P. Limbach

发表

Mass Spectrometry-Based Methods for Characterization of Hypomodifications in Transfer RNA

Priti Thakur, Manasses Jora, Ruoxia Zhao, 2021, Epitranscriptomics.

Improved RNA modification mapping of cellular non-coding RNAs using C- and U-specific RNases.

Priti Thakur, P. Limbach, B. Addepalli, 2019, The Analyst.

Transcriptome-wide distribution and function of RNA hydroxymethylcytosine

Fei Wang, Matthieu Defrance, Patrick A. Limbach, 2016, Science.

Mycobacterium tuberculosis the 16 S rRNA 530 Loop by GidB in Functional Role of Methylation of G 518 of

G. Piszczek, P. Limbach, B. Addepalli, 2013 .

Functional Role of Methylation of G518 of the 16S rRNA 530 Loop by GidB in Mycobacterium tuberculosis

G. Piszczek, P. Limbach, B. Addepalli, 2013, Antimicrobial Agents and Chemotherapy.

Chimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve Chemosensitivity

P. Limbach, B. Addepalli, S. Zeng, 2015, Drug Metabolism and Disposition.

Bio-MEMS Devices for Proteomics

Justin S. Mecomber, P. Limbach, Wendy D. Dominick, 2006 .

DETECTING LOW-LEVEL SYNTHESIS IMPURITIES IN MODIFIED PHOSPHOROTHIOATE OLIGONUCLEOTIDES USING LIQUID CHROMATOGRAPHY - HIGH RESOLUTION MASS SPECTROMETRY.

P. Limbach, I. Nikčević, T. Wyrzykiewicz, 2011, International journal of mass spectrometry.

Integrating micromachined devices with modern mass spectrometry.

Zhaojing Meng, P. Limbach, Z. Meng, 2002, The Analyst.

Ion trajectories in an electrostatic ion guide for external ion source fourier transform ion cyclotron resonance mass spectrometry

J. Marto, P. Limbach, A. Marshall, 1995, Journal of the American Society for Mass Spectrometry.

Linear excitation and detection in Fourier transform ion cyclotron resonance mass spectrometry

P. Limbach, A. Marshall, P. Grosshans, 1994 .

Fast neutral beam Fourier transform ion cyclotron resonance mass spectrometry for analysis of insulating and conductive materials

P. Limbach, A. Marshall, Hyun Sik Kim, 1993 .

Fast neutral beam ion source coupled to a Fourier transform ion cyclotron resonance mass spectrometer

P. Limbach, A. Marshall, J. Delmore, 1991 .

Use of protein cross-linking and radiolytic footprinting to elucidate PsbP and PsbQ interactions within higher plant Photosystem II

H. Bellamy, M. Brylinski, P. Limbach, 2014, Proceedings of the National Academy of Sciences.

Analysis of Oligonucleotides by Matrix‐Assisted Laser Desorption/Ionization Time‐of‐Flight Mass Spectrometry

P. Limbach, C. Chou, Chau-wen Chou, 2000, Current protocols in nucleic acid chemistry.

MATRIX INFLUENCE ON THE FORMATION OF POSITIVELY CHARGED OLIGONUCLEOTIDES IN MATRIX-ASSISTED LASER DESORPTION/IONIZATION MASS SPECTROMETRY

P. Limbach, C. Chou, P. Williams, 1999 .

Influence of co-matrix proton affinity on oligonucleotide ion stability in matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

P. Limbach, T. Simmons, 1998 .

Surfactant-aided, matrix-assisted laser desorption/ionization mass spectrometry of hydrophobic and hydrophilic peptides.

G. Breaux, P. Limbach, K. Green-Church, 2000, Analytical chemistry.

Selective terminal methylation of a tRNA wobble base

P. Limbach, H. Gamper, R. Takase, 2018, Nucleic acids research.

Fragmentation pathway studies of oligonucleotides in matrix-assisted laser desorption/ionization mass spectrometry by charge tagging and H/D exchange

R. Cole, P. Limbach, C. Chou, 2002, Journal of the American Society for Mass Spectrometry.

Polyamine co-matrices for matrix-assisted laser desorption/ionization mass spectrometry of oligonucleotides.

P. Limbach, V. Vandell, 1999, Rapid communications in mass spectrometry : RCM.

Using Spectral Matching to Interpret LC-MS/MS Data During RNA Modification Mapping.

P. Limbach, Collin Wetzel, M. J. Paulines, 2019, Journal of mass spectrometry : JMS.

Locating chemical modifications in RNA sequences through ribonucleases and LC-MS based analysis.

Priti Thakur, Scott Abernathy, P. Limbach, 2021, Methods in enzymology.

Mass spectrometry sequencing of transfer ribonucleic acids by the comparative analysis of RNA digests (CARD) approach.

P. Limbach, Siwei Li, 2013, The Analyst.

Method for comparative analysis of ribonucleic acids using isotope labeling and mass spectrometry.

P. Limbach, Siwei Li, 2012, Analytical chemistry.

Removal of 3'-phosphate group by bacterial alkaline phosphatase improves oligonucleotide sequence coverage of RNase digestion products analyzed by collision-induced dissociation mass spectrometry.

P. Limbach, B. Addepalli, Kady L. Krivos, 2011, Rapid communications in mass spectrometry : RCM.

Shotgun Sequencing Small Oligonucleotides by Nozzle-Skimmer Dissociation and Electrospray Ionization Mass Spectrometry

P. Limbach, Z. Meng, 2005, European journal of mass spectrometry.

Indirect Mass Spectrometric Methods for Characterizing and Sequencing Oligonucleotides

P. Limbach, 1997 .

Editing and methylation at a single site by functionally interdependent activities

P. Limbach, K. McKenney, M. A. Rubio, 2017, Nature.

The absence of A-to-I editing in the anticodon of plant cytoplasmic tRNAArgACG demands a relaxation of the wobble decoding rules

P. Limbach, K. Gaston, G. Igloi, 2012, RNA biology.

Metabolic De-Isotoping for Improved LC-MS Characterization of Modified RNAs

P. Limbach, Collin Wetzel, Siwei Li, 2014, Journal of The American Society for Mass Spectrometry.

The identification and characterization of non-coding and coding RNAs and their modified nucleosides by mass spectrometry

P. Limbach, K. Gaston, Kirk W. Gaston, 2014, RNA biology.

Multiple endonucleases improve MALDI-MS signature digestion product detection of bacterial transfer RNAs

P. Limbach, Mahmud Hossain, 2009, Analytical and bioanalytical chemistry.

Stable Isotope Labeling for Improved Comparative Analysis of RNA Digests by Mass Spectrometry

P. Limbach, M. J. Paulines, 2017, Journal of The American Society for Mass Spectrometry.

Oligonucleotide analysis by hydrophilic interaction liquid chromatography-mass spectrometry in the absence of ion-pair reagents.

Manasses Jora, P. Limbach, B. Addepalli, 2019, Journal of chromatography. A.

Advances in nucleic acid and protein analyses,manipulation, and sequencing : 26-27 January 2000, San Jose, California

P. Limbach, 2000 .

Gene ssfg_01967 (miaB) for tRNA modification influences morphogenesis and moenomycin biosynthesis in Streptomyces ghanaensis ATCC14672.

Ruoxia Zhao, P. Limbach, S. Walker, 2019, Microbiology.

Survey and Validation of tRNA Modifications and Their Corresponding Genes in Bacillus subtilis sp Subtilis Strain 168

V. de Crécy-Lagard, P. Limbach, V. Marchand, 2020, Biomolecules.

Bacterial biofilms of importance to medicine and bioterrorism: proteomic techniques to identify novel vaccine components and drug targets

D. Hunt, D. Hassett, R. Hancock, 2003, Expert opinion on biological therapy.

Interfaces for capillary LC with ICPMS detection: A comparison of nebulizers/spray chamber configurations

P. Limbach, J. Caruso, K. Lokits, 2009 .

Pytheas: a software package for the automated analysis of RNA sequences and modifications via tandem mass spectrometry

J. Williamson, Scott Abernathy, P. Limbach, 2022, Nature Communications.

On-line sample preconcentration using field-amplified stacking injection in microchip capillary electrophoresis.

W. Heineman, P. Limbach, K. Wehmeyer, 2006, Analytical chemistry.

Electrospray Ionization Mass Spectrometry of Oligonucleotides

P. Limbach, Colette M. Castleberry, L. Rodicio, 2008, Current protocols in nucleic acid chemistry.

Analysis of Oligonucleotides by Electrospray Ionization Mass Spectrometry

P. Limbach, L. M. Polo, L. Polo, 2000, Current protocols in nucleic acid chemistry.

Mass Spectrometry: Nucleic Acids and Nucleotides Studied Using MS

P. Limbach, X. Cao, 2017 .

Mononucleotide gas-phase proton affinities as determined by the kinetic method

P. Limbach, K. Green-church, 2000, Journal of the American Society for Mass Spectrometry.

Induction based fluidics (IBF) for droplet-based mass spectrometric analysis of oligonucleotides.

P. Limbach, Robert L. Ross, A. Sauter, 2015, Journal of mass spectrometry : JMS.

RNase mapping of intact nucleic acids by electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry (ESI-FTICRMS) and 18O labeling

P. Limbach, Z. Meng, 2004 .

Identification of RNA sequence isomer by isotope labeling and LC-MS/MS.

P. Limbach, Siwei Li, 2014, Journal of mass spectrometry : JMS.

Harmonic enhancement of a detected ion cyclotron resonance signal by use of segmented detection electrodes

P. Limbach, A. Marshall, P. Grosshans, 1993 .

An Arabidopsis ATP-Dependent, DEAD-Box RNA Helicase Loses Activity upon IsoAsp Formation but Is Restored by PROTEIN ISOASPARTYL METHYLTRANSFERASE[C][W]

S. Clarke, S. E. Perry, P. Limbach, 2013, Plant Cell.

Analysis of Polymeric Hydrocarbon Materials by Matrix-Assisted Laser Desorption/Ionization (Maldi) Mass Spectrometry

P. Limbach, S. Macha, 2003 .

Combining recombinant ribonuclease U2 and protein phosphatase for RNA modification mapping by liquid chromatography-mass spectrometry.

P. Limbach, Whitney M. Houser, A. Butterer, 2015, Analytical biochemistry.

Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry of polymers

P. Limbach, S. Macha, 2002 .

Separation and identification of phosphorothioate oligonucleotides by HILIC-ESIMS

Patrick A. Limbach, P. Limbach, Colin G. Barry, 2013 .

Selective Detection of Peptide-Oligonucleotide Heteroconjugates Utilizing Capillary HPLC-ICPMS

P. Limbach, J. Caruso, Brittany Catron, 2012, Journal of The American Society for Mass Spectrometry.

Biochemical Applications of Mass Spectrometry

P. Limbach, V. Vandell, 1999 .

Laser Desorption/Ionization (LDI)- and Maldi-Fourier Transform Ion Cyclotron Resonance Mass Spectrometric (FT/ICR/MS) Analysis of Hydrocarbon Samples

P. Limbach, S. Macha, V. Vandell, 2003 .

Chemical Sequencing of Phosphorothioate Oligonucleotides Using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry

P. Limbach, T. McCarley, L. M. Polo, 1997 .

Oxidized Amino Acid Residues in the Vicinity of QA and PheoD1 of the Photosystem II Reaction Center: Putative Generation Sites of Reducing-Side Reactive Oxygen Species

P. Limbach, T. Bricker, L. Sallans, 2013, PloS one.

An electrostatic ion guide for efficient transmission of low energy externally formed ions into a Fourier transform ion cyclotron resonance mass spectrometer

P. Limbach, A. Marshall, Mingda Wang, 1993 .

Estimation of log Pow values for neutral and basic compounds by microchip microemulsion electrokinetic chromatography with indirect fluorimetric detection (μMEEKC-IFD)

W. Heineman, H. Halsall, P. Limbach, 2005 .

Radiolytic Mapping of Solvent-Contact Surfaces in Photosystem II of Higher Plants

H. Bellamy, P. Limbach, J. Goettert, 2013, The Journal of Biological Chemistry.

Observation of the doubly charged, gas-phase fullerene anions C602- and C702-

Alan G. Marshall, Mark T. McDermott, Patrick A. Limbach, 1991 .

Systematic identification of tRNAome and its dynamics in Lactococcus lactis

Z. Ignatova, B. Poolman, Paul Saffert, 2014, Molecular microbiology.

Identification of the enzymes responsible for m2,2G and acp3U formation on cytosolic tRNA from insects and plants

Ruoxia Zhao, P. Limbach, Michael P Guy, 2020, PloS one.

The Effects of Ultraviolet Radiation on Nucleoside Modifications in RNA.

Manasses Jora, P. Limbach, B. Addepalli, 2018, ACS chemical biology.

RNA Cleavage Properties of Nucleobase-Specific RNase MC1 and Cusativin Are Determined by the Dinucleotide-Binding Interactions in the Enzyme-Active Site

Priti Thakur, P. Limbach, B. Addepalli, 2022, International journal of molecular sciences.

A disulfide linkage in a CCCH zinc finger motif of an Arabidopsis CPSF30 ortholog

P. Limbach, B. Addepalli, A. Hunt, 2010, FEBS letters.

Higher-Energy Collisional Dissociation Mass Spectral Networks for the Rapid, Semi-automated Characterization of Known and Unknown Ribonucleoside Modifications.

Manasses Jora, P. Limbach, B. Addepalli, 2022, Analytical chemistry.

Protein Evolution in Yeast Transcription Factor Subnetworks

S. Kasif, R. Roberts, E. Raleigh, 2010 .

Thermus thermophilus L11 Methyltransferase, PrmA, Is Dispensable for Growth and Preferentially Modifies Free Ribosomal Protein L11 Prior to Ribosome Assembly

Jill K Thompson, P. Limbach, D. Cameron, 2004, Journal of bacteriology.

Matrix-assisted laser desorption/ionization mass spectrometry screening for pseudouridine in mixtures of small RNAs by chemical derivatization, RNase digestion and signature products.

P. Limbach, A. Durairaj, 2008, Rapid communications in mass spectrometry : RCM.

Characterization of UVA-Induced Alterations to Transfer RNA Sequences

P. Limbach, B. Addepalli, Congliang Sun, 2020, Biomolecules.

Life without tRNA[superscript Ile]-lysidine synthetase: translation of the isoleucine codon AUA in Bacillus subtilis lacking the canonical tRNA[Ile over 2]

P. Limbach, K. Gaston, U. RajBhandary, 2013 .

Application of nonpolar matrices for the analysis of low molecular weight nonpolar synthetic polymers by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

P. Limbach, S. Macha, P. Savickas, 2000, Journal of the American Society for Mass Spectrometry.

Influence of ionization energy on charge-transfer ionization in matrix-assisted laser desorption/ionization mass spectrometry

P. Limbach, T. McCarley, S. Macha, 1999 .

Electron-transfer ionization in matrix-assisted laser desorption/ionization mass spectrometry

P. Limbach, T. McCarley, R. McCarley, 1998 .

Archaeosine Modification of Archaeal tRNA: Role in Structural Stabilization

V. de Crécy-Lagard, P. Limbach, R. Schmitz, 2020, Journal of bacteriology.

Improving RNA modification mapping sequence coverage by LC-MS through a nonspecific RNase U2-E49A mutant.

P. Limbach, B. Addepalli, Beulah Solivio, 2018, Analytica chimica acta.

A comparative study on methods of optimal sample preparation for the analysis of oligonucleotides by matrix-assisted laser desorption/ionization mass spectrometry.

Tracey A. Simmons, P. Limbach, T. Simmons, 2000, The Analyst.

Dynamic 23S rRNA modification ho5C2501 benefits Escherichia coli under oxidative stress

N. Polacek, P. Limbach, Michel Fasnacht, 2021, Nucleic acids research.

Nano LC-MS using capillary columns enables accurate quantification of modified ribonucleosides at low femtomol levels

Sebastian A. Leidel, S. Leidel, P. Limbach, 2018, RNA.

Diversifying Science, Technology, Engineering, and Mathematics (STEM): An Inquiry into Successful Approaches in Chemistry

M. P. Doyle, I. Warner, L. Marzilli, 2014 .

Overview of Biochemical Applications of Mass Spectrometry

P. Limbach, V. Vandell, 2010 .

Diversity of archaeosine synthesis in crenarchaeota.

V. de Crécy-Lagard, M. Bailly, P. Limbach, 2012, ACS chemical biology.

Mass Spectrometry-Based Quantification of Pseudouridine in RNA

P. Limbach, B. Addepalli, Balasubrahmanyam Addepalli, 2011, Journal of the American Society for Mass Spectrometry.

Halogen-Free Multicomponent Flame Retardant Thermoplastic Styrene–Ethylene–Butylene–Styrene Elastomers Based on Ammonium Polyphosphate–Expandable Graphite Synergy

M. Bastian, P. Limbach, B. Schartel, 2017 .

Bisphenol A facilitates bypass of androgen ablation therapy in prostate cancer

G. Babcock, P. Limbach, K. Knudsen, 2006, Molecular Cancer Therapeutics.

The use of nonpolar matrices for matrix-assisted laser desorption/ionization mass spectrometric analysis of high boiling crude oil fractions.

P. Limbach, C. Robins, 2003, Rapid communications in mass spectrometry : RCM.

Summary: the modified nucleosides of RNA.

P. Limbach, P. Crain, J. McCloskey, 1994, Nucleic acids research.

Investigation of single-site zirconium azaborolinyl complexes by laser desorption ionization time of flight mass spectrometry.

P. Limbach, S. Macha, Barbara M. Tsuie, 2007, Analytica chimica acta.

The autofluorescence of plastic materials and chips measured under laser irradiation.

Aigars Piruska, Irena Nikcevic, W. Heineman, 2005, Lab on a chip.

Electrospray ionization mass spectrometry of metalloporphyrins.

P. Limbach, V. Vandell, 1998, Journal of mass spectrometry : JMS.

Halogen-free fire retardant styrene–ethylene–butylene–styrene-based thermoplastic elastomers using synergistic aluminum diethylphosphinate–based combinations

M. Bastian, P. Limbach, B. Schartel, 2015 .

Differentiating Positional Isomers of Nucleoside Modifications by Higher-Energy Collisional Dissociation Mass Spectrometry (HCD MS)

Manasses Jora, Ruoxia Zhao, P. Limbach, 2018, Journal of The American Society for Mass Spectrometry.

MODOMICS: a database of RNA modification pathways. 2017 update

Tomasz K. Wirecki, J. Bujnicki, P. Limbach, 2017, Nucleic Acids Res..

WITHIN THE IDENTIFICATION OF PUTATIVE Plants : EXPERIMENTAL Surfaces in Photosystem II of Higher Radiolytic Mapping of Solvent-Contact Bioenergetics :

H. Bellamy, P. Limbach, J. Goettert, 2013 .

Identification of oxidized amino acid residues in the vicinity of the Mn(4)CaO(5) cluster of Photosystem II: implications for the identification of oxygen channels within the Photosystem.

P. Limbach, L. Sallans, T. M. Bricker, 2012, Biochemistry.

Extending ribosomal protein identifications to unsequenced bacterial strains using matrix‐assisted laser desorption/ionization mass spectrometry

P. Limbach, Moo-Jin Suh, S. T. Gregory, 2005, Proteomics.

Unlimited-volume electrokinetic stacking injection in sweeping capillary electrophoresis using a cationic surfactant.

W. Heineman, P. Limbach, K. Wehmeyer, 2006, Analytical chemistry.

Indirect mass spectrometric methods for characterizing and sequencing oligonucleotides.

P. Limbach, 1996, Mass spectrometry reviews.

Structural and mechanistic basis for enhanced translational efficiency by 2-thiouridine at the tRNA anticodon wobble position.

J. Perona, R. Kaiser, P. Limbach, 2013, Journal of molecular biology.

Going global: the new era of mapping modifications in RNA

P. Limbach, M. J. Paulines, 2017, Wiley interdisciplinary reviews. RNA.

Functional characterization of the YmcB and YqeV tRNA methylthiotransferases of Bacillus subtilis

S. Kasif, R. Roberts, B. Anton, 2010, Nucleic acids research.

A common tRNA modification at an unusual location: the discovery of wyosine biosynthesis in mitochondria

P. Limbach, M. A. Rubio, J. Alfonzo, 2015, Nucleic acids research.

Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of oligonucleotides.

P. Limbach, Colette M. Castleberry, Chau-wen Chou, 2008, Current protocols in nucleic acid chemistry.

Mass spectrometry of modified RNAs: recent developments.

P. Limbach, Collin Wetzel, 2016, The Analyst.

Plant, Animal, and Fungal Micronutrient Queuosine Is Salvaged by Members of the DUF2419 Protein Family

V. de Crécy-Lagard, F. Forouhar, J. Hunt, 2014, ACS chemical biology.

Instrumental analysis of RNA modifications

Manasses Jora, P. Limbach, C. Tisné, 2021, Critical reviews in biochemistry and molecular biology.

Sequence mapping of transfer RNA chemical modifications by liquid chromatography tandem mass spectrometry.

P. Limbach, Robert L. Ross, Xiaoyu Cao, 2016, Methods.

Solution chemistry effects on the analysis of DNA by matrix-assisted laser desorption/ionization mass spectrometry

Kari B. Green-Church, Patrick A. Limbach, Tracey A. Simmons, 1997, Photonics West - Biomedical Optics.

RNA abasic sites in yeast and human cells

Joshua T. Burdick, Samuel H. Wilson, V. Cheung, 2020, Proceedings of the National Academy of Sciences.

Life without tRNAIle-lysidine synthetase: translation of the isoleucine codon AUA in Bacillus subtilis lacking the canonical tRNA2Ile

P. Limbach, K. Gaston, U. RajBhandary, 2013, Nucleic acids research.

The global identification of tRNA isoacceptors by targeted tandem mass spectrometry.

P. Limbach, Collin Wetzel, 2013, The Analyst.

Global identification of transfer RNAs by liquid chromatography-mass spectrometry (LC-MS).

P. Limbach, Collin Wetzel, 2012, Journal of proteomics.

MODOMICS: a database of RNA modification pathways. 2017 update

Janusz M. Bujnicki, Valérie de Crécy-Lagard, Robert Ross, 2017, Nucleic Acids Res..

RoboOligo: software for mass spectrometry data to support manual and de novo sequencing of post-transcriptionally modified ribonucleic acids

P. Limbach, J. Alfonzo, K. Gaston, 2015, Nucleic acids research.

Ionizing radiation and chemical oxidant exposure impacts on Cryptococcus neoformans transfer RNAs

Manasses Jora, P. Limbach, B. Addepalli, 2022, PloS one.

tRNA Modification Profiles and Codon-Decoding Strategies in Methanocaldococcus jannaschii

V. de Crécy-Lagard, Priti Thakur, Manasses Jora, 2019, Journal of bacteriology.

Evaluating the reproducibility of quantifying modified nucleosides from ribonucleic acids by LC-UV-MS.

P. Limbach, Susan P. Russell, 2013, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Formation of m2G6 in Methanocaldococcus jannaschii tRNA catalyzed by the novel methyltransferase Trm14

J. Perona, N. Reich, P. Limbach, 2011, Nucleic acids research.

Agmatidine, a modified cytidine in the anticodon of archaeal tRNAIle, base pairs with adenosine but not with guanosine

D. Söll, P. Blum, P. Limbach, 2010, Proceedings of the National Academy of Sciences.

Mass spectrometry-based detection of transfer RNAs by their signature endonuclease digestion products.

P. Limbach, Mahmud Hossain, 2006, RNA.

Stable isotope labeling for matrix-assisted laser desorption/ionization mass spectrometry and post-source decay analysis of ribonucleic acids.

P. Limbach, B. Berhane, 2003, Journal of mass spectrometry : JMS.

Mass spectrometry of the fifth nucleoside: a review of the identification of pseudouridine in nucleic acids.

P. Limbach, A. Durairaj, 2008, Analytica chimica acta.

Novel ribonuclease activity of cusativin from Cucumis sativus for mapping nucleoside modifications in RNA

Priti Thakur, P. Limbach, B. Addepalli, 2017, Analytical and Bioanalytical Chemistry.

Downregulation of the FTO m6A RNA demethylase promotes EMT-mediated progression of epithelial tumors and sensitivity to Wnt inhibitors

C. Sotiriou, C. Desmedt, K. Willard-Gallo, 2021, Nature Cancer.

Identification of a Novel Epoxyqueuosine Reductase Family by Comparative Genomics

Rémi Zallot, Wei-Hung Chen, V. de Crécy-Lagard, 2017, ACS chemical biology.

Enhanced Detection of Post-Transcriptional Modifications Using a Mass-Exclusion List Strategy for RNA Modification Mapping by LC-MS/MS

P. Limbach, Xiaoyu Cao, 2015, Analytical chemistry.

Abundances of transfer RNA modifications and transcriptional levels of tRNA-modifying enzymes are sex-associated in mosquitoes.

P. Limbach, J. Benoit, Melissa Kelley, 2022, Insect biochemistry and molecular biology.

Abundances of transfer RNA modifications and transcriptional levels for tRNA-modifying enzymes are sex-specific in mosquitoes

P. Limbach, J. Benoit, Melissa Kelley, 2021, bioRxiv.

Ribosomes bind leaderless mRNA in Escherichia coli through recognition of their 5'-terminal AUG.

J. E. Brock, P. Limbach, Patrick A Limbach, 2008, RNA.

Oxidative Damage to RNA is Altered by the Presence of Interacting Proteins or Modified Nucleosides

Manasses Jora, P. Limbach, B. Addepalli, 2021, Frontiers in Molecular Biosciences.

Preferential import of queuosine-modified tRNAs into Trypanosoma brucei mitochondrion is critical for organellar protein synthesis

P. Limbach, M. A. Rubio, J. Alfonzo, 2021, Nucleic acids research.

Pseudouridine in the Anticodon of Escherichia coli tRNATyr(QΨA) Is Catalyzed by the Dual Specificity Enzyme RluF*

P. Limbach, B. Addepalli, 2016, The Journal of Biological Chemistry.

A metastable rRNA junction essential for bacterial 30S biogenesis

Wade W. Grabow, L. Jaeger, S. Woodson, 2018, Nucleic acids research.

Flow manipulation for sweeping with a cationic surfactant in microchip capillary electrophoresis.

W. Heineman, P. Limbach, William R Heineman, 2007, Journal of chromatography. A.

Multiple Enzymatic Digestions and Ion Mobility Separation Improve Quantification of Bacterial Ribosomal Proteins by Data Independent Acquisition Liquid Chromatography−Mass Spectrometry

P. Limbach, K. Gaston, Romel P Dator, 2014, Analytical chemistry.

In vivo X-ray footprinting of pre-30S ribosomes reveals chaperone-dependent remodeling of late assembly intermediates.

S. Woodson, P. Limbach, Romel P Dator, 2013, Molecular cell.

Chemical Amination/Imination of Carbonothiolated Nucleosides During RNA Hydrolysis

Manasses Jora, Ruoxia Zhao, Scott Abernathy, 2020, Angewandte Chemie.

Chemical amination/imination of carbonothiolated nucleosides during RNA hydrolysis.

Manasses Jora, Ruoxia Zhao, Scott Abernathy, 2020, Angewandte Chemie.

On-line sample preconcentration by sweeping with dodecyltrimethylammonium bromide in capillary zone electrophoresis.

W. Heineman, P. Limbach, K. Wehmeyer, 2006, Journal of chromatography. A.

Proteomic, Microarray, and Signature-Tagged Mutagenesis Analyses of Anaerobic Pseudomonas aeruginosa at pH 6.5, Likely Representing Chronic, Late-Stage Cystic Fibrosis Airway Conditions

M. Lieberman, D. Hunt, D. Hassett, 2008, Journal of bacteriology.

Applications and Advantages of Stable Isotope Phosphate Labeling of RNA in Mass Spectrometry

P. Limbach, Kayla M Borland, 2017, Topics in Current Chemistry.

Essentiality of threonylcarbamoyladenosine (t6A), a universal tRNA modification, in bacteria

Y. Bessho, J. Armengaud, P. Limbach, 2015, Molecular microbiology.

Evolutionary insights into Trm112-methyltransferase holoenzymes involved in translation between archaea and eukaryotes

V. de Crécy-Lagard, M. Graille, Nathalie Ulryck, 2018, Nucleic acids research.

Yeast Trm7 interacts with distinct proteins for critical modifications of the tRNAPhe anticodon loop.

A. Hopper, E. Phizicky, P. Limbach, 2012, RNA.

Essentiality of threonylcarbamoyladenosine (t[superscript 6]A), a universal tRNA modification, in bacteria

Y. Bessho, J. Armengaud, P. Limbach, 2015 .

Identification of the mass-silent post-transcriptionally modified nucleoside pseudouridine in RNA by matrix-assisted laser desorption/ionization mass spectrometry.

P. Limbach, K. Patteson, L. Rodicio, 2001, Nucleic acids research.

Detection of RNA nucleoside modifications with the uridine-specific ribonuclease MC1 from Momordica charantia

P. Limbach, Nicholas P. Lesner, Balasubrahmanym Addepalli, 2015, RNA.

m6A RNA methylation orchestrates transcriptional dormancy during developmental pausing

M. Ramalho-Santos, P. Limbach, E. Collignon, 2023, bioRxiv.

Application of fractional mass for the identification of peptide-oligonucleotide cross-links by mass spectrometry.

P. Limbach, Patrick A Limbach, Soheil Pourshahian, 2008, Journal of mass spectrometry : JMS.

Experimental determination of the number of trapped ions, detection limit, and dynamic range in Fourier transform ion cyclotron resonance mass spectrometry

P. Limbach, A. Marshall, P. Grosshans, 1993 .

Study of injection bias in a simple hydrodynamic injection in microchip CE

W. Heineman, P. Limbach, William R Heineman, 2007, Electrophoresis.

The use of mass spectrometry in genomics.

Zhaojing Meng, P. Limbach, Z. Meng, 2004, Biomolecular engineering.

RNAModMapper: RNA Modification Mapping Software for Analysis of Liquid Chromatography Tandem Mass Spectrometry Data.

Xiaoyu Cao, P. Limbach, Peter A. Lobue, 2017, Analytical chemistry.

Investigation of Methods Suitable for the Matrix-Assisted Laser Desorption/Ionization Mass Spectrometric Analysis of Proteins from Ribonucleoprotein Complexes

P. Limbach, Moo-Jin Suh, Moo-jin Suh, 2004, European journal of mass spectrometry.

Molecular mass measurement of intact ribonucleic acids via electrospray ionization quadrupole mass spectrometry

P. Limbach, P. Crain, J. McCloskey, 1995, Journal of the American Society for Mass Spectrometry.

Enhanced machining of micron-scale features in microchip molding masters by CNC milling

Douglas Hurd, Patrick A. Limbach, Justin S. Mecomber, 2005 .

Matrix‐Assisted Laser Desorption/Ionization

P. Limbach, Mahmud Hossain, 2012 .

Mass Spectrometry of Nucleosides and Nucleic Acids

P. Limbach, J. Banoub, 2009 .

Improved application of RNAModMapper - An RNA modification mapping software tool - For analysis of liquid chromatography tandem mass spectrometry (LC-MS/MS) data.

Patrick A. Limbach, Manasses Jora, Scott Abernathy, 2019, Methods.

Sequence analysis of peptide:oligonucleotide heteroconjugates by electron capture dissociation and electron transfer dissociation

P. Limbach, Kady L. Krivos, 2010, Journal of the American Society for Mass Spectrometry.

Principles of Proteomics

P. Limbach, Lianji Jin, L. Rodicio, 2007 .

Dynamic queuosine changes in tRNA couple nutrient levels to codon choice in Trypanosoma brucei

Ruoxia Zhao, P. Limbach, M. A. Rubio, 2021, Nucleic acids research.

Comparing polyelectrolyte multilayer‐coated PMMA microfluidic devices and glass microchips for electrophoretic separations

W. Heineman, H. Halsall, C. Ahn, 2009, Electrophoresis.

Encyclopedia of Spectroscopy and Spectrometry, 2nd Edition

A. M. Pollard, A. D. Bain, Jimmy D Bell, 2010 .

A Comparison of MALDI Matrices

P. Limbach, Mahmud Hossain, 2012 .

Characterization and performance of injection molded poly(methylmethacrylate) microchips for capillary electrophoresis.

W. Heineman, C. Ahn, P. Limbach, 2007, Journal of chromatography. A.

Protein‐aptamer binding studies using microchip affinity capillary electrophoresis

W. Heineman, P. Limbach, K. Wehmeyer, 2008, Electrophoresis.

Diversity of Archaeosine Synthesis in Crenarchaeota Diversity of Archaeosine Synthesis in Crenarchaeota

M. Bailly, P. Limbach, V. Crécy-Lagard, 2022 .

Silver cluster interferences in matrix-assisted laser desorption/ionization (MALDI) mass spectrometry of nonpolar polymers

P. Limbach, K. Owens, S. Hanton, 2001, Journal of the American Society for Mass Spectrometry.

Covalent immobilization of proteases and nucleases to poly(methylmethacrylate)

Justin S. Mecomber, P. Limbach, Patrick A Limbach, 2003, Analytical and bioanalytical chemistry.

Limited proteolysis analysis of the ribosome is affected by subunit association.

P. Limbach, Moo-Jin Suh, Daisy-Malloy Hamburg, 2009, Biopolymers.

Interactions between sodium dodecyl sulfate micelles and peptides during matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) of proteolytic digests

P. Limbach, R. Tummala, K. Green-church, 2005, Journal of the American Society for Mass Spectrometry.

Serum protein profiling using surfactant-aided matrix-assisted laser desorption/ionization mass spectrometry

P. Limbach, R. Tummala, 2005 .

Bioengineering Novel Chimeric microRNA-34a for Prodrug Cancer Therapy: High-Yield Expression and Purification, and Structural and Functional Characterization

K. Lam, P. Limbach, B. Addepalli, 2015, The Journal of Pharmacology and Experimental Therapeutics.

Gas-phase hydrogen/deuterium exchange of positively charged mononucleotides by use of Fourier-transform ion cyclotron resonance mass spectrometry

Michael A. Freitas, P. Limbach, A. Marshall, 2001, Journal of the American Society for Mass Spectrometry.

Characterization of oligonucleotides and nucleic acids by mass spectrometry.

P. Limbach, P. Crain, J. McCloskey, 1995, Current opinion in biotechnology.

Improving CMC-derivatization of pseudouridine in RNA for mass spectrometric detection.

P. Limbach, A. Durairaj, 2008, Analytica chimica acta.

Mass spectrometry of RNA: linking the genome to the proteome.

P. Limbach, Z. Meng, 2006, Briefings in functional genomics & proteomics.

The t6A modification acts as a positive determinant for the anticodon nuclease PrrC, and is distinctively nonessential in Streptococcus mutans

S. Shuman, P. Limbach, V. Crécy-Lagard, 2018, RNA biology.

Developing limited proteolysis and mass spectrometry for the characterization of ribosome topography

P. Limbach, Soheil Pourshahian, Moo-jin Suh, 2007, Journal of the American Society for Mass Spectrometry.

Association of the 17-kDa extrinsic protein with photosystem II in higher plants.

P. Limbach, L. Sallans, G. Meades, 2005, Biochemistry.

MASS SPECTROMETRY OF RNA

P. Limbach, Z. Meng, 2008 .

Attomol-level quantification of chemically modified ribonucleosides enabled by capillary porous graphitic carbon columns in nano LC-MS

S. Leidel, P. Limbach, L. P. Sarin, 2017, bioRxiv.

Mapping Post-Transcriptional Modifications onto Transfer Ribonucleic Acid Sequences by Liquid Chromatography Tandem Mass Spectrometry

P. Limbach, Robert L. Ross, Xiaoyu Cao, 2017, Biomolecules.

Estimation of pK(a) values using microchip capillary electrophoresis and indirect fluorescence detection.

H. B. Halsall, W. Heineman, H. Halsall, 2005, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

MODOMICS: a database of RNA modification pathways. 2017 update

Tomasz K. Wirecki, J. Bujnicki, P. Limbach, 2017, Nucleic Acids Res..

Distinct substrate specificities of the human tRNA methyltransferases TRMT10A and TRMT10B

Manasses Jora, P. Limbach, J. Jackman, 2019, RNA.

Novel Chimeric microRNA-34 a for Prodrug Cancer Therapy : High-Yield Expression and Purification , and Structural and Functional Characterization s

K. Lam, P. Limbach, B. Addepalli, 2015 .

Proteomic, Microarray, and Signature-Tagged Mutagenesis Analyses of Anaerobic Pseudomonas aeruginosa at pH 6.5, Likely Representing Chronic, Late-Stage Cystic Fibrosis Airway Conditions

M. Lieberman, D. Hunt, D. Hassett, 2008, Journal of Bacteriology.

Minimizing 18O/16O back-exchange in the relative quantification of ribonucleic acids.

P. Limbach, Colette M. Castleberry, R. Baldauff, 2009, Journal of mass spectrometry : JMS.

An anticodon sequence mutant of Escherichia coli initiator tRNA: possible importance of a newly acquired base modification next to the anticodon on its activity in initiation

P. Limbach, J. McCloskey, U. RajBhandary, 1995, Journal of bacteriology.

m6A RNA methylation orchestrates transcriptional dormancy during paused pluripotency

M. Ramalho-Santos, P. Limbach, E. Collignon, 2023, Nature Cell Biology.

Retrograde nuclear transport from the cytoplasm is required for tRNATyr maturation in T. brucei

P. Limbach, M. A. Rubio, J. Alfonzo, 2018, RNA biology.

Agmatidine, a modified cytidine in the anticodon of archaeal tRNAIle, base pairs with adenosine but not with guanosine

D. Söll, P. Blum, P. Limbach, 2010, Proceedings of the National Academy of Sciences.

Characterizing Benzo[a]pyrene Adducts in Transfer RNAs Using Liquid Chromatography Coupled with Tandem Mass Spectrometry (LC-MS/MS)

P. Limbach, Cassandra Herbert, Balasubrahmanyam Addepalli, 2023, Biomedicines.

Ion trajectories in an electrostatic ion guide for external ion source fourier transform ion cyclotron resonance mass spectrometry

J. Marto, P. Limbach, A. Marshall, 1995, Journal of the American Society for Mass Spectrometry.

Parallel separations using capillary electrophoresis on a multilane microchip with multiplexed laser‐induced fluorescence detection

W. Heineman, P. Limbach, A. Piruska, 2010, Electrophoresis.

Functional microfabricated sample targets for matrix-assisted laser desorption/ionization mass spectrometry analysis of ribonucleic acids.

P. Limbach, B. Berhane, 2003, Analytical Chemistry.

Analytical performance of polymer-based microfluidic devices fabricated by computer numerical controlled machining.

Justin S. Mecomber, Doug Hurd, W. Heineman, 2006, Analytical chemistry.