D. F. Carlson

发表

Genetically engineered minipigs model the major clinical features of human neurofibromatosis type 1

D. Largaespada, A. Stemmer-Rachamimov, M. Giovannini, 2018, Communications Biology.

In vivo Genome Editing Using High Efficiency TALENs

Colby G Starker, D. Voytas, S. Ekker, 2012, Nature.

Genome edited sheep and cattle

C. Whitelaw, S. Lillico, D. F. Carlson, 2014, Transgenic Research.

NMR structural analysis of Sleeping Beauty transposase binding to DNA

D. F. Carlson, P. Hackett, E. Aronovich, 2014, Protein science : a publication of the Protein Society.

Identifying secretomes in people, pufferfish and pigs.

Eric W Klee, Lynda B M Ellis, S. Ekker, 2004, Nucleic acids research.

Precision editing of large animal genomes.

D. F. Carlson, S. Fahrenkrug, P. Hackett, 2012, Advances in genetics.

Peripheral vascular atherosclerosis in a novel PCSK9 gain‐of‐function mutant Ossabaw miniature pig model

L. Lerman, D. F. Carlson, A. Lerman, 2018, Translational research : the journal of laboratory and clinical medicine.

Pigs taking wing with transposons and recombinases

K. Clark, D. F. Carlson, S. Fahrenkrug, 2007, Genome Biology.

Dysregulated ribonucleoprotein granules promote cardiomyopathy in RBM20 gene-edited pigs

Angela R. Miller, Timothy J. Nelson, L. Steinmetz, 2020, Nature Medicine.

Application of the Sleeping Beauty transposon system to avian cells.

D. F. Carlson, S. Fahrenkrug, B. Kong, 2008, Animal genetics.

Enzymatic engineering of the porcine genome with transposons and recombinases

K. Clark, D. F. Carlson, S. Fahrenkrug, 2007, BMC biotechnology.

Strategies for selection marker-free swine transgenesis using the Sleeping Beauty transposon system

K. Clark, D. F. Carlson, S. Fahrenkrug, 2011, Transgenic Research.

TALEN‐mediated gene targeting in porcine spermatogonia

D. F. Carlson, S. Fahrenkrug, I. Dobrinski, 2018, Molecular reproduction and development.

Efficient introgression of allelic variants by embryo-mediated editing of the bovine genome

D. F. Carlson, S. Fahrenkrug, G. Laible, 2015, Scientific Reports.

The Promises and Challenges of Precision Gene Editing in Animals of Agricultural Importance

D. F. Carlson, S. Fahrenkrug, P. Hackett, 2015 .

In vivo genome editing using a high-efficiency TALEN system

D. Voytas, G. Colby, S. Ekker, 2020 .

Targeted Gene Editing in Porcine Spermatogonia

D. F. Carlson, I. Dobrinski, Dennis A. Webster, 2021, Frontiers in Genetics.

Live pigs produced from genome edited zygotes

B. Whitelaw, C. Whitelaw, S. Lillico, 2013, Scientific Reports.

GeneWeld: a method for efficient targeted integration directed by short homology

Carla M. Mann, Stephen C. Ekker, Chi-Bin Chien, 2018, bioRxiv.

Influence of oocyte selection, activation with a zinc chelator and inhibition of histone deacetylases on cloned porcine embryo and chemically activated oocytes development

D. F. Carlson, M. Bertolini, F. Ongaratto, 2020, Zygote.

Editing Myosin VB Gene to Create Porcine Model of Microvillus Inclusion Disease, With Microvillus-lined Inclusions and Alterations in Sodium Transporters.

Alex Coutts, D. F. Carlson, J. Goldenring, 2020, Gastroenterology.

Editing livestock genomes with site-specific nucleases.

D. F. Carlson, S. Fahrenkrug, P. Hackett, 2014, Reproduction, fertility, and development.

Efficient nonmeiotic allele introgression in livestock using custom endonucleases

D. F. Carlson, S. Fahrenkrug, P. Hackett, 2013, Proceedings of the National Academy of Sciences.

Production of hornless dairy cattle from genome-edited cell lines

T. Sonstegard, D. F. Carlson, S. Fahrenkrug, 2016, Nature Biotechnology.

Liver development is restored by blastocyst complementation of HHEX knockout in mice and pigs

J. Dutton, C. Steer, W. Low, 2021, Stem cell research & therapy.

Development of a porcine model of phenylketonuria with a humanized R408W mutation for gene editing

D. F. Carlson, A. Watson, R. A. Kaiser, 2021, PloS one.

Engineered Swine Models of Cancer

D. Largaespada, D. F. Carlson, S. Fahrenkrug, 2016, Front. Genet..

Mammalian germ cells are determined after PGC colonization of the nascent gonad

D. Page, M. Carmell, D. F. Carlson, 2019, Proceedings of the National Academy of Sciences.

CRISPR/Cas9-editing of KISS1 to generate pigs with hypogonadotropic hypogonadism as a castration free trait

T. Sonstegard, Alex Coutts, D. F. Carlson, 2023, Frontiers in Genetics.

Efficient targeted integration directed by short homology in zebrafish and mammalian cells

Carla M. Mann, Beau R. Webber, D. Dobbs, 2020, eLife.

Evaluating Large Spontaneous Deletions in a Bovine Cell Line Selected for Bovine Viral Diarrhea Virus Resistance

G. Harhay, T. Kalbfleisch, M. P. Heaton, 2021, Viruses.

Interspecies Organogenesis for Human Transplantation

Venkatramana D. Krishna, Rajagopal N. Aravalli, J. Dutton, 2019, Cell transplantation.

307 Precision animal breeding to make genetically castrated animals for improved animal welfare and alternative breeding applications

T. Sonstegard, D. F. Carlson, S. Fahrenkrug, 2017 .

Efficient edition of the bovine PRNP prion gene in somatic cells and IVF embryos using the CRISPR/Cas9 system.

D. F. Carlson, S. Fahrenkrug, H. Niemann, 2016, Theriogenology.

The NIH Somatic Cell Genome Editing program

David R. Liu, Benjamin S. Freedman, Daniel G. Anderson, 2021, Nature.

Passport , a native Tc 1 / mariner transposon from flatfish is functionally active in vertebrate cells

K. Clark, D. F. Carlson, S. Fahrenkrug, 2010 .

Passport, a native Tc1 transposon from flatfish, is functionally active in vertebrate cells

K. Clark, D. F. Carlson, S. Fahrenkrug, 2009, Nucleic acids research.

Efficient TALEN-mediated gene knockout in livestock

Daniel F. Voytas, Scott C. Fahrenkrug, Wenfang Tan, 2012, Proceedings of the National Academy of Sciences.

337 NONMEIOTIC INTROGRESSION OF QUANTITATIVE TRAIT NUCLEOTIDES AND CORRECTION OF CONGENITAL MUTATIONS IN LIVESTOCK WITH TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR NUCLEASES

C. Whitelaw, S. Lillico, D. F. Carlson, 2013 .

Efficient mammalian germline transgenesis by cis-enhanced Sleeping Beauty transposition

John R. Garbe, Scott C. Fahrenkrug, David A. Largaespada, 2010, Transgenic Research.

Efficient TALEN-mediated gene targeting of chicken primordial germ cells

A. Sherman, D. F. Carlson, S. Fahrenkrug, 2017, Development.

Targeting G with TAL Effectors: A Comparison of Activities of TALENs Constructed with NN and NK Repeat Variable Di-Residues

Daniel F. Voytas, Adam J. Bogdanove, Philip Bradley, 2012, PloS one.

CXM: a new tool for mapping breast cancer risk in the tumor microenvironment.

P. LaViolette, H. Jacob, J. Lazar, 2014, Cancer research.

Targeting DNA With Fingers and TALENs

D. F. Carlson, S. Fahrenkrug, P. Hackett, 2012, Molecular therapy. Nucleic acids.

Dysregulated ribonucleoprotein granules promote cardiomyopathy in RBM20 gene-edited pigs

Angela R. Miller, L. Steinmetz, M. Hathcock, 2020, Nature Medicine.

First gene-edited calf with reduced susceptibility to a major viral pathogen

G. Harhay, T. Kalbfleisch, M. P. Heaton, 2022, bioRxiv.

Accumulation of Pericardial Fat Is Associated With Alterations in Heart Rate Variability Patterns in Hypercholesterolemic Pigs

I. Patras, L. Lerman, D. F. Carlson, 2020, Circulation. Arrhythmia and electrophysiology.

Abstracts: UC Davis Transgenic Animal Research Conference VI

K. Clark, A. Gutiérrez-Adán, D. F. Carlson, 2007, Transgenic Research.

TALEN-based gene correction for epidermolysis bullosa.

Christof von Kalle, Jakub Tolar, Richard Gabriel, 2013, Molecular therapy : the journal of the American Society of Gene Therapy.

Ossabaw Pigs With a PCSK9 Gain‐of‐Function Mutation Develop Accelerated Coronary Atherosclerotic Lesions: A Novel Model for Preclinical Studies

R. Virmani, F. Kolodgie, L. Lerman, 2018, Journal of the American Heart Association.

Genetically engineered minipigs model the major clinical features of human neurofibromatosis type 1

D. Largaespada, A. Stemmer-Rachamimov, M. Giovannini, 2018, Communications Biology.

A Stem Cell Reporter for Investigating Pluripotency and Self-Renewal in the Rat

A. Joshi, Tamir Chandra, D. F. Carlson, 2019, Stem cell reports.

Simple and Efficient Methods for Enrichment and Isolation of Endonuclease Modified Cells

D. Largaespada, B. Moriarity, D. F. Carlson, 2014, PloS one.

Cattle with a precise, zygote-mediated deletion safely eliminate the major milk allergen beta-lactoglobulin

D. Wells, D. F. Carlson, S. Fahrenkrug, 2018, Scientific Reports.

328 VERSATILE TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR NUCLEASE (TALEN)-MEDIATED ENGINEERING OF OSSABAW MINIATURE SWINE

D. F. Carlson, S. Fahrenkrug, W. Tan, 2013 .

Cattle with a precise, zygote-mediated deletion safely eliminate the major milk allergen beta-lactoglobulin

D. Wells, D. F. Carlson, S. Fahrenkrug, 2018, Scientific reports.

A reduction of primary cilia but not hedgehog signaling disrupts morphogenesis in testicular organoids

D. F. Carlson, I. Dobrinski, S. Sakib, 2020, Cell and Tissue Research.

Efficient TALEN-mediated gene knockout in livestock

D. Voytas, C. Whitelaw, S. Lillico, 2012, Proceedings of the National Academy of Sciences.

Efficient TALEN-mediated gene targeting of chicken primordial germ cells

A. Sherman, D. F. Carlson, S. Fahrenkrug, 2017, Development.

Efficient edition of the bovine PRNP prion gene in somatic cells and IVF embryos using the CRISPR/Cas9 system.

D. F. Carlson, S. Fahrenkrug, R. Bevacqua, 2016, Theriogenology.

Efficient nonmeiotic allele introgression in livestock using custom endonucleases

D. F. Carlson, S. Fahrenkrug, P. Hackett, 2013, Proceedings of the National Academy of Sciences.

Live pigs produced from genome edited

D. F. Carlson, S. Fahrenkrug, Dana Štveráková, 2013 .

Enzymatic engineering of the porcine genome with transposons and recombinases

K. Clark, D. F. Carlson, S. Fahrenkrug, 2007, BMC biotechnology.

CXM: a new tool for mapping breast cancer risk in the tumor microenvironment.

P. LaViolette, H. Jacob, J. Shull, 2014, Cancer research.

A reduction of primary cilia but not hedgehog signaling disrupts morphogenesis in testicular organoids

D. F. Carlson, I. Dobrinski, S. Sakib, 2020, Cell and Tissue Research.

Enzymatic engineering of the porcine genome with transposons and recombinases

P Weinstein, P. Weinstein, D. F. Carlson, 2007, BMC biotechnology.