J. Schwaller

发表

A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases

S. Knapp, O. Fedorov, S. Müller, 2007, Proceedings of the National Academy of Sciences.

PFI-1, a highly selective protein interaction inhibitor, targeting BET Bromodomains.

S. Knapp, J. Bradner, O. Fedorov, 2013, Cancer research.

Molecular mechanisms of myeloid malignancies: on the hunt for new therapeutic targets

J. Schwaller, J. Cools, 2004 .

Targeting PIM kinases impairs survival of hematopoietic cells transformed by kinase inhibitor-sensitive and kinase inhibitor-resistant forms of Fms-like tyrosine kinase 3 and BCR/ABL.

M. Nawijn, C. Thompson, V. Pogačić, 2006, Cancer research.

CXCR4-SERINE339 regulates cellular adhesion, retention and mobilization, and is a marker for poor prognosis in acute myeloid leukemia

J. Schwaller, A. Tzankov, C. Dierks, 2014, Leukemia.

Cancer Biology and Signal Transduction Pim Kinases Are Essential for Chronic Lymphocytic Leukemia Cell Survival (pim2/3) and Cxcr4-mediated Microenvironmental Interactions (pim1)

N. Gray, H. Eibel, J. Schwaller, 2022 .

PIM kinases are progression markers and emerging therapeutic targets in diffuse large B-cell lymphoma

S. Knapp, J. Schwaller, E. Obermann, 2012, British Journal of Cancer.

Downregulation of 14-3-3σ in ovary, prostate and endometrial carcinomas is associated with CpG island methylation

H. Hermeking, F. Herrmann, H. Koeffler, 2005, Modern Pathology.

High-throughput kinase profiling: a more efficient approach toward the discovery of new kinase inhibitors.

Randall W King, Xianming Deng, Stefan Knapp, 2011, Chemistry & biology.

Socs-1 Inhibits TEL-JAK2-Mediated Transformation of Hematopoietic Cells through Inhibition of JAK2 Kinase Activity and Induction of Proteasome-Mediated Degradation

J. Kutok, D. Gilliland, J. Schwaller, 2001, Molecular and Cellular Biology.

Structural analysis identifies imidazo[1,2-b]pyridazines as PIM kinase inhibitors with in vitro antileukemic activity.

S. Knapp, O. Fedorov, A. Bullock, 2007, Cancer research.

Validation and structural characterization of the LEDGF/p75-MLL interface as a new target for the treatment of MLL-dependent leukemia.

J. Schwaller, V. Veverka, K. Cermakova, 2014, Cancer research.

THE EF-HAND CA-BINDING PROTEIN SUPER-FAMILY: A GENOME-WIDE ANALYSIS OF GENE EXPRESSION PATTERNS IN THE ADULT MOUSE BRAIN

J. Schwaller, F. Girard, 2015 .

Dissection of PIM serine/threonine kinases in FLT3-ITD–induced leukemogenesis reveals PIM1 as regulator of CXCL12–CXCR4-mediated homing and migration

Stefan Knapp, Andrea Biondi, Antonello Villa, 2009, The Journal of experimental medicine.

Cancer Biology and Signal Transduction PIM Kinases Are Essential for Chronic Lymphocytic Leukemia Cell Survival ( PIM 2 / 3 ) and CXCR 4-Mediated Microenvironmental Interactions ( PIM 1 )

N. Gray, H. Eibel, J. Schwaller, 2014 .

Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia

A. Gingras, S. Knapp, O. Dovey, 2016, Science Advances.