J. Orchard

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ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile.

Adrian Wiestner, Sarah E Henrickson, Gerald E Marti, 2003, Blood.

ZAP-70 expression and prognosis in chronic lymphocytic leukaemia

Adrian Wiestner, Andreas Rosenwald, L. Staudt, 2004, The Lancet.

V(H) gene analysis of splenic marginal zone lymphomas reveals diversity in mutational status and initiation of somatic mutation in vivo.

D. Oscier, J. Orchard, D. Wright, 2002, Blood.

Response to cladribine in previously treated patients with chronic lymphocytic leukaemia identified by ex vivo assessment of drug sensitivity by DiSC assay

D. Oscier, J. Orchard, A. G. Bosanquet, 1999, British journal of haematology.

ZAP-70 in B cell malignancies

D. Oscier, R. Ibbotson, J. Orchard, 2005, Leukemia & lymphoma.

Autoimmune haemolysis in patients with B-CLL treated with chlorodeoxyadenosine (CDA).

J. Orchard, A. Prentice, H. Myint, 1998, Leukemia & lymphoma.

Divergence from the germ-line sequence in unmutated chronic lymphocytic leukemia is due to somatic mutation rather than polymorphisms.

D. Oscier, Z. Davis, M. Corcoran, 2003, Blood.

ZAP‐70 by flow cytometry: A comparison of different antibodies, anticoagulants, and methods of analysis

D. Oscier, Z. Davis, O. G. Best, 2006, Cytometry. Part B, Clinical cytometry.

D. Oscier, J. Orchard, T. Hamblin, 1995, British journal of haematology.

IN PATIENTS WITH LYMPHOID TUMOURS RECOVERING FROM THE AUTOIMMUNE COMPLICATIONS OF FLUDARABINE, RELAPSE MAY BE TRIGGERED BY CONVENTIONAL CHEMOTHERAPY

D. Oscier, J. Orchard, T. Hamblin, 1998, British journal of haematology.

P2X7 polymorphism and chronic lymphocytic leukaemia: lack of correlation with incidence, survival and abnormalities of chromosome 12

D. Oscier, L. Zhang, A. Chase, 2003, Leukemia.

Pharmacokinetic study of single doses of oral fludarabine phosphate in patients with "low-grade" non-Hodgkin's lymphoma and B-cell chronic lymphocytic leukemia.

T. Lister, D. Oscier, J. Orchard, 1999, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

ZAP-70 methylation status is associated with ZAP-70 expression status in chronic lymphocytic leukemia.

D. Oscier, Z. Davis, M. Corcoran, 2005, Haematologica.

Structural and Functional Features of the B-Cell Receptor in IgG-Positive Chronic Lymphocytic Leukemia

G. Packham, J. Orchard, F. Stevenson, 2006, Clinical Cancer Research.

Multivariate analysis of prognostic factors in CLL: clinical stage, IGVH gene mutational status, and loss or mutation of the p53 gene are independent prognostic factors.

D. Oscier, Z. Davis, M. Corcoran, 2002, Blood.

CD38 expression and immunoglobulin variable region mutations are independent prognostic variables in chronic lymphocytic leukemia, but CD38 expression may vary during the course of the disease.

D. Oscier, Z. Davis, R. Ibbotson, 2002, Blood.

Dysregulation of cyclin dependent kinase 6 expression in splenic marginal zone lymphoma through chromosome 7q translocations

S. Scherer, L. Tsui, D. Oscier, 1999, Oncogene.

Severe Intravascular Haemolysis in a Renal Transplant Recipient due to Anti‐B of Donor Origin

J. Orchard, C. Darke, N. Young, 1990, Vox sanguinis.

Wiskott-Aldrich syndrome: fatal consequences of splenectomy in an unrecognised attenuated variant.

J. Orchard, G. Standen, R. Hutton, 1990, The British journal of clinical practice.

A subset of t(11;14) lymphoma with mantle cell features displays mutated IgVH genes and includes patients with good prognosis, nonnodal disease.

D. Catovsky, D. Oscier, E. Matutes, 2003, Blood.

Fludarabine and hemolytic anemia in chronic lymphocytic leukemia.

D. Oscier, J. Orchard, T. Hamblin, 1998, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Immunoglobulin V genes and CD38 expression in CLL.

T J Hamblin, D G Oscier, D. Oscier, 2000, Blood.

distinct gene expression profile with unmutated immunoglobulin genes , inferior clinical outcome , and ZAP-70 expression identifies a chronic lymphocytic leukemia subtype

L. Staudt, R. Davis, A. Rosenwald, 2003 .

elderly repertoire chronic lymphocytic leukemia are distinct from those in the healthy Features of the over-expressed V1-69 genes in the unmutated subset of

J. Orchard, K. Potter, C. I. Mockridge, 2013 .

Features of the overexpressed V1-69 genes in the unmutated subset of chronic lymphocytic leukemia are distinct from those in the healthy elderly repertoire.

J. Orchard, F. Stevenson, K. Potter, 2003, Blood.

Fludarabine is effective in the treatment of splenic lymphoma with villous lymphocytes

D. Oscier, J. Orchard, S. Bolam, 1997, British journal of haematology.

The bioavailability of oral fludarabine phosphate is unaffected by food.

D. Oscier, J. Orchard, S. Johnson, 2001, The hematology journal : the official journal of the European Haematology Association.

Prognostic Factors in the UK LRF CLL4 Trial.

D. Catovsky, R. Wade, D. Oscier, 2005 .

ZAP-70 by Flow Cytometry: Comparison of Methodologies, and with IgVH Mutational and ZAP-70 Methylation Status.

D. Oscier, O. G. Best, R. Ibbotson, 2005 .

A patient with myeloma who still has pure red cell aplasia despite the most intensive immune modulation.

J. Orchard, T. Hamblin, H. Myint, 1997, Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis.

The Natural History of Mutated, Stage AO Chronic Lymphocytic Leukemia.

L. Staudt, A. Wiestner, D. Oscier, 2004 .

gene expression profile unmutated immunoglobulin genes, inferior clinical outcome, and distinct ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with

L. Staudt, R. Davis, A. Rosenwald, 2013 .

Gender as a Prognostic Factor in CLL. Biological Pointers to the Improved Outcome of Women.

D. Catovsky, D. Oscier, E. Matutes, 2004 .

In Chronic Lymphocytic Leukemia Females Survive for Longer Than Males Even in Patients with Unmutated Immunoglobulin Genes.

D. Oscier, R. Ibbotson, J. Orchard, 2004 .