Jörgen Ådén

发表

NMR studies of protein dynamics and structure

Jörgen Ådén, 2010 .

Copper binding triggers compaction in N-terminal tail of human copper pump ATP7B.

Tanumoy Mondol, P. Wittung-Stafshede, Jörgen Ådén, 2016, Biochemical and biophysical research communications.

NMR identification of transient complexes critical to adenylate kinase catalysis.

M. Wolf-Watz, Jörgen Ådén, Jörgen Adén, 2007, Journal of the American Chemical Society.

Noncooperative folding of subdomains in adenylate kinase.

Marcus Wallgren, Ulrika Olsson, Louise Rundqvist, 2009, Biochemistry.

Modulation of a pre-existing conformational equilibrium tunes adenylate kinase activity.

Jörgen Ådén, Alexander Schug, A. Schug, 2012, Journal of the American Chemical Society.

Structural topology and activation of an initial adenylate kinase-substrate complex.

Anders Olofsson, Kristoffer Brännström, Jörgen Ådén, 2013, Biochemistry.

Intramolecular Povarov Reactions for the Synthesis of Chromenopyridine Fused 2-Pyridone Polyheterocycles Binding to α-Synuclein and Amyloid-β Fibrils

Jörgen Ådén, Pardeep Singh, M. Tyagi, 2020, The Journal of organic chemistry.

Direct observation of protein unfolded state compaction in the presence of macromolecular crowding.

Pernilla Wittung-Stafshede, P. Wittung-Stafshede, Jörgen Ådén, 2013, Biophysical journal.

The Small Molecule Alpha-Synuclein Aggregator, FN075, Enhances Alpha-Synuclein Pathology in Subclinical AAV Rat Models

A. Bemelmans, Jörgen Ådén, D. McKernan, 2021, Biomolecules.

Viral mimetic priming enhances α-synuclein-induced degeneration: Implications for Parkinson’s disease

Jörgen Ådén, D. McKernan, F. Almqvist, 2019, Brain, Behavior, and Immunity.

Bax to the future - A novel, high-yielding approach for purification and expression of full-length Bax protein for structural studies.

Jörgen Ådén, G. Gröbner, R. Stoll, 2019, Protein expression and purification.

Synthesis of Multiring Fused 2-Pyridones via a Nitrene Insertion Reaction: Fluorescent Modulators of α-Synuclein Amyloid Formation.

P. Wittung-Stafshede, Jörgen Ådén, Pardeep Singh, 2015, Organic letters.

Domain specific insight into the recognition of BH3-death motifs by the pro-survival Bcl-2 protein.

Jörgen Ådén, G. Gröbner, A. U. Mushtaq, 2022, Biophysical journal.

Neutron reflectometry and NMR spectroscopy of full-length Bcl-2 protein reveal its membrane localization and conformation

Jörgen Ådén, T. Sparrman, L. Clifton, 2021, Communications biology.

Bax Forms a Membrane Surface Protein-Lipid Complex as it Initiates Apoptosis

Jörgen Ådén, T. Sparrman, L. Clifton, 2022, bioRxiv.

Tandem Ring Opening/Intramolecular [2 + 2] Cycloaddition Reaction for the Synthesis of Cyclobutane Fused Thiazolino-2-Pyridones

Jörgen Ådén, M. Tyagi, A. Olofsson, 2021, The Journal of organic chemistry.

Pyridine-Fused 2-Pyridones via Povarov and A3 Reactions: Rapid Generation of Highly Functionalized Tricyclic Heterocycles Capable of Amyloid Fibril Binding.

Jörgen Ådén, Pardeep Singh, K. Brännström, 2019, The Journal of organic chemistry.

Synthesis of Densely Functionalized N-Alkenyl 2-Pyridones via Benzyne-Induced Ring Opening of Thiazolino-Fused 2-Pyridones.

U. Sauer, Jörgen Ådén, Pardeep Singh, 2019, Organic letters.

Helicobacter pylori Adapts to Chronic Infection and Gastric Disease via pH-Responsive BabA-Mediated Adherence.

M. Unemo, B. Chromy, L. Engstrand, 2017, Cell host & microbe.

Inhibition of curli assembly and Escherichia coli biofilm formation by the human systemic amyloid precursor transthyretin

M. Ivanova, M. Chapman, Jörgen Ådén, 2017, Proceedings of the National Academy of Sciences.

Bacterial Chaperones CsgE and CsgC Differentially Modulate Human α-Synuclein Amyloid Formation via Transient Contacts

M. Chapman, P. Wittung-Stafshede, Jörgen Ådén, 2015, PloS one.

The bacterial curli system possesses a potent and selective inhibitor of amyloid formation.

M. Chapman, P. Wittung-Stafshede, Jörgen Ådén, 2015, Molecular cell.

Backbone chemical shift assignment and dynamics of the N-terminal domain of ClpB from Francisella tularensis type VI secretion system

A. Sjöstedt, Jörgen Ådén, G. Gröbner, 2022, Biomolecular NMR assignments.

Extraordinary μs-ms backbone dynamics in Arabidopsis thaliana peroxiredoxin Q.

Alexander F. Christiansen, W. Schröder, M. Wolf-Watz, 2011, Biochimica et Biophysica Acta.

Protein-lipid interaction at low pH induces oligomerization of the MakA cytotoxin from Vibrio cholerae

A. Sjöstedt, Karina Persson, Jörgen Ådén, 2022, eLife.

Structural basis for catalytically restrictive dynamics of a high-energy enzyme state

U. Sauer, M. Wolf-Watz, Jörgen Ådén, 2015, Nature Communications.

Victor Guallar, Santiago Esteban-Martín, Robert Bryn Fenwick, 2014, PLoS Comput. Biol..

Dissociation between the critical role of ClpB of Francisella tularensis for the heat shock response and the DnaK interaction and its important role for efficient type VI secretion and bacterial virulence

I. Golovliov, A. Sjöstedt, Rajender Kumar, 2020, PLoS pathogens.

Protein-lipid interaction at low pH induces oligomerisation of the MakA cytotoxin from Vibrio cholerae

A. Sjöstedt, Karina Persson, Jörgen Ådén, 2021 .

Mechanistic Basis for a Connection between the Catalytic Step and Slow Opening Dynamics of Adenylate Kinase

K. Nam, M. Wolf-Watz, Jörgen Ådén, 2023, J. Chem. Inf. Model..

Human cytoplasmic copper chaperones Atox1 and CCS exchange copper ions in vitro

S. Petzoldt, P. Wittung-Stafshede, Jörgen Ådén, 2015, BioMetals.

Macromolecular crowding effects on two homologs of ribosomal protein s16: protein-dependent structural changes and local interactions.

P. Wittung-Stafshede, Jörgen Ådén, L. Johansson, 2014, Biophysical journal.

A Capped Peptide of the Aggregation Prone NAC 71–82 Amino Acid Stretch of α-Synuclein Folds into Soluble β-Sheet Oligomers at Low and Elevated Peptide Concentrations

Jörgen Ådén, P. Andersson, Thomas Näsström, 2020, International journal of molecular sciences.

Insight into Functional Membrane Proteins by Solution NMR: The Human Bcl-2 Protein—A Promising Cancer Drug Target

Jörgen Ådén, T. Sparrman, M. Hedenström, 2021, Molecules.

Creation of distinctive Bax-lipid complexes at mitochondrial membrane surfaces drives pore formation to initiate apoptosis

Jörgen Ådén, T. Sparrman, L. Clifton, 2023, Science advances.

Small pH and salt variations radically alter the thermal stability of metal-binding domains in the copper transporter, Wilson disease protein.

K. Nam, P. Wittung-Stafshede, Jörgen Ådén, 2013, The journal of physical chemistry. B.

Neutron reflectometry and NMR spectroscopy of full-length Bcl-2 protein reveal its membrane localization and conformation

Jörgen Ådén, T. Sparrman, L. Clifton, 2021, Communications Biology.

Folding of an unfolded protein by macromolecular crowding in vitro.

P. Wittung-Stafshede, Jörgen Ådén, 2014, Biochemistry.

Synthesis of Multiring Fused 2-Pyridones via a Nitrene Insertion Reaction: Fluorescent Modulators of α-Synuclein Amyloid Formation.

P. Wittung-Stafshede, Jörgen Ådén, Pardeep Singh, 2015, Organic letters.

Increased Brain Exposure of an Alpha-Synuclein Fibrillization Modulator by Utilization of an Activated Ester Prodrug Strategy.

A. Varrone, A. Takano, Jörgen Ådén, 2018, ACS chemical neuroscience.