B. Chang

发表

Physical Stability of Protein Pharmaceuticals

B. Yeung, B. Chang, Byeong S. Chang, 2010 .

Development of Thermostable Lyophilized Sabin Inactivated Poliovirus Vaccine

B. Chang, Jae U. Jung, Woo-Jin Shin, 2018, mBio.

Formation of an active dimer during storage of interleukin-1 receptor antagonist in aqueous solution.

T. Arakawa, L. Narhi, B. Chang, 1996, Biophysical journal.

[The effects of protein stabilizers on aggregation induced by multiple-stresses].

T. Arakawa, B. Chang, D. Dix, 2003, Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.

Physical factors affecting the storage stability of freeze-dried interleukin-1 receptor antagonist: glass transition and protein conformation.

B. Chang, J. Carpenter, A. Dong, 1996, Archives of biochemistry and biophysics.

Use of subambient thermal analysis to optimize protein lyophilization

B. Chang, C. Randall, C. S. Randall, 1992 .

Mechanism for benzyl alcohol-induced aggregation of recombinant human interleukin-1 receptor antagonist in aqueous solution.

B. Chang, M. Manning, B. Kerwin, 2004, Journal of Pharmacy and Science.

Development of a Stable Freeze-dried Formulation of Recombinant Human Interleukin-1 Receptor Antagonist

G. Reeder, B. Chang, J. Carpenter, 1996, Pharmaceutical Research.

Lyophilization of Protein Pharmaceuticals

B. Chang, J. Carpenter, 2020 .

Purification and thermostability of β-galactosidase (lactase) from an autolytic strain of Streptococcus salivarius subsp. thermophilus

B. Chang, R. R. Mahoney, 1989, Journal of Dairy Research.

Calcium-dependent catalytic activity of a novel phytase from Bacillus amyloliquefaciens DS11.

B. Oh, T. Oh, B. Chang, 2001, Biochemistry.

Interactions between PEG and type I soluble tumor necrosis factor receptor: Modulation by pH and by PEGylation at the N terminus

B. Chang, B. Kerwin, G. Strambini, 2002, Protein science : a publication of the Protein Society.

Physical stabilization of proteins in aqueous solution.

B. Chang, Tiansheng Li, B. Kendrick, 2002, Pharmaceutical biotechnology.

Hydrogen bonding between sugar and protein is responsible for inhibition of dehydration-induced protein unfolding.

B. Chang, S. Allison, J. Carpenter, 1999, Archives of biochemistry and biophysics.

Preferential exclusion of sucrose from recombinant interleukin-1 receptor antagonist: role in restricted conformational mobility and compaction of native state.

B. Chang, M. Manning, J. Carpenter, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Surface-induced denaturation of proteins during freezing and its inhibition by surfactants.

B. Chang, J. Carpenter, J F Carpenter, 1996, Journal of pharmaceutical sciences.

Thermal Inactivation Kinetics of Horseradish Peroxidase

D. B. Lund, B. Chang, K. H. Park, 1988 .

Stabilization of Lyophilized Porcine Pancreatic Elastase

B. Chang, C. Randall, Y. S. Lee, 1993, Pharmaceutical Research.

Effects of sucrose on conformational equilibria and fluctuations within the native‐state ensemble of proteins

B. Chang, M. Manning, J. Carpenter, 2003, Protein science : a publication of the Protein Society.

Enzyme thermostabilization by bovine serum albumin and other proteins: evidence for hydrophobic interactions.

B. Chang, R. R. Mahoney, B S Chang, 1995, Biotechnology and applied biochemistry.

Freeze-drying Process Development for Protein Pharmaceuticals

B. Chang, Byeong S. Chang, Sugunakar Y. Patro, 2004 .

Rational Design of Stable Lyophilized Protein Formulations: Some Practical Advice

Michael J. Pikal, John F. Carpenter, Theodore W. Randolph, 1997, Pharmaceutical Research.

Roles of conformational stability and colloidal stability in the aggregation of recombinant human granulocyte colony‐stimulating factor

Theodore W Randolph, Brent S Kendrick, Eva Y Chi, 2003, Protein science : a publication of the Protein Society.

Inhibition of stress-induced aggregation of protein therapeutics.

M C Manning, B. Chang, M. Manning, 1999, Methods in enzymology.

Protein formulation and fill-finish operations.

Erwin Freund, B. Chang, E. Freund, 2002, Biotechnology annual review.

Aggregation of granulocyte colony stimulating factor under physiological conditions: characterization and thermodynamic inhibition.

Theodore W Randolph, Mark C Manning, Eva Y Chi, 2002, Biochemistry.

Effects of solutes on solubilization and refolding of proteins from inclusion bodies with high hydrostatic pressure

B. Chang, J. Carpenter, T. Randolph, 2006, Protein science : a publication of the Protein Society.

Development of an Efficient Single-Step Freeze-Drying Cycle for Protein Formulations

B. Chang, N. Fischer, Byeong S. Chang, 1995, Pharmaceutical Research.

Factors affecting the thermostability of β-galactosidase (Streptococcus salivarius subsp. thermophilus) in milk: a quantitative study

B. Chang, R. R. Mahoney, 1989, Journal of Dairy Research.

Reversibility of Heat-Induced Denaturation of the Recombinant Human Megakaryocyte Growth and Development Factor

T. Arakawa, J. Philo, L. Narhi, 1999, Pharmaceutical Research.

Practical approaches to protein formulation development.

Susan Hershenson, B. Chang, S. Hershenson, 2002, Pharmaceutical biotechnology.

Thermal denaturation of β-galactosidase from Streptococcus thermophilus and its stabilization by bovine serum albumin : an electrophoretic study

B. Chang, R. Mahoney, 1994 .

Online size-exclusion high-performance liquid chromatography light scattering and differential refractometry methods to determine degree of polymer conjugation to proteins and protein-protein or protein-ligand association states.

J. Philo, B. Chang, B. Kerwin, 2001, Analytical biochemistry.

Substrate‐induced Thermal Stabilization of Lactase (Escherichia coli) in Milk

B. Chang, T. Wilder, R. Mahoney, 1988 .

Identification of Asp95as the Site of Succinimide Formation in Recombinant Human Glial Cell Line-Derived Neurotrophic Factor

Michael F. Rohde, John H. Robinson, V. Katta, 1998 .