M. Manning

发表

Stability of Protein Pharmaceuticals: An Update

Brian M. Murphy, Robert W. Payne, M. Manning, 2010, Pharmaceutical Research.

Characterization of amorphous solids with weak glass transitions using high ramp rate differential scanning calorimetry.

K. Menard, P. Setlow, M. Manning, 2008, Journal of pharmaceutical sciences.

Infrared and circular dichroism spectroscopic characterization of structural differences between beta-lactoglobulin A and B.

M. Manning, S. Allison, J. Carpenter, 1996, Biochemistry.

Stability of Protein Pharmaceuticals

R. Borchardt, M. Manning, K. Patel, 1989, Pharmaceutical Research.

In vivo pathways of degradation and strategies for protein stabilization

M. Manning, T. J. Ahern, 1992 .

Product development issues for PEGylated proteins

Robert W. Payne, M. Manning, B. Murphy, 2011, Pharmaceutical development and technology.

Congo Red Populates Partially Unfolded States of an Amyloidogenic Protein to Enhance Aggregation and Amyloid Fibril Formation*

M. Manning, J. Carpenter, T. Randolph, 2003, The Journal of Biological Chemistry.

Controlled release of ionic compounds from poly (l-lactide) microspheres produced by precipitation with a compressed antisolvent

M. Manning, T. Randolph, R. F. Falk, 1997 .

Effect of Tween 20 on freeze-thawing- and agitation-induced aggregation of recombinant human factor XIII.

M. Manning, S. Frokjaer, J. Flink, 1998, Journal of pharmaceutical sciences.

Characterization of the solution conformations of leuprolide acetate.

M. Manning, D. V. Vander Velde, J. Meyer, 2002, The journal of peptide research : official journal of the American Peptide Society.

Stability of lyophilized sucrose formulations of an IgG1: subvisible particle formation

Robert W. Payne, M. Manning, B. Murphy, 2013, Pharmaceutical development and technology.

Rational Design of Stable Protein Formulations

M. Manning, J. Carpenter, 2002, Pharmaceutical Biotechnology.

Aggregation of recombinant human interferon gamma: kinetics and structural transitions.

M. Manning, J. Carpenter, T. Randolph, 1998, Journal of pharmaceutical sciences.

Retrospective statistical analysis of lyophilized protein formulations of progenipoietin using PLS: determination of the critical parameters for long-term storage stability.

Carol F. Kirchhoff, Robert E. Johnson, M. Manning, 2004, Journal of pharmaceutical sciences.

Heterogeneous nucleation-controlled particulate formation of recombinant human platelet-activating factor acetylhydrolase in pharmaceutical formulation.

M. Manning, J. Carpenter, E. Chi, 2005, Journal of pharmaceutical sciences.

Protein Stability During Bioprocessing

Robert W. Payne, M. Manning, Gabriel J. Evans, 2010 .

Noninvasive determination of protein conformation in the solid state using near infrared (NIR) spectroscopy.

M. Manning, J. Carpenter, R. Nayar, 2005, Journal of pharmaceutical sciences.

Effects of conformation on the chemical stability of pharmaceutically relevant polypeptides.

M. Manning, Jeffrey D. Meyer, B. Ho, 2002, Pharmaceutical biotechnology.

Intermolecular beta-sheet results from trifluoroethanol-induced nonnative alpha-helical structure in beta-sheet predominant proteins: infrared and circular dichroism spectroscopic study.

M. Manning, J. Carpenter, A. Dong, 1998, Archives of biochemistry and biophysics.

Generation of soluble and active subtilisin and alpha-chymotrypsin in organic solvents via hydrophobic ion pairing.

P. Bryan, M. Manning, J. Matsuura, 2009, International journal of peptide and protein research.

Long chain arginine esters: a new class of cationic detergents for preparation of hydrophobic ion-paired complexes.

M. Manning, D. Kroll, D. J. Claffey, 2000, Biochemistry and cell biology = Biochimie et biologie cellulaire.

The use of fluorescence resonance energy transfer to monitor dynamic changes of lipid-DNA interactions during lipoplex formation.

T. Anchordoquy, M. Manning, Ye Zhang, 2003, Biochimica et biophysica acta.

A Chemometric Approach Towards Predicting The Relative Aggregation Propensity: Aβ(1-42).

C. Henry, M. Manning, Nathaniel Zbacnik, 2019, Journal of pharmaceutical sciences.

In vitro and in vivo evaluation of the effects of PLA microparticle crystallinity on cellular response.

M. Manning, C. Lengsfeld, T. Randolph, 2003, Journal of controlled release : official journal of the Controlled Release Society.

Infrared spectroscopic studies of protein formulations containing glycine.

R. Suryanarayanan, M. Manning, J. Carpenter, 2004, Journal of pharmaceutical sciences.

Comparison of the secondary structures of human class I and class II major histocompatibility complex antigens by Fourier transform infrared and circular dichroism spectroscopy.

J. Strominger, W. Caughey, R. Woody, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Evaluation of Cisplatin in Combination with a Biologic Response Modifier in a Murine Mammary Carcinoma Model

M. Manning, C. A. Kuntz, E. Morello, 2002, Cancer investigation.

Comparative fourier transform infrared and circular dichroism spectroscopic analysis of alpha1-proteinase inhibitor and ovalbumin in aqueous solution.

M. Manning, J. Carpenter, A. Dong, 2000, Archives of biochemistry and biophysics.

Humoral and cellular immune responses following vaccination with purified recombinant hemagglutinin from influenza A (H3N2) virus.

M. Manning, J. McElhaney, D. Powers, 1997, The Journal of infectious diseases.

Feasibility of Tissue Plasminogen Activator Formulated for Pulmonary Delivery

M. Manning, K. Stringer, J. Repine, 2005, Pharmaceutical Research.

Molecular orbital calculations on the oligopeptides netropsin, distamycin and related compounds

R. Woody, M. Manning, 1986, Biopolymers.

Effects of drying methods and additives on structure and function of actin: mechanisms of dehydration-induced damage and its inhibition.

K. Middleton, M. Manning, S. Allison, 1998, Archives of biochemistry and biophysics.

Enhanced solubility of proteins and peptides in nonpolar solvents through hydrophobic ion pairing

M. Manning, J. Matsuura, E. Shefter, 1993 .

Optimization of storage stability of lyophilized actin using combinations of disaccharides and dextran.

K. Middleton, M. Manning, S. Allison, 2000, Journal of pharmaceutical sciences.

Mechanism for benzyl alcohol-induced aggregation of recombinant human interleukin-1 receptor antagonist in aqueous solution.

B. Chang, M. Manning, B. Kerwin, 2004, Journal of Pharmacy and Science.

Thermal stability of low molecular weight urokinase during heat treatment. III. Effect of salts, sugars and Tween 80

M. Vrkljan, J. Henkin, M. Manning, 1996 .

In vitro release kinetics of gentamycin from a sodium hyaluronate gel delivery system suitable for the treatment of peripheral vestibular disease.

M. Manning, D. Malone, J. Matsuura, 1999, Drug development and industrial pharmacy.

Effects of potassium bromide disk formation on the infrared spectra of dried model proteins.

M. Manning, J. Carpenter, Jeffrey D. Meyer, 2004, Journal of pharmaceutical sciences.

The effects of Tween 20 and sucrose on the stability of anti-L-selectin during lyophilization and reconstitution.

G. Winter, M. Manning, J. Carpenter, 2001, Journal of pharmaceutical sciences.

Secondary structure of antifreeze proteins from overwintering larvae of the beetle Dendroides canadensis.

M. Manning, J. Carpenter, J. Duman, 1998, Archives of biochemistry and biophysics.

Spectroscopic study of secondary structure and thermal denaturation of recombinant human factor XIII in aqueous solution.

M. Manning, J. Carpenter, A. Dong, 1997, Archives of biochemistry and biophysics.

Hydrophobic ion pairing as a method for enhancing structure and activity of lyophilized subtilisin BPN' suspended in isooctane.

M. Manning, J. Carpenter, J. Matsuura, 1997, Archives of Biochemistry and Biophysics.

Quantitation of the area of overlap between second-derivative amide I infrared spectra to determine the structural similarity of a protein in different states.

M. Manning, S. Allison, J. Carpenter, 1996, Journal of pharmaceutical sciences.

Drug delivery matrix containing native protein precipitates suspended in a poloxamer gel.

M. Manning, J. Carpenter, A. Dong, 1997, Journal of pharmaceutical sciences.

Stability of Human Serum Albumin During Bioprocessing: Denaturation and Aggregation During Processing of Albumin Paste

M. Manning, J. Carpenter, Jeffrey D. Meyer, 2000, Pharmaceutical Research.

Effect of zinc binding and precipitation on structures of recombinant human growth hormone and nerve growth factor.

M. Manning, J. Carpenter, T. Randolph, 2000, Journal of pharmaceutical sciences.

Heat-Induced Gel Formation of .beta.-Lactoglobulin: A Study on the Secondary and Tertiary Structure As Followed by Circular Dichroism Spectroscopy

M. Manning, J. Matsuura, 1994 .

Microparticle-based lung delivery of INH decreases INH metabolism and targets alveolar macrophages.

U. Christians, M. Manning, T. Randolph, 2005, Journal of controlled release : official journal of the Controlled Release Society.

Stability of the Thrombolytic Protein Fibrolase: Effect of Temperature and pH on Activity and Conformation

J. W. Mitchell, M. Manning, D. V. Vander Velde, 1991, Pharmaceutical Research.

Tyrosine, phenylalanine, and disulfide contributions to the circular dichroism of proteins: circular dichroism spectra of wild-type and mutant bovine pancreatic trypsin inhibitor.

M C Manning, D. Goldenberg, N. Sreerama, 1999, Biochemistry.

Ability of Two Natural Products, Nootkatone and Carvacrol, to Suppress Ixodes scapularis and Amblyomma americanum (Acari: Ixodidae) in a Lyme Disease Endemic Area of New Jersey

M. Manning, J. Piesman, J. Karchesy, 2009, Journal of economic entomology.

Effect of secondary structure on the activity of enzymes suspended in organic solvents.

M. Manning, J. Carpenter, A. Dong, 1996, Archives of biochemistry and biophysics.

High throughput detection of deamidation using S‐(5′‐adenosyl)‐l‐homocysteine hydrolase and a fluorogenic reagent

C. Henry, M. Manning, B. Murphy, 2018, Journal of pharmaceutical and biomedical analysis.

Shape Characterization of Subvisible Particles Using Dynamic Imaging Analysis.

G. Winter, M. Manning, R. Mathaes, 2019, Journal of pharmaceutical sciences.

Use of circular dichroism spectroscopy in determining the conformation of a monoclonal antibody prior to its incorporation in an immunoliposome.

M. Manning, L. Zhao, J. Meyer, 1997, Journal of pharmaceutical and biomedical analysis.

Solution behavior of α‐chymotrypsin dissolved in nonpolar organic solvents via hydrophobic ion pairing

M. Manning, J. Matsuura, Jeffrey D. Meyer, 1995 .

Alveolar macrophage cell line is not activated by exposure to polymeric microspheres

D. Thompson, M. Manning, K. Stringer, 1998 .

Circular dichroism studies of distorted alpha-helices, twisted beta-sheets, and beta turns.

M. Illangasekare, R. Woody, M. Manning, 1988, Biophysical chemistry.

Preparation and in vitro characterization of gentamycin-impregnated biodegradable beads suitable for treatment of osteomyelitis.

M. Manning, D. Kroll, T. Randolph, 1998, Journal of pharmaceutical sciences.

Effect of Zinc Binding on the Structure and Stability of Fibrolase, a Fibrinolytic Protein from Snake Venom

J. W. Mitchell, M. Manning, D. V. Vander Velde, 1992, Pharmaceutical Research.

Fibrolase. A fibrinolytic protein from snake venom.

M. Manning, D. V. Vander Velde, D. Pretzer, 1993, Pharmaceutical biotechnology.

Effects of Tween 20 and Tween 80 on the stability of Albutropin during agitation.

M. Manning, Danny K. Chou, J. Carpenter, 2005, Journal of pharmaceutical sciences.

Structure and stability of insulin dissolved in 1-octanol

M. Manning, J. Matsuura, E. Shefter, 1993 .

Theoretical CD studies of polypeptide helices: Examination of important electronic and geometric factors

R. Woody, M. Manning, 1991, Biopolymers.

Circular dichroism studies of distorted α-helices, twisted β-sheets, and β-turns

M. Illangasekare, R. Woody, M. Manning, 1988 .

Binding of pyridoxal 5'-phosphate to the heme protein human cystathionine beta-synthase.

M. Manning, J. Kraus, V. Kéry, 1999, Biochemistry.

Preferential exclusion of sucrose from recombinant interleukin-1 receptor antagonist: role in restricted conformational mobility and compaction of native state.

B. Chang, M. Manning, J. Carpenter, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Lipid unsaturation determines the interaction of AFP type I with model membranes during thermotropic phase transitions.

D. Hincha, M. Manning, J. Crowe, 2002, Cryobiology.

Chemical Instability in Peptide and Protein Pharmaceuticals

Elizabeth M. Topp, Robert W. Payne, Mark Manning, 2010 .

Role of Buffers in Protein Formulations.

Charles S Henry, Robert W. Payne, Ryan E Holcomb, 2017, Journal of pharmaceutical sciences.

Impact of bulking agents on the stability of a lyophilized monoclonal antibody.

M. Manning, R. Nayar, Jeffrey D. Meyer, 2009, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Chapter 6 Analysis of protein structure by circular dichroism spectroscopy

M. Manning, J. Towell, 1994 .

The phage lambda terminase enzyme: 2. Refolding of the gpNu1 subunit from the detergent-denatured and guanidinium hydrochloride-denatured state yields different oligomerization states and altered protein stabilities.

M. Manning, C. Catalano, J. Meyer, 1998, International journal of biological macromolecules.

Intermolecular β-Sheet Results from Trifluoroethanol-Induced Nonnative α-Helical Structure in β-Sheet Predominant Proteins: Infrared and Circular Dichroism Spectroscopic Study

M. Manning, J. Carpenter, A. Dong, 1998 .

Effects of sucrose on conformational equilibria and fluctuations within the native‐state ensemble of proteins

B. Chang, M. Manning, J. Carpenter, 2003, Protein science : a publication of the Protein Society.

Improved potency of cisplatin by hydrophobic ion pairing

M. Manning, Leia M. Smith, W. Dernell, 2004, Cancer Chemotherapy and Pharmacology.

Two-, three-, and four-dimensional nuclear magnetic resonance spectroscopy of protein pharmaceuticals.

M. Manning, J. Matsuura, D. V. Vander Velde, 1995, Pharmaceutical biotechnology.

Secondary structure of recombinant human cystathionine beta-synthase in aqueous solution: effect of ligand binding and proteolytic truncation.

M. Manning, J. Carpenter, J. Kraus, 1997, Archives of biochemistry and biophysics.

in Vivo Evaluation of Gentamicin Impregnated Polylactic Acid Beads Implanted in Sheep

M. Manning, J. Shively, C. A. Kuntz, 2001 .

Comparison of the Secondary Structures of Human Class I and Class II MHC Antigens by Ftir and CD Spectroscopy

J. Strominger, W. Caughey, R. Woody, 1989 .

Cytotoxic T lymphocyte responses to a liposome-adjuvanted influenza A virus vaccine in the elderly.

M. Manning, P. Pietrobon, D. Powers, 1995, The Journal of infectious diseases.

Domain structure of gpNu1, a phage lambda DNA packaging protein.

M. Manning, C. Catalano, Q. Yang, 1999, Biochemistry.

Second virial coefficient studies of cosolvent-induced protein self-interaction.

C. Henry, M. Manning, K. Verma, 2005, Biophysical journal.

Vaccine Design

M. Manning, M. Newman, M. Mohler, 1995, Pharmaceutical Biotechnology.

alphaT244M mutation affects the redox, kinetic, and in vitro folding properties of Paracoccus denitrificans electron transfer flavoprotein.

M. Manning, J. Carpenter, F. Frerman, 1997, Biochemistry.

Denaturation and Aggregation of Interferon-τ in Aqueous Solution

Robert W. Payne, C. Henry, M. Manning, 2018, Pharmaceutical Research.

Physical stability of albinterferon-α(2b) in aqueous solution: effects of conformational stability and colloidal stability on aggregation.

Theodore W Randolph, John F Carpenter, Danny K Chou, 2012, Journal of pharmaceutical sciences.

Tween protects recombinant human growth hormone against agitation-induced damage via hydrophobic interactions.

J L Cleland, M C Manning, R. Kelley, 1998, Journal of pharmaceutical sciences.

The phage lambda terminase enzyme: 1. Reconstitution of the holoenzyme from the individual subunits enhances the thermal stability of the small subunit.

M. Manning, C. Catalano, J. Meyer, 1998, International journal of biological macromolecules.

Cloning, expression, and characterization of a DNA binding domain of gpNu1, a phage lambda DNA packaging protein.

M. Overduin, M. Manning, C. Catalano, 1999, Biochemistry.

Underlying assumptions in the estimation of secondary structure content in proteins by circular dichroism spectroscopy--a critical review.

M. Manning, Mark C. Manning, 1989, Journal of pharmaceutical and biomedical analysis.

Conformation of human calcitonin gene-related peptide (8-37) in aqueous solution as determined by circular dichroism spectroscopy.

M. Manning, J. Matsuura, 1993, Journal of pharmaceutical and biomedical analysis.

Stability of lyophilized teriparatide, PTH(1-34), after reconstitution.

Robert W. Payne, C. Henry, M. Manning, 2016, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Solution behavior of leuprolide acetate, an LHRH agonist, as determined by circular dichroism spectroscopy

M. Manning, Mou-Ying Gu Lu, A. Adjei, 1994 .

Theoretical study of the contribution of aromatic side chains to the circular dichroism of basic bovine pancreatic trypsin inhibitor.

R. Woody, M. Manning, 1989, Biochemistry.

Conformation of the alpha form of human calcitonin gene-related peptide (CGRP) in aqueous solution as determined by circular dichroism spectroscopy.

M. Manning, 1989, Biochemical and biophysical research communications.

Inhibition of stress-induced aggregation of protein therapeutics.

M C Manning, B. Chang, M. Manning, 1999, Methods in enzymology.

Counteracting Effects of Renal Solutes on Amyloid Fibril Formation by Immunoglobulin Light Chains*

M. Manning, J. Carpenter, E. Chi, 2001, The Journal of Biological Chemistry.

The helix–coil transition in heterogeneous peptides with specific side‐chain interactions: Theory and comparison with CD spectral data

N. Kallenbach, R. Woody, M. Manning, 1991, Biopolymers.

Sequence analysis of fibrolase, a fibrinolytic metalloproteinase from Agkistrodon contortrix contortrix.

M. Manning, 1995, Toxicon : official journal of the International Society on Toxinology.

Comparability of higher order structure in proteins: chemometric analysis of second-derivative amide I Fourier transform infrared spectra.

Gregory W. Stockdale, M. Manning, B. Murphy, 2015, Journal of pharmaceutical sciences.

Degradation kinetics of high molecular weight poly(L-lactide) microspheres and release mechanism of lipid:DNA complexes.

Mayank M. Patel, T. Anchordoquy, M. Manning, 2004, Journal of pharmaceutical sciences.

Mixing properties of lyophilized protein systems: a spectroscopic and calorimetric study.

K. Menard, M. Manning, D. Katayama, 2009, Journal of pharmaceutical sciences.

Thermal Stability of Low Molecular Weight Urokinase During Heat Treatment. II. Effect of Polymeric Additives

John F. Carpenter, M. Vrkljan, J. Henkin, 1994, Pharmaceutical Research.

The stability factor: importance in formulation development.

Mark C Manning, M. Manning, Rajesh Krishnamurthy, 2002, Current pharmaceutical biotechnology.

Aggregation of granulocyte colony stimulating factor under physiological conditions: characterization and thermodynamic inhibition.

Theodore W Randolph, Mark C Manning, Eva Y Chi, 2002, Biochemistry.

High throughput formulation: strategies for rapid development of stable protein products.

Mark C Manning, M. Manning, R. Nayar, 2002, Pharmaceutical biotechnology.

Prediction of Aggregation Propensity from Primary Sequence Information

Robert W. Payne, M. Manning, G. J. Evans, 2010 .

Controlling deamidation rates in a model peptide: effects of temperature, peptide concentration, and additives.

M C Manning, M. Manning, J. Shively, 2001, Journal of pharmaceutical sciences.

Protease autolysis in heavy-duty liquid detergent formulations: effects of thermodynamic stabilizers and protease inhibitors

M. Manning, J. Carpenter, T. Randolph, 2004 .

Use of infrared spectroscopy to monitor protein structure and stability

M. Manning, Mark Cornell Manning, 2005, Expert review of proteomics.

Thermodynamic Modulation of Light Chain Amyloid Fibril Formation*

M. Manning, J. Carpenter, T. Randolph, 2000, The Journal of Biological Chemistry.

Flow imaging: moving toward best practices for subvisible particle quantitation in protein products.

M. Manning, Glenn A Wilson, 2013, Journal of pharmaceutical sciences.

Thermal stability of low molecular weight urokinase during heat treatment. I. Effects of protein concentration, pH and ionic strength.

W R Porter, M C Manning, M. Manning, 1993, Thrombosis research.

Protein instability following transport or storage on dry ice

Mark C Manning, M. Manning, B. Murphy, 2013, Nature Methods.

Hydrophobic Ion Pairing: Altering the Solubility Properties of Biomolecules

M. Manning, Jeffrey D. Meyer, 1998, Pharmaceutical Research.

Hydrophobic ion pairing of isoniazid using a prodrug approach.

M. Manning, C. Lengsfeld, T. Randolph, 2002, Journal of pharmaceutical sciences.

Selective Precipitation of Interleukin-4 Using Hydrophobic Ion Pairing: A Method for Improved Analysis of Proteins Formulated with Large Excesses of Human Serum Albumin

M. Manning, J. Matsuura, E. Shefter, 1994, Pharmaceutical Research.

Rational Design of Liquid Formulations of Proteins.

Mark C Manning, Jun Liu, Tiansheng Li, 2018, Advances in protein chemistry and structural biology.

Colloidal behavior of proteins: effects of the second virial coefficient on solubility, crystallization and aggregation of proteins in aqueous solution.

Charles S Henry, Robert W. Payne, C. Henry, 2005, Current pharmaceutical biotechnology.

Delta-sleep-inducing peptide: solution conformational studies of a membrane-permeable peptide.

M C Manning, R T Borchardt, R. Borchardt, 1994, Biochemistry.

Effects of solution conditions on methionine oxidation in albinterferon alfa-2b and the role of oxidation in its conformation and aggregation.

M. Manning, Danny K. Chou, J. Carpenter, 2013, Journal of pharmaceutical sciences.

Effect of buffer species on the thermally induced aggregation of interferon-tau.

C. Henry, M. Manning, Danny K. Chou, 2006, Journal of Pharmacy and Science.

Theoretical determination of the CD of proteins containing closely packed antiparallel β‐sheets

R. Woody, M. Manning, 1987, Biopolymers.

Aggregation of human serum albumin during a thermal viral inactivation step.

M. Manning, J. Carpenter, Jeffrey D. Meyer, 2009, International journal of biological macromolecules.

Chemical and physical pathways of protein degradation

M. Manning, T. J. Ahern, 1992 .

Use of the amide II infrared band of proteins for secondary structure determination and comparability of higher order structure.

M. Manning, B. Murphy, Wasfi A Al-Azzam, 2014, Current pharmaceutical biotechnology.

Aggregation of recombinant human botulinum protein antigen serotype C in varying solution conditions: implications of conformational stability for aggregation kinetics.

Theodore W Randolph, John F Carpenter, Shujun Bai, 2011, Journal of pharmaceutical sciences.

Comparability of protein therapeutics: quantitative comparison of second-derivative amide I infrared spectra.

M. Manning, B. Murphy, Wasfi A Al-Azzam, 2012, Journal of pharmaceutical sciences.

Long‐Term Storage of Proteins

Theodore W Randolph, John F Carpenter, Mark C Manning, 2002, Current protocols in protein science.

Structure, stability, and mobility of a lyophilized IgG1 monoclonal antibody as determined using second-derivative infrared spectroscopy.

Robert W. Payne, M. Manning, B. Murphy, 2012, Journal of pharmaceutical sciences.

Quantification of glycine crystallinity by near-infrared (NIR) spectroscopy.

R. Suryanarayanan, M. Manning, J. Carpenter, 2004, Journal of pharmaceutical sciences.

Encapsulating DNA within biodegradable polymeric microparticles.

M. Manning, C. Lengsfeld, T. Randolph, 2002, Current Pharmaceutical Biotechnology.

APPLICATION OF FORMULATION PRINCIPLES TO STABILITY ISSUES ENCOUNTERED DURING PROCESSING, MANUFACTURING, AND STORAGE OF DRUG SUBSTANCE AND DRUG PRODUCT PROTEIN THERAPEUTICS.

M. Manning, D. Katayama, Samadhi N Vitharana, 2023, Journal of pharmaceutical sciences.

Approaches for increasing the solution stability of proteins.

M C Manning, M. Vrkljan, M. Manning, 1995, Biotechnology and bioengineering.

Second virial coefficient determination of a therapeutic peptide by self‐interaction chromatography

Robert W. Payne, C. Henry, M. Manning, 2006, Biopolymers.

Multivariate Analysis of the Sequence Dependence of Asparagine Deamidation Rates in Peptides

Vasumathi Dharmavaram, M. Manning, Mark Cornell Manning, 2009, Pharmaceutical Research.

Effects of solution conditions on methionine oxidation in albinterferon alfa-2b and the role of oxidation in its conformation and aggregation.

M. Manning, Danny K. Chou, J. Carpenter, 2013, Journal of pharmaceutical sciences.