D. Alexoff

发表

Distribution Volume Ratios without Blood Sampling from Graphical Analysis of PET Data

N. Volkow, Gene-Jack Wang, J. Fowler, 1996, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

6‐[18F]Fluoro‐A‐85380, a new PET tracer for the nicotinic acetylcholine receptor: Studies in the human brain and in vivo demonstration of specific binding in white matter

N. Volkow, Gene-Jack Wang, W. Rooney, 2004, Synapse.

MR-PET image coregistration for quantitation of striatal dopamine D2 receptors.

N. Volkow, A. Levy, J. Fowler, 1996, Journal of computer assisted tomography.

Statistical 3D image reconstruction for the RatCAP PET tomograph using a physically accurate, Monte Carlo based system matrix

S. Shokouhi, D. Schlyer, P. Vaska, 2004, IEEE Symposium Conference Record Nuclear Science 2004..

Effects of modafinil on dopamine and dopamine transporters in the male human brain: clinical implications.

N. Volkow, Gene-Jack Wang, J. Fowler, 2009, JAMA.

Stimulant-induced dopamine increases are markedly blunted in active cocaine abusers

N. Volkow, D. Tomasi, Gene-Jack Wang, 2014, Molecular Psychiatry.

Brain monoamine oxidase A inhibition in cigarette smokers.

N. Volkow, Gene-Jack Wang, A. Wolf, 1996, Proceedings of the National Academy of Sciences of the United States of America.

PET imaging of thin objects: measuring the effects of positron range and partial-volume averaging in the leaf of Nicotiana tabacum.

Srilalan Krishnamoorthy, Paul Vaska, Richard Ferrieri, 2011, Nuclear medicine and biology.

Inhibition of monoamine oxidase B in the brains of smokers

N. Volkow, Gene-Jack Wang, A. Wolf, 1996, Nature.

INAUGURAL ARTICLES: Low monoamine oxidase B in peripheral organs in smokers

N. Volkow, Gene-Jack Wang, J. Fowler, 2003 .

Therapeutic doses of amphetamine or methylphenidate differentially increase synaptic and extracellular dopamine

D L Alexoff, J S Fowler, N. Volkow, 2006, Synapse.

Effects of cell phone radiofrequency signal exposure on brain glucose metabolism.

Frank Telang, Jean Logan, Dardo Tomasi, 2011, JAMA.

Unique distribution of aromatase in the human brain: In vivo studies with PET and [N‐methyl‐11C]vorozole

Frank Telang, Jean Logan, Millard Jayne, 2010, Synapse.

Strategy for the Formation of Parametric Images under Conditions of Low Injected Radioactivity Applied to PET Studies with the Irreversible Monoamine Oxidase a Tracers [11C]Clorgyline and Deuterium-Substituted [11C]Clorgyline

N. Volkow, Gene-Jack Wang, J. Fowler, 2002, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Reversible Inhibitors of Monoamine Oxidase-A (RIMAs): Robust, Reversible Inhibition of Human Brain MAO-A by CX157

Gene-Jack Wang, J. Fowler, F. Telang, 2010, Neuropsychopharmacology.

Topiramate selectively attenuates nicotine‐induced increases in monoamine release

D. Alexoff, S. Dewey, D. Marsteller, 2001, Synapse.

Reproducibility of intraperitoneal 2-deoxy-2-[18F]-fluoro-D-glucose cerebral uptake in rodents through time.

J. Fowler, D. Alexoff, S. Dewey, 2006, Nuclear medicine and biology.

Distribution and Pharmacokinetics of Methamphetamine in the Human Body: Clinical Implications

N. Volkow, Gene-Jack Wang, J. Fowler, 2010, PloS one.

Monoamine oxidase A imaging in peripheral organs in healthy human subjects

N. Volkow, Gene-Jack Wang, J. Fowler, 2003, Synapse.

Distributed Microprocessor Automation Network for Synthesizing Radiotracers Used in Positron Emission Tomography

A. Wolf, D. Alexoff, J. Russell, 1987 .

Synthesis and evaluation of inhaled [11C]butane and intravenously injected [11C]acetone as potential radiotracers for studying inhalant abuse.

D. Pareto, J. Logan, Yu-Shin Ding, 2005, Nuclear medicine and biology.

Neuropharmacological actions of cigarette smoke: brain monoamine oxidase B (MAO B) inhibition.

N. Volkow, Gene-Jack Wang, A. Wolf, 1998, Journal of addictive diseases.

A universal water target loading system with direct in-target liquid level sensing.

A. Wolf, D. Schlyer, D. Alexoff, 1992, International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes.

High Levels of Dopamine D 2 Receptors in Unaffected Members of Alcoholic Families

Rita Z. Goldstein, N. Volkow, R. Goldstein, 2006 .

Methylphenidate decreases regional cerebral blood flow in normal human subjects.

J. Lieberman, N. Volkow, J. Fowler, 1994, Life sciences.

MicroPET imaging in an animal model of anorexia nervosa

J. Fowler, D. Alexoff, S. Dewey, 2005, Synapse.

Removal of the 2.2.2 cryptand (Kryptofix 2.2.2) from 18FDG by cation exchange.

J. Fowler, D. Alexoff, S. Gatley, 1991, International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes.

Process signals to control radiotracer syntheses: Experience with the automated production of 2-deoxy-2-[18F]fluoro-D-glucose

A. Wolf, D. Alexoff, C. Shiue, 1989 .

Aromatase Imaging with [N-Methyl-11C]Vorozole PET in Healthy Men and Women

Gene-Jack Wang, J. Fowler, D. Schlyer, 2015, The Journal of Nuclear Medicine.

Positron emission tomography (PET) studies of dopaminergic/cholinergic interaction in the baboon brain

N. Volkow, J. Brodie, A. Wolf, 1990, Synapse.

Simplifications in analyzing positron emission tomography data: effects on outcome measures.

A. Kriplani, J. Logan, D. Alexoff, 2007, Nuclear medicine and biology.

Plasma input function determination for PET using a commercial laboratory robot.

A. Wolf, J. Fowler, D. Schlyer, 1995, Nuclear medicine and biology.

PET Studies of d-Methamphetamine Pharmacokinetics in Primates: Comparison with l-Methamphetamine and (−)-Cocaine

N. Volkow, H. Benveniste, J. Fowler, 2007, Journal of Nuclear Medicine.

Histone Deacetylase Inhibitor MS-275 Exhibits Poor Brain Penetration: Pharmacokinetic Studies of [ 11 C]MS-275 using Positron Emission Tomography

N. Volkow, J. Fowler, D. Alexoff, 2009 .

Investigation of SN2 [11C]cyanation for base-sensitive substrates: an improved radiosynthesis of l-[5-11C]-glutamine

J. Fowler, D. Alexoff, Tassilo Gleede, 2015, Amino Acids.

Gas‐liquid chromatographic determination of relative amounts of 2‐deoxy‐2‐flouro‐D‐glucose and 2‐deoxy‐2‐fluoro‐D‐mannose synthesized from various methods

A. Wolf, J. Fowler, D. Alexoff, 1985 .

Therapeutic doses of buspirone block D3 receptors in the living primate brain.

N. Volkow, J. Fowler, P. Skolnick, 2014, The international journal of neuropsychopharmacology.

Slow recovery of human brain MAO B after L‐Deprenyl (Selegeline) withdrawal

N. Volkow, C. Patlak, Gene-Jack Wang, 1994, Synapse.

of Human Brain MA 0 B After L-Deprenyl ( Selegeline ) Withdrawal

N. Volkow, Gene-Jack Wang, A. Wolf, 2004 .

Histone Deacetylase Inhibitor MS-275 Exhibits Poor Brain Penetration: Pharmacokinetic Studies of [11C]MS-275 using Positron Emission Tomography

N. Volkow, J. Fowler, D. Alexoff, 2010 .

Evaluation of [(11)C]metergoline as a PET radiotracer for 5HTR in nonhuman primates.

D. Alexoff, C. Shea, J. Hooker, 2010, Bioorganic & medicinal chemistry.

Selective reduction of radiotracer trapping by deuterium substitution: comparison of carbon-11-L-deprenyl and carbon-11-deprenyl-D2 for MAO B mapping.

N. Volkow, C. Patlak, Gene-Jack Wang, 1995, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Total cyanide mass measurement with micro-ion selective electrode for determination of specific activity of carbon-11 cyanide.

J. Fowler, D. Alexoff, C. Shea, 2015, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Histone deacetylase inhibitor, MS-275, exhibits poor brain penetration: PK studies of [C]MS-275 using Positron Emission Tomography.

N. Volkow, J. Fowler, D. Alexoff, 2010, ACS chemical neuroscience.

Synthesis of l-[4-11 C]Asparagine by Ring-Opening Nucleophilic 11 C-Cyanation Reaction of a Chiral Cyclic Sulfamidate Precursor.

J. Fowler, D. Alexoff, Tassilo Gleede, 2018, Chemistry.

In Vivo Imaging of Brain Aromatase in Female Baboons: [11C]Vorozole Kinetics and Effect of the Menstrual Cycle

J. Fowler, D. Pareto, J. Logan, 2013, Molecular imaging.

Reinvestigation of the synthesis and evaluation of [N-methyl-(11)C]vorozole, a radiotracer targeting cytochrome P450 aromatase.

J. Fowler, A. Biegon, D. Alexoff, 2009, Nuclear medicine and biology.

A mild, rapid synthesis of freebase [11C]nicotine from [11C]methyl triflate.

J. Fowler, D. Alexoff, Sung Won Kim, 2016, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Dynamic Precision Phenotyping Reveals Mechanism of Crop Tolerance to Root Herbivory[OPEN]

J. Fowler, D. Alexoff, M. Erb, 2016, Plant Physiology.

Dynamic Precision Phenotyping Reveals Mechanism of Crop Tolerance to 1 Root Herbivory 2 3

D. Alexoff, M. Erb, C. Robert, 2016 .

Selective, irreversible in vivo binding of [11C]clorgyline and [11C]-L-deprenyl in mice: potential for measurement of functional monoamine oxidase activity in brain using positron emission tomography.

J S Fowler, R R MacGregor, C. D. Arnett, 1985, Biochemical pharmacology.

Imaging dopamine release with Positron Emission Tomography (PET) and 11C-raclopride in freely moving animals

Dianne E. Lee, Wynne K. Schiffer, David L. Alexoff, 2008, NeuroImage.

Serial microPET measures of the metabolic reaction to a microdialysis probe implant

Anat Biegon, Wynne K. Schiffer, Martine M. Mirrione, 2006, Journal of Neuroscience Methods.

Effects of low-field magnetic stimulation on brain glucose metabolism

Nora D. Volkow, Frank Telang, Jean Logan, 2009, NeuroImage.

Long‐term stability of neurotransmitter activity investigated with 11C‐raclopride PET

J S Fowler, J D Brodie, N. Volkow, 1998, Synapse.

An efficient and practical synthesis of [2-(11)C]indole via superfast nucleophilic [(11)C]cyanation and RANEY® Nickel catalyzed reductive cyclization.

J. Fowler, D. Alexoff, J. Hooker, 2015, Organic & biomolecular chemistry.

Evaluation of a new norepinephrine transporter PET ligand in baboons, both in brain and peripheral organs

Yu-Shin Ding, Jean Logan, Payton King, 2003, Synapse.

Low dopamine striatal D2 receptors are associated with prefrontal metabolism in obese subjects: Possible contributing factors

Yu-Shin Ding, Nora D. Volkow, Panayotis K. Thanos, 2008, NeuroImage.

Caffeine increases striatal dopamine D2/D3 receptor availability in the human brain

N. Volkow, D. Tomasi, P. Thanos, 2015, Translational Psychiatry.

Ion chromatographic analysis of high specific activity 18FDG preparations and detection of the chemical impurity 2-deoxy-2-chloro-D-glucose.

D L Alexoff, J S Fowler, A. Wolf, 1992, International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes.

High levels of dopamine D2 receptors in unaffected members of alcoholic families: possible protective factors.

Frank Telang, Jean Logan, Rita Z. Goldstein, 2006, Archives of general psychiatry.

Synthesis and positron emission tomography studies of carbon-11-labeled imatinib (Gleevec).

J. Fowler, Yu-Shin Ding, D. Alexoff, 2007, Nuclear medicine and biology.

Fast uptake and long-lasting binding of methamphetamine in the human brain: Comparison with cocaine

Nora D. Volkow, Gene-Jack Wang, Frank Telang, 2008, NeuroImage.

Reproducibility of 11C-raclopride binding in the rat brain measured with the microPET R4: effects of scatter correction and tracer specific activity.

Jean Logan, Paul Vaska, Nora D Volkow, 2003, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

In vivo comparative imaging of dopamine D2 knockout and wild-type mice with (11)C-raclopride and microPET.

Jing-Huei Lee, Jean Logan, Paul Vaska, 2002, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Carbon-11 radiolabeling of iron-oxide nanoparticles for dual-modality PET/MR imaging.

Wei Wang, Sung Won Kim, David Alexoff, 2013, Nanoscale.

In vivo quantitative imaging of photoassimilate transport dynamics and allocation in large plants using a commercial positron emission tomography (PET) scanner

D. Alexoff, B. Babst, R. Ferrieri, 2015, BMC Plant Biology.

Toluene inhalation produces regionally specific changes in extracellular dopamine.

D. Alexoff, S. Dewey, R. Ferrieri, 2002, Drug and alcohol dependence.

Modular automation in PET tracer manufacturing: application of an autosynthesizer to the production of 2-deoxy-2-[18F]fluoro-D-glucose.

D L Alexoff, J A Russell, C Y Shiue, 1986, International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes.

Automation for the Synthesis and Application of PET Radiopharmaceuticals

David Alexoff, D. Alexoff, 2005 .

Recovery of [18F]fluoride from [18O]water in an electrochemical cell.

A. Wolf, D. Schlyer, D. Alexoff, 1989, International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes.

Radiosynthesis of 3-indolyl[1-¹¹C]acetic acid for phyto-PET-imaging: an improved production procedure and formulation method.

J. Fowler, D. Alexoff, B. Babst, 2014, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

A novel approach for imaging brain–behavior relationships in mice reveals unexpected metabolic patterns during seizures in the absence of tissue plasminogen activator

Joanna S. Fowler, Wynne K. Schiffer, Martine M. Mirrione, 2007, NeuroImage.

Pharmacokinetics and in vivo specificity of [LLC]dl‐threo‐methylphenidate for the presynaptic dopaminergic neuron

J S Fowler, N. Volkow, A. Wolf, 1994, Synapse.

Decreased dopamine brain reactivity in marijuana abusers is associated with negative emotionality and addiction severity

Frank Telang, Jean Logan, Dardo Tomasi, 2014, Proceedings of the National Academy of Sciences.

Separating long-lived metal ions from 18F during H218O recovery

D. Schlyer, D. Alexoff, M. Schueller, 2007 .

Cocaine abusers show a blunted response to alcohol intoxication in limbic brain regions.

J S Fowler, N. Volkow, P. Thanos, 2000, Life sciences.

Acute alcohol intoxication decreases glucose metabolism but increases acetate uptake in the human brain

Nora D. Volkow, Frank Telang, Jean Logan, 2013, NeuroImage.

Comparison of monoamine oxidase a in peripheral organs in nonsmokers and smokers.

N. Volkow, Gene-Jack Wang, J. Fowler, 2005, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Pet studies of cocaine inhibition of myocardial norepinephrine uptake

N. Volkow, A. Wolf, J. Fowler, 1994, Synapse.

Comparison of the binding of the irreversible monoamine oxidase tracers, [(11)C]clorgyline and [(11)C]l-deprenyl in brain and peripheral organs in humans.

Yu-Shin Ding, Frank Telang, Jean Logan, 2004, Nuclear medicine and biology.

Non‐MAO A binding of clorgyline in white matter in human brain

J. Fowler, D. Schlyer, J. Logan, 2001, Journal of neurochemistry.

Synthesis and positron emission tomography studies of C-11-labeled isotopomers and metabolites of GTS-21, a partial alpha7 nicotinic cholinergic agonist drug.

Vinal D. Patel, J. Fowler, J. Logan, 2007, Nuclear medicine and biology.

Knowledge-Based Automated Radiopharmaceutical Manufacturing for Positron Emission Tomography

D. L. Alexoff, D. Alexoff, 1991 .

Monoamine oxidase B (MAO B) inhibitor therapy in Parkinson's disease

N. Volkow, A. Wolf, J. Fowler, 1993, Neurology.

Implications Transporters in the Male Human Brain : Clinical Effects of Modafinil on Dopamine and Dopamine

N. Volkow, Gene-Jack Wang, J. Fowler, 2009 .

Imaging the norepinephrine transporter in humans with (S,S)-[11C]O-methyl reboxetine and PET: problems and progress.

N. Volkow, Gene-Jack Wang, J. Fowler, 2007, Nuclear medicine and biology.

Positive Emotionality is Associated with Baseline Metabolism in Orbitofrontal Cortex and in Regions of the Default Network

Nora D. Volkow, Frank Telang, Jean Logan, 2011, Molecular Psychiatry.

Acute Handling Stress Modulates Methylphenidate-induced Catecholamine Overflow in the Medial Prefrontal Cortex

N. Volkow, D. Alexoff, P. Molina, 2002, Neuropsychopharmacology.

PET imaging of monoamine oxidase B in peripheral organs in humans.

N. Volkow, Gene-Jack Wang, J. Fowler, 2002, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Reproducibility of repeated measures of carbon-11-raclopride binding in the human brain.

J S Fowler, N. Volkow, Gene-Jack Wang, 1993, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.

Development of a simultaneous PET/microdialysis method to identify the optimal dose of 11C-raclopride for small animal imaging

Jean Logan, Wynne K. Schiffer, David L. Alexoff, 2005, Journal of Neuroscience Methods.

Comparison of the pharmacokinetics of different analogs of 11C-labeled TZTP for imaging muscarinic M2 receptors with PET.

J. Fowler, J. Logan, Yu-Shin Ding, 2008, Nuclear medicine and biology.

Remote processing, delivery and injection of H2[15O] produced from a N2/H2 gas target using a simple and compact apparatus.

A. Wolf, D. Schlyer, D. Alexoff, 1994, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

Investigation of SN2 [11C]cyanation for base-sensitive substrates: an improved radiosynthesis of l-[5-11C]-glutamine

J. Fowler, D. Alexoff, Tassilo Gleede, 2015, Amino Acids.

Tetraethylene glycol promoted two-step, one-pot rapid synthesis of indole-3-[1-11C]acetic acid

J. Fowler, D. Alexoff, Sojeong Lee, 2015 .

Evidence that Formulations of the Selective MAO-B Inhibitor, Selegiline, which Bypass First-Pass Metabolism, also Inhibit MAO-A in the Human Brain

N. Volkow, Gene-Jack Wang, S. Fahn, 2014, Neuropsychopharmacology.

Gamma Vinyl-GABA Differentially Modulates NMDA Antagonist-Induced Increases in Mesocortical Versus Mesolimbic DA Transmission

J. Brodie, D. Alexoff, S. Dewey, 2001, Neuropsychopharmacology.

Direct analysis of Kryptofix 2.2.2 in 18FDG by gas chromatography using a nitrogen-selective detector.

D L Alexoff, J S Fowler, A. Wolf, 1993, Nuclear medicine and biology.

The design and performance of a portable handheld (11)CO2 delivery system.

J. Fowler, D. Schlyer, D. Alexoff, 2014, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

GABAergic attenuation of cocaine‐induced dopamine release and locomotor activity

N. Volkow, J. Brodie, J. Fowler, 1997, Synapse.

The effects of inhaled acetone on place conditioning in adolescent rats

D. Alexoff, S. Dewey, Jennifer Pai, 2008, Pharmacology Biochemistry and Behavior.

Imaging dopamine receptors in the rat striatum with the MicroPET R4: kinetic analysis of [11C]raclopride binding using graphical methods.

Jean Logan, Paul Vaska, David L Alexoff, 2004, Methods in enzymology.

Quantitative imaging with the micro-PET small-animal PET tomograph.

Paul Vaska, Daniel J Rubins, David L Alexoff, 2006, International review of neurobiology.

Relationship of estrogen synthesis capacity in the brain with obesity and self-control in men and women

N. Alia-Klein, Gene-Jack Wang, J. Fowler, 2020, Proceedings of the National Academy of Sciences.

[(11)C]PR04.MZ, a promising DAT ligand for low concentration imaging: Synthesis, efficient (11)C-O-methylation and initial small animal PET studies.

J. Fowler, D. Alexoff, F. Rösch, 2009, Bioorganic & medicinal chemistry letters.

Metabolic correlates of toluene abuse: decline and recovery of function in adolescent animals

Jonathan D. Brodie, Wynne K. Schiffer, David L. Alexoff, 2006, Psychopharmacology.

A Strategy for Removing the Bias in the Graphical Analysis Method

D L Alexoff, J S Fowler, N. Volkow, 2001, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Serotonergic modulation of striatal dopamine measured with positron emission tomography (PET) and in vivo microdialysis

J D Brodie, Gwenn S. Smith, J. Brodie, 1995, The Journal of neuroscience : the official journal of the Society for Neuroscience.

Separation of [18F]fluoride from [18O]water using anion exchange resin.

A. Wolf, D. Schlyer, D. Alexoff, 1990, International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes.

Effect of vehicle on brain uptake of [11C]toluene.

J. Logan, D. Alexoff, S. Dewey, 2002, Nuclear medicine and biology.

In vivo quantitative imaging of photoassimilate transport dynamics and allocation in large plants using a commercial positron emission tomography (PET) scanner

D. Alexoff, B. Babst, R. Ferrieri, 2015, BMC Plant Biology.

Therapeutic doses of buspirone block D3 receptors in the living primate brain.

N. Volkow, J. Fowler, P. Skolnick, 2014, The international journal of neuropsychopharmacology.

The Use of Alternative Forms of Graphical Analysis to Balance Bias and Precision in PET Images

Jean Logan, David Alexoff, Joanna S Fowler, 2010, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.