A. Verhee

发表

Molecular basis of the membrane-anchored and two soluble isoforms of the human interleukin 5 receptor alpha subunit.

J. Tavernier, R. Devos, T. Tuypens, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Interleukin 5 regulates the isoform expression of its own receptor alpha-subunit.

J. Vandekerckhove, J. Tavernier, J. van der Heyden, 2000, Blood.

Design and application of a cytokine-receptor-based interaction trap

Jan Tavernier, Joël Vandekerckhove, Irma Lemmens, 2001, Nature Cell Biology.

Selection of non-competitive leptin antagonists using a random nanobody-based approach.

J. Tavernier, L. Zabeau, D. Catteeuw, 2012, The Biochemical journal.

Analyzing trapped protein complexes by Virotrap and SFINX

Jan Tavernier, Kris Gevaert, Sven Eyckerman, 2017, Nature Protocols.

MAPPIT (MAmmalian Protein-Protein Interaction Trap) as a tool to study HIV reverse transcriptase dimerization in intact human cells.

I. Lemmens, J. Tavernier, S. Lievens, 2008, Journal of virological methods.

Identification of receptor-binding domains on human interleukin 5 and design of an interleukin 5-derived receptor antagonist.

J. Tavernier, C. Oefner, R. Devos, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Rapid and Effective Generation of Nanobody Based CARs using PCR and Gibson Assembly

J. Tavernier, J. van der Heyden, A. Verhee, 2020, International journal of molecular sciences.

Delivering Type I Interferon to Dendritic Cells Empowers Tumor Eradication and Immune Combination Treatments.

J. Tavernier, N. Kley, D. Catteeuw, 2018, Cancer research.

Safe eradication of large established tumors using neovasculature‐targeted tumor necrosis factor‐based therapies

J. Tavernier, J. Bultinck, N. Kley, 2020, EMBO molecular medicine.

interactions on receptor basic operating procedures for screening protein

Jan Tavernier, Sven Eyckerman, Xaveer Van Ostade, 2001 .

A Hydrophobic Cluster at the Surface of the Human Plasma Phospholipid Transfer Protein Is Critical for Activity on High Density Lipoproteins*

J. Tavernier, J. Vandekerckhove, A. Verhee, 2001, The Journal of Biological Chemistry.

Recombinant soluble human interleukin-5 (hIL-5) receptor molecules. Cross-linking and stoichiometry of binding to IL-5.

J. Tavernier, R. Devos, S. Cornelis, 1993, The Journal of biological chemistry.

Molecular basis of the membrane-anchored and two soluble isoforms of the human interleukin 5 receptor alpha subunit.

J. Tavernier, R. Devos, T. Tuypens, 1992, Proceedings of the National Academy of Sciences of the United States of America.

The cell surface expression level of the human interleukin-5 receptor alpha subunit determines the agonistic/antagonistic balance of the human interleukin-5 E13Q mutein.

J. Vandekerckhove, J. Tavernier, A. Verhee, 2001, European journal of biochemistry.

Neutralizing monoclonal antibodies can potentiate IL‐5 signaling

J. Tavernier, J. Vandekerckhove, P. Heinrich, 2001, European journal of immunology.

Targeting IFN activity to both B cells and plasmacytoid dendritic cells induces a robust tolerogenic response and protection against EAE

J. Tavernier, N. Kley, M. Prinz, 2021, Scientific Reports.

Headgroup specificity of lecithin cholesterol acyltransferase for monomeric and vesicular phospholipids.

J. Tavernier, J. Vandekerckhove, A. Verhee, 2000, Biochimica et biophysica acta.

Relationship between structure and biochemical phenotype of lecithin:cholesterol acyltransferase (LCAT) mutants causing fish-eye disease.

J. Tavernier, J. Vandekerckhove, A. Verhee, 2000, Journal of lipid research.

Targeting interferon activity to dendritic cells enables in vivo tolerization and protection against EAE in mice.

J. Tavernier, N. Kley, M. Prinz, 2019, Journal of autoimmunity.

A sensitive and versatile bioassay for ligands that signal through receptor clustering.

J. Vandekerckhove, J. Tavernier, A. Verhee, 2000, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

Dimerization of the Interferon Type I Receptor IFNaR2–2 Is Sufficient for Induction of Interferon Effector Genes but Not for Full Antiviral Activity*

J. Tavernier, J. Vandekerckhove, A. Verhee, 1999, The Journal of Biological Chemistry.

Definition of the interacting interfaces of Apobec3G and HIV-1 Vif using MAPPIT mutagenesis analysis

J. Tavernier, R. Clayton, D. Catteeuw, 2009, Nucleic acids research.

HyperISGylation of Old World Monkey ISG15 in Human Cells

J. Tavernier, J. Vandekerckhove, K. Gevaert, 2008, PloS one.

A safe and highly efficient tumor-targeted type I interferon immunotherapy depends on the tumor microenvironment

Jan Tavernier, Annick Verhee, Elke Rogge, 2018, Oncoimmunology.

Trapping mammalian protein complexes in viral particles

Jan Tavernier, Kris Gevaert, Sven Eyckerman, 2016, Nature Communications.

Identification and expression analysis of leptin-regulated immediate early response and late target genes.

J. Tavernier, J. Vandekerckhove, S. Eyckerman, 2000, The Biochemical journal.

A proposed architecture for lecithin cholesterol acyl transferase (LCAT): Identification of the catalytic triad and molecular modeling

J. Tavernier, A. Verhee, M. Rosseneu, 1998, Protein science : a publication of the Protein Society.

Identification of the Y985 and Y1077 motifs as SOCS3 recruitment sites in the murine leptin receptor

J. Tavernier, J. Vandekerckhove, S. Eyckerman, 2000, FEBS letters.

Mammalian protein-protein interaction trap (MAPPIT) analysis of STAT5, CIS, and SOCS2 interactions with the growth hormone receptor.

I. Lemmens, Anne-Sophie de Smet, J. Tavernier, 2007, Molecular Endocrinology.

Mapping of the Leptin Binding Sites and Design of a Leptin Antagonist*

J. Tavernier, L. Zabeau, D. Catteeuw, 2004, Journal of Biological Chemistry.

Design and Use of a Mammalian Protein-Protein Interaction Trap (MAPPIT)

I. Lemmens, J. Tavernier, S. Lievens, 2002, Science's STKE.

Characterization of functional residues in the interfacial recognition domain of lecithin cholesterol acyltransferase (LCAT).

R. Brasseur, J. Tavernier, J. Vandekerckhove, 1999, Protein Engineering.

Phosphorylation by Protein Kinase CK2 Modulates the Activity of the ATP Binding Cassette A1 Transporter*

J. Tavernier, J. Vandekerckhove, M. Lensink, 2004, Journal of Biological Chemistry.

Effect of mutations of N- and C-terminal charged residues on the activity of LCAT.

J. Tavernier, J. Vandekerckhove, A. Verhee, 2001, Journal of lipid research.

Leptin’s metabolic and immune functions can be uncoupled at the ligand/receptor interaction level

J. Tavernier, K. Venken, H. Chen, 2014, Cellular and Molecular Life Sciences.

Analysis of Tyr to Phe and fa/fa leptin receptor mutations in the PC12 cell line.

J. Tavernier, J. Vandekerckhove, S. Eyckerman, 1999, European cytokine network.

Antagonism and selective modulation of the human glucocorticoid receptor both reduce recruitment of p300/CBP and the Mediator complex

R. Houtman, K. Gevaert, S. Eyckerman, 2023, bioRxiv.

Comparison of leptin- and interleukin-6-regulated expression of the rPAP gene family: evidence for differential co-regulatory signals.

J. Tavernier, J. Vandekerckhove, S. Eyckerman, 2002, European cytokine network.

Leptin’s metabolic and immune functions can be uncoupled at the ligand/receptor interaction level

J. Tavernier, K. Venken, J. Rubio, 2014, Cellular and Molecular Life Sciences.

Reverse MAPPIT: screening for protein-protein interaction modifiers in mammalian cells

I. Lemmens, J. Tavernier, S. Lievens, 2005, Nature Methods.

Delivering Type I Interferon to Dendritic Cells Empowers Tumor Eradication and Immune Combination Treatments.

J. Tavernier, N. Kley, A. Verhee, 2018, Cancer research.

A bispecific Clec9A-PD-L1 targeted type I interferon profoundly reshapes the tumor microenvironment towards an antitumor state

A. Verhee, Nele Vanderroost, A. Cauwels, 2023, Molecular Cancer.