M. Chu-Moyer

发表

PREPARATION OF THE FOUR REGIOISOMERIC 2-(METHYLTHIO)OXAZOLOPYRIDINES : USEFUL SYNTHONS FOR ELABORATION TO 2-(AMINO SUBSTITUTED)OXAZOLOPYRIDINES

M. Chu-Moyer, R. Berger, 1995 .

An efficient and practical total synthesis of (+)-vincamine from L-aspartic acid

M. Chu-Moyer, P. Gmeiner, H. Rapoport, 1990 .

Application of a Parallel Synthetic Strategy in the Discovery of Biaryl Acyl Sulfonamides as Efficient and Selective NaV1.7 Inhibitors.

Dong Liu, R. Fremeau, H. Bregman, 2016, Journal of medicinal chemistry.

Discovery of highly selective EP4 receptor agonists that stimulate new bone formation and restore bone mass in ovariectomized rats.

V. Paralkar, D. Scott, M. Chu-Moyer, 2006, Bioorganic & medicinal chemistry letters.

1,2,4-Triazolsulfone: A novel isosteric replacement of acylsulfonamides in the context of NaV1.7 inhibition.

Kristin L. Andrews, R. Fremeau, M. Chu-Moyer, 2018, Bioorganic & medicinal chemistry letters.

SAR and species/stereo-selective metabolism of the sorbitol dehydrogenase inhibitor, CP-470,711.

M. Chu-Moyer, P. Oates, J. Coutcher, 2002, Bioorganic & medicinal chemistry letters.

The discovery of benzoxazine sulfonamide inhibitors of NaV1.7: Tools that bridge efficacy and target engagement.

R. Fremeau, H. Bregman, M. Chu-Moyer, 2017, Bioorganic & medicinal chemistry letters.

The total synthesis of dl-indolizomycin

M. Chu-Moyer, Guncheol Kim, S. Danishefsky, 1990 .

A Remarkable Glycosidation Reaction: The Total Synthesis of Calicheamicin .gamma.1I

S. Hitchcock, M. Chu-Moyer, S. Danishefsky, 1995 .

Small atrial natriuretic peptide analogues: design, synthesis, and structural requirements for guanylate cyclase activation.

S. Davidsen, E. Bush, M. Chu-Moyer, 1992, Journal of medicinal chemistry.

Total Synthesis of dl-Indolizomycin.

M. Chu-Moyer, Guncheol Kim, S. Danishefsky, 1990 .

Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency and Pharmacokinetics While Mitigating Metabolic Liabilities.

R. Fremeau, H. Bregman, M. Chu-Moyer, 2017, Journal of Medicinal Chemistry.

The total synthesis of indolizomycin

G. Schulte, M. Chu-Moyer, Guncheol Kim, 1993 .

A remarkable cyclopropanation: the total synthesis of myrocin C

M. Chu-Moyer, S. Danishefsky, 1992 .

Total Synthesis of (.+-.)-Myrocin C

G. Schulte, M. Chu-Moyer, S. Danishefsky, 1994 .

On the mode of action of myrocin C: Evidence for a CC-1065 connection

M. Chu-Moyer, S. Danishefsky, 1993 .

A Remarkable Cyclopropanation: The Total Synthesis of Myrocin C.

M. Chu-Moyer, S. Danishefsky, 1993 .

Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency, Pharmacokinetics, and Metabolic Properties to Obtain Atropisomeric Quinolinone (AM-0466) that Affords Robust in Vivo Activity.

Roman Shimanovich, Angel Guzman-Perez, R. Fremeau, 2017, Journal of medicinal chemistry.

Patent focus on antidiabetic agents: September 1999 - February 2000

M. Chu-Moyer, 2000 .

Orally-effective, long-acting sorbitol dehydrogenase inhibitors: synthesis, structure-activity relationships, and in vivo evaluations of novel heterocycle-substituted piperazino-pyrimidines.

M. Chu-Moyer, R. Berger, P. Oates, 2002, Journal of medicinal chemistry.

A Convergent Total Synthesis of Calicheamicin γI 1.

S. Hitchcock, M. Chu-Moyer, S. Danishefsky, 1994 .

A Convergent Total Synthesis of Calicheamicin γ

S. Hitchcock, M. Chu-Moyer, S. Danishefsky, 1994 .

Expert Opinion on Therapeutic Patents

M. Chu-Moyer, 2000 .

Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency and Pharmacokinetics to Enable in Vivo Target Engagement.

R. Fremeau, H. Bregman, M. Chu-Moyer, 2016, ACS medicinal chemistry letters.