D. Heinz

发表

Response of a protein structure to cavity-creating mutations and its relation to the hydrophobic effect.

B. Matthews, W. Baase, A. Eriksson, 1992, Science.

Plasmin(ogen)-binding alpha-enolase from Streptococcus pneumoniae: crystal structure and evaluation of plasmin(ogen)-binding sites.

Wolf-Dieter Schubert, Dirk W Heinz, D. Heinz, 2004, Journal of molecular biology.

In situ structural analysis of the Yersinia enterocolitica injectisome

J. Kowal, H. Stahlberg, D. Heinz, 2013, eLife.

Targeting DnaN for tuberculosis therapy using novel griselimycins

H. Matter, D. Heinz, R. Müller, 2015, Science.

Databases and ontologies BRAGI : linking and visualization of database information in a 3 D viewer and modeling tool

D. Schomburg, D. Heinz, J. Reichelt, 2005 .

Streamlining Homogeneous Glycoprotein Production for Biophysical and Structural Applications by Targeted Cell Line Development

R. Owens, M. Gossen, K. Büssow, 2011, PloS one.

ActA from Listeria monocytogenes Can Interact with Up to Four Ena/VASP Homology 1 Domains Simultaneously* 210

J. Wehland, C. Urbanke, D. Heinz, 2001, The Journal of Biological Chemistry.

Crystallization and preliminary X-ray analysis of the EVH1 domain of Vesl-2b.

J. Wehland, D. Heinz, W. Schubert, 2000, Acta crystallographica. Section D, Biological crystallography.

Energetic cost and structural consequences of burying a hydroxyl group within the core of a protein determined from Ala-->Ser and Val-->Thr substitutions in T4 lysozyme.

B. Matthews, M. Blaber, D. Heinz, 1993, Biochemistry.

A phosphatidic acid-binding protein is important for lipid homeostasis and adaptation to anaerobic biofilm conditions in Pseudomonas aeruginosa.

D. Jahn, D. Heinz, F. Narberhaus, 2018, The Biochemical journal.

Aromatic amino acids at the surface of InlB are essential for host cell invasion by Listeria monocytogenes

J. Wehland, E. Gherardi, D. Heinz, 2003, Molecular microbiology.

Crystal Structure of the Nitrogenase-like Dark Operative Protochlorophyllide Oxidoreductase Catalytic Complex (ChlN/ChlB)2*♦

D. Jahn, D. Heinz, W. Schubert, 2010, The Journal of Biological Chemistry.

Dimerization of the plant molybdenum insertase Cnx1E is required for synthesis of the molybdenum cofactor.

D. Schafflick, D. Heinz, R. Mendel, 2017, The Biochemical journal.

Engineered variants of InlB with an additional leucine‐rich repeat discriminate between physiologically relevant and packing contacts in crystal structures of the InlB:MET complex

E. Gherardi, D. Heinz, H. Niemann, 2012, Protein science : a publication of the Protein Society.

Braces for the peptide backbone: insights into structure-activity relationships of protease inhibitor mimics with locked amide conformations.

D. Heinz, H. Kolmar, O. Avrutina, 2012, Angewandte Chemie.

ATP-driven Reduction by Dark-operative Protochlorophyllide Oxidoreductase from Chlorobium tepidum Mechanistically Resembles Nitrogenase Catalysis*

D. Jahn, D. Heinz, W. Schubert, 2008, Journal of Biological Chemistry.

PHOSPHATIDYLINOSITOL-SPECIFIC PHOSPHOLIPASE C

M. T. Ryan, D. Heinz, T. Bullock, 1996 .

Structural Analysis of Bacterial and Viral Infections and a Cysteine Proteinase Legumain

T. Pietschmann, D. Jahn, D. Heinz, 2014 .

Secrets of a secretin.

D. Heinz, 2013, Structure.

ATP-driven Reduction by Dark-operative Protochlorophyllide Oxidoreductase from Mechanistically Resembles Nitrogenase Catalysis

D. Jahn, D. Heinz, W. Schubert, 2008 .

Much anticipated--the bioactive conformation of epothilone and its binding to tubulin.

D. Heinz, W. Schubert, G. Höfle, 2005, Angewandte Chemie.

The crystal structure of siroheme decarboxylase in complex with iron-uroporphyrin III reveals two essential histidine residues.

D. Heinz, H. Arai, S. Schmelz, 2014, Journal of molecular biology.

Refined crystal structures of subtilisin novo in complex with wild-type and two mutant eglins. Comparison with other serine proteinase inhibitor complexes.

K. Wilson, M. Grütter, J. Priestle, 1991, Journal of molecular biology.

Biosynthesis of 5-Aminolevulinic Acid

D. Jahn, D. Heinz, 2009 .

Crystal Structure of the Heme d1 Biosynthesis Enzyme NirE in Complex with Its Substrate Reveals New Insights into the Catalytic Mechanism of S-Adenosyl-l-methionine-dependent Uroporphyrinogen III Methyltransferases*

D. Heinz, G. Layer, J. Krausze, 2011, The Journal of Biological Chemistry.

Structural characterization of Spinacia oleracea trypsin inhibitor III (SOTI-III).

A. Christmann, D. Heinz, H. Kolmar, 2013, Acta crystallographica. Section D, Biological crystallography.

The Substrate Radical of Escherichia coli Oxygen-independent Coproporphyrinogen III Oxidase HemN*

D. Jahn, D. Heinz, M. Trost, 2006, Journal of Biological Chemistry.

Escherichia coli Glutamyl-tRNA Reductase

H. Inokuchi, D. Söll, L. Randau, 2002, The Journal of Biological Chemistry.

How amino-acid insertions are allowed in an α-helix of T4 lysozyme

Dirk W. Heinz, Brian W. Matthews, Frederick W. Dahlquist, 1993, Nature.

Structural and functional comparison of HemN to other radical SAM enzymes

D. Jahn, D. Heinz, W. Schubert, 2005, Biological chemistry.

The oxygen-independent coproporphyrinogen III oxidase HemN utilizes harderoporphyrinogen as a reaction intermediate during conversion of coproporphyrinogen III to protoporphyrinogen IX

H. Schiebel, D. Heinz, T. Dülcks, 2010, Biological chemistry.

Glutamate recognition and hydride transfer by Escherichia coli glutamyl‐tRNA reductase

D. Jahn, D. Heinz, W. Schubert, 2007, The FEBS journal.

Structure of ADP-aluminium fluoride-stabilized protochlorophyllide oxidoreductase complex

C. Lange, D. Jahn, D. Heinz, 2013, Proceedings of the National Academy of Sciences.

Structure and function of enzymes in heme biosynthesis

Dieter Jahn, Joachim Reichelt, Dirk W Heinz, 2010, Protein science : a publication of the Protein Society.

Structure of the type III secretion recognition protein YscU from Yersinia enterocolitica.

D. Heinz, G. Cornelis, J. van den Heuvel, 2009, Journal of molecular biology.

Crystal structure of Yersinia enterocolitica type III secretion chaperone SycT

D. Heinz, G. Cornelis, H. Niemann, 2005, Protein science : a publication of the Protein Society.

Crystal structure of the phosphatidylinositol-specific phospholipase C from the human pathogen Listeria monocytogenes.

J. Wehland, D. Heinz, T. Chakraborty, 1997, Journal of molecular biology.

Crystal structure of 5‐aminolevulinate synthase, the first enzyme of heme biosynthesis, and its link to XLSA in humans

Dieter Jahn, Wolf-Dieter Schubert, Dirk W Heinz, 2005, The EMBO journal.

Biomacromolecular Interactions, Assemblies and Machines: A Structural View

M. Weiss, D. Heinz, K. Wendt, 2006, Chembiochem : a European journal of chemical biology.

Crystal Structure and Catalytic Mechanism of 4-Methylmuconolactone Methylisomerase*

D. Heinz, D. Pieper, M. Marín, 2009, The Journal of Biological Chemistry.

The crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa, defines a third class of sulfatases

B. Tümmler, D. Heinz, W. Schubert, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Structure and function of radical SAM enzymes.

Dieter Jahn, Wolf-Dieter Schubert, Dirk W Heinz, 2004, Current opinion in chemical biology.

Crystal structure of coproporphyrinogen III oxidase reveals cofactor geometry of Radical SAM enzymes

D. Jahn, D. Heinz, W. Schubert, 2003, The EMBO journal.

Structure of the Yersinia enterocolitica type III secretion translocator chaperone SycD.

D. Heinz, G. Cornelis, H. Niemann, 2007, Journal of molecular biology.

Extending the Host Range of Listeria monocytogenes by Rational Protein Design

A. Gruber, A. Lengeling, D. Heinz, 2007, Cell.

Structural and mechanistic comparison of prokaryotic and eukaryotic phosphoinositide-specific phospholipases C.

R. Williams, D. Heinz, L. Essen, 1998, Journal of molecular biology.

Crystal structure of a non-discriminating glutamyl-tRNA synthetase.

D. Jahn, D. Heinz, W. Schubert, 2006, Journal of molecular biology.

Complex Formation between Glutamyl-tRNA Reductase and Glutamate-1-semialdehyde 2,1-Aminomutase in Escherichia coli during the Initial Reactions of Porphyrin Biosynthesis*

Dieter Jahn, Stefan Schauer, Wolf-Dieter Schubert, 2005, Journal of Biological Chemistry.

Structure of Internalin, a Major Invasion Protein of Listeria monocytogenes, in Complex with Its Human Receptor E-Cadherin

J. Wehland, C. Urbanke, D. Heinz, 2002, Cell.

Crystallization of human leukocyte elastase with its inhibitor Pro44-eglin c.

M. Grütter, D. Heinz, M. Liersch, 1989, Journal of molecular biology.

New Inhibitory Properties of Eglin C after Specific Mutagenesis

M. Grütter, D. Heinz, M. Liersch, 1989 .

Structural Aspects of Adhesion to and Invasion of Host Cells by the Human Pathogen Listeria monocytogenes

D. Heinz, W. Schubert, 2003, Chembiochem : a European journal of chemical biology.

1 1 STRUCTURE OF THE HUMAN RECEPTOR TYROSINE KINASE MET IN COMPLEX WITH THE LISTERIA MONOCYTOGENES INVASION PROTEIN INLB

E. Gherardi, P. Butler, D. Heinz, 2009 .

Structure of the Human Receptor Tyrosine Kinase Met in Complex with the Listeria Invasion Protein InlB

E. Gherardi, P. Butler, D. Heinz, 2007, Cell.

Probing the active site of Pseudomonas aeruginosa porphobilinogen synthase using newly developed inhibitors.

D. Heinz, M. Nentwich, R. Neier, 2006, Biochemistry.

Evolutionary relationship between initial enzymes of tetrapyrrole biosynthesis.

D. Jahn, D. Heinz, W. Schubert, 2006, Journal of molecular biology.

Tracking the evolution of porphobilinogen synthase metal dependence in vitro.

D. Jahn, D. Heinz, W. Schubert, 2005, Journal of molecular biology.

Structures of the nucleotide-binding domain of the human ABCB6 transporter and its complexes with nucleotides.

D. Jahn, D. Heinz, M. Haffke, 2010, Acta crystallographica. Section D, Biological crystallography.

High Affinity Peptide Inhibitors of the Hepatitis C Virus NS3-4A Protease Refractory to Common Resistant Mutants

T. Pietschmann, D. Heinz, J. van den Heuvel, 2012, The Journal of Biological Chemistry.

The Phosphotyrosine Peptide Binding Specificity of Nck1 and Nck2 Src Homology 2 Domains*

Dirk W. Heinz, Wolf-Dieter Schubert, T. Stradal, 2006, Journal of Biological Chemistry.

Arranged sevenfold: structural insights into the C-terminal oligomerization domain of human C4b-binding protein.

Matteo Dal Peraro, Stefan Schmelz, Andrea Scrima, 2013, Journal of molecular biology.

Polysaccharide Synthesis of the Levansucrase SacB from Bacillus megaterium Is Controlled by Distinct Surface Motifs*

D. Jahn, D. Heinz, J. Seibel, 2011, The Journal of Biological Chemistry.

Crystal structure of the electron transfer complex rubredoxin–rubredoxin reductase of Pseudomonas aeruginosa

B. Tümmler, D. Heinz, W. Schubert, 2007, Proceedings of the National Academy of Sciences.

Crystal structure and standardized geometric analysis of InlJ, a listerial virulence factor and leucine-rich repeat protein with a novel cysteine ladder.

P. Cossart, D. Heinz, W. Schubert, 2008, Journal of molecular biology.

Structural basis for autoinhibition and activation of Auto, a virulence‐associated peptidoglycan hydrolase of Listeria monocytogenes

D. Heinz, W. Schubert, M. Nimtz, 2009, Molecular microbiology.

The N-terminal domain of Homer/Vesl is a new class II EVH1 domain.

J. Wehland, D. Heinz, R. Frank, 2001, Journal of molecular biology.

Structure of Shigella IpgB2 in Complex with Human RhoA

K. Rottner, T. Stradal, D. Heinz, 2010, The Journal of Biological Chemistry.

Protein structural plasticity exemplified by insertion and deletion mutants in T4 lysozyme

B. Matthews, W. Baase, I. Vetter, 1996, Protein science : a publication of the Protein Society.

Folding and function of a T4 lysozyme containing 10 consecutive alanines illustrate the redundancy of information in an amino acid sequence.

B. Matthews, W. Baase, D. Heinz, 1992, Proceedings of the National Academy of Sciences of the United States of America.

How amino-acid insertions are allowed in an alpha-helix of T4 lysozyme.

B. Matthews, W. Baase, F. Dahlquist, 1993, Nature.

Dissection of protein structure and folding by directed mutagenesis.

U. Sauer, B. Matthews, W. Baase, 1992, Faraday discussions.

Changing the inhibitory specificity and function of the proteinase inhibitor eglin c by site-directed mutagenesis: functional and structural investigation.

Jeffrey W. Peng, S. Hyberts, G. Wagner, 1992, Biochemistry.

Adhesins and invasins of pathogenic bacteria: a structural view.

D. Heinz, W. Schubert, H. Niemann, 2004, Microbes and infection.

Probing the roles of active site residues in phosphatidylinositol-specific phospholipase C from Bacillus cereus by site-directed mutagenesis.

D. Heinz, C. Gässler, M. Ryan, 1997, Biochemistry.

Crystal structure of phosphatidylinositol-specific phospholipase C from Bacillus cereus in complex with glucosaminyl(alpha 1-->6)-D-myo-inositol, an essential fragment of GPI anchors.

L. Weaver, D. Heinz, J. Keana, 1996, Biochemistry.

Structural basis for complex formation between human IRSp53 and the translocated intimin receptor Tir of enterohemorrhagic E. coli.

K. Büssow, T. Stradal, D. Heinz, 2011, Structure.

X-ray and neutron small-angle scattering analysis of the complex formed by the Met receptor and the Listeria monocytogenes invasion protein InlB.

Dmitri I Svergun, Maxim V Petoukhov, Martine Moulin, 2008, Journal of molecular biology.

“Plug and Play”-expression systems for high-quality production of recombinant proteins for structural analysis

D. Heinz, J. Heuvel, 2002 .

"Plug and Play" -expression systems for

D. Heinz, 2002 .

V‐shaped structure of glutamyl‐tRNA reductase, the first enzyme of tRNA‐dependent tetrapyrrole biosynthesis

D. Jahn, D. Heinz, W. Schubert, 2001, The EMBO journal.

Unusual carbon fixation gives rise to diverse polyketide extender units.

D. Heinz, R. Müller, S. Rachid, 2011, Nature chemical biology.

Proteins in Motion

D. Heinz, W. Schubert, 2005 .

Structural Basis for Intrinsic Thermosensing by the Master Virulence Regulator RovA of Yersinia*

D. Heinz, C. Ritter, P. Dersch, 2012, The Journal of Biological Chemistry.

The absolute configuration of rhizopodin and its inhibition of actin polymerization by dimerization.

Gregor Hagelueken, Rolf Jansen, Wolf-Dieter Schubert, 2009, Angewandte Chemie.

Structure of the effector-binding domain of the LysR-type transcription factor RovM from Yersinia pseudotuberculosis.

D. Heinz, P. Dersch, N. Quade, 2011, Acta crystallographica. Section D, Biological crystallography.

Classification : Biophysics Thermodynamically Re-engineering the Listerial Invasion Complex InlA / E-Cadherin

D. Heinz, W. Schubert, T. Wollert, 2008 .

Thermodynamically reengineering the listerial invasion complex InlA/E-cadherin

D. Heinz, W. Schubert, T. Wollert, 2007, Proceedings of the National Academy of Sciences.

Transfer RNA-Dependent Aminolevulinic Acid Formation: Structure and Function Of Glutamyl-tRNA Synthetase, Reductase and Glutamate-1-Semialdehyde-2,1-Aminomutase

D. Jahn, D. Heinz, W. Schubert, 2006 .

Crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa.

D. Heinz, W. Schubert, H. Kolmar, 2006 .

The mutation G145S in PrfA, a key virulence regulator of Listeria monocytogenes, increases DNA‐binding affinity by stabilizing the HTH motif

Wolf-Dieter Schubert, Dirk W Heinz, D. Heinz, 2005, Molecular microbiology.

Crystal structure of the phosphatidylinositol‐specific phospholipase C from Bacillus cereus in complex with myo‐inositol.

D. Heinz, T. Bullock, M. Ryan, 1995, The EMBO journal.

Internalins from the human pathogen Listeria monocytogenes combine three distinct folds into a contiguous internalin domain.

J. Wehland, D. Heinz, W. Schubert, 2001, Journal of molecular biology.

Structure and function of glutamyl-tRNA reductase, the first enzyme of tetrapyrrole biosynthesis in plants and prokaryotes

D. Jahn, D. Heinz, W. Schubert, 2004, Photosynthesis Research.

Structures of two bacterial resistance factors mediating tRNA-dependent aminoacylation of phosphatidylglycerol with lysine or alanine

D. Jahn, D. Heinz, J. Moser, 2015, Proceedings of the National Academy of Sciences.

Ligand-mediated dimerization of the Met receptor tyrosine kinase by the bacterial invasion protein InlB.

E. Gherardi, D. Heinz, H. Niemann, 2010, Journal of molecular biology.

Virulence of Agrobacterium tumefaciens requires lipid homeostasis mediated by the lysyl‐phosphatidylglycerol hydrolase AcvB

D. Jahn, D. Heinz, Meriyem Aktas, 2018, Molecular microbiology.

Crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa, in complex with 1-decane-sulfonic-acid.

D. Heinz, W. Schubert, H. Kolmar, 2006 .

Structures and diseases

Manfred S Weiss, Patrick Cramer, K Ulrich Wendt, 2008, Nature Structural &Molecular Biology.

Author response: In situ structural analysis of the Yersinia enterocolitica injectisome

J. Kowal, H. Stahlberg, D. Heinz, 2013 .

Much Anticipated — The Bioactive Conformation of Epothilone and Its Binding to Tubulin

D. Heinz, W. Schubert, G. Hoefle, 2005 .

Highlight: Of Systems and Structures

C. Betzel, M. Wilmanns, D. Heinz, 2010, Biological chemistry.

Rapid crystallization of T4 lysozyme by intermolecular disulfide cross-linking.

B. Matthews, D. Heinz, B W Matthews, 1994, Protein engineering.

Folding and stability of the leucine-rich repeat domain of internalin B from Listeri monocytogenes.

R. Seckler, D. Heinz, W. Pfeil, 2004, Journal of molecular biology.

Ligand-mediated dimerization of the Met receptor tyrosine kinase by the bacterial invasion protein InlB.

E. Gherardi, D. Heinz, H. Niemann, 2010, Journal of molecular biology.

X-ray and neutron small-angle scattering analysis of the complex formed by the Met receptor and the Listeria monocytogenes invasion protein InlB.

D. Svergun, E. Gherardi, M. Petoukhov, 2008, Journal of molecular biology.

Crystal structure of 5‐aminolevulinate synthase, the first enzyme of heme biosynthesis, and its link to XLSA in humans

D. Jahn, D. Heinz, W. Schubert, 2005, The EMBO journal.

Wound healing potential of a dimeric InlB variant analyzed by in vitro experiments on re-epithelialization of human skin models.

D. Heinz, H. Niemann, C. Müller-Goymann, 2014, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.