Soonsil Hyun

发表

Selective α-glucosidase substrates and inhibitors containing short aromatic peptidyl moieties.

Sangeun Park, Soonsil Hyun, S. Do, 2011, Bioorganic & medicinal chemistry letters.

Ferroelectricity in undoped-HfO2 thin films induced by deposition temperature control during atomic layer deposition

C. Hwang, Soonsil Hyun, M. Park, 2016 .

Study on the internal field and conduction mechanism of atomic layer deposited ferroelectric Hf0.5Zr0.5O2 thin films

C. Hwang, Soonsil Hyun, M. Park, 2015 .

Nonhemolytic Cell-Penetrating Peptides: Site Specific Introduction of Glutamine and Lysine Residues into the α-Helical Peptide Causes Deletion of Its Direct Membrane Disrupting Ability but Retention of Its Cell Penetrating Ability.

Soonsil Hyun, Jaehoon Yu, Yan Lee, 2016, Biomacromolecules.

Multimeric Amphipathic α‐Helical Sequences for Rapid and Efficient Intracellular Protein Transport at Nanomolar Concentrations

Soonsil Hyun, Jaehoon Yu, Yan Lee, 2018, Advanced science.

Reduction of Helical Content by Insertion of a Disulfide Bond Leads to an Antimicrobial Peptide with Decreased Hemolytic Activity

Soonsil Hyun, Jaehoon Yu, Heeyong Hwang, 2013, ChemMedChem.

Chemical-Mediated Targeted Protein Degradation in Neurodegenerative Diseases

Soonsil Hyun, Dongyun Shin, 2021, Life.

Disruption of Interactions between Hydrophobic Residues on Nonpolar Faces is a Key Determinant in Decreasing Hemolysis and Increasing Antimicrobial Activities of α‐Helical Amphipathic Peptides

Soonsil Hyun, Jaehoon Yu, Yuri Lee, 2013, ChemMedChem.

E ffect of C om bination C hem otherapy w ith D ocetaxel P lus C isplatin in P atients w ith A dvanced N on-Sm all C ell L ung C ancer

Soonsil Hyun, Hee Jung Kang, S. Bae, 2003 .

One-bead-one-compound screening approach to the identification of cyclic peptoid inhibitors of cyclophilin D as neuroprotective agents from mitochondrial dysfunction.

Na-Rae Park, Soonsil Hyun, Jaehoon Yu, 2021, Chemical communications.

DDS, 4,4′-diaminodiphenylsulfone, extends organismic lifespan

S. Park, Yunje Cho, Soonsil Hyun, 2010, Proceedings of the National Academy of Sciences.

b -Catenin recognizes a specific RNA motif in the cyclooxygenase-2 mRNA 3 0 -UTR and interacts with HuR in colon cancer cells

Soonsil Hyun, Su-Jin Jeong, H. K. Lee, 2012 .

Two helices in the third intracellular loop determine anoctamin 1 (TMEM16A) activation by calcium

H. C. Hartzell, Soonsil Hyun, Jaehoon Yu, 2014, Pflügers Archiv - European Journal of Physiology.

An approach to the construction of tailor-made amphiphilic peptides that strongly and selectively bind to hairpin RNA targets.

Su Jin Lee, J. Kieft, Soonsil Hyun, 2009, Journal of the American Chemical Society.

Proline Hinged Amphipathic α-Helical Peptide Sensitizes Gram-Negative Bacteria to Various Gram-Positive Antibiotics.

K. Kim, Soonsil Hyun, Jaehoon Yu, 2020, Journal of medicinal chemistry.

Apoptosis inducing, conformationally constrained, dimeric peptide analogs of KLA with submicromolar cell penetrating abilities.

Soonsil Hyun, Jaehoon Yu, Seonju Lee, 2014, Biomacromolecules.

Design and Optimization of an α-Helical Bundle Dimer Cell-Penetrating Peptide for In Vivo Drug Delivery.

Soonsil Hyun, Jaehoon Yu, D. Chung, 2022, Bioconjugate chemistry.

Amphiphilic helical peptides containing two acridine moieties display picomolar affinity toward HIV-1 RRE and TAR.

Soonsil Hyun, Jaehoon Yu, Hyun Jin Kim, 2008, Angewandte Chemie.

Photocrosslinking of RNA and PhotoMet‐Containing Amphiphilic α‐Helical Peptides

Soonsil Hyun, Jaehoon Yu, Areum Han, 2009, Chembiochem : a European journal of chemical biology.

A strategy for the design of selective RNA binding agents. Preparation and RRE RNA binding affinities of a neomycin-peptide nucleic acid heteroconjugate library.

Soonsil Hyun, Jaehoon Yu, Kyung Hyun Lee, 2006, Bioorganic & medicinal chemistry letters.

Screening of Pre-miRNA-155 Binding Peptides for Apoptosis Inducing Activity Using Peptide Microarrays.

Soonsil Hyun, Jaehoon Yu, I. Shin, 2016, Journal of the American Chemical Society.

An Amphiphilic Peptide Induces Apoptosis Through the miR29b-p53 Pathway in Cancer Cells

C. Shin, Soonsil Hyun, Jaehoon Yu, 2016, Molecular therapy. Nucleic acids.

An RNA aptamer that selectively recognizes symmetric dimethylation of arginine 8 in the histone H3 N-terminal peptide.

Soonsil Hyun, Jaehoon Yu, Kyung Hyun Lee, 2011, Nucleic acid therapeutics.

pH-Activatable cell penetrating peptide dimers for potent delivery of anticancer drug to triple-negative breast cancer.

Soonsil Hyun, Jaehoon Yu, Yan Lee, 2020, Journal of controlled release : official journal of the Controlled Release Society.

β-Catenin recognizes a specific RNA motif in the cyclooxygenase-2 mRNA 3′-UTR and interacts with HuR in colon cancer cells

Soonsil Hyun, Sunjoo Jeong, H. K. Lee, 2012, Nucleic acids research.

Tentacle type peptides as artificial lectins against sulfated Lewis X and A.

Soonsil Hyun, Jaehoon Yu, Jihye Park, 2008, Bioorganic & medicinal chemistry letters.

Selection and syntheses of tentacle type peptides as 'artificial' lectins against various cell-surface carbohydrates.

Soonsil Hyun, Jaehoon Yu, M. Kwon, 2007, Bioorganic & medicinal chemistry.

Methylation-mediated control of aurora kinase B and Haspin with epigenetically modified histone H3 N-terminal peptides.

Su Jin Lee, Soonsil Hyun, Jaehoon Yu, 2011, Bioorganic & medicinal chemistry.

Effects of Asymmetric Arginine Dimethylation on RNA‐Binding Peptides

Soonsil Hyun, Jaehoon Yu, Sunjoo Jeong, 2008, Chembiochem : a European journal of chemical biology.

Small-Molecule Inhibitors and Degraders Targeting KRAS-Driven Cancers

Soonsil Hyun, Dongyun Shin, 2021, International journal of molecular sciences.

Histone H3 N‐Terminal Peptide Binds Directly to Its Own mRNA: A Possible Mode of Feedback Inhibition to Control Translation

Soonsil Hyun, Jaehoon Yu, E. Yang, 2009, Chembiochem : a European journal of chemical biology.

Dicer Nuclease‐Promoted Production of Let7a‐1 MicroRNA Is Enhanced in the Presence of Tryptophan‐Containing Amphiphilic Peptides

S. Hohng, Soonsil Hyun, Jaehoon Yu, 2014, Chembiochem : a European journal of chemical biology.

Alpha-helical peptide containing N,N-dimethyl lysine residues displays low-nanomolar and highly specific binding to RRE RNA.

Soonsil Hyun, Jaehoon Yu, Sunjoo Jeong, 2007, Journal of the American Chemical Society.

Oligomer Formation Propensities of Dimeric Bundle Peptides Correlate with Cell Penetration Abilities

Yuno Lee, Changbong Hyeon, Soonsil Hyun, 2018, ACS central science.

An amphipathic cell penetrating peptide aids cell penetration of cyclosporin A and increases its therapeutic effect in an in vivo mouse model for dry eye disease.

Soonsil Hyun, Jaehoon Yu, K. Yoon, 2019, Chemical communications.

Two helices in the third intracellular loop determine anoctamin 1 (TMEM16A) activation by calcium

Min Ho Tak, H. Criss Hartzell, Jooyoung Jung, 2014, Pflügers Archiv - European Journal of Physiology.

RNA Grooves Can Accommodate Disulfide‐Bridged Bundles of α‐Helical Peptides

Sangeun Park, Soonsil Hyun, Jaehoon Yu, 2010, Chembiochem : a European journal of chemical biology.

An approach to enhance specificity against RNA targets using heteroconjugates of aminoglycosides and chloramphenicol (or linezolid).

Soonsil Hyun, Jaehoon Yu, Sunjoo Jeong, 2004, Journal of the American Chemical Society.

Recent Progress in Modulation of WD40-Repeat Domain 5 Protein (WDR5): Inhibitors and Degraders

Soonsil Hyun, Dongyun Shin, Raju Gurung, 2023, Cancers.

An Amphiphilic Peptide Induces Apoptosis Through the miR29b-p53 Pathway in Cancer Cells.

C. Shin, Soonsil Hyun, Jaehoon Yu, 2016 .

Cell-penetrating, dimeric α-helical peptides: nanomolar inhibitors of HIV-1 transcription.

Soonsil Hyun, Jaehoon Yu, Seonju Lee, 2014, Angewandte Chemie.

Construction of histidine-containing hydrocarbon stapled cell penetrating peptides for in vitro and in vivo delivery of siRNAs

Soonsil Hyun, Jaehoon Yu, Dong-ki Lee, 2018, Chemical science.

RNA Grooves Can Accommodate Disulfide‐Bridged Bundles of α‐Helical Peptides

Sangeun Park, Soonsil Hyun, Jaehoon Yu, 2010, Chembiochem : a European journal of chemical biology.

De Novo Designed Cell-Penetrating Peptide Self-Assembly Featuring Distinctive Tertiary Structure

Soonsil Hyun, Jaehui Park, Soo Jae Lee, 2024, ACS omega.