P. Collins

发表

Construction of a Shape-Diverse Fragment Set: Design, Synthesis and Screen against Aurora-A Kinase.

Adam Nelson, F. von Delft, Stuart L. Warriner, 2019, Chemistry.

Gentle, fast and effective crystal soaking by acoustic dispensing

J. Ng, F. von Delft, J. Brandão-Neto, 2016, bioRxiv.

Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-β-lactamases

Samuel T. Cahill, F. von Delft, P. Collins, 2018, Bioorganic & medicinal chemistry.

Rapid optimisation of fragments and hits to lead compounds from screening of crude reaction mixtures

F. von Delft, J. Murray, R. Hubbard, 2020, Communications Chemistry.

Galectin-3 inhibitors: a patent review (2008–present)

K. Bum-Erdene, P. Collins, H. Blanchard, 2014, Expert opinion on therapeutic patents.

Synthesis and Demonstration of the Biological Relevance of sp3‐rich Scaffolds Distantly Related to Natural Product Frameworks

Adam Nelson, Frank von Delft, Daniel J Foley, 2017, Chemistry.

Rapid optimisation of fragments and hits to lead compounds from screening of crude reaction mixtures

F. von Delft, J. Murray, R. Hubbard, 2020, Communications Chemistry.

Towards understanding the functional role of the glycosyltransferases involved in the biosynthesis of Moraxella catarrhalis lipooligosaccharide

P. Hitchen, A. Dell, H. Morris, 2007, The FEBS journal.

Biochemical analysis of Lgt3, a glycosyltransferase of the bacterium Moraxella catarrhalis.

J. Tiralongo, P. Collins, Jennifer C. Wilson, 2010, Biochemical and biophysical research communications.

An Unusual Carbohydrate Conformation is Evident in Moraxella catarrhalis Oligosaccharides

P. Collins, M. Frank, Jennifer C. Wilson, 2015, Molecules.

Identification of a novel glycosyltransferase involved in LOS biosynthesis of Moraxella catarrhalis.

P. Collins, Jennifer C. Wilson, I. Peak, 2006, Carbohydrate research.

Galectin‐3‐Binding Glycomimetics that Strongly Reduce Bleomycin‐Induced Lung Fibrosis and Modulate Intracellular Glycan Recognition

S. Oredsson, P. Collins, R. Pieters, 2016, Chembiochem : a European journal of chemical biology.

Slow diffusion of lactose out of galectin-3 crystals monitored by X-ray crystallography: possible implications for ligand-exchange protocols.

P. Collins, H. Blanchard, K. Hidari, 2007, Acta crystallographica. Section D, Biological crystallography.

Investigation into the Feasibility of Thioditaloside as a Novel Scaffold for Galectin‐3‐Specific Inhibitors

K. Bum-Erdene, P. Collins, I. Gagarinov, 2013, Chembiochem : a European journal of chemical biology.

Taloside Inhibitors of Galectin‐1 and Galectin‐3

P. Collins, H. Blanchard, U. Nilsson, 2012, Chemical biology & drug design.

Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches.

Kristian Birchall, Frank von Delft, Anja Winter, 2017, ACS chemical biology.

Novel Selective Galectin-3 Antagonists Are Cytotoxic to Acute Lymphoblastic Leukemia.

N. Heisterkamp, J. Groffen, K. Bum-Erdene, 2022, Journal of medicinal chemistry.

A Selective Galactose-Coumarin-Derived Galectin-3 Inhibitor Demonstrates Involvement of Galectin-3-glycan Interactions in a Pulmonary Fibrosis Model.

P. Collins, H. Blanchard, A. MacKinnon, 2016, Journal of medicinal chemistry.

Achieving Efficient Fragment Screening at XChem Facility at Diamond Light Source.

F. von Delft, J. Brandão-Neto, N. Pearce, 2021, Journal of visualized experiments : JoVE.

Structure-guided fragment-based drug discovery at the synchrotron: screening binding sites and correlations with hotspot mapping

T. Blundell, F. von Delft, C. Radoux, 2019, Philosophical Transactions of the Royal Society A.

The XChemExplorer graphical workflow tool for routine or large-scale protein–ligand structure determination

Patrick Collins, Frank von Delft, Romain Talon, 2017, Acta crystallographica. Section D, Structural biology.

Small Molecule Antagonists of the Interaction between the Histone Deacetylase 6 Zinc-Finger Domain and Ubiquitin.

H. Ouyang, F. von Delft, C. Arrowsmith, 2017, Journal of medicinal chemistry.

Galectin-3 interactions with glycosphingolipids.

K. Bum-Erdene, P. Collins, H. Blanchard, 2014, Journal of molecular biology.

Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model.

P. Collins, H. Blanchard, S. Ralph, 2010, Cancer letters.

Identification of a capsular polysaccharide from Moraxella bovis.

P. Hitchen, A. Dell, H. Morris, 2005, Carbohydrate research.

Aromatic heterocycle galectin-1 interactions for selective single-digit nM affinity ligands

S. Oredsson, P. Collins, H. Blanchard, 2018, RSC advances.

Achieving a Good Crystal System for Crystallographic X-Ray Fragment Screening.

F. von Delft, J. Brandão-Neto, P. Collins, 2018, Methods in enzymology.

Bispecific repurposed medicines targeting the viral and immunological arms of COVID-19

M. Swindells, D. Stuart, A. Hopkins, 2021, Scientific Reports.

Achieving a Good Crystal System for Crystallographic X-Ray Fragment Screening.

F. von Delft, J. Brandão-Neto, P. Collins, 2018, Methods in enzymology.

Investigation into the Feasibility of Thioditaloside as a Novel Scaffold for Galectin‐3‐Specific Inhibitors

K. Bum-Erdene, P. Collins, I. Gagarinov, 2013, Chembiochem : a European journal of chemical biology.

Small Molecule Antagonists of the Interaction between the Histone Deacetylase 6 Zinc-Finger Domain and Ubiquitin.

F. von Delft, C. Arrowsmith, M. Schapira, 2017, Journal of medicinal chemistry.