Q. Gong

发表

Alternative Splicing and Polyadenylation Contribute to the Generation of hERG1 C-terminal Isoforms*

Q. Gong, Matthew R Stump, A. Dunn, 2010, The Journal of Biological Chemistry.

Regulation of Kv11.1 Isoform Expression by Polyadenylate Binding Protein Nuclear 1

Q. Gong, Matthew R Stump, Zhengfeng Zhou, 2021, International journal of molecular sciences.

Upregulation of functional Kv11.1a isoform expression by modified U1 small nuclear RNA.

Q. Gong, Matthew R Stump, Zhengfeng Zhou, 2018, Gene.

Regulation of Isoform Expression by Blocking Polyadenylation Signal Sequences with Morpholinos.

Q. Gong, Zhengfeng Zhou, 2017, Methods in molecular biology.

Identification of Kv11.1 Isoform Switch as a Novel Pathogenic Mechanism of Long-QT Syndrome

Q. Gong, Matthew R Stump, Vivianne Deng, 2014, Circulation. Cardiovascular genetics.

Upregulation of functional Kv11.1 isoform expression by inhibition of intronic polyadenylation with antisense morpholino oligonucleotides.

Q. Gong, Matthew R Stump, Zhengfeng Zhou, 2014, Journal of molecular and cellular cardiology.

Isoform-Specific Dominant-Negative Effects Associated with hERG1 G628S Mutation in Long QT Syndrome

Q. Gong, Matthew R Stump, Zhengfeng Zhou, 2012, PloS one.

Nonsense Mutations in hERG Cause a Decrease in Mutant mRNA Transcripts by Nonsense-Mediated mRNA Decay in Human Long-QT Syndrome

B. Horne, G. Vincent, Q. Gong, 2007, Circulation.

Role of glycosylation in cell surface expression and stability of HERG potassium channels.

C. January, C. Anderson, Q. Gong, 2002, American journal of physiology. Heart and circulatory physiology.

Mechanism of block and identification of the verapamil binding domain to HERG potassium channels.

C. January, J. Makielski, Q. Gong, 1999, Circulation research.

Cocaine blocks HERG, but not KvLQT1+minK, potassium channels.

C. January, Q. Gong, Zhengfeng Zhou, 2001, Molecular pharmacology.

Blockage of the HERG human cardiac K+ channel by the gastrointestinal prokinetic agent cisapride.

Qiuming Gong, C. January, Q. Gong, 1997, American journal of physiology. Heart and circulatory physiology.

Properties of HERG channels stably expressed in HEK 293 cells studied at physiological temperature.

C. January, G. Robertson, J. Makielski, 1998, Biophysical journal.

Block of HERG Potassium Channels by the Antihistamine Astemizole and its Metabolites Desmethylastemizole and Norastemizole

C. January, Q. Gong, Zhengfeng Zhou, 1999, Journal of cardiovascular electrophysiology.

Mechanisms of Pharmacological Rescue of Trafficking-defective hERG Mutant Channels in Human Long QT Syndrome*

Melanie A. Jones, Q. Gong, Zhengfeng Zhou, 2006, Journal of Biological Chemistry.

Regulation of Rat Pyruvate Carboxylase Gene Expression by Alternate Promoters during Development, in Genetically Obese Rats and in Insulin-secreting Cells

J. Wallace, Q. Gong, S. Jitrapakdee, 1998, The Journal of Biological Chemistry.

Functional Analysis of Two Promoters for the Human Mitochondrial Glycerol Phosphate Dehydrogenase Gene*

Q. Gong, L. Brown, M. MacDonald, 2000, The Journal of Biological Chemistry.

Recurrent intrauterine fetal loss due to near absence of HERG: clinical and functional characterization of a homozygous nonsense HERG Q1070X mutation.

A. Wilde, Q. Gong, Zhengfeng Zhou, 2008, Heart rhythm.

Stimulation of insulin release by glyceraldehyde may not be similar to glucose.

F. Chaplen, Q. Gong, Heather Drought, 2006, Archives of biochemistry and biophysics.

Molecular Screening n Unexplained Sudden Death

P. Tran, Q. Gong, J. Titus, 2016 .

LQT2 nonsense mutations generate trafficking defective NH2-terminally truncated channels by the reinitiation of translation.

Q. Gong, Matthew R Stump, Zhengfeng Zhou, 2013, American journal of physiology. Heart and circulatory physiology.

Multiple Splicing Defects Caused by Herg Splice Site Mutation 2592ϩ1gͼa Associated with Long Qt Syndrome

Q. Gong, Matthew R Stump, Zhengfeng Zhou, 2022 .

Pharmacological rescue of trafficking defective HERG channels formed by coassembly of wild-type and long QT mutant N470D subunits.

C. January, C. Anderson, Q. Gong, 2004, American Journal of Physiology. Heart and Circulatory Physiology.

Defective assembly and trafficking of mutant HERG channels with C-terminal truncations in long QT syndrome.

Q. Gong, Zhengfeng Zhou, David R Keeney, 2004, Journal of molecular and cellular cardiology.

LQT 2 Nonsense Mutations Generate Trafficking Defective N-Terminally 1 Truncated Channels by the Reinitiation of Translation 2

Q. Gong, Matthew R Stump, Zhengfeng Zhou, 2013 .

Blockage of the HERG human cardiac K+ channel by the gastrointestinal prokinetic agent cisapride.

C. January, Q. Gong, Z. Zhou, 1997, The American journal of physiology.

Nonsense-mediated mRNA decay caused by a frameshift mutation in a large kindred of type 2 long QT syndrome.

G. Vincent, Q. Gong, Zhengfeng Zhou, 2011, Heart rhythm.

Inhibition of nonsense-mediated mRNA decay by antisense morpholino oligonucleotides restores functional expression of hERG nonsense and frameshift mutations in long-QT syndrome.

Q. Gong, Zhengfeng Zhou, Matthew R. Stump, 2011, Journal of molecular and cellular cardiology.

A splice site mutation in hERG leads to cryptic splicing in human long QT syndrome.

A. Moss, D. Tester, M. Ackerman, 2008, Journal of molecular and cellular cardiology.

Early LQT2 nonsense mutation generates N-terminally truncated hERG channels with altered gating properties by the reinitiation of translation.

Q. Gong, Zhengfeng Zhou, Matthew R. Stump, 2012, Journal of molecular and cellular cardiology.

Nonsense-Mediated mRNA Decay of hERG Mutations in Long QT Syndrome.

Q. Gong, Zhengfeng Zhou, 2018, Methods in molecular biology.

Position of premature termination codons determines susceptibility of hERG mutations to nonsense-mediated mRNA decay in long QT syndrome.

Q. Gong, Zhengfeng Zhou, Matthew R. Stump, 2014, Gene.

Most LQT2 Mutations Reduce Kv11.1 (hERG) Current by a Class 2 (Trafficking-Deficient) Mechanism

C. January, D. Tester, M. Ackerman, 2006, Circulation.

Long QT Syndrome:

C. January, Q. Gong, Zhengfeng Zhou, 2000, Journal of cardiovascular electrophysiology.

Postmortem molecular screening in unexplained sudden death.

S. Chugh, P. Tran, Q. Gong, 2004, Journal of the American College of Cardiology.

HERG Channel Dysfunction in Human Long QT Syndrome

C. January, Q. Gong, Zhengfeng Zhou, 1998, The Journal of Biological Chemistry.

A Major Role for hERG in Determining Frequency of Reentry in Neonatal Rat Ventricular Myocyte Monolayer

José Jalife, Omer Berenfeld, Makarand Deo, 2010, Circulation research.

Correction of Defective Protein Trafficking of a Mutant HERG Potassium Channel in Human Long QT Syndrome

C. January, Q. Gong, Zhengfeng Zhou, 1999, The Journal of Biological Chemistry.

Degradation of Trafficking-defective Long QT Syndrome Type II Mutant Channels by the Ubiquitin-Proteasome Pathway*

Qiuming Gong, Maurizio Molinari, M. Molinari, 2005, Journal of Biological Chemistry.

Brief Report: Oxidative Stress Mediates Cardiomyocyte Apoptosis in a Human Model of Danon Disease and Heart Failure

K. Frazer, J. I. Izpisúa Belmonte, A. D. Panopoulos, 2015, Stem cells.

Novel mechanism associated with an inherited cardiac arrhythmia: defective protein trafficking by the mutant HERG (G601S) potassium channel.

C. January, M. Furutani, R. Matsuoka, 1999, Circulation.

Regulation of Kv11.1 potassium channel C-terminal isoform expression by the RNA-binding proteins HuR and HuD

Q. Gong, Zhengfeng Zhou, Matthew R. Stump, 2018, The Journal of Biological Chemistry.

Multiple splicing defects caused by hERG splice site mutation 2592+1G>A associated with long QT syndrome.

Q. Gong, Zhengfeng Zhou, Matthew R. Stump, 2011, American journal of physiology. Heart and circulatory physiology.

Defective protein trafficking of HERG K+ channels in human congenital long QT syndrome

C. January, Q. Gong, Zhengfeng Zhou, 2000 .