Guangyue Li

发表

Manipulating the stereoselectivity of a thermostable alcohol dehydrogenase by directed evolution for efficient asymmetric synthesis of arylpropanols

M. Reetz, Yijie Dong, Peiyuan Yao, 2018, Biological chemistry.

Inducing high activity of a thermophilic enzyme at ambient temperatures by directed evolution.

M. Reetz, Sílvia Osuna, Miguel A. Maria-Solano, 2017, Chemical communications.

Can Machine Learning Revolutionize Directed Evolution of Selective Enzymes?

Manfred T. Reetz, Guangyue Li, Yijie Dong, 2019, Advanced Synthesis & Catalysis.

Substrate profiling of cyclohexylamine oxidase and its mutants reveals new biocatalytic potential in deracemization of racemic amines

Qiaqing Wu, Dunming Zhu, Guangyue Li, 2013, Applied Microbiology and Biotechnology.

Learning lessons from directed evolution of stereoselective enzymes

M. Reetz, Guangyue Li, 2016 .

Improving the Yield of Xenocoumacin 1 Enabled by In Situ Product Removal

Yijie Dong, Guangyue Li, Jiaqi Duan, 2020, ACS omega.

Simultaneous engineering of an enzyme's entrance tunnel and active site: the case of monoamine oxidase MAO-N† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c6sc05381e

M. Reetz, Pi Liu, Peiyuan Yao, 2017, Chemical science.

Manipulating the stereoselectivity of the thermostable Baeyer-Villiger monooxygenase TmCHMO by directed evolution.

Maximilian J L J Fürst, M. Reetz, M. Fraaije, 2017, Organic & biomolecular chemistry.

Identification of a marine NADPH-dependent aldehyde reductase for chemoselective reduction of aldehydes

Jie Ren, Qiaqing Wu, Dunming Zhu, 2013 .

Machine Learning Enables Selection of Epistatic Enzyme Mutants for Stability Against Unfolding and Detrimental Aggregation

Xavier F. Cadet, F. Feixas, M. Reetz, 2020, Chembiochem : a European journal of chemical biology.

Biocatalytic Baeyer–Villiger Reactions: Uncovering the Source of Regioselectivity at Each Evolutionary Stage of a Mutant with Scrutiny of Fleeting Chiral Intermediates

M. Reetz, Guangyue Li, H. Yin, 2022, ACS Catalysis.

Improving the Yield of Xenocoumacin 1 by PBAD Promoter Replacement in Xenorhabdus nematophila CB6

Guangyue Li, Xiufen Yang, Youcai Qin, 2021, Agriculture.

New recombinant cyclohexylamine oxidase variants for deracemization of secondary amines by orthogonally assaying designed mutants with structurally diverse substrates

Peiyuan Yao, Qiaqing Wu, Dunming Zhu, 2016, Scientific Reports.

Recent progress in directed evolution of stereoselective monoamine oxidases

Yijie Dong, Guangyue Li, Jiaqi Duan, 2019, Bioresources and Bioprocessing.

Substrate profiling of cyclohexylamine oxidase and its mutants reveals new biocatalytic potential in deracemization of racemic amines

Qiaqing Wu, Dunming Zhu, Guangyue Li, 2014, Applied Microbiology and Biotechnology.

Biocatalytic Route to Chiral 2-Substituted-1,2,3,4-Tetrahydroquinolines Using Cyclohexylamine Oxidase Muteins

Jie Ren, Peiyuan Yao, Qiaqing Wu, 2018 .

Methodology Development in Directed Evolution: Exploring Options when Applying Triple‐Code Saturation Mutagenesis

Beibei Liu, Ge Qu, Zhoutong Sun, 2018, Chembiochem : a European journal of chemical biology.

Deracemization of 2-Methyl-1,2,3,4-Tetrahydroquinoline Using Mutant Cyclohexylamine Oxidase Obtained by Iterative Saturation Mutagenesis

Jie Ren, Peiyuan Yao, Qiaqing Wu, 2014 .

Imidazolium-based iodoacetamide functional tags: design, synthesis, and property study for cysteinyl-peptide analysis by mass spectrometry.

L. Zhang, Guangyue Li, Yukui Zhang, 2014, The Analyst.

Overriding Traditional Electronic Effects in Biocatalytic Baeyer-Villiger Reactions by Directed Evolution.

Maximilian J L J Fürst, K. Houk, M. Reetz, 2018, Journal of the American Chemical Society.

Enzymatic site-selectivity enabled by structure-guided directed evolution.

Manfred T. Reetz, Jian-bo Wang, Guangyue Li, 2017, Chemical communications.

Exploring the substrate scope of mutants derived from the robust alcohol dehydrogenase TbSADH

Zhoutong Sun, Guangyue Li, Guangyue Li, 2016 .

Biocatalysts for the pharmaceutical industry created by structure-guided directed evolution of stereoselective enzymes.

Guangyue Li, Guangyue Li, M. Reetz, 2017, Bioorganic & medicinal chemistry.

Multiparameter Optimization in Directed Evolution: Engineering Thermostability, Enantioselectivity, and Activity of an Epoxide Hydrolase

Manfred T. Reetz, Zhoutong Sun, Guangyue Li, 2016 .

Structure-Guided Triple-Code Saturation Mutagenesis: Efficient Tuning of the Stereoselectivity of an Epoxide Hydrolase

Manfred T. Reetz, Zhoutong Sun, Aitao Li, 2016 .

Catalytic Asymmetric Reduction of Difficult-to-Reduce Ketones: Triple Code Saturation Mutagenesis of an Alcohol Dehydrogenase

Manfred T. Reetz, Zhoutong Sun, Guangyue Li, 2016 .

A machine learning approach for reliable prediction of amino acid interactions and its application in the directed evolution of enantioselective enzymes

Frédéric Cadet, Nicolas Fontaine, Iyanar Vetrivel, 2018, Scientific Reports.