A. Roussel

发表

A hyperthermostable D-ribose-5-phosphate isomerase from Pyrococcus horikoshii characterization and three-dimensional structure.

Kazuhiko Ishikawa, Alain Roussel, Christian Cambillau, 2002, Structure.

Specific Characterization of Substrate and Inhibitor Binding Sites of a Glycosyl Hydrolase Family 11 Xylanase fromAspergillus niger *

Jean-Guy Berrin, Alain Roussel, Gary Williamson, 2002, The Journal of Biological Chemistry.

Conformational change and protein–protein interactions of the fusion protein of Semliki Forest virus

J. Lepault, F. Rey, D. Gibbons, 2004, Nature.

A phospholipase A1 antibacterial Type VI secretion effector interacts directly with the C‐terminal domain of the VgrG spike protein for delivery

Alain Roussel, Christian Cambillau, Van Son Nguyen, 2016, Molecular microbiology.

Structural analysis of xylanase inhibitor protein I (XIP-I), a proteinaceous xylanase inhibitor from wheat (Triticum aestivum, var. Soisson).

Alain Roussel, Gary Williamson, N. Juge, 2003, The Biochemical journal.

Multifunctional Natural Killer Cell Engagers Targeting NKp46 Trigger Protective Tumor Immunity

A. Roussel, É. Vivier, L. Gauthier, 2019, Cell.

Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex

A. Desmyter, C. Cambillau, S. Spinelli, 2017, Nature Microbiology.

Lipoprotein lipase. Molecular model based on the pancreatic lipase x-ray structure: consequences for heparin binding and catalysis.

J. Lalouel, H. van Tilbeurgh, H. Tilbeurgh, 1994, The Journal of biological chemistry.

Crystallization and preliminary X-ray analysis of monalysin, a novel β-pore-forming toxin from the entomopathogen Pseudomonas entomophila.

B. Lemaître, R. Vincentelli, A. Roussel, 2013, Acta crystallographica. Section F, Structural biology and crystallization communications.

Macromolecular interactions in vitro, comparing classical and novel approaches

A. Velázquez‐Campoy, P. Soule, M. Aumont-Nicaise, 2021, European Biophysics Journal.

Structure of the host-recognition device of Staphylococcus aureus phage ϕ11

C. Cambillau, S. Spinelli, T. Stehle, 2016, Scientific Reports.

Crystal Structure and Self-Interaction of the Type VI Secretion Tail-Tube Protein from Enteroaggregative Escherichia coli

C. Cambillau, S. Spinelli, A. Roussel, 2014, PloS one.

A new non-classical fold of varroa odorant-binding proteins reveals a wide open internal cavity

S. Arena, A. Scaloni, C. Cambillau, 2021, Scientific Reports.

Antigenic Peptide in an Unprecedented Mode Anchors the Backbone of an Octameric MHC Peptide-Binding Groove k The H-2K

B. Malissen, A. Roussel, C. Kellenberger, 2005 .

The H-2Kk MHC Peptide-Binding Groove Anchors the Backbone of an Octameric Antigenic Peptide in an Unprecedented Mode12

B. Malissen, A. Roussel, C. Kellenberger, 2005, The Journal of Immunology.

Novel ACTN1 variants in cases of thrombocytopenia

A. Roussel, M. Poggi, M. Alessi, 2019, Human mutation.

Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus.

F. Rey, M. Mathieu, R. Francesco, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of a TET-like aminopeptidase complex from the hyperthermophilic archaeon Pyrococcus horikoshii.

G. Schoehn, B. Franzetti, A. Roussel, 2005, Biochemistry.

X-ray Structure and Ligand Binding Study of a Moth Chemosensory Protein*

Alain Roussel, T. A. Jones, Mariella Tegoni, 2002, The Journal of Biological Chemistry.

Biogenesis and structure of a type VI secretion membrane core complex

A. Desmyter, C. Cambillau, S. Spinelli, 2015, Nature.

SARS-CoV-2 detection using a nanobody-functionalized voltammetric device

R. Boukherroub, D. Devos, C. Cambillau, 2022, Communications Medicine.

Three‐Dimensionnal structures of complexes of Lathyrus ochrus isolectin I with glucose and mannose: Fine specificity of the monosaccharide‐binding site

C. Cambillau, J. Fontecilla-Camps, P. Rougé, 1994, Proteins: Structure, Function, and Bioinformatics.

Functional importance of Asp37 from a family 11 xylanase in the binding to two proteinaceous xylanase inhibitors from wheat.

N. Juge, A. Durand, K. Gebruers, 2004, FEMS microbiology letters.

The Dual Nature of the Wheat Xylanase Protein Inhibitor XIP-I

Alain Roussel, Tariq Tahir, Gary Williamson, 2004, Journal of Biological Chemistry.

Biosynthetic proteins targeting the SARS-CoV-2 spike as anti-virals

N. Meunier, X. de Lamballerie, J. Dubuisson, 2022, bioRxiv.

Towards a complete structural deciphering of Type VI secretion system.

C. Cambillau, A. Roussel, E. Cascales, 2018, Current opinion in structural biology.

A simple and versatile microfluidic device for efficient biomacromolecule crystallization and structural analysis by serial crystallography

J. A. Gavira, B. Lorber, C. Mueller-Dieckmann, 2019, IUCrJ.

PGRP-LC Isoforms and PGRP-LE by Drosophila Gram-Negative Infection in Tissue- and Ligand-Specific Sensing of

A. Roussel, M. Poidevin, Lemaitre Claudine Neyen, 2012 .

Bile-mediated activation of the acrAB and tolC multidrug efflux genes occurs mainly through transcriptional derepression of ramA in Salmonella enterica serovar Typhimurium.

M. Maurel, A. Roussel, E. Giraud, 2014, The Journal of antimicrobial chemotherapy.

Type IX secretion system PorM and gliding machinery GldM form extended arches spanning the periplasmic space

A. Desmyter, C. Cambillau, A. Roussel, 2020 .

Antigenic Peptide in an Unprecedented Mode Anchors the Backbone of an Octameric MHC Peptide-Binding Groove k The H-2K

B. Malissen, A. Roussel, C. Kellenberger, 2005 .

Structure-Function Analysis of Grass Clip Serine Protease Involved in Drosophila Toll Pathway Activation*

A. Roussel, J. Reichhart, T. Jouenne, 2011, The Journal of Biological Chemistry.

Development and evaluation of a sublingual tablet based on recombinant Bet v 1 in birch pollen‐allergic patients

A. Roussel, M. Pallardy, P. Moingeon, 2015, Allergy.

TssA: The cap protein of the Type VI secretion system tail

C. Cambillau, A. Roussel, L. Journet, 2017, BioEssays : news and reviews in molecular, cellular and developmental biology.

Structure Prediction and Analysis of Hepatitis E Virus Non-Structural Proteins from the Replication and Transcription Machinery by AlphaFold2

C. Cambillau, A. Roussel, I. Imbert, 2022, Viruses.

Rat kidney acylase I: further characterisation and mutation studies on the involvement of Glu 147 in the catalytic process.

A. Durand, A. Roussel, T. Giardina, 2003, Biochimie.

Distinct orientation of the alloreactive monoclonal CD8 T cell activation program by three different peptide/MHC complexes

Alain Roussel, Bernard Malissen, D. Hunt, 2006, European journal of immunology.

Digestive lipases: from three-dimensional structure to physiology.

C Cambillau, R. Verger, C. Cambillau, 2000, Biochimie.

Complexation of Two Proteic Insect Inhibitors to the Active Site of Chymotrypsin Suggests Decoupled Roles for Binding and Selectivity*

M. Mathieu, C. Cambillau, A. Roussel, 2001, The Journal of Biological Chemistry.

Camelid nanobodies: killing two birds with one stone.

A. Desmyter, C. Cambillau, S. Spinelli, 2015, Current opinion in structural biology.

The structure of an entire noncovalent immunoglobulin kappa light-chain dimer (Bence-Jones protein) reveals a weak and unusual constant domains association.

J. Navaza, C. Cambillau, S. Spinelli, 1999, European journal of biochemistry.

Crystal Structure of the Open Form of Dog Gastric Lipase in Complex with a Phosphonate Inhibitor*

P. Berna, R. Verger, C. Cambillau, 2002, The Journal of Biological Chemistry.

Resolution of the structure of the allergenic and antifungal banana fruit thaumatin-like protein at 1.7-A.

P. Rougé, F. Payan, A. Roussel, 2006, Biochimie.

Crystal Structure of Human Gastric Lipase and Model of Lysosomal Acid Lipase, Two Lipolytic Enzymes of Medical Interest*

R. Verger, C. Cambillau, A. Roussel, 1999, The Journal of Biological Chemistry.

A hypothetical complex between crystalline flavocytochrome b2 and Cytochrome c

C. Cambillau, S. White, A. Roussel, 1993, Proteins.

Cas9 Allosteric Inhibition by the Anti-CRISPR Protein AcrIIA6.

M. Bolognesi, Y. Doyon, C. Cambillau, 2019, Molecular cell.

Structure-activity relationship within the serine protease inhibitors of the pacifastin family.

A. Roussel, C. Kellenberger, 2005, Protein and peptide letters.

Selective inhibition of trypsins by insect peptides: role of P6-P10 loop.

A. Roussel, C. Kellenberger, H. Darbon, 2003, Biochemistry.

The role of the surface ligand on the performance of electrochemical SARS-CoV-2 antigen biosensors

R. Boukherroub, D. Devos, C. Cambillau, 2021, Analytical and Bioanalytical Chemistry.

The N-terminal Domain of Drosophila Gram-negative Binding Protein 3 (GNBP3) Defines a Novel Family of Fungal Pattern Recognition Receptors*

J. Latgé, A. Roussel, V. Aimanianda, 2009, The Journal of Biological Chemistry.

X-ray and Cryo-electron Microscopy Structures of Monalysin Pore-forming Toxin Reveal Multimerization of the Pro-form*

B. Lemaître, C. Cambillau, A. Roussel, 2015, The Journal of Biological Chemistry.

Structure and Activity of Rat Pancreatic Lipase-related Protein 2*

R. Verger, C. Cambillau, A. Roussel, 1998, The Journal of Biological Chemistry.

Structural and Biochemical Analyses of Glycoside Hydrolase Families 5 and 26 β-(1,4)-Mannanases from Podospora anserina Reveal Differences upon Manno-oligosaccharide Catalysis*

Jean-Guy Berrin, Alain Roussel, Anna Rosengren, 2013, The Journal of Biological Chemistry.

Structural basis for the substrate selectivity of pancreatic lipases and some related proteins.

H. van Tilbeurgh, H. Tilbeurgh, R. Verger, 1998, Biochimica et biophysica acta.

Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies.

A. Roussel, L. Gros, A. Docquier, 2019, Cell reports.

Characterization of the Porphyromonas gingivalis Type IX Secretion Trans-envelope PorKLMNP Core Complex*

C. Cambillau, A. Roussel, E. Cascales, 2017, The Journal of Biological Chemistry.

Functional Analysis of PGRP-LA in Drosophila Immunity

B. Lemaître, A. Roussel, M. Poidevin, 2013, PloS one.

Tissue- and Ligand-Specific Sensing of Gram-Negative Infection in Drosophila by PGRP-LC Isoforms and PGRP-LE

B. Lemaître, A. Roussel, M. Poidevin, 2012, The Journal of Immunology.

Crystal Structure of Diedel, a Marker of the Immune Response of Drosophila melanogaster

A. Roussel, J. Imler, C. Hétru, 2012, PloS one.

Extracellular vesicles as a platform to study cell-surface membrane proteins.

A. Roussel, L. Gauthier, B. Amigues, 2020, Methods.

Cytokine Diedel and a viral homologue suppress the IMD pathway in Drosophila

M. Boutros, A. Roussel, J. Marques, 2016, Proceedings of the National Academy of Sciences.

Preanalytical Issues and Cycle Threshold Values in SARS-CoV-2 Real-Time RT-PCR Testing: Should Test Results Include These?

R. Boukherroub, D. Devos, C. Cambillau, 2021, ACS omega.

Solution conformation of human neuropeptide Y by 1H nuclear magnetic resonance and restrained molecular dynamics.

C. Cambillau, A. Roussel, H. Darbon, 1992, European journal of biochemistry.

Crystal structure of greglin, a novel non‐classical Kazal inhibitor, in complex with subtilisin

M. Cadene, A. Roussel, B. Korkmaz, 2012, The FEBS journal.

The Fusion Glycoprotein Shell of Semliki Forest Virus An Icosahedral Assembly Primed for Fusogenic Activation at Endosomal pH

J. Navaza, F. Rey, S. Fuller, 2001, Cell.

Membrane-remodeling protein ESCRT-III homologs incarnate the evolution and morphogenesis of multicellular magnetotactic bacteria

C. Santini, Long-Fei Wu, A. Roussel, 2022, bioRxiv.

Monalysin, a Novel ß-Pore-Forming Toxin from the Drosophila Pathogen Pseudomonas entomophila, Contributes to Host Intestinal Damage and Lethality

B. Lemaître, R. Vincentelli, F. G. van der Goot, 2011, PLoS pathogens.

CRYStallize: a crystallographic symmetry display and handling subpackage in TOM/FRODO.

A Roussel, J C Fontecilla-Camps, C Cambillau, 1990, Journal of molecular graphics.

CRYSTAL STRUCTURE OF HUMAN GASTRIC LIPASE

R. Verger, C. Cambillau, A. Roussel, 2000 .

Molecular Engineering of Fungal GH5 and GH26 Beta-(1,4)-Mannanases toward Improvement of Enzyme Activity

A. Roussel, S. Bozonnet, J. Berrin, 2013, PloS one.

How much can a T‐cell antigen receptor adapt to structurally distinct antigenic peptides?

B. Malissen, A. Roussel, P. A. van der Merwe, 2007, The EMBO journal.

Activity and Crystal Structure of the Adherent-Invasive Escherichia coli Tle3/Tli3 T6SS Effector/Immunity Complex Determined Using an AlphaFold2 Predicted Model

C. Cambillau, A. Roussel, L. Journet, 2023, International journal of molecular sciences.

Expression, refolding, crystallization and preliminary crystallographic study of MHC H-2Kk complexed with octapeptides and nonapeptides.

A. Roussel, C. Kellenberger, S. Porciero, 2004, Acta crystallographica. Section D, Biological crystallography.

Reactivation of the totally inactive pancreatic lipase RP1 by structure‐predicted point mutations

R. Verger, C. Cambillau, A. Roussel, 1998, Proteins.

A Cutinase from Trichoderma reesei with a lid-covered active site and kinetic properties of true lipases.

C. Cambillau, A. Roussel, A. Westerholm-Parvinen, 2014, Journal of molecular biology.

Probing Conformational Changes and Interfacial Recognition Site of Lipases With Surfactants and Inhibitors.

C. Cambillau, S. Longhi, A. Roussel, 2017, Methods in enzymology.

Gastric lipase: crystal structure and activity.

R. Verger, C. Cambillau, A. Roussel, 1999, Biochimica et biophysica acta.

The Drosophila peptidoglycan‐recognition protein LF interacts with peptidoglycan‐recognition protein LC to downregulate the Imd pathway

R. Vincentelli, A. Roussel, J. Royet, 2011, EMBO reports.

A medium-throughput crystallization approach.

Renaud Vincentelli, Alain Roussel, Eric Blanc, 2002, Acta crystallographica. Section D, Biological crystallography.

Structure and interactions at the viral surface of the envelope protein E1 of Semliki Forest virus.

F. Rey, J. Lescar, M. Vaney, 2006, Structure.

Camelid nanobodies used as crystallization chaperones for different constructs of PorM, a component of the type IX secretion system from Porphyromonas gingivalis.

A. Desmyter, C. Cambillau, A. Roussel, 2017, Acta crystallographica. Section F, Structural biology communications.

Structure of Locusta migratoria protease inhibitor 3 (LMPI-3) in complex with Fusarium oxysporum trypsin.

A. Roussel, C. Kellenberger, P. Leone, 2008, Acta Crystallographica Section D: Biological Crystallography.

Binding of the RamR Repressor to Wild-Type and Mutated Promoters of the ramA Gene Involved in Efflux-Mediated Multidrug Resistance in Salmonella enterica Serovar Typhimurium

F. Culard, B. Castaing, M. Maurel, 2011, Antimicrobial Agents and Chemotherapy.

An Archaeal Peptidase Assembles into Two Different Quaternary Structures

R. Ruigrok, G. Schoehn, B. Franzetti, 2006, Journal of Biological Chemistry.

Sensing of COVID-19 spike protein in nasopharyngeal samples using a portable surface plasmon resonance diagnostic system

Ludovic S. Live, R. Boukherroub, D. Devos, 2022, Sensors & Diagnostics.

Unraveling the Self-Assembly of the Pseudomonas aeruginosa XcpQ Secretin Periplasmic Domain Provides New Molecular Insights into Type II Secretion System Secreton Architecture and Dynamics

A. Desmyter, C. Cambillau, A. Roussel, 2017, mBio.

Emergence of a subfamily of xylanase inhibitors within glycoside hydrolase family 18

Bernard Henrissat, Alain Roussel, B. Henrissat, 2005, The FEBS journal.

Crystal structure of Drosophila PGRP-SD suggests binding to DAP-type but not lysine-type peptidoglycan.

A. Roussel, C. Hétru, J. Royet, 2008, Molecular immunology.

Inhibition of Type VI Secretion by an Anti-TssM Llama Nanobody

A. Desmyter, C. Cambillau, S. Spinelli, 2015, PloS one.

Anchoring the T6SS to the cell wall: Crystal structure of the peptidoglycan binding domain of the TagL accessory protein

C. Cambillau, S. Spinelli, A. Roussel, 2021, PloS one.

Crystal structure of Type IX secretion system PorE C-terminal domain from Porphyromonas gingivalis in complex with a peptidoglycan fragment

C. Cambillau, A. Roussel, N. T. Trinh, 2020, Scientific Reports.

Crystallization and preliminary X-ray analysis of the C-terminal fragment of PorM, a subunit of the Porphyromonas gingivalis type IX secretion system.

C. Cambillau, A. Roussel, E. Cascales, 2015, Acta crystallographica. Section F, Structural biology communications.

Tissue-Specific Regulation of Drosophila NF-κB Pathway Activation by Peptidoglycan Recognition Protein SC

B. Charroux, A. Roussel, Florence Capo, 2015, Journal of Innate Immunity.

Type IX secretion system PorM and gliding machinery GldM form arches spanning the periplasmic space

A. Desmyter, C. Cambillau, A. Roussel, 2018, Nature Communications.

Production, crystallization and X-ray diffraction analysis of a complex between a fragment of the TssM T6SS protein and a camelid nanobody.

A. Desmyter, C. Cambillau, S. Spinelli, 2015, Acta crystallographica. Section F, Structural biology communications.

Crystal structure of the streptococcal superantigen SPE-C: dimerization and zinc binding suggest a novel mode of interaction with MHC class II molecules

H. Baker, E. Baker, B. Anderson, 1997, Nature Structural Biology.

Structural and functional analyses of the Porphyromonas gingivalis type IX secretion system PorN protein

A. Roussel, E. Cascales, P. Leone, 2022, The Journal of biological chemistry.

Rapid access to an updated biological macromolecule crystallization database through artificial intelligence

J. Fontecilla-Camps, A. Roussel, L. Serre, 1990 .

Conformational flexibility of a scorpion toxin active on mammals and insects: A circular dichroism study

C. Granier, A. Roussel, H. Rochat, 1990, Proteins.

Expression, purification, crystallization and preliminary crystallographic analysis of a deblocking aminopeptidase from Pyrococcus horikoshii.

B. Franzetti, A. Roussel, Kazushige Mori, 2005, Acta Crystallographica. Section F : Structural Biology and Crystallization Communications.

An inactive pancreatic lipase-related protein is activated into a triglyceride-lipase by mutagenesis based on the 3-D structure.

R. Verger, C. Cambillau, A. Roussel, 1998, Chemistry and physics of lipids.