J. Gern

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Decreased expression of membrane IL-5 receptor alpha on human eosinophils: I. Loss of membrane IL-5 receptor alpha on airway eosinophils and increased soluble IL-5 receptor alpha in the airway after allergen challenge.

Lin Ying Liu, W. Busse, M. Bates, 2002, Journal of immunology.

Decreased Expression of Membrane IL-5 Receptor α on Human Eosinophils: I. Loss of Membrane IL-5 Receptor α on Airway Eosinophils and Increased Soluble IL-5 Receptor α in the Airway After Allergen Challenge1

Lin Ying Liu, W. Busse, M. Bates, 2002, The Journal of Immunology.

Comparison of Temporal Transcriptomic Profiles from Immature Lungs of Two Rat Strains Reveals a Viral Response Signature Associated with Chronic Lung Dysfunction

Jamie M. Verheyden, Ning Leng, C. Kendziorski, 2014, PloS one.

Classification and evolution of human rhinoviruses.

J. Gern, A. Palmenberg, 2015, Methods in molecular biology.

The Infant Nasopharyngeal Microbiome Impacts Severity of Lower Respiratory Infection and Risk of Asthma Development

M. Inouye, S. Johnston, K. Holt, 2015, Cell Host & Microbe.

The Sequence of the Human Genome

J. Gern, 2001, Science.

Evaluation of the modified asthma predictive index in high-risk preschool children.

M. Coen, R. Gangnon, J. Gern, 2013, The journal of allergy and clinical immunology. In practice.

Section on Allergy and Immunology

Paul D. Williams, W. Dolen, J. Church, 2011, Pediatrics.

Antiviral IFN-γ responses of monocytes at birth predict respiratory tract illness in the first year of life

J. Gern, M. Holtzman, G. Bloomberg, 2012, Journal of Allergy and Clinical Immunology.

Actionable diagnosis of neuroleptospirosis by next-generation sequencing.

Joseph L DeRisi, Steve Miller, Charles Y Chiu, 2014, The New England journal of medicine.

Effects of viral respiratory infections on lung development and childhood asthma.

Ronald L Sorkness, R. Sorkness, J. Gern, 2005, The Journal of allergy and clinical immunology.

Molecular identification and quantification of human rhinoviruses in respiratory samples.

Wai-ming Lee, R. Vrtis, J. Gern, 2015, Methods in molecular biology.

Human rhinovirus species and season of infection determine illness severity.

Wai-ming Lee, R. Gangnon, J. Gern, 2012, American journal of respiratory and critical care medicine.

Rhinovirus-induced Interferon-γ and Airway Responsiveness in Asthma

W. Busse, J. Gern, C. Swenson, 2003 .

Rhinovirus-induced PBMC responses and outcome of experimental infection in allergic subjects.

W. Busse, J. Gern, C. Swenson, 2000, The Journal of allergy and clinical immunology.

Rhinovirus-specific T cells recognize both shared and serotype-restricted viral epitopes.

R. Vrtis, J. Gern, E. A. Kelly, 1997, The Journal of infectious diseases.

Safe administration of influenza vaccine to patients with egg allergy.

H. Sampson, J. Gern, R. Zeiger, 1998, The Journal of pediatrics.

Prenatal maternal stress and cord blood innate and adaptive cytokine responses in an inner-city cohort.

Diane R Gold, Rosalind J Wright, Yoel Sadovsky, 2010, American journal of respiratory and critical care medicine.

International consensus on (ICON) pediatric asthma

H. Zar, G. Wennergren, T. Casale, 2012, Allergy.

The role of viral infections in the natural history of asthma.

W. Busse, J. Gern, 2000, The Journal of allergy and clinical immunology.

The association of allergic sensitization patterns in early childhood with disease manifestations and immunological reactivity at 10 years of age

G. O'Connor, A. Togias, A. Sette, 2019, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Allele-specific targeting of microRNAs to HLA-G and risk of asthma.

Carole Ober, Blanca Camoretti-Mercado, Jihua Fan, 2007, American journal of human genetics.

Real-world comparison of two molecular methods for detection of respiratory viruses

Wai-ming Lee, K. Edwards, John V. Williams, 2011, Virology Journal.

Rhinoviruses and Their Receptors

J. Gern, A. Palmenberg, Sarmila Basnet, 2019, Chest.

Rhinoviruses and Their Receptors: Implications for Allergic Disease

J. Gern, Y. Bochkov, 2016, Current Allergy and Asthma Reports.

The Urban Environment and Childhood Asthma study.

J. Gern, 2010, The Journal of allergy and clinical immunology.

New visions in respiratory allergy (asthma and allergic rhinitis): An iPAC summary and future trends

N. Papadopoulos, J. Gern, M. Borres, 2008, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

Rhinovirus 3C protease precursors 3CD and 3CD' localize to the nuclei of infected cells.

J. Gern, A. Palmenberg, S. Amineva, 2004, The Journal of general virology.

Effects of Vitamin D on Airway Epithelial Cell Morphology and Rhinovirus Replication

J. Gern, R. Pickles, R. Brockman-Schneider, 2014, PloS one.

LPS modulates rhinovirus-induced chemokine secretion in monocytes and macrophages.

M. Gavala, P. Keely, J. Gern, 2014, American journal of respiratory cell and molecular biology.

Circulating TSLP associates with decreased wheezing in non‐atopic preschool children: data from the URECA birth cohort

P. Gergen, G. O'Connor, Raphael Kopan, 2014, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Longitudinal relationship of early life immunomodulatory T cell phenotype and function to development of allergic sensitization in an urban cohort

P. Wallace, J. Gern, D. Gold, 2012, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Role of viral respiratory infections in asthma and asthma exacerbations

William W Busse, W. Busse, J. Gern, 2010, The Lancet.

Distinct Nasal Airway Bacterial Microbiota Differentially Relate to Exacerbation in Pediatric Asthma.

H. Boushey, A. Togias, J. Gern, 2019, The Journal of allergy and clinical immunology.

The influence of atopy and asthma on immune responses in inner‐city adults

G. O'Connor, L. Bacharier, F. Witter, 2016, Immunity, inflammation and disease.

31 Infections and Asthma Impact on the Natural History of Asthma

J. Gern, R. Lemanske, D. Jackson, 2016, Pediatric Allergy: Principles and Practice.

Interferon gene expression in sputum cells correlates with the Asthma Index Score during virus‐induced exacerbations

N. Jarjour, J. Gern, L. Denlinger, 2014, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Comparison of viral load in individuals with and without asthma during infections with rhinovirus.

Wai-ming Lee, J. Patrie, W. Woods, 2014, American journal of respiratory and critical care medicine.

Viral bronchiolitis in young rats causes small airway lesions that correlate with reduced lung function.

R. Sorkness, J. Gern, R. Lemanske, 2013, American journal of respiratory cell and molecular biology.

Lower Respiratory Tract Infection Induced by a Genetically Modified Picornavirus in Its Natural Murine Host

R. Sorkness, J. Gern, R. Szakaly, 2012, PloS one.

Asthma and pregnancy: do they give clues to abnormal antiviral activity?

W. Busse, J. Gern, 2011, Thorax.

Relationship of upper and lower airway cytokines to outcome of experimental rhinovirus infection.

W. Busse, R. Vrtis, J. Gern, 2000, American journal of respiratory and critical care medicine.

Rhinovirus-induced interferon-gamma and airway responsiveness in asthma.

W. Busse, J. Gern, C. Swenson, 2003, American journal of respiratory and critical care medicine.

Quantitative and qualitative analysis of rhinovirus infection in bronchial tissues.

W. Busse, Wai-ming Lee, N. Jarjour, 2005, American journal of respiratory and critical care medicine.

Rhinovirus illnesses during infancy predict subsequent childhood wheezing.

R. Gangnon, J. Gern, R. Lemanske, 2005, The Journal of allergy and clinical immunology.

Wheezing rhinovirus illnesses in early life predict asthma development in high-risk children.

Wai-ming Lee, R. Gangnon, J. Gern, 2008, American journal of respiratory and critical care medicine.

Basal cells of differentiated bronchial epithelium are more susceptible to rhinovirus infection.

Wai-ming Lee, J. Gern, B. Jakiela, 2008, American journal of respiratory cell and molecular biology.

W. Busse, R. Sorkness, R. Vrtis, 2009, The Journal of allergy and clinical immunology.

Research Priorities in Pediatric Asthma: Results of a Global Survey of Multiple Stakeholder Groups by the Pediatric Asthma in Real Life (PeARL) Think Tank.

D. Price, A. Sheikh, H. Zar, 2020, The journal of allergy and clinical immunology. In practice.

Distribution and seasonality of rhinovirus and other respiratory viruses in a cross-section of asthmatic children in Trinidad, West Indies

Wai-ming Lee, J. Gern, R. Lemanske, 2009, Italian journal of pediatrics.

W. Busse, J. Sedgwick, J. Gern, 2002, The Journal of infectious diseases.

Asthma in Non–Inner City Head Start Children

W. Busse, C. Sorkness, J. Gern, 1998, Pediatrics.

Rhinovirus inhibits antigen-specific T cell proliferation through an intercellular adhesion molecule-1-dependent mechanism.

J. Gern, E. Dick, W. Borcherding, 1996, The Journal of infectious diseases.

Respiratory health, allergies, and the farm environment: design, methods and enrollment in the observational Wisconsin Infant Study Cohort (WISC): a research proposal

Brent F. Olson, Kathrine L. Barnes, Casper G Bendixsen, 2019, BMC Research Notes.

Efficacy and safety of treatment with biologicals (benralizumab, dupilumab and omalizumab) for severe allergic asthma: A systematic review for the EAACI Guidelines ‐ recommendations on the use of biologicals in severe asthma

T. Casale, N. Papadopoulos, I. Agache, 2020, Allergy.

Emerging concepts and challenges in implementing the exposome paradigm in allergic diseases and asthma: a Practall document

I. Agache, A. Muraro, P. Hellings, 2018, Allergy.

THE ROLE OF RESPIRATORY VIRUSES IN ACUTE AND CHRONIC ASTHMA

J. Gern, R. Lemanske, A. Tuffaha, 2000, Clinics in Chest Medicine.

Allergic reactions to milk-contaminated "nondairy" products.

H. Sampson, J. Gern, E. Yang, 1991, The New England journal of medicine.

NIAID, NIEHS, NHLBI, and MCAN Workshop Report: The indoor environment and childhood asthma—implications for home environmental intervention in asthma prevention and management

G. O'Connor, A. Custovic, J. Celedón, 2017, The Journal of allergy and clinical immunology.

Allergen‐induced activation of natural killer cells represents an early‐life immune response in the development of allergic asthma

Scott R. Presnell, Matthew C. Altman, W. Busse, 2018, The Journal of allergy and clinical immunology.

Viral respiratory infection and the link to asthma

J. Gern, 2004, The Pediatric infectious disease journal.

Orosomucoid Like 3 (ORMDL3) Supports Rhinovirus Replication in Human Epithelial Cells.

J. Gern, J. Eickhoff, J. W. Tan, 2020, American journal of respiratory cell and molecular biology.

Rhinovirus replication causes RANTES production in primary bronchial epithelial cells.

M. Schroth, J. Gern, P. Frindt, 1999, American journal of respiratory cell and molecular biology.

The Role of Interferons in Driving Susceptibility to Asthma Following Bronchiolitis: Controversies and Research Gaps

N. Papadopoulos, S. Johnston, C. Camargo, 2021, Frontiers in Immunology.

Cockroach allergen component analysis of children with or without asthma and rhinitis in an inner-city birth cohort.

W. Busse, G. O'Connor, L. Bacharier, 2019, The Journal of allergy and clinical immunology.

Glycation of whey protein with dextrans of different molar mass: Effect on immunoglobulin E-binding capacity with blood sera obtained from patients with cow milk protein allergy.

J. Gern, J. Lucey, S. Ikeda, 2018, Journal of dairy science.

Childhood Asthma Incidence, Early and Persistent Wheeze, and Neighborhood Socioeconomic Factors in the ECHO/CREW Consortium.

B. Coull, A. Zanobetti, L. Bacharier, 2022, JAMA pediatrics.

J. Waage, K. Bønnelykke, H. Bisgaard, 2017, American journal of respiratory and critical care medicine.

Fine-mapping studies distinguish genetic risks for childhood- and adult-onset asthma in the HLA region

Matthew C. Altman, M. Stephens, P. Carbonetto, 2022, Genome medicine.

Asthma-associated variants induce IL33 differential expression through a novel regulatory region

Matthew C. Altman, M. Nóbrega, C. Ober, 2020, bioRxiv.

Short- and long-term efficacy of prednisolone for first acute rhinovirus-induced wheezing episode

O. Ruuskanen, C. Camargo, T. Vahlberg, 2014, Journal of Allergy and Clinical Immunology.

Evidence for a Causal Relationship Between Allergic Sensitization and Rhinovirus Wheezing in Early Life

Wai-ming Lee, R. Gangnon, J. Gern, 2012, Pediatrics.

Efficacy and safety of treatment with biologicals (benralizumab, dupilumab, mepolizumab, omalizumab and reslizumab) for severe eosinophilic asthma. A systematic review for the EAACI Guidelines ‐ recommendations on the use of biologicals in severe asthma

T. Casale, N. Papadopoulos, I. Agache, 2020, Allergy.

Efficacy and safety of treatment with dupilumab for severe asthma: A systematic review of the EAACI guidelines—Recommendations on the use of biologicals in severe asthma

G. Canonica, T. Casale, N. Papadopoulos, 2020, Allergy.

Infections and Asthma

J. Gern, R. Lemanske, D. Jackson, 2002, Seminars in respiratory and critical care medicine.

Characterization of regulatory T cells in urban newborns

G. O'Connor, P. Wallace, J. Gern, 2009, Clinical and molecular allergy : CMA.

Farm exposure in early childhood is associated with a lower risk of severe respiratory illnesses.

S. Waring, J. Gern, M. Keifer, 2018, The Journal of allergy and clinical immunology.

Promising Candidates for Prevention of Allergy

J. Gern, 2015 .

Pulmonary 3He magnetic resonance imaging of childhood asthma.

S. Fain, R. Sorkness, R. Cadman, 2013, The Journal of allergy and clinical immunology.

Assessment of wheezing frequency and viral etiology on childhood and adolescent asthma risk

R. Gangnon, J. Gern, R. Lemanske, 2016, Journal of Allergy and Clinical Immunology.

Newborn immunology: relevance to the clinician.

E. Stiehm, D. Lewis, J. Gern, 2006, Current problems in pediatric and adolescent health care.

Mechanisms of virus-induced asthma.

J. Gern, 2003, The Journal of pediatrics.

Multi-omic association study implicates PPP1R13B in DNA methylation-mediated genotype and smoking exposure effects on decreased lung function in urban children

Matthew C. Altman, W. Busse, D. Nicolae, 2022, medRxiv.

Association of ORMDL3 with rhinovirus‐induced endoplasmic reticulum stress and type I Interferon responses in human leucocytes

C. Ober, J. Gern, R. Lemanske, 2017, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Early childhood weight status in relation to asthma development in high-risk children.

R. Gangnon, J. Gern, R. Lemanske, 2010, The Journal of allergy and clinical immunology.

A Functional Genomics Pipeline to Identify High-Value CpG Dinucleotides Related to Allergy or Asthma in the Human Methylome

K. Barnes, R. Mathias, J. Gern, 2022, medRxiv.

Expression Quantitative Trait Locus (eQTL) Fine Mapping of the 17q12–21 Asthma Locus in African American Children: a Cross-Sectional Study

D. Nicolae, A. Levin, G. O'Connor, 2020 .

Effects of dog ownership in early childhood on immune development and atopic diseases

R. Gangnon, J. Gern, R. Lemanske, 2008, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Coronavirus NL63 Illnesses in Infancy are a Risk Factor for Asthma at Age Six

J. Gern, R. Lemanske, M. Evans, 2007, Journal of Allergy and Clinical Immunology.

A polyvalent inactivated rhinovirus vaccine is broadly immunogenic in rhesus macaques

J. Gern, Xiaoyan Lu, K. Roy, 2016, Nature Communications.

50-valent inactivated rhinovirus vaccine is broadly immunogenic in rhesus macaques

J. Gern, Xiaoyan Lu, K. Roy, 2016, bioRxiv.

Association of Rhinovirus Infections with Asthma

W. Busse, J. Gern, 1999, Clinical Microbiology Reviews.

The Role of Childhood Asthma in Obesity Development

F. Perera, A. Alshawabkeh, B. Lester, 2021, Epidemiology.

Infectious triggers of pediatric asthma.

J. Gern, R. Lemanske, 2003, Pediatric clinics of North America.

The role of respiratory viruses in asthma.

W. Busse, J. Gern, E. Dick, 1997, Ciba Foundation symposium.

TLR-7 Stress Signaling in Differentiating and Mature Eosinophils Is Mediated by the Prolyl Isomerase Pin1

J. Gern, J. Malter, Y. Bochkov, 2018, The Journal of Immunology.

Fractional exhaled nitric oxide measurements are most closely associated with allergic sensitization in school-age children.

R. Gangnon, J. Gern, R. Lemanske, 2009, The Journal of allergy and clinical immunology.

NHLBI Workshop Strategic Plan for Pediatric Respiratory Diseases Research An NHLBI Working Group Report

D. Gozal, N. Prabhakar, W. Teague, 2009 .

Maternal microchimerism protects against the development of asthma.

C. Ober, J. Gern, R. Myers, 2013, The Journal of allergy and clinical immunology.

Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma

Scott T. Weiss, Rasika A. Mathias, Oren E. Livne, 2015, Nature Communications.

Inhaled corticosteroid use is associated with increased circulating T regulatory cells in children with asthma

R. Gangnon, J. Gern, R. Lemanske, 2013, Clinical and Molecular Allergy.

Longitudinal data reveal strong genetic and weak non-genetic components of ethnicity-dependent blood DNA methylation levels

D. Nicolae, G. O'Connor, C. Ober, 2018, Epigenetics.

Longitudinal studies at birth and age 7 reveal strong effects of genetic variation on ancestry associated DNA methylation patterns in blood cells from ethnically admixed children

D. Nicolae, G. O'Connor, C. Ober, 2018, bioRxiv.

Calcium-Sensing Receptor Antagonists Abrogate Airway Hyperresponsiveness and Inflammation in Allergic Asthma

J. Gern, F. Rubner, 2015, Pediatrics.

Pyogenic Bacterial Infections in Humans With MyD88 Deficiency

J. Gern, 2009, Pediatrics.

The Children’s Respiratory and Environmental Workgroup (CREW) birth cohort consortium: design, methods, and study population

Carol M Hamilton, Carol M. Hamilton, G. O'Connor, 2019, Respiratory Research.

Antibody Landscapes After Influenza Virus Infection or Vaccination

J. Gern, Ashleigh A. Olson, 2015, Pediatrics.

and Childhood Asthma: Implications for Home Environmental Intervention in Asthma Prevention and Management

A. Custovic, J. Celedón, P. Koutrakis, 2017 .

Rhinovirus C is associated with wheezing and rhinovirus A is associated with pneumonia in hospitalized children in Morocco

Q. Bassat, D. Lehmann, J. Goldblatt, 2016, Journal of medical virology.

Rhinovirus‐C detection in children presenting with acute respiratory infection to hospital in Brazil

J. Gern, D. Fawkner-Corbett, Y. Bochkov, 2011, Journal of medical virology.

Genome Sequences of Rhinovirus B Isolates from Wisconsin Pediatric Respiratory Studies

C. Fraser, S. Liggett, Naomi A. Sengamalay, 2014, Genome Announcements.

Genome Sequences of Rhinovirus C Isolates from Wisconsin Pediatric Respiratory Studies

C. Fraser, S. Liggett, Naomi A. Sengamalay, 2014, Genome Announcements.

Prevalence of and Risk Factors for Human Rhinovirus Infection in Healthy Aboriginal and Non-Aboriginal Western Australian Children

Wai-ming Lee, D. Lehmann, J. Gern, 2012, The Pediatric infectious disease journal.

Rhinoviruses, allergic inflammation, and asthma

M. Gavala, J. Gern, P. Bertics, 2011, Immunological reviews.

Infections and Asthma

J. Gern, R. Lemanske, T. Guilbert, 2010, Pediatric Allergy: Principles and Practice.

Association between human rhinovirus C and severity of acute asthma in children

Wai-ming Lee, J. Goldblatt, J. Gern, 2010, European Respiratory Journal.

Viral respiratory tract infections and asthma: The course ahead

N. Papadopoulos, Richard J Martin, P. Heymann, 2010, Journal of Allergy and Clinical Immunology.

Rhinovirus and the initiation of asthma

J. Gern, 2009, Current opinion in allergy and clinical immunology.

Viral-Induced Wheeze and Asthma Development

J. Gern, A. Coleman, 2015, Allergy, Immunity and Tolerance in Early Childhood.

Genome Sequences of Rhinovirus A Isolates from Wisconsin Pediatric Respiratory Studies

C. Fraser, S. Liggett, Naomi A. Sengamalay, 2014, Genome Announcements.

Rhinoviruses and the onset of asthma

J. Gern, 2019, Rhinovirus Infections.

How rhinovirus infections cause exacerbations of asthma

J. Gern, 2015, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Viral respiratory infections and the oropharyngeal bacterial microbiota in acutely wheezing children

M. Moffatt, J. Gern, D. Cox, 2019, PloS one.

Virus-induced airway hyperresponsiveness and asthma.

W. Busse, R. Sorkness, J. Gern, 1998, American journal of respiratory and critical care medicine.

Innate immune responses to rhinovirus are reduced by the high-affinity IgE receptor in allergic asthmatic children.

R. Gangnon, J. Gern, R. Lemanske, 2012, The Journal of allergy and clinical immunology.

Recurrent severe exacerbations in early life and reduced lung function at school age.

R. Gangnon, J. Gern, R. Lemanske, 2012, The Journal of allergy and clinical immunology.

Bidirectional interactions between viral respiratory illnesses and cytokine responses in the first year of life.

R. Gangnon, J. Gern, R. Lemanske, 2006, The Journal of allergy and clinical immunology.

Persistence of viral RNA in 2 rat strains differing in susceptibility to postbronchiolitis airway dysfunction.

R. Sorkness, J. Gern, R. Lemanske, 2002, The Journal of allergy and clinical immunology.

Development of a Rhinovirus Inoculum Using a Reverse Genetics Approach

Wai-ming Lee, S. Liggett, R. Gangnon, 2018, The Journal of infectious diseases.

Virus/Allergen Interaction in Asthma Exacerbation.

J. Gern, 2015, Annals of the American Thoracic Society.

Nasal lavage VEGF and TNF‐α levels during a natural cold predict asthma exacerbations

N. Jarjour, J. Gern, E. A. Kelly, 2014, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Effects of rhinovirus species on viral replication and cytokine production.

J. Gern, K. Nakagome, M. Evans, 2014, The Journal of allergy and clinical immunology.

Experimental rhinovirus 16 infection in moderate asthmatics on inhaled corticosteroids

S. Johnston, R. Djukanović, J. Gern, 2013, European Respiratory Journal.

Budesonide and formoterol effects on rhinovirus replication and epithelial cell cytokine responses

W. Busse, N. Jarjour, J. Gern, 2013, Respiratory Research.

Interaction between allergy and innate immunity: model for eosinophil regulation of epithelial cell interferon expression.

Wai-ming Lee, N. Jarjour, J. Gern, 2013, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Updates in the Relationship Between Human Rhinovirus and Asthma

J. Gern, W. Kim, 2011, Allergy, asthma & immunology research.

Rhinovirus-associated wheeze during infancy and asthma development.

T. Jartti, J. Gern, 2011, Current respiratory medicine reviews.

Effects of montelukast on patients with asthma after experimental inoculation with human rhinovirus 16.

R. Vrtis, J. Gern, K. Kloepfer, 2011, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Effects of Montelukast in Subjects With Asthma After Experimental Inoculation with Rhinovirus-16

R. Vrtis, J. Gern, K. Kloepfer, 2011 .

Virus/Allergen Interactions and Exacerbations of Asthma

J. Gern, K. Kloepfer, 2010, Immunology and Allergy Clinics of North America.

Interferon- γ Enhances Rhinovirus-Induced RANTES Secretion by Airway Epithelial Cells

M. Schroth, W. Busse, Wai-ming Lee, 2002 .

Rhinovirus respiratory infections and asthma.

J. Gern, 2002, The American journal of medicine.

A rat model of picornavirus-induced airway infection and inflammation

R. Sorkness, J. Gern, R. Lemanske, 2009, Virology Journal.

Detection of rhinovirus RNA in lower airway cells during experimentally induced infection.

W. Busse, N. Jarjour, J. Gern, 1997, American journal of respiratory and critical care medicine.

Rhinovirus enters but does not replicate inside monocytes and airway macrophages.

W. Busse, J. Gern, K. Meyer, 1996, Journal of immunology.

Viral Respiratory Infection and the Link to Asthma

J. Gern, 2008, The Pediatric infectious disease journal.

Cytokine response patterns, exposure to viruses, and respiratory infections in the first year of life.

R. Gangnon, J. Gern, R. Lemanske, 2004, American journal of respiratory and critical care medicine.

Rhinovirus produces nonspecific activation of lymphocytes through a monocyte-dependent mechanism.

W. Busse, R. Vrtis, J. Gern, 1996, Journal of immunology.

R. Gangnon, S. Fain, R. Sorkness, 2015, The Journal of allergy and clinical immunology.

Detection of respiratory syncytial virus or rhinovirus weeks after hospitalization for bronchiolitis and the risk of recurrent wheezing.

C. Camargo, J. Gern, A. Sullivan, 2020, The Journal of infectious diseases.

Early life rhinovirus wheezing, allergic sensitization, and asthma risk at adolescence

R. Gangnon, J. Gern, R. Lemanske, 2016, Journal of Allergy and Clinical Immunology.

Comparison of the Etiology of Viral Respiratory Illnesses in Inner-City and Suburban Infants

Wai-ming Lee, J. Gern, R. Wood, 2012, The Journal of infectious diseases.

The Interactions of Virus Infection and Allergy

W. Busse, J. Gern, G. D. Brooks, 2003 .

Microbiome, Metabolism, and Immunoregulation of Asthma: An American Thoracic Society and National Institute of Allergy and Infectious Diseases Workshop Report

T. Chatila, C. Lozupone, J. Gern, 2022, American journal of respiratory cell and molecular biology.

Detection of Pathogenic Bacteria During Rhinovirus Infection is Associated with Increased Respiratory Symptoms and Exacerbations of Asthma

Wai-ming Lee, R. Gangnon, R. Vrtis, 2014 .

Barnyard microbes and childhood asthma.

J. Gern, 2011, The New England journal of medicine.

Mepolizumab for urban children with exacerbation-prone eosinophilic asthma in the USA (MUPPITS-2): a randomised, double-blind, placebo-controlled, parallel-group trial

Matthew C. Altman, P. Gergen, W. Busse, 2022, The Lancet.

Viral and bacterial infections in the development and progression of asthma.

J. Gern, 2000, The Journal of allergy and clinical immunology.

Effect of Vitamin D3 Supplementation on Severe Asthma Exacerbations in Children With Asthma and Low Vitamin D Levels: The VDKA Randomized Clinical Trial.

M. Cabana, S. Wisniewski, J. Celedón, 2020, JAMA.

Aeroallergen Sensitization, Serum IgE, and Eosinophilia as Predictors of Response to Omalizumab Therapy during the Fall Season among Children with Persistent Asthma.

P. Gergen, W. Busse, J. Gern, 2020, The journal of allergy and clinical immunology. In practice.

Recurrent rhinovirus detections in children following a rhinovirus-induced wheezing exacerbation: A retrospective study.

J. Goldblatt, J. Gern, P. N. Souëf, 2015, International journal of pediatrics and child health.

17q12‐q21 variants interact with early‐life exposures to modify asthma risk in Black children

Matthew C. Altman, G. O'Connor, C. Ober, 2021, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Ligation of intercellular adhesion molecule 3 inhibits GM-CSF production by human eosinophils.

W. Busse, J. Sedgwick, R. Vrtis, 2003, The Journal of allergy and clinical immunology.

R. Gangnon, J. Gern, R. Lemanske, 2006, The Journal of allergy and clinical immunology.

Environmental factors influencing the production of allergic inflammation

W. Busse, J. Gern, R. Lemanske, 2022 .

The hygiene hypothesis revisited.

J. Gern, J. Bufford, 2005, Immunology and allergy clinics of North America.

Eosinophils bind rhinovirus and activate virus-specific T cells.

W. Busse, Wai-ming Lee, J. Sedgwick, 1998, Journal of immunology.

The Role of Rhinoviruses in Virus-Induced Asthma

W. Busse, J. Gern, R. Lemanske, 1998 .

Asthma Association of Rhinovirus Infections with

W. Busse, J. Gern, 1998 .

The effects of rhinovirus infections on allergic airway responses.

W. Busse, J. Gern, 1995, American journal of respiratory and critical care medicine.

Rhinovirus C15 Induces Airway Hyperresponsiveness Via Calcium Mobilization in Airway Smooth Muscle.

S. Liggett, J. Gern, Y. Bochkov, 2020, American journal of respiratory cell and molecular biology.

Allergen challenge in vivo alters rhinovirus-induced chemokine secretion from human airway macrophages.

M. Gavala, J. Gern, P. Bertics, 2014, The Journal of allergy and clinical immunology.

Etiology of asthma exacerbations inchildren: differences from adults

J. Gern, 2007 .

Rhinovirus Replication in Human Macrophages Induces NF-κB-Dependent Tumor Necrosis Factor Alpha Production

S. Johnston, J. Gern, S. Message, 2006, Journal of Virology.

Viral Infections, Cytokine Dysregulation and the Origins of Childhood Asthma and Allergic Diseases

R. Gangnon, J. Gern, R. Lemanske, 2005, The Pediatric infectious disease journal.

Effects of inflammatory cytokines on the permeability of human lung microvascular endothelial cell monolayers and differential eosinophil transmigration.

W. Busse, J. Sedgwick, J. Gern, 2002, The Journal of allergy and clinical immunology.

Do allergies protect against the effects of a rhinovirus cold?

W. Busse, J. Gern, 2000, The Journal of allergy and clinical immunology.

Viruses in asthma.

W. Busse, J. Gern, 1997, The Journal of allergy and clinical immunology.

Challenge in the Airway After Allergen α Receptor Eosinophils and Increased Soluble IL-5 on Airway α Membrane IL-5 Receptor on Human Eosinophils : I . Loss of α Receptor Decreased Expression of Membrane IL-5

Lin Ying Liu, W. Busse, M. Bates, 2002 .

Human airway epithelial cells express a functional IL‐5 receptor

Matthew C. Altman, N. Jarjour, J. Gern, 2020, Allergy.

W. Busse, A. Togias, J. Gern, 1988, Journal of Allergy and Clinical Immunology.

The contributions of allergic sensitization and respiratory pathogens to asthma inception

J. Gern, R. Lemanske, D. Jackson, 2016, Journal of Allergy and Clinical Immunology.

Analysis of tracheal secretions for rhinovirus during natural colds

M. Schroth, J. Gern, E. Simons, 2005, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

Rhinovirus respiratory infections and asthma

J. Gern, 2003 .

Decreased Expression of Membrane IL-5 Receptor α on Human Eosinophils: II. IL-5 Down-Modulates Its Receptor Via a Proteinase-Mediated Process1

Lin Ying Liu, W. Busse, M. Bates, 2002, The Journal of Immunology.

Defining Age-specific Relationships of Respiratory Syncytial Virus and Rhinovirus Species in Hospitalized Children With Acute Wheeze

J. Gern, D. Cox, Guicheng Zhang, 2021, The Pediatric infectious disease journal.

Rhinovirus is the most common virus and rhinovirus-C is the most common species in paediatric intensive care respiratory admissions

J. Gern, D. Cox, Guicheng Zhang, 2018, European Respiratory Journal.

Human rhinovirus species C infection in young children with acute wheeze is associated with increased acute respiratory hospital admissions.

Wai-ming Lee, J. Goldblatt, J. Gern, 2013, American journal of respiratory and critical care medicine.

Association of Rhinovirus C Bronchiolitis and Immunoglobulin E Sensitization During Infancy With Development of Recurrent Wheeze.

C. Camargo, J. Gern, A. Sullivan, 2019, JAMA pediatrics.

Specific patterns of allergic sensitization in early childhood and asthma & rhinitis risk

R. Gangnon, J. Gern, R. Lemanske, 2013, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Serum IL-6: A Biomarker in Childhood Asthma?

W. Busse, G. O'Connor, L. Bacharier, 2020, The Journal of allergy and clinical immunology.

Trajectories of Adiposity Indicators and Association with Asthma and Lung Function in Urban Minority Children.

P. Gergen, G. O'Connor, L. Bacharier, 2021, The Journal of allergy and clinical immunology.

Effects of dog ownership and genotype on immune development and atopy in infancy.

D. Nicolae, C. Ober, R. Gangnon, 2004, The Journal of allergy and clinical immunology.

Proteinase-Mediated Process Down-Modulates Its Receptor Via a on Human Eosinophils: II. IL-5 a Receptor Decreased Expression of Membrane IL-5

Lin Ying Liu, W. Busse, M. Bates, 2002 .

Serum and low-density lipoprotein enhance interleukin-8 secretion by airway epithelial cells.

W. Busse, J. Gern, J. Malter, 2003, American journal of respiratory cell and molecular biology.

Relationships among aeroallergen sensitization, peripheral blood eosinophils, and periostin in pediatric asthma development

R. Gangnon, J. Gern, R. Lemanske, 2017, The Journal of allergy and clinical immunology.

Comparison of rhinovirus A infection in human primary epithelial and HeLa cells.

J. Gern, A. Palmenberg, S. Amineva, 2011, The Journal of general virology.

The spectrum of severe wheezing in childhood☆

J. Gern, 2004, Journal of Allergy and Clinical Immunology.

Asthma diagnosis and treatment Editorial

J. Gern, 2004 .

Rhinovirus colocalizes with CD68- and CD11b-positive macrophages following experimental infection in humans.

Wai-ming Lee, N. Jarjour, J. Gern, 2013, The Journal of allergy and clinical immunology.

Meperidine attenuates the secretion but not the transcription of interleukin 1 beta in human mononuclear leukocytes.

J. Gern, D. McCarthy, P. Hutson, 1998, Nursing research.

Development of nasal allergen challenge with cockroach in children with asthma

W. Busse, A. Togias, A. Sette, 2021, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

Reply.

Matthew C. Altman, J. Gern, M. Altman, 2018, The Journal of allergy and clinical immunology.

Early identification of children likely to develop persistent asthma : atopy is an integral component of the high risk phenotype

A. Boner, A. Custovic, U. Wahn, 2015 .

Synthesis of the allergen ovomucoid by a replicating Mengo virus

J. Gern, A. Mosser, A. Palmenberg, 2006, Archives of Virology.

Genetic variation in immunoregulatory pathways and atopic phenotypes in infancy.

D. Nicolae, C. Ober, R. Gangnon, 2004, The Journal of allergy and clinical immunology.

β-ADRENERGIC AGONIST THERAPY

J. Gern, R. Lemanske, 1993, Immunology and Allergy Clinics of North America.

Isolation of human conjunctival mast cells and epithelial cells: tumor necrosis factor-alpha from mast cells affects intercellular adhesion molecule 1 expression on epithelial cells.

J. Gern, F. Graziano, S. Miller, 1998, Investigative ophthalmology & visual science.

Mechanisms and Treatment of the Diverse Presentations of Acute Wheezing and Asthma.

E. Israel, J. Gern, 2021, The journal of allergy and clinical immunology. In practice.

Biological characteristics and propagation of human rhinovirus-C in differentiated sinus epithelial cells

J. Gern, Y. Bochkov, R. Brockman-Schneider, 2012, Virology.

Human Airway Epithelial Cells Express Functional IL-5 Receptors

J. Gern, S. Esnault, Y. Bochkov, 2016 .

CD14‐DEPENDENT ACTIVATION OF NF‐κB BY FILARIAL PARASITIC SHEATH PROTEINS

J. Gern, S. Miyamoto, K. Narayanan, 2002 .

Heritable vaginal bacteria influence immune tolerance and relate to early-life markers of allergic sensitization in infancy

Kathrine L. Barnes, Casper G Bendixsen, H. Boushey, 2022, Cell reports. Medicine.

Association between CD4(+)CD25(high) T cells and atopy in children.

P. Wallace, R. Gangnon, T. Jartti, 2007, The Journal of allergy and clinical immunology.

Umbilical cord plasma 25‐hydroxyvitamin D concentration and immune function at birth: the Urban Environment and Childhood Asthma study

P. Gergen, G. O'Connor, F. Witter, 2011, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Cord blood vitamin D concentrations are unrelated to atopy and wheeze in 2 diverse birth cohort studies.

P. Gergen, G. O'Connor, C. Camargo, 2015, The Journal of allergy and clinical immunology.

Does azithromycin modify viral load during se- vere respiratory syncytial virus bronchiolitis?

R. Gangnon, J. Gern, R. Lemanske, 2015 .

Lessons learned from birth cohort studies conducted in diverse environments.

J. Gern, R. Lemanske, D. Jackson, 2017, The Journal of allergy and clinical immunology.

Distinct nasal airway bacterial microbiotas differentially relate to exacerbation in pediatric patients with asthma

J. Gern, Andrew H. Liu, S. Lynch, 2019 .

Cord blood sphingolipids are associated with atopic dermatitis and wheeze in the first year of life

Casper G Bendixsen, J. Gern, Rajesh Kumar, 2022, The journal of allergy and clinical immunology. Global.

African-specific alleles modify risk for asthma at the 17q12-q21 locus in African Americans

Matthew C. Altman, C. Rotimi, P. Gergen, 2022, Genome Medicine.

Interferon-gamma enhances rhinovirus-induced RANTES secretion by airway epithelial cells.

M. Schroth, W. Busse, Wai-ming Lee, 2002, American journal of respiratory cell and molecular biology.

Respiratory viruses are associated with serum metabolome among infants hospitalized for bronchiolitis: A multicenter study

C. Camargo, J. Gern, P. Piedra, 2020, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

Peak flow variation in childhood asthma: a three-year analysis.

J. Gern, N. Adkinson, P. Eggleston, 1994, The Journal of allergy and clinical immunology.

Orosomucoid-like 3 Supports Rhinovirus Replication in Human Epithelial Cells

J. Gern, J. Eickhoff, S. Mathur, 2020 .

Serial culture of murine primary airway epithelial cells and ex vivo replication of human rhinoviruses.

J. Gern, R. Brockman-Schneider, S. Amineva, 2008, Journal of immunological methods.

Spirometry and Impulse Oscillometry in Preschool Children: Acceptability and Relationship to Maternal Smoking in Pregnancy.

P. Gergen, G. O'Connor, L. Bacharier, 2018, The journal of allergy and clinical immunology. In practice.

Immune Responses to Rhinoviruses and Asthma: Are We Three Steps Closer to the Door?

J. Gern, 2020, The Journal of allergy and clinical immunology.

Interferon-λ1 and viral wheeze in asthma: a Gothic duality?

J. Gern, 2012, American journal of respiratory and critical care medicine.

Chronic Mucocutaneous Candidiasis in Humans With Inborn Errors of Interleukin-17 Immunity

J. Gern, D. F. McMahon, 2011, Pediatrics.

Do asthma symptoms lag behind cold symptoms in a viral illness?

R. Gangnon, J. Gern, V. Rajamanickam, 2012, The Journal of allergy and clinical immunology.

Modernization of the Medical Sherlock Holmes

W. Busse, J. Gern, 2007, The Journal of infectious diseases.

Is interleukin-10 a "10" in virus-provoked asthma?

W. Busse, J. Gern, 2005, American journal of respiratory and critical care medicine.

Modeling of the human rhinovirus C capsid suggests possible causes for antiviral drug resistance.

J. Gern, A. Palmenberg, J. Sgro, 2014, Virology.

Asthma and infections: is the risk more profound than previously thought?

W. Busse, J. Gern, 2014, The Journal of allergy and clinical immunology.

Enhanced Neutralizing Antibody Responses to Rhinovirus C and Age-Dependent Patterns of Infection.

P. Gergen, W. Busse, C. Ober, 2020, American journal of respiratory and critical care medicine.

Rhinovirus Type in Severe Bronchiolitis and the Development of Asthma

C. Camargo, T. Jartti, J. Gern, 2019, The Journal of Allergy and Clinical Immunology: In Practice.

Rhinovirus C Is Associated With Severe Wheezing and Febrile Respiratory Illness in Young Children

T. Jartti, J. Gern, Y. Bochkov, 2019, The Pediatric infectious disease journal.

Food , drug , insect sting allergy , and anaphylaxis Influence of early-life exposures on food sensitization and food allergy in an inner-city birth cohort

P. Gergen, G. O'Connor, J. Gern, 2014 .

Early exposure to pets: Good or bad?

J. Gern, J. Bufford, 2007, Current allergy and asthma reports.

Inhibition of Rhinovirus Replication In Vitro and In Vivo by Acid-Buffered Saline

J. Gern, A. Mosser, C. Swenson, 2007, The Journal of infectious diseases.

Determinants of sputum neutrophilia after experimental infection with rhinovirus (RV) 16

W. Busse, R. Vrtis, J. Gern, 2004 .

The airway distribution of rhinovirus following an experimental inoculation

W. Busse, R. Vrtis, J. Gern, 2003 .

Respiratory Syncytial Virus Bronchiolitis: Enter the Microbiome.

J. Gern, 2016, American journal of respiratory and critical care medicine.

Lethal Respiratory Disease Associated with Human Rhinovirus C in Wild Chimpanzees, Uganda, 2013

T. Goldberg, R. Wrangham, J. Gern, 2018, Emerging infectious diseases.

Rhinovirus species and clinical characteristics in the first wheezing episode in children

T. Jartti, J. Gern, Y. Bochkov, 2016, Journal of medical virology.

Development of Asthma in Inner-City Children: Possible Roles of MAIT Cells and Variation in the Home Environment

J. Greenbaum, G. O'Connor, A. Gholami, 2018, The Journal of Immunology.

Developmental cytokine response profiles and the clinical and immunologic expression of atopy during the first year of life.

R. Gangnon, J. Gern, R. Lemanske, 2003, The Journal of allergy and clinical immunology.

DNA methylation signatures in airway cells from adult children of asthmatic mothers reflect subtypes of severe asthma

Matthew C. Altman, C. Ober, J. Gern, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Competition among Nasal Bacteria Suggests a Role for Siderophore-Mediated Interactions in Shaping the Human Nasal Microbiota

J. Gern, M. Chevrette, C. Currie, 2018, Applied and Environmental Microbiology.

Bacterial competition mediated by siderophore production among the human nasal microbiota

J. Gern, M. Chevrette, C. Currie, 2018, bioRxiv.

The relationships among immunoglobulin levels, allergic sensitization, and viral respiratory illnesses in early childhood

R. Gangnon, J. Gern, R. Lemanske, 2010, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

The Urban Environment and Childhood Asthma (URECA) birth cohort study: design, methods, and study population

Rosalind J Wright, P. Gergen, W. Busse, 2009, BMC pulmonary medicine.

Parental characteristics, somatic fetal growth, and season of birth influence innate and adaptive cord blood cytokine responses.

Rosalind J Wright, G. O'Connor, Y. Sadovsky, 2009, The Journal of allergy and clinical immunology.

CDHR3 Asthma-Risk Genotype Affects Susceptibility of Airway Epithelium to Rhinovirus C Infections.

C. Ober, J. Gern, R. Lemanske, 2019, American journal of respiratory cell and molecular biology.

Association of citrulline concentration at birth with lower respiratory tract infection in infancy: Findings from a multi-site birth cohort study

J. Gern, T. Hartert, T. Gebretsadik, 2022, Frontiers in Pediatrics.

J. Gern, K. Nakagome, Y. Bochkov, 2020, Allergy.

Relationship of viral infections to wheezing illnesses and asthma

W. Busse, J. Gern, 2002, Nature Reviews Immunology.

Temperature is a powerful promoter of interleukin 2 transcription.

J. Gern, H. Lederman, P. Murphy, 1991, Cytokine.

Asthma as an Outcome: Exploring Multiple Definitions of Asthma across Birth Cohorts in the ECHO Children's Respiratory and Environmental Workgroup (CREW).

Lisa J. Martin, J. Gern, T. Hartert, 2019, The Journal of allergy and clinical immunology.

Children Hospitalized with Rhinovirus Bronchiolitis Have Asthma-Like Characteristics

C. Camargo, J. Gern, S. Clark, 2016, The Journal of Pediatrics.

Etiology of Viral Wheezing Illnesses in Children from Birth to Age 6 Years

Wai-ming Lee, R. Gangnon, J. Gern, 2008 .

Wheezing Rhinovirus Illnesses During Early Childhood and the Subsequent Development of Asthma

R. Gangnon, J. Gern, R. Lemanske, 2008 .

High-Throughput, Sensitive, and Accurate Multiplex PCR-Microsphere Flow Cytometry System for Large-Scale Comprehensive Detection of Respiratory Viruses

David J. Marshall, Michael J. Moser, Edward L. Beaty, 2007, Journal of Clinical Microbiology.

The effect of an experimental rhinovirus 16 infection on bronchial lavage neutrophils.

W. Busse, N. Jarjour, J. Gern, 2000, The Journal of allergy and clinical immunology.

Early‐life home environment and risk of asthma among inner‐city children

Robert A. Wood, Ali A. Faruqi, George T. O'Connor, 2017, The Journal of allergy and clinical immunology.

Protection against atopic diseases by measles--a rash conclusion?

J. Gern, S. Weiss, 2000, Journal of the American Medical Association (JAMA).

Rhinovirus 3C Protease Can Localize in the Nucleus and Alter Active and Passive Nucleocytoplasmic Transport

J. Gern, D. Jans, R. Ghildyal, 2009, Journal of Virology.

Learning from molecular sleuths.

W. Busse, J. Gern, 2009, The Journal of allergy and clinical immunology.

Severity of virus-induced asthma symptoms is inversely related to resolution IFN-λ expression.

N. Jarjour, J. Gern, L. Denlinger, 2015, The Journal of allergy and clinical immunology.

Staphylococcus aureus and Staphylococcus epidermidis Strain Diversity Underlying Pediatric Atopic Dermatitis

J. Gern, Evelyn L. Angulo, 2018, Pediatrics.

Promising candidates for allergy prevention.

J. Gern, 2015, The Journal of allergy and clinical immunology.

Current perspectives Promising candidates for allergy prevention

J. Gern, 2015 .

Rhinovirus Species in Children With Severe Bronchiolitis: Multicenter Cohort Studies in the United States and Finland

C. Camargo, T. Jartti, J. Gern, 2019, The Pediatric infectious disease journal.

Respiratory viruses in young South African children with acute lower respiratory infections and interactions with HIV

David W. Smith, D. Lehmann, J. Goldblatt, 2016, Journal of Clinical Virology.

Production, purification, and capsid stability of rhinovirus C types.

J. Gern, K. Nakagome, A. Palmenberg, 2015, Journal of virological methods.

Propagation of rhinovirus-C strains in human airway epithelial cells differentiated at air-liquid interface.

J. Gern, R. Brockman-Schneider, S. Ashraf, 2015, Methods in molecular biology.

Association Of Specific Human Rhinovirus Strains And Species With Severe Respiratory Illnesses

Wai-ming Lee, R. Gangnon, J. Gern, 2011, ATS 2011.

Allergic Sensitization is a Risk Factor for Rhinovirus Wheezing Illnesses During Early Childhood

R. Gangnon, J. Gern, R. Lemanske, 2010 .

Lower airway rhinovirus burden and the seasonal risk of asthma exacerbation.

Wai-ming Lee, N. Jarjour, R. Sorkness, 2011, American journal of respiratory and critical care medicine.

Nasal Inflammatory Response To Viral Infection In Persons With And Without Asthma

Lin Ying Liu, Wai-ming Lee, N. Jarjour, 2010, ATS 2010.

Rhinovirus-Associated Asthma Exacerbations.

Wai-ming Lee, N. Jarjour, R. Sorkness, 2009, ATS 2009.

New Insights Relating Gasdermin B to the Onset of Childhood Asthma.

Mark W. Craven, C. Ober, J. Gern, 2022, American journal of respiratory cell and molecular biology.

Birth cohorts in asthma and allergic diseases: report of a NIAID/NHLBI/MeDALL joint workshop.

Rosalind J Wright, P. Gergen, M. Cabana, 2014, The Journal of allergy and clinical immunology.

Clinical and Virus Surveillance After the First Wheezing Episode: Special Reference to Rhinovirus A and C Species

T. Jartti, J. Gern, Y. Bochkov, 2017, The Pediatric infectious disease journal.

Daily or intermittent budesonide in preschool children with recurrent wheezing.

M. Schatz, C. Sorkness, L. Bacharier, 2011, The New England journal of medicine.

Asthma Management in Children.

P. Gergen, J. Gern, E. Matsui, 2022, The journal of allergy and clinical immunology. In practice.

Expression quantitative trait locus fine mapping of the 17q12-21 asthma locus in African American children: a genetic association and gene expression study.

Brent F. Olson, Kathrine L. Barnes, Casper G Bendixsen, 2020, The Lancet. Respiratory medicine.

Efficacy of inhaled salbutamol with and without prednisolone for first acute rhinovirus‐induced wheezing episode

T. Vahlberg, T. Jartti, J. Gern, 2020, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Distinguishing characteristics of difficult-to-control asthma in inner-city children and adolescents.

P. Gergen, W. Busse, A. Togias, 2016, The Journal of allergy and clinical immunology.

Weekly monitoring of children with asthma for infections and illness during common cold seasons

Wai-ming Lee, J. Gern, W. Kim, 2010, Journal of Allergy and Clinical Immunology.

Picornavectors. Viruses That Spread Bacteria.

J. Gern, 2017, American journal of respiratory and critical care medicine.

Evolving concepts in how viruses impact asthma: A Work Group Report of the Microbes in Allergy Committee of the American Academy of Allergy, Asthma Immunology

Matthew C. Altman, P. Heymann, J. Gern, 2020 .

Association of rhinovirus species with nasopharyngeal metabolome in bronchiolitis infants: A multicenter study

C. Camargo, J. Gern, P. Piedra, 2020, Allergy.

Detection of pathogenic bacteria during rhinovirus infection is associated with increased respiratory symptoms and asthma exacerbations.

Ronald E Gangnon, Daniel J Jackson, Wai-ming Lee, 2014, The Journal of allergy and clinical immunology.

Association of respiratory allergy, asthma, and expression of the SARS-CoV-2 receptor ACE2

P. Gergen, W. Busse, G. O'Connor, 2020, Journal of Allergy and Clinical Immunology.

Detection of respiratory syncytial virus and rhinovirus in healthy infants

C. Camargo, J. Gern, P. Piedra, 2015, BMC Research Notes.

EAACI Biologicals Guidelines—Recommendations for severe asthma

G. Canonica, T. Casale, N. Papadopoulos, 2020, Allergy.

IFNG genotype and sex interact to influence the risk of childhood asthma.

C. Ober, R. Gangnon, D. A. Loisel, 2011, The Journal of allergy and clinical immunology.

Evolving Concepts in how Viruses Impact Asthma.

Matthew C. Altman, P. Heymann, J. Gern, 2020, The Journal of allergy and clinical immunology.

Ecological and individual data both indicate that influenza inhibits rhinovirus infection

J. Gern, K. Kloepfer, 2020, Proceedings of the National Academy of Sciences.

Early life origins of asthma.

W. Busse, J. Gern, R. Lemanske, 1999, The Journal of clinical investigation.

Quantitative detection of messenger RNA by solution hybridization and enzyme immunoassay.

J. Gern, F. Coutlée, H. Lederman, 1990, The Journal of biological chemistry.

The Antibacterial Lectin RegIII-Gamma Promotes the Spatial Segregation of Microbiota and Host in the Intestine

J. Gern, 2012, Pediatrics.

Multi-omic association study identifies DNA methylation-mediated genotype and smoking exposure effects on lung function in children living in urban settings

Matthew C. Altman, W. Busse, D. Nicolae, 2023, PLoS genetics.

US Childhood Asthma Incidence Rate Patterns From the ECHO Consortium to Identify High-Risk Groups for Primary Prevention.

F. Gilliland, M. Karagas, A. Litonjua, 2021, JAMA pediatrics.

Association of Severe Bronchiolitis during Infancy with Childhood Asthma Development: An Analysis of the ECHO Consortium

Rosalind J Wright, A. Alshawabkeh, J. Stanford, 2022, Biomedicines.

Association between rhinovirus species and nasopharyngeal microbiota in infants with severe bronchiolitis

C. Camargo, J. Gern, P. Piedra, 2019, Journal of Allergy and Clinical Immunology.

Trajectories of childhood immune development and respiratory health relevant to asthma and allergy

M. Inouye, A. Custovic, S. Johnston, 2018, eLife.

Respiratory Virus Shedding in a Cohort of On-Duty Healthcare Workers Undergoing Prospective Surveillance

K. Edwards, T. Talbot, J. Gern, 2013, Infection Control & Hospital Epidemiology.

The ABCs of Rhinoviruses, Wheezing, and Asthma

J. Gern, 2010, Journal of Virology.

Management of asthma in childhood: study protocol of a systematic evidence update by the Paediatric Asthma in Real Life (PeARL) Think Tank

D. Price, A. Sheikh, H. Zar, 2021, BMJ Open.

Vesiculopustular eruption of ulcerative colitis.

J. Gern, N. Fenske, F. Vasey, 1983, Archives of dermatology.

Simvastatin attenuates rhinovirus‐induced interferon and CXCL10 secretion from monocytic cells in vitro

A. Audhya, J. Gern, P. Bertics, 2014, Journal of leukocyte biology.

Evaluation of a Multiplexed PCR Assay for Detection of Respiratory Viral Pathogens in a Public Health Laboratory Setting

Wai-ming Lee, M. Moser, J. Gern, 2007, Journal of Clinical Microbiology.

Gerda Harms , Edward a Public Health Laboratory Setting Detection of Respiratory Viral Pathogens in Evaluation of a Multiplexed PCR Assay

Wai-ming Lee, M. Moser, J. Gern, 2007 .

The role of T regulatory cells in asthma.

J. Gern, C. Seroogy, 2005, The Journal of allergy and clinical immunology.

Randomized trial of omalizumab (anti-IgE) for asthma in inner-city children.

P. Gergen, W. Busse, A. Togias, 2011, The New England journal of medicine.

Classical Pyoderma Gangrenosum Associated with Abnormal Neutrophil Oxidative Burst

J. Gern, C. Seroogy, R. Viswanathan, 2012 .

Antiinflammatory Activity of IVIG Mediated through the Inhibitory FC Receptor

J. Gern, 2002 .

Airway Microbiota Dynamics Uncover a Critical Window for Interplay of Pathogenic Bacteria and Allergy in Childhood Respiratory Disease

Stephen C. Watts, M. Inouye, S. Johnston, 2018, Cell Host & Microbe.

Dynamics of the upper airway microbiome in the pathogenesis of asthma-associated persistent wheeze in preschool children

Stephen C. Watts, M. Inouye, S. Johnston, 2017, bioRxiv.

Molecular mechanisms in allergy and clinical immunology

R. Sorkness, J. Gern, R. Lemanske, 2005 .

A Review of Evidence Supporting the American Academy of Pediatrics Recommendation for Prescribing Cephalosporin Antibiotics for Penicillin-Allergic Patients

J. Gern, 2006, Pediatrics.

Simultaneous outbreaks of respiratory disease in wild chimpanzees caused by distinct viruses of human origin

J. Mitani, T. Goldberg, R. Wrangham, 2019, Emerging microbes & infections.

Effectiveness of intensive nurse case management in decreasing vertical transmission of human immunodeficiency virus infection in Wisconsin.

J. Gern, M. Chusid, P. Havens, 1997, The Pediatric infectious disease journal.

Altered transcriptional and chromatin responses to rhinovirus in bronchial epithelial cells from adults with asthma

D. Nicolae, M. Nóbrega, N. Sakabe, 2020, Communications Biology.

Altered transcriptional and chromatin responses to rhinovirus in bronchial epithelial cells from adults with asthma

D. Nicolae, M. Nóbrega, C. Ober, 2020, Communications Biology.

Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function.

Ying Sun, Carole Ober, Dan L Nicolae, 2008, The New England journal of medicine.

Whole-Genome Sequencing of Individuals from a Founder Population Identifies Candidate Genes for Asthma

Catarina D. Campbell, J. Shendure, Niklas Krumm, 2014, PloS one.

Role of viral infections in the development and exacerbation of asthma in children

T. Jartti, J. Gern, 2017, Journal of Allergy and Clinical Immunology.

Rhinovirus-induced modulation of gene expression in bronchial epithelial cells from subjects with asthma

S. Keleş, N. Jarjour, J. Gern, 2010, Mucosal Immunology.

Daniel J. Jackson, James E. Gern, J. Gern, 2015, Proceedings of the National Academy of Sciences.

Multi-omics colocalization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus

Matthew C. Altman, D. Nicolae, J. Celedón, 2021, Genome medicine.

Global DNA methylation changes spanning puberty are near predicted estrogen-responsive genes and enriched for genes involved in endocrine and immune processes

C. Ober, J. Gern, R. Lemanske, 2018, Clinical Epigenetics.

Multi-omics colocalization with genome-wide association studies reveals a context-specific genetic mechanism at a childhood onset asthma risk locus

Matthew C. Altman, D. Nicolae, C. Ober, 2019, Genome Medicine.

Meta-analysis of Genome-wide Association Studies of Asthma In Ethnically Diverse North American Populations

Ryan D. Hernandez, Christopher R. Gignoux, L. Liang, 2011, Nature Genetics.

Single-Cell Mapping of Progressive Fetal-to-Adult Transition in Human Naive T Cells.

Chun Jimmie Ye, Charles C. Kim, M. Sirota, 2021, Cell reports.

Effects of early-life exposure to allergens and bacteria on recurrent wheeze and atopy in urban children.

Diane R Gold, Christine C Johnson, William W Busse, 2014, The Journal of allergy and clinical immunology.

Asthma outcomes: exacerbations.

H. Boushey, C. Camargo, W. Teague, 2012, The Journal of allergy and clinical immunology.

Pathways through which asthma risk factors contribute to asthma severity in inner-city children.

P. Gergen, W. Busse, G. O'Connor, 2016, The Journal of allergy and clinical immunology.

Nasopharyngeal microbiota composition of children is related to the frequency of upper respiratory infection and acute sinusitis

Ali A. Faruqi, J. Gern, C. Santee, 2016, Microbiome.

Development of a standardized approach for environmental microbiota investigations related to asthma development in children.

H. Boushey, J. Gern, S. Lynch, 2012, Journal of Microbiological Methods.

FUT2–ABO epistasis increases the risk of early childhood asthma and Streptococcus pneumoniae respiratory illnesses

T. Werge, T. Hansen, O. Pedersen, 2020, Nature Communications.

Loss of regulatory capacity in T regulatory cells upon rhinovirus infection.

N. Papadopoulos, S. Johnston, C. Akdis, 2021, The Journal of allergy and clinical immunology.

Asthma-associated genetic variants induce IL33 differential expression through an enhancer-blocking regulatory region

Matthew C. Altman, M. Nóbrega, C. Ober, 2021, Nature Communications.

Asthma-associated genetic variants induce IL33 differential expression through a novel regulatory region.

Matthew C. Altman, M. Nóbrega, C. Ober, 2020 .

Human monocytic cells direct the robust release of CXCL10 by bronchial epithelial cells during rhinovirus infection

M. Bates, J. Gern, P. Bertics, 2010, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Variation in ITGB3 is associated with asthma and sensitization to mold allergen in four populations.

C. Ober, L. Weiss, J. Gern, 2005, American journal of respiratory and critical care medicine.

Rhinovirus wheezing illness and genetic risk of childhood-onset asthma.

Hans Bisgaard, Carole Ober, Dan L Nicolae, 2013, The New England journal of medicine.

Inducible expression quantitative trait locus analysis of the MUC5AC gene in asthma in urban populations of children.

Scott R. Presnell, Matthew C. Altman, Kaitlin J. Flynn, 2021, The Journal of allergy and clinical immunology.

Chromosome 17q12-21 Variants are Associated with Multiple Wheezing Phenotypes in Childhood.

D. Nicolae, G. O'Connor, C. Ober, 2021, American journal of respiratory and critical care medicine.

Viruses associated with ill health in wild chimpanzees

J. Mitani, T. Goldberg, R. Wrangham, 2022, American journal of primatology.

Impact of COVID-19 on Pediatric Asthma: Practice Adjustments and Disease Burden

H. Zar, O. Kalayci, N. Papadopoulos, 2020, The Journal of Allergy and Clinical Immunology: In Practice.

A Diverse Group of Previously Unrecognized Human Rhinoviruses Are Common Causes of Respiratory Illnesses in Infants

Wai-ming Lee, T. Jartti, J. Gern, 2007, PloS one.

Improved Molecular Typing Assay for Rhinovirus Species A, B, and C

J. Gern, M. Evans, Y. Bochkov, 2014, Journal of Clinical Microbiology.

The marble test for gastric outlet obstruction in chronic granulomatous disease.

J. Gern, W. Nauseef, E. Simons, 2003, The Journal of allergy and clinical immunology.

Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients With Wiskott-Aldrich Syndrome

J. Gern, A. Coleman, 2014, Pediatrics.

Human antibodies neutralize enterovirus D68 and protect against infection and paralytic disease

M. Rossmann, I. Georgiev, T. Klose, 2020, Science Immunology.

Mutations in VP1 and 3A proteins improve binding and replication of rhinovirus C15 in HeLa-E8 cells.

J. Gern, A. Palmenberg, Y. Bochkov, 2016, Virology.

Clinical and molecular features of human rhinovirus C.

J. Gern, Y. Bochkov, 2012, Microbes and infection.

Integrin beta 3 genotype influences asthma and allergy phenotypes in the first 6 years of life.

D. Nicolae, C. Ober, I. Ostrovnaya, 2007, The Journal of allergy and clinical immunology.

Bronchiolitis to asthma: a review and call for studies of gene-virus interactions in asthma causation.

Paul E Moore, J. Gern, T. Hartert, 2007, American journal of respiratory and critical care medicine.

Club Cell TRPV4 Serves as a Damage Sensor Driving Lung Allergic Inflammation.

Mengyao Niu, C. Ober, M. Freeman, 2020, Cell host & microbe.

Club cell TRPV4 as a damage sensor driving lung allergic inflammation

C. Ober, M. Freeman, N. Jarjour, 2019, bioRxiv.

Toll‐like receptor 3 blockade in rhinovirus‐induced experimental asthma exacerbations: A randomized controlled study

V. Backer, S. Johnston, B. Lipworth, 2017, The Journal of allergy and clinical immunology.

Report from the National Institute of Allergy and Infectious Diseases workshop on “Atopic dermatitis and the atopic march: Mechanisms and interventions”

H. Kong, W. Busse, S. Ziegler, 2019, The Journal of allergy and clinical immunology.

Relationships among specific viral pathogens, virus‐induced interleukin‐8, and respiratory symptoms in infancy

Kunling Shen, M. Kosorok, J. Gern, 2002, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

A SINGLE ATAXIA TELANGIECTASIA GENE WITH A PRODUCT SIMILAR TO PI-3 KINASE

J. Gern, 1996, Pediatrics.

Effects of viral respiratory infections on lung development and childhood asthma

R. Sorkness, J. Gern, R. Lemanske, 2005, Journal of Allergy and Clinical Immunology.

Double-stranded RNA induces the synthesis of specific chemokines by bronchial epithelial cells.

W. Busse, J. Gern, Delores A. French, 2003, American journal of respiratory cell and molecular biology.

Dual role of the miR‐146 family in rhinovirus‐induced airway inflammation and allergic asthma exacerbation

S. Johnston, J. Wengel, J. Gern, 2021, Clinical and translational medicine.

Dynamics of Bacterial Colonization With Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis During Symptomatic and Asymptomatic Viral Upper Respiratory Tract Infection

J. Gern, J. Eickhoff, S. Lynch, 2017, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Strategic plan for pediatric respiratory diseases research: an NHLBI working group report.

Rosalind J Wright, G. Redding, D. Gozal, 2009, Proceedings of the American Thoracic Society.

Strategic plan for pediatric respiratory diseases research: An NHLBI working group report

Rosalind J Wright, G. Redding, D. Gozal, 2009, Pediatric pulmonology.

Association of respiratory allergy, asthma, and expression of the SARS-CoV-2 receptor ACE2

P. Gergen, W. Busse, G. O'Connor, 2020, Journal of Allergy and Clinical Immunology.

Longitudinal Phenotypes of Respiratory Health in a High‐Risk Urban Birth Cohort

P. Gergen, H. Boushey, G. O'Connor, 2019, American journal of respiratory and critical care medicine.

Cockroach-induced IL9, IL13, and IL31 expression and the development of allergic asthma in urban children.

Matthew C. Altman, W. Busse, A. Togias, 2021, The Journal of allergy and clinical immunology.

Preseasonal treatment with either omalizumab or an inhaled corticosteroid boost to prevent fall asthma exacerbations.

P. Gergen, W. Busse, A. Togias, 2015, The Journal of allergy and clinical immunology.

Seasonal Airway Microbiome and Transcriptome Interactions Promote Childhood Asthma Exacerbations.

Scott R. Presnell, Matthew C. Altman, Kaitlin J. Flynn, 2022, The Journal of allergy and clinical immunology.

Microbial volatile communication in human organotypic lung models

Yasmín R Álvarez-García, Mengyao Niu, D. Beebe, 2017, Nature Communications.

Developmental patterns in the nasopharyngeal microbiome during infancy are associated with asthma risk

M. Inouye, K. Holt, Kristine E. Lee, 2020, Journal of Allergy and Clinical Immunology.

Effect of Variation in CHI 3 L 1 on Serum YKL-40 Level , Risk of Asthma , and Lung Function

K. Deichmann, D. Nicolae, A. Heinzmann, 2008 .

Enhanced plasmacytoid dendritic cell antiviral responses after omalizumab

W. Busse, A. Togias, J. Gern, 2017, The Journal of allergy and clinical immunology.

830 A 3-year-old boy with ZAP-70 deficiency, thrombocytopenia and ulcerative colitis

J. Gern, D. E. Parry, S. Horowitz, 1996 .

THE EARLY-LIFE NASOPHARYNGEAL MICROBIOME INTERACTS WITH ALLERGIC AND NON-ALLERGIC MECHANISMS OF CHILDHOOD WHEEZE

M. Inouye, K. Holt, P. Sly, 2019 .

Meditation or Exercise for Preventing Acute Respiratory Infection: A Randomized Controlled Trial

Roger L. Brown, C. Coe, J. Gern, 2012, The Annals of Family Medicine.

Integrated-omics endotyping of infants with rhinovirus bronchiolitis and risk of childhood asthma.

J. Celedón, C. Camargo, J. Gern, 2020, The Journal of allergy and clinical immunology.

Endotypes of difficult-to-control asthma in inner-city African American children

W. Busse, A. Togias, J. Gern, 2017, PloS one.

Non-parametric mixture models identify trajectories of childhood immune development relevant to asthma and allergy

M. Inouye, A. Custovic, S. Johnston, 2017, bioRxiv.

Relationships among environmental exposures, cord blood cytokine responses, allergy, and wheeze at 1 year of age in an inner-city birth cohort (Urban Environment and Childhood Asthma study).

P. Gergen, J. Gern, D. Gold, 2011, The Journal of allergy and clinical immunology.

The influence of processing factors and non‐atopy‐related maternal and neonate characteristics on yield and cytokine responses of cord blood mononuclear cells

R. Gangnon, J. Gern, R. Lemanske, 2007, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Rhinovirus species and clinical features in children hospitalised with pneumonia from Mozambique

Q. Bassat, D. Lehmann, M. Lanaspa, 2016, Tropical medicine & international health : TM & IH.

Human Rhinovirus is the Most Commonly Identified Respiratory Virus in Children 1 Hospitalized with Pneumonia from Mozambique 2 3

Q. Bassat, D. Lehmann, M. Lanaspa, 2016 .

Wisconsin Upper Respiratory Symptom Survey for Kids: Validation of an Illness-specific Quality of Life Instrument

Roger L. Brown, J. Gern, E. Wald, 2021, Pediatric Research.

Unconjugated bilirubin is associated with protection from early-life wheeze and childhood asthma.

C. Ober, J. Gern, T. Hartert, 2021, The Journal of allergy and clinical immunology.

Experimental rhinovirus infection induces an antiviral response in circulating B cells which is dysregulated in patients with asthma

N. Papadopoulos, S. Johnston, C. Akdis, 2021, Allergy.

Early identification of atopy in the prediction of persistent asthma in children

Adnan Custovic, Peter D Sly, Harald Renz, 2008, The Lancet.

Molecular modeling, organ culture and reverse genetics for a newly identified human rhinovirus C

Wai-ming Lee, S. Liggett, N. Jarjour, 2011, Nature Medicine.

The Environmental Influences on Child Health Outcomes (ECHO)-Wide Cohort

Emily A. Knapp, Emily A Knapp, Casper G Bendixsen, 2023, American journal of epidemiology.

The association between seasonal asthma exacerbations and viral respiratory infections in a pediatric population receiving inhaled corticosteroid therapy with or without long-acting beta-adrenoceptor agonist: A randomized study☆

C. Prazma, J. Gern, S. Weinstein, 2015, Respiratory Medicine.

Association of Mold Levels in Urban Children's Homes with Difficult-to-Control Asthma.

W. Busse, L. Bacharier, J. Gern, 2021, The Journal of allergy and clinical immunology.

Maternal Stress and Depression are Associatedwith Respiratory Phenotypes in Urban Children.

P. Gergen, G. O'Connor, L. Bacharier, 2021, The Journal of allergy and clinical immunology.

Effects of Omalizumab on Rhinovirus Infections, Illnesses, and Exacerbations of Asthma

W. Busse, A. Togias, J. Gern, 2017, American journal of respiratory and critical care medicine.

Relationships among Maternal Stress and Depression, Type 2 Responses, and Recurrent Wheezing at Age 3 Years in Low‐Income Urban Families

Rosalind J Wright, J. Gern, R. Wood, 2017, American journal of respiratory and critical care medicine.

Transcriptome networks identify mechanisms of viral and nonviral asthma exacerbations in children

Scott R. Presnell, Elizabeth Whalen, Daniel J Jackson, 2019, Nature Immunology.

PEDIATRIC ALLERGY

J. Gern, R. Lemanske, 1999, Immunology and Allergy Clinics of North America.

Influenza: A Bad Illness for Children With (or Without) Asthma.

J. Gern, Job Wilson, 2023, The journal of allergy and clinical immunology. In practice.

Increased H1N1 infection rate in children with asthma.

Wai-ming Lee, R. Gangnon, R. Vrtis, 2012, American journal of respiratory and critical care medicine.

Insulin desensitization with insulin lispro and an insulin pump in a 5-year-old child.

J. Gern, S. Eapen, E. Connor, 2000, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Association of rhinovirus species with common cold and asthma symptoms and bacterial pathogens.

R. Gangnon, R. Vrtis, J. Gern, 2017, The Journal of allergy and clinical immunology.

Community-acquired rhinovirus infection is associated with changes in the airway microbiome.

S. Janga, Wai-ming Lee, J. Gern, 2017, The Journal of allergy and clinical immunology.

Decreased lung function after preschool wheezing rhinovirus illnesses in children at risk to develop asthma

R. Gangnon, J. Gern, R. Lemanske, 2011, Journal of Allergy and Clinical Immunology.

The infant airway microbiome in health and disease impacts later asthma development

M. Inouye, S. Johnston, K. Holt, 2014, bioRxiv.

Rothia from the Human Nose Inhibit Moraxella catarrhalis Colonization with a Secreted Peptidoglycan Endopeptidase

R. Vrtis, J. Gern, C. Currie, 2023, mBio.

Respiratory health, allergies, and the farm environment: design, methods and enrollment in the observational Wisconsin Infant Study Cohort (WISC): a research proposal

Brent F. Olson, Kathrine L. Barnes, Casper G Bendixsen, 2019, BMC Research Notes.

Associations between outdoor air pollutants and non-viral asthma exacerbations and airway inflammatory responses in children and adolescents living in urban areas in the USA: a retrospective secondary analysis

Gurjit K. Khurana, Matthew C. Altman, P. Gergen, 2023, The Lancet. Planetary health.

Microbial volatile communication in human organotypic lung models

Yasmín R Álvarez-García, Mengyao Niu, D. Beebe, 2017, Nature Communications.

Rhinovirus Infections and Their Roles in Asthma: Etiology and Exacerbations.

J. Gern, D. Jackson, 2022, The journal of allergy and clinical immunology. In practice.

The Associations of Maternal Health Characteristics, Newborn Metabolite Concentrations, and Child Body Mass Index among US Children in the ECHO Program

Pingsheng Wu, J. Gern, T. Hartert, 2023, Metabolites.

Depression, anxiety, and dermatologic quality of life in adolescents with atopic dermatitis.

J. Gern, G. Rogers, M. Essex, 2011, The Journal of allergy and clinical immunology.

Age at First Introduction of Cow Milk Products and Other Food Products in Relation to Infant Atopic Manifestations in the First 2 Years of Life: The KOALA Birth Cohort Study

J. Gern, Jaime P Olenec, 2009, Pediatrics.

Rhinovirus infection preferentially increases lower airway responsiveness in allergic subjects.

W. Busse, J. Gern, C. Swenson, 1997, American journal of respiratory and critical care medicine.

Rationale and methods for a trial assessing placebo, echinacea, and doctor-patient interaction in the common cold.

Kerry Bone, Betty Chewning, Roger Brown, 2007, Explore.

Evaluating the Effects of Farm Exposure on Infant Gut Microbiome: 906

Kathrine L. Barnes, Casper G Bendixsen, J. Gern, 2019, Journal of Allergy and Clinical Immunology.

Endotype of Allergic Asthma with Airway Obstruction in Urban Children.

Scott R. Presnell, Matthew C. Altman, P. Gergen, 2021, The Journal of allergy and clinical immunology.

Pediatric Asthma Incidence Rates in the United States from 1980-2017.

Lisa J. Martin, J. Gern, T. Hartert, 2021, The Journal of allergy and clinical immunology.

Phenotype-directed Therapy with Mepolizumab for Urban Children with Exacerbation-Prone Asthma

P. Gergen, W. Busse, C. Sorkness, 2022, Journal of Allergy and Clinical Immunology.

Transcriptome networks identify mechanisms of viral and nonviral asthma exacerbations in children

Scott R. Presnell, Matthew C. Altman, P. Gergen, 2019, Nature Immunology.

Clinical Features, Virus Identification, and Sinusitis as a Complication of Upper Respiratory Tract Illness in Children Ages 4-7 Years

M. Lindstrom, J. Gern, S. Lynch, 2016, The Journal of Pediatrics.

Patterns of Farm Exposure are Associated with Reduced Incidence of Atopic Dermatitis in Early Life.

Brent F. Olson, Kathrine L. Barnes, Casper G Bendixsen, 2020, The Journal of allergy and clinical immunology.

Nasopharyngeal microbiota composition of children is related to the frequency of upper respiratory infection and acute sinusitis

J. Gern, C. Santee, S. Lynch, 2016, Microbiome.

Relation between stress and cytokine responses in inner-city mothers.

Rosalind J Wright, J. Gern, R. Wood, 2015, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Patterns of immune development in urban preschoolers with recurrent wheeze and/or atopy

P. Gergen, G. O'Connor, L. Bacharier, 2017, The Journal of allergy and clinical immunology.

Genetic associations with viral respiratory illnesses and asthma control in children

D. Nicolae, T. Ahluwalia, K. Bønnelykke, 2016, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Viral Infections and Associated Factors That Promote Acute Exacerbations of Asthma

J. Gern, Chang-Keun Kim, Z. Callaway, 2017, Allergy, asthma & immunology research.

Rhinitis in children and adolescents with asthma: Ubiquitous, difficult to control, and associated with asthma outcomes

P. Gergen, W. Busse, A. Togias, 2019, The Journal of allergy and clinical immunology.

Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB.

Matthew C. Altman, T. Werge, T. Hansen, 2022, The Journal of allergy and clinical immunology.

Epigenome‐wide analysis links SMAD3 methylation at birth to asthma in children of asthmatic mothers

A. Custovic, C. Ober, A. Simpson, 2017, The Journal of allergy and clinical immunology.

Rhinovirus C targets ciliated airway epithelial cells

J. Gern, A. Palmenberg, Y. Bochkov, 2017, Respiratory Research.

Virus/Allergen Interactions in Asthma

M. Gavala, J. Gern, H. Bashir, 2013, Current Allergy and Asthma Reports.

Ensemble Analysis Identifies Nasal 15-Keto-PGE2 as a Predictor of Recovery in Experimental Rhinovirus Colds.

Kristine E. Lee, J. Gern, L. Denlinger, 2021, The Journal of infectious diseases.

Increased H1N1 Infection Rate in Asthmatic Children

Wai-ming Lee, R. Gangnon, R. Vrtis, 2011 .

ErrataAllele-Specific Targeting of microRNAs to HLA-G and Risk of Asthma

D. Nicolae, C. Ober, G. Randall, 2008 .

Gene-environment interaction effects on the development of immune responses in the 1st year of life.

D. Nicolae, C. Ober, I. Ostrovnaya, 2005, American journal of human genetics.

Nasopharyngeal metatranscriptome profiles of infants with bronchiolitis and risk of childhood asthma: a multicentre prospective study

E. Castro-Nallar, M. Pérez‐Losada, C. Camargo, 2021, European Respiratory Journal.

Detection of viral and bacterial pathogens in acute respiratory infections

Roger L. Brown, R. Vrtis, J. Gern, 2013, Journal of Infection.

Resource The Infant Nasopharyngeal Microbiome Impacts Severity of Lower Respiratory Infection and Risk of Asthma Development Graphical

M. Inouye, S. Johnston, K. Holt, 2015 .

Recent Clinical Isolates of Enterovirus D68 Have Increased Replication and Induce Enhanced Epithelial Immune Response Compared to the Prototype Fermon Strain

J. Gern, M. Evans, Y. Bochkov, 2023, Viruses.

A new model of wheezing severity in young children using the validated ISAAC wheezing module: A latent variable approach with validation in independent cohorts

J. Gern, T. Hartert, T. Gebretsadik, 2018, PloS one.

The Back to School asthma study: the effect of montelukast on asthma burden when initiated prophylactically at the start of the school year.

M. Sears, J. Gern, J. Edelman, 2010, Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology.

Rhinovirus C Causes Heterogeneous Infection and Gene Expression in Airway Epithelial Cell Subsets.

C. Kendziorski, J. Gern, Y. Bochkov, 2023, Mucosal immunology.

Interactions between the frequency of viral infections and IFN-γ production in the first year of life

R. Gangnon, J. Gern, R. Lemanske, 2003 .

Siblings, daycare, and culture-confirmed viral respiratory infections in the first year of life

R. Gangnon, J. Gern, R. Lemanske, 2003 .

Protection from asthma in a high-risk birth cohort by attenuated P2X(7) function.

R. Gangnon, J. Gern, L. Denlinger, 2012, The Journal of allergy and clinical immunology.

Standardization and performance evaluation of mononuclear cell cytokine secretion assays in a multicenter study

H. Sampson, M. T. de la Morena, J. Gern, 2006, BMC Immunology.

Single-Cell Mapping of Progressive Fetal-to-Adult Transition in Human Naive T Cells

Chun Jimmie Ye, Charles C. Kim, M. Sirota, 2020, Cell reports.

Expression patterns of atopic eczema and respiratory illnesses in a high-risk birth cohort.

R. Gangnon, J. Gern, R. Lemanske, 2010, The Journal of allergy and clinical immunology.

Reply.

Matthew C. Altman, J. Gern, 2019, The Journal of allergy and clinical immunology.

Prednisolone for the first rhinovirus‐induced wheezing and 4‐year asthma risk: A randomized trial

O. Ruuskanen, C. Camargo, T. Vahlberg, 2017, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

Identification of amino acids in the HA of H3 influenza viruses that determine infectivity levels in primary swine respiratory epithelial cells.

J. Gern, M. Suresh, Marc G. Busch, 2008, Virus research.

Retention strategies and predictors of attrition in an urban pediatric asthma study

J. Gern, C. Visness, Bernadette Adams, 2010, Clinical trials.

Racial and geographic variation in effects of maternal education and neighborhood-level measures of socioeconomic status on gestational age at birth: Findings from the ECHO cohorts

Rosalind J Wright, F. Perera, C. Camargo, 2021, PloS one.

Asthma is associated with carotid arterial injury in children: The Childhood Origins of Asthma (COAST) Cohort

C. Mitchell, J. Gern, J. Stein, 2018, PloS one.

Opportunities for understanding the COVID-19 pandemic and child health in the United States: the Environmental influences on Child Health Outcomes (ECHO) program

Courtney K. Blackwell, J. Schweitzer, A. Ferrara, 2023, Frontiers in Pediatrics.

Serial viral infections in infants with recurrent respiratory illnesses

Wai-ming Lee, T. Jartti, J. Gern, 2008, European Respiratory Journal.

Children Hospitalized with Rhinovirus Bronchiolitis Have Asthma-Like Characteristics

C. Camargo, J. Gern, S. Clark, 2016, The Journal of Pediatrics.

Weekly monitoring of children with asthma for infections and illness during common cold seasons

Wai-ming Lee, J. Gern, W. Kim, 2010, Journal of Allergy and Clinical Immunology.

A distributed geospatial approach to describe community characteristics for multisite studies

Antonella Zanobetti, Fernando D. Martinez, Cole Brokamp, 2021, Journal of Clinical and Translational Science.

Rhinovirus infection induces secretion of endothelin-1 from airway epithelial cells in both in vitro and in vivo models

J. Gern, N. Bartlett, J. Mattes, 2023, Respiratory Research.

Influence of whey protein hydrolysis in combination with dextran glycation on immunoglobulin E binding capacity with blood sera obtained from patients with a cow milk protein allergy.

J. Gern, J. Lucey, Lei Xu, 2019, Journal of dairy science.

Challenges and Opportunities in Asthma Prevention and Treatment.

I. Pavord, J. Gern, 2023, The journal of allergy and clinical immunology. In practice.

A motif in the 5'untranslated region of messenger RNAs regulates protein synthesis in a S6 kinase-dependent manner.

N. Jarjour, J. Gern, S. Esnault, 2023, Advances in biological regulation.

Characterization of the Relationship Between Prenatal Farm Exposures and Allergen Sensitization in the First Year of Life

J. Gern, C. Seroogy, Zhumin Zhang, 2021 .

Distinct innate immune cell maturation during the first year of life is associated with farm exposure: 905

Kathrine L. Barnes, Casper G Bendixsen, I. Ong, 2019, Journal of Allergy and Clinical Immunology.

Distinct patterns of bacterial vertical transmission from the maternal vaginal tract to infant gut microbiota: 907

Kathrine L. Barnes, Casper G Bendixsen, J. Gern, 2019, Journal of Allergy and Clinical Immunology.

Evaluation of Indoor Microbiota in Wisconsin Farm Vs. Non-farm Homes Using Electrostatic Dust Collectors

Casper G Bendixsen, R. Vrtis, J. Gern, 2017 .

Comparison of risk factors for viral and nonviral asthma exacerbations

R. Gangnon, J. Gern, R. Lemanske, 2015, Journal of Allergy and Clinical Immunology.

Attenuated P2X7 pore function as a risk factor for virus-induced loss of asthma control.

W. Busse, K. Hogan, R. Sorkness, 2009, American journal of respiratory and critical care medicine.

Risk Factors for the Persistent Expression of Atopic Dermatitis in a High-Risk Birth Cohort

R. Gangnon, J. Gern, R. Lemanske, 2006 .

Atypical presentation of IL-12 receptor beta1 deficiency with pneumococcal sepsis and disseminated nontuberculous mycobacterial infection in a 19-month-old girl born to nonconsanguineous US residents.

S. Holland, T. Torgerson, S. Rosenzweig, 2010, The Journal of allergy and clinical immunology.

A Functional Genomics Pipeline to Identify High-Value Asthma and Allergy CpGs in the Human Methylome.

Matthew C. Altman, K. Barnes, L. Bacharier, 2023, The Journal of allergy and clinical immunology.

Pulmonary function and bronchial reactivity 4 years after the first virus‐induced wheezing

C. Camargo, T. Vahlberg, T. Jartti, 2018, Allergy.

Rhinoviruses

J. Gern, I. Mackay, K. Arden, 2015, Methods in Molecular Biology.

Global DNA methylation changes spanning puberty are near predicted estrogen-responsive genes and enriched for genes involved in endocrine and immune processes

J. Gern, R. Lemanske, D. Jackson, 2018, Clinical Epigenetics.

Early identification of atopy in the prediction of persistent asthma in children

A. Boner, A. Custovic, U. Wahn, 2008, The Lancet.

Genetic associations with viral respiratory illnesses and asthma control in children

D. Nicolae, T. Ahluwalia, K. Bønnelykke, 2016, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function.

Ying Sun, K. Deichmann, D. Nicolae, 2008, The New England journal of medicine.

Randomized trial of omalizumab (anti-IgE) for asthma in inner-city children.

P. Gergen, W. Busse, A. Togias, 2011, The New England journal of medicine.

Relationships among environmental exposures, cord blood cytokine responses, allergy, and wheeze at 1 year of age in an inner-city birth cohort (Urban Environment and Childhood Asthma study).

P. Gergen, J. Gern, D. Gold, 2011, The Journal of allergy and clinical immunology.

Apr 27, 2021 FUT2–ABO epistasis increases the risk of early childhood asthma and Streptococcus

T. Werge, N. Grarup, T. Ahluwalia, 2020 .

Efficacy of inhaled salbutamol with and without prednisolone for first acute rhinovirus‐induced wheezing episode

T. Vahlberg, T. Jartti, J. Gern, 2021, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

International consensus on (ICON) pediatric asthma

H. Zar, G. Wennergren, T. Casale, 2012, Allergy.

Birth cohorts in asthma and allergic diseases: report of a NIAID/NHLBI/MeDALL joint workshop.

Rosalind J Wright, P. Gergen, M. Cabana, 2014, The Journal of allergy and clinical immunology.

Attenuation of Allergic Contact Dermatitis Through the Endocannabinoid System

J. Gern, 2008, Pediatrics.

Rhinoviruses A and C elicit long‐lasting antibody responses with limited cross‐neutralization

P. Gergen, W. Busse, R. Gangnon, 2023, Journal of medical virology.

Human rhinovirus species and season of infection determine illness severity.

Wai-ming Lee, R. Gangnon, J. Gern, 2012, American journal of respiratory and critical care medicine.

Clinical and molecular features of human rhinovirus C.

J. Gern, Y. Bochkov, 2012, Microbes and infection.

Competition among Nasal Bacteria Suggests a Role for Siderophore-Mediated Interactions in Shaping the Human Nasal Microbiota

J. Gern, M. Chevrette, C. Currie, 2018, Applied and Environmental Microbiology.

Early life origins of asthma.

J. Gern, R. Lemanske, William W. Busse, 1999, The Journal of clinical investigation.

The Journal of Allergy and Clinical Immunology: In Practice 2017 Year in Review.

M. Schatz, J. Gern, S. Sicherer, 2018, The journal of allergy and clinical immunology. In practice.

Pyogenic Bacterial Infections in Humans With MyD88 Deficiency

J. Gern, 2009, Pediatrics.

Screen Time Engagement Is Increased in Urban Children With Asthma

P. Gergen, G. O'Connor, L. Bacharier, 2017, Clinical pediatrics.

Improved Molecular Typing Assay for Rhinovirus Species A, B, and C

J. Gern, M. Evans, Y. Bochkov, 2014, Journal of Clinical Microbiology.

The SunBEAm birth cohort: Protocol design

V. Winn, J. Gern, W. Shreffler, 2023, Journal of Allergy and Clinical Immunology: Global.

Recommendations for asthma monitoring in children: A PeARL document endorsed by APAPARI, EAACI, INTERASMA, REG, and WAO

R. Pawankar, O. Yusuf, I. Agache, 2024, Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology.

A polyvalent inactivated rhinovirus vaccine is broadly immunogenic in rhesus macaques

J. Gern, Xiaoyan Lu, K. Roy, 2016, Nature Communications.