H. Mizukami

发表

Simultaneous visualization of extrinsic and intrinsic axon collaterals in Golgi-like detail for mouse corticothalamic and corticocortical cells: a double viral infection method

D. Watanabe, T. Yamamori, A. Watakabe, 2014, Front. Neural Circuits.

Glial Dysfunction in the Mouse Habenula Causes Depressive-Like Behaviors and Sleep Disturbance

Y. Isomura, H. Mizukami, K. Ozawa, 2014, The Journal of Neuroscience.

Long-Term Two-Photon Calcium Imaging of Neuronal Populations with Subcellular Resolution in Adult Non-human Primates.

Hiroshi Kawasaki, Akiya Watakabe, Osamu Sadakane, 2015, Cell reports.

Title Long-Term Two-Photon Calcium Imaging of Neuronal Populations with Subcellular Resolution in Adult Non-human Primates

Shin-Ichiro Terada, M. Matsuzaki, T. Yamamori, 2018 .

Distinct roles for primate caudate dopamine D1 and D2 receptors in visual discrimination learning revealed using shRNA knockdown

C. Yokoyama, H. Onoe, T. Yamamori, 2016, Scientific Reports.

Sustained transgene expression by human cord blood derived CD34+ cells transduced with simian immunodeficiency virus agmTYO1‐based vectors carrying the human coagulation factor VIII gene in NOD/SCID mice

A. Ishiwata, S. Madoiwa, J. Mimuro, 2004, The journal of gene medicine.

Nanosilica-induced placental inflammation and pregnancy complications: Different roles of the inflammasome components NLRP3 and ASC

T. Noda, H. Mizukami, K. Ozawa, 2015, Nanotoxicology.

Interleukin-10 expression induced by adeno-associated virus vector suppresses proteinuria in Zucker obese rats

H. Mizukami, K. Ozawa, M. Urabe, 2012, Gene Therapy.

New approaches to gene and cell therapy for hemophilia

T. Ohmori, Y. Sakata, H. Mizukami, 2015, Journal of thrombosis and haemostasis : JTH.

Adeno-Associated Virus as an Effective Malaria Booster Vaccine Following Adenovirus Priming

E. Takashima, T. Tsuboi, H. Mizukami, 2019, Front. Immunol..

Adeno-associated virus 2 co-receptors?

H. Mizukami, J. Qiu, K. Brown, 1999, Nature Medicine.

Axonal Projections from Middle Temporal Area to the Pulvinar in the Common Marmoset

Toshiki Tani, W. Suzuki, T. Yamamori, 2020, Neuroscience.

Successful Gene Transfer Using Adeno-Associated Virus Vectors into the Kidney: Comparison among Adeno-Associated Virus Serotype 1–5 Vectors in vitro and in vivo

Y. Asano, H. Mizukami, K. Ozawa, 2004, Nephron Experimental Nephrology.

The prevalence of neutralizing antibodies against adeno‐associated virus capsids is reduced in young Japanese individuals

T. Ohmori, S. Madoiwa, J. Mimuro, 2014, Journal of medical virology.

Minimizing the inhibitory effect of neutralizing antibody for efficient gene expression in the liver with adeno-associated virus 8 vectors.

T. Ohmori, A. Ishiwata, S. Madoiwa, 2013, Molecular therapy : the journal of the American Society of Gene Therapy.

Adeno-associated virus (AAV)-3-based vectors transduce haematopoietic cells not susceptible to transduction with AAV-2-based vectors.

H. Mizukami, J. Qiu, S. Muramatsu, 2000, The Journal of general virology.

Adenoassociated Virus–Mediated Prostacyclin Synthase Expression Prevents Pulmonary Arterial Hypertension in Rats

U. Ikeda, K. Shimada, J. Mimuro, 2007, Hypertension.

Survivin overexpression via adeno‐associated virus vector Rh10 ameliorates ischemic damage after middle cerebral artery occlusion in rats

K. Kawai, H. Mizukami, M. Urabe, 2018, The European journal of neuroscience.

IL-21 is not necessary for anti-lymphoma effects of T cells expressing second-generation CD19-specific chimeric antigen receptors in a xenograft mouse model.

H. Mizukami, K. Ozawa, Masataka Nakamura, 2013 .

Overexpression of PTEN increases sensitivity to SN-38, an active metabolite of the topoisomerase I inhibitor irinotecan, in ovarian cancer cells.

Y. Saga, Mitsuaki Suzuki, H. Mizukami, 2002, Clinical cancer research : an official journal of the American Association for Cancer Research.

Gene Therapy for Diabetic Retinopathy in Animal Models and Humans

H. Mizukami, K. Ozawa, M. Urabe, 2011 .

A sensitive and reproducible cell-based assay via secNanoLuc to detect neutralizing antibody against adeno-associated virus vector capsid

M. Hayakawa, T. Ohmori, Y. Kashiwakura, 2021, Molecular therapy. Methods & clinical development.

Comprehensive Metabolomic Analysis of IDH1R132H Clinical Glioma Samples Reveals Suppression of β-oxidation Due to Carnitine Deficiency

K. Kawai, E. Sakashita, H. Endo, 2019, Scientific Reports.

AAV6-Mediated IL-10 Expression in the Lung Ameliorates Bleomycin-Induced Pulmonary Fibrosis in Mice.

Y. Saga, H. Mizukami, M. Urabe, 2018, Human gene therapy.

Efficient Establishment of Pig Embryonic Fibroblast Cell Lines with Conditional Expression of the Simian Vacuolating Virus 40 Large T Fragment

T. Uchida, H. Mizukami, Hisao Ito, 2012, Bioscience, biotechnology, and biochemistry.

Adeno-associated virus vector-mediated interleukin-10 gene transfer inhibits atherosclerosis in apolipoprotein E-deficient mice

U. Ikeda, K. Shimada, H. Mizukami, 2004, Gene Therapy.

Reciprocal upregulation of Notch signaling molecules in hematopoietic progenitor and mesenchymal stromal cells

H. Mizukami, K. Ozawa, T. Nagai, 2011, Journal of stem cells & regenerative medicine.

Prophylaxis and Treatment of Alzheimer's Disease by Delivery of an Adeno-Associated Virus Encoding a Monoclonal Antibody Targeting the Amyloid Beta Protein

H. Mizukami, K. Ozawa, K. Okuda, 2013, PloS one.

Novel anti-tumor mechanism of galanin receptor type 2 in head and neck squamous cell carcinoma cells

T. Carey, H. Mizukami, K. Ozawa, 2013, Cancer science.

Suppression of lymph node and lung metastases of endometrial cancer by muscle‐mediated expression of soluble vascular endothelial growth factor receptor‐3

Y. Saga, Mitsuaki Suzuki, H. Mizukami, 2013, Cancer science.

Protection against aminoglycoside-induced ototoxicity by regulated AAV vector-mediated GDNF gene transfer into the cochlea.

H. Mizukami, K. Ozawa, K. Sheykholeslami, 2008, Molecular therapy : the journal of the American Society of Gene Therapy.

AAV-mediated VEGF gene transfer into skeletal muscle stimulates angiogenesis and improves blood flow in a rat hindlimb ischemia model.

U. Ikeda, K. Shimada, M. Shibuya, 2002, Cardiovascular research.

Oxytocin receptor in the hypothalamus is sufficient to rescue normal thermoregulatory function in male oxytocin receptor knockout mice.

S. Roh, H. Mizukami, K. Ozawa, 2013, Endocrinology.

Generation of Adeno-Associated Virus Vector Enabling Functional Expression of Oxytocin Receptor and Fluorescence Marker Genes Using the Human eIF4G Internal Ribosome Entry Site Element

H. Mizukami, K. Ozawa, K. Nishimori, 2009, Bioscience, biotechnology, and biochemistry.

Adipose tissue as a novel target for in vivo gene transfer by adeno-associated viral vectors.

J. Mimuro, Y. Sakata, H. Mizukami, 2006, Human gene therapy.

Adeno-associated virus vectors for gene transfer to the brain.

W. Lijun, H. Mizukami, K. Ozawa, 2002, Methods.

Adeno‐associated virus vector‐mediated systemic interleukin‐10 expression ameliorates hypertensive organ damage in Dahl salt‐sensitive rats

U. Ikeda, K. Shimada, H. Mizukami, 2008, The journal of gene medicine.

Overexpression of thymidylate synthase mediates desensitization for 5‐fluorouracil of tumor cells

Y. Saga, M. Fukushima, Mitsuaki Suzuki, 2003, International journal of cancer.

Enhanced Expression of Thymidylate Synthase Mediates Resistance of Uterine Cervical Cancer Cells to Radiation

Y. Saga, M. Fukushima, Mitsuaki Suzuki, 2002, Oncology.

The hepatocyte growth factor antagonist NK4 inhibits indoleamine-2,3-dioxygenase expression via the c-Met-phosphatidylinositol 3-kinase-AKT signaling pathway

Y. Saga, H. Mizukami, Toshikazu Nakamura, 2016, International journal of oncology.

Adeno-associated Virus Vector-mediated Interleukin-10 Induction Prevents Vascular Inflammation in a Murine Model of Kawasaki Disease

H. Mizukami, N. Ohno, Ryouta Kamata, 2018, Scientific Reports.

NLRP3 Deficiency Reduces Macrophage Interleukin-10 Production and Enhances the Susceptibility to Doxorubicin-induced Cardiotoxicity

N. Hasebe, H. Mizukami, Masafumi Takahashi, 2016, Scientific Reports.

In vivo expansion of transduced murine hematopoietic cells with a selective amplifier gene

H. Mizukami, K. Ozawa, Y. Hanazono, 2003, The journal of gene medicine.

Interleukin-10 Expression Mediated by an Adeno-Associated Virus Vector Prevents Monocrotaline-Induced Pulmonary Arterial Hypertension in Rats

U. Ikeda, K. Shimada, H. Mizukami, 2007, Circulation research.

Repair of articular cartilage defect by intraarticular administration of basic fibroblast growth factor gene, using adeno-associated virus vector.

H. Mizukami, K. Ozawa, Tomoyuki Saito, 2005, Human gene therapy.

Repair of articular cartilage defect by autologous transplantation of basic fibroblast growth factor gene-transduced chondrocytes with adeno-associated virus vector.

H. Mizukami, K. Ozawa, Tomoyuki Saito, 2005, Arthritis and rheumatism.

Triple transduction with adeno-associated virus vectors expressing tyrosine hydroxylase, aromatic-L-amino-acid decarboxylase, and GTP cyclohydrolase I for gene therapy of Parkinson's disease.

H. Mizukami, K. Ozawa, M. Urabe, 2000, Human gene therapy.

Highly regulated expression of adeno-associated virus large Rep proteins in stable 293 cell lines using the Cre/loxP switching system.

H. Mizukami, K. Ozawa, M. Urabe, 1999, The Journal of general virology.

Oral administration of recombinant adeno-associated virus elicits human immunodeficiency virus-specific immune responses.

H. Mizukami, K. Ozawa, K. Hamajima, 2002, Human gene therapy.

Liver-Directed AAV8 Booster Vaccine Expressing Plasmodium falciparum Antigen Following Adenovirus Vaccine Priming Elicits Sterile Protection in a Murine Model

H. Mizukami, D. Yamamoto, M. Iyori, 2021, Frontiers in Immunology.

Vasopressinergic control of stress-related behavior: studies in Brattleboro rats

S. Weger, R. Heilbronn, H. Mizukami, 2016, Stress.

Mutant macaque factor IX T262A: a tool for hemophilia B gene therapy studies in macaques.

T. Ohmori, Y. Kashiwakura, A. Ishiwata, 2010, Thrombosis research.

Expansion of genetically corrected neutrophils in chronic granulomatous disease mice by cotransferring a therapeutic gene and a selective amplifier gene

H. Mizukami, K. Ozawa, H. Moriwaki, 2004, Gene Therapy.

Adeno-associated virus type 2 binds to a 150-kilodalton cell membrane glycoprotein.

N. Young, H. Mizukami, K. Brown, 1996, Virology.

Suicide gene therapy using AAV-HSVtk/ganciclovir in combination with irradiation results in regression of human head and neck cancer xenografts in nude mice

H. Mizukami, K. Ozawa, Y. Hanazono, 2003, Gene Therapy.

AAV Vector-Mediated Liver Gene Therapy and Its Implementation for Hemophilia

T. Ohmori, J. Mimuro, Y. Sakata, 2016 .

Complete restoration of phenylalanine oxidation in phenylketonuria mouse by a self‐complementary adeno‐associated virus vector

H. Yoshikawa, H. Mizukami, K. Ozawa, 2011, The journal of gene medicine.

Development and characterization of an antisense-mediated prepackaging cell line for adeno-associated virus vector production.

H. Mizukami, K. Ozawa, Y. Hanazono, 2001, Biochemical and biophysical research communications.

Targeted Integration of Foreign DNA Into a Defined Locus on Chromosome 19 in K562 Cells Using AAV-Derived Components

H. Mizukami, K. Ozawa, M. Urabe, 2001, International journal of hematology.

Suppression of cell migration in ovarian cancer cells mediated by PTEN overexpression.

Y. Saga, Mitsuaki Suzuki, H. Mizukami, 2003, International journal of oncology.

A soluble CAR‐SCF fusion protein improves adenoviral vector‐mediated gene transferto c‐Kit‐positive hematopoietic cells

H. Mizuguchi, T. Hayakawa, H. Mizukami, 2003, The journal of gene medicine.

Recovery of neurogenic amines in phenylketonuria mice after liver-targeted gene therapy

H. Mizukami, K. Ozawa, M. Urabe, 2012, Neuroreport.

Manufacturing and characterization of a recombinant adeno-associated virus type 8 reference standard material.

L. Zentilin, M. Giacca, L. Tenenbaum, 2014, Human gene therapy.

Distinct patterns of gene transfer to gerbil hippocampus with recombinant adeno-associated virus type 2 and 5

H. Mizukami, K. Ozawa, Y. Hanazono, 2003, Neuroscience Letters.

Adeno-associated viral vector-mediated gene therapy of ischemia-induced neuronal death.

N. Kawai, H. Mizukami, K. Ozawa, 2002, Methods in enzymology.

Oxytocin Receptor-Expressing Neurons and Nuclei in the Regulation of Social Behaviors

H. Mizukami, K. Nishimori, S. Hidema, 2015 .

Reduction of CTLL‐2 cytotoxicity by induction of apoptosis with a Fas‐estrogen receptor chimera

H. Mizukami, K. Ozawa, Y. Hanazono, 2003, Cancer science.

The adenovirus E1A and E1B19K genes provide a helper function for transfection-based adeno-associated virus vector production.

T. Inaba, H. Mizukami, K. Ozawa, 2004, The Journal of general virology.

A Viral-Vectored Multi-Stage Malaria Vaccine Regimen With Protective and Transmission-Blocking Efficacies

H. Mizukami, S. Fukumoto, T. Emran, 2019, Front. Immunol..

Large-scale production of recombinant viruses by use of a large culture vessel with active gassing.

H. Mizukami, K. Ozawa, A. Kume, 2005, Human gene therapy.

Cell and gene therapy using mesenchymal stem cells (MSCs).

Kazuya Sato, H. Mizukami, K. Ozawa, 2008, Journal of autoimmunity.

Development of a mouse model for lymph node metastasis with endometrial cancer

Y. Saga, Mitsuaki Suzuki, H. Mizukami, 2011, Cancer science.

Retroviral vector‐producing mesenchymal stem cells for targeted suicide cancer gene therapy

H. Mizukami, K. Ozawa, M. Urabe, 2009, The journal of gene medicine.

Expression of HGF/NK4 in ovarian cancer cells suppresses intraperitoneal dissemination and extends host survival

T. Nakamura, Y. Saga, H. Mizukami, 2001, Gene Therapy.

Overexpression of a hybrid gene consisting of the amino‐terminal fragment of urokinase and carboxyl‐terminal domain of bikunin suppresses invasion and migration of human ovarian cancer cells in vitro

Y. Saga, Mitsuaki Suzuki, H. Mizukami, 2005, International journal of cancer.

Comparative analyses of adeno-associated viral vector serotypes 1, 2, 5, 8 and 9 in marmoset, mouse and macaque cerebral cortex

T. Yamamori, K. Isa, T. Isa, 2015, Neuroscience Research.

NF-κB activity regulates mesenchymal stem cell accumulation at tumor sites.

Y. Saga, H. Mizuguchi, H. Mizukami, 2013, Cancer research.

Selective growth advantage of wild-type lymphocytes in X-linked SCID recipients

K. Sugamura, H. Mizukami, K. Ozawa, 2002, Bone Marrow Transplantation.

[Utility of AAV vectors derived from novel serotypes].

H. Mizukami, K. Ozawa, 2006, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

Safety of intra-articular transplantation of lentivirally transduced mesenchymal stromal cells for haemophilic arthropathy in a non-human primate

H. Sugimoto, T. Ohmori, Y. Sakata, 2018, International Journal of Hematology.

Liver‐restricted expression of the canine factor VIII gene facilitates prevention of inhibitor formation in factor VIII‐deficient mice

T. Ohmori, Y. Kashiwakura, A. Ishiwata, 2009, The journal of gene medicine.

CRISPR/Cas9-mediated genome editing via postnatal administration of AAV vector cures haemophilia B mice

O. Nureki, S. Tominaga, T. Ohmori, 2017, Scientific Reports.

Overexpression of factor VII ameliorates bleeding diathesis of factor VIII-deficient mice with inhibitors.

T. Ohmori, Y. Kashiwakura, A. Ishiwata, 2013, Thrombosis research.

Phenotype correction of hemophilia A mice with adeno-associated virus vectors carrying the B domain-deleted canine factor VIII gene.

T. Ohmori, Y. Kashiwakura, A. Ishiwata, 2006, Thrombosis research.

Characterization of a recombinant adeno-associated virus type 2 Reference Standard Material.

Terence R Flotte, Hiroaki Mizukami, Mauro Giacca, 2010, Human gene therapy.

The decline in synaptic GluN2B and rise in inhibitory neurotransmission determine the end of a critical period

M. Sakurai, M. Mishina, H. Mizukami, 2016, Scientific Reports.

Corticospinal Tract Development and Spinal Cord Innervation Differ between Cervical and Lumbar Targets

M. Sakurai, H. Mizukami, K. Ozawa, 2015, The Journal of Neuroscience.

DNA Methylation and Methyl-Binding Proteins Control Differential Gene Expression in Distinct Cortical Areas of Macaque Monkey

T. Yamamori, T. Isa, A. Watakabe, 2013, The Journal of Neuroscience.

Gene therapy improves motor and mental function of aromatic l-amino acid decarboxylase deficiency

Takeshi Nakajima, H. Mizukami, Mitsuhiro Kato, 2019, Brain : a journal of neurology.

Downregulation of indoleamine-2,3-dioxygenase in cervical cancer cells suppresses tumor growth by promoting natural killer cell accumulation

Y. Saga, Mitsuaki Suzuki, H. Mizukami, 2012, Oncology reports.

Indoleamine-2,3-dioxygenase, an immunosuppressive enzyme that inhibits natural killer cell function, as a useful target for ovarian cancer therapy

Y. Saga, Mitsuaki Suzuki, H. Mizukami, 2011, International journal of oncology.

Soluble FLT-1 expression suppresses carcinomatous ascites in nude mice bearing ovarian cancer.

Y. Taketani, M. Shibuya, T. Tsuruo, 2002, Cancer research.

Axonal Projections From the Middle Temporal Area in the Common Marmoset

Akiya Watakabe, Taku Hayami, Tetsuo Yamamori, 2018, Frontiers in Neuroanatomy.

Selective Expansion of Transduced Cells for Hematopoietic Stem Cell Gene Therapy

H. Mizukami, Y. Hanazono, A. Kume, 2002, International journal of hematology.

Induction of Robust Immune Responses against Human Immunodeficiency Virus Is Supported by the Inherent Tropism of Adeno-Associated Virus Type 5 forDendritic Cells

H. Mizukami, K. Ozawa, M. Urabe, 2006, Journal of Virology.

Eradication of cervical cancer in vivo by an AAV vector that encodes shRNA targeting human papillomavirus type 16 E6/E7

Y. Saga, Mitsuaki Suzuki, H. Mizukami, 2018, International journal of oncology.

Persistent phenotypic correction of central diabetes insipidus using adeno-associated virus vector expressing arginine-vasopressin in Brattleboro rats.

H. Mizukami, K. Ozawa, S. Ishibashi, 2003, Molecular therapy : the journal of the American Society of Gene Therapy.

Adeno-associated virus vector-mediated production of hepatocyte growth factor attenuates liver fibrosis in mice

H. Mizukami, K. Ozawa, J. Fujimoto, 2008, Hepatology international.

Suppression of ovarian cancer by muscle‐mediated expression of soluble VEGFR‐1/Flt‐1 using adeno‐associated virus serotype 1‐derived vector

Y. Saga, Mitsuaki Suzuki, H. Mizukami, 2007, International journal of cancer.

Separate control of rep and cap expression using mutant and wild-type LoxP sequences and improved packaging system for adeno-associated virus vector production

H. Mizukami, K. Ozawa, M. Urabe, 2004, Molecular biotechnology.

Interleukin-10-mediated inhibition of angiogenesis and tumor growth in mice bearing VEGF-producing ovarian cancer.

Y. Saga, Mitsuaki Suzuki, H. Mizukami, 2003, Cancer research.

Cancer Tumor Growth in Mice Bearing VEGF-producing Ovarian Interleukin-10-mediated Inhibition of Angiogenesis and Updated Version

Y. Saga, Mitsuaki Suzuki, H. Mizukami, 2003 .

Delayed delivery of AAV-GDNF prevents nigral neurodegeneration and promotes functional recovery in a rat model of Parkinson's disease

H. Mizukami, K. Ozawa, Y. Hanazono, 2002, Gene Therapy.

Overexpression of PTEN in ovarian cancer cells suppresses i.p. dissemination and extends survival in mice

Y. Saga, Mitsuaki Suzuki, H. Mizukami, 2008, Molecular Cancer Therapeutics.

Intramuscular injection of AAV-GDNF results in sustained expression of transgenic GDNF, and its delivery to spinal motoneurons by retrograde transport

H. Mizukami, K. Ozawa, Y. Hanazono, 2003, Neuroscience Research.

Higher Transduction Efficiency of AAV5 to Neural Stem Cells and Immature Neurons in Gerbil Dentate Gyrus Compared to AAV2 and rh10.

A. Inutsuka, K. Kawai, H. Mizukami, 2021, Human gene therapy.

Gene Therapy with Virus Vectors for specific Disease of the Nervous System

H. Mizukami, K. Ozawa, Y. Hanazono, 2003 .

Adeno-associated viral vectors for Parkinson's disease.

H. Mizukami, K. Ozawa, Y. Hanazono, 2003, International review of neurobiology.

Behavioral recovery in a primate model of Parkinson's disease by triple transduction of striatal cells with adeno-associated viral vectors expressing dopamine-synthesizing enzymes.

M. Matsumura, H. Mizukami, K. Ozawa, 2002, Human gene therapy.

CRISPR/Cas9-mediated cervical cancer treatment targeting human papillomavirus E6

Y. Saga, H. Mizukami, S. Matsubara, 2018, Oncology letters.

A histone deacetylase inhibitor enhances recombinant adeno-associated virus-mediated gene expression in tumor cells.

H. Mizukami, K. Ozawa, A. Kume, 2006, Molecular therapy : the journal of the American Society of Gene Therapy.

Reversible integration of the dominant negative retinoid receptor gene for ex vivo expansion of hematopoietic stem/progenitor cells.

H. Mizukami, K. Ozawa, M. Muramatsu, 2001, Biochemical and biophysical research communications.

Cetuximab inhibits the growth of mucinous ovarian carcinoma tumor cells lacking KRAS gene mutations.

Y. Saga, Mitsuaki Suzuki, H. Mizukami, 2012, Oncology reports.

The angiogenesis regulator vasohibin-1 inhibits ovarian cancer growth and peritoneal dissemination and prolongs host survival

Y. Saga, Yoshifumi Takahashi, H. Mizukami, 2015, International journal of oncology.

Optimization of adeno-associated virus vector-mediated gene transfer to the respiratory tract

Y. Saga, Y. Sugiyama, H. Mizukami, 2017, Gene Therapy.

Gene transfer techniques using AAV vectors

H. Mizukami, 2008 .

Utility of intraperitoneal administration as a route of AAV serotype 5 vector‐mediated neonatal gene transfer

H. Yoshikawa, S. Madoiwa, J. Mimuro, 2006, The journal of gene medicine.

Specific detection of human coagulation factor IX in cynomolgus macaques

S. Madoiwa, J. Mimuro, Y. Sakata, 2004, Journal of thrombosis and haemostasis : JTH.

A novel recombinant adeno-associated virus vaccine induces a long-term humoral immune response to human immunodeficiency virus.

H. Mizukami, K. Ozawa, M. Urabe, 2001, Human gene therapy.

Utility of microminipigs for evaluating liver-mediated gene expression in the presence of neutralizing antibody against vector capsid

T. Ohmori, H. Mizukami, S. Hishikawa, 2020, Gene Therapy.

The seroprevalence of neutralizing antibodies against the adeno-associated virus capsids in Japanese hemophiliacs

M. Hayakawa, S. Ishikawa, T. Ohmori, 2022, medRxiv.

Removal of empty capsids from type 1 adeno-associated virus vector stocks by anion-exchange chromatography potentiates transgene expression.

H. Mizukami, K. Ozawa, M. Urabe, 2006, Molecular therapy : the journal of the American Society of Gene Therapy.

Scalable Generation of High-Titer Recombinant Adeno-Associated Virus Type 5 in Insect Cells

R. Kotin, H. Mizukami, K. Ozawa, 2006, Journal of Virology.

Higher primate-like direct corticomotoneuronal connections are transiently formed in a juvenile subprimate mammal

Y. Yoshimura, Takuma Mori, M. Sakurai, 2018, Scientific Reports.

Corticospinal axons make direct synaptic connections with spinal motoneurons innervating forearm muscles early during postnatal development in the rat

M. Sakurai, H. Mizukami, K. Ozawa, 2016, The Journal of physiology.

Sterile protection and transmission blockade by a multistage anti-malarial vaccine in the pre-clinical study

W. F. Gregory, A. Blagborough, N. Hori, 2022, Frontiers in Immunology.

Selective Optical Control of Synaptic Transmission in the Subcortical Visual Pathway by Activation of Viral Vector-Expressed Halorhodopsin

D. Watanabe, K. Kaneda, T. Isa, 2011, PloS one.

Specific and efficient transduction of Cochlear inner hair cells with recombinant adeno-associated virus type 3 vector.

H. Mizukami, K. Ozawa, K. Takeuchi, 2005, Molecular therapy : the journal of the American Society of Gene Therapy.

An R132H Mutation in Isocitrate Dehydrogenase 1 Enhances p21 Expression and Inhibits Phosphorylation of Retinoblastoma Protein in Glioma Cells

H. Mizukami, K. Ozawa, M. Urabe, 2013, Neurologia medico-chirurgica.

Neuroprotective Effects of Glial Cell Line-Derived Neurotrophic Factor Mediated by an Adeno-Associated Virus Vector in a Transgenic Animal Model of Amyotrophic Lateral Sclerosis

H. Mizukami, K. Ozawa, Y. Hanazono, 2002, The Journal of Neuroscience.

A Phase I Study of Aromatic L-Amino Acid Decarboxylase Gene Therapy for Parkinson's Disease.

H. Mizukami, K. Ozawa, M. Urabe, 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

Comprehensive Metabolomic Analysis of IDH1R132H Clinical Glioma Samples Reveals Suppression of β-oxidation Due to Carnitine Deficiency

K. Kawai, E. Sakashita, H. Endo, 2019, Scientific Reports.

The Tol2 transposon system mediates the genetic engineering of T-cells with CD19-specific chimeric antigen receptors for B-cell malignancies

K. Kawakami, Y. Saga, H. Mizukami, 2014, Gene Therapy.

Functional Analysis of an Inducible Promoter Driven by Activation Signals from a Chimeric Antigen Receptor

H. Mizukami, K. Ozawa, M. Urabe, 2018, Molecular therapy oncolytics.

CD19 target-engineered T-cells accumulate at tumor lesions in human B-cell lymphoma xenograft mouse models.

M. Sadelain, H. Mizukami, K. Ozawa, 2013, Biochemical and biophysical research communications.

γ-Rays enhance rAAV-mediated transgene expression and cytocidal effect of AAV-HSVtk/ganciclovir on cancer cells

H. Mizukami, K. Ozawa, M. Urabe, 2001, Cancer Gene Therapy.

Nucleotide sequencing and generation of an infectious clone of adeno-associated virus 3.

N. Young, H. Mizukami, S. Muramatsu, 1996, Virology.

Role of the Oxytocin Receptor Expressed in the Rostral Medullary Raphe in Thermoregulation During Cold Conditions

H. Mizukami, K. Ozawa, K. Nishimori, 2015, Front. Endocrinol..

Cerebrospinal fluid neprilysin is reduced in prodromal Alzheimer's disease

H. Arai, M. Higuchi, Hidetada Sasaki, 2005, Annals of neurology.

Prevention of diabetic retinopathy by intraocular soluble flt-1 gene transfer in a spontaneously diabetic rat model.

H. Mizukami, K. Ozawa, M. Kawakami, 2007, International journal of molecular medicine.

Depression-like episodes in mice harboring mtDNA deletions in paraventricular thalamus

A. Kakita, A. Takata, H. Mizukami, 2015, Molecular Psychiatry.

Presynaptic dysregulation of the paraventricular thalamic nucleus causes depression-like behavior

Shigeyoshi Fujisawa, H. Mizukami, K. Ozawa, 2019, Scientific Reports.

Presynaptic Localization of Neprilysin Contributes to Efficient Clearance of Amyloid-β Peptide in Mouse Brain

H. Mizukami, K. Ozawa, S. Muramatsu, 2004, The Journal of Neuroscience.

A phase I study of aromatic L-amino acid decarboxylase gene therapy for Parkinson's disease.

H. Mizukami, K. Ozawa, M. Urabe, 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

Systemic delivery of IL-10 by an AAV vector prevents vascular remodeling and end-organ damage in stroke-prone spontaneously hypertensive rat

U. Ikeda, H. Mizukami, K. Ozawa, 2009, Gene Therapy.

Two-photon imaging of neuronal activity in motor cortex of marmosets during upper-limb movement tasks

Akiya Watakabe, Tetsuo Yamamori, Atsushi Nambu, 2018, Nature Communications.

Direct reprogramming with Sendai virus vectors repaired infarct hearts at the chronic stage.

H. Mizukami, K. Fukuda, R. Fujita, 2021, Biochemical and biophysical research communications.

In Vivo Two-Photon Imaging of Dendritic Spines in Marmoset Neocortex1,2,3

Tadashi Isa, Hiroshi Kawasaki, Akiya Watakabe, 2015, eNeuro.

Vasohibin‐1 expression inhibits advancement of ovarian cancer producing various angiogenic factors

Y. Saga, Yoshifumi Takahashi, H. Mizukami, 2016, Cancer science.

CRISPR/Cas9-mediated genome editing via postnatal administration of AAV vector cures haemophilia B mice

O. Nureki, S. Tominaga, T. Ohmori, 2017, Scientific Reports.

Long-term correction of hyperphenylalaninemia by AAV-mediated gene transfer leads to behavioral recovery in phenylketonuria mice

H. Mizukami, K. Ozawa, Y. Matsubara, 2004, Gene Therapy.

Fear-enhancing effects of septal oxytocin receptors

N. Tronson, H. Mizukami, K. Nishimori, 2013, Nature Neuroscience.

The cardiac pacemaker-specific channel Hcn4 is a direct transcriptional target of MEF2.

Hideki Uosaki, M. Takano, H. Mizukami, 2009, Cardiovascular research.

Hematopoietic stem cell gene therapy: a current overview.

H. Mizukami, K. Ozawa, Y. Hanazono, 1999, International journal of hematology.

Tendon Healing In Vitro: Adeno-Associated Virus-2 Effectively Transduces Intrasynovial Tenocytes with Persistent Expression of the Transgene, but Other Serotypes Do Not

H. Ushijima, H. Mizukami, K. Ozawa, 2007, Plastic and reconstructive surgery.

Differential innervation within a transverse plane of spinal gray matter by sensorimotor cortices, with special reference to the somatosensory cortices

M. Sakurai, H. Mizukami, K. Ozawa, 2019, The Journal of comparative neurology.

Targeting oxytocin receptor (Oxtr)-expressing neurons in the lateral septum to restore social novelty in autism spectrum disorder mouse models

H. Bito, H. Mizukami, K. Shimomura, 2020, Scientific Reports.

Adeno-associated Virus Vector-mediated Interleukin-10 Induction Prevents Vascular Inflammation in a Murine Model of Kawasaki Disease

H. Mizukami, N. Ohno, Ryouta Kamata, 2018, Scientific Reports.

Lymphold reconstitution in X-linked severe combined immunodeficient mice by retrovirus-mediated gene transfer

K. Sugamura, H. Mizukami, K. Ozawa, 2002 .

Calcium Transient Dynamics of Neural Ensembles in the Primary Motor Cortex of Naturally Behaving Monkeys.

Junichi Ushiba, Hideyuki Okano, Akihiro Yamanaka, 2018, Cell reports.

Annexin A5 Involvement in Bone Overgrowth at the Enthesis

Y. Ezura, H. Mizukami, T. Yamashita, 2018, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

A convenient enzyme-linked immunosorbent assay for rapid screening of anti-adeno-associated virus neutralizing antibodies

H. Mizukami, K. Ozawa, S. Muramatsu, 2009, Annals of clinical biochemistry.

Parcellation of the murine cortical hindlimb area is demonstrated by its subcortical connectivity and cytoarchitecture

M. Sakurai, Toshihiro Hayashi, H. Mizukami, 2022, The Journal of comparative neurology.

PAT—Probabilistic Axon Tracking for Densely Labeled Neurons in Large 3-D Micrographs

Shin Ishii, Ken Nakae, Hideyuki Okano, 2019, IEEE Transactions on Medical Imaging.

Arm movements induced by noninvasive optogenetic stimulation of the motor cortex in the common marmoset

Teppei Ebina, Akiya Watakabe, Tetsuo Yamamori, 2019, Proceedings of the National Academy of Sciences.

Mutant macaque factor IX T262A: a tool for hemophilia B gene therapy studies in macaques.

T. Ohmori, Y. Kashiwakura, S. Madoiwa, 2010, Thrombosis Research.

Therapeutic strategy for Fabry disease by intravenous administration of adeno‐associated virus 2 or 9 in α‐galactosidase A‐deficient mice

H. Mizukami, K. Ohba, Y. Sakiyama, 2023, The journal of gene medicine.

Generation of Oxtr cDNAHA‐Ires‐Cre Mice for Gene Expression in an Oxytocin Receptor Specific Manner

H. Mizukami, K. Nishimori, S. Hidema, 2016, Journal of cellular biochemistry.

Efficient transduction of adeno-associated virus vectors into gerbil hippocampus with an appropriate combination of viral capsids and promoters

K. Kawai, H. Mizukami, M. Urabe, 2018, Neuroscience Letters.

Characterization of a recombinant adeno-associated virus type 2 Reference Standard Material.

L. Zentilin, M. Giacca, T. Conlon, 2010, Human gene therapy.

Cetuximab inhibits the growth of mucinous ovarian carcinoma tumor cells lacking KRAS gene mutations.

Y. Saga, Mitsuaki Suzuki, H. Mizukami, 2012, Oncology reports.

A convenient enzyme-linked immunosorbent assay for rapid screening of anti-adeno-associated virus neutralizing antibodies

H. Mizukami, K. Ozawa, S. Muramatsu, 2009, Annals of clinical biochemistry.

Adeno-associated virus vector system controlling capsid expression improves viral quantity and quality.

H. Mizukami, K. Ozawa, T. Enoki, 2023, iScience.