Lei Zhang

发表

Large-scale assignment of N-glycosylation sites using complementary enzymatic deglycosylation.

Lei Zhang, Wei Zhang, Pengyuan Yang, 2011, Talanta.

SAPT, a Fast and Efficient Approach for Simultaneous Profiling of Protein N- and C-Terminome.

Haojie Lu, Lei Zhang, Zhongjie Wang, 2021, Analytical chemistry.

Functional lipidomics: Palmitic acid impairs hepatocellular carcinoma development by modulating membrane fluidity and glucose metabolism

Pengyuan Yang, Lei Zhang, G. Yan, 2017, Hepatology.

HST-MRM-MS: A Novel High-Sample-Throughput Multiple Reaction Monitoring Mass Spectrometric Method for Multiplex Absolute Quantitation of Hepatocellular Carcinoma Serum Biomarker.

Haojie Lu, Lei Zhang, Liqi Xie, 2018, Journal of proteome research.

N-Glycosylation pattern of recombinant human CD82 (KAI1), a tumor-associated membrane protein.

Wei Zhang, Pengyuan Yang, Hong Wang, 2012, Journal of proteomics.

In-Depth Analysis of C Terminomes Based on LysC Digestion and Site-Selective Dimethylation.

Haojie Lu, Caiyun Fang, Lei Zhang, 2019, Analytical chemistry.

Positive enrichment of C-terminal peptides using oxazolone chemistry and biotinylation.

Haojie Lu, Caiyun Fang, Pengyuan Yang, 2015, Analytical chemistry.

Multilayered N-glycoproteomics reveals impaired N-glycosylation promoting Alzheimer’s disease

Pengyuan Yang, Lei Zhang, Jun Yao, 2019, bioRxiv.

In-depth mapping of the mouse brain N-glycoproteome reveals widespread N-glycosylation of diverse brain proteins

Peng-Yuan Yang, Lei Zhang, Jun Yao, 2016, Oncotarget.

Quantification of Intact O-Glycopeptides on Haptoglobin in Sera of Patients With Hepatocellular Carcinoma and Liver Cirrhosis

Lei Zhang, Limin Li, G. Yan, 2021, Frontiers in Chemistry.

Nascent Glycoproteome Reveals That N-Linked Glycosylation Inhibitor-1 Suppresses Expression of Glycosylated Lysosome-Associated Membrane Protein-2

Haojie Lu, Lei Zhang, Jun Yao, 2022, Frontiers in Molecular Biosciences.

A Rapid and Easy Enrichment Strategy for Naturally Acetylated N Termini Based on LysN Digestion and Amine-reactive Resin Capture.

Haojie Lu, Caiyun Fang, Lei Zhang, 2020, Analytical chemistry.

Specific and Reversible Enrichment of Early-Stage Glycated Proteome Based on Thiazolidine Chemistry and Palladium-Mediated Cleavage.

Haojie Lu, Caiyun Fang, Lei Zhang, 2022, Analytical chemistry.

ITMSQ: A software tool for N‐ and C‐terminal fragment ion pairs based isobaric tandem mass spectrometry quantification

Yang Zhang, Peng-Yuan Yang, Hao-Jie Lu, 2015, Proteomics.

Regulation of Cardiac-Specific Proteins Expression by Moderate-Intensity Aerobic Exercise Training in Mice With Myocardial Infarction Induced Heart Failure Using MS-Based Proteomics

Lei Zhang, J. Ge, A. Sun, 2021, Frontiers in Cardiovascular Medicine.

In vivo termini amino acid labeling for quantitative proteomics.

Peng-Yuan Yang, Hao-Jie Lu, Lei Zhang, 2011, Analytical chemistry.

Fast and precise quantification of serum biomarkers and simultaneous recognition of multiple diseases enabled by a stable isotope-labelled peptides assisted high-throughput MRM strategy.

Pengyuan Yang, Lei Zhang, Anqi Hu, 2020, The Analyst.

Relative Quantification of N-Glycopeptide Sialic Acid Linkage Isomers by Ion Mobility Mass Spectrometry.

Haojie Lu, Lei Zhang, Shu Zhang, 2021, Analytical chemistry.

iTRAQ-2DLC-ESI-MS/MS based identification of a new set of immunohistochemical biomarkers for classification of dysplastic nodules and small hepatocellular carcinoma.

Pengyuan Yang, Yan Li, Yin-kun Liu, 2011, Journal of proteome research.

Nascent Proteome and Glycoproteome Reveal the Inhibition Role of ALG1 in Hepatocellular Carcinoma Cell Migration

Haojie Lu, Lei Zhang, Jun Yao, 2022, Phenomics.

Site-Specific Quantification of Protein Ubiquitination on MS2 Fragment Ion Level via Isobaric Peptide Labeling.

Haojie Lu, Caiyun Fang, Lei Zhang, 2017, Analytical chemistry.

Rapid sample preparation workflow based on enzymatic nanoreactors for potential serum biomarker discovery in pancreatic cancer.

Pengyuan Yang, Lei Zhang, Yuning Wang, 2021, Talanta.

Identification of potential serum biomarkers of acute paraquat poisoning in humans using an iTRAQ quantitative proteomic

Pengyuan Yang, Lei Zhang, Ling Lin, 2018, RSC advances.

Diagnosis of thymic epithelial tumor subtypes by a quantitative proteomic approach.

Haojie Lu, Lei Zhang, Gang Chen, 2018, The Analyst.

Fluorous Solid-Phase Extraction Technique Based on Nanographite Fluoride.

Haojie Lu, Cheng Zhang, Lei Zhang, 2017, Analytical chemistry.

Puromycin-Modified Silica Microsphere-Based Nascent Proteomics Method for Rapid and Deep Nascent Proteome Profile.

Pengyuan Yang, Lei Zhang, Jun Yao, 2021, Analytical chemistry.

Site-Specific Quantification of Protein Palmitoylation by Cysteine-Stable Isotope Metabolic Labeling.

Haojie Lu, Caiyun Fang, Lei Zhang, 2018, Analytical chemistry.

O-GlcNAcylation of MEK2 promotes the proliferation and migration of breast cancer cells.

Haojie Lu, Lei Zhang, Yuanyuan Ruan, 2020, Glycobiology.

Highly Selective and Large Scale Mass Spectrometric Analysis of 4-Hydroxynonenal Modification via Fluorous Derivatization and Fluorous Solid-Phase Extraction.

Haojie Lu, Lei Zhang, Jun Yao, 2017, Analytical chemistry.

Peptide- and Protein-Level Combined Strategy for Analyzing Newly Synthesized Proteins by Integrating Tandem Orthogonal Proteolysis with Cleavable Bioorthogonal Tagging.

Haojie Lu, Lei Zhang, Huimin Bao, 2022, Analytical chemistry.

Ribosome 18S m6A Methyltransferase METTL5 Promotes Translation Initiation and Breast Cancer Cell Growth.

J. Han, Lei Zhang, F. Lan, 2020, Cell reports.

Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer

Fei Lan, Yiming Li, Jia Fan, 2018, Nature.

A primary role of TET proteins in establishment and maintenance of De Novo bivalency at CpG islands

Lei Zhang, F. Lan, Duan Ma, 2016, Nucleic acids research.

Ultradeep Palmitoylomics Enabled by Dithiodipyridine-Functionalized Magnetic Nanoparticles.

Y. Zhang, Haojie Lu, Caiyun Fang, 2018, Analytical chemistry.

Precision N-Glycoproteomic Profiling of Murine Peritoneal Macrophages After Different Stimulations

Pengyuan Yang, Lei Zhang, Ling Lin, 2021, Frontiers in Immunology.

Multilayered N-glycoproteome profiling reveals highly heterogeneous and dysregulated protein N-glycosylation related to Alzheimer's disease.

Pengyuan Yang, Lei Zhang, Jun Yao, 2019, Analytical chemistry.

Chemical labeling for fine mapping of IgG N-glycosylation by ETD-MS† †Electronic supplementary information (ESI) available: Materials and experimental procedures, eleven supplementary figures and six supplementary tables. See DOI: 10.1039/c9sc02491c

Haojie Lu, Lei Zhang, Ying Zhang, 2019, Chemical science.

MdCDPM: A Mass Defect based Chemical-Directed Proteomics Method for Targeted Analysis of Intact Sialylglycopeptides.

Haojie Lu, Lei Zhang, Jun Yao, 2019, Analytical chemistry.

Cancer Serum Atlas supported precise pan-targeted proteomics enable multi-cancer detection

Lei Zhang, X. Gao, Anqi Hu, 2022, medRxiv.

Pan‐targeted quantification of deep and comprehensive cancer serum proteome improves cancer detection

Lei Zhang, Anqi Hu, Huali Shen, 2023, VIEW.

Highly specific revelation of rat serum glycopeptidome by boronic acid-functionalized mesoporous silica.

Haojie Lu, Pengyuan Yang, Lei Zhang, 2012, Analytica chimica acta.

Selective Identification and Site-Specific Quantification of 4-Hydroxy-2-nonenal-Modified Proteins.

Haojie Lu, Caiyun Fang, Lei Zhang, 2019, Analytical chemistry.

Enhancing Comprehensive Analysis of Newly Synthesized Proteins Based on Cleavable Bioorthogonal Tagging.

Haojie Lu, Lei Zhang, Jun Yao, 2021, Analytical chemistry.

C24‐Ceramide Drives Gallbladder Cancer Progression Through Directly Targeting Phosphatidylinositol 5‐Phosphate 4‐Kinase Type‐2 Gamma to Facilitate Mammalian Target of Rapamycin Signaling Activation

Lei Zhang, Yonglong Zhang, Haolu Wang, 2020 .

Lei Zhang, Yonglong Zhang, Haolu Wang, 2020, Hepatology.

Enhanced N-glycosylation site exploitation of sialoglycopeptides by peptide IPG-IEF assisted TiO2 chromatography

Pengyuan Yang, Lei Zhang, Jun Yao, 2012, Glycoconjugate Journal.

Efficient and accurate glycopeptide identification pipeline for high-throughput site-specific N-glycosylation analysis.

F. He, Haojie Lu, Pengyuan Yang, 2014, Journal of proteome research.

An outer membrane protease OmpT based strategy for simplified analysis of histone post-translational modifications by mass spectrometry.

Pengyuan Yang, Lei Zhang, Jun Yao, 2019, Analytical chemistry.

Quantitative analysis of post-translational modifications of histone H3 variants during the cell cycle.

Pengyuan Yang, Lei Zhang, Hong Jin, 2019, Analytica chimica acta.

BCAA–BCKA axis regulates WAT browning through acetylation of PRDM16

Lei Zhang, Feng Xu, Q. Lei, 2022, Nature Metabolism.

Identification of Palmitoylated Transitional Endoplasmic Reticulum ATPase by Proteomic Technique and Pan Antipalmitoylation Antibody.

Haojie Lu, Caiyun Fang, Pengyuan Yang, 2016, Journal of proteome research.

Screening and diagnosis of colorectal cancer and advanced adenoma by Bionic Glycome method and machine learning.

Lei Zhang, Rongrong Zhang, J. Dai, 2021, American journal of cancer research.

Mass defect-based carbonyl activated tags (mdCATs) for multiplex data-independent acquisition proteome quantification.

Haojie Lu, Lei Zhang, Jun Yao, 2021, Chemical communications.

A novel triplex isobaric termini labeling quantitative approach for simultaneously supplying three quantitative sources.

Haojie Lu, Peng-Yuan Yang, Lei Zhang, 2018, Analytica chimica acta.

A novel quantitative proteomics workflow by isobaric terminal labeling.

Lei Zhang, Peng-Yuan Yang, Shu-Jun Yang, 2012, Journal of proteomics.

Selective enrichment of metal-binding proteins based on magnetic core/shell microspheres functionalized with metal cations.

Haojie Lu, Caiyun Fang, Lei Zhang, 2015, The Analyst.

Fast Discrimination of Sialylated N-Glycan Linkage Isomers with One-Step Derivatization by Microfluidic Capillary Electrophoresis-Mass Spectrometry.

Haojie Lu, Lei Zhang, Wenning Wang, 2022, Analytical chemistry.

Specific Analysis of α-2,3-Sialylated N-Glycan Linkage Isomers by Microchip Capillary Electrophoresis-Mass Spectrometry.

Haojie Lu, Lei Zhang, Jun Yao, 2021, Analytical chemistry.

Ultrasensitive Trace Sample Proteomics Unraveled the Protein Remodeling during Mesenchymal-Amoeboid Transition.

Pengyuan Yang, Lei Zhang, Xiaohui Liu, 2021, Analytical chemistry.

Screening of missing proteins in the human liver proteome by improved MRM-approach-based targeted proteomics.

Chen Chen, Lei Zhang, Pengyuan Yang, 2014, Journal of proteome research.

Analysis of Serum Paraoxonase 1 Using Mass Spectrometry and Lectin Immunoassay in Patients With Alpha-Fetoprotein Negative Hepatocellular Carcinoma

Haojie Lu, Lei Zhang, H. Shu, 2021, Frontiers in Oncology.

Approach for identification and quantification of C-terminal peptides: incorporation of isotopic arginine labeling based on oxazolone chemistry.

Haojie Lu, Pengyuan Yang, Lei Zhang, 2013, Analytical chemistry.

High-throughput site-specific N-glycoproteomics reveals glyco-signatures for liver disease diagnosis

Lei Zhang, Ying Zhang, Zhenyu Sun, 2022, National science review.

Poly-hydroxylated bile acids and their prognostic roles in Alagille syndrome

Lei Zhang, Jun Han, Renxue Wang, 2023, World Journal of Pediatrics.

MdFDIA: A Mass Defect Based Four-Plex Data-Independent Acquisition Strategy for Proteome Quantification.

Haojie Lu, Lei Zhang, Yi Di, 2017, Analytical chemistry.

Enhanced N-glycosylation site exploitation of sialoglycopeptides by peptide IPG-IEF assisted TiO2 chromatography

Pengyuan Yang, Lei Zhang, Jun Yao, 2012, Glycoconjugate Journal.

Facile synthesis of novel magnetic silica nanoparticles functionalized with layer-by-layer detonation nanodiamonds for secretome study.

Haojie Lu, Pengyuan Yang, Lei Zhang, 2015, The Analyst.

Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer

C. Lian, Yiming Li, Pengyuan Yang, 2018, Nature.

A straightforward and highly efficient strategy for hepatocellular carcinoma glycoprotein biomarker discovery using a nonglycopeptide-based mass spectrometry (NGP-MS) pipeline.

Pengyuan Yang, Lei Zhang, Jun Yao, 2019, Analytical chemistry.