, A. De Flora, S. Bruzzone, 2003, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Oxidative inactivation of the calcium-stimulated neutral proteinase from human red blood cells by divicine and intracellular protection by reduced glutathione.

A. De Flora, A. Morelli, M. Grasso, 1986, Archives of biochemistry and biophysics.

Calcium-induced alterations in the levels and subcellular distribution of proteolytic enzymes in human red blood cells.

A. De Flora, A. Morelli, M. Grasso, 1986, Biochemical and biophysical research communications.

Human erythrocyte glucose 6-phosphate dehydrogenase: electron microscope studies on structure and interconversion of tetramers, dimers and monomers.

A. De Flora, N. G. Wrigley, A. Bonsignore, 1972, Journal of molecular biology.

Metabolic reduction of chromium by alveolar macrophages and its relationships to cigarette smoke.

S. De Flora, A. De Flora, M. Romano, 1986, The Journal of clinical investigation.

CD38-Induced Metabolic Dysfunction Primes Multiple Myeloma Cells for NAD+-Lowering Agents

A. Neri, A. De Flora, S. Bruzzone, 2023, Antioxidants.

Functional characterization of a synthetic abscisic acid analog with anti-inflammatory activity on human granulocytes and monocytes.

G. Damonte, L. Sturla, E. Zocchi, 2011, Biochemical and biophysical research communications.

Cooperative interactions between native and modified subunits of rabbit liver fructose 1,6-bisphosphatase.

A. De Flora, B. Horecker, E. Melloni, 1974, Archives of Biochemistry and Biophysics.

Cyclic GMP-dependent and -independent Effects on the Synthesis of the Calcium Messengers Cyclic ADP-ribose and Nicotinic Acid Adenine Dinucleotide Phosphate*

A. De Flora, R. Graeff, Hon Cheung Lee, 1998, The Journal of Biological Chemistry.

Selection and characterization of single stranded DNA aptamers for the hormone abscisic Acid.

L. Sturla, E. Zocchi, A. De Flora, 2013, Nucleic acid therapeutics.

Diadenosine Homodinucleotide Products of ADP-ribosyl Cyclases Behave as Modulators of the Purinergic Receptor P2X7*

F. Di Virgilio, E. Jacchetti, A. Schenone, 2010, The Journal of Biological Chemistry.

Glutamate‐mediated overexpression of CD38 in astrocytes cultured with neurones

E. Fedele, E. Zocchi, A. De Flora, 2004, Journal of neurochemistry.

Equilibrative and Concentrative Nucleoside Transporters Mediate Influx of Extracellular Cyclic ADP-Ribose into 3T3 Murine Fibroblasts*

L. Sturla, E. Zocchi, A. De Flora, 2002, The Journal of Biological Chemistry.

Electrophoretic behaviour of human erythrocyte glucose 6-phosphate dehydrogenase during purification.

A. De Flora, A. Bonsignore, D. Dina, 1968, Biochemical and biophysical research communications.

The plant hormone abscisic acid increases in human plasma after hyperglycemia and stimulates glucose consumption by adipocytes and myoblasts

Annalisa Salis, Gianluca Damonte, Davide Maggi, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Hexose monophosphate shunt-stimulated reduction of methemoglobin by divicine.

A. De Flora, M. Tonetti, C. Winterbourn, 1985, Archives of biochemistry and biophysics.

The Diadenosine Homodinucleotide P18 Improves In Vitro Myelination in Experimental Charcot‐Marie‐Tooth Type 1A

D. Visigalli, A. Schenone, L. Nobbio, 2014, Journal of cellular biochemistry.

Synthesis of GDP-L-fucose by the Human FX Protein*

L. Sturla, A. De Flora, M. Tonetti, 1996, The Journal of Biological Chemistry.

Insulin-independent stimulation of skeletal muscle glucose uptake by low-dose abscisic acid via AMPK activation

L. Sturla, E. Zocchi, A. De Flora, 2020, Scientific Reports.

Extracellular ATP enhances mRNA levels of nitric oxide synthase and TNF-alpha in lipopolysaccharide-treated RAW 264.7 murine macrophages.

L. Sturla, A. De Flora, M. Tonetti, 1995, Biochemical and biophysical research communications.

Genetic variation in the quantitative levels of an NADP (H)-binding protein (FX) in human erythrocytes.

A. De Flora, A. Morelli, S. Pontremoli, 1981, Blood.

Evidence for the modification of fructose 1,6-bisphosphatase by two distinct lysosomal proteases.

A. De Flora, B. Horecker, E. Melloni, 1974, Biochemical and biophysical research communications.

Ligand-induced conformational states of rabbit liver fructose 1,6-bisphosphatase as revealed by digestion with subtilisin.

A. De Flora, B. Horecker, E. Melloni, 1973, Archives of biochemistry and biophysics.

The high-resolution crystal structure of periplasmic Haemophilus influenzae NAD nucleotidase reveals a novel enzymatic function of human CD73 related to NAD metabolism.

L. Sturla, A. De Flora, S. Bruzzone, 2012, The Biochemical journal.

Spatio-temporal propagation of Ca2+ signals by cyclic ADP-ribose in 3T3 cells stimulated via purinergic P2Y receptors

E. Zocchi, A. De Flora, S. Bruzzone, 2003, The Journal of cell biology.

Induction by 7,12-dimethylbenz(a)anthracene of molecular and biochemical alterations in transformed human mammary epithelial stem cells, and protection by N-acetylcysteine.

S. De Flora, F. D'Agostini, A. Izzotti, 2006, International journal of oncology.

Purification of glucose 6-phosphate dehydrogenase from human erythrocytes.

R. Cancedda, A. De Flora, A. Bonsignore, 1970, The Italian journal of biochemistry.

Human erythrocyte glucose 6-phosphate dehydrogenase. Evidence for competitive binding of NADP and NADPH.

A. De Flora, A. Morelli, U. Benatti, 1976, Biochemical and biophysical research communications.

Sirtuin 6 Regulates the Activation of the ATP/Purinergic Axis in Endothelial Cells

A. Balduini, A. De Flora, S. Bruzzone, 2023, International journal of molecular sciences.

Autocrine abscisic acid mediates the UV‐B‐induced inflammatory response in human granulocytes and keratinocytes

L. Sturla, Giovanna Basile, E. Zocchi, 2012, Journal of cellular physiology.

The Plant Hormone Abscisic Acid Is a Prosurvival Factor in Human and Murine Megakaryocytes*

A. Balduini, E. Zocchi, A. De Flora, 2017, The Journal of Biological Chemistry.

Cyclic ADP-ribose is a second messenger in the lipopolysaccharide-stimulated proliferation of human peripheral blood mononuclear cells.

C. Usai, A. De Flora, S. Bruzzone, 2003, The Biochemical journal.

Improved metabolic properties of hexokinase-overloaded human erythrocytes.

E. Zocchi, A. De Flora, M. Magnani, 1988, Biochimica et biophysica acta.

Construction of glucose oxidase-loaded human erythrocytes: a model of oxidative cytotoxicity.

E. Zocchi, A. De Flora, M. Tonetti, 1986, The Italian journal of biochemistry.

Synergistic cytotoxicity of carboplatin and divicine on murine erythroleukemic cells.

L. Sturla, A. De Flora, M. Tonetti, 1994, Biochemical and Biophysical Research Communications - BBRC.

Changes in activity and molecular properties of fructose 1, 6-bisphosphatase during fasting and refeeding.

A. De Flora, B. Horecker, E. Melloni, 1974, Proceedings of the National Academy of Sciences of the United States of America.

Isolation and partial charaterization of an NADP- and NADPH- binding protein from human erythrocytes.

A. De Flora, A. Morelli, 1977, Archives of biochemistry and biophysics.

Targeting antiviral nucleotide analogues to macrophages

A. De Flora, M. Magnani, G. Brandi, 1997, Journal of leukocyte biology.

Azidothymidine homodinucleotide-loaded erythrocytes and bioreactors for slow delivery of the antiretroviral drug azidothymidine.

G. Damonte, A. De Flora, M. Magnani, 1996, Biochemical and biophysical research communications.

Metabolic, desmutagenic and anticarcinogenic effects of N-acetylcysteine.

S. De Flora, A. De Flora, G. Rossi, 1986, Respiration; international review of thoracic diseases.

Extracellular ATP potentiates nitric oxide synthase expression induced by lipopolysaccharide in RAW 264.7 murine macrophages.

L. Sturla, A. De Flora, M. Tonetti, 1994, Biochemical and biophysical research communications.

NAADP+ synthesis from cADPRP and nicotinic acid by ADP-ribosyl cyclases.

I. Moreschi, E. Zocchi, A. De Flora, 2006, Biochemical and biophysical research communications.

The interference of leukocytes and platelets with measurement of clucose-6-phosphate dehydrogenase activity of erythrocytes with low activity variants of the enzyme.

A. De Flora, A. Morelli, E. Melloni, 1981, Blood.

Probing the catalytic mechanism of GDP-4-keto-6-deoxy-d-mannose Epimerase/Reductase by kinetic and crystallographic characterization of site-specific mutants.

M. Bolognesi, C. Rosano, L. Sturla, 2000, Journal of molecular biology.

Present and future approaches to the correction of erythrocyte glucose 6-phosphate dehydrogenase deficiency.

A. De Flora, 1981, Haematologica.

Metabolism of human erythrocyte glucose 6-phosphate dehydrogenase. V. Exchange between free and apoenzyme-bound NADP.

R. Cancedda, A. De Flora, A. Morelli, 1969, The Italian journal of biochemistry.

Binding of abscisic acid to human LANCL2.

L. Sturla, E. Zocchi, A. De Flora, 2011, Biochemical and biophysical research communications.

Metabolism of human erythrocyte glucose‐6‐phosphate dehydrogenase. III ‐ isolation of a protein involved in the 6‐phosphogluconate‐induced inactivation

R. Cancedda, A. De Flora, A. Bonsignore, 1968, FEBS letters.

Defective intracellular activity of GDP‐d‐mannose‐4,6‐dehydratase in leukocyte adhesion deficiency type II syndrome

L. Silengo, L. Sturla, A. De Flora, 1998, FEBS letters.

Autocrine abscisic acid plays a key role in quartz‐induced macrophage activation

G. Damonte, E. Jacchetti, L. Sturla, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.