Dunming Zhu

发表

Manipulating the stereoselectivity of a thermostable alcohol dehydrogenase by directed evolution for efficient asymmetric synthesis of arylpropanols

M. Reetz, Yijie Dong, Peiyuan Yao, 2018, Biological chemistry.

Stereoselective ketone reduction by a carbonyl reductase from Sporobolomyces salmonicolor. Substrate specificity, enantioselectivity and enzyme-substrate docking studies.

Dunming Zhu, Yan Yang, J. Buynak, 2006, Organic & biomolecular chemistry.

Substrate profiling of cyclohexylamine oxidase and its mutants reveals new biocatalytic potential in deracemization of racemic amines

Qiaqing Wu, Dunming Zhu, Guangyue Li, 2013, Applied Microbiology and Biotechnology.

Thermal energy storage characteristics of Cu–H2O nanofluids

Dunming Zhu, Xia Li, Dunming Zhu, 2014 .

A sialic acid aldolase from Peptoclostridium difficile NAP08 with 4-hydroxy-2-oxo-pentanoate aldolase activity.

Yunfeng Cui, Qiaqing Wu, Dunming Zhu, 2016, Enzyme and microbial technology.

An Unprecedented Effective Enzymatic Carboxylation of Phenols

Jie Ren, Peiyuan Yao, Qiaqing Wu, 2016 .

Simultaneous engineering of an enzyme's entrance tunnel and active site: the case of monoamine oxidase MAO-N† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c6sc05381e

M. Reetz, Pi Liu, Peiyuan Yao, 2017, Chemical science.

A molecular modeling study on the enantioselectivity of aryl alkyl ketone reductions by a NADPH-dependent carbonyl reductase

Dunming Zhu, T. Cundari, L. Hua, 2007, Journal of molecular modeling.

Chemoenzymatic Stereoselective Synthesis of Substituted γ‐ or δ‐lactams with Two Chiral Centers via Transaminase‐catalysed Dynamic Kinetic Resolution

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2020, ChemCatChem.

Exploring the Synthetic Applicability of a Cyanobacterium Nitrilase as Catalyst for Nitrile Hydrolysis

Dunming Zhu, L. Hua, E. Biehl, 2006 .

Enzymatic nitrile hydrolysis catalyzed by nitrilase ZmNIT2 from maize. An unprecedented β-hydroxy functionality enhanced amide formation

Dunming Zhu, L. Hua, E. Biehl, 2006 .

Identification of a marine NADPH-dependent aldehyde reductase for chemoselective reduction of aldehydes

Jie Ren, Qiaqing Wu, Dunming Zhu, 2013 .

Alkylation of Pyridinium Acceptors via Thermal and Photoinduced Electron Transfer in Charge-Transfer Salts with Organoborates

Dunming Zhu, J. Kochi, 1999 .

Efficient selective hydrolysis of terephthalonitrile to 4-cyanobenzoic acid catalyzed by a novel nitrilase from Pantoea sp

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2018, Process Biochemistry.

Specialty Enzymes for Chemical Needs

Dunming Zhu, L. Hua, 2016 .

Characterization of (R)-selective amine transaminases identified by in silico motif sequence blast

Qiaqing Wu, Dunming Zhu, Dalong Zhang, 2015, Applied Microbiology and Biotechnology.

[Expression and characterization of a novel ω-transaminase from Burkholderia phytofirmans PsJN].

Qiaqing Wu, Dunming Zhu, Jinhui Feng, 2016, Sheng wu gong cheng xue bao = Chinese journal of biotechnology.

Comparison of a novel un-baffled and a conventional shell-and-tube dry-expansion evaporator

Dunming Zhu, Chenggang Lin, Yin Yingde, 2017 .

Flavin Oxidoreductase‐Mediated Regeneration of Nicotinamide Adenine Dinucleotide with Dioxygen and Catalytic Amount of Flavin Mononucleotide for One‐Pot Multi‐Enzymatic Preparation of Ursodeoxycholic Acid

Yunfeng Cui, Qiaqing Wu, Dunming Zhu, 2019, Advanced Synthesis & Catalysis.

Structural Analysis Reveals the Substrate‐Binding Mechanism for the Expanded Substrate Specificity of Mutant meso‐Diaminopimelate Dehydrogenase

R. Guo, Qiaqing Wu, Dunming Zhu, 2015, Chembiochem : a European journal of chemical biology.

Semi-rational engineering of cytochrome CYP153A from Marinobacter aquaeolei for improved ω-hydroxylation activity towards oleic acid

D. Mink, Zhanglin Lin, Dunming Zhu, 2016, Applied Microbiology and Biotechnology.

Efficient Biosynthesis of (R)‐ or (S)‐2‐Hydroxybutyrate from l‐Threonine through a Synthetic Biology Approach

Peiyuan Yao, Yunfeng Cui, Qiaqing Wu, 2016 .

Site-saturation mutagenesis of formate dehydrogenase from Candida bodinii creating effective NADP + -dependent FDH enzymes

Dunming Zhu, Weihua Wu, L. Hua, 2009 .

Improving Catalytic Activity and Reversing Enantio‐Specificity of ω‐Transaminase by Semi‐Rational Engineering en Route to Chiral Bulky β‐Amino Esters

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2021, ChemCatChem.

2,3‐Dihydroxybenzoic Acid Decarboxylase from Fusarium oxysporum: Crystal Structures and Substrate Recognition Mechanism

R. Guo, Peiyuan Yao, Yunfeng Cui, 2020 .

Highly enantioselective double reduction of phenylglyoxal to (R)-1-phenyl-1,2-ethanediol by one NADPH-dependent yeast carbonyl reductase with a broad substrate profile

S. Jia, Dunming Zhu, Yanhe Ma, 2013 .

Stereoselective synthesis using marine enzymes

Qiaqing Wu, Dunming Zhu, Jianjiong Li, 2013 .

How carbonyl reductases control stereoselectivity: Approaching the goal of rational design

Dunming Zhu, L. Hua, 2010 .

Enzymatic synthesis of d-alanine from a renewable starting material by co-immobilized dehydrogenases

Yunfeng Cui, Qiaqing Wu, Dunming Zhu, 2017 .

A new D-threonine aldolase as a promising biocatalyst for highly stereoselective preparation of chiral aromatic β-hydroxy-α-amino acids

Jie Ren, Yunfeng Cui, Qiaqing Wu, 2017 .

Biochemical characterization and substrate profiling of a new NADH-dependent enoate reductase from Lactobacillus casei.

Jie Ren, Qiaqing Wu, Dunming Zhu, 2012, Enzyme and microbial technology.

Cloning, Protein Sequence Clarification, and Substrate Specificity of a Leucine Dehydrogenase from Bacillus sphaericus ATCC4525

Dunming Zhu, L. Hua, Hongmei Li, 2009, Applied biochemistry and biotechnology.

Modulating the active site lid of an alcohol dehydrogenase from Ralstonia sp. enabled efficient stereospecific synthesis of 17β-hydroxysteroids.

Qiaqing Wu, Dunming Zhu, Jinhui Feng, 2021, Enzyme and microbial technology.

New recombinant cyclohexylamine oxidase variants for deracemization of secondary amines by orthogonally assaying designed mutants with structurally diverse substrates

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2016, Scientific Reports.

Enzymatic Synthesis of Chiral 2-Hydroxy Carboxylic Acids

Qiaqing Wu, Dunming Zhu, Xi Chen, 2015 .

Biocatalytic asymmetric amination of carbonyl functional groups – a synthetic biology approach to organic chemistry

Dunming Zhu, L. Hua, 2009, Biotechnology journal.

Nitrilase-catalyzed hydrolysis of 3-aminopropionitrile at high concentration with a tandem reaction strategy for shifting the reaction to β-alanine formation

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2015 .

Enzymatic Synthesis of a Key Intermediate for Rosuvastatin by Nitrilase‐Catalyzed Hydrolysis of Ethyl (R)‐4‐Cyano‐3‐hydroxybutyate at High Substrate Concentration

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2015 .

Biocatalytic desymmetrization of 3-substituted glutaronitriles by nitrilases. A convenient chemoenzymatic access to optically active (S)-Pregabalin and (R)-Baclofen

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2014, Science China Chemistry.

Efficient reductive desymmetrization of bulky 1,3-cyclodiketones enabled by structure-guided directed evolution of a carbonyl reductase

Sílvia Osuna, Miguel A. Maria-Solano, R. Guo, 2019, Nature Catalysis.

Creating a new benzaldehyde lyase for atom-economic synthesis of chiral 1,2,4-butanetriol and 2-aminobutane-1,4-diol from formaldehyde

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2022, Chem Catalysis.

Biotransformations of steroids to testololactone by a multifunctional strain Penicillium simplicissimum WY134-2

Qiaqing Wu, Dunming Zhu, Yanhe Ma, 2014 .

Effective multi-step functional biotransformations of steroids by a newly isolated Fusarium oxysporum SC1301

Jie Ren, Qiaqing Wu, Dunming Zhu, 2013 .

Regio- and stereoselective reduction of 17-oxosteroids to 17β-hydroxysteroids by a yeast strain Zygowilliopsis sp. WY7905

Qiaqing Wu, Dunming Zhu, Yanhe Ma, 2017, Steroids.

A recombinant ketoreductase tool-box. Assessing the substrate selectivity and stereoselectivity toward the reduction of β-ketoesters

Dunming Zhu, J. Rozzell, S. Kambourakis, 2006 .

Enzymatic hydrogenation of diverse activated alkenes. Identification of two Bacillus old yellow enzymes with broad substrate profiles

Jie Ren, Qiaqing Wu, Dunming Zhu, 2014 .

Studies on organolanthanide complexes: XLVI. Synthesis and characterization of N-containing ring-linked biscyclopentadienyl lanthanide and yttrium chlorides

Dunming Zhu, C. Qian, 1993 .

Asymmetric Synthesis of Fused-Ring Tetrahydroisoquinolines and Tetrahydro-β-carbolines from 2-Arylethylamines via a Chemoenzymatic Approach.

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2022, Organic letters.

Studies on organolanthanide complexes. Part 55. Synthesis of furan-bridged bis(cyclopentadienyl) lanthanide and yttrium chlorides, and ligand and metal tuning of reactivity of organolanthanide hydrides (in situ)

Dunming Zhu, C. Qian, 1994 .

Unexpected stereorecognition in nitrilase-catalyzed hydrolysis of beta-hydroxy nitriles.

Dunming Zhu, L. Hua, E. Biehl, 2006, Organic letters.

Asymmetric synthesis of both antipodes of beta-hydroxy nitriles and beta-hydroxy carboxylic acids via enzymatic reduction or sequential reduction/hydrolysis.

Haribabu Ankati, Dunming Zhu, Dunming Zhu, 2009, The Journal of organic chemistry.

Accessing d‐Valine Synthesis by Improved Variants of Bacterial Cyclohexylamine Oxidase

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2018 .

Substrate profiling of cyclohexylamine oxidase and its mutants reveals new biocatalytic potential in deracemization of racemic amines

Qiaqing Wu, Dunming Zhu, Guangyue Li, 2014, Applied Microbiology and Biotechnology.

Enantioselective Reduction of Diaryl Ketones Catalyzed by a Carbonyl Reductase from Sporobolomyces salmonicolor and its Mutant Enzymes

Dunming Zhu, L. Hua, Hongmei Li, 2009 .

Hydrolytic and Dehydratase Enzymes

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2020 .

Synthesis of optically pure 2-azido-1-arylethanols with isolated enzymes and conversion to triazole-containing beta-blocker analogues employing click chemistry.

Dunming Zhu, Yan Yang, L. Hua, 2008, The Journal of organic chemistry.

Biocatalytic Route to Chiral 2-Substituted-1,2,3,4-Tetrahydroquinolines Using Cyclohexylamine Oxidase Muteins

Jie Ren, Peiyuan Yao, Qiaqing Wu, 2018 .

Synthesis of single stereoisomers of 2,2-disubstituted 3-hydroxycyclohexane-1-ones via enzymatic desymmetric reduction of the 1,3-cyclohexanediones

Yunfeng Cui, Qiaqing Wu, Dunming Zhu, 2021 .

[Molecular cloning and characterization of a N-acetylneuraminate lyase gene from Staphylococcus hominis].

Dunming Zhu, D. Xiao, Jinhui Feng, 2013, Sheng wu gong cheng xue bao = Chinese journal of biotechnology.

Chemistry of C-Trimethylsilyl-Substituted Heterocarboranes. 24. Synthetic, Spectroscopic, Structural, and Reactivity Studies on Half- and Full-Sandwich Yttracarboranes of 2,3-C2B4- and 2,4-C2B4-Carborane Ligands

Dunming Zhu, N. Hosmane, J. Maguire, 1998 .

[Cloning and characterization of a novel carbonyl reductase for asymmetric reduction of bulky diaryl ketones].

S. Jia, Qiaqing Wu, Dunming Zhu, 2013, Sheng wu gong cheng xue bao = Chinese journal of biotechnology.

Semi–Rational Engineering a Carbonyl Reductase for the Enantioselective Reduction of β-Amino Ketones

Qiaqing Wu, Dunming Zhu, Dalong Zhang, 2015 .

Enzymatic hydrogen transfer reduction of α-chloro aromatic ketones catalyzed by a hyperthermophilic alcohol dehydrogenase

Dunming Zhu, L. Hua, B. Hyatt, 2009 .

Synthesis of optically active α-bromohydrins via reduction of α-bromoacetophenone analogues catalyzed by an isolated carbonyl reductase

Jie Ren, Qiaqing Wu, Dunming Zhu, 2012 .

Enzymatic enantioselective reduction of α-ketoesters by a thermostable 7α-hydroxysteroid dehydrogenase from Bacteroides fragilis

Dunming Zhu, Dunming Zhu, L. Hua, 2006 .

Asymmetric ketone reduction by a hyperthermophilic alcohol dehydrogenase. The substrate specificity, enantioselectivity and tolerance of organic solvents

Dunming Zhu, L. Hua, Hiba T. Malik, 2006 .

Stereoselective enzymatic synthesis of chiral alcohols with the use of a carbonyl reductase from Candida magnoliae with anti-Prelog enantioselectivity.

Dunming Zhu, Yan Yang, L. Hua, 2006, The Journal of organic chemistry.

Efficient enzymatic synthesis of (S)-1-(3′-bromo-2′-methoxyphenyl)ethanol, the key building block of lusutrombopag

Peiyuan Yao, Yunfeng Cui, Qiaqing Wu, 2022, Green Synthesis and Catalysis.

Biocatalytic Access to 1,4-Diazepanes via Imine Reductase-Catalyzed Intramolecular Asymmetric Reductive Amination

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2020 .

Imine Reductase‐Catalyzed Enantioselective Reduction of Bulky α,β‐Unsaturated Imines en Route to a Pharmaceutically Important Morphinan Skeleton

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2018, Advanced Synthesis & Catalysis.

Highly Atom Economic Synthesis of d‐2‐Aminobutyric Acid through an In Vitro Tri‐enzymatic Catalytic System

Yunfeng Cui, Qiaqing Wu, Dunming Zhu, 2017, ChemistryOpen.

Studies on organolanthanide complexes. XXIII, Reaction of organic halides with tricyclopentadienyllanthanides/sodium hydride

Dunming Zhu, C. Qian, Yongjie Gu, 1991 .

X-ray Crystal Structures and the Facile Oxidative (Au−C) Cleavage of the Dimethylaurate(I) and Tetramethylaurate(III) Homologues

Dunming Zhu, S. Lindeman, J. Kochi, 1999 .

One‐Pot Enzymatic Synthesis of Cyclic Vicinal Diols from Aliphatic Dialdehydes via Intramolecular C−C Bond Formation and Carbonyl Reduction Using Pyruvate Decarboxylases and Alcohol Dehydrogenases

Peiyuan Yao, Yunfeng Cui, Qiaqing Wu, 2018, Advanced Synthesis & Catalysis.

CHEMISTRY OF C-TRIMETHYLSILYL-SUBSTITUTED HETEROCARBORANES. XVIII: SYNTHETIC, SPECTROSCOPIC, REACTIVITY, AND BONDING STUDIES ON THE GROUP 13 ELEMENT M ETALLACARBORANES : CRYSTAL STRUCTURES OF 1-(CME3)-1-GA(2,2'-C10H8N2)-2,3-(S IME3)2-2,3-C2B4H4, 1-(CME3)-1-GA(L)-2,4-(SIME3)2-2,4-C2B4H4 L = 2,2'-C10H

A. Saxena, Dunming Zhu, N. Hosmane, 1995 .

Sandwiched Metallacarboranes of f-Block Elements

Dunming Zhu, N. Hosmane, J. Maguire, 1994 .

Deracemization of 2-Methyl-1,2,3,4-Tetrahydroquinoline Using Mutant Cyclohexylamine Oxidase Obtained by Iterative Saturation Mutagenesis

Jie Ren, Peiyuan Yao, Qiaqing Wu, 2014 .

Improving the catalytic efficiency and stereoselectivity of a nitrilase from Synechocystis sp. PCC6803 by semi-rational engineering en route to chiral γ-amino acids

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2019, Catalysis Science & Technology.

Asymmetric Synthesis of Both Enantiomers of Dimethyl 2-Methylsuccinate by the Ene-Reductase-Catalyzed Reduction at High Substrate Concentration

Peiyuan Yao, Yunfeng Cui, Qiaqing Wu, 2022, Catalysts.

Substrate profile of an ω-transaminase from Burkholderia vietnamiensis and its potential for the production of optically pure amines and unnatural amino acids

Qiaqing Wu, Dunming Zhu, Jinhui Feng, 2014 .

Yttrium compounds: new catalysts for the regioselective acylative cleavage of epoxides

Dunming Zhu, C. Qian, 1994 .

Regioselective acylative cleavage of cyclic ethers catalyzed by rare earth compounds

Dunming Zhu, C. Qian, Xiaowen Yang, 1994 .

Synthesis of optically active dihydrocarveol via a stepwise or one-pot enzymatic reduction of (R)- and (S)-carvone

Qiaqing Wu, Dunming Zhu, Xiuzhen Gao, 2012 .

Inverting the enantiopreference of nitrilase-catalyzed desymmetric hydrolysis of prochiral dinitriles by reshaping the binding pocket with a "mirror-image" strategy.

Peiyuan Yao, Yunfeng Cui, Qiaqing Wu, 2020, Angewandte Chemie.

Highly enantioselective mutant carbonyl reductases created via structure-based site-saturation mutagenesis.

K. Kantardjieff, Dunming Zhu, Yan Yang, 2010, The Journal of organic chemistry.

Inverting the enantioselectivity of a carbonyl reductase via substrate-enzyme docking-guided point mutation.

K. Kantardjieff, Dunming Zhu, Yan Yang, 2008, Organic letters.

Enzymatic Enantioselective Reduction of α-Ketoesters by a Thermostable 7α-Hydroxysteroid Dehydrogenase from Bacteroides fragilis.

Dunming Zhu, L. Hua, J. E. Stearns, 2006 .

Molecular Basis for the High Activity and Enantioselectivity of the Carbonyl Reductase from Sporobolomyces salmonicolor toward α-Haloacetophenones

Qiaqing Wu, Dunming Zhu, Jinhui Feng, 2018 .

Structure-Guided Directed Evolution of a Carbonyl Reductase Enables the Stereoselective Synthesis of (2S,3S)-2,2-Disubstituted-3-hydroxycyclopentanones via Desymmetric Reduction.

Yunfeng Cui, Qiaqing Wu, Dunming Zhu, 2020, Organic letters.

How carbonyl reductases control stereoselectivity: Approaching the goal of rational design*

Dunming Zhu, L. Hua, 2008 .

Microbial stereospecific reduction of 3-quinuclidinone with newly isolated Nocardia sp. and Rhodococcus erythropolis

Qiaqing Wu, Dunming Zhu, Yu Wang, 2013 .

Isolation and characterization of a novel Rhodococcus strain with switchable carbonyl reductase and para-acetylphenol hydroxylase activities

Qiaqing Wu, Dunming Zhu, Rui Zhang, 2012, Journal of Industrial Microbiology & Biotechnology.

Efficient Biosynthesis of Ethyl (R)‐3‐Hydroxyglutarate through a One‐Pot Bienzymatic Cascade of Halohydrin Dehalogenase and Nitrilase

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2015 .

‘Green’ synthesis of important pharmaceutical building blocks: enzymatic access to enantiomerically pure α-chloroalcohols

Dunming Zhu, L. Hua, Chandrani Mukherjee, 2005 .

Improving and Inverting Cβ-Stereoselectivity of Threonine Aldolase via Substrate-Binding-Guided Mutagenesis and a Stepwise Visual Screening

Qiaqing Wu, Dunming Zhu, Yanhe Ma, 2019, ACS Catalysis.

Characterization of (R)-selective amine transaminases identified by in silico motif sequence blast

Qiaqing Wu, Dunming Zhu, Dalong Zhang, 2015, Applied Microbiology and Biotechnology.

Highly Diastereoselective Synthesis of 2,2-Disubstituted Cyclopentane-1,3-diols via Stepwise Ketone Reduction Enabling Concise Chirality Construction.

Qiaqing Wu, Dunming Zhu, Jinhui Feng, 2020, The Journal of organic chemistry.

Enantioselective enzymatic reductions of sterically bulky aryl alkyl ketones catalyzed by a NADPH-dependent carbonyl reductase.

Dunming Zhu, L. Hua, 2006, The Journal of organic chemistry.

Asymmetric reduction of beta-ketonitriles with a recombinant carbonyl reductase and enzymatic transformation to optically pure beta-hydroxy carboxylic acids.

Dunming Zhu, Yan Yang, L. Hua, 2007, Organic letters.

Characterization of new recombinant 3-ketosteroid-Δ1-dehydrogenases for the biotransformation of steroids

Qiaqing Wu, Dunming Zhu, Yanhe Ma, 2017, Applied Microbiology and Biotechnology.

Exploring the synthetic applicability of a new carboxylic acid reductase from Segniliparus rotundus DSM 44985

Rui Zhang, Peiyuan Yao, Qiaqing Wu, 2015 .

Chemistry of C-Trimethylsilyl-Substituted Heterocarboranes. 28. Selective Alkylation and Reactivity of “Carbons Adjacent” and “Carbons Apart” Tetracarba-nido-dodecaborane(12) Derivatives toward Group 1 and Group 2 Metals. Synthetic, Spectroscopic, and Structural Investigations on Lithium-, Sodium-,

W. Lipscomb, Dunming Zhu, F. Baumann, 2000 .

A facile synthesis of oxazolidinones via lanthanide-catalyzed cycloaddition of epoxides with isocyanates

Dunming Zhu, C. Qian, 1994 .

A Facile Synthesis of Oxazolidinones via Lanthanide-Catalyzed Cycloaddition of Epoxides with Isocyanates.

Dunming Zhu, C. Qian, 1994 .

Structural and Mutational Studies on the Unusual Substrate Specificity of meso‐Diaminopimelate Dehydrogenase from Symbiobacterium thermophilum

R. Guo, Qiaqing Wu, Dunming Zhu, 2014, Chembiochem : a European journal of chemical biology.

A Novel meso-Diaminopimelate Dehydrogenase from Symbiobacterium thermophilum: Overexpression, Characterization, and Potential for d-Amino Acid Synthesis

Qiaqing Wu, Dunming Zhu, Xiuzhen Gao, 2012, Applied and Environmental Microbiology.

Distinct Regioselectivity of Fungal P450 Enzymes for Steroidal Hydroxylation

Qiaqing Wu, Dunming Zhu, Yanhe Ma, 2019, Applied and Environmental Microbiology.

Enzymatic synthesis of 3-hydroxypropionic acid at high productivity by using free or immobilized cells of recombinant Escherichia coli

Jie Ren, Peiyuan Yao, Qiaqing Wu, 2016 .

A Fungal P450 Enzyme from Thanatephorus cucumeris with Steroid Hydroxylation Capabilities

Qiaqing Wu, Dunming Zhu, Y. Bao, 2018, Applied and Environmental Microbiology.

Efficient microbial synthesis of key steroidal intermediates from bio-renewable phytosterols by genetically modified Mycobacterium fortuitum strains

Rui Zhang, Peiyuan Yao, Qiaqing Wu, 2019, Green Chemistry.

New product identification in the sterol metabolism by an industrial strain Mycobacterium neoaurum NRRL B-3805

Rui Zhang, Yanhe Ma, Peiyuan Yao, 2018, Steroids.

Discovery of a mandelonitrile hydrolase from Bradyrhizobium japonicum USDA110 by rational genome mining.

Dunming Zhu, Dunming Zhu, L. Hua, 2007, Journal of biotechnology.

Evaluation of substituent effects on activity and enantioselectivity in the enzymatic reduction of aryl ketones

Dunming Zhu, J. Rozzell, L. Hua, 2005 .

Biotechnological Products and Process Engineering

Rui Zhang, Qiaqing Wu, Dunming Zhu, 2022 .

Highly Efficient Synthesis of Optically Pure (S)-1-phenyl-1,2-ethanediol by a Self-Sufficient Whole Cell Biocatalyst

Yunfeng Cui, Qiaqing Wu, Dunming Zhu, 2015, ChemistryOpen.

A New 3-Ketosteroid-Δ1–Dehydrogenase with High Activity and Broad Substrate Scope for Efficient Transformation of Hydrocortisone at High Substrate Concentration

Rui Zhang, Qiaqing Wu, Dunming Zhu, 2022, Microorganisms.

The function of steroid terminal monooxygenase in cholesterol or phytosterol degradation by the Mycobacterium neoaurum NRRL B-3805

Qiaqing Wu, Dunming Zhu, Jinhui Feng, 2023, Systems Microbiology and Biomanufacturing.

A new nitrilase from Bradyrhizobium japonicum USDA 110. Gene cloning, biochemical characterization and substrate specificity.

Dunming Zhu, D. Gallagher, Dunming Zhu, 2008, Journal of biotechnology.

Efficient biosynthesis of β-alanine with a tandem reaction strategy to eliminate amide by-product in the nitrilase-catalyzed hydrolysis

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2016 .

Structure-guided engineering of meso-diaminopimelate dehydrogenase for enantioselective reductive amination of sterically bulky 2-keto acids

Qiaqing Wu, Dunming Zhu, Jinhui Feng, 2018 .

Engineering the meso-Diaminopimelate Dehydrogenase from Symbiobacterium thermophilum by Site Saturation Mutagenesis for d-Phenylalanine Synthesis

Qiaqing Wu, Dunming Zhu, F. Huang, 2013, Applied and Environmental Microbiology.

Enzymatic ketone reduction: mapping the substrate profile of a short-chain alcohol dehydrogenase (YMR226c) from Saccharomyces cerevisiae

Dunming Zhu, Yan Yang, L. Hua, 2007 .

Development of β-Amino Acid Dehydrogenase for the Synthesis of β-Amino Acids via Reductive Amination of β-Keto Acids

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2015 .

Biochemical characterization and substrate profiling of a reversible 2,3-dihydroxybenzoic acid decarboxylase for biocatalytic Kolbe-Schmitt reaction.

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2018, Enzyme and microbial technology.

Asymmetric Synthesis of Both Antipodes of β-Hydroxy Nitriles and β-Hydroxy Carboxylic Acids via Enzymatic Reduction or Sequential Reduction/Hydrolysis.

Dunming Zhu, Yan Yang, L. Hua, 2009 .

Engineering of l-threonine aldolase for the preparation of 4-(methylsulfonyl)phenylserine, an important intermediate for the synthesis of florfenicol and thiamphenicol.

Qiaqing Wu, Dunming Zhu, Jinhui Feng, 2020, Enzyme and microbial technology.

Flipping the Substrate Creates a Highly Selective Halohydrin Dehalogenase for the Synthesis of Chiral 4-Aryl-2-oxazolidinones from Readily Available Epoxides

Qiaqing Wu, Dunming Zhu, Jinhui Feng, 2023, ACS Catalysis.

Desymmetric Reductive Amination of 1,3-Cyclopentadiones to Single Stereoisomer of β-Amino Ketones with an All-Carbon Quaternary Stereocenter by Engineered Amine Dehydrogenases

Qiaqing Wu, Dunming Zhu, Yanhe Ma, 2023, ACS Catalysis.

Simultaneous Preparation of (S)-2-Aminobutane and d-Alanine or d-Homoalanine via Biocatalytic Transamination at High Substrate Concentration

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2022, Organic Process Research & Development.

Biotransformation Enables Innovations toward Green Synthesis of Steroidal Pharmaceuticals.

Qiaqing Wu, Dunming Zhu, Yanhe Ma, 2022, ChemSusChem.

The Enzymes that beyond Non-Oxidative Glycolysis

Qiaqing Wu, Dunming Zhu, Zixiang Xu, 2018, bioRxiv.

Find_tfSBP: find thermodynamics-feasible and smallest balanced pathways with high yield from large-scale metabolic networks

Zixiang Xu, Jibin Sun, Qiaqing Wu, 2017, Scientific Reports.

Stereocomplementary Synthesis of β‐Aryl Propanamines by Enzymatic Dynamic Kinetic Resolution‐Reductive Amination

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2023, European Journal of Organic Chemistry.

[Green biosynthesis of chiral pharmaceutical chemicals].

Qiaqing Wu, Dunming Zhu, Fengli Wu, 2022, Sheng wu gong cheng xue bao = Chinese journal of biotechnology.

Simultaneous engineering of an enzyme's entrance tunnel and active site: the case of monoamine oxidase MAO-N† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c6sc05381e

M. Reetz, Pi Liu, Peiyuan Yao, 2017, Chemical science.

Mutagenesis for d-Phenylalanine Synthesis thermophilum by Site Saturation Dehydrogenase from Symbiobacterium -Diaminopimelate meso Engineering the

Qiaqing Wu, Dunming Zhu, F. Huang, 2014 .

[Construction of strains for bioconversion of steroid key intermediates and intelligent industrial production].

Qiaqing Wu, Dunming Zhu, Jinhui Feng, 2022, Sheng wu gong cheng xue bao = Chinese journal of biotechnology.

Engineering a Carbonyl Reductase for Scalable Preparation of (S)‐3‐Cyclopentyl‐3‐hydroxypropanenitrile, the Key Building Block of Ruxolitinib

Yunfeng Cui, Qiaqing Wu, Dunming Zhu, 2021, Chembiochem : a European journal of chemical biology.

Crystal Structures and Catalytic Mechanism of l-erythro-3,5-Diaminohexanoate Dehydrogenase and Rational Engineering for Asymmetric Synthesis of β-Amino Acids.

Qiaqing Wu, Dunming Zhu, Jiahai Zhou, 2021, Angewandte Chemie.

Characterization of new recombinant 3-ketosteroid-Δ1-dehydrogenases for the biotransformation of steroids

Qiaqing Wu, Dunming Zhu, Yanhe Ma, 2017, Applied Microbiology and Biotechnology.

Engineering a hydroxysteroid dehydrogenase to improve its soluble expression for the asymmetric reduction of cortisone to 11β-hydrocortisone

Qiaqing Wu, Dunming Zhu, Rui Zhang, 2014, Applied Microbiology and Biotechnology.

Manipulating the stereoselectivity of a thermostable alcohol dehydrogenase by directed evolution for efficient asymmetric synthesis of arylpropanols

M. Reetz, Yijie Dong, Peiyuan Yao, 2018, Biological chemistry.

Nitrilase-catalyzed selective hydrolysis of dinitriles and green access to the cyanocarboxylic acids of pharmaceutical importance

Dunming Zhu, Dunming Zhu, L. Hua, 2007 .

Efficient synthesis of (R)-4-methoxyamphetamine and its analogues under low ammonium concentration using engineered amine dehydrogenase

Qiaqing Wu, Dunming Zhu, Xi Chen, 2024, Molecular Catalysis.

Semirational Engineering of a Thermostable Carbonyl Reductase for the Precision Synthesis of (2R,3R)-2-Methyl-2-benzyl-3-hydroxycyclopentanone and Its Analogues.

Yunfeng Cui, Qiaqing Wu, Dunming Zhu, 2023, Journal of Organic Chemistry.

Discovery and directed evolution of C-C bond formation enzymes for the biosynthesis of β-hydroxy-α-amino acids and derivatives.

Qiaqing Wu, Dunming Zhu, Qijia Chen, 2024, Critical reviews in biotechnology.

Stereocomplementary Synthesis of a Key Intermediate for Tofacitinib via Enzymatic Dynamic Kinetic Resolution‐Reductive Amination

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2022, Advanced Synthesis & Catalysis.

Asymmetric Carbohydroxylation of Alkenes via Sequential Photocatalytic Oxo-Alkylation and Enzymatic Reduction

Qiaqing Wu, Dunming Zhu, Jinhui Feng, 2024, Tetrahedron Chem.

[High throughput screening of active and stereoselective carbonyl reductases].

Qiaqing Wu, Dunming Zhu, J. Bao, 2015, Sheng wu gong cheng xue bao = Chinese journal of biotechnology.

Reshaping the Substrate Binding Pocket of β-Amino Acid Dehydrogenase for the Synthesis of Aromatic β-Amino Acids.

Qiaqing Wu, Dunming Zhu, Jinhui Feng, 2023, Organic letters.

Enantiodivergent Synthesis of 1-Heteroaryl Tetrahydroisoquinolines Catalyzed by Imine Reductases.

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2023, Organic letters.