A. Balland

发表

Succinimide formation at Asn 55 in the complementarity determining region of a recombinant monoclonal antibody IgG1 heavy chain.

B. Yan, A. Lim, T. Arroll, 2009, Journal of pharmaceutical sciences.

Rapid identification of an antibody DNA construct rearrangement sequence variant by mass spectrometry

A. Balland, R. Scott, Lowell J. Brady, 2014, mAbs.

Electrophoretic evidence for the presence of structural isoforms specific for the IgG2 isotype

Randal R Ketchem, A. Balland, C. Jochheim, 2008, Electrophoresis.

Optimization of CE-SDS Method for Antibody Separation Based on Multi-Users Experimental Practices

Zac Yates, A. Balland, D. Phan, 2006 .

Evaluation of pI Marker Sources for cIEF Characterization of a Therapeutic Antibody

A. Balland, A. Guo, Mei Han, 2007 .

Characterization of Minor N-linked Glycans on Antibodies Using Endo H Release and MALDI–Mass Spectrometry

A. Balland, D. Pace, T. Martinez, 2009 .

O-fucosylation of an antibody light chain: characterization of a modification occurring on an IgG1 molecule.

B. Yan, John F. Valliere-Douglass, Alison Wallace, 2008, Glycobiology.

Resolving disulfide structural isoforms of IgG2 monoclonal antibodies by ion mobility mass spectrometry.

P. Schnier, John F. Valliere-Douglass, A. Balland, 2010, Analytical chemistry.

Isolation of a human anti-haemophilic factor IX cDNA clone using a unique 52-base synthetic oligonucleotide probe deduced from the amino acid sequence of bovine factor IX.

M. Jaye, H. de la Salle, A. Balland, 1983, Nucleic acids research.

Characterisation of two differently processed forms of human recombinant factor IX synthesised in CHO cells transformed with a polycistronic vector.

H. de la Salle, A. Balland, T. Faure, 1988, European journal of biochemistry.

Characterization of antibody charge heterogeneity resolved by preparative immobilized pH gradients.

A. Balland, Lowell J. Brady, A. Guo, 2010, Analytical chemistry.

Separation and characterization of an IgG2 antibody containing a cyclic imide in CDR1 of light chain by hydrophobic interaction chromatography and mass spectrometry.

John F. Valliere-Douglass, Alison Wallace, A. Balland, 2008, Analytical chemistry.

Characterization of recombinant human factor IX expressed in transgenic mice and in derived trans‐immortalized hepatic cell lines.

A. Balland, T. Faure, A. Pavirani, 1990, The EMBO journal.

Isolation from human cerebrospinal fluid of a new insulin‐like growth factor‐binding protein with a selective affinity for IGF‐II

A. Balland, P. Lepage, M. Binoux, 1989, FEBS letters.

Control of Antibody Impurities Induced by Riboflavin in Culture Media During Production.

John F. Valliere-Douglass, Alison Wallace, A. Balland, 2019, Journal of pharmaceutical sciences.

Transgenic Animals as a Source of Genetically-Engineered Trans-Immortalised Cell Lines

A. Balland, T. Faure, A. Pavirani, 1991 .

Analysis of Glycosylated Type II Interleukin-1 Receptor (IL-1R) by Imaged Capillary Isoelectric Focusing (i-cIEF)

A. Balland, C. Jochheim, A. Guo, 2007 .

Separation of Enbrel® (rhuTNFR: Fc) Isoforms by Capillary Isoelectric Focusing

A. Balland, A. Goetze, W. Gombotz, 2001 .

Silica gel: an improved support for the solid-phase phosphotriester synthesis of oligonucleotides.

M. Wintzerith, A. Balland, J. Lecocq, 1982, Nucleic acids research.

Structural and Functional Characterization of Disulfide Isoforms of the Human IgG2 Subclass*

Thomas M. Dillon, Alain Balland, Gregory C. Flynn, 2008, Journal of Biological Chemistry.

Photochemical degradation of citrate buffers leads to covalent acetonation of recombinant protein therapeutics

P. Schnier, John F. Valliere-Douglass, A. Balland, 2010, Protein science : a publication of the Protein Society.

Separation of populations of antibody variants by fine tuning of hydrophobic-interaction chromatography operating conditions.

Alain Balland, John Valliere-Douglass, John F. Valliere-Douglass, 2008, Journal of chromatography. A.

Characterization of nonenzymatic glycation on a monoclonal antibody.

Alain Balland, Lowell J Brady, A. Balland, 2007, Analytical chemistry.

Characterization of a novel modification on IgG2 light chain. Evidence for the presence of O-linked mannosylation.

M. Gerhart, A. Balland, Lowell J. Brady, 2007, Journal of chromatography. A.

Characterization of the microheterogeneities of PIXY321, a genetically engineered granulocyte-macrophage colony-stimulating factor/interleukin-3 fusion protein expressed in yeast.

M. Gerhart, A. Balland, D. Krasts, 1998, European journal of biochemistry.

Human IgG2 Antibodies Display Disulfide-mediated Structural Isoforms*

Ming Li, T. Dillon, P. Bondarenko, 2008, Journal of Biological Chemistry.

Development of a quantitative mass spectrometry multi-attribute method for characterization, quality control testing and disposition of biologics

Richard S Rogers, Nancy S Nightlinger, Brittney Livingston, 2015, mAbs.

Human IgG1 Hinge Fragmentation as the Result of H2O2-mediated Radical Cleavage

B. Yan, G. Kleemann, A. Balland, 2009, The Journal of Biological Chemistry.

Disulfide connectivity of human immunoglobulin G2 structural isoforms.

Alain Balland, Randal R Ketchem, A. Balland, 2008, Biochemistry.

Glutamine-linked and Non-consensus Asparagine-linked Oligosaccharides Present in Human Recombinant Antibodies Define Novel Protein Glycosylation Motifs

Alain Balland, Michael J Treuheit, Randal R Ketchem, 2010, The Journal of Biological Chemistry.

Asparagine-linked Oligosaccharides Present on a Non-consensus Amino Acid Sequence in the CH1 Domain of Human Antibodies

Alain Balland, B. Yan, John F. Valliere-Douglass, 2009, The Journal of Biological Chemistry.

Antibodies 1 Domain of HumanHSequence in the C Present on a Non-consensus Amino Acid Asparagine-linked Oligosaccharides Modification , and Degradation : Protein Synthesis , Post-Translational

B. Yan, A. Balland, M. Treuheit, 2009 .

Characterization of the isoforms of PIXY321, a granulocyte-macrophage-colony stimulating factor-interleukin-3 fusion protein, separated by preparative isoelectric focusing on immobilized pH gradients.

A. Balland, W. Gombotz, M. Daniels, 1999, Journal of chromatography. A.

Hydrophobic interaction chromatography of soluble interleukin I receptor type II to reveal chemical degradations resulting in loss of potency.

A. Balland, A. Goetze, Yuling Zhang, 2008, Analytical chemistry.

Mass Spectrometry for Biopharmaceutical Development

A. Balland, C. Jochheim, 2005 .

Analysis of post-translational modifications in recombinant monoclonal antibody IgG1 by reversed-phase liquid chromatography/mass spectrometry.

B. Yan, S. Steen, John F. Valliere-Douglass, 2007, Journal of chromatography. A.

In Vitro Carboxylation of a Blood Coagulation Factor IX Precursor Produced by Recombinant-DNA Technology

H. de la Salle, A. Balland, T. Faure, 1989, Thrombosis and Haemostasis.

High-level production of biologically active human alpha 1-antitrypsin in Escherichia coli.

R. Lathe, M. Jaye, A. Balland, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Interchain disulfide bonding in human IgG2 antibodies probed by site-directed mutagenesis.

T. Dillon, J. Wypych, A. Balland, 2009, Biochemistry.

Fluorescent derivatization method of proteins for characterization by capillary electrophoresis-sodium dodecyl sulfate with laser-induced fluorescence detection.

D. Michels, A. Balland, Lowell J. Brady, 2007, Analytical chemistry.

Use of synthetic oligonucleotides in gene isolation and manipulation.

H. de la Salle, A. Balland, E. Degryse, 1985, Biochimie.

Structural and Functional Characterization of Disulfide Isoforms of the Human IgG 2 Subclass *

Douglas S Rehder, T. Dillon, P. Bondarenko, 2008 .

Characterization of cysteine related variants in an IgG2 antibody by LC-MS with an automated data analysis approach.

A. Balland, Yuling Zhang, Robert Bailey, 2015, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Fusion of restriction termini using synthetic adaptor oligonucleotides.

R. Lathe, A. Balland, J. Lecocq, 1982, Gene.

Molecular mass analysis of antibodies by on-line SEC-MS

John F. Valliere-Douglass, A. Balland, Lowell J. Brady, 2008, Journal of the American Society for Mass Spectrometry.

Human IgG2 Antibodies Display Disulfide-mediated Structural Isoforms*

Ming Li, T. Dillon, P. Bondarenko, 2008, Journal of Biological Chemistry.

An optimized approach to the rapid assessment and detection of sequence variants in recombinant protein products

Alain Balland, Lowell J Brady, Rebecca A Scott, 2015, Analytical and Bioanalytical Chemistry.