E. Bacon

发表

An Efficient and Novel Synthesis of Fused Thiazol-2(3H)-ones

Baldev Singh, P. Pennock, G. Y. Lesher, 1993 .

From an Atypical Wake‐promoting Agent to Potent Histamine‐3 Receptor Inverse Agonists

E. Bacon, M. Ator, D. Dunn, 2013, Chemical biology & drug design.

Substituted phenoxypropyl-(R)-2-methylpyrrolidine aminomethyl ketones as histamine-3 receptor inverse agonists.

Allison L. Zulli, E. Bacon, R. Raddatz, 2012, Bioorganic & medicinal chemistry letters.

Nanocrystalline computed tomography contrast agents for blood-pool and liver-spleen imaging.

G. Gazelle, G. Wolf, E. Bacon, 1994, Investigative radiology.

Hepatic imaging with iodinated nanoparticles: a comparison with iohexol in rabbits.

G. Gazelle, E. Halpern, G. Wolf, 1995, Academic radiology.

Nanoparticulate contrast media. Blood-pool and liver-spleen imaging.

T. Desser, D. Rubin, E. Bacon, 1994, Investigative radiology.

Structure-guided identification of novel VEGFR-2 kinase inhibitors via solution phase parallel synthesis.

E. Bacon, B. Ruggeri, J. Mallamo, 2006, Bioorganic & medicinal chemistry letters.

Pharmacokinetics and hepatic disposition of bis[1-(ethoxycarbonyl)propyl]5-acetylamino-2,4,6-triiodoisophthalate in rats and isolated perfused rat livers.

E. Bacon, L. Kinter, G. McIntire, 2000, Drug metabolism and disposition: the biological fate of chemicals.

CEP-26401 (Irdabisant), a Potent and Selective Histamine H3 Receptor Antagonist/Inverse Agonist with Cognition-Enhancing and Wake-Promoting Activities

D. Bozyczko‐Coyne, E. Duzic, M. Williams, 2012, Journal of Pharmacology and Experimental Therapeutics.

Time course of nodal enhancement with CT X-ray nanoparticle contrast agents: effect of particle size and chemical structure.

G. Wolf, E. Bacon, G. McIntire, 2000, Investigative Radiology.

Pulmonary delivery of nanoparticles of insoluble, iodinated CT X-ray contrast agents to lung draining lymph nodes in dogs.

E. Bacon, L. Ketai, K. Nikula, 1998, Journal of pharmaceutical sciences.

Novel and potent adenosine 3',5'-cyclic phosphate phosphodiesterase III inhibitors: thiazolo[4,5-b][1,6]naphthyridin-2-ones.

R. Bentley, M. Connell, P. Pennock, 1995, Journal of medicinal chemistry.

Synthesis of 7-azaindole and 7-azaoxindole derivatives through a palladium-catalyzed cross-coupling reaction

Baldev Singh, G. Y. Lesher, E. Bacon, 1992 .

3-Quinolinecarboxamides. A series of novel orally-active antiherpetic agents.

D. Rosi, E. Bacon, D. Young, 1993, Journal of medicinal chemistry.

Novel cAMP PDE III inhibitors: imidazo[4,5-b]pyridin-2(3H)-ones and thiazolo[4,5-b]pyridin-2(3H)-ones and their analogs.

G. Y. Lesher, E. Bacon, M. Reuman, 1994, Journal of medicinal chemistry.

Regiospecific synthesis of 5-(1H-indol-2-yl)-1- and 2-methyl-6,7-dihydro-2H-indazole isomers

E. Bacon, R. Hudkins, M. Tao, 2007 .

Intramolecular olefinic aldehyde Prins reactions for the construction of five-membered rings

E. Bacon, N. Andersen, J. D. Kelly, 1985 .

1,2,3-Thiadiazole substituted pyrazolones as potent KDR/VEGFR-2 kinase inhibitors.

A. Ghose, E. Bacon, J. Mallamo, 2007, Bioorganic & medicinal chemistry letters.

Synthesis and structure-activity relationships of 6-heterocyclic-substituted purines as inactivation modifiers of cardiac sodium channels.

E. Bacon, W. Volberg, S. Rumney, 1995, Journal of medicinal chemistry.

Intramolecular Olefinic Aldehyde Prins Reactions for the Construction of Five- Membered Rings.

E. Bacon, N. Andersen, J. D. Kelly, 1986 .

Stereochemistry of the type II elimination from 4-tert-butylcyclohexyl phenylacetate

E. Bacon, G. Eadon, P. M. Gold, 1976 .

Wake-promoting agents: search for next generation modafinil: part II.

E. Bacon, M. Ator, Greg A. Hostetler, 2012, Bioorganic & medicinal chemistry letters.

STEREOCHEMISTRY OF THERMAL AND ELECTRON IMPACT INDUCED ELIMINATIONS FROM CYCLIC-ACETATES AND MALONATES

E. Bacon, G. Eadon, P. M. Gold, 1975 .

Identification of pyridazin-3-one derivatives as potent, selective histamine H₃ receptor inverse agonists with robust wake activity.

Allison L. Zulli, E. Bacon, V. R. Marcy, 2011, Bioorganic & medicinal chemistry letters.

Discovery and characterization of 6-{4-[3-(R)-2-methylpyrrolidin-1-yl)propoxy]phenyl}-2H-pyridazin-3-one (CEP-26401, irdabisant): a potent, selective histamine H3 receptor inverse agonist.

M. Williams, E. Bacon, C. Prouty, 2011, Journal of medicinal chemistry.

Synthesis and biological profile of the pan-vascular endothelial growth factor receptor/tyrosine kinase with immunoglobulin and epidermal growth factor-like homology domains 2 (VEGF-R/TIE-2) inhibitor 11-(2-methylpropyl)-12,13-dihydro-2-methyl-8-(pyrimidin-2-ylamino)-4H-indazolo[5,4-a]pyrrolo[3,4-c]

Allison L. Zulli, E. Bacon, B. Ruggeri, 2012, Journal of medicinal chemistry.

Discovery of 7-arylsulfonyl-1,2,3,4, 4a,9a-hexahydro-benzo[4,5]furo[2,3-c]pyridines: identification of a potent and selective 5-HT₆ receptor antagonist showing activity in rat social recognition test.

Karla K Kopec, E. Duzic, E. Bacon, 2012, Bioorganic & medicinal chemistry letters.

6-(4-pyridinyl)-1H-1,2,3-triazolo[4,5-d]-pyrimidin-4(5H)-one: a structurally novel competitive AMPA receptor antagonist.

A. Treasurywala, P. Pennock, E. Bacon, 1995, Journal of medicinal chemistry.

Novel brain penetrant benzofuropiperidine 5-HT₆ receptor antagonists.

Karla K Kopec, E. Duzic, E. Bacon, 2012, Bioorganic & medicinal chemistry letters.

Design and synthesis of dihydroindazolo[5,4-a]pyrrolo[3,4-c]carbazole oximes as potent dual inhibitors of TIE-2 and VEGF-R2 receptor tyrosine kinases.

Allison L. Zulli, E. Bacon, B. Ruggeri, 2008, Bioorganic & medicinal chemistry letters.

Cardiovascular activity of WIN 65579, a novel inhibitor of cyclic GMP phosphodiesterase 5.

E. Bacon, R. Dundore, D. C. Bode, 1998, European journal of pharmacology.

Cyclic GMP potentiation by WIN 58237, a novel cyclic nucleotide phosphodiesterase inhibitor.

G. Y. Lesher, E. Bacon, R. Dundore, 1994, The Journal of pharmacology and experimental therapeutics.

Lymph node extraction of radiopaque nanoparticulates in the rabbit as measured in vivo with CT.

G L Wolf, G. Wolf, E. Bacon, 1999, Academic radiology.

Percutaneous computed tomography lymphography in the rabbit by subcutaneously injected nanoparticulates.

G S Gazelle, G L Wolf, G. Gazelle, 1994, Academic radiology.

CT imaging of intrathoracic lymph nodes in dogs with bronchoscopically administered iodinated nanoparticles.

R. Rosenberg, E. Bacon, L. Ketai, 1999, Academic radiology.

Time-lapse quantitative computed tomography lymphography: assessing lymphatic function in vivo.

G. Gazelle, E. Halpern, G. Wolf, 1994, Academic radiology.

A short and general synthesis of 1,3‐dihydro‐6‐heteroaryl‐5‐perfluoroalkyl‐2H‐imidazo[4,5‐b]pyridin‐2‐ones

Baldev Singh, G. Y. Lesher, E. Bacon, 1993 .

A Short and General Synthesis of 1,3‐Dihydro‐6‐heteroaryl‐5‐ perfluoroalkyl‐2H‐imidazo(4,5‐b)pyridin‐2‐ones.

Baldev Singh, G. Y. Lesher, E. Bacon, 1993 .

Blood pool and liver enhancement in CT with liposomal lodixanol: comparison with lohexol.

D L Rubin, T. Desser, D. Rubin, 1999, Academic radiology.

Stereochemistry of thermal and electron impact induced eliminations from cyclic acetates and malonates

E. Bacon, G. Eadon, P. M. Gold, 1975 .

Interstitial MR and CT lymphography with Gd-DTPA-co-α, ω-diaminoPEG(1450) and Gd-DTPA-co-1,6-diaminohexane polymers: Preliminary experience

T. Desser, D. Rubin, E. Bacon, 1999 .

Nanoparticulate computed tomography contrast agents for blood pool and liver-spleen imaging.

E F Halpern, G S Gazelle, G L Wolf, 1994, Academic radiology.