Peiyuan Yao

发表

Manipulating the stereoselectivity of a thermostable alcohol dehydrogenase by directed evolution for efficient asymmetric synthesis of arylpropanols

M. Reetz, Yijie Dong, Peiyuan Yao, 2018, Biological chemistry.

An Unprecedented Effective Enzymatic Carboxylation of Phenols

Jie Ren, Peiyuan Yao, Qiaqing Wu, 2016 .

Simultaneous engineering of an enzyme's entrance tunnel and active site: the case of monoamine oxidase MAO-N† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c6sc05381e

M. Reetz, Pi Liu, Peiyuan Yao, 2017, Chemical science.

Chemoenzymatic Stereoselective Synthesis of Substituted γ‐ or δ‐lactams with Two Chiral Centers via Transaminase‐catalysed Dynamic Kinetic Resolution

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2020, ChemCatChem.

Efficient selective hydrolysis of terephthalonitrile to 4-cyanobenzoic acid catalyzed by a novel nitrilase from Pantoea sp

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2018, Process Biochemistry.

Exploiting the aglycon promiscuity of glycosyltransferase Bs-YjiC from Bacillus subtilis and its application in synthesis of glycosides.

Peiyuan Yao, Yan Zeng, Yueming Zhu, 2017, Journal of biotechnology.

A rhodium(I)-catalyzed demethylation-cyclization of o-anisole-substituted ynamides in the synthesis of chiral 2-amido benzofurans.

R. Hsung, Peiyuan Yao, K. Zhao, 2007, Organic letters.

Efficient Biosynthesis of (R)‐ or (S)‐2‐Hydroxybutyrate from l‐Threonine through a Synthetic Biology Approach

Peiyuan Yao, Yunfeng Cui, Qiaqing Wu, 2016 .

Improving Catalytic Activity and Reversing Enantio‐Specificity of ω‐Transaminase by Semi‐Rational Engineering en Route to Chiral Bulky β‐Amino Esters

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2021, ChemCatChem.

2,3‐Dihydroxybenzoic Acid Decarboxylase from Fusarium oxysporum: Crystal Structures and Substrate Recognition Mechanism

R. Guo, Peiyuan Yao, Yunfeng Cui, 2020 .

New recombinant cyclohexylamine oxidase variants for deracemization of secondary amines by orthogonally assaying designed mutants with structurally diverse substrates

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2016, Scientific Reports.

Screening and characterization of a diverse panel of metagenomic imine reductases for biocatalytic reductive amination

Peiyuan Yao, S. Charnock, N. Turner, 2020, Nature Chemistry.

Nitrilase-catalyzed hydrolysis of 3-aminopropionitrile at high concentration with a tandem reaction strategy for shifting the reaction to β-alanine formation

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2015 .

Enzymatic Synthesis of a Key Intermediate for Rosuvastatin by Nitrilase‐Catalyzed Hydrolysis of Ethyl (R)‐4‐Cyano‐3‐hydroxybutyate at High Substrate Concentration

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2015 .

Biocatalytic desymmetrization of 3-substituted glutaronitriles by nitrilases. A convenient chemoenzymatic access to optically active (S)-Pregabalin and (R)-Baclofen

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2014, Science China Chemistry.

Creating a new benzaldehyde lyase for atom-economic synthesis of chiral 1,2,4-butanetriol and 2-aminobutane-1,4-diol from formaldehyde

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2022, Chem Catalysis.

Asymmetric Synthesis of Fused-Ring Tetrahydroisoquinolines and Tetrahydro-β-carbolines from 2-Arylethylamines via a Chemoenzymatic Approach.

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2022, Organic letters.

A new class of o-hydroxyaryl-substituted N-heterocyclic carbene ligands and their complexes with palladium

Peiyuan Yao, Hong-Xia Ren, Baiquan Wang, 2007 .

A sequential metal-catalyzed C-N bond formation in the synthesis of 2-amido-indoles.

R. Hsung, Peiyuan Yao, K. Zhao, 2008, Organic letters.

Accessing d‐Valine Synthesis by Improved Variants of Bacterial Cyclohexylamine Oxidase

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2018 .

Hydrolytic and Dehydratase Enzymes

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2020 .

Biocatalytic Route to Chiral 2-Substituted-1,2,3,4-Tetrahydroquinolines Using Cyclohexylamine Oxidase Muteins

Jie Ren, Peiyuan Yao, Qiaqing Wu, 2018 .

Synthesis of alpha-keto-imides via oxidation of ynamides.

Z. Al-Rashid, R. Hsung, Peiyuan Yao, 2008, The Journal of organic chemistry.

Efficient enzymatic synthesis of (S)-1-(3′-bromo-2′-methoxyphenyl)ethanol, the key building block of lusutrombopag

Peiyuan Yao, Yunfeng Cui, Qiaqing Wu, 2022, Green Synthesis and Catalysis.

Biocatalytic Access to 1,4-Diazepanes via Imine Reductase-Catalyzed Intramolecular Asymmetric Reductive Amination

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2020 .

Imine Reductase‐Catalyzed Enantioselective Reduction of Bulky α,β‐Unsaturated Imines en Route to a Pharmaceutically Important Morphinan Skeleton

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2018, Advanced Synthesis & Catalysis.

Methodology Development in Directed Evolution: Exploring Options when Applying Triple‐Code Saturation Mutagenesis

Beibei Liu, Ge Qu, Zhoutong Sun, 2018, Chembiochem : a European journal of chemical biology.

One‐Pot Enzymatic Synthesis of Cyclic Vicinal Diols from Aliphatic Dialdehydes via Intramolecular C−C Bond Formation and Carbonyl Reduction Using Pyruvate Decarboxylases and Alcohol Dehydrogenases

Peiyuan Yao, Yunfeng Cui, Qiaqing Wu, 2018, Advanced Synthesis & Catalysis.

Deracemization of 2-Methyl-1,2,3,4-Tetrahydroquinoline Using Mutant Cyclohexylamine Oxidase Obtained by Iterative Saturation Mutagenesis

Jie Ren, Peiyuan Yao, Qiaqing Wu, 2014 .

Improving the catalytic efficiency and stereoselectivity of a nitrilase from Synechocystis sp. PCC6803 by semi-rational engineering en route to chiral γ-amino acids

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2019, Catalysis Science & Technology.

Asymmetric Synthesis of Both Enantiomers of Dimethyl 2-Methylsuccinate by the Ene-Reductase-Catalyzed Reduction at High Substrate Concentration

Peiyuan Yao, Yunfeng Cui, Qiaqing Wu, 2022, Catalysts.

Inverting the enantiopreference of nitrilase-catalyzed desymmetric hydrolysis of prochiral dinitriles by reshaping the binding pocket with a "mirror-image" strategy.

Peiyuan Yao, Yunfeng Cui, Qiaqing Wu, 2020, Angewandte Chemie.

Efficient Biosynthesis of Ethyl (R)‐3‐Hydroxyglutarate through a One‐Pot Bienzymatic Cascade of Halohydrin Dehalogenase and Nitrilase

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2015 .

Exploring the synthetic applicability of a new carboxylic acid reductase from Segniliparus rotundus DSM 44985

Rui Zhang, Peiyuan Yao, Qiaqing Wu, 2015 .

Enzymatic synthesis of 3-hydroxypropionic acid at high productivity by using free or immobilized cells of recombinant Escherichia coli

Jie Ren, Peiyuan Yao, Qiaqing Wu, 2016 .

Efficient microbial synthesis of key steroidal intermediates from bio-renewable phytosterols by genetically modified Mycobacterium fortuitum strains

Rui Zhang, Peiyuan Yao, Qiaqing Wu, 2019, Green Chemistry.

New product identification in the sterol metabolism by an industrial strain Mycobacterium neoaurum NRRL B-3805

Rui Zhang, Yanhe Ma, Peiyuan Yao, 2018, Steroids.

Efficient biosynthesis of β-alanine with a tandem reaction strategy to eliminate amide by-product in the nitrilase-catalyzed hydrolysis

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2016 .

Development of β-Amino Acid Dehydrogenase for the Synthesis of β-Amino Acids via Reductive Amination of β-Keto Acids

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2015 .

Biochemical characterization and substrate profiling of a reversible 2,3-dihydroxybenzoic acid decarboxylase for biocatalytic Kolbe-Schmitt reaction.

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2018, Enzyme and microbial technology.

Simultaneous Preparation of (S)-2-Aminobutane and d-Alanine or d-Homoalanine via Biocatalytic Transamination at High Substrate Concentration

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2022, Organic Process Research & Development.

Stereocomplementary Synthesis of β‐Aryl Propanamines by Enzymatic Dynamic Kinetic Resolution‐Reductive Amination

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2023, European Journal of Organic Chemistry.

Simultaneous engineering of an enzyme's entrance tunnel and active site: the case of monoamine oxidase MAO-N† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c6sc05381e

M. Reetz, Pi Liu, Peiyuan Yao, 2017, Chemical science.

Manipulating the stereoselectivity of a thermostable alcohol dehydrogenase by directed evolution for efficient asymmetric synthesis of arylpropanols

M. Reetz, Yijie Dong, Peiyuan Yao, 2018, Biological chemistry.

Stereocomplementary Synthesis of a Key Intermediate for Tofacitinib via Enzymatic Dynamic Kinetic Resolution‐Reductive Amination

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2022, Advanced Synthesis & Catalysis.