J. Whitelegge

发表

Discovery of a thermophilic protein complex stabilized by topologically interlinked chains.

Duilio Cascio, L. J. Perry, Todd O Yeates, 2007, Journal of molecular biology.

Side-chain contributions to membrane protein structure and stability.

Duan Yang, Julian P Whitelegge, James U Bowie, 2004, Journal of molecular biology.

The evolution of transmembrane helix kinks and the structural diversity of G protein-coupled receptors.

Duan Yang, Julian P Whitelegge, James U Bowie, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Molecular Modelling Studies on the Binding of Phenylurea Inhibitors to the D 1 Protein of Photosystem II

A. Crofts, J. Whitelegge, H. Robinson, 1990, Zeitschrift fur Naturforschung. C, Journal of biosciences.

Deconvolution and Database Search of Complex Tandem Mass Spectra of Intact Proteins

P. Pevzner, V. Bafna, P. Dorrestein, 2010, Molecular & Cellular Proteomics.

Protein-Sequence Polymorphisms and Post-translational Modifications in Proteins from Human Saliva using Top-Down Fourier-transform Ion Cyclotron Resonance Mass Spectrometry.

F. Halgand, D. Wong, J. Whitelegge, 2007, International journal of mass spectrometry.

Increased coverage in the transmembrane domain with activated-ion electron capture dissociation for top-down Fourier-transform mass spectrometry of integral membrane proteins.

J. Whitelegge, V. Zabrouskov, 2007, Journal of proteome research.

Metal-free superoxide dismutase forms soluble oligomers under physiological conditions: A possible general mechanism for familial ALS

I. Bertini, J. Valentine, L. Banci, 2007, Proceedings of the National Academy of Sciences.

A novel chloroplast super-complex consisting of the ATP synthase and photosystem I reaction center

J. Whitelegge, S. Singh, W. Cramer, 2019, bioRxiv.

An examination of wild-type SOD1 in modulating the toxicity and aggregation of ALS-associated mutant SOD1

D. Borchelt, J. Whitelegge, A. Durazo, 2010, Human molecular genetics.

Proline substitutions are not easily accommodated in a membrane protein.

Duan Yang, James U Bowie, J. Bowie, 2004, Journal of molecular biology.

Investigation of Anti-SOD1 Antibodies Yields New Structural Insight into SOD1 Misfolding and Surprising Behavior of the Antibodies Themselves.

G. Bitan, J. Whitelegge, N. Cashman, 2018, ACS chemical biology.

Atomic View of a Toxic Amyloid Small Oligomer

David Eisenberg, Meytal Landau, Duilio Cascio, 2012, Science.

Disulfide connectivity in cerebroside sulfate activator is not necessary for biological activity or alpha-helical content but is necessary for trypsin resistance and strong ligand binding.

A. Waring, J. Whitelegge, K. Faull, 2000, Archives of biochemistry and biophysics.

Hydrogen-deuterium exchange signature of porcine cerebroside sulfate activator protein.

A. Waring, J. Whitelegge, K. Faull, 2000, Journal of mass spectrometry : JMS.

Preparation of the cerebroside sulfate activator (CSAct or saposin B) from human urine.

A. Waring, J. Whitelegge, C. Lombardo, 1999, Molecular genetics and metabolism.

Cerebroside sulfate activator protein (Saposin B): chromatographic and electrospray mass spectrometric properties.

K. Standing, A. Waring, J. Whitelegge, 1999, Journal of Mass Spectrometry.

Monomeric Light-chain Variable Domains Formation of Amyloid Fibers by Molecular Bases of Disease :

D. Eisenberg, M. Sawaya, M. Landau, 2014 .

Proteomics on full-length membrane proteins using mass spectrometry.

E. Wright, J. Whitelegge, H. Kaback, 2000, Biochemistry.

Multiple neurosteroid and cholesterol binding sites in voltage-dependent anion channel-1 determined by photo-affinity labeling.

María Queralt-Martín, Julian P Whitelegge, J. Whitelegge, 2019, Biochimica et biophysica acta. Molecular and cell biology of lipids.

Characterization of a recombinant molecule covalently indistinguishable from human cerebroside-sulfate activator protein (CSAct or Saposin B).

A. Waring, G. Privé, J. Whitelegge, 2003, Cellular and molecular biology.

Sequencing covalent modifications of membrane proteins.

J. Whitelegge, W. Cramer, J. Nishio, 2006, Journal of Experimental Botany.

The Photosystem II Assembly Factor Ycf48 from the Cyanobacterium Synechocystis sp. PCC 6803 Is Lipidated Using an Atypical Lipobox Sequence

J. Whitelegge, P. Halada, J. Komenda, 2021, International journal of molecular sciences.

p16 Protein and Gigaxonin Are Associated with the Ubiquitination of NFκB in Cisplatin-induced Senescence of Cancer Cells*

M. Fishbein, D. Elashoff, J. Whitelegge, 2014, The Journal of Biological Chemistry.

Structure of the asparagine-linked sugar chains of porcine kidney and human urine cerebroside sulfate activator protein.

J. Whitelegge, M. Kim, K. Faull, 2000, Journal of mass spectrometry : JMS.

Assembly of the Photosystem II Oxygen-evolving Complex Is Inhibited in psbA Site-directed Mutants of Chlamydomonas reinhardtii

J. Erickson, B. Diner, J. Whitelegge, 1995, The Journal of Biological Chemistry.

Site-Directed Mutagenesis of the Photosystem II D1 Gene and Transformation of the Chlamydomonas Chloroplast Genome

J. Erickson, J. Whitelegge, D. Koo, 1992 .

A Novel SET Domain Methyltransferase in Yeast

S. Clarke, J. Whitelegge, Tanya R. Porras-Yakushi, 2006, Journal of Biological Chemistry.

Mass spectrometry analysis of the photosystem II assembly factor Psb27 revealed variations in its lipid modification

J. Whitelegge, Jan Lambertz, M. Nowaczyk, 2021, Photosynthesis Research.

Profiling of integral membrane proteins and their post translational modifications using high-resolution mass spectrometry.

Puneet Souda, J. Whitelegge, W. Cramer, 2011, Methods.

Confident assignment of intact mass tags to human salivary cystatins using top-down Fourier-transform ion cyclotron resonance mass spectrometry

F. Halgand, D. Wong, J. Whitelegge, 2010, Journal of the American Society for Mass Spectrometry.

Characterization of the Outer Membrane Proteome of Leptospira interrogans Expressed during Acute Lethal Infection

J. Whitelegge, S. Bassilian, J. Nally, 2006, Infection and Immunity.

Comparative Proteomic Analysis of Differentially Expressed Proteins in the Urine of Reservoir Hosts of Leptospirosis

J. Whitelegge, J. Nally, P. Souda, 2011, PloS one.

A Novel SOD1 Intermediate Oligomer, Role of Free Thiols and Disulfide Exchange

J. Valentine, J. Whitelegge, E. B. Gralla, 2021, Frontiers in Neuroscience.

Drip, Ship, and Grip, then Slice and Dice: Comprehensive Stroke Center Management of Cervical and Intracranial Emboli

R. Jahan, J. Saver, J. Hinman, 2013, Front. Neurol..

Mitochondrial Dysfunction, Through Impaired Autophagy, Leads to Endoplasmic Reticulum Stress, Deregulated Lipid Metabolism, and Pancreatitis in Animal Models.

P. Hegyi, Z. Rakonczay, J. Whitelegge, 2017, Gastroenterology.

Peptide Composition of Stroke Causing Emboli Correlate with Serum Markers of Atherosclerosis and Inflammation

J. Gornbein, D. Liebeskind, L. Restrepo, 2017, Front. Neurol..

Defining intact protein primary structures from saliva: a step toward the human proteome project.

F. Halgand, D. Wong, J. Whitelegge, 2012, Analytical chemistry.

The flotillins are integral membrane proteins in lipid rafts that contain TCR-associated signaling components: implications for T-cell activation.

A. Nel, R. Effros, J. Whitelegge, 2003, Clinical immunology.

Identification of a unique Fe-S cluster binding site in a glycyl-radical type microcompartment shell protein.

T. Yeates, J. Jorda, M. Sawaya, 2014, Journal of molecular biology.

A protease-resistant Escherichia coli asparaginase with outstanding stability and enhanced anti-leukaemic activity in vitro

G. Colombo, M. Meli, J. Whitelegge, 2017, Scientific Reports.

Mass spectral analysis of the apolipoproteins on dog (Canis lupus familiaris) high density lipoproteins. Detection of apolipoprotein A-II.

F. Halgand, J. Whitelegge, S. Bassilian, 2008, Comparative biochemistry and physiology. Part D, Genomics & proteomics.

Mass spectral analysis of the apolipoproteins on mouse high density lipoproteins. Detection of post-translational modifications.

V. Schumaker, L. Castellani, J. Whitelegge, 2006, Biochimica et biophysica acta.

Micro-heterogeneity of human saliva peptide P-C characterized by high-resolution top-down fourier-transform mass spectrometry

F. Halgand, D. Wong, J. Whitelegge, 2010, Journal of the American Society for Mass Spectrometry.

Exposure of Solvent-Inaccessible Regions in the Amyloidogenic Protein Human SOD1 Determined by Hydroxyl Radical Footprinting

A. Waring, J. Valentine, J. Whitelegge, 2018, Journal of The American Society for Mass Spectrometry.

Taking charge of proteins from neurodegeneration to industrial biotechnology.

Bryan F. Shaw, J. Whitelegge, K. Faull, 2010, Advances in protein chemistry and structural biology.

Chapter 8 Intact Protein Mass Measurements and Top-Down Mass Spectrometry: Application to Integral Membrane Proteins

J. Whitelegge, 2008 .

Oxidative Damage to Proteins in Plants

J. Whitelegge, 1999 .

Adaptation to a high-tungsten environment: Pyrobaculum aerophilum contains an active tungsten nitrate reductase.

S. de Vries, J. Whitelegge, I. Schröder, 2010, Biochemistry.

Detection of two distinct forms of apoC-I in great apes.

X. Xiao, O. Ryder, J. Whitelegge, 2010, Comparative biochemistry and physiology. Part D, Genomics & proteomics.

Remodeling of the plasma membrane in preparation for sperm–egg recognition: roles of acrosomal proteins

R. Aitken, J. Whitelegge, N. Tanphaichitr, 2015, Asian journal of andrology.

Properties, metabolism and roles of sulfogalactosylglycerolipid in male reproduction.

J. Whitelegge, N. Tanphaichitr, F. Compostella, 2018, Progress in lipid research.

Helicobacter pylori infection impairs chaperone-assisted maturation of Na,K-ATPase in gastric epithelium.

B. Naini, J. Whitelegge, Y. Wen, 2020, American Journal of Physiology - Gastrointestinal and Liver Physiology.

Copper and Zinc Metallation Status of Copper-Zinc Superoxide Dismutase from Amyotrophic Lateral Sclerosis Transgenic Mice*

D. Borchelt, J. Valentine, J. Whitelegge, 2010, The Journal of Biological Chemistry.

Glucose transporter inhibitor-conjugated insulin mitigates hypoglycemia

J. Buse, J. Whitelegge, Zhen Gu, 2019, Proceedings of the National Academy of Sciences.

An extracellular disulfide bond forming protein (DsbF) from Mycobacterium tuberculosis: structural, biochemical, and gene expression analysis.

Soyeon Im, L. Hung, R. Riley, 2010, Journal of molecular biology.

Time‐Dependent Measurement of Nrf2‐Regulated Antioxidant Response to Ionizing Radiation Toward Identifying Potential Protein Biomarkers for Acute Radiation Injury

W. McBride, J. Whitelegge, Whitaker Cohn, 2019, Proteomics. Clinical applications.

Enhanced mitochondrial inhibition by 3,4‐dihydroxyphenyl‐acetaldehyde (DOPAL)‐oligomerized α‐synuclein

J. Whitelegge, Whitaker Cohn, J. B. Watson, 2019, Journal of neuroscience research.

Characterization of serum biomarkers for detection of early stage ovarian cancer

Kym Faull, Feng Su, Julian P Whitelegge, 2005, Proteomics.

Epithelial Junctions Depend on Intercellular Trans-interactions between the Na,K-ATPase β1 Subunits*

G. Sachs, J. Whitelegge, S. Bassilian, 2011, The Journal of Biological Chemistry.

Proteome analysis of lipid rafts in Jurkat cells characterizes a raft subset that is involved in NF-kappaB activation.

A. Nel, J. Whitelegge, P. Bickel, 2004, Journal of proteome research.

DUSP7 regulates the activity of ERK2 to promote proper chromosome alignment during cell division

R. Damoiseaux, J. Whitelegge, A. Gholkar, 2020, bioRxiv.

Ethanol Induced Disordering of Pancreatic Acinar Cell Endoplasmic Reticulum: An ER Stress/Defective Unfolded Protein Response Model

S. Sakkiah, Wei Yang, M. Freeman, 2018, Cellular and molecular gastroenterology and hepatology.

Diminished viability of human ovarian cancer cells by antigen-specific delivery of carbon monoxide with a family of photoactivatable antibody-photoCORM conjugates

J. Whitelegge, P. Mascharak, C. Janzen, 2019, Chemical science.

Feedback modulation of cholesterol metabolism by the lipid-responsive non-coding RNA LeXis.

D. Casero, J. Whitelegge, Marius C. Jones, 2016 .

Identification of a novel phosphorylation site in c-jun directly targeted in vitro by protein kinase D.

J. Whitelegge, E. Rozengurt, R. Waldron, 2007, Biochemical and biophysical research communications.

Amide bonds assemble pili on the surface of bacilli

L. Marraffini, J. Whitelegge, O. Schneewind, 2008, Proceedings of the National Academy of Sciences.

Identification of Immunologically Relevant Proteins of Chlamydophila abortus Using Sera from Experimentally Infected Pregnant Ewes

J. Whitelegge, J. Nally, P. Souda, 2010, Clinical and Vaccine Immunology.

Insights into the structure and molecular topography of the fatty acylated domain of synaptotagmin-1.

A. Waring, J. Whitelegge, C. Gundersen, 2019, Biochimica et biophysica acta. Biomembranes.

Current status of the multinational Arabidopsis community

G. Krouk, G. Coruzzi, G. Mendel, 2020, Plant direct.

Metal-free Superoxide Dismutase-1 and Three Different Amyotrophic Lateral Sclerosis Variants Share a Similar Partially Unfolded β-Barrel at Physiological Temperature*

Bryan F. Shaw, A. Nersissian, J. Valentine, 2009, The Journal of Biological Chemistry.

The Structure and Interactions of Periplasmic Domains of Crucial MmpL Membrane Proteins from Mycobacterium tuberculosis.

Yuqi Liu, N. Chim, C. Goulding, 2015, Chemistry & biology.

Characterization of the Endothelial Cell Cytoskeleton following HLA Class I Ligation

Mary E. Ziegler, E. Reed, J. Whitelegge, 2012, PloS one.

Distinctive features of the D101N and D101G variants of superoxide dismutase 1; two mutations that produce rapidly progressing motor neuron disease

Jacob I. Ayers, D. Borchelt, J. Valentine, 2014, Journal of neurochemistry.

Modulation of mutant superoxide dismutase 1 aggregation by co‐expression of wild‐type enzyme

D. Borchelt, J. Whitelegge, A. Durazo, 2009, Journal of neurochemistry.

A novel variant of human superoxide dismutase 1 harboring amyotrophic lateral sclerosis‐associated and experimental mutations in metal‐binding residues and free cysteines lacks toxicity in vivo

D. Borchelt, J. Valentine, J. Whitelegge, 2012, Journal of neurochemistry.

Tctex1d2 associates with short-rib polydactyly syndrome proteins and is required for ciliogenesis

J. Whitelegge, P. Jackson, Y. Lo, 2015, Cell cycle.

and is required for ciliogenesis.

J. Whitelegge, P. Jackson, Y. Lo, 2015 .

N-terminal acetylation of annexin A2 is required for S100A10 binding

H. Luecke, J. Whitelegge, G. Ozorowski, 2012, Biological chemistry.

Integrated Multiomics Analysis of Salivary Exosomes to Identify Biomarkers Associated with Changes in Mood States and Fatigue

B. Teter, G. Cole, D. Elashoff, 2022, International journal of molecular sciences.

Intramolecular amide bonds stabilize pili on the surface of bacilli

Chuan He, J. Whitelegge, O. Schneewind, 2009, Proceedings of the National Academy of Sciences.

Identificationof Proteins Associated with Murine Gammaherpesvirus68Virions

J. Stewart, R. Sun, Z. Zhou, 2003, Journal of Virology.

Identification of Proteins Associated with Murine Gammaherpesvirus 68 Virions

J. Stewart, R. Sun, J. Whitelegge, 2003 .

Mass spectral measurements of the apoHDL in horse (Equus caballus) cerebrospinal fluid.

J. Whitelegge, S. Bassilian, P. Souda, 2012, Comparative biochemistry and physiology. Part D, Genomics & proteomics.

Rhizobium common nod genes are required for biofilm formation

J. Whitelegge, A. Hirsch, K. Faull, 2008, Molecular microbiology.

inhibitors promote hematopoietic stem cell regeneration.

R. Damoiseaux, J. Whitelegge, Martina Roos, 2019 .

Dissection of mechanistic principles of a secondary multidrug efflux protein.

J. Whitelegge, C. Ryan, E. Bibi, 2012, Molecular cell.

The X-Linked-Intellectual-Disability-Associated Ubiquitin Ligase Mid2 Interacts with Astrin and Regulates Astrin Levels to Promote Cell Division.

J. Whitelegge, Y. Lo, A. Gholkar, 2016, Cell reports.

The Mid2 X-linked Intellectual Disability Ubiquitin Ligase Associates with Astrin and Regulates Astrin Levels to Promote Cell Division

J. Whitelegge, Y. Lo, A. Gholkar, 2016 .

Expression, purification, crystallization, and preliminary X-ray analysis of recombinant human saposin B.

G. Privé, J. Whitelegge, K. Faull, 2003, Protein expression and purification.

Up Close with Membrane Lipid-Protein Complexes

J. Whitelegge, 2011, Science.

Evidence that YycJ is a novel 5'-3' double-stranded DNA exonuclease acting in Bacillus anthracis mismatch repair.

Upendra K. Kar, J. Hoch, Jeffrey H. Miller, 2013, DNA repair.

Integrating mass spectrometry into membrane protein drug discovery.

J. Whitelegge, H. Kaback, A. Weinglass, 2004, Current opinion in drug discovery & development.

Molecular characterization of Vibrio parahaemolyticus vSGLT: a model for sodium-coupled sugar cotransporters.

E. Wright, G. Zampighi, J. Whitelegge, 2000, The Journal of biological chemistry.

PYY(1-36) is the major form of PYY in rat distal small intestine: Quantification using high-resolution mass spectrometry

D. Keire, J. Whitelegge, S. Bassilian, 2010, Regulatory Peptides.

A new endogenous form of PYY isolated from canine ileum: Gly-extended PYY(1-36)

D. Keire, J. Whitelegge, S. Bassilian, 2008, Regulatory Peptides.

Mass spectral analysis of pig (Sus scrofa) apo HDL: Identification of pig apoA-II, a dimeric apolipoprotein.

V. Schumaker, J. Whitelegge, D. L. Puppione, 2005, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Sequence of horse (Equus caballus) apoA-II. Another example of a dimer forming apolipoprotein.

V. Schumaker, J. Whitelegge, W. Fischer, 2004, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Synthesis of novel [14C]‐labelled phenylureas bearing photoactive azido and diazirine groups as photoaffinity labels for the herbicide binding site of photosystem two

J. Whitelegge, P. Camilleri, J. Bowyer, 1993 .

Proteomic Characterization of Pig Sperm Anterior Head Plasma Membrane Reveals Roles of Acrosomal Proteins in ZP3 Binding

R. Aitken, J. Whitelegge, N. Tanphaichitr, 2015, Journal of cellular physiology.

Dissection of the Spindle Assembly Checkpoint by Proximity Proteomics

J. Whitelegge, A. Gholkar, Erick F. Velasquez, 2020, bioRxiv.

Isolation and Characterization of a Novel Xanthophyll-rich Pigment-protein complex from Spinach.

J. Whitelegge, Jianxin Zhu, S. M. Gómez, 1998 .

ATM protein purified from vaccinia virus expression system: DNA binding requirements for kinase activation.

D. Rawlings, R. Gatti, J. Whitelegge, 2004, Biochemical and biophysical research communications.

Comparative lipid binding study on the cerebroside sulfate activator (saposin B)

J. Whitelegge, K. Faull, A. Fluharty, 2001, Journal of neuroscience research.

Lysine acetylation can generate highly charged enzymes with increased resistance toward irreversible inactivation

George M Whitesides, Bryan F. Shaw, John M Neveu, 2008, Protein science : a publication of the Protein Society.

Amyloid seeding of transthyretin by ex vivo cardiac fibrils and its inhibition

D. Eisenberg, M. Benson, J. Whitelegge, 2018, Proceedings of the National Academy of Sciences.

10 Covalent Modification of Photosystem II Reaction Center Polypeptides

J. Whitelegge, 2005 .

Mapping of a copper-binding site on the small CP12 chloroplastic protein of Chlamydomonas reinhardtii using top-down mass spectrometry and site-directed mutagenesis.

F. Halgand, J. Erales, J. Whitelegge, 2009, The Biochemical journal.

Gas-phase structure of the E. coli OmpA dimer.

J. Whitelegge, 2014, Structure.

Efficient light harvesting in a dark, hot, acidic environment: the structure and function of PSI-LHCI from Galdieria sulphuraria.

P. Fromme, J. Whitelegge, E. Boekema, 2011, Biophysical journal.

CLSTN3β enforces adipocyte multilocularity to facilitate lipid utilization

Pradeep S Rajendran, D. Black, J. Wohlschlegel, 2022, Nature.

Cardiovascular‐related proteins identified in human plasma by the HUPO Plasma Proteome Project Pilot Phase

Peipei Ping, Chenggong Zong, P. Ping, 2005, Proteomics.

Lipid-conjugated Smac analogues.

A. Waring, W. McBride, J. Whitelegge, 2015, Bioorganic & medicinal chemistry letters.

Classes of Drugs that Mitigate Radiation Syndromes

R. Damoiseaux, K. Iwamoto, W. McBride, 2021, Frontiers in Pharmacology.

Full Subunit Coverage Liquid Chromatography Electrospray Ionization Mass Spectrometry (LCMS+) of an Oligomeric Membrane Protein

J. Whitelegge, Ross M. Taylor, W. Cramer, 2002, Molecular & Cellular Proteomics.

Ferredoxin:NADP+ oxidoreductase is a subunit of the chloroplast cytochrome b6f complex.

J. Whitelegge, W. Cramer, H. Zhang, 2001, The Journal of biological chemistry.

Plant peptides and peptidomics.

J. Brusslan, J. Whitelegge, N. Farrokhi, 2008, Plant biotechnology journal.

Phenotypic and proteomic characterization of treponemes associated with bovine digital dermatitis.

J. Whitelegge, D. Alt, J. Nally, 2019, Veterinary microbiology.

Hydroponics on a chip: analysis of the Fe deficient Arabidopsis thylakoid membrane proteome.

J. Whitelegge, J. Nishio, S. M. Gómez, 2009, Journal of proteomics.

Conservation of lipid functions in cytochrome bc complexes.

E. Yamashita, J. Whitelegge, W. Cramer, 2011, Journal of molecular biology.

Transit Peptide Cleavage Sites of Integral Thylakoid Membrane Proteins*

J. Whitelegge, J. Nishio, K. Faull, 2003, Molecular & Cellular Proteomics.

Top-down mass spectrometry of integral membrane proteins

F. Halgand, J. Whitelegge, V. Zabrouskov, 2006, Expert review of proteomics.

The minimum information about a proteomics experiment (MIAPE)

Lennart Martens, Chris F. Taylor, John R Yates, 2007, Nature Biotechnology.

The cell wall and secretory proteome of a tobacco cell line synthesising secondary wall

J. Whitelegge, M. Rossignol, A. Boudet, 2009, Proteomics.

Thylakoid membrane proteomics

J. Whitelegge, 2004, Photosynthesis Research.

Methionine oxidation within the cerebroside‐sulfate activator protein (CSAct or Saposin B)

A. Waring, J. Whitelegge, M. Sherman, 2000, Protein science : a publication of the Protein Society.

A Membrane Receptor for Retinol Binding Protein Mediates Cellular Uptake of Vitamin A

P. Ping, D. Bok, R. Kawaguchi, 2007, Science.

Mammalian Protein Arginine Methyltransferase 7 (PRMT7) Specifically Targets RXR Sites in Lysine- and Arginine-rich Regions*

S. Clarke, A. Clark, J. Masson, 2013, The Journal of Biological Chemistry.

Mass spectrometry (LC-MS/MS) identified proteomic biosignatures of breast cancer in proximal fluid.

R. Saxton, Jianbo He, J. Whitelegge, 2012, Journal of proteome research.

Structural biology workflow for the expression and characterization of functional human sodium glucose transporter type 1 in Pichia pastoris

J. Whitelegge, J. Cladera, A. Alcaraz, 2019, Scientific Reports.

Amniotic and allantoic fluids from experimentally infected sheep contain immunoglobulin specific for Chlamydophila abortus.

J. Whitelegge, J. Nally, B. Markey, 2011, Veterinary immunology and immunopathology.

Identification of the molecular chaperone alpha B‐crystallin in demineralized bone powder and osteoblast‐like cells

J. Whitelegge, S. Murray, K. Behnam, 2002, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

The proteomes of human parotid and submandibular/sublingual gland salivas collected as the ductal secretions.

John R Yates, Tao Xu, Daniel Cociorva, 2008, Journal of proteome research.

A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells

Y. Gwack, S. Srikanth, J. Whitelegge, 2010, Nature Cell Biology.

Mass spectral analyses of the two major apolipoproteins of great ape high density lipoproteins.

O. Ryder, J. Whitelegge, S. Bassilian, 2009, Comparative biochemistry and physiology. Part D, Genomics & proteomics.

1-(4-nitrobenzenesulfonyl)-4-penylpiperazine increases the number of Peyer's patch-associated regenerating crypts in the small intestines after radiation injury.

R. Damoiseaux, W. McBride, J. Whitelegge, 2019, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

ATR inhibition facilitates targeting of leukemia dependence on convergent nucleotide biosynthetic pathways

A. Ribas, J. Czernin, Woosuk Kim, 2017, Nature Communications.

Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence

Giovanni Coppola, Thomas M. Vondriska, Julian P. Whitelegge, 2017, Neuron.

Non-repair Pathways for Minimizing Protein Isoaspartyl Damage in the Yeast Saccharomyces cerevisiae*

S. Clarke, J. Whitelegge, A. Patananan, 2014, The Journal of Biological Chemistry.

J-domain protein CDJ2 and HSP70B are a plastidic chaperone pair that interacts with vesicle-inducing protein in plastids 1.

J. Whitelegge, Bettina Knapp, M. Schroda, 2005, Molecular biology of the cell.

The chloroplastic GrpE homolog of Chlamydomonas: two isoforms generated by differential splicing.

J. Whitelegge, F. Wollman, M. Schroda, 2001, The Plant cell.

Molecular Dissection of Novel Trafficking and Processing of the Toxoplasma gondii Rhoptry Metalloprotease Toxolysin‐1

J. Whitelegge, P. Bradley, J. Dubremetz, 2012, Traffic.

Proteogenomic review of the changes in primate apoC-I during evolution

J. Whitelegge, D. L. Puppione, 2013, Frontiers in Biology.

Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA

Brandon J Thomas, A. Lusis, S. Smale, 2018, Nature Medicine.

Feedback modulation of cholesterol metabolism by LeXis, a lipid-responsive non-coding RNA

Richard G. Lee, D. Casero, J. Whitelegge, 2016, Nature.

Hepatic lipase maturation: a partial proteome of interacting factors This work was supported by the Cedars-Sinai Medical Center, the Department of Veterans Affairs, and Grant HL-24841 from the National Institutes of Health. Published, JLR Papers in Press, January 8, 2009.

J. Whitelegge, S. Bassilian, H. Wong, 2009, Journal of Lipid Research.

RNA-binding protein PSPC1 promotes the differentiation-dependent nuclear export of adipocyte RNAs

D. Black, S. Young, S. Mandrup, 2017, The Journal of clinical investigation.

Stimulation of synaptoneurosome glutamate release by monomeric and fibrillated α‐synuclein

J. Whitelegge, J. B. Watson, B. Koo, 2017, Journal of neuroscience research.

First sequencing of ancient coral skeletal proteins

D. Jacobs, J. Whitelegge, Jeana L. Drake, 2020, Scientific Reports.

Exercise affects energy metabolism and neural plasticity‐related proteins in the hippocampus as revealed by proteomic analysis

F. Gomez-Pinilla, J. Whitelegge, S. Vaynman, 2006, The European journal of neuroscience.

Identities of Sequestered Proteins in Aggregates from Cells with Induced Polyglutamine Expression

F. Gage, S. Suhr, J. Whitelegge, 2001, The Journal of cell biology.

Proteomics of Bronchoalveolar Lavage Fluid Reveals a Lung Oxidative Stress Response in Murine Herpesvirus-68 Infection

R. Sun, Ting-Ting Wu, J. Whitelegge, 2018, Viruses.

1 Proteomics of bronchoalveolar lavage fluid reveals a 2 lung oxidative stress response in murine herpesvirus-3 68 infection . 4 5

R. Sun, Ting-Ting Wu, J. Whitelegge, 2018 .

Structure-Function, Stability, and Chemical Modification of the Cyanobacterial Cytochrome b6f Complex from Nostoc sp. PCC 7120*

E. Yamashita, J. Whitelegge, W. Cramer, 2009, Journal of Biological Chemistry.

Purification and proteomic analysis of outer membrane vesicles from a clinical isolate of Leptospira interrogans serovar Copenhageni

J. Whitelegge, J. Nally, D. R. Blanco, 2005, Proteomics.

Integral membrane proteins and bilayer proteomics.

Julian P Whitelegge, J. Whitelegge, 2013, Analytical chemistry.

High CO2 Leads to Na,K-ATPase Endocytosis via c-Jun Amino-Terminal Kinase-Induced LMO7b Phosphorylation

Yosef Gruenbaum, Julian P. Whitelegge, István Vadász, 2015, Molecular and Cellular Biology.

Dissociation Strategies to Maximize Coverage of α-Helical Domains in Top-Down Mass Spectrometry of Integral Membrane Proteins.

J. Whitelegge, V. Zabrouskov, R. Huguet, 2021, Journal of the American Society for Mass Spectrometry.

A protease-resistant Escherichia coli asparaginase with outstanding stability and enhanced anti-leukaemic activity in vitro

G. Colombo, M. Meli, J. Whitelegge, 2017, Scientific Reports.

A Monoclonal Antibody That Conveys In Vitro Killing and Partial Protection in Experimental Syphilis Binds a Phosphorylcholine Surface Epitope of Treponema pallidum

D. L. Cox, J. Whitelegge, K. Faull, 2005, Infection and Immunity.

Combined Phosphoproteomics and Bioinformatics Strategy in Deciphering Drug Resistant Related Pathways in Triple Negative Breast Cancer

J. Whitelegge, P. Souda, Huan-Ming Hsu, 2014, International journal of proteomics.

A two component chitin‐binding protein from French bean – association of a proline‐rich protein with a cysteine‐rich polypeptide

J. Whitelegge, L. Bindschedler, D. Millar, 2006, FEBS letters.

PTPσ inhibitors promote hematopoietic stem cell regeneration

R. Damoiseaux, W. McBride, J. Whitelegge, 2019, Nature Communications.

Proteomics. Making sense of genomic information for drug discovery.

J. Whitelegge, J. le Coutre, 2001, American journal of pharmacogenomics : genomics-related research in drug development and clinical practice.

Biomarkers to Predict Antidepressant Response

S. Horvath, S. Nelson, A. Toga, 2010, Current psychiatry reports.

Septin Dynamics Are Essential for Exocytosis*

G. Sachs, J. Whitelegge, L. Dada, 2015, The Journal of Biological Chemistry.

The Aftermath of Surviving Acute Radiation Hematopoietic Syndrome and its Mitigation

G. Cheng, J. Sayre, R. Damoiseaux, 2019, Radiation Research.

A Novel 3-Methylhistidine Modification of Yeast Ribosomal Protein Rpl3 Is Dependent upon the YIL110W Methyltransferase*

S. Clarke, J. Whitelegge, Kristofor J. Webb, 2010, The Journal of Biological Chemistry.

A Peroxidase-Dependent Apoplastic Oxidative Burst in Cultured Arabidopsis Cells Functions in MAMP-Elicited Defense1[W][OA]

F. Ausubel, P. Finch, J. Whitelegge, 2012, Plant Physiology.

NdhP and NdhQ: two novel small subunits of the cyanobacterial NDH-1 complex.

J. Whitelegge, W. Cramer, P. Souda, 2011, Biochemistry.

Withaferin A binds covalently to the N-terminal domain of annexin A2

H. Luecke, J. Whitelegge, G. Ozorowski, 2012, Biological chemistry.

Uncovering the Mechanism of Aggregation of Human Transthyretin

Duilio Cascio, Roland Riek, Lin Jiang, 2015, The Journal of Biological Chemistry.

Identification of Two SET Domain Proteins Required for Methylation of Lysine Residues in Yeast Ribosomal Protein Rpl42ab*

S. Clarke, J. Whitelegge, Kristofor J. Webb, 2008, Journal of Biological Chemistry.

A Novel SET Domain Methyltransferase Modifies Ribosomal Protein Rpl23ab in Yeast*

T. Miranda, S. Clarke, J. Whitelegge, 2005, Journal of Biological Chemistry.

Identification of protein N-terminal methyltransferases in yeast and humans.

S. Clarke, J. Whitelegge, Kristofor J. Webb, 2010, Biochemistry.

Structure of the toxic core of α-synuclein from invisible crystals

Nicholas K. Sauter, Sébastien Boutet, E. L. Guenther, 2015, Nature.

Initiation and elongation in fibrillation of ALS-linked superoxide dismutase

Julian P. Whitelegge, Armando Durazo, J. Valentine, 2008, Proceedings of the National Academy of Sciences.

Phenotypic and Genomic Analysis of Hypervirulent Human-associated Bordetella bronchiseptica

J. Parkhill, Jeff F. Miller, S. Tomida, 2012, BMC Microbiology.

The mitochondrial inner membrane protein Mitofilin exists as a complex with SAM50, metaxins 1 and 2, coiled‐coil‐helix coiled‐coil‐helix domain‐containing protein 3 and 6 and DnaJC11

J. Xie, J. Whitelegge, R. Capaldi, 2007, FEBS letters.

Formation of Amyloid Fibers by Monomeric Light Chain Variable Domains*

D. Eisenberg, M. Sawaya, M. Landau, 2014, The Journal of Biological Chemistry.

Toward the bilayer proteome, electrospray ionization-mass spectrometry of large, intact transmembrane proteins.

J. Lee, G. Privé, J. Whitelegge, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Intrinsic membrane association of Drosophila cysteine string proteins

J. Whitelegge, S. Kohan, C. Gundersen, 1998, FEBS letters.

Electrospray‐ionization mass spectrometry of intact intrinsic membrane proteins

J. Whitelegge, C. Gundersen, K. Faull, 1998, Protein science : a publication of the Protein Society.

Sequence analysis of photoaffinity-labelled peptides derived by proteolysis of photosystem-2 reaction centres from thylakoid membranes treated with [14C]azidoatrazine.

J. Whitelegge, P. Camilleri, J. Bowyer, 1992, European journal of biochemistry.

Rpe65 Isomerase Associates with Membranes through an Electrostatic Interaction with Acidic Phospholipid Headgroups*

J. Whitelegge, S. Bassilian, J. Kaylor, 2009, The Journal of Biological Chemistry.

Emulation of the structure of the Saposin protein fold by a lung surfactant peptide construct of surfactant Protein B

F. Walther, A. Waring, J. Whitelegge, 2022, PloS one.

Best practices and benchmarks for intact protein analysis for top-down mass spectrometry

Lloyd M Smith, Ljiljana Paša-Tolić, Ying Ge, 2019, Nature Methods.

Crystal structure of saposin B reveals a dimeric shell for lipid binding

G. Privé, J. Whitelegge, K. Faull, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Plant proteomics: blasting out of a MudPIT

J. Whitelegge, 2002, Proceedings of the National Academy of Sciences of the United States of America.

4-(Nitrophenylsulfonyl)piperazines mitigate radiation damage to multiple tissues

G. Cheng, J. Sayre, R. Damoiseaux, 2017, PLoS ONE.

Analysis of enzyme kinetics using electrospray ionization mass spectrometry and multiple reaction monitoring: fucosyltransferase V.

J. Whitelegge, T. Toyokuni, K. Faull, 2001, Biochemistry.

Proteomics and Mass Spectrometry for Cancer Biomarker Discovery

R. Saxton, D. Shen, Jianbo He, 2007, Biomarker insights.

Septin oligomerization regulates persistent expression of ErbB2/HER2 in gastric cancer cells.

G. Sachs, J. Whitelegge, D. Scott, 2016, The Biochemical journal.

Proteomic-Based Biosignatures in Breast Cancer Classification and Prediction of Therapeutic Response

R. Saxton, D. Shen, Jianbo He, 2011, International Journal of Proteomics.

Identification of Differentially Expressed Proteins in Murine Embryonic and Postnatal Cortical Neural Progenitors

D. Geschwind, H. Kornblum, J. Whitelegge, 2010, PloS one.

Revealing the Dynamics of the 20 S Proteasome Phosphoproteome

P. Ping, Haojie Lu, Peng-Yuan Yang, 2008, Molecular & Cellular Proteomics.

D. Borchelt, J. Valentine, J. Whitelegge, 2013, Proceedings of the National Academy of Sciences.

Translation Control of Swarming Proficiency in Bacillus subtilis by 5-Amino-pentanolylated Elongation Factor P*

Sarah B Erickson, Philip R. Gafken, M. Ibba, 2016, The Journal of Biological Chemistry.

COI1-dependent jasmonate signalling affects growth, metabolite production and cell wall protein composition in arabidopsis

P. Finch, J. Whitelegge, J. O’Brien, 2018, Annals of botany.

Quantitative Measure of Intestinal Permeability Using Blue Food Coloring.

A. Zarrinpar, J. Whitelegge, S. Duarte, 2019, The Journal of surgical research.

The impact of exercise on mitochondrial dynamics and the role of Drp1 in exercise performance and training adaptations in skeletal muscle

A. Hevener, C. Drevon, A. Lusis, 2018, Molecular metabolism.

Small lipidated anti-obesity compounds derived from neuromedin U.

A. Waring, W. McBride, J. Whitelegge, 2015, European journal of medicinal chemistry.

Cysteine string protein β is prominently associated with nerve terminals and secretory organelles in mouse brain

J. Whitelegge, S. Kohan, C. Gundersen, 2010, Brain Research.

Yeast Ribosomal/Cytochrome c SET Domain Methyltransferase Subfamily

S. Clarke, J. Whitelegge, Tanya R. Porras-Yakushi, 2007, Journal of Biological Chemistry.

Mass spectrometry (LC-MS/MS) site-mapping of N-glycosylated membrane proteins for breast cancer biomarkers.

R. Saxton, Jianbo He, J. Whitelegge, 2009, Journal of proteome research.

Preliminary Characterization of Extracellular Vesicles From Auditory HEI-OC1 Cells

J. Whitelegge, K. Faull, Whitaker Cohn, 2019 .

Mass spectrometry for high throughput quantitative proteomics in plant research: lessons from thylakoid membranes.

Julian P Whitelegge, J. Whitelegge, 2004, Plant physiology and biochemistry : PPB.

Proteomics of membrane proteins.

J. Whitelegge, K. Faull, S. M. Gómez, 2003, Advances in protein chemistry.

The Chloroplast Grana Proteome Defined by Intact Mass Measurements from Liquid Chromatography Mass Spectrometry*

J. Whitelegge, J. Nishio, K. Faull, 2002, Molecular & Cellular Proteomics.

Hydrophobic Fractionation Enhances Novel Protein Detection by Mass Spectrometry in Triple Negative Breast Cancer.

R. Saxton, Jianbo He, J. Whitelegge, 2010, Journal of proteomics & bioinformatics.

Tumor proteomic profiling predicts the susceptibility of breast cancer to chemotherapy.

R. Saxton, D. Shen, Jianbo He, 2009, International journal of oncology.

Proteomic strategies to elucidate pathogenic mechanisms of spirochetes

J. A. Carroll, J. Whitelegge, J. Nally, 2007, Proteomics. Clinical applications.

Structural Studies of the Sputnik Virophage

M. Rossmann, D. Raoult, B. La Scola, 2009, Journal of Virology.

Differential Association of Hemoglobin with Proinflammatory High Density Lipoproteins in Atherogenic/Hyperlipidemic Mice

J. Liao, Katherine J Chou, S. Reddy, 2007, Journal of Biological Chemistry.

Integral membrane proteins: bottom-up, top-down and structural proteomics

Upendra K. Kar, J. Whitelegge, U. Kar, 2017, Expert review of proteomics.

Impairment of Mitochondria in Adult Mouse Brain Overexpressing Predominantly Full-Length, N-Terminally Acetylated Human α-Synuclein

Upendra K. Kar, G. Mathern, E. Masliah, 2013, PloS one.

Proteomic profiling of cancer biomarkers.

Julian P Whitelegge, J. Gornbein, J. Whitelegge, 2003, Briefings in functional genomics & proteomics.

Mass spectrometric measurements of the apolipoproteins of bovine (Bos taurus) HDL.

J. Whitelegge, S. Bassilian, C. Nebbia, 2012, Comparative biochemistry and physiology. Part D, Genomics & proteomics.

Mass spectral analysis of domestic and wild equine apoA-I and A-II: detection of unique dimeric forms of apoA-II.

V. Schumaker, J. Whitelegge, S. Bassilian, 2005, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Discovery and characterization of a unique mycobacterial heme acquisition system

Angelina Iniguez, Nicholas Chim, Julian P Whitelegge, 2011, Proceedings of the National Academy of Sciences.

Novel role for Na,K-ATPase in phosphatidylinositol 3-kinase signaling and suppression of cell motility.

A. Rajasekaran, J. Whitelegge, Yi Zheng, 2005, Molecular biology of the cell.

Targeting a Subset of the Membrane Proteome for Top–Down Mass Spectrometry: Introducing the Proteolipidome

J. Whitelegge, 2020, Proteomes.

The novel gene EG-1 stimulates cellular proliferation.

J. Whitelegge, Ming Lu, A. Norris, 2005, Cancer research.

Proteomic Analysis of the Mammalian Katanin Family of Microtubule-severing Enzymes Defines Katanin p80 subunit B-like 1 (KATNBL1) as a Regulator of Mammalian Katanin Microtubule-severing

J. Whitelegge, A. Gholkar, S. Senese, 2016, Molecular & Cellular Proteomics.

Isolation and identification of cytoskeleton-associated prolamine mRNA binding proteins from developing rice seeds

T. Okita, J. Whitelegge, Naoko Crofts, 2010, Planta.

Photoaffinity labeling with cholesterol analogues precisely maps a cholesterol-binding site in voltage-dependent anion channel-1

Julian P. Whitelegge, J. Janetka, J. Whitelegge, 2017, The Journal of Biological Chemistry.

Modest stabilization by most hydrogen-bonded side-chain interactions in membrane proteins

Virgil L. Woods, J. Bowie, S. Faham, 2008, Nature.

Net Protein Breakdown, and Increased IL-6 Release Placebo-Controlled, Bilaterally Infused Human Leg: Increased Insulin Sensitivity, Increased on Local Fuel Metabolism and Cytokine Levels in the

G. Sachs, K. Ryan, J. Whitelegge, 2015 .

SOD1 aggregation and ALS: role of metallation states and disulfide status.

J. Valentine, J. Whitelegge, Joan Selverstone Valentine, 2013, Current topics in medicinal chemistry.

Physiological and evolutionary implications of tetrameric photosystem I in cyanobacteria

M. Li, J. Whitelegge, E. Boekema, 2019, Nature Plants.

Age‐induced mitochondrial DNA point mutations are inadequate to alter metabolic homeostasis in response to nutrient challenge

A. Hevener, J. Whitelegge, L. Stiles, 2020, Aging cell.

The S-layer biogenesis system of Synechocystis 6803: Role of Sll1180 and Sll1181 (E. coli HlyB and HlyD analogs) as type-I secretion components for Sll1951 export.

J. Whitelegge, Rachna Agarwal, S. Saini, 2018, Biochimica et biophysica acta. Biomembranes.

Extracellular Vesicles From Auditory Cells as Nanocarriers for Anti-inflammatory Drugs and Pro-resolving Mediators

J. Whitelegge, K. Faull, Whitaker Cohn, 2019, Front. Cell. Neurosci..

Detergent-insoluble Aggregates Associated with Amyotrophic Lateral Sclerosis in Transgenic Mice Contain Primarily Full-length, Unmodified Superoxide Dismutase-1*

Bryan F. Shaw, D. Borchelt, A. Nersissian, 2008, Journal of Biological Chemistry.

Local Unfolding in a Destabilized, Pathogenic Variant of Superoxide Dismutase 1 Observed with H/D Exchange and Mass Spectrometry*

Bryan F. Shaw, A. Nersissian, J. Valentine, 2006, Journal of Biological Chemistry.

Type V Collagen in Scar Tissue Regulates the Size of Scar after Heart Injury

S. Ahadian, A. Khademhosseini, M. Pellegrini, 2020, Cell.

Ketones block amyloid entry and improve cognition in an Alzheimer's model

D. Eisenberg, E. Reiman, J. Whitelegge, 2016, Neurobiology of Aging.

Quantitative Proteomics Using Formalin-fixed, Paraffin-embedded Biopsy Tissues in Inflammatory Disease

I. Lopez, D. Elashoff, J. Whitelegge, 2019, Journal of proteomics & bioinformatics.

Mapping the cofilin binding site on yeast G-actin by chemical cross-linking.

D. Sept, F. Halgand, J. Whitelegge, 2008, Journal of molecular biology.

Proteomics Analysis of Brain Meningiomas in Pursuit of Novel Biomarkers of the Aggressive Behavior.

J. Whitelegge, D. Kelly, G. Barkhoudarian, 2016, Journal of proteomics & bioinformatics.

Carboxyl-terminal processing of the D1 protein and photoactivation of water-splitting in photosystem II. Partial purification and characterization of the processing enzyme from Scenedesmus obliquus and Pisum sativum.

J. Whitelegge, J. Bowyer, M. Taylor, 1992, The Journal of biological chemistry.

Regulation of Iron Homeostasis Through Parkin-mediated Lactoferrin Ubiquitylation

J. Whitelegge, Stefan Schmollinger, Y. Lo, 2020, bioRxiv.

Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females

A. Hevener, K. Korach, E. Stefani, 2016, Science Translational Medicine.

Mae inhibits Pointed‐P2 transcriptional activity by blocking its MAPK docking site

James U Bowie, Feng Qiao, Haiyun Song, 2006, The EMBO journal.

Anthrax Lethal Toxin Induced Lysosomal Membrane Permeabilization and Cytosolic Cathepsin Release Is Nlrp1b/Nalp1b-Dependent

T. Muir, J. Whitelegge, S. Bassilian, 2009, PloS one.

Intact protein mass spectrometry and top-down proteomics

J. Whitelegge, 2013, Expert review of proteomics.

Role of domain swapping in the hetero-oligomeric cytochrome b6f lipoprotein complex.

J. Whitelegge, J. Stofleth, W. Cramer, 2015, Biochemistry.

The Murine Cardiac 26S Proteasome: An Organelle Awaiting Exploration

P. Ping, T. Vondriska, A. Gomes, 2005, Annals of the New York Academy of Sciences.

Hydrophobic Proteome Analysis of Triple Negative and Hormone-Receptor-Positive-Her2-Negative Breast Cancer by Mass Spectrometer

R. Saxton, Jianbo He, J. Whitelegge, 2010, Clinical Proteomics.

Full Membrane Protein Coverage Digestion and Quantitative Bottom-Up Mass Spectrometry Proteomics.

J. Whitelegge, Joseph R. Capri, 2017, Methods in molecular biology.

Phospho-Network Analysis Identifies and Quantifies Hepatitis C Virus (HCV)-induced Hepatocellular Carcinoma (HCC) Proteins Regulating Viral-mediated Tumor Growth.

Roger Williams, J. Whitelegge, Darshil Patel, 2016, Cancer genomics & proteomics.

A novel mass spectrometric assay for the cerebroside sulfate activator protein (saposin B) and arylsulfatase A Published, JLR Papers in Press, August 1, 2005. DOI 10.1194/jlr.M500188-JLR200

G. Privé, J. Whitelegge, F. Compostella, 2005, Journal of Lipid Research.

ATR inhibition facilitates targeting of leukemia dependence on convergent nucleotide biosynthetic pathways

A. Ribas, J. Czernin, Woosuk Kim, 2017, Nature Communications.

Temporal Analysis of the Antigenic Composition of Borrelia burgdorferi during Infection in Rabbit Skin

J. Whitelegge, T. Crother, C. Champion, 2004, Infection and Immunity.

Elevated sleep need in a stress-resilient Drosophila species

Jeffrey M. Donlea, Sara M. Wasserman, J. Whitelegge, 2023, bioRxiv.

Membrane proteins in four acts: function precedes structure determination.

S. Zakharov, E. Yamashita, J. Rochet, 2011, Methods.

Cyclic Rhamnosylated Elongation Factor P Establishes Antibiotic Resistance in Pseudomonas aeruginosa

Julian P. Whitelegge, Kym F. Faull, Sarah B Erickson, 2015, mBio.

Structure–function of cyanobacterial outer‐membrane protein, Slr1270: Homolog of Escherichia coli drug export/colicin import protein, TolC

S. Zakharov, J. Whitelegge, W. Cramer, 2014, FEBS letters.

The Disulfide Bond, but Not Zinc or Dimerization, Controls Initiation and Seeded Growth in Amyotrophic Lateral Sclerosis-linked Cu,Zn Superoxide Dismutase (SOD1) Fibrillation*

J. Valentine, J. Whitelegge, E. B. Gralla, 2015, The Journal of Biological Chemistry.

Data‐directed top‐down Fourier‐transform mass spectrometry of a large integral membrane protein complex: Photosystem II from Galdieria sulphuraria

P. Fromme, A. Weber, J. Whitelegge, 2010, Proteomics.

Exploring the Role of a Unique Carboxyl Residue in EmrE by Mass Spectrometry*

J. Whitelegge, H. Kaback, S. Schuldiner, 2005, Journal of Biological Chemistry.

HSP70 Copurifies with Zika Virus Particles.

A. Dasgupta, J. Whitelegge, Ronik Khachatoorian, 2018, Virology.

Trans-membrane Signaling in Photosynthetic State Transitions

S. Zakharov, J. Whitelegge, S. Singh, 2016, The Journal of Biological Chemistry.

Relationship between mutant Cu/Zn superoxide dismutase 1 maturation and inclusion formation in cell models

Jacob I. Ayers, D. Borchelt, J. Valentine, 2017, Journal of neurochemistry.

Murine Gammaherpesvirus 68 ORF52 Encodes a Tegument Protein Required for Virion Morphogenesis in the Cytoplasm

R. Sun, Z. Zhou, Ting-Ting Wu, 2007, Journal of Virology.

DIGITAL MICROFLUIDIC CHIPS FOR AUTOMATED HYDROGEN DEUTERIUM EXCHANGE (HDX) MS ANALYSIS

J. Whitelegge, Cheng-guo Shen, K. Faull, 2011 .

Improved Zebra Finch Brain Transcriptome identifies novel proteins with sex differences.

X. Xiao, S. White, Ting Fu, 2022, Gene.

Recruitment of septin cytoskeletal proteins by botulinum toxin A protease determines its remarkable stability

George Sachs, Julian P Whitelegge, Puneet Souda, 2014, Journal of Cell Science.

Post-translational Modifications of Integral Membrane Proteins Resolved by Top-down Fourier Transform Mass Spectrometry with Collisionally Activated Dissociation*

J. Bowie, P. Ping, J. Whitelegge, 2010, Molecular & Cellular Proteomics.

Mass Spectrometry of the Subunits of Highly Active Cytochrome b6f Complex from Spinach and the Cyanobacterium, M. laminosus: Identification of PetA,B,C,D,G,L,M,N Subunits in both Complexes and FNR in the Spinach b6f Complex

J. Whitelegge, W. Cramer, Huamin Zhang, 2001 .

J. Bowie, J. Whitelegge, Duan Yang, 2009, Journal of the American Chemical Society.

A novel SET domain methyltransferase in yeast: Rkm2-dependent trimethylation of ribosomal protein L12ab at the N terminus. VOLUME 281 (2006) PAGES 35835-35845

S. Clarke, J. Whitelegge, Tanya R. Porras-Yakushi, 2008 .

Diminished viability of human ovarian cancer cells by antigen-speci ﬁ c delivery of carbon monoxide with a family of photoactivatable antibody-photoCORM conjugates † EDGE ARTICLE

J. Whitelegge, P. Mascharak, Whitaker Cohn, 2019 .

Plasmin‐mediated proteolysis of human factor IXa in the presence of calcium/phospholipid: Conversion of procoagulant factor IXa to a fibrinolytic enhancer

K. Vadivel, J. Whitelegge, S. P. Bajaj, 2020, Journal of thrombosis and haemostasis : JTH.

Ferredoxin:NADP+ Oxidoreductase, is a Subunit of the Cytochrome b6f Complex of Spinach Chloroplasts: Implications for the Pathway of Cyclic Electron Transport

J. Whitelegge, W. Cramer, Huamin Zhang, 2001 .

Mapping Proximity Associations of Core Spindle Assembly Checkpoint Proteins

J. Whitelegge, A. Gholkar, Erick F. Velasquez, 2021, Journal of proteome research.

Interactions between Partner Switcher Orthologs BtrW and BtrV Regulate Type III Secretion in Bordetella

Jeff F. Miller, J. Whitelegge, S. Mattoo, 2005, Journal of bacteriology.

Structural biology workflow for the expression and characterization of functional human sodium glucose transporter type 1 in Pichia pastoris

J. Whitelegge, J. Cladera, A. Alcaraz, 2019, Scientific Reports.

Subtle modification of isotope ratio proteomics; an integrated strategy for expression proteomics.

Jonathan E Katz, Julian P Whitelegge, J. Katz, 2004, Phytochemistry.

Elucidation of substrate binding interactions in a membrane transport protein by mass spectrometry

J. Whitelegge, H. Kaback, K. Faull, 2003, The EMBO journal.

Demonstration by Mass Spectrometry that Purified Native Treponema pallidum Rare Outer Membrane Protein 1 (Tromp1) Has a Cleaved Signal Peptide

J. Whitelegge, D. R. Blanco, James N. Miller, 1999, Journal of bacteriology.

HPLC and Mass Spectrometry of Integral Membrane Proteins

J. Whitelegge, 2009 .

HPLC and mass spectrometry of intrinsic membrane proteins.

Julian P Whitelegge, J. Whitelegge, 2004, Methods in molecular biology.

Investigation of the Effect of Protein Oxidation Upon the Lipid-Binding Activity of the Cerebroside-Sulfate Activator Protein (Saposin B)

A. Waring, J. Whitelegge, K. Faull, 1998 .

BCN057, a Modulator of GSK3β, Induces KRAS G12D Mutant Pancreatic Cancer Cell Death

W. McBride, J. Whitelegge, Adrian Gomez, 2021, bioRxiv.

Naked Mole-Rat, a Rodent with an Apolipoprotein A-I Dimer.

J. Whitelegge, R. Buffenstein, S. Charugundla, 2020, Lipids.

Detection of breast cancer biomarkers in nipple aspirate fluid by SELDI-TOF and their identification by combined liquid chromatography-tandem mass spectrometry.

D. Shen, Jianbo He, J. Gornbein, 2007, International journal of oncology.

Mass spectrometry (LC-MS/MS) analysis of proximal fluid and cell membrane proteins for breast cancer biomarkers

R. Saxton, Jianbo He, J. Whitelegge, 2008 .

Biomarkers detected by proteomic analysis predicts breast cancer response to neoadjuvant chemotherapy.

D. Shen, J. Gornbein, J. Whitelegge, 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Therapy of autoimmune inflammation in sporadic amyotrophic lateral sclerosis: Dimethyl fumarate and H‐151 downregulate inflammatory cytokines in the cGAS‐STING pathway

S. Hwang, J. Whitelegge, B. Hammock, 2023, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Revealing the Dynamics of the 20 S Proteasome Phosphoproteome

P. Ping, Haojie Lu, Peng-Yuan Yang, 2008, Molecular & Cellular Proteomics.

The impact of exercise on mitochondrial dynamics and the role of Drp1 in exercise performance and training adaptations in skeletal muscle

A. Hevener, C. Drevon, A. Lusis, 2018, Molecular metabolism.

Ketones block amyloid entry and improve cognition in an Alzheimer's model

D. Eisenberg, E. Reiman, J. Whitelegge, 2016, Neurobiology of Aging.

Metal-free Superoxide Dismutase-1 and Three Different Amyotrophic Lateral Sclerosis Variants Share a Similar Partially Unfolded β-Barrel at Physiological Temperature*

Bryan F. Shaw, A. Nersissian, J. Valentine, 2009, The Journal of Biological Chemistry.

Investigation of Anti-SOD1 Antibodies Yields New Structural Insight into SOD1 Misfolding and Surprising Behavior of the Antibodies Themselves.

G. Bitan, J. Whitelegge, N. Cashman, 2018, ACS chemical biology.

Inhibition kinetics of carba- and C-fucosyl analogues of GDP-fucose against fucosyltransferase V: implication for the reaction mechanism.

J. Whitelegge, T. Toyokuni, K. Faull, 2004, Bioorganic & medicinal chemistry letters.

Molecular Characterization of Vibrio parahaemolyticusvSGLT

G. Zampighi, J. Whitelegge, S. Eskandari, 2000, The Journal of Biological Chemistry.

Taking charge of proteins from neurodegeneration to industrial biotechnology.

Bryan F. Shaw, J. Whitelegge, K. Faull, 2010, Advances in protein chemistry and structural biology.

A single C-terminal residue controls SARS-CoV-2 spike trafficking and virion assembly

Yanan He, J. Orban, B. Pierce, 2023, bioRxiv.

Confident assignment of intact mass tags to human salivary cystatins using top-down Fourier-transform ion cyclotron resonance mass spectrometry

F. Halgand, D. Wong, J. Whitelegge, 2010, Journal of the American Society for Mass Spectrometry.

J. Bowie, J. Whitelegge, Duan Yang, 2009, Journal of the American Chemical Society.

Structure–function of cyanobacterial outer‐membrane protein, Slr1270: Homolog of Escherichia coli drug export/colicin import protein, TolC

S. Zakharov, J. Whitelegge, W. Cramer, 2014, FEBS letters.

Tandem mass spectrometry of integral membrane proteins for top-down proteomics

J. Whitelegge, 2005 .

increased resistance toward irreversible inactivation Lysine acetylation can generate highly charged enzymes with data

Bryan F. Shaw, G. Whitesides, William Arbuthnot Sir Lane, 2022 .