M. Okuyama

发表

α-Glucosidases and α-1,4-glucan lyases: structures, functions, and physiological actions

M. Okuyama, W. Saburi, H. Mori, 2016, Cellular and Molecular Life Sciences.

A Novel Metabolic Pathway for Glucose Production Mediated by α-Glucosidase-catalyzed Conversion of 1,5-Anhydrofructose*

M. Okuyama, W. Saburi, H. Mori, 2012, The Journal of Biological Chemistry.

Streptococcus mutans Dextran Glucosidaseの基質認識機構

Atsuo, Mura, M. Okuyama, 2010 .

Streptococcus mutans Dextran

Atsuo, Mura, M. Okuyama, 2010 .

Structure-function relationship of substrate length specificity of dextran glucosidase from Streptococcus mutans

M. Okuyama, W. Saburi, H. Mori, 2008, Biologia.

Substrate recognition mechanism of alpha-1,6-glucosidic linkage hydrolyzing enzyme, dextran glucosidase from Streptococcus mutans.

Y. Matsuura, M. Okuyama, W. Saburi, 2008, Journal of molecular biology.

Molecular Mechanism of α-glucosidase

M. Okuyama, W. Saburi, H. Mori, 2008 .

Catalytic Amino Acid Residue Providing Proton Donor in a-Glucosidase Family II

M. Okuyama, H. Mori, A. Kimura, 2002 .

Characterization of a new oxygen-insensitive azoreductase from Brevibacillus laterosporus TISTR1911: toward dye decolorization using a packed-bed metal affinity reactor.

M. Okuyama, A. Kimura, S. Sirisansaneeyakul, 2013, Bioresource technology.

A novel glycoside hydrolase family 97 enzyme: Bifunctional β-l-arabinopyranosidase/α-galactosidase from Bacteroides thetaiotaomicron.

M. Yao, Yuya Kumagai, M. Okuyama, 2017, Biochimie.

Amino Acids in Conserved Region II Are Crucial to Substrate Specificity, Reaction Velocity, and Regioselectivity in the Transglucosylation of Honeybee GH-13 α-Glucosidases

M. Okuyama, H. Mori, A. Kimura, 2012, Bioscience, biotechnology, and biochemistry.

Glucoamylase Originating from Schwanniomyces occidentalis Is a Typical α-Glucosidase

M. Okuyama, H. Mori, A. Kimura, 2005 .

Glucoamylase originating from Schwanniomyces occidentalis is a typical alpha-glucosidase.

M. Okuyama, H. Mori, A. Kimura, 2005, Bioscience, biotechnology, and biochemistry.

Glycoside hydrolase family 31 Escherichia coli α-xylosidase

M. Okuyama, H. Mori, A. Kimura, 2008 .

Heat treatment of curdlan enhances the enzymatic production of biologically active β-(1,3)-glucan oligosaccharides.

Yuya Kumagai, M. Okuyama, A. Kimura, 2016, Carbohydrate polymers.

A novel mechanism for the promotion of quercetin glycoside absorption by megalo α-1,6-glucosaccharide in the rat small intestine.

S. Ishizuka, H. Hara, Yuya Kumagai, 2013, Food chemistry.

Characterization of an Unknown Region Linked to the Glycoside Hydrolase Family 17 β-1,3-Glucanase of Vibrio vulnificus Reveals a Novel Glucan-Binding Domain

Yuya Kumagai, M. Okuyama, A. Kimura, 2022, Marine drugs.

A practical approach to producing isomaltomegalosaccharide using dextran dextrinase from Gluconobacter oxydans ATCC 11894

Yuya Kumagai, M. Okuyama, W. Saburi, 2022, Applied Microbiology and Biotechnology.

Physicochemical functionality of chimeric isomaltomegalosaccharides with α-(1 → 4)-glucosidic segments of various lengths.

Yuya Kumagai, M. Okuyama, A. Kimura, 2022, Carbohydrate polymers.

In vitro antiproliferative/cytotoxic activity on cancer cell lines of a cardanol and a cardol enriched from Thai Apis mellifera propolis

M. Okuyama, H. Mori, A. Kimura, 2012, BMC Complementary and Alternative Medicine.

Novel α-1,3/α-1,4-Glucosidase from Aspergillus niger Exhibits Unique Transglucosylation to Generate High Levels of Nigerose and Kojibiose.

M. Okuyama, A. Kimura, A. Kikuchi, 2019, Journal of agricultural and food chemistry.

Substrate recognition of the catalytic α-subunit of glucosidase II from Schizosaccharomyces pombe

Yuya Kumagai, M. Okuyama, A. Kimura, 2017, Bioscience, biotechnology, and biochemistry.

Two Novel Glycoside Hydrolases Responsible for the Catabolism of Cyclobis-(1→6)-α-nigerosyl*

M. Okuyama, A. Kimura, T. Tagami, 2016, The Journal of Biological Chemistry.

Characterization of a Glycoside Hydrolase Family 31 α-Glucosidase Involved in Starch Utilization in Podospora anserina

M. Okuyama, H. Mori, A. Kimura, 2013, Bioscience, biotechnology, and biochemistry.

Purification and characterization of Acremonium implicatum α-glucosidase having regioselectivity for α-1,3-glucosidic linkage

M. Okuyama, H. Mori, A. Kimura, 2004 .

Crystallization and preliminary X-ray analysis of alpha-xylosidase from Escherichia coli.

I. Tanaka, M. Yao, M. Okuyama, 2005, Acta crystallographica. Section F, Structural biology and crystallization communications.

Extracellular and cell-associated forms of Gluconobacter oxydans dextran dextrinase change their localization depending on the cell growth.

M. Okuyama, W. Saburi, H. Mori, 2015, Biochemical and biophysical research communications.

Carboxyl group of residue Asp647 as possible proton donor in catalytic reaction of alpha-glucosidase from Schizosaccharomyces pombe.

M. Okuyama, H. Mori, A. Kimura, 2001, European journal of biochemistry.

Multiple forms of α-glucosidase in rice seeds (Oryza sativa L., var Nipponbare)

M. Okuyama, H. Mori, A. Kimura, 2007 .

Different molecular complexity of linear-isomaltomegalosaccharides and β-cyclodextrin on enhancing solubility of azo dye ethyl red: towards dye biodegradation.

Yuya Kumagai, M. Okuyama, H. Mori, 2014, Bioresource technology.

The Delay in the Development of Experimental Colitis from Isomaltosyloligosaccharides in Rats Is Dependent on the Degree of Polymerization

S. Ishizuka, Jae-Sung Lee, H. Hara, 2012, PloS one.

Structural Advantage of Sugar Beet α-Glucosidase to Stabilize the Michaelis Complex with Long-chain Substrate

M. Yao, M. Okuyama, H. Mori, 2014, The Journal of Biological Chemistry.

Characterization of some enzymatic properties of recombinant α-glucosidase III from the Thai honeybee, Apis cerana indica Fabricus

M. Okuyama, H. Mori, A. Kimura, 2012 .

A Solanum torvum GH3 β-glucosidase expressed in Pichia pastoris catalyzes the hydrolysis of furostanol glycoside.

M. Okuyama, A. Kimura, Hiroyuki Nakai, 2016, Phytochemistry.

α-Glucosidases and α-1,4-glucan lyases: structures, functions, and physiological actions

M. Okuyama, W. Saburi, H. Mori, 2016, Cellular and Molecular Life Sciences.

Rice α-glucosidase isozymes and isoforms showing different starch granules-binding and -degrading ability

M. Okuyama, H. Mori, A. Kimura, 2008 .

Identification of Essential Ionizable Groups and Evaluation of Subsite Affinities in the Active Site of β-D-Glucosidase F1 from a Streptomyces sp.

M. Okuyama, H. Mori, A. Kimura, 2002, Bioscience, biotechnology, and biochemistry.

Purification and characterization of a chloride ion-dependent alpha-glucosidase from the midgut gland of Japanese scallop (Patinopecten yessoensis)

M. Okuyama, H. Mori, A. Kimura, 2019 .

Purification and characterization of a chloride ion-dependent α-glucosidase from the midgut gland of Japanese scallop (Patinopecten yessoensis)

M. Okuyama, W. Saburi, H. Mori, 2016, Bioscience, biotechnology, and biochemistry.

Functional characterization of UDP‐rhamnose‐dependent rhamnosyltransferase involved in anthocyanin modification, a key enzyme determining blue coloration in Lobelia erinus

M. Okuyama, H. Shimura, Takashi Suzuki, 2017, The Plant journal : for cell and molecular biology.

α-Glucosidase Mutant Catalyzes “α-Glycosynthase”-type Reaction

M. Okuyama, H. Mori, A. Kimura, 2002 .

Kinetic Studies on Substrate Specificity and Active Site of β-D-Glucosidase F1 from Streptomyces sp.

M. Okuyama, H. Mori, A. Kimura, 2002 .

Truncation of N- and C-terminal regions of Streptococcus mutans dextranase enhances catalytic activity

M. Okuyama, H. Mori, A. Kimura, 2011, Applied Microbiology and Biotechnology.

The first alpha-1,3-glucosidase from bacterial origin belonging to glycoside hydrolase family 31.

M. Okuyama, H. Mori, A. Kimura, 2009, Biochimie.

Biochemical properties and substrate recognition mechanism of GH31 α-glucosidase from Bacillus sp. AHU 2001 with broad substrate specificity.

Yuya Kumagai, M. Okuyama, W. Saburi, 2015, Biochimie.

Nonreducing terminal chimeric isomaltomegalosaccharide and its integration with azoreductase for the remediation of soil-contaminated lipophilic azo dyes.

M. Okuyama, A. Kimura, N. Sakairi, 2023, Carbohydrate polymers.

Calcium Ion-Dependent Increase in Thermostability of Dextran Glucosidase from Streptococcus mutans

M. Okuyama, W. Saburi, H. Mori, 2011, Bioscience, biotechnology, and biochemistry.

Molecular Cloning of cDNAs and Genes for Three α-Glucosidases from European Honeybees, Apis mellifera L., and Heterologous Production of Recombinant Enzymes in Pichia pastoris

M. Okuyama, H. Mori, A. Kimura, 2007, Bioscience, biotechnology, and biochemistry.

Chemical constituents and free radical scavenging activity of corn pollen collected from Apis mellifera hives compared to floral corn pollen at Nan, Thailand

M. Okuyama, H. Mori, A. Kimura, 2012, BMC Complementary and Alternative Medicine.

Structural elements responsible for the glucosidic linkage‐selectivity of a glycoside hydrolase family 13 exo‐glucosidase

M. Okuyama, W. Saburi, H. Mori, 2015, FEBS Letters.

Catalytic role of the calcium ion in GH97 inverting glycoside hydrolase

M. Yao, M. Okuyama, H. Mori, 2014, FEBS letters.

Function and Structure Studies of GH Family 31 and 97 α-Glycosidases

M. Okuyama, 2011, Bioscience, biotechnology, and biochemistry.

Catalytic mechanism of retaining alpha-galactosidase belonging to glycoside hydrolase family 97.

I. Tanaka, M. Yao, M. Okuyama, 2009, Journal of molecular biology.

Structural and Functional Analysis of a Glycoside Hydrolase Family 97 Enzyme from Bacteroides thetaiotaomicron*

I. Tanaka, M. Yao, N. Watanabe, 2008, Journal of Biological Chemistry.

Purification and Identification of the Essential Ionizable Groups of Honeybee, Apis mellifera L., Trehalase

M. Okuyama, H. Mori, A. Kimura, 2001, Bioscience, biotechnology and biochemistry.

Molecular Basis for the Recognition of Long-chain Substrates by Plant α-Glucosidases

M. Yao, M. Okuyama, H. Mori, 2013, The Journal of Biological Chemistry.

Structural elements in dextran glucosidase responsible for high specificity to long chain substrate.

M. Okuyama, W. Saburi, H. Mori, 2006, Biochimica et biophysica acta.

Catalytic Reaction Mechanism Based on α-Secondary Deuterium Isotope Effects in Hydrolysis of Trehalose by European Honeybee Trehalase

M. Okuyama, H. Mori, A. Kimura, 2009, Bioscience, biotechnology, and biochemistry.

Molecular Cloning of cDNA for Trehalase from the European Honeybee, Apis mellifera L., and Its Heterologous Expression in Pichia pastoris

M. Okuyama, H. Mori, A. Kimura, 2007, Bioscience, biotechnology, and biochemistry.

Replacement of the Catalytic Nucleophile Aspartyl Residue of Dextran Glucosidase by Cysteine Sulfinate Enhances Transglycosylation Activity

M. Okuyama, W. Saburi, H. Mori, 2013, The Journal of Biological Chemistry.

Discovery of α-l-Glucosidase Raises the Possibility of α-l-Glucosides in Nature

M. Okuyama, A. Kimura, W. Lang, 2022, ACS omega.

Purification and characterization of the hyper-glycosylated extracellular α-glucosidase from Schizosaccharomyces pombe

Masayuki Okuyama, Hirokazu Matsui, M. Okuyama, 2005 .

Aromatic Residue on β→α Loop 1 in the Catalytic Domain Is Important to the Transglycosylation Specificity of Glycoside Hydrolase Family 31 α-Glucosidase

M. Okuyama, H. Mori, A. Kimura, 2013, Bioscience, biotechnology, and biochemistry.

Key aromatic residues at subsites +2 and +3 of glycoside hydrolase family 31 α-glucosidase contribute to recognition of long-chain substrates.

B. Svensson, M. Okuyama, H. Mori, 2013, Biochimica et biophysica acta.

Enzymatic synthesis of alkyl α-2-deoxyglucosides by alkyl alcohol resistant α-glucosidase from Aspergillus niger

M. Okuyama, W. Saburi, H. Mori, 2005 .

Overexpression and characterization of two unknown proteins, YicI and YihQ, originated from Escherichia coli.

Masayuki Okuyama, M. Okuyama, H. Mori, 2004, Protein expression and purification.

Aglycone specificity of Escherichia coliα‐xylosidase investigated by transxylosylation

M. Okuyama, H. Mori, A. Kimura, 2007, The FEBS journal.

Structural Elucidation of Dextran Degradation Mechanism by Streptococcus mutans Dextranase Belonging to Glycoside Hydrolase Family 66*

N. Suzuki, M. Okuyama, H. Mori, 2012, The Journal of Biological Chemistry.

The loop structure of Actinomycete glycoside hydrolase family 5 mannanases governs substrate recognition

M. Yao, Yuya Kumagai, T. Hatanaka, 2015, The FEBS journal.

Function-unknown Glycoside Hydrolase Family 31 Proteins, mRNAs of which were Expressed in Rice Ripening and Germinating Stages, are α-Glucosidase and α-Xylosidase

M. Okuyama, H. Mori, A. Kimura, 2007 .

Molecular insight into regioselectivity of transfructosylation catalyzed by GH68 levansucrase and β-fructofuranosidase

M. Okuyama, A. Kimura, W. Lang, 2021, The Journal of biological chemistry.

Formulation and evaluation of a novel megalomeric microemulsion from tamarind seed xyloglucan-megalosaccharides for improved high-dose quercetin delivery

M. Okuyama, A. Kimura, N. Sakairi, 2022, Food Hydrocolloids.

Molecular insights into the mechanism of thermal stability of actinomycete mannanase

Yuya Kumagai, T. Hatanaka, M. Okuyama, 2016, FEBS letters.

Kinetic properties and substrate inhibition of α-galactosidase from Aspergillus niger

M. Okuyama, H. Mori, A. Kimura, 2016, Bioscience, biotechnology, and biochemistry.

Purification, Characterization, and Sequence Analysis of Two α-Amylase Isoforms from Azuki Bean, Vigna angularis, Showing Different Affinity towards β-Cyclodextrin Sepharose

M. Okuyama, W. Saburi, H. Mori, 2003 .

Engineered dextranase from Streptococcus mutans enhances the production of longer isomaltooligosaccharides

Yuya Kumagai, M. Okuyama, A. Kimura, 2018, Bioscience, biotechnology, and biochemistry.

Multiple forms of alpha-glucosidase in rice seeds (Oryza sativa L., var Nipponbare).

M. Okuyama, H. Mori, A. Kimura, 2007, Biochimie.

Partial depolymerization of tamarind seed xyloglucan and its functionality toward enhancing the solubility of curcumin.

M. Okuyama, A. Kimura, N. Sakairi, 2023, Carbohydrate Polymers.

Bacteroides thetaiotaomicron VPI‐5482 glycoside hydrolase family 66 homolog catalyzes dextranolytic and cyclization reactions

M. Okuyama, W. Saburi, H. Mori, 2012, The FEBS journal.

Novel Dextranase Catalyzing Cycloisomaltooligosaccharide Formation and Identification of Catalytic Amino Acids and Their Functions Using Chemical Rescue Approach*

N. Suzuki, R. Suzuki, M. Okuyama, 2012, The Journal of Biological Chemistry.

Purification and Characterization of α-Glucosidase I from Japanese Honeybee (Apis cerana japonica) and Molecular Cloning of Its cDNA

M. Okuyama, H. Mori, A. Kimura, 2006, Bioscience, biotechnology, and biochemistry.

Crystal structure and identification of amino acid residues for catalysis and binding of GH3 AnBX β-xylosidase from Aspergillus niger

M. Okuyama, A. Kimura, Yaw-Kuen Li, 2023, Applied Microbiology and Biotechnology.

Localization of α-Glucosidases I, II, and III in Organs of European Honeybees, Apis mellifera L., and the Origin of α-Glucosidase in Honey

M. Okuyama, H. Mori, A. Kimura, 2004 .

Localization of alpha-glucosidases I, II, and III in organs of European honeybees, Apis mellifera L., and the origin of alpha-glucosidase in honey.

M. Okuyama, H. Mori, A. Kimura, 2004, Bioscience, biotechnology, and biochemistry.

Efficient synthesis of α‐galactosyl oligosaccharides using a mutant Bacteroides thetaiotaomicron retaining α‐galactosidase (BtGH97b)

M. Yao, Ken-ichi Watanabe, M. Okuyama, 2017, The FEBS journal.

Effects of mutation of Asn694 in Aspergillus niger α-glucosidase on hydrolysis and transglucosylation

Yuya Kumagai, M. Okuyama, H. Mori, 2017, Applied Microbiology and Biotechnology.

Effects of mutation of Asn694 in Aspergillus niger α-glucosidase on hydrolysis and transglucosylation

Yuya Kumagai, M. Okuyama, H. Mori, 2017, Applied Microbiology and Biotechnology.

Evidence of Intramolecular Transglucosylation Catalyzed by an α-Glucosidase

M. Okuyama, H. Mori, A. Kimura, 2003 .

Structural elements to convert Escherichia coli α‐xylosidase (YicI) into α‐glucosidase

M. Okuyama, H. Mori, A. Kimura, 2006 .

Biodecolorization of a food azo dye by the deep sea Dermacoccus abyssi MT1.1(T) strain from the Mariana Trench.

M. Okuyama, H. Mori, A. Kimura, 2014, Journal of Environmental Management.

Structural insights reveal the second base catalyst of isomaltose glucohydrolase

Yoshikazu Tanaka, M. Yao, M. Okuyama, 2021, The FEBS journal.

Biochemical properties and substrate recognition mechanism of GH31 α-glucosidase from Bacillus sp. AHU 2001 with broad substrate specificity.

Yuya Kumagai, M. Okuyama, W. Saburi, 2015, Biochimie.

Heat treatment of curdlan enhances the enzymatic production of biologically active β-(1,3)-glucan oligosaccharides.

Yuya Kumagai, M. Okuyama, A. Kimura, 2016, Carbohydrate polymers.

Substrate recognition of the catalytic α-subunit of glucosidase II from Schizosaccharomyces pombe

Yuya Kumagai, M. Okuyama, A. Kimura, 2017, Bioscience, biotechnology, and biochemistry.

A novel glycoside hydrolase family 97 enzyme: Bifunctional β-l-arabinopyranosidase/α-galactosidase from Bacteroides thetaiotaomicron.

M. Yao, Yuya Kumagai, M. Okuyama, 2017, Biochimie.

Megalo-type α-1,6-glucosaccharides induce production of tumor necrosis factor α in primary macrophages via toll-like receptor 4 signaling.

S. Ishizuka, H. Hara, Yuya Kumagai, 2016, Biomedical research.