D. Marmé

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PTK 787 / ZK 222584 , a Novel and Potent Inhibitor of Vascular Endothelial Growth Factor Receptor Tyrosine Kinases , Impairs Vascular Endothelial Growth Factor-induced Responses and Tumor Growth after Oral Administration

Martin R. Schneider, J. Mestan, F. Totzke, 2000 .

Protein kinase Cα activates RAF-1 by direct phosphorylation

Walter Kolch, Richard Hummel, Harald Mischak, 1993, Nature.

Anthraquinones and betaenone derivatives from the sponge-associated fungus Microsphaeropsis species: novel inhibitors of protein kinases.

F. Totzke, D. Marmé, P. Proksch, 2000, Journal of natural products.

Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976.

G. Martiny-Baron, G. Kochs, H. Mischak, 1993, The Journal of biological chemistry.

Implications of Vascular Endothelial Growth Factor, sFlt-1, and sTie-2 in Plasma, Serum and Cerebrospinal Fluid during Cerebral Ischemia in Man

J. Zentner, J. Drevs, D. Marmé, 2003, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Hypoxia-induced transcription of the vascular endothelial growth factor gene is independent of functional AP-1 transcription factor.

D. Marmé, G. Finkenzeller, A. Technau, 1995, Biochemical and biophysical research communications.

Soluble Tie2 and Flt1 extracellular domains in serum of patients with renal cancer and response to antiangiogenic therapy.

A. Harris, N. Dobbs, D. Marmé, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

Endoglin (CD105) expression in squamous cell carcinoma of the oral cavity

D. Marmé, R. Schimming, 2002, Head & neck.

Activated Neu/ErbB-2 Induces Expression of the Vascular Endothelial Growth Factor Gene by Functional Activation of the Transcription Factor Sp 1

W. Zimmermann, D. Marmé, G. Finkenzeller, 2004, Angiogenesis.

Transmyocardial laser revascularization combined with vascular endothelial growth factor 121 (VEGF121) gene therapy for chronic myocardial ischemia--do the effects really add up?

D. Marmé, F. Beyersdorf, C. Heilmann, 2003, European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery.

Expression of biologically active isoforms of the tumor angiogenesis factor VEGF in Escherichia coli.

G. Martiny-Baron, G. Siemeister, D. Marmé, 1996, Biochemical and biophysical research communications.

VEGF121 induces proliferation of vascular endothelial cells and expression of flk-1 without affecting lymphatic vessels of chorioallantoic membrane.

G. Martiny-Baron, D. Marmé, A. Eichmann, 1996, Developmental biology.

Identification of calmodulin in the green alga Mougeotia and its possible function in chloroplast reorientational movement

D. Marmé, G. Wagner, P. Dieter, 1984, Planta.

Soluble markers for the assessment of biological activity with PTK787/ZK 222584 (PTK/ZK), a vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor in patients with advanced colorectal cancer from two phase I trials.

J. Wood, J. Pinheiro, J. Drevs, 2005, Annals of oncology : official journal of the European Society for Medical Oncology.

Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression.

W. Kolch, G. Brandner, D. Marmé, 1994, Oncogene.

Growth Inhibiting Effects of Progesterone, 17β-Estradiol and 2-Methoxyestradiol on Human Endothelial Cells

D. Marmé, C. Keck, B. Barleon, 2006 .

Vascular endothelial growth factor up-regulates its receptor fms-like tyrosine kinase 1 (FLT-1) and a soluble variant of FLT-1 in human vascular endothelial cells.

G. Martiny-Baron, G. Siemeister, D. Marmé, 1997, Cancer research.

Gö 6976, a selective inhibitor of protein kinase C, is a potent antagonist of human immunodeficiency virus 1 induction from latent/low-level-producing reservoir cells in vitro.

D. Marmé, W. May, C. Schächtele, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Novel indolocarbazole protein kinase C inhibitors prevent reactivation of HIV-1 in latently infected cells.

D. Marmé, C. Schächtele, S. Pätzold, 1993, Antiviral research.

Cloning and functional analysis of the hematopoietic cell‐specific phospholipase Cγ 2 promoter

M. Ueffing, D. Eick, H. Hug, 1996 .

Distribution of calmodulin-stimulated ca transport into membrane vesicles from green spinach leaves.

D. Marmé, H. Greppin, C. Penel, 1983, Plant physiology.

A calmodulin‐dependent, microsomal ATPase from corn (Zea mays L.)

D. Marmé, P. Dieter, 1981 .

PHYTOCHROME: MEMBRANES AS POSSIBLE SITES OF PRIMARY ACTION

D. Marmé, 1977 .

Biochemical characterization of binding sites for dihydropyridine and omega-conotoxin in brain of adult chicken.

R. Woscholski, H. Hug, D. Marmé, 1992, Biochemical and biophysical research communications.

Targeting Vascular Endothelial Growth Factor Pathway Offers New Possibilities to Counteract Microvascular Disturbances During Ischemia/Reperfusion of the Pancreas

D. Marmé, U. Hopt, E. von Dobschuetz, 2006, Transplantation.

In Vivo Properties of Membrane-bound Phytochrome.

D. Marmé, W. Briggs, J. Boisard, 1974, Plant physiology.

Human chorionic gonadotropin-dependent expression of vascular endothelial growth factor/vascular permeability factor in human granulosa cells: importance in ovarian hyperstimulation syndrome.

M. Breckwoldt, D. Marmé, C. Keck, 1995, The Journal of clinical endocrinology and metabolism.

Personalized Cancer Medicine

D. Marmé, M. Hallek, 2012, Oncology Research and Treatment.

Detection and quantification of vascular endothelial growth factor/vascular permeability factor in brain tumor tissue and cyst fluid: the key to angiogenesis?

J. Moringlane, D. Marmé, H. Weich, 1994, Neurosurgery.

Calcium and Cell Physiology

D. Marmé, 1985, Springer Berlin Heidelberg.

Activation and substrate specificity of the human protein kinase C α and ζ isoenzymes

G. Kochs, H. Hug, D. Marmé, 1993 .

Inducible overexpression of human protein kinase C alpha in NIH 3T3 fibroblasts results in growth abnormalities.

H. Hug, D. Marmé, G. Finkenzeller, 1992, Cellular signalling.

Inducible expression of human phospholipase C-gamma 2 and its activation by platelet-derived growth factor B-chain homodimer and platelet-derived growth factor A-chain homodimer in transfected NIH 3T3 fibroblasts.

F. Totzke, H. Hug, D. Marmé, 1992, European journal of biochemistry.

High‐efficiency expression of rat protein kinase C‐γ in baculovirus‐infected insect cells

B. Fiebich, H. Hug, D. Marmé, 1990 .

Regulation of Free Cytoplasmic Calcium: A Role for Phosphatidylinositol Metabolism and G-Proteins

D. Marmé, 1990 .

Sequence of human protein kinase C α

H. Hug, D. Marmé, G. Finkenzeller, 1990 .

Changes in serum soluble VEGFR-1 and Tie-2 receptors in colorectal cancer patients following surgical resections.

J. Monson, D. Marmé, E. Gardiner, 2004, Anticancer research.

Calmodulin content and activity of Ca2+-ATPase and phospholipase A2 in rat Kupffer cells.

D. Marmé, K. Decker, M. Birmelin, 1984, European journal of biochemistry.

Induction of the blood–brain barrier marker neurothelin/HT7 in endothelial cells by a variety of tumors in chick embryos

D. Marmé, C. Schächtele, F. Pröls, 2000, Histochemistry and Cell Biology.

Tumour angiogenesis : basic mechanisms and cancer therapy

N. Fusenig, D. Marmé, 2008 .

Basic fibroblast growth factor modulates the mitogenic potency of the platelet-derived growth factor (PDGF) isoforms by specific upregulation of the PDGF alpha receptor in vascular smooth muscle cells.

J. Folkman, D. Marmé, H. Weich, 1992, The Journal of biological chemistry.

PTK787/ZK 222584, a specific vascular endothelial growth factor-receptor tyrosine kinase inhibitor, affects the anatomy of the tumor vascular bed and the functional vascular properties as detected by dynamic enhanced magnetic resonance imaging.

J. Hennig, J. Wood, J. Drevs, 2002, Cancer research.

Phase I dose escalation, pharmacokinetic (pk) study of a novel vascular endothelial growth factor (VEGF) receptor inhibitor, PTK787/ZK 222584 (PTK/ZK)

J. Drevs, D. Marmé, C. Unger, 1999 .

Angiotensin II mediates intracellular signalling in vascular smooth muscle cells by activation of tyrosine-specific protein kinases and c-raf-1.

D. Marmé, C. Schöllmann, R. Butcher, 1993, Biochemical and biophysical research communications.

Pertussis toxin inhibits angiotensin II-mediated phosphatidylinositol breakdown and ADP-ribosylates a 40 Kd protein in cultured smooth muscle cells.

D. Marmé, P. Gierschik, G. Gaul, 1988, Biochemical and biophysical research communications.

Pertussis toxin inhibits the angiotensin II and serotonin‐induced rise of free cytoplasmic calcium in cultured smooth muscle cells from rat aorta

D. Marmé, C. Bruns, 1987, FEBS letters.

In Vivo and In Vitro Efficacy of an Acid-Sensitive Albumin Conjugate of Adriamycin Compared to the Parent Compound in Murine Renal-Cell Carcinoma

J. Drevs, D. Marmé, C. Unger, 1999 .

Synthetic diacylglycerols induce a rise of quin2‐detectable free intracellular calcium in human platelets

D. Marmé, C. Schächtele, C. Bruns, 1987, FEBS letters.

Identification of a calcium‐ and phospholipid‐dependent protein kinase in plant tissue

D. Marmé, F. Bygrave, A. Schäfer, 1985 .

[Calcium. Molecular mechanisms of cellular function].

D. Marmé, 1985, Die Naturwissenschaften.

Protein Kinase C and Polyphosphoinositide Metabolites: Their Role in Cellular Signal Transduction

D. Marmé, S. Matzenauer, 1985 .

The effect of calmodulin and far-red light on the kinetic properties of the mitochondrial and microsomal calcium-ion transport system from corn

D. Marmé, P. Dieter, 1983, Planta.

Assignment of vascular endothelial growth factor (VEGF) and placenta growth factor (PLGF) genes to human chromosome 6p12-p21 and 14q24-q31 regions, respectively.

D. Birnbaum, M. Mattei, O. Rosnet, 1996, Genomics.

Purification and identification of Calmodulin from Neurospora crassa

J. Cox, D. Marmé, D. van Tuinen, 1981, FEBS letters.

Red Light-enhanced Phytochrome Pelletability: Re-examination and Further Characterization.

D. Marmé, L. Pratt, 1976, Plant physiology.

Particle-bound phytochrome from maize and pumpkin.

P. Quail, E. Schäfer, D. Marmé, 1973, Nature: New biology.

Calmodulin from neurospora crassa. General properties and conformational changes.

J. Cox, C. Ferraz, D. Marmé, 1982, The Journal of biological chemistry.

Raised serum vascular endothelial growth factor levels are associated with destructive change in inflammatory arthritis.

M. Feldmann, D. Marmé, P. Taylor, 2001, Arthritis and rheumatism.

Design, synthesis, and biological evaluation of 3,4-diarylmaleimides as angiogenesis inhibitors.

G. Klebe, R. Brenk, F. Totzke, 2006, Journal of medicinal chemistry.

Calcium, calmodulin‐dependent protein phosphorylation in Neurospora crassa

D. Marmé, D. van Tuinen, G. Turian, 1984 .

Calmodulin-stimulated cyclic nucleotide phosphodiesterase from Neurospora crassa.

D. Marmé, D. van Tuinen, G. Turian, 1983, Biochimica et biophysica acta.

Calcium-binding and its effect on circular dichroism of plant calmodulin

J. Cox, D. Marmé, P. Dieter, 1985, Planta.

Over‐expression of protein kinase C‐α enhances platelet‐derived growth factor‐ and phorbol ester‐ but not calcium ionophore‐induced formation of prostaglandins in NIH 3T3 fibroblasts

F. Totzke, D. Marmé, G. Finkenzeller, 1993, FEBS letters.

Protein kinase C alpha activates RAF-1 by direct phosphorylation.

W. Kolch, G. Kochs, H. Mischak, 1993, Nature.

Proliferation pattern of capillary endothelial cells in chorioallantoic membrane development indicates local growth control, which is counteracted by vascular endothelial growth factor application

D. Marmé, H. Kurz, J. Wilting, 1995, Developmental dynamics : an official publication of the American Association of Anatomists.

AIDS-associated Kaposi's sarcoma cells in culture express vascular endothelial growth factor.

D. Marmé, H. Weich, K. Weindel, 1992, Biochemical and biophysical research communications.

Reversion of deregulated expression of vascular endothelial growth factor in human renal carcinoma cells by von Hippel-Lindau tumor suppressor protein.

G. Martiny-Baron, G. Siemeister, D. Marmé, 1996, Cancer research.

Platelet-derived growth factor-induced transcription of the vascular endothelial growth factor gene is mediated by protein kinase C.

H. Hug, D. Marmé, G. Finkenzeller, 1992, Cancer research.

Herbicides and fungicides inhibit Ca2+ uptake by plant mitochondria: A possible mechanism of action

D. Marmé, C. Hertel, 1983 .

Effects of amiprophosmethyl on massive and limited calcium loading of maize mitochondria.

D. Marmé, H. Affolter, C. Hertel, 1983, The Biochemical journal.

Calmodulin activation of plant microsomal Ca uptake.

D. Marmé, P. Dieter, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Turnover of phytochrome in pumpkin cotyledons.

P. Quail, E. Schäfer, D. Marmé, 1973, Plant physiology.

De novo synthesis of phytochrome in pumpkin hooks.

P. Quail, E. Schäfer, D. Marmé, 1973, Plant physiology.

IN VIVO MEASUREMENTS OF THE PHYTOCHROME PHOTOSTATIONARY STATE IN FAR RED LIGHT

E. Schäfer, D. Marmé, B. Marchal, 1972 .

The isolation and partial characterization of a membrane fraction containing phytochrome.

D. Marmé, J. Mackenzie, W. Briggs, 1974, Plant physiology.

Binding properties in vitro of phytochrome to a membrane fraction.

D. Marmé, W. Briggs, J. Boisard, 1973, Proceedings of the National Academy of Sciences of the United States of America.

APPARENT INCREASE IN PHOTODETECTABLE PHYTOCHROME IN THE PRESENCE OF CALCIUM CARBONATE*

D. Marmé, L. Pratt, B. Gabriac, 1979 .

Phytochrome pelletability in extracts of avena shoots

D. Marmé, W. Rüdiger, L. Pratt, 1975 .

Binding properties of the plant photoreceptor phytochrome to membranes.

D. Marmé, 1974, Journal of supramolecular structure.

EVIDENCE FOR PHYTOCHROME BINDING TO PLASMA MEMBRANE AND ENDOPLASMIC RETICULUM

D. Marmé, J. Gross, J. Bianco, 1976 .

The Isolation and Partial Characterization of a Memnbrane Fraction Containing Phytochromel 2

D. Marmé, J. Mackenzie, W. Briggs, 1974 .

On the localization and orientation of phytochrome molecules in corn coleoptiles (Zea mays L.)

E. Schäfer, D. Marmé, 1972 .

Expression of Angiopoietin-2 in Endothelial Cells Is Controlled by Positive and Negative Regulatory Promoter Elements

H. Augustin, D. Marmé, U. Fiedler, 2004, Arteriosclerosis, thrombosis, and vascular biology.

Oncogenes as inducers of tumor angiogenesis

R. Kerbel, J. Rak, D. Marmé, 1995, Cancer and Metastasis Reviews.

Detection and quantification of vascular endothelial growth factor/vascular permeability factor in brain tumor tissue and cyst fluid: the key to angiogenesis?

J. Moringlane, D. Marmé, H. Weich, 1994, Neurosurgery.

Molecular mechanisms of anti-angiogenic effect of curcumin.

Anupama E. Gururaj, D. Marmé, M. Belakavadi, 2002, Biochemical and biophysical research communications.

The pivotal role of VEGF in tumor angiogenesis: Molecular facts and therapeutic opportunities

G. Martiny-Baron, G. Siemeister, D. Marmé, 1998, Cancer and Metastasis Reviews.

Synthesis and assembly of functionally active human vascular endothelial growth factor homodimers in insect cells.

G. Kochs, B. Fiebich, H. Hug, 1993, European journal of biochemistry.

Subtractive hybridization for differential gene expression in mechanically unloaded rat heart.

D. Marmé, T. Doenst, H. Bugger, 2006, American journal of physiology. Heart and circulatory physiology.

Effects of PTK787/ZK 222584, a specific inhibitor of vascular endothelial growth factor receptor tyrosine kinases, on primary tumor, metastasis, vessel density, and blood flow in a murine renal cell carcinoma model.

G. Martiny-Baron, J. Wood, J. Drevs, 2000, Cancer research.

Expression of the vascular endothelial growth factor gene is inhibited by p73

D. Marmé, G. Finkenzeller, B. Salimath, 2000, Oncogene.

Myosin heavy chain kinase inactivated by Ca2+/calmodulin from aggregating cells of Dictyostelium discoideum.

G. Gerisch, D. Marmé, W. Baltes, 1983, The EMBO journal.

Protein kinase inhibitors: novel tools in cancer therapy

D. Marmé, 2004, Der Urologe.

Two independent mechanisms essential for tumor angiogenesis: inhibition of human melanoma xenograft growth by interfering with either the vascular endothelial growth factor receptor pathway or the Tie-2 pathway.

G. Martiny-Baron, A. Menrad, G. Siemeister, 1999, Cancer research.

Subchloroplastic localization of NAD kinase activity: evidence for a Ca2+, calmodulin‐dependent activity at the envelope and for a Ca2+, calmodulin‐independent activity in the stroma of pea chloroplasts

D. Marmé, H. Greppin, M. Bonzon, 1984 .

The Role of Calcium in the Regulation of Plant Cellular Metabolism

D. Marmé, 1988 .

The Role of Calcium in the Regulation of Plant Metabolism

D. Marmé, 1986 .

Partial purification of plant NAD kinase by calmodulin-Sepharose affinity chromatography

D. Marmé, P. Dieter, 1980 .

Anti-microtubular herbicides and fungicides affect Ca2+ transport in plant mitochondria

D. Marmé, D. Robinson, C. Hertel, 2004, Planta.

Herbicides and fungicides stimulate Ca2+ efflux from rat liver mitochondria

D. Marmé, E. Carafoli, D. Robinson, 1981, FEBS letters.

Ca2+ transport in mitochondrial and microsomal fractions from higher plants

D. Marmé, P. Dieter, 1980, Planta.

ATP-dependent Ca uptake into plant membrane vesicles.

D. Marmé, J. Gross, Joachim Gross, 1978, Proceedings of the National Academy of Sciences of the United States of America.

PTK 787 / ZK 222584 , a Specific Vascular Endothelial Growth Factor-Receptor Tyrosine Kinase Inhibitor , Affects the Anatomy of the Tumor Vascular Bed and the Functional Vascular Properties as Detected by Dynamic Enhanced Magnetic Resonance Imaging 1

J. Hennig, J. Wood, J. Drevs, 2002 .

Effects of PTK 787 / ZK 222584 , a Specific Inhibitor of Vascular Endothelial Growth Factor Receptor Tyrosine Kinases , on Primary Tumor , Metastasis , Vessel Density , and Blood Flow in a Murine Renal Cell Carcinoma Model 1

G. Martiny-Baron, J. Wood, J. Drevs, 2000 .

Regression of Human Breast Carcinoma in Nude Mice after Adsflt Gene Therapy Is Mediated by Tumor Vascular Endothelial Cell Apoptosis

M. Capogrossi, A. Mangoni, D. Marmé, 2020, bioRxiv.

Pathological Angiogenesis: Molecular Aspects and Therapeutic Approaches

D. Marmé, 2004 .

Regulation of the expression of the VEGF/VPS and its receptors: role in tumor angiogenesis

W. Kolch, G. Martiny-Baron, D. Marmé, 2004, Breast Cancer Research and Treatment.

Tumor angiogenesis: the pivotal role of vascular endothelial growth factor

D. Marmé, 2004, World Journal of Urology.

Vascular endothelial growth factor and soluble Tie-2 receptor in colorectal cancer: associations with disease recurrence.

J. Monson, D. Marmé, E. Gardiner, 2003, European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology.

Tumor angiogenesis: molecular facts and therapeutic opportunities

D. Marmé, 1999, Der Chirurg.

An antagonistic vascular endothelial growth factor (VEGF) variant inhibits VEGF-stimulated receptor autophosphorylation and proliferation of human endothelial cells.

G. Martiny-Baron, G. Siemeister, M. Schirner, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1.

A. Mantovani, D. Marmé, S. Sozzani, 1996, Blood.

Vascular endothelial growth factor (VEGF) mRNA expression in human tumor models of different histologies.

R. Mertelsmann, D. Marmé, H. Fiebig, 1995, Annals of oncology : official journal of the European Society for Medical Oncology.

VEGF-mediated tumour angiogenesis: a new target for cancer therapy.

G. Martiny-Baron, D. Marmé, Dieter Marmé, 1995, Current opinion in biotechnology.

Inhibition of Vascular Endothelial Growth Factor Expression in HEC1A Endometrial Cancer Cells through Interactions of Estrogen Receptor α and Sp3 Proteins*

S. Safe, I. Samudio, Fan Wang, 2000, The Journal of Biological Chemistry.

Soluble VEGFR-1 secreted by endothelial cells and monocytes is present in human serum and plasma from healthy donors

F. Totzke, G. Martiny-Baron, D. Marmé, 2004, Angiogenesis.

The α-Helical Domain Near the Amino Terminus Is Essential for Dimerization of Vascular Endothelial Growth Factor*

G. Martiny-Baron, G. Siemeister, D. Marmé, 1998, The Journal of Biological Chemistry.

Mapping of the Sites for Ligand Binding and Receptor Dimerization at the Extracellular Domain of the Vascular Endothelial Growth Factor Receptor FLT-1*

E. Kremmer, F. Totzke, G. Martiny-Baron, 1997, The Journal of Biological Chemistry.

Differential expression of the two VEGF receptors flt and KDR in placenta and vascular endothelial cells

D. Marmé, A. Yayon, S. Hauser, 1994, Journal of cellular biochemistry.

Soluble Tie‐2 receptor levels independently predict locoregional recurrence in head and neck squamous cell carcinoma

J. Drevs, D. Marmé, J. Homer, 2002, Head & neck.

Active interaction of human A375 melanoma cells with the lymphatics in vivo

G. Martiny-Baron, G. Siemeister, D. Marmé, 2000, Histochemistry and Cell Biology.

Sp1 recognition sites in the proximal promoter of the human vascular endothelial growth factor gene are essential for platelet-derived growth factor-induced gene expression

G. Siemeister, D. Marmé, G. Finkenzeller, 1997, Oncogene.

Differentiation and definition of vascular-targeted therapies.

P. LoRusso, A. Dicker, M. Bibby, 2005, Clinical cancer research : an official journal of the American Association for Cancer Research.

Antiangiogenic potency of various chemotherapeutic drugs for metronomic chemotherapy.

J. Drevs, D. Marmé, C. Unger, 2004, Anticancer research.

Advances in Cancer Therapy: Immunotherapies

D. Marmé, 2016, Oncology Research and Treatment.

Sequence of human protein kinase C alpha.

H. Hug, D. Marmé, G. Finkenzeller, 1990, Nucleic acids research.

Identification of a soluble form of the angiopoietin receptor TIE-2 released from endothelial cells and present in human blood

G. Martiny-Baron, G. Siemeister, D. Marmé, 2004, Angiogenesis.

Targeting of endothelial KDR receptors with 3G2 immunoliposomes in vitro.

G. Martiny-Baron, G. Siemeister, D. Marmé, 2000, Biochimica et biophysica acta.

Characterisation of calmodulin from Drosophila heads.

D. Marmé, M. Görlach., C. Kaiser, 1985, Biochimica et biophysica acta.

Specific binding of the calcium antagonist [3H]verapamil to membrane fractions from plants.

R. Hertel, D. Marmé, E. Andrejauskas, 1985, The Journal of biological chemistry.

Both v-Ha-Ras and v-Raf Stimulate Expression of the Vascular Endothelial Growth Factor in NIH 3T3 Cells (*)

D. Marmé, G. Finkenzeller, B. Barleon, 1995, The Journal of Biological Chemistry.

The fungicide chloraniformethan and the herbicide dichlofopmethyl affect calmodulin‐dependent cyclic nucleotide phosphodiesterase from bovine brain

D. Marmé, C. Hertel, Cornelia Hertel, 1983, FEBS letters.

Angiopoietin-1 and Angiopoietin-2 Share the Same Binding Domains in the Tie-2 Receptor Involving the First Ig-like Loop and the Epidermal Growth Factor-like Repeats*

H. Augustin, G. Martiny-Baron, D. Marmé, 2003, The Journal of Biological Chemistry.

Phase I clinical and pharmacokinetic study of PTK/ZK, a multiple VEGF receptor inhibitor, in patients with liver metastases from solid tumours.

Jürgen Hennig, Eric Masson, Yu-Yun Ho, 2005, European journal of cancer.

Activation of purified human protein kinase C alpha and beta I isoenzymes in vitro by Ca2+, phosphatidylinositol and phosphatidylinositol 4,5-bisphosphate.

G. Kochs, B. Fiebich, H. Hug, 1993, The Biochemical journal.

NAD Kinase in Corn: Regulation by Far Red Light is Mediated by Ca2+ and Calmodulin

D. Marmé, P. Dieter, 1986 .

Far-red light irradiation of intact corn seedlings affects mitochondrial and calmodulin-dependent microsomal Ca2+ transport.

D. Marmé, P. Dieter, 1981, Biochemical and biophysical research communications.

The role of calcium and calmodulin in signal transduction

D. Marmé, 1989 .

Protein phosphorylation and its regulation by calcium and calmodulin in membrane fractions from zucchini hypocotyls

D. Marmé, B. Salimath, 1983, Planta.

Activation and substrate specificity of the human protein kinase C alpha and zeta isoenzymes.

G. Kochs, H. Hug, D. Marmé, 1993, European journal of biochemistry.

Stereoselective inhibition of calmodulin-dependent cAMP phosphodiesterase from bovine heart by (+)- and (−)-nimodipine

D. Marmé, C. Schächtele, B. Wagner, 1987, Naunyn-Schmiedeberg's Archives of Pharmacology.

Phorbol 12,13-dibutyrate-induced contraction of isolated rabbit vascular smooth muscle.

D. Marmé, C. Schächtele, B. Wagner, 1987, European journal of pharmacology.

Phosphorylation of the purified receptor for calcium channel blockers by cAMP kinase and protein kinase C.

F. Hofmann, W. Nastainczyk, D. Marmé, 1987, European journal of biochemistry.

Stereospecific inhibition of 5‐HT‐induced increase of intracellular free calcium by (+)‐ and (−)‐desmethoxyverapamil in human platelets

D. Marmé, H. Osswald, C. Bruns, 1986, British Journal of Pharmacology.

Inhibition of tumor growth and angiogenesis by soluble EphB4.

H. Augustin, G. Martiny-Baron, D. Marmé, 2004, Neoplasia.

The impact of anti-angiogenic agents on cancer therapy

D. Marmé, 2003, Journal of Cancer Research and Clinical Oncology.

Activation of plant quinate:NAD 3-oxidoreductase by Ca and calmodulin.

R. Ranjeva, D. Marmé, A. Boudet, 1983, Proceedings of the National Academy of Sciences of the United States of America.

PROTOCHLOROPHYLL(IDE)630 PHOTOSENSITIZES ACTIVE Ca2+ ACCUMULATION IN MICROSOMAL AND MITOCHONDRIAL FRACTIONS ISOLATED FROM PLANTS

D. Marmé, A. Ayadi, J. Gross, 1979 .

A detailed analysis of phytochrome decay and dark reversion in mustard cotyledons

E. Schäfer, D. Marmé, B. Marchal, 1971, Planta.

Tumor Angiogenesis: A Key Target for Cancer Therapy

D. Marmé, 2018, Oncology Research and Treatment.

A Ca2+, Calmodulin-dependent NAD kinase from corn is located in the outer mitochondrial membrane.

D. Marmé, P. Dieter, 1984, The Journal of biological chemistry.

Calmodulin-dependent and independent NAD kinase activities from cytoplasmic and chloroplastic fractions of spinach (Spinacia oleracea L.)

D. Marmé, H. Greppin, P. Dieter, 1982, Plant Cell Reports.

Over‐expression of human phospholipase C‐γ2 enhances platelet‐derived growth factor‐induced mobilization of intracellular Ca2+ and the release of arachidonic acid and prostaglandins in NIH 3T3 fibroblasts

F. Totzke, H. Hug, D. Marmé, 1992, FEBS letters.

Inhibition of tumor growth and angiogenesis by soluble EphB4.

H. Augustin, G. Martiny-Baron, D. Marmé, 2004, Neoplasia.

A Single Local Injection of Recombinant VEGF Receptor 2 But Not of Tie2 Inhibits Retinal Neovascularization in the Mouse

D. Marmé, H. Agostini, U. Fiedler, 2005, Current eye research.

A cAMP-binding phosphoprotein in Drosophila heads is similar to the regulatory subunit of the mammalian type II cAMP-dependent protein kinase

D. Marmé, J. Hesse, 1985 .

Microsomal CA2+ uptake in human platelets is stimulated by calmodulin.

D. Marmé, E. Mittelholzer, R. Muggli, 1986, Thrombosis research.

Vascular endothelial growth factor in the sera and effusions of patients with malignant and nonmalignant disease

D. Marmé, C. Unger, C. Marth, 1999, Cancer.

Lack of an effect of novel inhibitors with high specificity for protein kinase C on the action of the phorbol ester 12-O-tetradecanoylphorbol-13-acetate on mouse skin in vivo.

D. Marmé, C. Schächtele, M. Gschwendt, 1995, Carcinogenesis.

Overexpression of PKCε in R6 fibroblasts causes increased production of active TGFβ

A. Cacace, I. Weinstein, D. Marmé, 1998, Journal of cellular physiology.

PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration.

J. Mestan, F. Totzke, G. Martiny-Baron, 2000, Cancer research.

Plasmalemma and tonoplast : their functions in the plant cell : proceedings of the International Workshop on Plasmalemma and Tonoplast of Plant Cells held in Strasbourg, France, September 8-11, 1981

R. Hertel, D. Marmé, E. Marrè, 1982 .

Differential Gene Expression in Response to Ventricular Unloading in Rat and Human Myocardium

D. Marmé, F. Beyersdorf, T. Doenst, 2005, The Thoracic and cardiovascular surgeon.

Calcium

D. Marmé, 1985, Naturwissenschaften.

Implications of Vascular Endothelial Growth Factor, sFlt-1, and sTie-2 in Plasma, Serum and Cerebrospinal Fluid during Cerebral Ischemia in Man

J. Zentner, J. Drevs, D. Marmé, 2003, Journal of Cerebral Blood Flow and Metabolism.

An endogenous membrane-bound protein inhibits the phosphorylation of the L-type calcium channel by the cAMP-dependent protein kinase.

R. Woscholski, D. Marmé, 1992, Biochemical and biophysical research communications.

Dihydropyridine binding of the calcium channel complex from skeletal muscle is modulated by subunit interaction.

R. Woscholski, D. Marmé, 1992, Cellular signalling.