J. Pintar

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IGF‐II Promotes Stemness of Neural Restricted Precursors

S. Levison, T. Wood, A. Ziegler, 2012, Stem cells.

NOP receptor antagonists decrease alcohol drinking in the dark in C57BL/6J mice.

J. Pintar, R. Ciccocioppo, Gloria Brunori, 2019, Alcoholism, clinical and experimental research.

A Novel Nociceptin Receptor Antagonist LY2940094 Inhibits Excessive Feeding Behavior in Rodents: A Possible Mechanism for the Treatment of Binge Eating Disorder

J. Pintar, M. Ansonoff, J. Witkin, 2016, The Journal of Pharmacology and Experimental Therapeutics.

Characterization and localization of proopiomelanocortin messenger RNA in the adult rat testis.

D. Krieger, S. Durgerian, J. Pintar, 1984, Science.

Oxidative Metabolism as a Modulator of Kratom's Biological Actions.

Samuel T. Slocum, G. Pasternak, J. Pintar, 2021, Journal of medicinal chemistry.

Kappa2 opioid receptor subtype binding requires the presence of the DOR-1 gene.

J. Pintar, M. Ansonoff, Ting Wen, 2010, Frontiers in bioscience.

Mediation of buprenorphine analgesia by a combination of traditional and truncated mu opioid receptor splice variants

G. Pasternak, J. Pintar, M. Ansonoff, 2016, Synapse.

Induction of the TRPM-2 gene in cells undergoing programmed death

J. Pintar, R. Buttyan, P. Ng, 1989 .

Potentiation of Opioid Analgesia in Dopamine2Receptor Knock-Out Mice: Evidence for a Tonically Active Anti-Opioid System

G. Pasternak, J. Pintar, M. King, 2001, The Journal of Neuroscience.

Lack of genotype effect on D1, D2 receptors and dopamine transporter binding in triple MOP‐, DOP‐, and KOP‐opioid receptor knockout mice of three different genetic backgrounds

B. Kieffer, J. Pintar, Ji-Hoon Yoo, 2010, Synapse.

Opioids and opioid receptors orchestrate wound repair.

J. Pintar, Yunfang Li, M. Ansonoff, 2017, Translational research : the journal of laboratory and clinical medicine.

Immunocytochemical demonstration of monoamine oxidase B in brain astrocytes and serotonergic neurons.

X. Breakefield, P. Levitt, J. Pintar, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Heroin-induced locomotion and mesolimbic dopamine release is unchanged in mice lacking the ORL.1 receptor gene

N. Maidment, Zhenping Chen, J. Pintar, 2002, Brain Research.

PAPA-1 Is a nuclear binding partner of IGFBP-2 and modulates its growth-promoting actions.

H. Ariga, P. Cohen, J. Pintar, 2009, Molecular endocrinology.

Neuropeptidomic analysis establishes a major role for prohormone convertase‐2 in neuropeptide biosynthesis

D. Steiner, J. Pintar, L. Fricker, 2010, Journal of neurochemistry.

ProSAAS‐derived peptides are regulated by cocaine and are required for sensitization to the locomotor effects of cocaine

R. Rodriguiz, W. Wetsel, J. Pintar, 2017, Journal of neurochemistry.

Insulin-like growth factor (IGF) binding protein-4 is both a positive and negative regulator of IGF activity in vivo.

C. Conover, J. Pintar, A. Schuller, 2008, Molecular endocrinology.

Generation of Antisera to Mouse Insulin-Like Growth Factor Binding Proteins (IGFBP)-1 to -6: Comparison of IGFBP Protein and Messenger Ribonucleic Acid Localization in the Mouse Embryo1.

E. Zwarthoff, N. Dits, J. Pintar, 1999, Endocrinology.

Generation of antisera to mouse insulin-like growth factor binding proteins (IGFBP)-1 to -6: comparison of IGFBP protein and messenger ribonucleic acid localization in the mouse embryo.

E. Zwarthoff, N. Dits, J. Pintar, 1999, Endocrinology.

Insulin-like growth factor binding protein gene expression in the pregnant rat uterus and placenta.

J. Pintar, J. Cerro, 1997, Developmental biology.

The embryonic pattern of rat insulin-like growth factor-I gene expression suggests a role in induction and early growth of the liver.

J. Pintar, R. Streck, 1992, Endocrinology.

Insulin-like growth factor I and II and insulin-like growth factor binding protein-2 RNAs are expressed in adjacent tissues within rat embryonic and fetal limbs.

T. Wood, J. Pintar, R. Streck, 1992, Developmental biology.

Expression of IGF-II, the IGF-II/mannose-6-phosphate receptor and IGFBP-2 during rat embryogenesis.

T. Wood, J. Pintar, L. Rogler, 1991, Advances in experimental medicine and biology.

Pattern of the insulin-like growth factor II gene expression during early mouse embryogenesis.

J. Pintar, A. Efstratiadis, J. E. Lee, 1990, Development.

Pattern of the insulin-like growth factor II gene expression during rat embryogenesis.

J. Pintar, A. Efstratiadis, F. Stylianopoulou, 1988, Development.

Novel Class of Psychedelic Iboga Alkaloids Disrupts Opioid Addiction States

V. Katritch, J. Javitch, J. Pintar, 2021, bioRxiv.

Gene discovery by microarray: identification of novel genes induced during growth factor-mediated muscle cell survival and differentiation.

J. Pintar, P. Rotwein, D. Kuninger, 2004, Genomics.

Enhancement of mammary tumour growth by IGFBP-3 involves impaired T cell accumulation.

R. Baxter, J. Pintar, L. Sedger, 2018, Endocrine-related cancer.

The developmental expression in rat of proteases furin, PC1, PC2, and carboxypeptidase E: implications for early maturation of proteolytic processing capacity

N. Seidah, J. Pintar, R. Scott, 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Brain region-specific N-glycosylation and lipid rafts association of the rat mu opioid receptor.

W. Xu, J. Pintar, P. Chong, 2008, Biochemical and biophysical research communications.

Contrasting effects of IGF binding protein‐3 expression in mammary tumor cells and the tumor microenvironment

R. Baxter, J. Pintar, S. Twigg, 2019, Experimental cell research.

Induction of the TRPM-2 gene in cells undergoing programmed death

C. Olsson, Chawnshang Chang, J. Pintar, 1989, Molecular and cellular biology.

IGFBP3 suppresses retinopathy through suppression of oxygen-induced vessel loss and promotion of vascular regrowth

Lois E. H. Smith, T. Ludwig, J. Pintar, 2007, Proceedings of the National Academy of Sciences.

IGF binding protein-4 is required for the growth effects of glucagon-like peptide-2 in murine intestine.

J. Pintar, P. Brubaker, Kaori Austin, 2015, Endocrinology.

Specificity of antisera prepared against pure bovine MAO-B

X. Breakefield, Pat Levitt, J. Pintar, 1983, Brain Research.

Autocrine expression and ontogenetic functions of the PACAP ligand/receptor system during sympathetic development.

J. Pintar, X. Zhou, W. Friedman, 2000, Developmental biology.

Altered Processing of Pro-Orphanin FQ/Nociceptin and Pro-Opiomelanocortin-Derived Peptides in the Brains of Mice Expressing Defective Prohormone Convertase 2

R. G. Allen, D. Grandy, J. Pintar, 2001, The Journal of Neuroscience.

Ontogeny of Prohormone Convertases in Rat Prenatal Development a

J. Pintar, M. Zheng, JOHN E. PINTAR, 1997, Annals of the New York Academy of Sciences.

Embryonic and uterine expression patterns of peptidylglycine alpha-amidating monooxygenase transcripts suggest a widespread role for amidated peptides in development.

J. Pintar, B. Eipper, M. Zheng, 1997, Developmental biology.

Analysis of proopiomelanocortin gene expression during prenatal development of the rat pituitary gland.

J. Roberts, J. Pintar, D. I. Lugo, 1989, Molecular endocrinology.

Biosynthesis and processing of pro-opiomelanocortin-derived peptides during fetal pituitary development.

R. G. Allen, J. Pintar, J. Stack, 1984, Developmental biology.

Proopiomelanocortin Gene Expression, Prohormone Processing, and Secretion during Rat Pituitary Development a

J. Pintar, D. I. Lugo, DELIA I. LUGO, 1987, Annals of the New York Academy of Sciences.

Diminished growth and enhanced glucose metabolism in triple knockout mice containing mutations of insulin-like growth factor binding protein-3, -4, and -5.

T. Ludwig, J. Pintar, J. Frystyk, 2006, Molecular endocrinology.

The expression pattern of an insulin-like growth factor (IGF)-binding protein gene is distinct from IGF-II in the midgestational rat embryo.

T. Wood, J. Pintar, M. Rechler, 1990, Molecular endocrinology.

Gene for monoamine oxidase type A assigned to the human X chromosome

U. Francke, X. Breakefield, J. Pintar, 1981, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Exogenous GLP-2 and IGF-I induce a differential intestinal response in IGF binding protein-3 and -5 double knockout mice.

J. Pintar, D. Ney, A. Brinkman, 2012, American journal of physiology. Gastrointestinal and liver physiology.

Intestinotrophic effects of exogenous IGF-I are not diminished in IGF binding protein-5 knockout mice.

J. Pintar, D. Ney, M. Clayton, 2007, American journal of physiology. Regulatory, integrative and comparative physiology.

Contribution of the Opioid System to the Antidepressant Effects of Fluoxetine

H. Akil, R. Hen, J. Pintar, 2022, Biological Psychiatry.

Mexneurin is a novel precursor of peptides in the central nervous system of rodents

J. Pintar, G. Gamba, C. Allen, 2017, FEBS letters.

Mice lacking proSAAS display alterations in emotion, consummatory behavior and circadian entrainment

Dipendra K. Aryal, R. Rodriguiz, W. Wetsel, 2022, Genes, brain, and behavior.

Tissue-specific and developmentally regulated transcription of the insulin-like growth factor 2 gene.

A. Ullrich, W. Cavenee, A. W. Tam, 1987, DNA.

Serum complexes of insulin‐like growth factor‐1 modulate skeletal integrity and carbohydrate metabolism

M. Bouxsein, O. Gavrilova, P. Cohen, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Expression of functional μ-opioid receptors during T cell development

J. Pintar, T. Rogers, I. Szabo, 2001, Journal of Neuroimmunology.

Morphine induces mesangial cell proliferation and glomerulopathy via kappa-opioid receptors.

J. Pintar, R. Hebbel, M. Ansonoff, 2008, American journal of physiology. Renal physiology.

The histochemical specificity ofStreptomyces hyaluronidase and chondroitinase ABC

J. Pintar, M. Derby, 1978, The Histochemical Journal.

FBNTI, a DOR-selective antagonist that allosterically activates MOR within a MOR-DOR heteromer.

J. Pintar, M. Ansonoff, P. Portoghese, 2020, Biochemistry.

Truncated G protein-coupled mu opioid receptor MOR-1 splice variants are targets for highly potent opioid analgesics lacking side effects

G. Pasternak, J. Pintar, M. Ansonoff, 2011, Proceedings of the National Academy of Sciences.

Mice lacking (cid:1) -opioid receptors resist the development of diet-induced obesity

M. Tschöp, J. Pintar, M. Statnick, 2012 .

Comparison of Receptor Mechanisms and Efficacy Requirements for δ-Agonist-Induced Convulsive Activity and Antinociception in Mice

J. Pintar, K. Rice, J. Woods, 2002, Journal of Pharmacology and Experimental Therapeutics.

Neuroendocrine protein 7B2 is essential for proteolytic conversion and activation of proprotein convertase 2 in vivo.

J. Pintar, D. Savaria, R. Day, 1998, DNA and cell biology.

Site selective C–H functionalization of Mitragyna alkaloids reveals a molecular switch for tuning opioid receptor signaling efficacy

J. Javitch, J. Pintar, M. Ansonoff, 2020, Nature communications.

Synthesis and Pharmacology of a Novel μ-δ Opioid Receptor Heteromer-Selective Agonist Based on the Carfentanyl Template.

J. Pintar, M. Ansonoff, L. Devi, 2020, Journal of medicinal chemistry.

7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects

G. Pasternak, J. Javitch, J. Pintar, 2019, ACS central science.

Differential Activation and Trafficking of μ-Opioid Receptors in Brain Slices

M. Low, M. von Zastrow, John T. Williams, 2008, Molecular Pharmacology.

Pharmacologic Characterization in the Rat of a Potent Analgesic Lacking Respiratory Depression, IBNtxA

G. Pasternak, J. Pintar, M. Ansonoff, 2014, The Journal of Pharmacology and Experimental Therapeutics.

The MOR-1 opioid receptor regulates glucose homeostasis by modulating insulin secretion.

J. Pintar, Ting Wen, B. Peng, 2009, Molecular endocrinology.

IGFBP-3 and TNF-α regulate retinal endothelial cell apoptosis.

J. Pintar, T. Kern, Matthew J. Miller, 2013, Investigative ophthalmology & visual science.

Consequences of opioid receptor mutation on actions of univalent and bivalent kappa and delta ligands

J. Pintar, M. Ansonoff, P. Portoghese, 2010, Psychopharmacology.

The δ-opioid receptor participates in T-cell development by promoting negative selection

J. Pintar, T. Rogers, J. Nitsche, 2004, Journal of Neuroimmunology.

Genetic approaches to the function of insulin-like growth factor-binding proteins during rodent development.

T. Wood, J. Pintar, J. Cerro, 1996, Hormone research.

Mu opioid receptors on hippocampal GABAergic interneurons are critical for the antidepressant effects of tianeptine

R. Hen, J. Javitch, Alexander Z. Harris, 2021, Neuropsychopharmacology.

Targeted disruption of IGFBP-2 gene.

T. Wood, J. Pintar, L. Rogler, 1993, Growth regulation.

Autoradiography of opioid and ORL1 ligands in opioid receptor triple knockout mice

J. Pintar, T. Czyzyk, I. Kitchen, 2002, The European journal of neuroscience.

Morphine-6-glucuronide induces hyperalgesic responses to experimental heat pain in mice and healthy volunteers

J. Pintar, Caroline A. Arout, E. Dorp, 2009 .

Tetrapeptide Endomorphin Analogs Require Both Full Length and Truncated Splice Variants of the Mu Opioid Receptor Gene Oprm1 for Analgesia.

G. Pasternak, J. Pintar, Ying-Xian Pan, 2016, ACS chemical neuroscience.

Developmental regulation of proopiomelanocortin gene expression in the fetal and neonatal rat pituitary.

J. Pintar, R. Scott, 1993, Molecular endocrinology.

Circadian Integration of Glutamatergic Signals by Little SAAS in Novel Suprachiasmatic Circuits

M. Gillette, J. Sweedler, J. Pintar, 2010, PloS one.

Morphine tolerance and dependence in nociceptin/orphanin fq transgenic knock-out mice

J. Pintar, J. Mogil, B. Kest, 2001, Neuroscience.

Developmental changes in levels of proopiomelanocortin intron A-containing heterogeneous nuclear RNA and mature messenger RNA in the anterior and neurointermediate lobes of the rat pituitary.

J. Roberts, J. Pintar, R. Scott, 1990, Molecular endocrinology.

Quantitative autoradiographic mapping of the ORL1, μ-, δ- and κ-receptors in the brains of knockout mice lacking the ORL1 receptor gene

J. Pintar, I. Kitchen, R. Hill, 2001, Brain Research.

Biochemical and genetic analysis of MAO A and B

R. Cawthon, J. Pintar, C. Castiglione, 1981 .

Selective reward deficit in mice lacking beta-endorphin and enkephalin.

M. Low, J. Pintar, M. Hayward, 2002, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Localization of opioid receptor antagonist [3H]-LY255582 binding sites in mouse brain: Comparison with the distribution of mu, delta and kappa binding sites

J. Pintar, T. Suter, M. Statnick, 2005, Neuropeptides.

Monoamine oxidase (MAO) activity as a determinant in human neurophysiology

X. Breakefield, J. Pintar, 1982, Behavior genetics.

Analysis of developmentally homogeneous neural crest cell populations in vitro. IV. Cell proliferation and synthesis of glycosaminoglycans.

J. Pintar, B. Glimelius, 1981, Cell differentiation.

Antinociceptive and Hypothermic Effects of Salvinorin A Are Abolished in a Novel Strain of κ-Opioid Receptor-1 Knockout Mice

B. Roth, J. Pintar, M. Ansonoff, 2006, Journal of Pharmacology and Experimental Therapeutics.

Expression of opioid receptors and ligands in pregnant mouse uterus and placenta.

J. Pintar, Y. Zhu, 1998, Biology of reproduction.

Differences in the Structure of A and B Forms of Human Monoamine Oxidase

R. Cawthon, X. Breakefield, J. Pintar, 1981, Journal of neurochemistry.

Ontogeny of Mammalian Opioid Systems

J. Pintar, R. Scott, 1993 .

Kappa opioid receptor contributes to EGF-stimulated neurite extension in development

H. Loh, J. Pintar, Li-Na Wei, 2010, Proceedings of the National Academy of Sciences.

Differences in monoamine oxidase activity between cultured noradrenergic and cholinergic sympathetic neurons.

X. Breakefield, J. Pintar, P. Patterson, 1987, Developmental biology.

Specific cellular expression of monoamine oxidase B during early stages of quail embryogenesis.

P. Levitt, J. Pintar, G. D. Maxwell, 1985, Developmental biology.

Characterization of monoamine oxidase activity during early stages of quail embryogenesis

X. Breakefield, J. Pintar, G. D. Maxwell, 1983, International Journal of Developmental Neuroscience.

Differential sensitivities of mouse strains to morphine and [Dmt1]DALDA analgesia

G. Pasternak, J. Pintar, M. Ansonoff, 2003, Brain Research.

Genetic Studies of Opioid System Function in Mice

J. Pintar, M. Ansonoff, Ting Wen, 2011 .

Developmental Expression of the μ, κ, and δ Opioid Receptor mRNAs in Mouse

J. Pintar, Yanxin Zhu, M. Hsu, 1998, The Journal of Neuroscience.

Regulation of Opioid Receptors by Their Endogenous Opioid Peptides

S. Gullapalli, J. Pintar, L. Devi, 2021, Cellular and molecular neurobiology.

Transiently catecholaminergic (TC) cells in the bowel of the fetal rat: precursors of noncatecholaminergic enteric neurons.

J. Pintar, M. Gershon, G. Baetge, 1990, Developmental biology.

Reversal of physiological deficits caused by diminished levels of peptidylglycine alpha-amidating monooxygenase by dietary copper.

R. Mains, J. Pintar, B. Eipper, 2009, Endocrinology.

A role for heterodimerization of μ and δ opiate receptors in enhancing morphine analgesia

Lakshmi A. Devi, Hazel H. Szeto, J. Pintar, 2004 .

Retention of Supraspinal Delta-like Analgesia and Loss of Morphine Tolerance in δ Opioid Receptor Knockout Mice

Joshua F. Nitsche, G. Pasternak, J. Pintar, 1999, Neuron.

[3] Analysis of ontogeny of processing enzyme gene expression and regulation

J. Pintar, M. Zheng, 1995 .

Molecular studies of pituitary gland differentiation.

J. Pintar, 1984, Advances in experimental medicine and biology.

Distribution and synthesis of glycosaminoglycans during quail neural crest morphogenesis.

J. Pintar, 1978, Developmental biology.

Operant self-administration of ethanol in C57BL/6 mice lacking β-endorphin and enkephalin

M. Low, J. Pintar, Stephen T. Hansen, 2004, Pharmacology Biochemistry and Behavior.

CURRENT GENETIC APPROACHES TO THE MAMMALIAN NERVOUS SYSTEM

X. Breakefield, J. Pintar, M. B. Rosenberg, 1982 .

Neuropathic Pain Activates the Endogenous κ Opioid System in Mouse Spinal Cord and Induces Opioid Receptor Tolerance

M. Caron, R. Lefkowitz, J. Pintar, 2004, The Journal of Neuroscience.

Genetic Dissociation of Opiate Tolerance and Physical Dependence in δ-Opioid Receptor-1 and Preproenkephalin Knock-Out Mice

G. Pasternak, J. Pintar, A. Schuller, 2002, The Journal of Neuroscience.

Essential role of mu opioid receptor in the regulation of delta opioid receptor–mediated antihyperalgesia

J. Pintar, L. Gendron, C. Chavkin, 2007, Neuroscience.

A comprehensive study on the putative δ-opioid receptor (sub)types using the highly selective δ-antagonist, Tyr-Tic-(2S,3R)-β-MePhe-Phe-OH

K. Gulya, J. Pintar, L. Bakota, 2011, Neurochemistry International.

Essential role of MOR in the regulation of DOR-mediated antihyperalgesia

J. Pintar, L. Gendron, C. Chavkin, 2008 .

Improgan, a cimetidine analog, induces morphine-like antinociception in opioid receptor-knockout mice

R. Leurs, J. Pintar, H. Timmerman, 2000, Brain Research.

Exploring Pharmacological Functions of Alternatively Spliced Variants of the Mu Opioid Receptor Gene, Oprm1, via Gene-Targeted Animal Models

L. Cartegni, J. Pintar, Ying-Xian Pan, 2022, International journal of molecular sciences.

Targeted Deletion of the Vgf Gene Indicates that the Encoded Secretory Peptide Precursor Plays a Novel Role in the Regulation of Energy Balance

J. Takahashi, C. Priest, C. Boozer, 1999, Neuron.

Region-specific expression of mouse homeobox genes in the embryonic mesoderm and central nervous system.

J. Pintar, M. C. Nguyen-Huu, K. Slawin, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Identification of mouse CPX-1, a novel member of the metallocarboxypeptidase gene family with highest similarity to CPX-2.

J. Pintar, L. Fricker, X. Xin, 1999, DNA and cell biology.

Editorial: Current Perspectives on Insulin-Like Growth Factor Binding Protein (IGFBP) Research

A. Hoeflich, B. Forbes, J. Pintar, 2018, Front. Endocrinol..

Selective alterations in organ sizes in mice with a targeted disruption of the insulin-like growth factor binding protein-2 gene.

T. Wood, J. Pintar, L. Rogler, 2000, Molecular endocrinology.

Expression of IGF system genes during T-antigen driven pituitary tumorigenesis.

M. Low, J. Pintar, A. Schuller, 1999, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.

Developmental expression of VGF mRNA in the prenatal and postnatal rat

J. Pintar, S. Salton, S. Snyder, 1998, The Journal of comparative neurology.

The role of prohormone convertase‐2 in hypothalamic neuropeptide processing: a quantitative neuropeptidomic study

Bonnie Peng, D. Steiner, J. Pintar, 2006, Journal of neurochemistry.

Loss of the mu opioid receptor on different genetic backgrounds leads to increased bromodeoxyuridine labeling in the dentate gyrus only after repeated injection

J. Pintar, M. Ansonoff, M. Ansonoff, 2012, Neuroscience.

Genetic and pharmacological manipulation of μ opioid receptors in mice reveals a differential effect on behavioral sensitization to cocaine

J. Pintar, E. Unterwald, M. Hummel, 2004, Neuroscience.

Tissue-specific expression of the insulin-like growth factor binding protein (IGFBP) mRNAs in mouse and rat development

T. Wood, J. Pintar, J. Cerro, 1993, Regulatory Peptides.

Cellular actions of opioids on periaqueductal grey neurons from C57B16/J mice and mutant mice lacking MOR‐1

E. E. Bagley, J. Pintar, S. Hack, 2003, British journal of pharmacology.

Demonstration of Lysosomal Localization for the Mammalian Ependymin-related Protein Using Classical Approaches Combined with a Novel Density Shift Method*

J. Pintar, M. Jadot, D. Sleat, 2006, Journal of Biological Chemistry.

Distinct expression patterns of insulin-like growth factor binding proteins 2 and 5 during fetal and postnatal development.

T. Wood, J. Pintar, P. Rotwein, 1994, Endocrinology.

Genetic ablation of IGFBP-2 suggests functional redundancy in the IGFBP family.

J. Pintar, A. Schuller, J. Cerro, 1995, Progress in growth factor research.

Mortality in 7B2 null mice can be rescued by adrenalectomy: Involvement of dopamine in ACTH hypersecretion

D. Steiner, I. Lindberg, P. Zhu, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Expression of the IGFBP-2 gene in post-implantation rat embryos.

T. Wood, J. Pintar, R. Streck, 1992, Development.

Deletion of peptide amidation enzymatic activity leads to edema and embryonic lethality in the mouse.

R. Mains, J. Pintar, B. Eipper, 2005, Developmental biology.

Expression of VGF mRNA in developing neuroendocrine and endocrine tissues.

J. Pintar, S. Salton, B. Peng, 2003, The Journal of endocrinology.

Prolonged Kappa Opioid Receptor Phosphorylation Mediated by G-protein Receptor Kinase Underlies Sustained Analgesic Tolerance*

M. Caron, R. Lefkowitz, J. Pintar, 2004, Journal of Biological Chemistry.

Defective Prodynorphin Processing in Mice Lacking Prohormone Convertase PC2

A. Polonskaia, D. Steiner, J. Pintar, 2000, Journal of neurochemistry.

κ‐Opioid receptors control the metabolic response to a high‐energy diet in mice

J. Lockwood, M. Tschöp, J. Pintar, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Potentiating effect of morphine on oral Salmonella enterica serovar Typhimurium infection is μ-opioid receptor-dependent.

J. Gaughan, J. Pintar, T. Eisenstein, 2010, Microbial pathogenesis.

Expression of the P450 side-chain cleavage and adrenodoxin genes begins during early stages of adrenal cortex development.

J. Pintar, L. Rogler, 1993, Molecular endocrinology.

Guinea pig pancreatic ganglia: Projections, transmitter content, and the type‐specific localization of monoamine oxidase

J. Pintar, A. Kirchgessner, 1991, The Journal of comparative neurology.

Expression of functional mu-opioid receptors during T cell development.

J. Pintar, T. Rogers, I. Szabo, 2001, Journal of neuroimmunology.

The developmental expression in the rat CNS and peripheral tissues of proteases PC5 and PACE4 mRNAs: comparison with other proprotein processing enzymes.

N. Seidah, J. Pintar, M. Zheng, 1997, Developmental biology.

Potentiation of the D2 mutant motor phenotype in mice lacking dopamine D2 and D3 receptors

J. Brosius, J. Pintar, B. Skryabin, 1999, Neuroscience.

Novel Class of Psychedelic Iboga Alkaloids Disrupts Opioid Use

V. Katritch, J. Javitch, J. Pintar, 2021, bioRxiv.

Type‐specific localization of monoamine oxidase in the enteric nervous system: Relationship to 5‐hydroxytryptamine, neuropeptides, and sympathetic nerves

D. Sherman, J. Pintar, M. Gershon, 1990, The Journal of comparative neurology.

Selective Reward Deficit in Mice Lacking β-Endorphin and Enkephalin

M. Low, J. Pintar, M. Hayward, 2002, The Journal of Neuroscience.

The biology of Nociceptin/Orphanin FQ (N/OFQ) related to obesity, stress, anxiety, mood, and drug dependence.

J. Pintar, M. Ansonoff, J. Witkin, 2014, Pharmacology & therapeutics.

Strain-dependent influences on the hypothalamo-pituitary-adrenal axis profoundly affect the 7B2 and PC2 null phenotypes.

D. Steiner, I. Lindberg, J. Pintar, 2005, Endocrinology.

Opioid Receptor-Induced GTPγ35S Binding during Mouse Development

J. Pintar, J. Nitsche, 2003 .

Retention of heroin and morphine–6β–glucuronide analgesia in a new line of mice lacking exon 1 of MOR–1

G. Pasternak, J. Pintar, Ying-Xian Pan, 1999, Nature Neuroscience.

Delayed mammary gland involution in mice with mutation of the insulin-like growth factor binding protein 5 gene.

Bao Hoang, T. Wood, J. Pintar, 2007, Endocrinology.

Stimulation of beta-endorphin secretion by corticotropin-releasing factor in primary rat Leydig cell cultures.

J. Pintar, B. Schachter, D. I. Lugo, 1989, Endocrinology.

Role of opioid receptor like-1 receptor in modulation of endocrine, immunological, and behavioral responses to the T-cell superantigen staphylococcal enterotoxin A

J. Pintar, M. Ansonoff, A. Kusnecov, 2010, Journal of Neuroimmunology.

Ontogeny of basal and regulated secretion from POMC cells of the developing anterior lobe of the rat pituitary gland.

J. Pintar, D. I. Lugo, 1996, Developmental Biology.

The Behavioral Effects of the Antidepressant Tianeptine Require the Mu-Opioid Receptor

R. Hen, J. Javitch, J. Pintar, 2017, Neuropsychopharmacology.

Preclinical findings predicting efficacy and side‐effect profile of LY2940094, an antagonist of nociceptin receptors

Janice W. Smith, D. McKinzie, J. Pintar, 2016, Pharmacology research & perspectives.

Expression of the gene for the neuronal intermediate filament protein α‐internexin coincides with the onset of neuronal differentiation in the developing rat nervous system

R. Liem, T. Wood, J. Pintar, 1994, The Journal of comparative neurology.

Insulin-like growth factor binding protein-3 links obesity and breast cancer progression

R. Baxter, J. Pintar, T. Chan-Ling, 2016, Oncotarget.

Unresponsiveness of mu‐opioid receptor knockout mice to lipopolysaccharide‐induced fever

J. Pintar, M. Adler, E. B. Geller, 2005, British journal of pharmacology.

Site selective C–H functionalization of Mitragyna alkaloids reveals a molecular switch for tuning opioid receptor signaling efficacy

J. Javitch, J. Pintar, M. Ansonoff, 2021, Nature Communications.

Increased gabaergic input to ventral tegmental area dopaminergic neurons associated with decreased cocaine reinforcement in μ-opioid receptor knockout mice

J. M. Ree, J. Pintar, G. Ramakers, 2005, Neuroscience.

Decreased firing frequency of midbrain dopamine neurons in mice lacking mu opioid receptors

M. Marinelli, J. Pintar, Geert M. J. Ramakers, 2005, The European journal of neuroscience.

μ‐opioid receptor modulation of calcium channel current in periaqueductal grey neurons from C57B16/J mice and mutant mice lacking MOR‐1

J. Pintar, M. Connor, M. Christie, 1999, British journal of pharmacology.

Epidermal stem cells are retained in vivo throughout skin aging

F. Watt, Mei Qin, J. Pintar, 2008, Aging cell.

GPR171 is a hypothalamic G protein-coupled receptor for BigLEN, a neuropeptide involved in feeding

Dipendra K. Aryal, R. Rodriguiz, W. Wetsel, 2013, Proceedings of the National Academy of Sciences.

Mu‐opioid receptor knockout mice show diminished food‐anticipatory activity

R. van den Bos, M. Kas, B. Spruijt, 2004, The European journal of neuroscience.

Role of Insulin-Like Growth Factor-Binding Protein 5 (IGFBP5) in Organismal and Pancreatic β-Cell Growth.

K. Kaestner, M. Birnbaum, J. Pintar, 2009, Endocrine reviews.

Role of Insulin-Like Growth Factor-Binding Protein 5 (IGFBP5) in Organismal and Pancreatic β-Cell Growth.

K. Kaestner, M. Birnbaum, J. Pintar, 2009, Endocrine reviews.

Subcellular Localization of Mannose 6-Phosphate Glycoproteins in Rat Brain*

J. Pintar, R. Wattiaux, M. Jadot, 1999, The Journal of Biological Chemistry.

Endogenous κ-Opioid Receptor Systems Regulate Mesoaccumbal Dopamine Dynamics and Vulnerability to Cocaine

V. Chefer, T. Shippenberg, J. Pintar, 2005, The Journal of Neuroscience.

Strain-specific steroidal control of pituitary function.

I. Lindberg, J. Pintar, R. Day, 2007, The Journal of endocrinology.

Nociceptin/Orphanin FQ (N/OFQ)-Evoked Bradycardia, Hypotension, and Diuresis Are Absent in N/OFQ Peptide (NOP) Receptor Knockout Mice

J. Pintar, M. Ansonoff, D. Kapusta, 2008, Journal of Pharmacology and Experimental Therapeutics.

Quantitative autoradiographic mapping of the ORL1, mu-, delta- and kappa-receptors in the brains of knockout mice lacking the ORL1 receptor gene.

J. Pintar, I. Kitchen, R. Hill, 2001, Brain research.

Nociceptin/orphanin FQ knockout mice display up-regulation of the opioid receptor-like 1 receptor and alterations in opioid receptor expression in the brain

J. Pintar, I. Kitchen, R. Hill, 2003, Neuroscience.

A role for heterodimerization of mu and delta opiate receptors in enhancing morphine analgesia.

Lakshmi A Devi, J. Pintar, H. Szeto, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Female preproenkephalin-knockout mice display altered emotional responses.

D. Pfaff, S. Ogawa, R. Bodnar, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Differential involvement of endogenous opioids in sucrose consumption and food reinforcement

M. Low, J. Pintar, M. Hayward, 2006, Pharmacology Biochemistry and Behavior.

Prior Activation of Kappa Opioid Receptors by U50,488 Mimics Repeated Forced Swim Stress to Potentiate Cocaine Place Preference Conditioning

J. Pintar, Shuang Li, C. Chavkin, 2006, Neuropsychopharmacology.

The PACAP Ligand/Receptor System Regulates Cerebral Cortical Neurogenesis a

J. Pintar, Jiwen Zhang, E. Dicicco-Bloom, 1998, Annals of the New York Academy of Sciences.

Targeted mutagenesis of processing enzymes and regulators: Implications for development and physiology

J. Pintar, T. Czyzyk, Jiwen Zhang, 2003, Journal of neuroscience research.

Mice lacking δ‐opioid receptors resist the development of diet‐induced obesity

M. Tschöp, J. Pintar, M. Statnick, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Morphine Stimulates Wound Healing Via Mu Opioid Receptor and Promotes Wound Closure in Sickle Mice

J. Pintar, R. Hebbel, M. Ansonoff, 2011 .

Regulation of Opioid Receptors by Their Endogenous Opioid Peptides

S. Gullapalli, J. Pintar, L. Devi, 2021, Cellular and Molecular Neurobiology.

The delta-opioid receptor participates in T-cell development by promoting negative selection.

J. Pintar, T. Rogers, J. Nitsche, 2004, Journal of Neuroimmunology.

Developmental Expression of the m , k , and d Opioid Receptor mRNAs in Mouse

J. Pintar, Yanxin Zhu, M. Hsu, 1998 .

THE ACTIONS OF IGFBPS ON GROWTH AND GLUCOSE

J. Pintar, Renping Zhou, 2010 .

Nociception increases during opioid infusion in opioid receptor triple knock-out mice

J. Pintar, B. Kest, G. Klein, 2007, Neuroscience.

Autoradiography in opioid triple knockout mice reveals opioid and opioid receptor like binding of naloxone benzoylhydrazone

J. Pintar, I. Kitchen, R. Hill, 2005, Neuropharmacology.

The MOR-1 opioid receptor regulates glucose homeostasis by modulating insulin secretion.

J. Pintar, Ting Wen, B. Peng, 2009, Molecular endocrinology.

Adaptive changes in the expression of central opioid receptors in mice lacking the dopamine D2 receptor gene

J. Pintar, I. Kitchen, S. Bradshaw, 2008, Neuroscience.

Molecular and Immunocytochemical Studies of Neurofibromas and Related Cell Types a

R. Klein, J. Pintar, J. Fisher, 1986, Annals of the New York Academy of Sciences.

Genetic Analysis of the Endogenous Opioid System

B. Kieffer, J. Pintar, 2004 .

PAM haploinsufficiency does not accelerate the development of diet- and human IAPP-induced diabetes in mice

R. Mains, J. Pintar, Yi-Chun Chen, 2020, Diabetologia.

The propeptide precursor proSAAS is involved in fetal neuropeptide processing and body weight regulation

J. Pintar, L. Devi, L. Fricker, 2010, Journal of neurochemistry.

The morphogenesis of spinal ganglia from neural crest cells.

J. Pintar, J. A. Weston, M. Derby, 1977, Progress in clinical and biological research.

Epidermal stem cells are retained in vivo throughout skin aging

F. Watt, Mei Qin, J. Pintar, 2008, Aging Cell.

Epidermal stem cells are retained in vivo throughout skin aging

F. Watt, Mei Qin, J. Pintar, 2008, Aging cell.

Genetic Dissociation of Opiate Tolerance and Physical Dependence in δ-Opioid Receptor-1 and Preproenkephalin Knock-Out Mice

G. Pasternak, J. Pintar, A. Schuller, 2002, The Journal of Neuroscience.

A Novel Nociceptin Receptor Antagonist LY2940094 Inhibits Excessive Feeding Behavior in Rodents: A Possible Mechanism for the Treatment of Binge Eating Disorder

J. Pintar, M. Ansonoff, J. Witkin, 2016, The Journal of Pharmacology and Experimental Therapeutics.

Characterization of monoamine oxidase activity during early stages of quail embryogenesis

X. Breakefield, J. Pintar, G. D. Maxwell, 1983, International Journal of Developmental Neuroscience.

Serum complexes of insulin‐like growth factor‐1 modulate skeletal integrity and carbohydrate metabolism

M. Bouxsein, O. Gavrilova, P. Cohen, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Endogenous κ-Opioid Receptor Systems Regulate Mesoaccumbal Dopamine Dynamics and Vulnerability to Cocaine

V. Chefer, T. Shippenberg, J. Pintar, 2005, The Journal of Neuroscience.

Embryonic gene expression and pro‐protein processing of proSAAS during rodent development

J. Pintar, L. Devi, Hui Pan, 2005, Journal of neurochemistry.