Y. Takada

Y. Takada, N. Matsuura, N. Kugai, 1998, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Urokinase-type Plasminogen Activator Receptor (CD87) Is a Ligand for Integrins and Mediates Cell-Cell Interaction*

A. Mazar, Y. Takada, D. Cines, 2001, The Journal of Biological Chemistry.

Changing ligand specificities of alphavbeta1 and alphavbeta3 integrins by swapping a short diverse sequence of the beta subunit.

J. Takagi, Y. Takada, J. Meredith, 1997, The Journal of biological chemistry.

In vitro and in vivo consequences of VLA-2 expression on rhabdomyosarcoma cells.

B. Zetter, Y. Takada, N. Matsuura, 1991, Science.

Mechanisms of integrin-mediated virus attachment and internalization process.

Y. Takada, K. Triantafilou, M. Triantafilou, 2001, Critical reviews in immunology.

Identification of putative ligand-binding sites of the integrin α4β1 (VLA-4, CD49d/CD29)

Y. Takada, T. Kamata, W. Puzon, 1995 .

Integrin Binding to the Trimeric Interface of CD40L Plays a Critical Role in CD40/CD40L Signaling

Y. Takada, M. Shimoda, Y. Takada, 2019, The Journal of Immunology.

The integrin-binding defective FGF2 mutants potently suppress FGF2 signalling and angiogenesis

K. Lam, Y. Takada, N. Matsuura, 2017, Bioscience reports.

Insulin-like Growth Factor (IGF) Signaling Requires αvβ3-IGF1-IGF Type 1 Receptor (IGF1R) Ternary Complex Formation in Anchorage Independence, and the Complex Formation Does Not Require IGF1R and Src Activation

Y. Takada, M. Fujita, Y. Takada, 2012, The Journal of Biological Chemistry.

Novel peptide ligands for integrin alpha 4 beta 1 overexpressed in cancer cells.

K. Lam, Y. Takada, J. Mařı́k, 2004, Molecular cancer therapeutics.

Enhanced Expression of Integrin αvβ3 Induced by TGF-β Is Required for the Enhancing Effect of Fibroblast Growth Factor 1 (FGF1) in TGF-β-Induced Epithelial-Mesenchymal Transition (EMT) in Mammary Epithelial Cells

Y. Takada, N. Matsuura, Y. Hamada, 2015, PloS one.

A T cell-binding fragment of fibrinogen can prevent autoimmunity.

N. Mitsiades, C. Mitsiades, Y. Takada, 2010, Journal of autoimmunity.

The C-type lectin domain of CD62P (P-selectin) is an integrin ligand

Y. Takada, Y. Takada, 2022, bioRxiv.

Functional classification of ADAMs based on a conserved motif for binding to integrin alpha 9beta 1: implications for sperm-egg binding and other cell interactions.

E. Engvall, D. Sheppard, Y. Takada, 2002, The Journal of biological chemistry.

Monkey Rotavirus Binding to α2β1 Integrin Requires the α2 I Domain and Is Facilitated by the Homologous β1 Subunit

Y. Takada, S. Londrigan, K. Graham, 2003, Journal of Virology.

Critical amino acid residues for ligand binding are clustered in a predicted beta‐turn of the third N‐terminal repeat in the integrin alpha 4 and alpha 5 subunits.

Y. Takada, A. Irie, T. Kamata, 1995, The EMBO journal.

Identification of putative ligand-binding sites of the integrin α4β1 (VLA-4, CD49d/CD29)

Y. Takada, T. Kamata, W. Puzon, 1995 .

Pro-Inflammatory Chemokines CCL5, CXCL12, and CX3CL1 Bind to and Activate Platelet Integrin αIIbβ3 in an Allosteric Manner

Y. Takada, M. Fujita, Y. Takada, 2022, bioRxiv.

Ligand-induced epitope masking. Dissociation of integrin 51-fibronectin complexes only by monoclonal antibodies with an allosteric mode of action.

M. Humphries, A. Mould, T. Jowitt, 2018 .

An Integrin Binding-defective Mutant of Insulin-like Growth Factor-1 (R36E/R37E IGF1) Acts as a Dominant-negative Antagonist of the IGF1 Receptor (IGF1R) and Suppresses Tumorigenesis but Still Binds to IGF1R*

R. Cardiff, A. Borowsky, S. Lo, 2013, The Journal of Biological Chemistry.

A Dominant-Negative FGF1 Mutant (the R50E Mutant) Suppresses Tumorigenesis and Angiogenesis

Y. Takada, N. Matsuura, M. Fujita, 2013, PloS one.

Identification of proteins that associate with integrin α2 by proteomic analysis in human fibrosarcoma HT‐1080 cells

Y. Takada, T. Isobe, Xiao Han, 2012, Journal of cellular physiology.

Determinants of the Specificity of Rotavirus Interactions with the α2β1 Integrin*

Y. Takada, K. Graham, F. Fleming, 2010, The Journal of Biological Chemistry.

The COOH-Terminal Globular Domain of Fibrinogen γ Chain Suppresses Angiogenesis and Tumor Growth

Y. Takada, Xiaojing Ye, Fu-Tong Liu, 2006 .

Rotaviruses interact with α4β7 and α4β1 integrins by binding the same integrin domains as natural ligands

Y. Takada, K. Graham, F. Fleming, 2005 .

Large-animal models of fulminant hepatic failure

Y. Takada, K. Fukunaga, S. Ishiguro, 2003, Journal of Artificial Organs.

Multiple very late antigen (VLA) heterodimers on platelets. Evidence for distinct VLA-2, VLA-5 (fibronectin receptor), and VLA-6 structures.

A. Sonnenberg, Y. Takada, M. Hemler, 1988, The Journal of biological chemistry.

Promotes Gap Junctional Communication

W. Carter, J. Olerud, Y. Takada, 1998 .

Regulation of Conformation and Ligand Binding Function of Integrin α5β1 by the β1 Cytoplasmic Domain*

Y. Takada, T. Yednock, W. Puzon‐McLaughlin, 1996, The Journal of Biological Chemistry.

The primary structure of the alpha 4 subunit of VLA‐4: homology to other integrins and a possible cell‐cell adhesion function.

M. Elices, Y. Takada, M. Hemler, 1989, The EMBO journal.

Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site

Joerg Kallen, Volker Brinkmann, Christian Bruns, 2001, Nature Medicine.

Integrins α2β1 and α4β1 Can Mediate SA11 Rotavirus Attachment and Entry into Cells

Y. Takada, B. Coulson, M. Hewish, 2000, Journal of Virology.

Fibrinogen-&ggr; C-Terminal Fragments Induce Endothelial Barrier Dysfunction and Microvascular Leak via Integrin-Mediated and RhoA-Dependent Mechanism

S. Yuan, Y. Takada, Mack H. Wu, 2009, Arteriosclerosis, thrombosis, and vascular biology.

Novel peptide ligands for integrin α4β1 overexpressed in cancer cells

Kit S. Lam, Ruiwu Liu, Henry Wang, 2004, Molecular Cancer Therapeutics.

Superoxide dismutase in various tissues from rabbits bearing the Vx-2 carcinoma in the maxillary sinus.

Y. Takada, T. Noguchi, M. Kajiyama, 1982, Cancer research.

Direct integrin binding to insulin-like growth factor-2 through the C-domain is required for insulin-like growth factor receptor type 1 (IGF1R) signaling

Y. Takada, Y. Takada, Jessica Yu, 2017, PloS one.

Kidney alanine: Glyoxylate aminotransferase isoenzymes; species distribution, subcellular distribution and properties

Y. Takada, T. Noguchi, 1980 .

Peroxisomal localization of alanine: glyoxylate aminotransferase in human liver.

Y. Takada, T. Noguchi, 1979, Archives of biochemistry and biophysics.

Distinct Functions of Integrin ct and/3 Subunit Cytoplasmic Domains in Cell Spreading and Formation of Focal Adhesions

Y. Takada, M. Ginsberg, J. Loftus, 1993 .

ADAM12‐mediated focal adhesion formation is differently regulated by β1 and β3 integrins

Y. Takada, R. Fässler, R. Albrechtsen, 2005 .

Characteristics of alanine: glyoxylate aminotransferase from Saccharomyces cerevisiae, a regulatory enzyme in the glyoxylate pathway of glycine and serine biosynthesis from tricarboxylic acid-cycle intermediates.

Y. Takada, T. Noguchi, 1985, The Biochemical journal.

Cross-talk of integrin alpha3beta1 and tissue factor in cell migration.

Y. Takada, W. Ruf, E. Hintermann, 2004, Molecular biology of the cell.

Galectin-3 modulates phagocytosis-induced stellate cell activation and liver fibrosis in vivo.

Y. Takada, D. Hsu, Fu-Tong Liu, 2012, American journal of physiology. Gastrointestinal and liver physiology.

Amino acid residues in the alpha IIb subunit that are critical for ligand binding to integrin alpha IIbbeta 3 are clustered in the beta-propeller model.

T. Springer, Y. Takada, A. Irie, 2001, The Journal of biological chemistry.

Model of the alphaLbeta2 integrin I-domain/ICAM-1 DI interface suggests that subtle changes in loop orientation determine ligand specificity.

M. Sanner, A. Olson, G. Morris, 2002, Proteins.

FGF1 (fibroblast growth factor 1 (acidic))

Y. Takada, S. Mori, 2014 .

Critical role of integrin alpha 5 beta 1 in urokinase (uPA)/urokinase receptor (uPAR, CD87) signaling.

R. Czekay, A. Mazar, Y. Takada, 2003, The Journal of biological chemistry.

Integrin-Using Rotaviruses Bind α2β1 Integrin α2 I Domain via VP4 DGE Sequence and Recognize αXβ2 and αVβ3 by Using VP7 during Cell Entry

Y. Takada, E. Mackow, M. Robinson, 2003, Journal of Virology.

Anti-PF4 (heparin-independent)/PF4 complex induces allosteric activation of integrins αIIbβ3 and αvβ3, a potential mechanism of vaccine-induced thrombotic thrombocytopenia (VITT) and autoimmune diseases

Y. Takada, Chun-Yi Wu, Y. Takada, 2022, bioRxiv.

Plasmin-induced Migration of Endothelial Cells

Y. Takada, W. Ruf, L. Miles, 2002, The Journal of Biological Chemistry.

Optimization of RGD-Containing Cyclic Peptides against αvβ3 Integrin

Yan Wang, Kit S Lam, Wenwu Xiao, 2015, Molecular Cancer Therapeutics.

Combinatorial chemistry identifies high-affinity peptidomimetics against α4β1 integrin for in vivo tumor imaging

Ruiwu Liu, K. Lam, Y. Takada, 2006 .

Enhanced Activity of Transforming Growth Factor β1 (TGF-β1) Bound to Cartilage Oligomeric Matrix Protein*

B. Chromy, Y. Takada, P. D. Di Cesare, 2011, The Journal of Biological Chemistry.

Mutational analysis of cell cycle inhibition by integrin beta1C.

M. Schwartz, Y. Takada, W. Kiosses, 1999, The Journal of biological chemistry.

The Role of the CPNKEKEC Sequence in the β2 Subunit I Domain in Regulation of Integrin αLβ2 (LFA-1)1

N. Hogg, Y. Takada, T. Tarui, 2002, The Journal of Immunology.

Identification of mutations associated with peroxisome-to-mitochondrion mistargeting of alanine/glyoxylate aminotransferase in primary hyperoxaluria type 1

Y. Takada, C. Danpure, P E Purdue, 1990, The Journal of cell biology.

Expression level of integrin α5 on tumour cells affects the rate of metastasis to the kidney

Y. Takada, N. Matsuura, S. Higashiyama, 2003, British Journal of Cancer.

Integrin α3β1 expressed by human colon cancer cells is a major carrier of oncodevelopmental carbohydrate epitopes

Y. Takada, N. Prokopishyn, S. Laferté, 1999 .

Crosstalk between insulin-like growth factor (IGF) receptor and integrins through direct integrin binding to IGF1.

Y. Takada, M. Fujita, Yoshikazu Takada, 2017, Cytokine & growth factor reviews.

Potential Role of Kringle-Integrin Interaction in Plasmin and uPA Actions (A Hypothesis)

Y. Takada, 2012, Journal of biomedicine & biotechnology.

VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/Fibronectin binding site

M. Elices, Y. Takada, M. Hemler, 1990, Cell.

ADAM 23/MDC3, a Human Disintegrin That Promotes Cell Adhesion via Interaction with the αvβ3 Integrin through an RGD-independent Mechanism

C. López-Otín, S. Cal, Y. Takada, 2000 .

Subcellular distribution, and physical and immunological properties of hepatic alanine: glyoxylate aminotransferase isoenzymes in different mammalian species.

Y. Takada, T. Noguchi, 1982, Comparative biochemistry and physiology. B, Comparative biochemistry.

Subcellular distribution of pyruvate (glyoxylate) aminotransferases in rat liver.

Y. Takada, T. Noguchi, E. Okuno, 1978, The Biochemical journal.

Specific Interaction of the Recombinant Disintegrin-like Domain of MDC-15 (Metargidin, ADAM-15) with Integrin αvβ3*

Y. Takada, T. Kamata, W. Puzon‐McLaughlin, 1998, The Journal of Biological Chemistry.

Activated Conformations of Very Late Activation Integrins Detected by a Group of Antibodies (HUTS) Specific for a Novel Regulatory Region(355425) of the Common 1 Chain (*)

C. Cabañas, F. Sánchez‐Madrid, Y. Takada, 1996, The Journal of Biological Chemistry.

Silencing of DLC1 Upregulates PAI-1 Expression and Reduces Migration in Normal Prostate Cells

S. Lo, Y. Takada, Y. Shih, 2011, Molecular Cancer Research.

Integrins αvβ3 and α4β1 Act as Coreceptors for Fractalkine, and the Integrin-Binding Defective Mutant of Fractalkine Is an Antagonist of CX3CR1

Y. Takada, M. Fujita, Y. Takada, 2012, The Journal of Immunology.

Identification of putative ligand binding sites within I domain of integrin α2β1 (VLA-2,CD49b/CD29).

Y. Takada, T. Kamata, W. Puzon, 1996, The Journal of Biological Chemistry.

A novel monoclonal antibody recognizing a cation-dependent epitope within the regulatory loop of human beta(1) integrin (CD29).

Y. Takada, J. Lévesque, P. Simmons, 2002, Hybridoma and hybridomics.

Fibulin-5/DANCE is essential for elastogenesis in vivo

Tasuku Honjo, Susumu Minamisawa, John Ross, 2002, Nature.

Interaction of integrins alpha 3 beta 1 and alpha 2 beta 1: potential role in keratinocyte intercellular adhesion

W. Carter, Y. Takada, B. E. Symington, 1993, The Journal of cell biology.

Angiogenesis , Metastasis , and the Cellular Microenvironment Silencing of DLC 1 Upregulates PAI-1 Expression and Reduces Migration in Normal Prostate Cells

S. Lo, Y. Takada, Y. Shih, 2011 .

Changing Ligand Specificities of αvβ1 and αvβ3 Integrins by Swapping a Short Diverse Sequence of the β Subunit*

J. Takagi, Y. Takada, J. Meredith, 1997, The Journal of Biological Chemistry.

Critical Residues for Ligand Binding in an I Domain-like Structure of the Integrin β1 Subunit*

Y. Takada, W. Puzon‐McLaughlin, Wilma Puzon-McLaughlin, 1996, The Journal of Biological Chemistry.

Identification of a regulatory region of integrin beta 1 subunit using activating and inhibiting antibodies.

Y. Takada, W. Puzon, 1993, The Journal of biological chemistry.

Structural basis of integrin-mediated signal transduction.

Y. Takada, A. Irie, T. Kamata, 1997, Matrix biology : journal of the International Society for Matrix Biology.

Functional Classification of ADAMs Based on a Conserved Motif for Binding to Integrin α9β1

E. Engvall, D. Sheppard, Y. Takada, 2002, The Journal of Biological Chemistry.

Specific interaction of the recombinant disintegrin-like domain of MDC-15 (metargidin, ADAM-15) with integrin alphavbeta3.

Y. Takada, T. Kamata, W. Puzon‐McLaughlin, 1998, The Journal of biological chemistry.

A Point Mutation of Integrin/3 Subunit Blocks Binding of Otsi3 to Fibronectin and Invasin but not Recruitment to Adhesion Plaques

Y. Takada, 2002 .

A point mutation of integrin beta 1 subunit blocks binding of alpha 5 beta 1 to fibronectin and invasin but not recruitment to adhesion plaques

Y. Takada, D. Mandelman, M. Ginsberg, 1992, The Journal of cell biology.

Rotavirus-neutralizing antibodies inhibit virus binding to integrins alpha 2 beta 1 and alpha 4 beta 1.

Y. Takada, K. Graham, F. Fleming, 2007, Archives of virology.

Rotavirus spike protein VP5* binds α2β1 integrin on the cell surface and competes with virus for cell binding and infectivity

Y. Takada, K. Graham, B. Coulson, 2006 .

Rotavirus spike protein VP5* binds alpha2beta1 integrin on the cell surface and competes with virus for cell binding and infectivity.

Y. Takada, K. Graham, B. Coulson, 2006, The Journal of general virology.

Rotaviruses interact with alpha4beta7 and alpha4beta1 integrins by binding the same integrin domains as natural ligands.

Y. Takada, K. Graham, F. Fleming, 2005, The Journal of general virology.

Integrin-using rotaviruses bind alpha2beta1 integrin alpha2 I domain via VP4 DGE sequence and recognize alphaXbeta2 and alphaVbeta3 by using VP7 during cell entry.

Y. Takada, E. Mackow, M. Robinson, 2003, Journal of virology.

Molecular cloning and expression of the cDNA for alpha 3 subunit of human alpha 3 beta 1 (VLA-3), an integrin receptor for fibronectin, laminin, and collagen

Y. Takada, C. Chen, M. Ginsberg, 1991, The Journal of cell biology.

Molecular Cloning and Expression of the cDNA for a 3 Subunit of Human a 3 aJVLA-3), an Integrin Receptor for Fibronectin, Laminin, and Collagen

Y. Takada, M. Ginsberg, E. Murphy, 1991 .

Pro-inflammatory Secretory Phospholipase A2 Type IIA Binds to Integrins αvβ3 and α4β1 and Induces Proliferation of Monocytic Cells in an Integrin-dependent Manner*

Y. Takada, Fu-Tong Liu, C. Hoogland, 2008, Journal of Biological Chemistry.

RGD-independent Binding of Integrin α9β1 to the ADAM-12 and -15 Disintegrin Domains Mediates Cell-Cell Interaction*

D. Sheppard, Y. Takada, A. Sehara-Fujisawa, 2000, The Journal of Biological Chemistry.

The primary structure of the VLA-2/collagen receptor alpha 2 subunit (platelet GPIa): homology to other integrins and the presence of a possible collagen-binding domain

Y. Takada, M. Hemler, Yoshikazu Takada, 1989, The Journal of cell biology.

Specific Interaction of Angiostatin with Integrin αvβ3 in Endothelial Cells*

Y. Takada, L. Miles, T. Tarui, 2001, The Journal of Biological Chemistry.

Effects of fibronectin cleaved by neuropsin on cell adhesion and migration

Y. Takada, N. Matsuura, S. Yoshida, 2001, Neuroscience Research.

Differential regulation of Rho GTPases by beta1 and beta3 integrins: the role of an extracellular domain of integrin in intracellular signaling.

B. Chen, S. Usami, S. Chien, 2002, Journal of cell science.

Human Parechovirus 1 Utilizes Integrins αvβ3 and αvβ1 as Receptors

Y. Takada, N. Fernández, K. Triantafilou, 2000, Journal of Virology.

ADAM12/Syndecan-4 Signaling Promotes β1Integrin-dependent Cell Spreading through Protein Kinase Cα and RhoA*

Y. Takada, A. Mercurio, C. Larsson, 2002, The Journal of Biological Chemistry.

Aromatic-amino acid-glyoxylate aminotransferase from rat liver.

Y. Takada, T. Noguchi, 1987, Methods in enzymology.

The effect of vitamin B6 deficiency on alanine: glyoxylate aminotransferase isoenzymes in rat liver.

Y. Takada, T. Noguchi, T. Mori, 1984, Archives of biochemistry and biophysics.

Enzymatic and immunological comparison of alanine: glyoxylate aminotransferases from different fish and mammalian livers.

Y. Takada, M. Nagano, N. Hanada, 1984, Comparative biochemistry and physiology. B, Comparative biochemistry.

The evolution of peroxisomal and mitochondrial alanine: glyoxylate aminotransferase 1 in mammalian liver.

Y. Takada, T. Noguchi, 1982, Biochemical and biophysical research communications.

Increase in hepatic pyruvate (glyoxylate) aminotransferase activity on administration of clofibrate to the rat.

Y. Takada, T. Noguchi, 1981, Biochemical pharmacology.

Stromal cell-derived factor-1 (CXCL12) activates integrins by direct binding to an allosteric ligand-binding site (site 2) of integrins without CXCR4.

Y. Takada, M. Fujita, Y. Takada, 2018, The Biochemical journal.

Direct interaction of the kringle domain of urokinase-type plasminogen activator (uPA) and integrin αvβ3 induces signal transduction and enhances plasminogen activation

J. Takagi, A. Mazar, Y. Takada, 2006, Thrombosis and Haemostasis.

Direct Binding of Integrin αvβ3 to FGF1 Plays a Role in FGF1 Signaling*

Kit S Lam, Biao Shi, Zi Ma, 2008, Journal of Biological Chemistry.

Defining the topology of integrin alpha5beta1-fibronectin interactions using inhibitory anti-alpha5 and anti-beta1 monoclonal antibodies. Evidence that the synergy sequence of fibronectin is recognized by the amino-terminal repeats of the alpha5 subunit.

S. Aota, M. Humphries, A. Mould, 1997, The Journal of biological chemistry.

Antagonist of CX 3 CR 1 Defective Mutant of Fractalkine Is an for Fractalkine , and the Integrin-Binding Act as Coreceptors 1 β 4 α and 3 β v α Integrins

Y. Takada, M. Fujita, Y. Takada, 2012 .

Adhesion of Gastric Carcinoma Cells to Peritoneum Mediated by α3β1 Integrin (VLA-3)

Y. Takada, Rikio Sano, T. Tsuji, 2004, Cancer Research.

α3β1 Adhesion to Laminin-5 and Invasin: Critical and Differential Role of Integrin Residues Clustered at the Boundary between α3 N-Terminal Repeats 2 and 3†

Y. Takada, A. Irie, X. Zhang, 1999 .

Multiple Discontinuous Ligand-mimetic Antibody Binding Sites Define a Ligand Binding Pocket in Integrin αIIbβ3 *

Y. Takada, T. Kamata, W. Puzon‐McLaughlin, 2000, The Journal of Biological Chemistry.

Regulation of integrin function: evidence that bivalent-cation-induced conformational changes lead to the unmasking of ligand-binding sites within integrin alpha5 beta1.

M. Humphries, A. Mould, Y. Takada, 1998, The Biochemical journal.

Role of integrin alpha(v)beta3 in the early phase of liver metastasis: PET and IVM analyses.

T. Kakiuchi, H. Tsukada, Y. Takada, 2002, Clinical & experimental metastasis.

Multiple ligand binding functions for VLA-2 α2β1 and VLA-3 (α3β1) in the integrin family

B. Zetter, M. Elices, Y. Takada, 1990 .

Multiple ligand binding functions for VLA-2 (alpha 2 beta 1) and VLA-3 (alpha 3 beta 1) in the integrin family.

B. Zetter, M. Elices, Y. Takada, 1990, Cell differentiation and development : the official journal of the International Society of Developmental Biologists.

Propolypeptide of von Willebrand Factor Is a Novel Ligand for Very Late Antigen-4 Integrin*

Yuji Saito, Y. Takada, S. Aimoto, 1997, The Journal of Biological Chemistry.

Cloning and expression of cDNAs for the alpha subunit of the murine lymphocyte-Peyer's patch adhesion molecule

I. Weissman, M. C. Hu, Y. Takada, 1991, The Journal of cell biology.

Mutational Analysis of Cell Cycle Inhibition by Integrin β1C *

Martin A. Schwartz, M. Schwartz, Y. Takada, 1999, The Journal of Biological Chemistry.

Intraperoxisomal and intramitochondrial localization, and assay of pyruvate (glyoxylate) aminotransferase from rat liver.

Y. Takada, T. Noguchi, Y. Oota, 1979, Hoppe-Seyler's Zeitschrift fur physiologische Chemie.

Differential regulation of cellular adhesion and migration by recombinant laminin‐5 forms with partial deletion or mutation within the G3 domain of α3 chain

Y. Kariya, Y. Takada, K. Miyazaki, 2003, Journal of cellular biochemistry.

of the kringle domain of urokinase-type plasminogen activator (uPA) and integrin induces signal transduction and enhances plasminogen activation.

J. Takagi, A. Mazar, Y. Takada, 2006 .

Direct interaction of the kringle domain of urokinase-type plasminogen activator (uPA) and integrin alpha v beta 3 induces signal transduction and enhances plasminogen activation.

J. Takagi, A. Mazar, Y. Takada, 2006, Thrombosis and haemostasis.

Amino Acid Residues in the αIIb Subunit That Are Critical for Ligand Binding to Integrin αIIbβ3 Are Clustered in the β-Propeller Model*

T. Springer, Y. Takada, A. Irie, 2001, The Journal of Biological Chemistry.

Echovirus 1 interaction with the human very late antigen-2 (integrin alpha2beta1) I domain. Identification of two independent virus contact sites distinct from the metal ion-dependent adhesion site.

R. Liddington, J. Emsley, Y. Takada, 1997, The Journal of biological chemistry.

Relocation of α5 subunit to uncover the β1 stalk region

J. Takagi, Yuji Saito, Y. Takada, 1998 .

Anti-Monomeric C-Reactive Protein Antibody Ameliorates Arthritis and Nephritis in Mice

Y. Takada, M. Fujita, Chitose Fujita, 2021, The Journal of Immunology.

Soluble CD40L activates soluble and cell-surface integrin αvβ3, α5β1, and α4β1 by binding to the allosteric ligand-binding site (site 2)

Y. Takada, R. Cheng, M. Shimoda, 2021, The Journal of biological chemistry.

Specific binding of integrin αvβ3 to the fibrinogen γ and α(E) chain C-terminal domains

Y. Takada, L. Medved, X. Zhang, 1999 .

Specific binding of integrin alpha v beta 3 to the fibrinogen gamma and alpha E chain C-terminal domains.

Y. Takada, L. Medved, K. Yokoyama, 1999, Biochemistry.

alpha4beta1- and alpha6beta1-integrins are functional receptors for midkine, a heparin-binding growth factor.

M. Noda, Y. Takada, T. Muramatsu, 2004, Journal of cell science.

Identification of Equine Lactadherin-derived Peptides That Inhibit Rotavirus Infection via Integrin Receptor Competition*

Y. Takada, D. Lembo, A. Civra, 2015, The Journal of Biological Chemistry.

Plasmin-induced Migration Requires Signaling through Protease-activated Receptor 1 and Integrin α9β1*

Y. Takada, W. Ruf, N. Akakura, 2004, Journal of Biological Chemistry.

Novel point mutations in the αIIb subunit (Phe289 → Ser, Glu324 → Lys and Gln747 → Pro) causing thrombasthenic phenotypes in four Japanese patients

Y. Takada, Yasuo Ikeda, M. Murata, 1998, British journal of haematology.

The Role of α and β Chains in Ligand Recognition by β7 Integrins*

K. Tan, Jia-huai Wang, Y. Takada, 2000, The Journal of Biological Chemistry.

The Use of One-Bead One-Compound Combinatorial Library Technology to Discover High-Affinity αvβ3 Integrin and Cancer Targeting Arginine-Glycine-Aspartic Acid Ligands with a Built-in Handle

Felice C Lightstone, Kit S Lam, Ruiwu Liu, 2010, Molecular Cancer Therapeutics.

Structural interlock between ligand-binding site and stalk-like region of beta1 integrin revealed by a monoclonal antibody recognizing conformation-dependent epitope.

J. Takagi, Y. Takada, T. Isobe, 1997, Journal of biochemistry.

A serine-to-phenylalanine substitution leads to loss of alanine:glyoxylate aminotransferase catalytic activity and immunoreactivity in a patient with primary hyperoxaluria type 1.

Y. Takada, P. Purdue, Y. Minatogawa, 1992, Human molecular genetics.

Human peroxisomal L-alanine: glyoxylate aminotransferase. Evolutionary loss of a mitochondrial targeting signal by point mutation of the initiation codon.

H. Esumi, Y. Takada, H Esumi, 1990, The Biochemical journal.

Cellular Interaction of Integrin α3β1 with Laminin 5 Promotes Gap Junctional Communication

W. Carter, J. Olerud, Y. Takada, 1998, The Journal of cell biology.

Expression of integrins to control migration direction of electrotaxis

Y. Takada, Min Zhao, Jianxin Jiang, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

RGD-independent binding of integrin alpha9beta1 to the ADAM-12 and -15 disintegrin domains mediates cell-cell interaction.

D. Sheppard, Y. Takada, A. Sehara-Fujisawa, 2000, The Journal of biological chemistry.

Critical Threonine and Aspartic Acid Residues within the I Domains of β2 Integrins for Interactions with Intercellular Adhesion Molecule 1 (ICAM-1) and C3bi (*)

Y. Takada, T. Kamata, R. Wright, 1995, The Journal of Biological Chemistry.

Identification of putative ligand-binding sites of the integrin alpha 4 beta 1 (VLA-4, CD49d/CD29)

Y. Takada, T. Kamata, W. Puzon, 1995, The Biochemical journal.

Crosstalk between Fibroblast Growth Factor (FGF) Receptor and Integrin through Direct Integrin Binding to FGF and Resulting Integrin-FGF-FGFR Ternary Complex Formation

Y. Takada, S. Mori, 2013 .

THE CELL TO CELL INTERACTION OF BREAST CANCER CELLS REGULATES CANCER INVASION VIA ADAM15

A. Chambers, Y. Takada, Y. Matsui, 2012 .

Interaction between collagen and the α2 I-domain of integrin αβ1: Critical role of conserved residues in the metal ion-dependent adhesion site (MIDAS) region

R. Liddington, Y. Takada, T. Kamata, 1999 .

Defining the Topology of Integrin α5β1-Fibronectin Interactions Using Inhibitory Anti-α5 and Anti-β1 Monoclonal Antibodies

S. Aota, M. Humphries, A. Mould, 1997, The Journal of Biological Chemistry.

Trees and CO2

S. Simon, Y. Takada, Xiaojing Ye, 1996, Environmental Health Perspectives.

1 as Receptors β v α 3 and β v α Human Parechovirus 1 Utilizes Integrins

Y. Takada, N. Fernández, K. Triantafilou, 2014 .

Combinatorial chemistry identifies high-affinity peptidomimetics against alpha4beta1 integrin for in vivo tumor imaging.

Kit S Lam, Li Peng, Ruiwu Liu, 2006, Nature chemical biology.

The C-type lectin domain of CD62P (P-selectin) functions as an integrin ligand

S. Simon, Y. Takada, Y. Takada, 2023, Life Science Alliance.

Degradation of uric acid to urea and glyoxylate in peroxisomes.

Y. Takada, S. Fujiwara, T. Noguchi, 1979, The Journal of biological chemistry.

Multiple loop structures critical for ligand binding of the integrin alpha4 subunit in the upper face of the beta-propeller mode 1.

Y. Takada, A. Irie, T. Kamata, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Regulation of conformation and ligand binding function of integrin alpha5beta1 by the beta1 cytoplasmic domain.

Y. Takada, T. Yednock, W. Puzon‐McLaughlin, 1996, The Journal of biological chemistry.

Structure and Function of Integrin Extracellular Domain

Y. Takada, K. Yokoyama, 1998 .

Adhesion of gastric carcinoma cells to peritoneum mediated by alpha3beta1 integrin (VLA-3).

Y. Takada, Rikio Sano, T. Tsuji, 2004, Cancer research.

Plasmin-induced migration requires signaling through protease-activated receptor 1 and integrin alpha(9)beta(1).

Y. Takada, W. Ruf, N. Akakura, 2004, The Journal of biological chemistry.

Glutamate-glyoxylate aminotransferase in rat liver cytosol. Purification, properties and identity with alanine-2-oxoglutarate aminotransferase.

Y. Takada, T. Noguchi, R. Kido, 1977, Hoppe-Seyler´s Zeitschrift für physiologische Chemie.

High affinity interactions of Coxsackievirus A9 with integrin αvβ3 (CD51/61) require the CYDMKTTC sequence of β3, but do not require the RGD sequence of the CAV-9 VP1 protein

Y. Takada, N. Fernández, K. Triantafilou, 2000 .

The 'ligand-induced conformational change' of alpha 5 beta 1 integrin. Relocation of alpha 5 subunit to uncover the beta 1 stalk region.

J. Takagi, Yuji Saito, Y. Takada, 1998, Journal of cell science.

The COOH-terminal globular domain of fibrinogen gamma chain suppresses angiogenesis and tumor growth.

Y. Takada, Xiaojing Ye, Fu-Tong Liu, 2006, Cancer Research.

The degradation of urate in liver peroxisomes. Association of allantoinase with allantoicase in amphibian liver but not in fish and invertebrate liver.

Y. Takada, T. Noguchi, 1983, The Journal of biological chemistry.

Metabolism of urea and glyoxylate, degradative products of purines in marine animals.

Y. Takada, M. Nagano, T. Mori, 1982, Journal of biochemistry.

The role of alpha and beta chains in ligand recognition by beta 7 integrins.

Y. Takada, A. Irie, M. Brenner, 2000, The Journal of biological chemistry.

Interaction between Collagen and the α2 I-domain of Integrin α2β1

R. Liddington, Y. Takada, T. Kamata, 1999, The Journal of Biological Chemistry.

Purification and properties of peroxisomal pyruvate (glyoxylate) aminotransferase from rat liver.

Y. Takada, T. Noguchi, 1978, The Biochemical journal.

Integrin alpha3beta1 expressed by human colon cancer cells is a major carrier of oncodevelopmental carbohydrate epitopes.

Y. Takada, N. Prokopishyn, S. Laferté, 1999, Journal of Cellular Biochemistry.

Platelet integrin alphaIIbbeta3-ligand interactions: what can we learn from the structure?

Y. Takada, T. Kamata, 2001, International journal of hematology.

A Novel Fibroblast Growth Factor-1 (FGF1) Mutant that Acts as an FGF Antagonist

Y. Takada, M. Fujita, Y. Takada, 2010, PloS one.

CD40L Activates Platelet Integrin αIIbβ3 by Binding to the Allosteric Site (Site 2) in a KGD-Independent Manner and HIGM1 Mutations Are Clustered in the Integrin-Binding Sites of CD40L

Y. Takada, M. Shimoda, Y. Takada, 2023, Cells.

Pro-inflammatory Secretory Phospholipase A 2 Type IIA Binds to Integrins

K. Lam, Y. Takada, Fu-Tong Liu, 2008 .

Critical residues of integrin alphaIIb subunit for binding of alphaIIbbeta3 (glycoprotein IIb-IIIa) to fibrinogen and ligand-mimetic antibodies (PAC-1, OP-G2, and LJ-CP3).

Y. Takada, A. Irie, T. Kamata, 1996, The Journal of biological chemistry.

ADAM12-mediated focal adhesion formation is differently regulated by beta1 and beta3 integrins.

Y. Takada, R. Fässler, R. Albrechtsen, 2005, FEBS letters.

Molecular basis of ligand recognition by integrin alpha5beta 1. II. Specificity of arg-gly-Asp binding is determined by Trp157 OF THE alpha subunit.

M. Humphries, A. Mould, Y. Takada, 2000, The Journal of biological chemistry.

Platelet Integrin αIIbβ3-Ligand Interactions: What Can We Learn From the Structure?

Y. Takada, T. Kamata, 2001 .

Effects on rotavirus cell binding and infection of monomeric and polymeric peptides containing alpha2beta1 and alphaxbeta2 integrin ligand sequences.

Y. Takada, D. Jackson, K. Graham, 2004, Journal of virology.

The Binding of Monomeric C-Reactive Protein (mCRP) to Integrins αvβ3 and α4β1 Is Related to Its Pro-Inflammatory Action

Y. Takada, M. Fujita, Y. Takada, 2014, PloS one.

The Binding of Monomeric C-Reactive Protein ( mCRP ) to Integrins a v b 3 and a 4 b 1 Is Related to Its Pro-Inflammatory Action

Y. Takada, M. Fujita, Y. Takada, 2014 .

Antagonist of Cx3cr1 Defective Mutant of Fractalkine Is an for Fractalkine, and the Integrin-binding

Y. Takada, M. Fujita, Y. Takada, 2022 .

Distinct Functions of Integrin ct and/3 Subunit Cytoplasmic Domains in Cell Spreading and Formation of Focal Adhesions

Y. Takada, M. Ginsberg, J. Loftus, 1993 .

Multiple discontinuous ligand-mimetic antibody binding sites define a ligand binding pocket in integrin alpha(IIb)beta(3).

Y. Takada, T. Kamata, W. Puzon‐McLaughlin, 2000, Journal of Biological Chemistry.

Identification of inhibitors against interaction between pro-inflammatory sPLA2-IIA protein and integrin αvβ3.

John M. Knapp, K. Lam, Y. Takada, 2013, Bioorganic & medicinal chemistry letters.