S. O’Keeffe

发表

A Global View of Gene Activity and Alternative Splicing by Deep Sequencing of the Human Transcriptome

Marcel H. Schulz, S. Haas, H. Lehrach, 2008, Science.

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

T. Maniatis, Chaolin Zhang, B. Barres, 2014, The Journal of Neuroscience.

A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model.

R. Myers, Saeed Tavazoie, T. Maniatis, 2013, Cell reports.

Transcription factor binding predictions using TRAP for the analysis of ChIP-seq data and regulatory SNPs

Helge G. Roider, M. Vingron, Morgane Thomas-Chollier, 2011, Nature Protocols.

The extracellular Leucine-Rich Repeat superfamily; a comparative survey and analysis of evolutionary relationships and expression patterns

K. Hokamp, K. Mitchell, G. Tear, 2007, BMC Genomics.

X-exome sequencing of 405 unresolved families identifies seven novel intellectual disability genes

K. Friend, M. Shaw, E. Haan, 2015, Molecular Psychiatry.

The extracellular Leucine-Rich Repeat superfamily; a comparative survey and analysis of evolutionary relationships and expression patterns

K. Hokamp, K. Mitchell, G. Tear, 2009, BMC Genomics.

Exome sequencing and characterization of 49,960 individuals in the UK Biobank

Alexander E. Lopez, Alexander Hanbo Li, Andrew L Blumenfeld, 2020, Nature.

Global effects of the CSR-1 RNA interference pathway on transcriptional landscape

R. Sachidanandam, S. Hoersch, A. Grishok, 2014, Nature Structural &Molecular Biology.

Antisense lncRNA Transcription Mediates DNA Demethylation to Drive Stochastic Protocadherin α Promoter Choice

T. Maniatis, S. Lomvardas, Daniele Canzio, 2019, Cell.

Accelerated High-Yield Generation of Limb-Innervating Motor Neurons from Human Stem Cells

Derek H. Oakley, Mackenzie W. Mathis, H. Wichterle, 2013, The Journal of Neuroscience.

Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations

Tom R. Gaunt, Alexander E. Lopez, Laurent F. Thomas, 2021, Cell.

Combinatorial Binding in Human and Mouse Embryonic Stem Cells Identifies Conserved Enhancers Active in Early Embryonic Development

Martin Vingron, Hans Lehrach, Sean O'Keeffe, 2011, PLoS Comput. Biol..

Gene-level analysis of rare variants in 379,066 whole exome sequences identifies an association of GIGYF1 loss of function with type 2 diabetes

Alexander E. Lopez, Dustin N. Hartzel, Andrew L Blumenfeld, 2021, Scientific Reports.

Pan-ancestry exome-wide association analyses of COVID-19 outcomes in 586,157 individuals

J. Marchini, G. Abecasis, H. Kang, 2021, The American Journal of Human Genetics.

A catalog of associations between rare coding variants and COVID-19 outcomes

Alexander Hanbo Li, J. Marchini, J. Szustakowski, 2020, medRxiv : the preprint server for health sciences.

Intricate interplay between astrocytes and motor neurons in ALS

R. Myers, J. Tapia, T. Maniatis, 2013, Proceedings of the National Academy of Sciences.

Exome sequencing of 628,388 individuals identifies common and rare variant associations with clonal hematopoiesis phenotypes

J. Marchini, G. Atwal, Y. Houvras, 2022, medRxiv.

The RNA transport element RTE is essential for IAP LTR-retrotransposon mobility.

S. O’Keeffe, G. Pavlakis, A. Zolotukhin, 2008, Virology.

Sour Sensing from the Tongue to the Brain

C. Zuker, S. O’Keeffe, Hao Jin, 2019, Cell.

PASTAA: identifying transcription factors associated with sets of co-regulated genes

Martin Vingron, Thomas Manke, Helge G. Roider, 2008, Bioinform..

hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function

J. Tapia, T. Maniatis, E. Olson, 2015, Proceedings of the National Academy of Sciences.

The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice

T. Maniatis, C. Lutz, Daniele Canzio, 2020, Neuron.

Pcdhαc2 is required for axonal tiling and assembly of serotonergic circuitries in mice

R. Hen, George Mountoufaris, T. Maniatis, 2017, Science.

Multicluster Pcdh diversity is required for mouse olfactory neural circuit assembly

George Mountoufaris, T. Maniatis, F. Polleux, 2017, Science.

LitMiner and WikiGene: identifying problem-related key players of gene regulation using publication abstracts

Thomas Werner, Ralf Schneider, Korbinian Grote, 2005, Nucleic Acids Res..

The Helmholtz Network for Bioinformatics: an integrative web portal for bioinformatics resources

Martin Vingron, Christian von Mering, Ines Liebich, 2004, Bioinform..

The extracellular Leucine-Rich Repeat superfamily; a comparative survey and analysis of evolutionary relationships and expression patterns

K. Hokamp, K. Mitchell, G. Tear, 2007, BMC Genomics.

A catalog of associations between rare coding variants and COVID-19 outcomes

Alexander Hanbo Li, J. Marchini, J. Szustakowski, 2020, medRxiv : the preprint server for health sciences.

A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model.

R. Myers, Saeed Tavazoie, T. Maniatis, 2013, Cell reports.

Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations

Tom R. Gaunt, Alexander E. Lopez, Laurent F. Thomas, 2021, Cell.

The RNA transport element RTE is essential for IAP LTR-retrotransposon mobility.

S. O’Keeffe, G. Pavlakis, A. Zolotukhin, 2008, Virology.

The extracellular Leucine-Rich Repeat superfamily; a comparative survey and analysis of evolutionary relationships and expression patterns

K. Hokamp, K. Mitchell, G. Tear, 2007, BMC Genomics.