D. Meijer

H. Schuitemaker, E. De Clercq, R. Pauwels, 1996, Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association.

The sinusoidal efflux of dibromosulfophthalein from rat liver is stimulated by albumin, ligandin and fatty acid binding protein but not by other dibromosulfophthalein binding proteins.

J. Proost, G. Groothuis, D. Meijer, 1994, Journal of hepatology.

Influence of albumin on the net sinusoidal efflux of the organic anion dibromosulfophthalein from rat liver

G. Groothuis, D. Meijer, T. Pijning, 1992, Hepatology.

Collection of metabolites in bile and urine from the rat.

G. Mulder, D. Meijer, E. Scholtens, 1981, Methods in enzymology.

Isolated perfused liver as a tool to study the disposition of peptides, liver first-pass effects, and cell-specific drug delivery

D. Meijer, P. Swart, 1997 .

Interactions of cationic drugs and cardiac glycosides at the hepatic uptake level: studies in the ratin vivo, isolated perfused rat liver, isolated rat hepatocytes and oocytes expressing oatp2

D. Meijer, J. V. van Montfoort, 2002, Archives of pharmacal research.

Isolated perfused rat liver technique.

G. Mulder, D. Meijer, K. Keulemans, 1981, Methods in enzymology.

Molecular Mechanisms of the Adsorption of a Model Protein (Human Serum Albumin) on Poly(Methylidene Malonate 2.1.2) Nanoparticles

D. Meijer, J. Hoebeke, P. J. Swart, 2004, Pharmaceutical Research.

REDUCTASE INHIBITORS INDUCE HEPATIC EXPRESSION OF THE PHOSPHOLIPID TRANSLOCASE MDR2 P-GLYCOPROTEIN IN RATS

G. Hooiveld, D. Meijer, V. Bloks, 2000 .

University of Groningen 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors ( statins ) induce hepatic expression of the phospholipid translocase mdr 2 in rats

G. Hooiveld, D. Meijer, P. Jansen, 1999 .

3-Hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors (statins) induce hepatic expression of the phospholipid translocase mdr2 in rats.

G. Hooiveld, D. Meijer, H. van Goor, 1999, Gastroenterology.

Biliary excretion of FITC metabolites after administration of FITC labeled asialo orosomucoid as a measure of lysosomal proteolysis.

D. Meijer, P. van der Sluijs, J. G. Weitering, 1985, Biochemical pharmacology.

Pharmacokinetic and Biodistribution Profile of Recombinant Human Interleukin-10 Following Intravenous Administration in Rats with Extensive Liver Fibrosis

D. Meijer, H. Rachmawati, W. Hagens, 2004, Pharmaceutical Research.

Cell-specific Delivery of a Transforming Growth Factor-beta Type I Receptor Kinase Inhibitor to Proximal Tubular Cells for the Treatment of Renal Fibrosis

R. Kok, D. Meijer, M. Borst, 2008, Pharmaceutical Research.

Preparation and characterization of conjugates of (modified) human serum albumin and liposomes: drug carriers with an intrinsic anti-HIV activity.

E. De Clercq, R. Pauwels, D. Meijer, 1996, Biochimica et biophysica acta.

Transport of organic cations by the rat organic anion transporting polypeptides oatp1, oatp2 and the human OATP.

P. Meier, D. Meijer, B. Hagenbuch, 1998 .

Influence of bile salts on hepatic transport of dibromosulphthalein.

M. Danhof, D. Meijer, R. Vonk, 1979, The American journal of physiology.

Carrier-mediated transport in the hepatic distribution and elimination of drugs, with special reference to the category of organic cations

D. Meijer, Michael Müller, G. Kurz, 1990, Journal of Pharmacokinetics and Biopharmaceutics.

Heterogeneous acinar localization of the asialoglycoprotein internalization system in rat hepatocytes

P. Sluijs, G. Groothuis, D. Meijer, 1988, Hepatology.

Heterogeneity of rat hepatocytes in transport and hepatic binding of asialoalkaline phosphatase studied after induction of selective acinar damage by N-hydroxy-2-acetylaminofluorene and carbon tetrachloride.

D. Meijer, J. G. Weitering, M. Hardonk, 1983, Biochemical pharmacology.

A physiologic function for alkaline phosphatase: endotoxin detoxification.

D. Meijer, D. Meijer, K. Poelstra, 1997, Laboratory investigation; a journal of technical methods and pathology.

Targeting dexamethasone to Kupffer cells: Effects on liver inflammation and fibrosis in rats

P. Olinga, D. Schuppan, G. Groothuis, 2001, Hepatology.

Synergistic Fungistatic Effects of Lactoferrin in Combination with Antifungal Drugs against ClinicalCandida Isolates

D. Meijer, M. C. Eikelboom, M. Kuipers, 1999, Antimicrobial Agents and Chemotherapy.

Drug targeting to the liver with lactosylated albumins: Does the glycoprotein target the drug or is the drug targeting the glycoprotein?

D. Meijer, P. van der Sluijs, F. Moolenaar, 1986, Hepatology.

Drug Targeting with Glycoproteins and Other Peptide Carriers: An Overview

D. Meijer, 1994 .

Structure-pharmacokinetics relationship of series of aminosteroidal neuromuscular blocking agents in the cat.

J. Proost, D. Meijer, D. Meijer, 2000, The Journal of pharmacology and experimental therapeutics.

Bioanalysis and pharmacokinetics of the p38 MAPkinase inhibitor SB202190 in rats.

R. Kok, D. Meijer, J. Prakash, 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Endothelial cells internalize and degrade RGD-modified proteins developed for tumor vasculature targeting.

G. Molema, H. Moorlag, R. Kok, 2002, Journal of controlled release : official journal of the Controlled Release Society.

Inhibition of cytomegalovirus infection by lactoferrin in vitro and in vivo.

M. Harmsen, G. Molema, D. Meijer, 2004, Antiviral research.

Conditions influencing the in vitro antifungal activity of lactoferrin combined with antimycotics against clinical isolates of Candida

D. Meijer, J. J. van den Berg, M. Kuipers, 2002, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

Viral Load in Breast Milk Correlates with Transmission of Human Cytomegalovirus to Preterm Neonates, but Lactoferrin Concentrations Do Not

D. Meijer, G. Jahn, T. The, 2001, Clinical Diagnostic Laboratory Immunology.

ADVANCES IN LACTOFERRIN RESEARCH

D. Meijer, M. Harmsen, P. J. Swart, 1998 .

Antiviral effects of milk proteins: acylation results in polyanionic compounds with potent activity against human immunodeficiency virus types 1 and 2 in vitro.

E. De Clercq, R. Pauwels, D. Meijer, 1996, AIDS research and human retroviruses.

(Glyco)-protein drug carriers with an intrinsic therapeutic activity : The concept of dual targeting

D. Zeeuw, G. Molema, D. Meijer, 1996 .

Antiviral effects of milk proteins: Acylation results in polyanionic compounds with potent activity against HIV type I and II in vitro

D. Meijer, M. Kuipers, P. J. Swart, 1996 .

Antiviral effects of plasma and milk proteins: lactoferrin shows potent activity against both human immunodeficiency virus and human cytomegalovirus replication in vitro.

E. De Clercq, R. Pauwels, D. Meijer, 1995, The Journal of infectious diseases.

Mechanisms for the Hepatic Clearance of Oligopeptides and Proteins

D. Meijer, K. Ziegler, 1993 .

Neoglycoproteins as carriers for antiviral drugs: synthesis and analysis of protein-drug conjugates.

P. Herdewijn, G. Molema, D. Meijer, 1991, Journal of medicinal chemistry.

Preparation and Functional Evaluation of RGD-Modified Proteins as r v â 3 Integrin Directed Therapeutics

G. Molema, H. Moorlag, M. Everts, 2022 .

Renal targeting of captopril selectively enhances the intrarenal over the systemic effects of ACE inhibition in rats

G. Navis, D. de Zeeuw, D. Meijer, 2003, British journal of pharmacology.

Renal targeting of captopril selectively enhances the intrarenal over the systemic effects of ACE inhibition in rats

G. Navis, D. Meijer, D. Zeeuw, 2002, British Journal of Pharmacology.

Drug targeting to the kidney with low-molecular-weight proteins

D. Meijer, D. Zeeuw, F. Moolenaar, 1994 .

Effects of anti-proteinuric therapy with angiotensin-converting-enzyme inhibition on renal protein catabolism in the adriamycin-induced nephrotic rat.

D. de Zeeuw, D. Meijer, P. D. de Jong, 2003, Clinical science.

and activated hepatic stellate cells IL-10 receptor and coreceptor expression in quiescent

P. Olinga, S. Friedman, A. L. Draaisma, 2005 .

Selective targeting of pentoxifylline to hepatic stellate cells using a novel platinum-based linker technology.

G. Molema, R. Kok, D. Meijer, 2006, Journal of controlled release : official journal of the Controlled Release Society.

Localization of d-tubocurarine in rat liver lysosomes

G. Mulder, D. Meijer, J. G. Weitering, 1977, Naunyn-Schmiedeberg's Archives of Pharmacology.

Resistance of the human immunodeficiency virus to the inhibitory action of negatively charged albumins on virus binding to CD4.

E. De Clercq, B. Clotet, D. Meijer, 1999, AIDS research and human retroviruses.

Removal of Phosphate from Lipid A as a Strategy to Detoxify Lipopolysaccharide

D. Meijer, K. Poelstra, W. Verweij, 2002, Shock.

Dephosphorylation of endotoxin by alkaline phosphatase in vivo.

D. Meijer, J. Kamps, D. Meijer, 1997, The American journal of pathology.

Inhibition of renal rho kinase attenuates ischemia/reperfusion-induced injury.

R. Kok, D. Meijer, H. van Goor, 2008, Journal of the American Society of Nephrology : JASN.

RGD‐modified anti‐CD3 antibodies redirect cytolytic capacity of cytotoxic T lymphocytes toward αvβ3‐expressing endothelial cells

S. Withoff, G. Molema, R. Kok, 2004 .

Autoradiographic and kinetic demonstration of acinar heterogeneity of taurocholate transport.

D. Meijer, P. Nieuwenhuis, M. Hardonk, 1982, The American journal of physiology.

The Pharmacokinetic and Biological Activity Profile of Dexamethasone Targeted to Sinusoidal Endothelial and Kupffer Cells

D. Meijer, H. Schellekens, B. Melgert, 2003, Journal of drug targeting.

Interaction of targeted liposomes with primary cultured hepatic stellate cells: Involvement of multiple receptor systems.

J. Kamps, G. Molema, D. Meijer, 2006, Journal of hepatology.

Massive and Selective Delivery of Lipid-Coated Cationic Lipoplexes of Oligonucleotides Targeted in Vivo to Hepatic Endothelial Cells

J. Kamps, D. Meijer, G. Scherphof, 2002, Pharmaceutical Research.

A histochemical study on the distribution of injected canine intestinal alkaline phosphatase in rat liver.

D. Meijer, M. Hardonk, H. B. Scholtens, 2008, Liver.

Choleresis and hepatic transport mechanisms

P. Jekel, D. Meijer, R. Vonk, 2004, Naunyn-Schmiedeberg's Archives of Pharmacology.

The influence of taurocholate and dehydrocholate choleresis on plasma disappearance and biliary excretion of indocyanine green in the rat

D. Meijer, R. Vonk, H. Veen, 2004, Naunyn-Schmiedeberg's Archives of Pharmacology.

Secretion of the organic anion harmol sulfate from liver into blood. Evidence for a carrier-mediated mechanism.

G. Mulder, D. Meijer, M. de Vries, 1985, Biochemical pharmacology.

Potent inhibition of replication of primary HIV type 1 isolates in peripheral blood lymphocytes by negatively charged human serum albumins.

H. Schuitemaker, D. Meijer, M. Kuipers, 1997, AIDS research and human retroviruses.

Preparation and functional evaluation of RGD-modified proteins as alpha(v)beta(3) integrin directed therapeutics.

Grietje Molema, G. Molema, H. Moorlag, 2002, Bioconjugate chemistry.

Heterogeneity of rat hepatocytes in bile acid and DBSP transport studied after induction of selective acinar damage by N-hydroxy-2-acetylaminofluorene and carbon tetrachloride

G. Groothuis, D. Meijer, J. G. Weitering, 1983, Naunyn-Schmiedeberg's Archives of Pharmacology.

Formation of a metabolite of dibromosulfophthalein (DBSP) in man

D. Meijer, N. Javitt, J. G. Weitering, 2004, European Journal of Clinical Pharmacology.

Acinar heterogeneity in hepatic transport of dibromosulfophthalein and ouabain studied by autoradiography, normal and retrograde perfusions and computer simulation.

D. Meijer, M. Hardonk, G. Groothuis, 1983, Biochemical pharmacology.

The influence of various bile salts and some cholephilic dyes on Na+- and Mg2+-activated ATPase of rat liver in relation to cholestatic effects.

D. Meijer, R. Vonk, J. G. Weitering, 1978, Toxicology and applied pharmacology.

Function and regulation of ATP-binding cassette transport proteins involved in hepatobiliary transport (vol 12, pg 13, 2000)

D. Meijer, G. Hooiveld, J. V. Montfoort, 2001 .

RENAL-SELECTIVE DELIVERY AND ANGIOTENSIN-CONVERTING ENZYME INHIBITION BY SUBCUTANEOUSLY ADMINISTERED CAPTOPRIL-LYSOZYME

J. Proost, R. Kok, D. Meijer, 2005, Drug Metabolism and Disposition.

Targeting of Drugs to the Liver

G. Molema, D. Meijer, 1995, Seminars in liver disease.

Renal drug delivery with low-molecular-weight proteins : The effect of charge modifications on the body distribution of drug-lysozyme conjugates

D. Zeeuw, R. Kok, D. Meijer, 1999 .

Massive targeting of liposomes, surface-modified with anionized albumins, to hepatic endothelial cells.

J. Kamps, D. Meijer, H. Morselt, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Prediction of the pharmacokinetics of succinylated human serum albumin in man from in vivo disposition data in animals and in vitro liver slice incubations.

P. Olinga, J. Proost, G. Groothuis, 2006, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Pharmacokinetics of xamoterol glucuronidation in the rat in vivo and in liver perfusion.

G. Mulder, D. Meijer, K. Groen, 1987, Xenobiotica; the fate of foreign compounds in biological systems.

Targeting of Doxorubicin to the Urinary Bladder of the Rat Shows Increased Cytotoxicity in the Bladder Urine Combined With An Absence of Renal Toxicity

D. Meijer, D. Zeeuw, P. D. Jong, 2002, Journal of drug targeting.

Pharmacokinetic Analysis and Cellular Distribution of the Anti-HIV Compound Succinylated Human Serum Albumin (Suc-HSA) in Vivo and in the Isolated Perfused Rat Liver

P. Olinga, D. Meijer, G. Harms, 1993, Pharmaceutical Research.

Abstracts of papers Rational use of drugs

L. L. Rodriguez, C. Torras, G. Raskob, 1989, Pharmaceutisch Weekblad.

Separation of periportal and perivenous rat hepatocytes by fluorescence‐activated cell sorting: Confirmation with colloidal gold as an exogenous marker

G. Groothuis, D. Meijer, I. Braakman, 1991, Hepatology.

Studies on the targeted delivery of the antifibrogenic compound mycophenolic acid to the hepatic stellate cell.

R. Kok, D. Meijer, H. Bakker, 2005, Journal of hepatology.

Albumin modified with mannose 6‐phosphate: A potential carrier for selective delivery of antifibrotic drugs to rat and human hepatic stellate cells

P. Olinga, G. Groothuis, G. Molema, 1999, Hepatology.

Targeting of sugar- and charge-modified albumins to fibrotic rat livers: the accessibility of hepatic cells after chronic bile duct ligation.

G. Molema, D. Meijer, L. Beljaars, 1998, Journal of hepatology.

The influence of pH on rectal absorption of sodium benzoate studied in man by rectal lumen perfusion

D. Meijer, A. Schoonen, J. Visser, 1990, Journal of Pharmacokinetics and Biopharmaceutics.

Distribution of quaternary ammonium compounds between particulate and soluble constituents of rat liver, in relation to their transport from plasma into bile

D. Meijer, J. Wester, M. Gunnink, 2004, Naunyn-Schmiedeberg's Archives of Pharmacology.

Hepatic transport mechanisms for bivalent organic cations. Subcellular distribution and hepato-biliary concentration gradients of some steroidal muscle relaxants.

W. E. Mol, D. Meijer, W. Mol, 1990, Biochemical pharmacology.

The influence of charge clustering on the anti-HIV-1 activity and in vivo distribution of negatively charged albumins.

B. Berkhout, G. Molema, D. Meijer, 2002, Biochemical pharmacology.

The Metabolic Fate of the Anti-HIV Active Drug Carrier Succinylated Human Serum Albumin after Intravenous Administration in Rats

D. Meijer, M. Kuipers, P. J. Swart, 2001, Journal of drug targeting.

Pharmacokinetics and anti-HIV-1 efficacy of negatively charged human serum albumins in mice.

J. Proost, D. Meijer, M. Schutten, 1997, Antiviral research.

Choleresis and hepatic transport mechanisms

D. Meijer, R. Vonk, E. Scholtens, 1978, Naunyn-Schmiedeberg's Archives of Pharmacology.

Hepatic transport of mono and bisquaternary ammonium compounds

D. Meijer, E. Bos, K. V. Laan, 1970 .

Exploring the regulation of endogenous alkaline phosphatase levels

D. Meijer, K. Poelstra, 2007 .

Dissemination of Rat Cytomegalovirus through Infected Granulocytes and Monocytes In Vitro and In Vivo

M. Harmsen, G. Molema, D. Meijer, 2003, Journal of Virology.

Mechanism of anti-HIV activity of succinylated human serum albumin.

D. Meijer, J. Laman, M. Kuipers, 1999, Biochemical pharmacology.

Determination of the membrane potential in bacterial membrane vesicles from the accumulation of N‐methyldeptropine

W. Konings, D. Meijer, P. G. Ruifrok, 1979, FEBS letters.

Oral Presentations—Abstracts

A. Eggermont, K. Edwards, A. Chanan-Khan, 2003, Turkish Journal of Biochemistry.

Hepatic uptake and biliary excretion of d-tubocurarine and trimethyltubocurarine in the rat in vivo and in isolated perfused rat livers.

D. Meijer, R. Vonk, J. G. Weitering, 1976, The Journal of pharmacology and experimental therapeutics.

Formation of a metabolite of dibromosulfophthalein (DBSP) in man

D. Meijer, J. G. Weitering, B. Bajema, 2004, European Journal of Clinical Pharmacology.

Abstracts of papers

J. Greve, J. G. McVie, G. L. Scherphof, 2005, Pharmaceutisch Weekblad.

Dexamethasone coupled to albumin is selectively taken up by rat nonparenchymal liver cells and attenuates LPS-induced activation of hepatic cells.

P. Olinga, G. Molema, D. Meijer, 2000, Journal of hepatology.

The Effects of Cyclodextrins on the Disposition of Intravenously Injected Drugs in the Rat

A. C. Eissens, H. Frijlink, D. Meijer, 1991, Pharmaceutical Research.

Chiral Differences in the Disposition of the Quaternary Anticholinergic Drug Oxyphenonium Bromide

R. A. Zeeuw, D. Meijer, K. G. Feitsma, 1988 .

Antispasmodic effects of valeriana compounds: an in-vivo and in-vitro study on the guinea-pig ileum.

D. Meijer, B. Hazelhoff, T. Malingré, 1982, Archives internationales de pharmacodynamie et de therapie.

Stereoselective transport of hydrophilic quaternary drugs by human MDR1 and rat Mdr1b P‐glycoproteins

G. Hooiveld, D. Meijer, P. Jansen, 2002, British journal of pharmacology.

Drug Targeting: Organ-Specific Strategies

Grietje Molema, G. Molema, D. Meijer, 2001 .

Design and Fungicidal Activity of Mucoadhesive Lactoferrin Tablets for the Treatment of Oropharyngeal Candidosis

D. Meijer, H. Bakker, P. J. Swart, 2002, Drug delivery.

Bioanalysis of captopril: two sensitive high-performance liquid chromatographic methods with pre- or postcolumn fluorescent labeling.

D. de Zeeuw, R. Kok, D. Meijer, 1997, Journal of chromatography. B, Biomedical sciences and applications.

Distribution and Elimination of the Glycosidase Inhibitors 1-Deoxymannojirimycin and N-Methyl-1-Deoxynojirimycin in the Rat in Vivo

H. Ploegh, J. Neefjes, D. Meijer, 1992, Pharmaceutical Research.

Disposition of Glycosidase Inhibitors in the Isolated Perfused Rat Liver: Hepatobiliary and Subcellular Concentration Gradients of 1-Deoxymannojirimycin and N-Methyl-1-Deoxynojirimycin

J. Proost, D. Meijer, R. Oosting, 2004, Pharmaceutical Research.

Structure-pharmacokinetics relationship of quaternary ammonium compounds

D. Meijer, C. Neef, 1984, Naunyn-Schmiedeberg's Archives of Pharmacology.

Structure-pharmacokinetics relationship of quaternary ammonium compounds

D. Meijer, C. Neef, R. Oosting, 1984, Naunyn-Schmiedeberg's Archives of Pharmacology.

The role of the liver in clearance of glycoproteins from the general circulation, with special reference to intestinal alkaline phosphatase

D. Meijer, D. Meijer, M. Hardonk, 1982, Pharmaceutisch Weekblad.

A kinetic study of hepatic uptake of canine intestinal alkaline phosphatase in the rat.

D. Meijer, M. Hardonk, H. B. Scholtens, 2008, Liver.

On the role and fate of LPS-dephosphorylating activity in the rat liver.

D. Meijer, A. Huizinga-van der Vlag, K. Poelstra, 2006, American journal of physiology. Gastrointestinal and liver physiology.

Liver slices in in vitro pharmacotoxicology with special reference to the use of human liver tissue.

P. Olinga, G. Groothuis, D. Meijer, 1997, Toxicology in vitro : an international journal published in association with BIBRA.

The in vitro anti-HIV efficacy of negatively charged human serum albumin is antagonized by heparin.

D. Meijer, S. Josephs, M. Kuipers, 1997, AIDS research and human retroviruses.

Formaldehyde treated albumin contains monomeric and polymeric forms that are differently cleared by endothelial and Kupffer cells of the liver: evidence for scavenger receptor heterogeneity.

G. Molema, D. Meijer, T. V. van Berkel, 1991, Biochemical and biophysical research communications.

Sequestration of organic cations by acidified hepatic endocytic vesicles and implications for biliary excretion.

D. Meijer, R. V. Van Dyke, E. D. Faber, 1992, The Journal of pharmacology and experimental therapeutics.

Hepatic uptake and biliary excretion of organic cations--I. Characterization of three new model compounds.

D. Meijer, C. Neef, K. Keulemans, 1984, Biochemical pharmacology.

Hepatic drug transport in the rat. A comparison between isolated hepatocytes, the isolated perfused liver and the liver in vivo.

D. Meijer, A. Scaf, A. Blom, 1982, Biochemical pharmacology.

HEPATIC TRANSPORT OF ORGANIC CATIONS - INFLUENCE OF BILE-SALT CHOLERESIS

D. Meijer, R. Vonk, K. Keulemans, 1906 .

Mrp2 is essential for estradiol‐17β(β‐D ‐glucuronide)–induced cholestasis in rats

D. Meijer, J. Smit, Liyue Huang, 2000 .

Mrp2 is essential for estradiol-17beta(beta-D-glucuronide)-induced cholestasis in rats.

D. Meijer, L. Huang, J. Smit, 2000, Hepatology.

TARGETING OF DRUGS TO VARIOUS BLOOD-CELL TYPES USING (NEO-)GLYCOPROTEINS, ANTIBODIES AND OTHER PROTEIN CARRIERS

G. Molema, D. Meijer, 1994 .

Targeting of antiviral drugs to T4-lymphocytes. Anti-HIV activity of neoglycoprotein-AZTMP conjugates in vitro.

E. De Clercq, R. Pauwels, G. Molema, 1990, Biochemical pharmacology.

The N-benzyl derivative of the glucosidase inhibitor 1-deoxynojirimycin shows a prolonged half-life and a more complete oral absorption in the rat compared with the N-methyl analog.

D. Meijer, L. V. D. van den Broek, E. D. Faber, 1998, Drug delivery.

Hepatobiliary elimination of cationic drugs: The role of P-glycoproteins and other ATP-dependent transporters

D. Meijer, J. Smit, Michael Müller, 1997 .

Binding of drugs with a quaternary ammonium group to alpha-1 acid glycoprotein and asialo alpha-1 acid glycoprotein.

D. Meijer, P. van der Sluijs, 1985, The Journal of pharmacology and experimental therapeutics.

Cell-Specific Targeting of Lipid-Based Carriers for ODN and DNA

J. Kamps, D. Meijer, G. Scherphof, 2005, Journal of liposome research.

Characteristics of the hepatic stellate cell-selective carrier mannose 6-phosphate modified albumin (M6P(28)-HSA).

P. Olinga, G. Groothuis, P. de Bleser, 2001, Liver.

Hepatobiliary and intestinal clearance of amphiphilic cationic drugs in mice in which both mdr1a and mdr1b genes have been disrupted

D. Meijer, A. Schinkel, J. Smit, 1998, British journal of pharmacology.

Contribution of the murine mdr1a P‐glycoprotein to hepatobiliary and intestinal elimination of cationic drugs as measured in mice with an mdr1a gene disruption

D. Meijer, A. Schinkel, J. Smit, 1998, Hepatology.

Clearance of indometacin occurs predominantly by renal glucuronidation

D. Meijer, D. Zeeuw, F. Moolenaar, 1992, Pharmaceutisch Weekblad.

Simultaneous analysis of azidothymidine and its mono-, di- and triphosphate derivatives in biological fluids, tissue and cultured cells by a rapid high-performance liquid chromatographic method.

G. Molema, D. Meijer, R. Jansen, 1992, Journal of chromatography.

Localization of organic anion transporting polypeptide 4 (Oatp4) in rat liver and comparison of its substrate specificity with Oatp1, Oatp2 and Oatp3

P. Meier, D. Meijer, B. Stieger, 2001, Pflügers Archiv.

POTENTIALS AND LIMITATIONS OF THE LOW-MOLECULAR-WEIGHT PROTEIN LYSOZYME AS A CARRIER FOR RENAL DRUG TARGETING

D. de Zeeuw, D. Meijer, P. M. deVries, 2001, Renal failure.

Pharmacokinetics and In Vivo Gene Transfer of Plasmid DNA Complexed with Mannosylated Poly(L-Lysine) in Mice

M. Hashida, F. Yamashita, D. Meijer, 2000, Journal of drug targeting.

Liver fibrosis in vitro: cell culture models and precision-cut liver slices.

P. Olinga, G. Groothuis, D. Meijer, 2007, Toxicology in vitro : an international journal published in association with BIBRA.

Potent in vitro anti-human immunodeficiency virus-1 activity of modified human serum albumins.

E. De Clercq, R. Pauwels, G. Molema, 1991, Molecular pharmacology.

CLONING OF THE CDNA ENCODING THE RAT MULTIDRUG RESISTANCE ( MDR ) 1 A P-GLYCOPROTEIN

G. Hooiveld, D. Meijer, P. Jansen, 2000 .

Function and regulation of ATP-binding cassette transport proteins involved in hepatobiliary transport.

G. Hooiveld, D. Meijer, M. Müller, 2001, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

The molecular basis for hepatobiliary transport of organic cations and organic anions.

G. Hooiveld, D. Meijer, P. Jansen, 1999, Pharmaceutical biotechnology.

Concentrations Do Not to Preterm Neonates , but Lactoferrin Transmission of Human Cytomegalovirus Viral Load in Breast Milk Correlates with

M. Harmsen, D. Meijer, G. Jahn, 2001 .

Targeting hepatic stellate cells for cell-specific treatment of liver fibrosis.

Klaas Poelstra, Leonie Beljaars, D. Meijer, 2002, Frontiers in bioscience : a journal and virtual library.

Interactions between P‐glycoprotein substrates and other cationic drugs at the hepatic excretory level

D. Meijer, J. Smit, R. Oosting, 1998, British journal of pharmacology.

Characterization of transport in isolated human hepatocytes. A study with the bile acid taurocholic acid, the uncharged ouabain and the organic cations vecuronium and rocuronium.

P. Olinga, G. Groothuis, D. Meijer, 1994, Biochemical pharmacology.

An extended pharmacokinetic/pharmacodynamic model describing quantitatively the influence of plasma protein binding, tissue binding, and receptor binding on the potency and time course of action of drugs

J. Proost, J. Wierda, D. Meijer, 1996, Journal of Pharmacokinetics and Biopharmaceutics.

The Fate of Pancuronium Bromide in Man

D. Meijer, S. Ágoston, G. Vermeer, 1973, Acta anaesthesiologica Scandinavica.

The Fate of Pancuronium Bromide in the Cat

D. Meijer, S. Ágoston, U. W. Kersten, 1973, Acta anaesthesiologica Scandinavica.

Mechanisms underlying the prolonged duration of action of muscle relaxants caused by extrahepatic cholestasis.

D. Meijer, M. Houwertjes, M. J. Hardonk, 1981, British journal of anaesthesia.

Comparative Pharmacokinetics of d‐Tubocurarine and Metocurine in Man

D. Meijer, A. Scaf, G. Vermeer, 1979, Anesthesiology.

Uptake and Excretion of Vecuronium Bromide and Pancuronium Bromide in the Isolated Perfused Rat Liver

D. Meijer, A. Scaf, S. Ágoston, 1988, Anesthesiology.

Fluorimetric and chromatographic determination of pancuronium bromide and its metabolites in biological materials.

D. Meijer, S. Ágoston, U. W. Kersten, 1973, Clinica chimica acta; international journal of clinical chemistry.

A pharmacokinetic/pharmacodynamic model explaining the altered potency and time course of action of neuromuscular blocking agents in myasthenic patients

J. Proost, D. Meijer, J. Wierda, 1997 .

Comparative pharmacokinetics of d-tubocurarine and metocurine in man.

D. Meijer, J. G. Weitering, A. Scaf, 1979 .

Pharmacokinetics of steroidal muscle relaxants in isolated perfused rat liver.

W. E. Mol, D. Meijer, F. Rombout, 1992, Biochemical pharmacology.

Pharmacokinetics of biliary excretion in man V

D. Meijer, D. K. F. Meijer, J. G. Weitering, 1983, European Journal of Clinical Pharmacology.

Effect of Hypothermia on the Hepatic Uptake and Biliary Excretion of Vecuronium in the Isolated Perfused Rat Liver

J. Proost, J. Maring, J. Wierda, 2001, Anesthesiology.

Bile salts and neuromuscular blocking agents.

D. Meijer, M. Houwertjes, P. Westra, 1981, British journal of anaesthesia.

Relationship between Chemical Structure and Physicochemical Properties of Series of Bulky Organic Cations and Their Hepatic Uptake and Biliary Excretion Rates 1

J. Proost, J. Wierda, D. Meijer, 1997 .

Preliminary study on the absorption profile after rectal and oral administration of methadone in human volunteers

D. Meijer, F. Moolenaar, J. Visser, 1984, Pharmaceutisch Weekblad.

Drastic improvement in the rectal absorption profile of morphine in man

D. Meijer, J. Yska, F. Moolenaar, 2004, European Journal of Clinical Pharmacology.

The excretion of hexafluorenium in man and rat.

G. Kwant, D. Meijer, G. Vermeer, 1971, European journal of pharmacology.

Curare-like agents: relation between lipid solubility and transport into bile in perfused rat liver.

D. Meijer, J. G. Weitering, 1970, European journal of pharmacology.

MDR2 GENE EXPRESSION BY CHOLESTEROL SYNTHESIS INHIBITORS AND STEROL REGULATORY ELEMENT-BINDING PROTEINS

G. Hooiveld, D. Meijer, P. Jansen, 2000 .

TRANSCRIPTIONAL REGULATION OF THE RAT PHOSPHOLIPID TRANSLOCASE MDR 2 GENE EXPRESSION BY CHOLESTEROL SYNTHESIS INHIBITORS AND STEROL REGULATORY ELEMENT-BINDING PROTEINS

G. Hooiveld, D. Meijer, P. Jansen, 2000 .

Value of the in vitro or in vivo monoethylglycinexylidide test for predicting liver graft function.

P. Olinga, G. Groothuis, D. Meijer, 1997, Transplantation.

Characterization of the uptake of rocuronium and digoxin in human hepatocytes: carrier specificity and comparison with in vivo data.

P. Olinga, J. Proost, G. Groothuis, 1998, The Journal of pharmacology and experimental therapeutics.

Hepatobiliary transport of drugs: do periportal and perivenous hepatocytes perform the same job?

G. Groothuis, D. Meijer, M. J. Hardonk, 1985 .

CORRELATION BETWEEN PHYSICO-CHEMICAL PROPERTIES AND PHARMACOKINETIC AND DYNAMIC PARAMETERS OF MUSCLE RELAXANTS

J. Proost, J. Wierda, D. Meijer, 1992 .

Metabolism of three pharmacologically active drugs in isolated human and rat hepatocytes: analysis of interspecies variability and comparison with metabolism in vivo.

G. Groothuis, D. Meijer, L. Delbressine, 1994, Xenobiotica; the fate of foreign compounds in biological systems.

Polyspecific organic anion transporting polypeptides mediate hepatic uptake of amphipathic type II organic cations.

G. Groothuis, P. Meier, D. Meijer, 1999, The Journal of pharmacology and experimental therapeutics.

Hepatic disposition of cationic drugs bound to asialoorosomucoid: lack of coendocytosis and evidence for intrahepatic dissociation.

D. Meijer, P. van der Sluijs, H. Spanjer, 1987, The Journal of pharmacology and experimental therapeutics.

Transport of dibromosulphthalein by isolated rat hepatocytes.

D. Meijer, K. Keulemans, A. Blom, 1981, Biochemical pharmacology.

The cardiac glycoside sensitive step in the hepatic transport of the bisquaternary ammonium compound, hexafluorenium.

D. Meijer, J. Arends, J. G. Weitering, 1971, European journal of pharmacology.

Determination of dopaminergic prodrugs by high-performance liquid chromatography followed by post-column ion-pair extraction.

D. de Zeeuw, D. Meijer, D. Dijkstra, 1997, Journal of chromatography. B, Biomedical sciences and applications.

Modulators of the protein kinase C system influence biliary excretion of cationic drugs

D. Meijer, M. Merema, H. Steen, 1993, Hepatology.

Studies on the Mechanism of Binding and Uptake of Immune Complexes by Various Cell Types of Rat Liver in Vivo

D. Meijer, G. Harms, P. Hoedemaeker, 1986, Scandinavian journal of immunology.

Effect of nafenopin (SU-13,437) on liver function

D. Meijer, W. G. Levine, Ilana R. Braunstein, 2004, Naunyn-Schmiedeberg's Archives of Pharmacology.

Effect of nafenopin (SU-13, 437) on liver function

D. Meijer, W. G. Levine, J. Bognacki, 2004, Naunyn-Schmiedeberg's Archives of Pharmacology.

Novel therapeutic targets for the treatment of tubulointerstitial fibrosis

R. Kok, D. Meijer, H. Goor, 2008 .

Substantial excretion of digoxin via the intestinal mucosa and prevention of long‐term digoxin accumulation in the brain by the mdrla P‐glycoprotein

Piet Borst, J. Beijnen, P. Borst, 1996, British journal of pharmacology.

Effect of human liver source on the functionality of isolated hepatocytes and liver slices.

P. Olinga, G. Groothuis, D. Meijer, 1998, Drug metabolism and disposition: the biological fate of chemicals.

Comparison of human hepatocytes isolated from livers accepted or discarded for orthotopic transplantation.

G. Groothuis, J. Pruim, D. Meijer, 1995, Toxicology in vitro : an international journal published in association with BIBRA.

LPS-induced downregulation of MRP2 and BSEP in human liver is due to a posttranscriptional process.

K. Faber, P. Olinga, A. L. Draaisma, 2004, American journal of physiology. Gastrointestinal and liver physiology.

Development of vasculature targeting strategies for the treatment of cancer and chronic inflammatory diseases.

G. Molema, M. Everts, R. Kok, 2002, Biotechnology annual review.

Mechanistic aspects of uptake and sinusoidal efflux of dibromosulfophthalein in the isolated perfused rat liver.

G. Groothuis, D. Meijer, T. Pijning, 1991, Biochemical pharmacology.

CARRIER-MEDIATED TRANSPORT IN THE HANDLING OF DRUGS BY THE LIVER

G. Groothuis, D. Meijer, C. Neef, 1983 .

CD3 directed bispecific antibodies induce increased lymphocyte–endothelial cell interactions in vitro

B. Kroesen, G. Molema, D. Meijer, 2000, British Journal of Cancer.

Effects of a New Bioactive Lipid-Based Drug Carrier on Cultured Hepatic Stellate Cells and Liver Fibrosis in Bile Duct-Ligated Rats

J. Kamps, P. Zwiers, D. Meijer, 2007, Journal of Pharmacology and Experimental Therapeutics.

Effects of bioactive liposomes on cultured hepatic stellate cells and liver fibrosis in bile duct ligated rats chapter 4

J. Kamps, P. Zwiers, D. Meijer, 2006 .

Exacerbation of liver fibrosis after selective inhibition of cyclooxygenase-2 in Hepatic Stellate Cells

D. Meijer, A. Mallat, S. Lotersztajn, 2022 .

On the localisation of d-tubocurarine in rat liver lysosomes in vivo by electron microscopy and subcellular fractionation

G. Mulder, D. Meijer, M. Veenhuis, 2004, Naunyn-Schmiedeberg's Archives of Pharmacology.

Delivery of pharmacologically active dexamethasone into activated endothelial cells by dexamethasone-anti-E-selectin immunoconjugate.

Grietje Molema, G. Molema, M. Everts, 2003, Biochemical pharmacology.

Successful Targeting to Rat Hepatic Stellate Cells Using Albumin Modified with Cyclic Peptides That Recognize the Collagen Type VI Receptor*

D. Schuppan, P. de Bleser, G. Molema, 2000, The Journal of Biological Chemistry.

Investigations on the hepatic uptake systems for organic cations with a photoaffinity probe of procainamide ethobromide.

W. E. Mol, D. Meijer, M. Müller, 1992, Biochemical pharmacology.

CHOLESTASIS AND MUSCLE-RELAXANTS

D. Meijer, P. Westra, 1980 .

Comparison of "type I" and "type II" organic cation transport by organic cation transporters and organic anion-transporting polypeptides.

G. Groothuis, H. Koepsell, P. Meier, 2001, The Journal of pharmacology and experimental therapeutics.

Renal specific delivery of sulfamethoxazole in the rat by coupling to the low molecular weight protein lysozyme via an acid-sensitive linker

D. Meijer, D. Zeeuw, F. Moolenaar, 1992 .

Ukrain both as an anti cancer and immunoregulatory agent.

D. Meijer, V. Vatanasapt, W. Brzosko, 1992, Drugs under experimental and clinical research.

Targeting of RGD‐modified proteins to tumor vasculature: A pharmacokinetic and cellular distribution study

J. Proost, G. Molema, H. Moorlag, 2002, International journal of cancer.

A novel strategy to modify adenovirus tropism and enhance transgene delivery to activated vascular endothelial cells in vitro and in vivo.

M. Rots, G. Molema, H. Moorlag, 2004, Human gene therapy.

Choleresis and hepatic transport mechanisms

D. Meijer, R. Vonk, A. Scaf, 1977, Naunyn-Schmiedeberg's Archives of Pharmacology.

Precision-cut fibrotic rat liver slices as a new model to test the effects of anti-fibrotic drugs in vitro.

P. Olinga, G. Groothuis, D. Meijer, 2006, Journal of hepatology.

Vascular Endothelium in Inflamed Tissue as a Target for Site Selective Delivery of Drugs

G. Molema, M. Everts, D. Meijer, 2001 .

Charge modification of plasma and milk proteins results in antiviral active compounds

E. De Clercq, R. Pauwels, M. Harmsen, 1999, Journal of peptide science : an official publication of the European Peptide Society.

Abstracts of papers and posters Meeting on Pharmaceutical Sciences

S. W. F. Omta, Gert Luurtsema, John Urquhart, 1993, Pharmacy World and Science.

Specific delivery of captopril to the kidney with the prodrug captopril-lysozyme.

D. de Zeeuw, D. Meijer, F. Moolenaar, 1999, The Journal of pharmacology and experimental therapeutics.

Quantification of renal low-molecular-weight protein handling in the intact rat.

D. de Zeeuw, D. Meijer, A. V. van Zanten, 1993, Kidney international.

Analysis of in vitro lymphocyte adhesion and transendothelial migration by fluorescent-beads-based flow cytometric cell counting.

B. Kroesen, G. Molema, D. Meijer, 1998, Cytometry.

NEGATIVELY CHARGED ALBUMINS: A NOVEL CLASS OF POLYANIONIC PROTEINS WITH A POTENT ANTI-HIV-I ACTIVITY

D. Meijer, P. Swart, 1994 .

Anti-HIV-1 activity of combinations and covalent conjugates of negatively charged human serum albumins (NCAs) and AZT.

E. De Clercq, D. Meijer, M. Witvrouw, 1999, Journal of drug targeting.

A Phase I/IIa Study with Succinylated Human Serum Albumin (Suc-HSA), a candidate HIV-1 Fusion Inhibitor

J. Proost, F. Wit, D. Meijer, 2007, Antiviral Therapy.

The applicability of rat and human liver slices to the study of mechanisms of hepatic drug uptake.

P. Olinga, M. D. de Jager, G. Groothuis, 2001, Journal of pharmacological and toxicological methods.

Further studies into the mechanism of interaction of negatively charged human serum albumins with the V3 loop of the HIV-1 envelope protein Gp120

H. Schuitemaker, D. Meijer, M. Kuipers, 1995 .

Novel, negatively charged, human serum albumins display potent and selective in vitro anti-human immunodeficiency virus type 1 activity.

E. De Clercq, R. Pauwels, D. Meijer, 1993, Molecular pharmacology.

Human liver slices as an in vitro model to study toxicity-induced hepatic stellate cell activation in a multicellular milieu.

P. Olinga, G. Groothuis, D. Meijer, 2006, Chemico-biological interactions.

Precision-cut liver slices as a new model to study toxicity-induced hepatic stellate cell activation in a physiologic milieu.

P. Olinga, S. Friedman, A. L. Draaisma, 2005, Toxicological sciences : an official journal of the Society of Toxicology.

Effect of pentoxifylline on stellate cell activation in human liver slices

P. Olinga, G. Groothuis, D. Meijer, 2018 .

University of Groningen Liver fibrosis in vitro

P. Olinga, G. Groothuis, D. Meijer, 2017 .

Liver slices as a model to study fibrogenesis and test the effects of anti-fibrotic drugs on fibrogenic cells in human liver.

P. Olinga, G. Groothuis, D. Meijer, 2008, Toxicology in Vitro.

Cellular distribution and handling of liver-targeting preparations in human livers studied by a liver lobe perfusion.

P. Olinga, G. Groothuis, D. Meijer, 2001, Drug metabolism and disposition: the biological fate of chemicals.

Cellular distribution and handling of liver-targeting preparations in human livers studied by a liver lobe perfusion.

P. Olinga, G. Groothuis, D. Meijer, 2001, Drug metabolism and disposition: the biological fate of chemicals.

The influence of binding to albumin and α1-acid glycoprotein on the clearance of drugs by the liver

P. Sluijs, D. Meijer, Dirk K. F. Meijer, 1987, Pharmaceutisch Weekblad.

A novel lipid-based drug carrier targeted to the non-parenchymal cells, including hepatic stellate cells, in the fibrotic livers of bile duct ligated rats.

P. Terpstra, J. Kamps, D. Meijer, 2007, Biochimica et biophysica acta.

Absorption kinetics of oral and rectal flecainide in healthy subjects

J. Proost, D. Meijer, J. Kingma, 2004, European Journal of Clinical Pharmacology.

Tumor Vascular Endothelium: Barrier or Target in Tumor Directed Drug Delivery and Immunotherapy

Grietje Molema, G. Molema, D. Meijer, 2004, Pharmaceutical Research.

Stereoselective inhibition by the diastereomers quinidine and quinine of uptake of cardiac glycosides into isolated rat hepatocytes.

D. Meijer, A. Hedman, 1998, Journal of pharmaceutical sciences.

Hepatic uptake and biliary excretion of dibromosulphthalein. Albumin dependence, influence of phenobarbital and nafenopin pretreatment and the role of y and z protein.

D. Meijer, R. Vonk, J. G. Weitering, 1977, The Journal of pharmacology and experimental therapeutics.

Uptake of taurocholic acid in human hepatocytes isolated from livers of donors of different age.

P. Olinga, G. Groothuis, D. Meijer, 1998, Journal of pediatric gastroenterology and nutrition.

Human Liver Slices Express the Same Lidocaine Biotransformation Rate as Isolated Human Hepatocytes

P. Olinga, G. Groothuis, D. Meijer, 1993 .

A new technique for preparing precision-cut slices from small intestine and colon for drug biotransformation studies.

R. de Kanter, A. L. Draaisma, M. D. de Jager, 2005, Journal of pharmacological and toxicological methods.

Effect of ethanol on hepatobiliary transport of cationic drugs. A study in the isolated perfused rat liver, rat hepatocytes and rat mitochondria.

D. Meijer, M. Merema, H. Steen, 1994, Journal of hepatology.

Synthesis of 4‐Azido‐N‐[2‐(diethylmethylammonium)ethyl]benzamide Iodide: A Photolabile Derivative of Procainamidethobromide

D. Meijer, Michael Müller, G. Kurz, 1989 .

The Antiproliferative Drug Doxorubicin Inhibits Liver Fibrosis in Bile Duct-Ligated Rats and Can Be Selectively Delivered to Hepatic Stellate Cells in Vivo

D. Meijer, H. Bakker, R. Greupink, 2006, Journal of Pharmacology and Experimental Therapeutics.

Disposition kinetics and bioavailability of the glucosidase inhibitor N-benzyl-1-deoxynojirimycin after various routes of administration in mice

D. Meijer, L. Delbressine, L. V. D. Broek, 1997 .

Oxford Textbook of Clinical Hepatology

G. Groothuis, D. Meijer, 1999 .

Measurement of the association of cholephylic organic anions with different binding proteins.

D. Meijer, C. Tiribelli, G. Sottocasa, 1985, Biochemical pharmacology.

Rectal absorption of metronidazol from polyethylene glycol suppositories

D. Meijer, H. Vromans, F. Moolenaar, 1984, Pharmaceutisch Weekblad.

RECTAL ABSORPTION OF METHADONE FROM DISSOLUTION-PROMOTING VEHICLES

D. Meijer, F. Moolenaar, J. Visser, 1986 .

Rectal versus oral absorption of diflunisal in man

D. Meijer, F. Moolenaar, J. Visser, 1984 .

Rectal versus oral absorption of codeine phosphate in man.

D. Meijer, F. Moolenaar, J. Visser, 1983, Biopharmaceutics & drug disposition.

Pharmacokinetics of the hepatic transport of organic anions: Influence of extra- and intracelluar binding on hepatic storage of dibromosulfophthalein and interactions with indocyanine green

D. Meijer, J. G. Weitering, A. Blom, 1984, Journal of Pharmacokinetics and Biopharmaceutics.

Pharmacokinetic modeling of the sinusoidal efflux of anionic ligands from the isolated perfused rat liver: The influence of albumin

J. Proost, G. Groothuis, D. Meijer, 1993, Journal of Pharmacokinetics and Biopharmaceutics.

Pharmacokinetics of biliary excretion in man. VI. Indocyanine green

D. Meijer, D. K. F. Meijer, G. A. Vermeer, 2004, European Journal of Clinical Pharmacology.

The influence of phenobarbital pretreatment on the subcellular distribution in liver and transport rate in isolated hepatocytes of dibromosulfophthalein.

D. Meijer, J. G. Weitering, A. Blom, 1982, Biochemical pharmacology.

The influence of dehydrocholate on hepatic uptake and biliary excretion of 3H-taurocholate and 3H-ouabain.

D. Meijer, R. Vonk, W. G. Levine, 1976, Drug metabolism and disposition: the biological fate of chemicals.

The stereoisomers quinine and quinidine exhibit a marked stereoselectivity in the inhibition of hepatobiliary transport of cardiac glycosides.

D. Meijer, A. Hedman, 1998, Journal of hepatology.

Drug-targeting to the kidney: renal delivery and degradation of a naproxen-lysozyme conjugate in vivo.

D. de Zeeuw, D. Meijer, P. D. de Jong, 1997, Kidney international.

Local Inhibition of Liver Fibrosis by Specific Delivery of a Platelet-Derived Growth Factor Kinase Inhibitor to Hepatic Stellate Cells

G. Kéri, R. Kok, D. Meijer, 2007, Journal of Pharmacology and Experimental Therapeutics.

Manipulation of rectal absorption rate of phenytoin in man

D. Meijer, F. Moolenaar, J. Visser, 1981, Pharmaceutisch weekblad.

Transport of organic ions through lipid bilayers

D. Meijer, P. G. Ruifrok, 1981, Naunyn-Schmiedeberg's Archives of Pharmacology.

CHARACTERIZATION OF RAT SMALL INTESTINAL AND COLON PRECISION-CUT SLICES AS AN IN VITRO SYSTEM FOR DRUG METABOLISM AND INDUCTION STUDIES

M. D. de Jager, I. A. D. de Graaf, G. Groothuis, 2005, Drug Metabolism and Disposition.

Mechanisms for the hepatic uptake and biliary excretion of tributylmethylammonium: studies with rat liver plasma membrane vesicles.

D. Meijer, H. Smit, W. Wang, 1996, The Journal of pharmacology and experimental therapeutics.

Hepatocyte heterogeneity in bile formation and hepatobiliary transport of drugs.

D. Meijer, G. Groothuis, G. Groothuis, 1992, Enzyme.

Differential effects of metabolic inhibitors on cellular and mitochondrial uptake of organic cations in rat liver.

J. Maring, D. Meijer, H. Steen, 1993, Biochemical pharmacology.

Pharmacokinetics of the oral narcotic analgesic bezitramide and preliminary observations on its effect on experimentally induced pain

D. Meijer, F. Moolenaar, H. Wesseling, 2004, European Journal of Clinical Pharmacology.

Rat liver slices as a tool to study LPS-induced inflammatory response in the liver.

P. Olinga, M. D. de Jager, G. Groothuis, 2001, Journal of hepatology.

Selective activity of several cholic acid derivatives against human immunodeficiency virus replication in vitro.

E. De Clercq, R. Pauwels, D. Meijer, 1989, Journal of Acquired Immune Deficiency Syndromes.

Renal targeting of a non-steroidal anti-inflammatory drug: effects on renal prostaglandin synthesis in the rat.

D. de Zeeuw, D. Meijer, P. D. de Jong, 1998, Clinical science.

The pharmacokinetics of beta-cyclodextrin and hydroxypropyl-beta-cyclodextrin in the rat.

C. Lerk, H. Frijlink, D. Meijer, 1990, Pharmaceutical research.

RGD-modified anti-CD3 antibodies redirect cytolytic capacity of cytotoxic T lymphocytes toward alphavbeta3-expressing endothelial cells.

S. Withoff, G. Molema, R. Kok, 2004, International journal of cancer.

The capability of isolated hepatocytes and liver slices of donor livers to predict graft function after liver transplantation.

P. Olinga, G. Groothuis, D. Meijer, 2000, Liver.

A rapid and simple method for cryopreservation of human liver slices.

P. Olinga, R. de Kanter, M. D. de Jager, 1998, Xenobiotica; the fate of foreign compounds in biological systems.

Effect of cold and warm ischaemia on drug metabolism in isolated hepatocytes and slices from human and monkey liver.

P. Olinga, M. D. de Jager, D. Meijer, 1998, Xenobiotica; the fate of foreign compounds in biological systems.

Anti-human cytomegalovirus effects of breast milk - Reply

D. Meijer, M. Harmsen, J. Nuijens, 1996 .

High‐Performance Liquid Chromatographic Assay of Flecainide and Its Enantiomers in Serum

D. Meijer, J. Kingma, R. M. Stuurman, 1989, Therapeutic drug monitoring.

The action of flecainide acetate and its enantiomers on mammalian non-myelinated nerve fibres

A. Hertog, D. Meijer, J. Akker, 1989, Pharmaceutisch Weekblad.

Transport mechanisms for cationic drugs and proteins in kidney, liver and intestine: implication for drug interactions and cell-specific drug delivery.

D. de Zeeuw, P. Meier, D. Meijer, 1999, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Disease-induced drug targeting using novel peptide-ligand albumins.

G. Molema, D. Meijer, L. Beljaars, 2001, Journal of controlled release : official journal of the Controlled Release Society.

PRESERVATION OF RAT LIVERS AND ISOLATED RAT AND HUMAN HEPATOCYTES IN UW SOLUTION

G. Groothuis, D. Meijer, M. Slooff, 1989 .

Hepatobiliary secretion of organic compounds; molecular mechanisms of membrane transport.

D. Meijer, G. Groothuis, D. Meijer, 1995, Biochimica et biophysica acta.

Zonal distribution of the cation lucigenin in rat liver: influence of taurocholate.

G. Groothuis, D. Meijer, T. Pijning, 1989, Molecular pharmacology.

Vesicular uptake system for the cation lucigenin in the rat hepatocyte.

G. Groothuis, D. Meijer, T. Pijning, 1989, Molecular Pharmacology.

Influence of taurocholate on hepatic clearance and biliary excretion of asialo intestinal alkaline phosphatase in the rat in vivo and in isolated perfused rat liver.

G. Groothuis, D. Meijer, J. G. Weitering, 1983, Gastroenterology.

Hepatic uptake and biliary excretion of organic cations--II. The influence of ion pair formation.

D. Meijer, C. Neef, K. Keulemans, 1984, Biochemical pharmacology.

Urine collection in the freely moving rat: reliability for measurement of short-term renal effects.

D. de Zeeuw, D. Meijer, P. D. de Jong, 1997, Journal of pharmacological and toxicological methods.

Delivery of Drugs and Antisense Oligonucleotides to the Proximal Tubular Cell of the Kidney Using Macromolecular and Pro‐drug Approaches

Y. Sugiyama, D. Meijer, Y. Kato, 2001 .

Optimization of the reaction conditions for the synthesis of neoglycoprotein-AZT-monophosphate conjugates.

D. Meijer, M. Hendriks, M. Kuipers, 1995, Journal of Medicinal Chemistry.

Mechanisms for the uptake of cationic drugs by the liver: a study with tributylmethylammonium (TBuMA).

D. Meijer, R. Oosting, H. Steen, 1991, The Journal of pharmacology and experimental therapeutics.

Drug-metabolizing activity of human and rat liver, lung, kidney and intestine slices

P. Olinga, R. de Kanter, A. L. Draaisma, 2002, Xenobiotica; the fate of foreign compounds in biological systems.

Prediction of whole-body metabolic clearance of drugs through the combined use of slices from rat liver, lung, kidney, small intestine and colon

R. de Kanter, M. Monshouwer, A. L. Draaisma, 2004, Xenobiotica; the fate of foreign compounds in biological systems.

Drug uptake systems in liver and kidney.

D. Meijer, G. Groothuis, H. Koepsell, 2003, Current drug metabolism.

Gliotoxin non‐selectively induces apoptosis in fibrotic and normal livers

P. Olinga, G. Groothuis, D. Meijer, 2006, Liver international : official journal of the International Association for the Study of the Liver.

CHARACTERIZATION OF RAT SMALL INTESTINAL AND COLON PRECISION-CUT SLICES AS AN IN VITRO SYSTEM FOR DRUG METABOLISM AND INDUCTION STUDIES

M. D. de Jager, I. A. D. de Graaf, G. Groothuis, 2005, Drug Metabolism and Disposition.

Inhibition of renal rho kinase attenuates ischemia/reperfusion-induced injury.

R. Kok, D. Meijer, H. van Goor, 2008, Journal of the American Society of Nephrology : JASN.

The Antiviral Protein Human Lactoferrin Is Distributed in the Body to Cytomegalovirus (CMV) Infection-Prone Cells and Tissues

G. Molema, D. Meijer, H. Bakker, 2004, Pharmaceutical Research.

PHARMACOKINETICS OF BILIARY-EXCRETION IN MAN - PLASMA DISAPPEARANCE OF INDOCYANINE GREEN IN RELATION TO ITS EXCRETION RATE

D. Meijer, B. Weert, G. Vermeer, 1984 .

Novel therapeutic targets for the treatment of tubulointerstitial fibrosis

R. Kok, D. Meijer, H. Goor, 2008 .

HEPATIC-UPTAKE AND BILIARY-EXCRETION OF DIBROMOSULFTHALEIN (DBSP) IN RAT AND IN MAN

D. Meijer, J. G. Weitering, K. Keulemans, 1980 .

Hepatobiliary excretion of organic anions in double-mutant rats with a combination of defective canalicular transport and uridine 5'-diphosphate-glucuronyltransferase deficiency.

D. Meijer, D. Meijer, P. Jansen, 1987, Gastroenterology.