D. Doherty

发表

Defining the outcome of immunosuppression withdrawal after liver transplantation

B. Portmann, Roger Williams, J. Devlin, 1998, Hepatology.

Immune Dysregulation in Children With Down Syndrome

D. Doherty, E. Molloy, D. Huggard, 2020, Frontiers in Pediatrics.

Altered endotoxin responsiveness in healthy children with Down syndrome

D. Doherty, E. Molloy, T. R. Leahy, 2018, BMC Immunology.

Pretransplantation CD56+ innate lymphocyte populations associated with severity of hepatitis C virus recurrence

D. Doherty, C. O’Farrelly, H. Rosen, 2008, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

Innate Immune Mechanisms in the Liver

D. Doherty, C. O’Farrelly, 2007 .

Core Concepts in Immunology

D. Doherty, C. O’Farrelly, 2014 .

The role of the liver in the migration of parasites of global significance

D. Doherty, J. Carolan, C. Holland, 2019, Parasites & Vectors.

Characterization of NKR+ T-cell subsets in human bone marrow: implications for immunosurveillance of neoplasia.

D. Doherty, C. O’Farrelly, M. Lawler, 2005, Clinical immunology.

Amino acid substitutions at position 38 of the DRβ polypeptide confer susceptibility to and protection from primary sclerosing cholangitis

R. Vaughan, K. Welsh, D. Doherty, 1992 .

Human leukocyte antigen A1‐B8‐DR3‐DQ2‐DPB1*0401 extended haplotype in autoimmune hepatitis

G. Mieli-Vergani, D. Doherty, P. Donaldson, 1993, Hepatology.

Activation and Regulation of B Cell Responses by Invariant Natural Killer T Cells

D. Doherty, A. Melo, A. Moreno-Olivera, 2018, Front. Immunol..

Glucagon-like peptide-1 (GLP-1) and the regulation of human invariant natural killer T cells: lessons from obesity, diabetes and psoriasis

D. Doherty, L. Lynch, P. Moynagh, 2011, Diabetologia.

IL-23R is Epigenetically Regulated and Modulated by Chemotherapy in Non-Small Cell Lung Cancer

K. O'Byrne, D. Doherty, S. Gray, 2013, Front. Oncol..

CD1d expression and invariant natural killer T-cell numbers are reduced in patients with upper gastrointestinal cancers and are further impaired by commonly used chemotherapies

J. Reynolds, D. Doherty, A. Melo, 2020, Cancer Immunology, Immunotherapy.

Cigarette smoke alters the invariant natural killer T cell function and may inhibit anti-tumor responses.

D. Doherty, L. Lynch, D. O'Shea, 2011, Clinical immunology.

Hepatic expression of IL-15 mRNA is associated with liver graft acceptance.

B. Portmann, N. Heaton, D. Doherty, 2003, Transplant immunology.

Resident human hepatic lymphocytes are phenotypically different from circulating lymphocytes.

D. Doherty, G. Mcentee, O. Traynor, 1998, Journal of hepatology.

Innate and adaptive lymphoid cells in the human liver

D. Doherty, C. O’Farrelly, 2000, Immunological reviews.

Dysregulated T helper type 1 (Th1) and Th17 responses in elderly hospitalised patients with infection and sepsis

J. D. Coakley, R. McManus, D. Doherty, 2019, PloS one.

Increased frequencies circulating of IFN γ producing Vδ1+ and Vδ2+ gamma/delta T cells in patients with asymptomatic persistent hepatitis B virus infection

D. Doherty, 2015 .

Increased Frequencies of Circulating IFN-γ-Producing Vδ1(+) and Vδ2(+) γδ T Cells in Patients with Asymptomatic Persistent Hepatitis B Virus Infection.

Margaret A. Taylor, D. Doherty, S. Norris, 2015, Viral immunology.

Circulating CD56dim natural killer cells and CD56+ T cells that produce interferon‐γ or interleukin‐10 are expanded in asymptomatic, E antigen‐negative patients with persistent hepatitis B virus infection

D. Doherty, S. Norris, J. Otegbayo, 2015, Journal of viral hepatitis.

Expansion of innate CD5pos B cells expressing high levels of CD81 in hepatitis C virus infected liver.

D. Doherty, W. Hall, C. O’Farrelly, 2003, Journal of hepatology.

Extratumoral PD-1 blockade does not perpetuate obesity-associated inflammation in esophageal adenocarcinoma.

J. Reynolds, D. Doherty, J. Geoghegan, 2018, Cancer letters.

Dendritic cells: regulators of hepatic immunity or tolerance?

D. Doherty, C. O’Farrelly, 2001, Journal of hepatology.

Hospital-acquired pneumonia after lung resection surgery is associated with characteristic cytokine gene expression.

R. McManus, D. Doherty, M. Lawless, 2011, Chest.

Human V c 9 / V d 2 T cells : Innate adaptors of the immune system

M. Eberl, D. Doherty, B. Moser, 2015 .

Genetic association of the HLA DRB1 gene locus on chromosome 6p21.3 with schizophrenia.

R. Murray, D. Doherty, P. Donaldson, 1996, The American journal of psychiatry.

Activation-induced expression of CD56 by T cells is associated with a reprogramming of cytolytic activity and cytokine secretion profile in vitro.

D. Doherty, L. Madrigal-Estebas, Jane Kelly-Rogers, 2006, Human immunology.

The human liver contains multiple populations of NK cells, T cells, and CD3+CD56+ natural T cells with distinct cytotoxic activities and Th1, Th2, and Th0 cytokine secretion patterns.

D. Doherty, G. Mcentee, O. Traynor, 1999, Journal of immunology.

(E)-4-Hydroxy-3-methyl-but-2 enyl pyrophosphate-stimulated Vγ9Vδ2 T cells possess T helper type 1-promoting adjuvant activity for human monocyte-derived dendritic cells

D. Doherty, M. Dunne, L. Madrigal-Estebas, 2010, Cancer Immunology, Immunotherapy.

Human duodenal epithelial cells constitutively express molecular components of antigen presentation but not costimulatory molecules.

C. Feighery, D. Doherty, C. O’Farrelly, 2002, Human immunology.

Human small intestinal epithelial cells secrete interleukin-7 and differentially express two different interleukin-7 mRNA Transcripts: implications for extrathymic T-cell differentiation.

C. Feighery, R. McManus, D. Doherty, 1997, Human immunology.

Viral Bronchiolitis is Associated With Altered Cytokine Gene Expression and Lymphocyte Activation Status

R. McManus, D. Doherty, M. Carr, 2016, The Pediatric Infectious Disease Journal.

Natural T cells in the human liver: cytotoxic lymphocytes with dual T cell and natural killer cell phenotype and function are phenotypically heterogenous and include Vα24-JαQ and γδ T cell receptor bearing cells

D. Doherty, G. Mcentee, O. Traynor, 1999 .

Major histocompatibility complex associations with primary antiphospholipid syndrome.

D. Vergani, G. Hughes, M. Khamashta, 1992, Arthritis and rheumatism.

Candida albicans Stimulates IL-23 Release by Human Dendritic Cells and Downstream IL-17 Secretion by Vδ1 T Cells

D. Doherty, T. Rogers, F. Mulcahy, 2015, The Journal of Immunology.

1 T Cells d IL-17 Secretion by V Human Dendritic Cells and Downstream Stimulates IL-23 Release by Candida albicans

D. Doherty, T. Rogers, F. Mulcahy, 2015 .

Persistent Changes in Circulating and Intestinal γδ T Cell Subsets, Invariant Natural Killer T Cells and Mucosal-Associated Invariant T Cells in Children and Adults with Coeliac Disease

C. Feighery, D. Doherty, N. Mahmud, 2013, PloS one.

A structural model for TCR recognition of the HLA class II shared epitope sequence implicated in susceptibility to rheumatoid arthritis.

T. Lybrand, J. Penzotti, D. Doherty, 1996, Journal of autoimmunity.

Invariant NKT cells and CD1d+ cells amass in human omentum and are depleted in patients with cancer and obesity

D. Doherty, D. Winter, L. Lynch, 2009, European journal of immunology.

High Frequencies of Functionally Competent Circulating Tax-Specific CD8+ T Cells in Human T Lymphotropic Virus Type 2 Infection

D. Doherty, W. Hall, J. Dean, 2009, The Journal of Immunology.

HIV-1 Tat clade-specific cytokine induction in monocytes/macrophages is not evidenced in total or V&ggr;9V&dgr;2 T lymphocytes

D. Doherty, M. Hennessy, J. Spiers, 2014, AIDS.

HLA phenotypes and gene polymorphisms in juvenile liver disease associated with α1‐antitrypsin deficiency

G. Mieli-Vergani, D. Doherty, P. Donaldson, 1990, Hepatology.

Melatonin as an immunomodulator in children with Down syndrome

D. Doherty, E. Molloy, N. Lagan, 2021, Pediatric Research.

Altered Toll-Like Receptor Signalling in Children with Down Syndrome

D. Doherty, E. Molloy, N. Lagan, 2019, Mediators of inflammation.

Amino acid substitutions at position 38 of the DR beta polypeptide confer susceptibility to and protection from primary sclerosing cholangitis.

R. Vaughan, K. Welsh, D. Doherty, 1992, Hepatology.

Infection Human T Lymphotropic Virus Type 2 T Cells in + Circulating Tax-Specific CD 8 High Frequencies of Functionally Competent and

D. Doherty, W. Hall, J. Dean, 2009 .

Selective reduction of natural killer cells and T cells expressing inhibitory receptors for MHC class I in the livers of patients with hepatic malignancy

D. Doherty, G. Mcentee, O. Traynor, 2002, Cancer Immunology, Immunotherapy.

Natural T cells in the human liver: cytotoxic lymphocytes with dual T cell and natural killer cell phenotype and function are phenotypically heterogenous and include Valpha24-JalphaQ and gammadelta T cell receptor bearing cells.

D. Doherty, G. Mcentee, O. Traynor, 1999, Human immunology.

Interleukin 12 (IL-12) is increased in tumour bearing human liver and expands CD8(+) and CD56(+) T cells in vitro but not in vivo.

D. Doherty, G. Mcentee, O. Traynor, 2004, Cytokine.

Hepatic interleuklin 15 (IL‐15) expression: implications for local NK/NKT cell homeostasis and development

D. Doherty, G. Mcentee, O. Traynor, 2004, Clinical and experimental immunology.

Selective Expansion and Partial Activation of Human NK Cells and NK Receptor-Positive T Cells by IL-2 and IL-151

C. Feighery, D. Doherty, J. Dunne, 2001, The Journal of Immunology.

IL-2 and IL-15 THuman NK Cells and NK Receptor-Positive Selective Expansion and Partial Activation of

C. Feighery, D. Doherty, J. Dunne, 2001 .

HLA-DRB genes and antiribosomal P antibodies in systemic lupus erythematosus.

D. Doherty, L. Teh, B. Williams, 1994, British journal of rheumatology.

SARS-CoV-2 spike and nucleocapsid proteins fail to activate human dendritic cells or γδ T cells

Seamus J. Martin, D. Doherty, A. Long, 2022, PloS one.

Mucosal-associated invariant T cells are depleted and functionally altered in patients with common variable immunodeficiency.

C. Feighery, D. Doherty, J. Dunne, 2017, Clinical immunology.

Isolation of lymphocytes from normal adult human liver suitable for phenotypic and functional characterization.

D. Doherty, G. Mcentee, O. Traynor, 2000, Journal of immunological methods.

Increased systemic inflammation in children with Down syndrome.

D. Doherty, E. Molloy, N. Lagan, 2019, Cytokine.

Novel thioglycoside analogs of &agr;-galactosylceramide stimulate cytotoxicity and preferential Th1 cytokine production by human invariant natural killer T cells

D. Doherty, C. O’Reilly, A. Melo, 2018, Glycobiology.

Cutting Edge: CD1d Restriction and Th1/Th2/Th17 Cytokine Secretion by Human Vδ3 T Cells

D. Doherty, M. Exley, D. O'Shea, 2013, The Journal of Immunology.

CD 1 d restriction and Th 1 / Th 2 / Th 17 cytokine secretion by human V δ 3 T cells

D. Doherty, M. Exley, D. O'Shea, 2013 .

Activation of human invariant natural killer T cells with a thioglycoside analogue of α-galactosylceramide.

D. Doherty, P. Fallon, M. Exley, 2011, Clinical immunology.

Preferential Th1 Cytokine Profile of Phosphoantigen-Stimulated Human Vγ9Vδ2 T Cells

D. Doherty, M. Dunne, L. Madrigal-Estebas, 2011, Mediators of inflammation.

Selective effects of radiotherapy on viability and function of invariant natural killer T cells in vitro.

S. Maher, D. Doherty, S. O'leary, 2020, Radiotherapy and Oncology.

Altered distributions and functions of natural killer T cells and γδ T cells in neonates with neonatal encephalopathy, in school-age children at follow-up, and in children with cerebral palsy

D. Doherty, E. Molloy, E. Ryan, 2021, Journal of Neuroimmunology.

Human Invariant NKT Cell Subsets Differentially Promote Differentiation, Antibody Production, and T Cell Stimulation by B Cells In Vitro

D. Doherty, A. Atzberger, M. Exley, 2013, The Journal of Immunology.

by B Cells In Vitro Antibody Production, and T Cell Stimulation Differentially Promote Differentiation, Human Invariant NKT Cell Subsets

D. Doherty, A. Atzberger, M. Exley, 2013 .

CD1 expression and CD1-restricted T cell activity in normal and tumour-bearing human liver

D. Doherty, S. Porcelli, M. Exley, 2007, Cancer Immunology, Immunotherapy.

Differential expression and upregulation of interleukin-1alpha, interleukin-1beta and interleukin-6 by freshly isolated human small intestinal epithelial cells.

C. Feighery, D. Doherty, C. O’Farrelly, 2002, Mediators of inflammation.

A novel method to identify and characterise peptide mimotopes of heat shock protein 70-associated antigens

Stephen Todryk, D. Doherty, T. James, 2006, Journal of immune based therapies and vaccines.

REVIEW: Genetic Bases of Autoimmune Hepatitis

D. Doherty, P. Donaldson, A. Czaja, 2002, Digestive Diseases and Sciences.

Influence of human leukocyte antigen matching on liver allograft survival and rejection: “The dualistic effect”

B. Portmann, D. Doherty, P. Donaldson, 1993, Hepatology.

Distinct subpopulations of gamma delta T cells are present in normal and tumor-bearing human liver.

D. Doherty, C. O’Farrelly, T. Kenna, 2004, Clinical immunology.

Major histocompatibility complex genes and susceptibility to systemic lupus erythematosus in southern Chinese.

D. Vergani, K. Welsh, A. Demaine, 1992, Arthritis and rheumatism.

Antigen-specific immune tolerance in the liver

D. Doherty, 2019, Nature Biomedical Engineering.

Autoimmune hepatitis in childhood: A 20‐year experience

D. Vergani, B. Portmann, G. Mieli-Vergani, 1997, Hepatology.

Susceptibility to autoimmune chronic active hepatitis: Human leukocyte antigens DR4 and A1‐B8‐DR3 are independent risk factors

Roger Williams, P. Johnson, D. Doherty, 1991, Hepatology.

Unconventional T cells - New players in antifungal immunity.

D. Doherty, J. Loeffler, T. Rogers, 2021, Clinical immunology.

T Cells in Adult and Childhood Obesity Production by Mucosal-Associated Invariant Altered Distribution and Increased IL-17

E. Carolan, D. Doherty, D. Winter, 2015 .

NKT Cells from Normal and Tumor-Bearing Human Livers Are Phenotypically and Functionally Distinct from Murine NKT Cells 1

D. Doherty, S. Porcelli, Y. Koezuka, 2003, The Journal of Immunology.

Functionally Distinct from Murine NKT Cells Human Livers Are Phenotypically and NKT Cells from Normal and Tumor-Bearing

D. Doherty, S. Porcelli, Y. Koezuka, 2003 .

HLA DPB polymorphism in primary sclerosing cholangitis and primary biliary cirrhosis

D. Doherty, P. Donaldson, J. Underhill, 1995, Hepatology.

The molecular genetics of autoimmune liver disease

D. Doherty, P. Donaldson, J. Underhill, 1994, Hepatology.

Interleukin-15 is associated with disease severity in viral bronchiolitis

R. Janssen, R. McManus, G. Blackshields, 2015, European Respiratory Journal.

The major histocompatibility complex influences the development of chronic liver disease in male children and young adults with cystic fibrosis.

D. Doherty, P. Donaldson, A. Eddleston, 1995, Journal of hepatology.

Human Vγ9/Vδ2 T cells: Innate adaptors of the immune system.

M. Eberl, D. Doherty, B. Moser, 2015, Cellular immunology.

Altered Distribution and Increased IL-17 Production by Mucosal-Associated Invariant T Cells in Adult and Childhood Obesity

E. Carolan, D. Doherty, D. Winter, 2015, The Journal of Immunology.

Distinct and Overlapping Effector Functions of Expanded Human CD4+, CD8α+ and CD4-CD8α- Invariant Natural Killer T Cells

Ann Atzberger, Steven A. Porcelli, C. Feighery, 2011, PloS one.

Polymorphism in the human complement C4 genes and genetic susceptibility to autoimmune hepatitis.

D. Vergani, G. Mieli-Vergani, A. Demaine, 1994, Autoimmunity.

Altered natural killer cell subset distributions in resolved and persistent hepatitis C virus infection following single source exposure

D. Doherty, C. O’Farrelly, L. Madrigal-Estebas, 2008, Gut.

Retinoic acid induction of CD1d expression primes chronic lymphocytic leukemia B cells for killing by CD8+ invariant natural killer T cells.

D. Doherty, P. Browne, V. O’Reilly, 2017, Clinical immunology.

HLA genotyping of colorectal carcinoma in the Chinese population.

D. Doherty, J. Bidwell, K. Hui, 1992, Human immunology.

Structural basis of specificity and degeneracy of T cell recognition: pluriallelic restriction of T cell responses to a peptide antigen involves both specific and promiscuous interactions between the T cell receptor, peptide, and HLA-DR.

T. Lybrand, J. Penzotti, D. Doherty, 1998, Journal of immunology.

Diverse populations of T cells with NK cell receptors accumulate in the human intestine in health and in colorectal cancer

K. Sheahan, D. Doherty, J. Hyland, 2004, European journal of immunology.

Epigenetic induction of CD1d expression primes lung cancer cells for killing by invariant natural killer T cells

J. Keane, D. Doherty, S. Gray, 2018, Oncoimmunology.

Immunity, tolerance and autoimmunity in the liver: A comprehensive review.

D. Doherty, 2016, Journal of autoimmunity.

A Short Primer on Fundamental Immunology

D. Doherty, C. O’Farrelly, 2007 .

Human Vδ3+ γδ T cells induce maturation and IgM secretion by B cells.

D. Doherty, A. Melo, E. Breen, 2018, Immunology letters.

NKT Cells from Normal and Tumor-Bearing Human Livers Are Phenotypically and Functionally Distinct from Murine NKT Cells

D. Doherty, S. Porcelli, Y. Koezuka, 2003, The Journal of Immunology.

HLA DQA, DQB, and DRB genotyping by oligonucleotide analysis: distribution of alleles and haplotypes in British caucasoids.

R. Vaughan, D. Doherty, P. Donaldson, 1992, Human immunology.

Distinct hepatic myeloid and lymphoid cell repertoires are associated with susceptibility and resistance to Ascaris infection

D. Doherty, C. Holland, O. Sowemimo, 2021, Parasitology.

Hepatitis C virus – T‐cell responses and viral escape mutations

D. Doherty, D. Kelleher, A. Long, 2012, European journal of immunology.

Hepatitis C virus targets the T cell secretory machinery as a mechanism of immune evasion

J. Conroy, J. McKeating, D. Doherty, 2011, Hepatology.

Unmet needs persist in pediatric HIV programs: lessons from selected case studies in Uganda.

D. Doherty, N. Tumwesigye, A. Kambugu, 2017, AIDS (London).

T-cell receptor constant beta germline gene polymorphisms and susceptibility to autoimmune hepatitis.

G. Mieli-Vergani, M. Hibberd, A. Demaine, 1994, Gastroenterology.

Human Natural Killer cell expression of ULBP2 is associated with a mature functional phenotype.

J. Keane, D. Doherty, S. Keating, 2016, Human immunology.

Genetic bases of autoimmune hepatitis.

D. Doherty, P. Donaldson, A. Czaja, 2002, Digestive diseases and sciences.

Allelic sequence variation in the HLA class II genes and proteins in patients with autoimmune hepatitis

Roger Williams, G. Mieli-Vergani, P. Johnson, 1994, Hepatology.

The role of lymphocytes in neonatal encephalopathy

D. Doherty, E. Molloy, A. Melo, 2021, Brain, behavior, & immunity - health.

Decrease in hepatic CD56(+) T cells and V alpha 24(+) natural killer T cells in chronic hepatitis C viral infection.

D. Doherty, Y. Volkov, G. Mcentee, 2002, Journal of hepatology.

Decrease in hepatic CD 56 1 T cells and V a 24 1 natural killer T cells in chronic hepatitis C viral infection

D. Doherty, Y. Volkov, G. Mcentee, 2002 .

Tissue distribution of γδ T cell subsets in oesophageal adenocarcinoma.

J. Reynolds, D. Doherty, A. Bhardwaj, 2021, Clinical immunology.

Characteristic Cytokine Gene Expression Resection Surgery Is Associated With Hospital-Acquired Pneumonia After Lung

D. Doherty, M. Lawless, D. Kelleher, 2011 .

Cortisol does not mediate the suppressive effects of psychiatric morbidity on natural killer cell activity: a cross-sectional study of patients with early breast cancer

A. Hill, D. Doherty, P. Fitzpatrick, 2004, Psychological Medicine.

Characterising Cytokine Gene Expression Signatures in Patients with Severe Sepsis

R. McManus, D. Doherty, P. Stordeur, 2013, Mediators of inflammation.

Post-operative infection and sepsis in humans is associated with deficient gene expression of γc cytokines and their apoptosis mediators

R. McManus, D. Doherty, P. Stordeur, 2011, Critical care.

Characterisation of the pro-inflammatory cytokine signature in severe COVID-19

D. Doherty, A. O’Halloran, R. Kenny, 2023, Frontiers in Immunology.

Human Leukocyte Antigen Profile Predicts Severity of Autoimmune Liver Disease in Children of European Ancestry

D. Vergani, M. Mcphail, G. Mieli-Vergani, 2021, Hepatology.

CD3ε Expression Defines Functionally Distinct Subsets of Vδ1 T Cells in Patients With Human Immunodeficiency Virus Infection

D. Doherty, A. Long, T. Rogers, 2018, Front. Immunol..

Type 2 Diabetes Mellitus and Latent Tuberculosis Infection Moderately Influence Innate Lymphoid Cell Immune Responses in Uganda

D. Doherty, M. Hepworth, S. Cose, 2021, Frontiers in Immunology.

Proof of concept nanotechnological approach to in vitro targeting of malignant melanoma for enhanced immune checkpoint inhibition

D. Doherty, S. Gray, N. Binsaleh, 2023, Scientific reports.

Innate Lymphocyte Th1 and Th17 Responses in Elderly Hospitalised Patients with Infection and Sepsis

J. D. Coakley, R. McManus, D. Doherty, 2020, Vaccines.

Human Vδ2+ γδ T Cells Differentially Induce Maturation, Cytokine Production, and Alloreactive T Cell Stimulation by Dendritic Cells and B Cells

D. Doherty, A. Petrasca, 2014, Front. Immunol..

Altered endotoxin responsiveness in healthy children with Down syndrome

D. Doherty, E. Molloy, N. Lagan, 2018, BMC Immunology.

136 Evidence for a resistance locus for schizophrenia close to the HLA DQB1 and DRB1 gene loci on chromosome 6p21.3

R. Murray, D. Doherty, P. Donaldson, 1997, Schizophrenia Research.

Differential expression and upregulation of interleukin-1 a , interleukin-1 b and interleukin-6 by freshly isolated human small intestinal epithelial cells

C. Feighery, D. Doherty, C. O’Farrelly, 2014 .

Alterations in circulating lymphoid cell populations in systemic small vessel vasculitis are non‐specific manifestations of renal injury

D. Doherty, A. Melo, M. Little, 2018, Clinical and experimental immunology.

Antigen-specific immune tolerance in the liver

D. Doherty, 2019, Nature Biomedical Engineering.

A novel method to identify and characterise peptide mimotopes of heat shock protein 70-associated antigens

D. Doherty, T. James, S. Todryk, 2007 .