D. Priest

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Sub-nucleosomal Genome Structure Reveals Distinct Nucleosome Folding Motifs

T. Ando, M. Ohno, D. Priest, 2019, Cell.

Disposition of folic acid and its metabolites: A comparison with leucovorin

J. C. Schmitz, D. Priest, R. Stuart, 1994, Clinical pharmacology and therapeutics.

Regulation of carrier-mediated transport of folates and antifolates in methotrexate-sensitive and-resistant leukemia cells.

Y. Assaraf, J. Schornagel, D. Priest, 1997, Advances in enzyme regulation.

The role of folylpolyglutamate synthetase and gamma-glutamyl hydrolase in altering cellular folyl- and antifolylpolyglutamates.

D. Priest, M. Rhee, J. Galivan, 1987, Advances in enzyme regulation.

Relationship of reduced folate changes to inhibition of DNA synthesis induced by methotrexate in L1210 cells in vivo.

F. Sirotnak, D. Priest, M. Bunni, 1989, Cancer research.

Effects of methotrexate on folates in Krebs ascites and L1210 murine leukemia cells.

D. Priest, K. Scanlon, P. Sur, 1986, Cancer letters.

Determination of mouse liver 5-methyltetrahydrofolate concentration and polyglutamate forms.

D. Priest, J. Peters, P. Sur, 1985, Journal of biochemical and biophysical methods.

Tissue folylpolyglutamate chain-length characterization by electrophoresis as thymidylate synthetase-fluorodeoxyuridylate ternary complexes.

D. Priest, C. Baugh, M. T. Doig, 1981, Analytical biochemistry.

Relative affinity of 5,10-methylenetetrahydrofolylpolyglutamates for the Lactobacillus casei thymidylate synthetase-5-fluorodeoxyuridylate binary complex.

D. Priest, M. Mangum, 1981, Archives of biochemistry and biophysics.

A Structurally Altered Human Reduced Folate Carrier with Increased Folic Acid Transport Mediates a Novel Mechanism of Antifolate Resistance*

G. Peters, Y. Assaraf, J. Schornagel, 1998, The Journal of Biological Chemistry.

Re: Folylpolyglutamyl synthetase gene transfer and glioma antifolate sensitivity in culture and in vivo.

Y. Assaraf, D. Priest, G. Jansen, 1999, Journal of the National Cancer Institute.

Differences in constitutive and post-methotrexate folylpolyglutamate synthetase activity in B-lineage and T-lineage leukemia

M. Relling, C. Pui, W. Evans, 1994 .

Biochemical basis for cisplatin and 5-fluorouracil synergism in human ovarian carcinoma cells.

D. Priest, Y. Lu, K. Scanlon, 1986, Proceedings of the National Academy of Sciences of the United States of America.

Response to 5-fluorouracil chemotherapy is modified by dietary folic acid deficiency in Apc(Min/+) mice.

D. Priest, F. Berger, H. Spencer, 2002, Cancer letters.

Resistance to multiple novel antifolates is mediated via defective drug transport resulting from clustered mutations in the reduced folate carrier gene in human leukaemia cell lines.

Y. Assaraf, D. Priest, G. Jansen, 2002, The Biochemical journal.

Superoxide dismutase activities of bovine ocular tissues.

E. Duke, D. Priest, R. Crouch, 1978, Experimental eye research.

Reaction intermediate effects on the spectrophotometric uricase assay.

D. Priest, O. M. Pitts, 1972, Analytical biochemistry.

Comparison of folylpolyglutamate hydrolases of mouse liver, kidney, muscle and brain

D. Priest, C. Veronee, M. T. Doig, 1982, Molecular and Cellular Biochemistry.

Hydrolytic cleavage of methotrexate gamma-polyglutamates by folylpolyglutamyl hydrolase derived from various tumors and normal tissues of the mouse.

F. Sirotnak, D. Priest, L. J. Goutas, 1986, Cancer research.

Enhancement of polyacrylamide gel slice dissolution in hydrogen peroxide by cupric sulfate.

D. Priest, M. T. Doig, H. Donato, 1988, Journal of biochemical and biophysical methods.

Serine transhydroxymethylase: mechanism of aldolase activation by folate.

D. Priest, C. Jones, 1976, Archives of biochemistry and biophysics.

Uricase. Subunit composition and resistance to denaturants.

D. Priest, W. Fish, O. M. Pitts, 1974, Biochemistry.

Electrophoretic assay of folylpolyglutamate synthetase activity.

J. Bertino, D. Priest, J. McGuire, 1981, Journal of biochemical and biophysical methods.

Effect of streptozotocin on erythrocyte and retinal superoxide dismutase

D. Priest, M. Buse, R. Crouch, 1978, Diabetologia.

Impact of schedule on leucovorin potentiation of fluorouracil antitumor activity in dietary folic acid deplete mice.

J. C. Schmitz, D. Priest, K. Raghunathan, 1997, Biochemical pharmacology.

Pharmacokinetics of leucovorin metabolites in human plasma as a function of dose administered orally and intravenously.

J. C. Schmitz, D. Priest, R. Stuart, 1991, Journal of the National Cancer Institute.

Role of folylpolyglutamates in biochemical modulation of fluoropyrimidines by leucovorin.

J. Bertino, D. Niedzwiecki, D. Priest, 1991, Cancer research.

Evidence for involvement of tyrosine phosphorylation in taxol-induced apoptosis in a human ovarian tumor cell line.

K. Bhalla, D. Priest, Y. Liu, 1994, Biochemical pharmacology.

Pharmacokinetic and pharmacodynamic evaluation of the glycinamide ribonucleotide formyltransferase inhibitor AG2034.

H. McLeod, D. Bissett, M. Collier, 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.

Role of substrate depletion in the inhibition of thymidylate biosynthesis by the dihydrofolate reductase inhibitor trimetrexate in cultured hepatoma cells.

G. Maley, F. Maley, D. Priest, 1990, Cancer research.

Differences in constitutive and post-methotrexate folylpolyglutamate synthetase activity in B-lineage and T-lineage leukemia.

M. Relling, C. Pui, D. Priest, 1994, Blood.

Promoter Activation by CII, a Potent Transcriptional Activator from Bacteriophage 186*

I. Dodd, D. Priest, K. Shearwin, 2014, The Journal of Biological Chemistry.

Increased thymidylate synthetase in 5-fluorodeoxyuridine resistant cultured hepatoma cells.

D. Priest, M. T. Doig, B. E. Ledford, 1980, Biochemical pharmacology.

Micro-patterned agarose gel devices for single-cell high-throughput microscopy of E. coli cells

N. Tanaka, D. Priest, Y. Taniguchi, 2017, Scientific Reports.

Uricase reaction intermediate. Mechanism of borate and hydroxide ion catalysis.

D. Priest, O. M. Pitts, 1973, Biochemistry.

Rapid quantitative PCR for determination of relative gene expressions in tissue specimens.

H. Lenz, K. Danenberg, P. Danenberg, 1995, PCR methods and applications.

Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis.

G. Peters, Y. Assaraf, J. Schornagel, 2002, Biochemical pharmacology.

Quinazolines as Inhibitors of Xanthe Oxidase

D. Priest, C. Jones, J. Hynes, 1974 .

Substrate activation with a xanthine oxidase reaction. An alternative to dismutation as an explanation in the chicken liver system.

D. Priest, J. Fisher, 1969, European journal of biochemistry.

A steady-state kinetic investigation of the uricase reaction mechanism.

D. Priest, O. M. Pitts, 1974, Archives of biochemistry and biophysics.

Cell cycle patterns of thymidylate synthetase and 5,10-methylenetetrahydrofolate polyglutamates in cultured mouse hepatoma cells

D. Priest, M. T. Doig, B. E. Ledford, 1982, Experientia.

Multifactorial resistance to 5,10-dideazatetrahydrofolic acid in cell lines derived from human lymphoblastic leukemia CCRF-CEM.

D. Priest, G. P. Beardsley, M. Bunni, 1995, Cancer research.

Modulation of both endogenous folates and thymidine enhance the therapeutic efficacy of thymidylate synthase inhibitors.

C. L. van der Wilt, D. Priest, G. Jansen, 2001, Cancer research.

Response of methylenetetrahydrofolate levels to methotrexate in Krebs ascites cells.

D. Priest, P. Sur, M. T. Doig, 1983, The Biochemical journal.

A centrifugal column assay for thymidylate synthetase using the active site titrant 5-fluoro-2'-deoxyuridylate.

D. Priest, M. T. Doig, C. Alford, 1980, Analytical biochemistry.

The role of cellular folates in the enhancement of activity of the thymidylate synthase inhibitor 10-propargyl-5,8-dideazafolate against hepatoma cells in vitro by inhibitors of dihydrofolate reductase.

D. Priest, M. Bunni, M. Rhee, 1989, The Journal of biological chemistry.

A sensitive assay employing a solid-phase metal chelator to estimate rates of iron accumulation by ferritin.

D. Priest, J. Collawn, W. Fish, 1982, Analytical biochemistry.

Distribution of superoxide dismutase in rat brain

T. N. Thomas, D. Priest, J. W. Zemp, 1976, Journal of neurochemistry.

The effect of methotrexate on the folate coenzyme pools in human hepatoma cells in culture.

D. Priest, J. Whiteley, M. Bunni, 1991, Advances in experimental medicine and biology.

Purification of mouse liver thymidylate synthetase by affinity chromatography using 10-methyl-5,8-dideazafolate as the affinant

D. Priest, J. Hynes, M. T. Doig, 1981, Experientia.

Role of methylenetetrahydrofolate depletion in methotrexate-mediated intracellular thymidylate synthesis inhibition in cultured L1210 cells.

D. Priest, D G Priest, M. Bunni, 1988, Cancer research.

Enzymatic determination of tissue dihydrofolate

D. Priest, J. Peters, P. Sur, 1984 .

Response of mouse hepatoma cell methylenetetrahydrofolate polyglutamates to folate deprivation.

D. Priest, M. T. Doig, M. Mangum, 1983, Biochimica et biophysica acta.

Quantitation of interactions between two DNA loops demonstrates loop domain insulation in E. coli cells

D. Dunlap, I. Dodd, D. Priest, 2014, Proceedings of the National Academy of Sciences.

A radioenzymatic method for the determination of tissue 10-formyltetrahydrofolate.

D. Priest, V. Kesavan, M. T. Doig, 1986, Journal of biochemical and biophysical methods.

Tissue folate polyglutamate chain length determination by electrophoresis as thymidylate synthase-fluorodeoxyuridylate ternary complexes.

D. Priest, M. T. Doig, 1986, Methods in enzymology.

Electrophoretic identification of poly-gamma-glutamate chain-lengths of 5,10-methylenetetrahydrofolate using thymidylate synthetase complexes.

D. Priest, M. T. Doig, K. Happel, 1980, Journal of biochemical and biophysical methods.

The role of multidrug resistance proteins MRP1, MRP2 and MRP3 in cellular folate homeostasis.

G. Peters, Y. Assaraf, A. Veerman, 2003, Biochemical pharmacology.

Fluoropyrimidines by Leucovorin Role of Folylpolyglutamates in Biochemical Modulation of Updated

James T. Lin, D. Niedzwiecki, D. Priest, 2006 .

CCRF-CEM Cell Lines Derived from Human Lymphoblastic Leukemia Multifactorial Resistance to 5 , 10-Dideazatetrahydrofolic Acid in Updated Version

Jennifer, D. Priest, Bárbara, 2006 .

A Comparison of Hplc and Ternary Complex-Based Assays of Tissue Reduced Folates

D. Priest, M. Bunni, M. Rhee, 1992 .

A sensitive radioenzymatic assay for (S)-5-formyltetrahydrofolate.

J. C. Schmitz, D. Priest, J. Whiteley, 1991, Analytical biochemistry.

Human red blood cell-mediated metabolism of leucovorin [(R,S)5-formyltetrahydrofolate].

D. Priest, M. Bunni, 1991, Archives of biochemistry and biophysics.

Radioenzymatic determination of subpicomole quantities of folic acid and dihydrofolate based on differential reduction by dihydrofolate reductase

D. Priest, V. Kesavan, M. T. Doig, 1986 .

Effects of growth rate and methotrexate on folate polyglutamates and folylpolyglutamate hydrolase activity in Krebs ascites cells.

D. Priest, P. Sur, M. T. Doig, 1986, Biochemistry and cell biology = Biochimie et biologie cellulaire.

Live cell dynamics of the NF-Y transcription factor

R. Mantovani, D. Priest, A. Bernardini, 2021, Scientific Reports.

Fluorescence fluctuation spectroscopy: an invaluable microscopy tool for uncovering the biophysical rules for navigating the nuclear landscape.

Jieqiong Lou, D. Priest, Elizabeth Hinde, 2019, Biochemical Society transactions.

Cancer cells activate p53 in response to 10-formyltetrahydrofolate dehydrogenase expression.

D. Priest, S. Krupenko, N. Krupenko, 2005, The Biochemical journal.

One-step cloning and chromosomal integration of DNA.

D. Endy, I. Dodd, D. Priest, 2013, ACS synthetic biology.

Photosensitizer catalyzed oxidation of urate as a model for uricase

D. Priest, T. Conley, 1980 .

Nucleosome-level 3D organization of the genome.

M. Ohno, D. Priest, Y. Taniguchi, 2018, Biochemical Society transactions.

Hi-CO: 3D genome structure analysis with nucleosome resolution

T. Ando, M. Ohno, D. Priest, 2021, Nature Protocols.

Role of Multidrug Resistance Proteins (MRP) in Resistance to Antifolates and Folate Homeostasis

M. Kool, Y. Assaraf, D. Priest, 2002 .

Disposition of leucovorin and its metabolites in the plasma, intestinal epithelium, and intraperitoneal L1210 cells of methotrexate-pretreated mice

F. Sirotnak, D. Priest, M. Bunni, 2004, Cancer Chemotherapy and Pharmacology.

Multiple mechanisms of resistance to polyglutamatable and lipophilic antifolates in mammalian cells: role of increased folylpolyglutamylation, expanded folate pools, and intralysosomal drug sequestration.

G. Peters, Y. Assaraf, D. Priest, 1999, Molecular pharmacology.

Severe folate restriction results in depletion of and alteration in the composition of the intracellular folate pool, moderate sensitization to methotrexate and trimetrexate, upregulation of endogenous DHFR activity, and overexpression of metallothionein II and folate receptor alpha that, upon folat

Wei Zhu, D. Priest, M. Bunni, 2002, Journal of experimental therapeutics & oncology.

Pharmacokinetic and Pharmacodynamic Evaluation of the Glycinamide Ribonucleotide Formyltransferase

John D. Roberts, H. McLeod, D. Bissett, 2000 .

Pharmacokinetic and Pharmacodynamic Evaluation of the Glycinamide Ribonucleotide Formyltransferase Inhibitor AG 2034 1

John D. Roberts, H. McLeod, D. Bissett, 2000 .

Disposition of leucovorin and its metabolites in dietary folic acid-deplete mice – comparison between tumor, liver and plasma

J. C. Schmitz, D. Priest, K. Raghunathan, 1997, Cancer Chemotherapy and Pharmacology.

Effects of antisense-based folypoly-gamma-glutamate synthetase down-regulation on reduced folates and cellular proliferation in CCRF-CEM cells.

D. Priest, M. Bunni, J. Barredo, 1998, Biochemical pharmacology.

Quantitation of the DNA tethering effect in long-range DNA looping in vivo and in vitro using the Lac and lambda repressors

D. Dunlap, I. Dodd, D. Priest, 2022 .

Folate metabolites as modulators of antitumor drug activity.

J. C. Schmitz, D. Priest, M. Bunni, 1993, Advances in experimental medicine and biology.

Accumulation of tetrahydrofolates in human plasma after leucovorin administration

D. Priest, R. Stuart, M. Bunni, 2004, Cancer Chemotherapy and Pharmacology.

Folates as Chemotherapeutic Modulators

D. Priest, M. Bunni, J. Barredo, 1999 .

Leucovorin as a prodrug.

J. C. Schmitz, D. Priest, T. Walle, 1993, Advances in experimental medicine and biology.

Enzyme kinetics. Systematic generation of valid King-Altman patterns.

C. F. Lam, C F Lam, D. Priest, 1972, Biophysical journal.

The effect of methionine on methotrexate metabolism in rat hepatocytes in monolayer culture.

D. Priest, M. Rhee, J. Galivan, 1989, Biochimica et biophysica acta.

The enhancement of the activity of 10-propargyl-5,8-dideazafolate and 5,10-dideazatetrahydrofolate by inhibitors of dihydrofolate reductase.

T B Johnson, D. Priest, T. Chou, 1989, Advances in enzyme regulation.

Serine transhydroxymethylase. Equilibrium binding of folate analogs as active site probes.

D. Priest, C. Jones, J. Hynes, 1978, Biochimica et biophysica acta.

Growth of ovarian‐carcinoma cell lines at physiological folate concentration: Effect on folate‐binding protein expression in vitro and in vivo

A. Tomassetti, S. Canevari, D. Priest, 1995, International journal of cancer.

Impact of dietary folic acid on reduced folates in mouse plasma and tissues. Relationship to dideazatetrahydrofolate sensitivity.

J. C. Schmitz, D. Priest, R. Schultz, 1994, Biochemical pharmacology.

Spatiotemporal dynamics of 53BP1 dimer recruitment to a DNA double strand break

D. Priest, Jieqiong Lou, Elizabeth Hinde, 2020, Nature Communications.

Inhibition of mammalian thymidylate synthase by 10-formyltetrahydropteroylpolyglutamate.

D. Priest, J. Whiteley, M. Rhee, 1991, Archives of biochemistry and biophysics.

Interaction of pyridoxal 5-phosphate with apo-serine hydroxymethyltransferase.

D. Priest, C. Jones, 1978, Biochimica et biophysica acta.

Nascent mutant Huntingtin exon 1 chains do not stall on ribosomes during translation but aggregates do recruit machinery involved in ribosome quality control and RNA

D. Priest, D. Cox, D. Hatters, 2020, PloS one.

Micro-patterned agarose gel devices for single-cell high-throughput microscopy of E. coli cells

N. Tanaka, D. Priest, Y. Taniguchi, 2017, Scientific Reports.

Modulation of fluorouracil antitumor activity by folic acid in a murine model system.

D. Priest, K. Raghunathan, 1999, Biochemical pharmacology.

Random pathway models and their application to steady-state enzyme kinetics.

D. Priest, J. Barton, J. Fisher, 1972, Journal of theoretical biology.

Thermodynamics and stoicheiometry of the binding of substrate analogues to uricase.

D. Priest, T. Conley, 1980, The Biochemical journal.

A novel mechanism of resistance to polyglutamatable antifolates in human CEM leukemia cells: association with the expression of an altered reduced folate carrier (RFC) with enhanced efficiency for folic acid uptake

G. Peters, Y. Assaraf, D. Priest, 1997 .